Color Average Interaction Strength
      0 < i.s. ≤ 1
      1 < i.s. ≤ 2
      2 < i.s. ≤ 3
      3 < i.s. ≤ 4
      4 < i.s. ≤ 5
      5 < i.s. ≤ 6
      6 < i.s. ≤ 7
      7 < i.s. ≤ 8
      8 < i.s. ≤ 9
      9 < i.s. ≤ 10
Index Hub Avg Force Num Of Links Community Value
1I_II.3 5.8225400
2I_II.5 5.3525400
3II.4 6.815600
4II_III.2 5.4575470
5II_III.3 11.3075470
6III.2 7.246520
7III.3 8.895420
8III.4 7.3325400
9IV.4 3.715400
10IV_V.5 5.27400
11V.3 8.292500
12V.12 9.856500
13Finger.2 11.406500
14VI.6 9.1625400
15VI.13 8.1575400
16hI.7 5.3575400
17VII.1 6.382500
18VII.4 7.2625400
19VII_VIII.2 6.4625400
20VII_VIII.6 4.788500
21VII_VIII.7 5.475400
22Middle.1 5.725400
23IX.9 7.4400
24IX_X.11 5.3925400
25X.7 9.83333600
26X.8 7.538500
27X.10 7.3725400
28X_XI.4 5.5875400
29X_XI.6 4.2450
30XII.2 5.86450
31XII.9 4.65500
32XIII.2 9.29650
33XIV.1 8.63450
34XIV.2 4.01450
35XV.2 6.21420
36XV.6 4.24420
37XV.7 5.0775420
38XV.9 10.6575420
39XV.10 6.826520
40XV_XVI.6 7.91550
41XVI.2 7.905450
42XVI_XVII.4 6.2025400
43XVII.7 2.9450
44Lariat.1 3.715400
45Lariat.11 10.1275440
46Lariat.19 6.0525440
47Lariat.21 7.6625440
48Back.5 4.6875440
49XVIII.3 4.14254110
50XVIII.5 7.876676110
51XVIII.8 7.16500
52XVIII.9 4.4400
53XVIII.10 3.52754110
54XIX.9 4.556500
55A:A:F375 6.64333640
56A:A:R382 11.276540
57A:A:L385 3.44400
58A:A:Y391 8.1525400

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Force: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

Value: this column reports the value present in the user submitted external values file (if any).

