psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

All columns can be sorted in ascending/descending alphabetical order, clicking on the corresponding column header.

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	2x61	NT	8.85	No	Yes	1	6	8
2	NT	NT	16.06	Yes	Yes	1	8	8
3	1x32	NT	18.55	No	Yes	0	4	8
4	1x35	NT	4.12	Yes	Yes	1	9	8
5	7x34	NT	18.95	No	Yes	0	8	8
6	1x39	NT	6.61	No	Yes	1	7	8
7	2x57	NT	6.59	No	Yes	1	9	8
8	7x37	NT	9.89	Yes	Yes	1	9	8
9	7x38	NT	4.16	No	Yes	1	8	8
10	7x42	NT	3.96	No	Yes	1	9	8
11	E2	NT	12.97	Yes	Yes	1	5	8
12	E2x51	NT	16.16	Yes	Yes	1	9	8
13	3x36	NT	8.53	No	Yes	1	8	8
14	5x43	NT	3.71	Yes	Yes	1	9	8
15	6x48	NT	6.91	Yes	Yes	1	9	8
16	5x44	NT	4.73	No	Yes	1	8	8
17	5x41	NT	6.13	No	Yes	1	8	8
18	6x55	NT	4.81	No	Yes	0	7	8
19	1x31	7x35	8.71	No	No	0	7	9
20	1x35	1x39	3	Yes	No	1	9	7
21	1x35	7x35	10.55	Yes	No	0	9	9
22	1x35	7x38	3.15	Yes	No	1	9	8
23	1x36	1x40	12.72	No	No	0	7	7
24	1x37	1x38	3.1	No	No	0	5	9
25	1x40	2x61	11.35	No	No	0	7	6
26	1x41	1x44	3.23	No	No	0	5	7
27	1x42	7x42	3.71	No	No	0	9	9
28	1x43	2x58	4.76	No	No	0	8	8
29	1x43	7x42	5.16	No	No	0	8	9
30	1x46	1x50	3	No	Yes	5	9	9
31	1x46	2x54	8.66	No	No	0	9	8
32	1x46	7x46	3.71	No	No	5	9	8
33	1x47	2x55	3.21	No	No	0	7	5
34	1x49	7x47	4.76	No	No	0	7	6
35	1x49	7x50	6.98	No	Yes	0	7	9
36	1x50	2x50	2.98	Yes	Yes	0	9	8
37	1x50	2x51	5.54	Yes	No	0	9	8
38	1x50	7x46	5.13	Yes	No	5	9	8
39	1x51	2x51	2.98	No	No	0	4	8
40	1x52	7x50	4.16	No	Yes	0	6	9
41	1x53	1x57	3.89	No	No	0	9	7
42	1x53	7x50	6.49	No	Yes	6	9	9
43	1x53	7x54	6.76	No	No	6	9	8
44	1x54	2x47	3	No	No	0	7	8
45	1x54	2x48	4.87	No	No	0	7	4
46	1x57	2x40	6.19	No	Yes	0	7	8
47	1x62	8x57	3.06	No	No	0	8	8
48	1x63	I1x49	3.17	Yes	No	0	8	9
49	1x63	I1x50	4.61	Yes	No	0	8	8
50	8x49	I1x49	4.23	No	No	0	8	9
51	2x40	I1x50	9.67	Yes	No	0	8	8
52	2x41	I1x51	4.51	No	No	0	8	7
53	2x38	4x43	14.84	No	No	0	8	7
54	2x39	2x40	4.12	Yes	Yes	3	8	8
55	2x39	3x49	5.64	Yes	No	0	8	8
56	2x39	3x53	6.2	Yes	No	3	8	8
57	2x39	8x49	5.82	Yes	No	3	8	8
58	2x40	8x47	3.49	Yes	No	3	8	9
59	2x40	8x49	11.22	Yes	No	3	8	8
60	2x40	8x50	3.79	Yes	No	3	8	9
61	2x41	4x43	3.58	No	No	0	8	7
62	2x42	3x42	4.7	Yes	Yes	2	9	9
63	2x42	3x45	6.14	Yes	Yes	2	9	8
64	2x42	3x46	5.47	Yes	Yes	0	9	9
65	2x42	4x46	4.84	Yes	Yes	2	9	8
66	2x43	3x46	19.69	No	Yes	0	9	9
67	2x43	7x53	9.55	No	Yes	0	9	9
68	2x45	3x42	16.95	No	Yes	0	9	9
69	2x45	4x47	11.63	No	No	0	9	8
70	2x46	2x50	2.98	No	Yes	0	9	8
71	2x46	3x42	4.56	No	Yes	0	9	9
72	2x46	3x46	5.3	No	Yes	0	9	9
73	2x48	2x52	7.87	No	No	0	4	6
74	2x50	2x54	5.73	Yes	No	0	8	8
75	2x52	2x56	2.98	No	No	2	6	7
76	2x52	3x35	13.11	No	Yes	2	6	8
77	2x53	3x36	8.32	No	No	0	9	8
78	2x56	3x31	4.15	No	No	2	7	7
79	2x56	3x35	3.65	No	Yes	2	7	8
80	2x57	2x61	8.53	No	No	1	9	6
81	2x57	3x32	4.15	No	No	0	9	9
82	2x60	3x28	6.13	No	No	4	8	6
83	2x60	3x32	3	No	No	0	8	9