Color Relative Recurrence (%)
      0 < rr ≤ 10
      10 < rr ≤ 20
      20 < rr ≤ 30
      30 < rr ≤ 40
      40 < rr ≤ 50
      50 < rr ≤ 60
      60 < rr ≤ 70
      70 < rr ≤ 80
      80 < rr ≤ 90
      90 < rr ≤ 100
Index Node1 Node2 Recurrency Force Hub1? Hub2? Community Value1 Value2
1IV.3 IV.4 30.9371.84NoYes000
2IV.3 VII.4 31.94866.02NoYes000
3II.5 VII.4 33.0023.65NoYes000
4II.5 III.2 33.89925.86NoYes500
5III.2 II_III.2 19.87393.58YesYes500
6III.3 II_III.2 20.72754.36YesYes500
7III.3 X_XI.1 44.563317.23YesNo000
8A:A:H357 X_XI.1 45.47519.55NoNo000
9A:A:H357 XIII_XIV.1 36.88817.91NoNo000
10XIII_XIV.1 XIX.11 60.677115.43NoNo000
11XIX.11 XVIII.5 60.939412.89NoYes000
12XV.10 XVIII.5 79.68616.91YesYes100
13Lariat.13 XV.10 71.78944.12NoYes000
14Lariat.13 Lariat.15 71.55175.71NoNo000
15Lariat.15 Lariat.4 69.88315.54NoNo000
16Lariat.10 Lariat.4 69.671313.36NoNo000
17Lariat.10 Lariat.19 68.66595.01NoYes000
18A:A:Y391 Lariat.19 65.08918.46YesYes600
19A:A:Y391 Lariat.20 76.52849.55YesNo000
20Lariat.20 Lariat.21 76.23947.86NoYes000
21A:A:R382 Lariat.21 75.36512.41YesYes000
22A:A:R382 II_III.3 73.168411.73YesYes200
23III.2 III_IV.6 19.80375.61YesNo500
24III.3 III_IV.6 20.230512.3YesNo500
25A:A:F380 II_III.3 72.17079.62NoYes200
26A:A:F380 X.4 72.188415.83NoNo000
27I.6 X.4 34.894.23NoNo000
28I.6 X.2 34.5224.55NoNo000
29II.3 X.4 36.98924.28NoNo000
30II.3 X.2 34.61189.22NoNo000
31I_II.1 X.2 68.33533.23NoNo000
32I_II.1 I_II.3 67.54244.42NoYes000
33I_II.3 I_II.5 16.88768.83YesYes000
34IX_X.13 I_II.3 25.76744.15NoYes000
35IX_X.14 I_II.3 25.76745.89NoYes000
36IV_V.5 I_II.5 10.67483.23YesYes000
37V.6 VII_VIII.2 12.27324.87NoYes000
38III.4 X.10 14.24159.14YesYes400
39VII_VIII.8 X.10 10.08559.16NoYes400
40A:A:H357 A:A:P358 13.23054.58NoNo000
41A:A:P358 XIII.3 13.075612.52NoNo000
42IV.4 VII.1 10.37964.76YesYes000
43IX_X.11 IX_X.13 24.08433.35YesNo000
44IX_X.11 IX_X.4 15.501711.27YesNo000
45IX.11 IX_X.4 10.36694.34NoNo000
46IX_X.11 IX_X.14 24.08433.56YesNo000
47IX_X.10 IX_X.11 30.97183.39NoYes000
48IX.9 IX_X.10 29.258912.56YesNo000
49IX.9 VI.9 18.93315.86YesNo800
50VI.7 VI.9 17.28855.86NoNo000
51IX.4 V.8 12.24359.78NoNo000
52V.8 VII_VIII.6 11.94766.35NoYes000
53VII_VIII.6 VII_VIII.7 10.60094.93YesYes000
54Middle.9 V.12 14.1298.36NoYes000
55V.12 XV_XVI.3 10.160814.89YesNo000
56Finger.2 Middle.9 13.948214.92YesNo000
57Back.5 VII_VIII.7 10.11348.39YesYes000
58Lariat_Back.2 X.10 24.86774.33NoYes000
59XIII.3 XIII_XIV.3 14.40726.73NoNo000
60XIX.9 XVIII.5 95.67015.16YesYes100
61XII.9 XIX.9 46.81743.65YesYes100
62XIII.2 XIII_XIV.3 14.13346.73YesNo100
63XII.9 XIII.2 14.07214.69YesYes100
64XII.9 XIV.3 56.25364.47YesNo100
65XIV.3 XV.6 1004.81NoYes000
66XIX.9 XVIII.7 44.48875.02YesNo100
67XIV.3 XVIII.7 44.29719.22NoNo100
68XV.6 XVII.7 90.91852.98YesYes000
69XVII.5 XVII.7 89.28412.82NoYes000
70XVII.5 XVI_XVII.2 88.707414.85NoNo000
71XVII.3 XVI_XVII.2 88.12953.98NoNo000
72XVII.3 XVI_XVII.4 87.55034.47NoYes000
73XIV.9 XVI_XVII.4 85.80525.91NoYes000
74XIV.9 XIV_XV.2 45.27918.77NoNo000
75XII.3 XIV.9 39.95274.12NoNo000
76XI.10 XII.3 39.32424.24NoNo000
77XI.10 XIV_XV.2 39.62276.02NoNo000
78XI.10 XVIII.13 77.63493.04NoNo000
79XIV_XV.4 XVIII.13 75.02864.55NoNo000
80XIV_XV.4 XVIII_XIX.2 72.41733.49NoNo000
81XVIII_XIX.1 XVIII_XIX.2 38.91323.71NoNo000
82XV.2 XVIII_XIX.1 29.62316.12YesNo000
83XVIII_XIX.2 XVIII_XIX.6 32.20474.91NoNo000
84XV.2 XVIII_XIX.6 29.53528.1YesNo1500
85XV.2 XVIII.12 56.48374.5YesNo000
86XV.3 XVIII.12 53.80673NoNo000
87XV.3 XVI.10 48.44879.45NoNo000
88XV.5 XVI.10 45.76789.45NoNo000
89XV.5 XVIII.10 43.08571.44NoYes000
90XVIII.10 XVIII.8 35.02344.31YesYes300
91XV.9 XVIII.8 18.871118.9YesYes300
92XV.9 XVI.3 13.49869.56YesNo300
93II.4 IV.4 10.38023.79YesYes000
94Lariat_Back.2 XIII_XIV.1 25.14915.58NoNo000
95A:A:Y391 Middle.1 12.01273.38YesYes600
96IX.4 X.8 11.139612.41NoYes400