84	2x60	E2x50	3.44	No	Yes	4	8	9
85	E1	E1	7.86	No	No	4	5	5
86	3x22	3x24	5.25	No	No	0	8	6
87	3x23	3x24	5.25	No	No	0	3	6
88	3x25	E2x50	7.28	No	Yes	4	9	9
89	3x26	E2	3.38	No	Yes	0	5	5
90	3x28	E2x50	4.86	No	Yes	4	6	9
91	3x30	E2	13.88	No	Yes	0	4	5
92	3x31	3x35	4.87	No	Yes	2	7	8
93	3x32	E2x51	3.42	No	Yes	0	9	9
94	3x33	3x37	9	Yes	Yes	1	9	9
95	3x33	4x57	4.42	Yes	No	0	9	8
96	3x33	E2	9.8	Yes	Yes	1	9	5
97	3x33	E2x51	3.17	Yes	Yes	1	9	9
98	3x33	E2x52	7.71	Yes	No	1	9	9
99	3x33	5x43	7.92	Yes	Yes	1	9	9
100	3x34	3x35	4.13	Yes	Yes	2	7	8
101	3x34	3x38	6.36	Yes	No	2	7	8
102	3x34	4x50	4.82	Yes	Yes	2	7	8
103	3x34	4x54	4.69	Yes	No	0	7	5
104	3x36	E2x51	3.01	No	Yes	1	8	9
105	3x37	4x53	3.28	Yes	Yes	0	9	8
106	3x37	5x43	6.09	Yes	Yes	1	9	9
107	3x38	4x50	7.41	No	Yes	2	8	8
108	3x38	4x53	7.13	No	Yes	0	8	8
109	3x40	5x47	8.32	No	No	0	9	9
110	3x40	5x51	5.02	No	No	0	9	9
111	3x40	6x48	18.04	No	Yes	0	9	9
112	3x41	4x53	3.74	No	Yes	0	7	8
113	3x42	3x45	7.36	Yes	Yes	2	9	8
114	3x42	4x491	11.26	Yes	No	0	9	9
115	3x42	4x50	18.74	Yes	Yes	2	9	8
116	3x43	6x45	3.49	No	No	0	9	9
117	3x43	7x45	4.08	No	No	0	9	9
118	3x44	5x50	7.45	No	No	0	9	8
119	3x45	4x46	6.31	Yes	Yes	2	8	8
120	3x45	4x49	4.56	Yes	Yes	0	8	7
121	3x46	6x43	10.93	Yes	No	0	9	8
122	3x47	5x54	3.39	No	No	0	9	9
123	3x49	4x46	9.8	No	Yes	0	8	8
124	3x50	3x54	2.98	No	No	0	9	9
125	3x50	5x61	4.47	No	No	7	9	9
126	3x50	6x40	4.15	No	Yes	7	9	9
127	3x51	3x55	13.3	No	Yes	0	8	8
128	3x51	5x57	8.46	No	No	0	8	8
129	3x53	I2	7.67	No	No	3	8	8
130	3x54	3x55	3.07	No	Yes	0	9	8
131	3x55	5x64	4.61	Yes	No	0	8	8
132	I2	I2	7.28	No	No	3	8	8
133	4x42	4x46	10.75	No	Yes	0	8	8
134	4x47	4x50	3.86	No	Yes	0	8	8
135	4x49	4x52	4.98	Yes	No	0	7	4
136	4x60	E2	6.36	No	Yes	1	8	5
137	4x64	E2	4.96	No	Yes	0	6	5
138	E2	E2	35.37	Yes	Yes	1	5	5
139	5x39	E2	5.13	No	Yes	0	7	5
140	E2	E2x52	8.21	Yes	No	1	5	9
141	E2	E2x51	5.65	Yes	Yes	1	5	9
142	E2x51	E2x52	4.56	Yes	No	1	9	9
143	5x40	E2x51	3.52	No	Yes	0	8	9
144	5x43	E2x51	5.01	Yes	Yes	1	9	9
145	5x41	5x44	7.36	No	No	1	8	8
146	5x48	5x52	2.98	No	No	0	7	4
147	5x49	5x53	3.93	No	No	0	5	8
148	5x51	6x49	4.61	No	No	0	9	5
149	5x54	6x44	13.73	No	No	0	9	9
150	5x55	5x56	3.53	No	No	0	5	5
151	5x55	6x46	4.56	No	No	0	5	8
152	5x58	6x40	4.15	No	Yes	0	8	9
153	5x58	6x44	5.54	No	No	0	8	9
154	5x61	5x65	3.07	No	Yes	0	9	9
155	5x61	6x40	2.98	No	Yes	7	9	9
156	5x65	6x36	3.25	Yes	No	0	9	9
157	5x66	6x33	3.2	No	Yes	0	8	8
158	5x69	6x33	3.2	No	Yes	0	8	8
159	5x71	5x74	6.91	No	No	0	6	6
160	5x73	I3	4.35	No	No	0	6	6
161	6x26	6x27	8.05	No	No	0	6	5
162	6x26	6x28	5.89	No	No	0	6	6
163	6x28	6x31	3.06	No	No	0	6	6
164	6x39	7x52	6.55	No	No	0	8	8
165	6x43	7x53	3.98	No	Yes	0	8	9
166	6x47	7x40	6.01	No	No	0	9	6
167	6x47	7x41	4.47	No	No	0	9	9
168	6x48	7x37	8.02	Yes	Yes	1	9	9
169	6x48	7x41	24.86	Yes	No	1	9	9
170	6x48	7x45	4.38	Yes	No	0	9	9
171	6x50	7x37	3.22	No	Yes	0	8	9
172	6x51	7x37	6.02	No	Yes	0	9	9
173	6x53	7x33	4.87	No	No	0	7	7
174	E3	E3	5.09	No	No	8	5	5
175	7x33	E3	3.62	No	No	8	7	5
176	7x31	7x35	6.31	No	No	0	5	9
177	7x32	7x36	4.56	No	No	0	5	5
178	7x37	7x41	12.08	Yes	No	1	9	9
179	7x43	7x48	6.09	No	No	0	7	8
180	7x49	7x53	6.63	No	Yes	0	8	9
181	7x50	7x54	4.19	Yes	No	6	9	8
182	7x50	7x55	9.74	Yes	No	0	9	7
183	7x51	7x52	4.87	No	No	0	8	8
184	7x51	7x56	5.54	No	No	0	8	8
185	8x47	8x50	7.39	No	No	3	9	9
186	8x54	8x58	3.89	No	No	0	7	8
187	7x39	7x40	2.95	No	No	0	5	6
188	7x39	7x43	2.95	No	No	0	5	7
189	5x51	5x55	2.94	No	No	0	9	5
190	1x28	1x31	2.93	No	No	0	3	7
191	6x42	7x48	2.89	No	No	0	9	8
192	1x47	2x54	2.87	No	No	0	7	8
193	1x35	1x38	2.85	Yes	No	0	9	9
194	1x60	I1x50	2.85	No	No	0	8	8
195	6x40	6x43	2.85	Yes	No	0	9	8
196	3x44	4x49	2.83	No	Yes	0	9	7
197	3x48	4x49	2.83	No	Yes	0	7	7
198	1x57	2x44	2.77	No	No	0	7	7
199	5x60	5x63	2.77	No	No	0	8	7
200	3x29	E2	2.67	No	Yes	0	9	5
201	4x62	4x63	2.64	No	No	0	6	5
202	8x48	8x51	2.64	No	No	0	8	9
203	7x32	7x33	2.62	No	No	0	5	7
204	6x50	7x36	2.49	No	No	0	8	5
205	1x60	8x54	2.44	No	No	0	8	7
206	4x61	E2	2.34	No	Yes	1	4	5
207	2x37	2x40	2.33	No	Yes	0	8	8
208	7x52	7x53	2.26	No	Yes	0	8	9
209	2x38	4x46	2.25	No	Yes	0	8	8
210	4x51	4x53	2.03	No	Yes	0	9	8
211	5x45	5x46	1.87	No	No	0	7	9
212	1x30	1x33	1.84	No	No	0	2	5
213	1x41	1x42	1.84	No	No	0	5	9
214	2x49	3x39	1.79	No	No	0	8	7
215	4x60	5x42	1.71	No	No	0	8	9
216	5x69	6x29	1.71	No	No	0	8	8
217	7x29	7x32	1.71	No	No	0	4	5
218	6x54	NT	1.7	No	Yes	0	8	8
219	1x63	8x53	1.7	Yes	No	0	8	8
220	2x50	3x39	1.7	Yes	No	0	8	7
221	3x22	3x25	1.69	No	No	4	8	9
222	3x37	5x46	1.64	Yes	No	0	9	9
223	6x41	6x42	1.64	No	No	0	8	9
224	1x62	1x63	1.62	No	Yes	0	8	8
225	3x55	5x60	1.62	Yes	No	0	8	8
226	1x51	1x55	1.6	No	No	0	4	6
227	1x55	1x56	1.59	No	No	0	6	8
228	2x63	3x25	1.59	No	No	4	4	9
229	2x63	E2x50	1.59	No	Yes	4	4	9
230	5x62	6x37	1.59	No	No	0	9	8
231	7x30	NT	1.58	No	Yes	0	6	8
232	5x62	6x33	1.57	No	Yes	0	9	8
233	2x55	2x59	1.54	No	No	0	5	4
234	5x53	5x57	1.54	No	No	0	8	8
235	6x26	6x29	1.54	No	No	0	6	8
236	3x52	3x56	1.53	No	No	0	8	7
237	6x52	NT	1.52	No	Yes	1	7	8
238	5x65	6x33	1.52	Yes	Yes	0	9	8
239	1x29	1x30	1.5	No	No	0	1	2
240	1x44	1x45	1.5	No	No	0	7	5
241	8x55	8x58	1.5	No	No	0	8	8
242	1x47	1x48	1.49	No	No	0	7	4
243	1x59	1x60	1.49	No	No	0	4	8
244	5x48	6x49	1.49	No	No	0	7	5
245	5x48	6x52	1.49	No	No	0	7	7
246	5x66	5x67	1.44	No	No	0	8	8
247	3x37	4x56	1.43	Yes	No	0	9	7
248	4x54	4x58	1.43	No	No	0	5	4
249	4x58	4x61	1.43	No	No	0	4	4
250	5x65	6x32	1.43	Yes	No	0	9	8
251	5x72	I3	1.42	No	No	0	6	6
252	3x22	E1	1.41	No	No	4	8	5
253	6x35	7x56	1.41	No	No	0	9	8
254	1x63	8x56	1.38	Yes	No	0	8	8
255	5x71	5x72	1.35	No	No	0	6	6
256	4x59	4x63	1.26	No	No	0	6	5
257	5x59	5x63	1.25	No	No	0	4	7
258	8x51	8x55	1.24	No	No	0	9	8