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrency: the relative recurrency in the filtered pool of shortest paths.

Force: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

Value1, Value2: these columns report the values present in the user submitted external values file (if any).

Color Relative Recurrence (%)
      0 < rr ≤ 10
      10 < rr ≤ 20
      20 < rr ≤ 30
      30 < rr ≤ 40
      40 < rr ≤ 50
      50 < rr ≤ 60
      60 < rr ≤ 70
      70 < rr ≤ 80
      80 < rr ≤ 90
      9 < rr ≤ 10

Here, those paths that begin and end at given residue pair(s) or that pass through a residue are used to generate a novel metapath. Such a path filtering is particularly recommended if some information on allosteric residues is available. The selection syntax for a residue pair ("Pairs") is C:C:c534,A:A:?600 (the lower-case "c" stands for cytosine and "?" indicates any non standard amino acid or nucleotide residue). Selection of more than one apical residue pair has the following syntax: C:C:c534,A:A:?600,C:C:c534,A:A:E41. Only one residue can be selected as a tail ("Tail"). For midway residue(s), each residue must be separated by a comma as well e.g. A:A:?600,A:A:E41.

Midway



Index Node1 Node2 Recurrency Force Hub1? Hub2? Community Value1 Value2

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrency: the relative recurrency in the filtered pool of shortest paths.

Force: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

Value1, Value2: these columns report the values present in the user submitted external values file (if any).

Download PSN data

2D representation of the global metapath and histograms of path distribution according to several parameters:

2D representation of the user filetered metapath and histograms of path distribution according to several parameters:

Net Summary
Imin 3.23
Number of Linked Nodes 352
Number of Links 411
Number of Hubs 58
Number of Links mediated by Hubs 214
Number of Communities 15
Number of Nodes involved in Communities 84
Number of Links involved in Communities 110
Path Summary
Number Of Nodes in MetaPath 97
Number Of Links MetaPath 96
Number of Shortest Paths 267734
Length Of Smallest Path 3
Average Path Length 28.4252
Length of Longest Path 56
Minimum Path Force 1.26
Average Path Force 7.15583
Maximum Path Force 17.245
Minimum Path Correlation 0.7
Average Path Correlation 0.956082
Maximum Path Correlation 1
Minimum % Of Corr. Nodes 3.0303
Average % Of Corr. Nodes 48.9551
Maximum % Of Corr. Nodes 100
Minimum Path Hubs % 0
Average Path Hubs % 38.3958
Maximum Path Hubs % 100
Filtered Path Summary
Number Of Nodes in MetaPath available after path filtering
Number Of Links MetaPath available after path filtering
Number of Shortest Paths available after path filtering
Length Of Smallest Path available after path filtering
Average Path Length available after path filtering
Length of Longest Path available after path filtering
Minimum Path Force available after path filtering
Average Path Force available after path filtering
Maximum Path Force available after path filtering
Minimum Path Correlation available after path filtering
Average Path Correlation available after path filtering
Maximum Path Correlation available after path filtering
Minimum % Of Corr. Nodes available after path filtering
Average % Of Corr. Nodes available after path filtering
Maximum % Of Corr. Nodes available after path filtering
Minimum Path Hubs % available after path filtering
Average Path Hubs % available after path filtering
Maximum Path Hubs % available after path filtering

Details about the values in these tables can be found in the corresponding documentation page .

You can download a compressed (zip) file with all submitted structures, 3D outputs (as PyMol and VMD scripts) and numerical data files (as csv and plain text files). The zip bundle also contains an output manual explaining the meaning of all files and numerical data.

Download webpsn_output_jobbL88gn.zip