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

All columns can be sorted in ascending/descending alphabetical order, clicking on the corresponding column header.

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg. Int. Strength	Num. Of Links	Community	ConSurf
1	NT	8.29773	22	1	8
2	1x35	4.734	5	1	9
3	1x50	4.1625	4	5	9
4	1x63	2.496	5	0	8
5	2x39	5.445	4	3	8
6	2x40	5.83	7	3	8
7	2x42	5.2875	4	2	9
8	2x50	3.3475	4	0	8
9	3x33	7.00333	6	1	9
10	3x34	5	4	2	7
11	3x35	6.44	4	2	8
12	3x37	4.288	5	1	9
13	3x42	10.595	6	2	9
14	3x45	6.0925	4	2	8
15	3x46	10.3475	4	0	9
16	3x55	5.65	4	0	8
17	4x46	6.79	5	2	8
18	4x49	3.8	4	0	7
19	4x50	8.7075	4	2	8
20	4x53	4.045	4	0	8
21	E2	11.2377	13	1	5
22	E2x50	4.2925	4	4	9
23	E2x51	5.5625	8	1	9
24	5x43	5.6825	4	1	9
25	5x65	2.3175	4	0	9
26	6x33	2.3725	4	0	8
27	6x40	3.5325	4	7	9
28	6x48	12.442	5	1	9
29	7x37	7.846	5	1	9
30	7x50	6.312	5	6	9
31	7x53	5.605	4	0	9

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

All columns can be sorted in ascending/descending alphabetical order, clicking on the corresponding column header.

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	2x46	2x50	18.9245	2.98	No	Yes	0	9	8
2	2x46	3x42	37.9752	4.56	No	Yes	0	9	9
3	3x42	4x50	100	18.74	Yes	Yes	2	9	8
4	3x38	4x50	86.1394	7.41	No	Yes	2	8	8
5	3x38	4x53	88.8805	7.13	No	Yes	0	8	8
6	3x37	4x53	87.7011	3.28	Yes	Yes	0	9	8
7	3x37	5x43	66.5585	6.09	Yes	Yes	1	9	9
8	5x43	NT	55.3271	3.71	Yes	Yes	1	9	8
9	1x53	1x57	10.3765	3.89	No	No	0	9	7
10	1x57	2x40	13.3485	6.19	No	Yes	0	7	8
11	2x39	2x40	36.2728	4.12	Yes	Yes	3	8	8
12	2x39	3x49	49.5059	5.64	Yes	No	0	8	8
13	3x49	4x46	50.7286	9.8	No	Yes	0	8	8
14	2x42	4x46	33.6832	4.84	Yes	Yes	2	9	8
15	2x42	3x42	47.8143	4.7	Yes	Yes	2	9	9
16	3x45	4x46	24.5798	6.31	Yes	Yes	2	8	8
17	3x42	3x45	27.0901	7.36	Yes	Yes	2	9	8
18	3x34	3x35	10.2395	4.13	Yes	Yes	2	7	8
19	3x34	4x54	10.7192	4.69	Yes	No	0	7	5
20	4x54	4x58	10.2503	1.43	No	No	0	5	4
21	2x40	I1x50	18.8632	9.67	Yes	No	0	8	8
22	2x42	3x46	34.5488	5.47	Yes	Yes	0	9	9
23	2x46	3x46	29.2072	5.3	No	Yes	0	9	9
24	2x60	3x32	19.552	3	No	No	0	8	9
25	2x60	E2x50	15.5233	3.44	No	Yes	4	8	9
26	3x25	E2x50	11.1231	7.28	No	Yes	4	9	9
27	3x33	E2x51	11.7146	3.17	Yes	Yes	1	9	9
28	6x48	NT	19.9271	6.91	Yes	Yes	1	9	8
29	3x46	6x43	47.8901	10.93	Yes	No	0	9	8
30	6x40	6x43	39.1005	2.85	Yes	No	0	9	8
31	3x50	6x40	14.0879	4.15	No	Yes	7	9	9
32	3x50	3x54	13.3413	2.98	No	No	0	9	9
33	3x54	3x55	11.9924	3.07	No	Yes	0	9	8
34	5x61	6x40	18.9281	2.98	No	Yes	7	9	9
35	5x61	5x65	18.4231	3.07	No	Yes	0	9	9
36	5x65	6x33	14.8886	1.52	Yes	Yes	0	9	8
37	7x52	7x53	12.6416	2.26	No	Yes	0	8	9
38	7x37	NT	18.8379	9.89	Yes	Yes	1	9	8
39	6x47	7x41	16.2303	4.47	No	No	0	9	9
40	6x47	7x40	13.9328	6.01	No	No	0	9	6
41	7x39	7x40	11.6281	2.95	No	No	0	5	6
42	1x60	I1x50	10.6254	2.85	No	No	0	8	8
43	3x32	E2x51	19.1048	3.42	No	Yes	0	9	9
44	5x43	E2x51	11.2638	5.01	Yes	Yes	1	9	9
45	3x34	4x50	13.8065	4.82	Yes	Yes	2	7	8
46	3x33	3x37	19.397	9	Yes	Yes	1	9	9

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

there is no ligand in network adgrd_on

Consensus Members
	Id	Members
	adgrd1_on	7WU2-ADGRD1-Gs/β1/γ1

Net Summary
I_min	2.98
Number of Linked Nodes	224
Number of Links	258
Number of Hubs	31
Number of Links mediated by Hubs	139
Number of Communities	8
Number of Nodes involved in Communities	58
Number of Links involved in Communities	81

Path Summary
Number Of Nodes in MetaPath	47
Number Of Links MetaPath	46
Number of Shortest Paths	43643
Length Of Smallest Path	3
Average Path Length	13.3341
Length of Longest Path	28
Minimum Path Strength	1.37
Average Path Strength	6.23807
Maximum Path Strength	21.45
Minimum Path Correlation	0.7
Average Path Correlation	0.91763
Maximum Path Correlation	0.99
Minimum % Of Corr. Nodes	5.26316
Average % Of Corr. Nodes	43.4609
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	53.5373
Maximum Path Hubs %	100

Details about the values in these tables can be found in the corresponding documentation page .

This network is also present in following consensuses:
	Id	Components
	class-b2_on	adgrg_on adgrf_on adgrl_on adgre_on adgrd_on

there is no ligand in network adgrd_on

Data downloads are temporarily suspended for technical reasons. We apologize for the inconvenience.

Data downloads are temporarily suspended for technical reasons.
We apologize for the inconvenience.