Orange: nodes, hubs and links specific of 5ht1_on_gp network

Green: nodes, hubs and links shared by both networks

Purple: nodes, hubs and links specific of 5ht1_off network

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Owner: the name of the network the hub belong to or "Shared" if the corresponding hub is present in both networks.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub in the corresponding network.

Num Of Links: the number of links of the corresponding hub in the corresponding network.

ConSurf: this column reports the ConSurf conservation grades of each hub.


Index Hub Owner 5ht1_on_gp Avg Int. Strength 5ht1_off Avg Int. Strength 5ht1_on_gp Num Of Links 5ht1_off Num Of Links ConSurf
1G.HN.11 5ht1_on_gp2.61410402
2G.S1.02 5ht1_on_gp4.620440505
3G.H1.01 5ht1_on_gp4.27450509
4G.H1.04 5ht1_on_gp4.620409
5G.S2.03 5ht1_on_gp4.5550405
6G.S2.06 5ht1_on_gp4.945620403
7G.S2.08 5ht1_on_gp8.320630403
8G.S3.01 5ht1_on_gp4.725110503
9G.S3.03 5ht1_on_gp7.202720504
10G.S3.04 5ht1_on_gp7.460210407
11G.S3.06 5ht1_on_gp8.463390507
12G.s3h2.03 5ht1_on_gp4.497430409
13G.H2.02 5ht1_on_gp4.634380409
14G.H2.03 5ht1_on_gp5.026830508
15G.H2.04 5ht1_on_gp3.864560509
16G.H2.06 5ht1_on_gp5.45190708
17G.H2.07 5ht1_on_gp4.859330709
18G.H2.09 5ht1_on_gp6.472150408
19G.h2s4.01 5ht1_on_gp7.764280507
20G.S4.04 5ht1_on_gp7.341390407
21G.s4h3.04 5ht1_on_gp5.459920708
22G.H3.01 5ht1_on_gp4.511940409
23G.H3.09 5ht1_on_gp5.995440709
24G.H3.17 5ht1_on_gp7.708660604
25G.H3.18 5ht1_on_gp5.364440505
26G.S5.03 5ht1_on_gp3.262830506
27G.S5.04 5ht1_on_gp4.214830508
28G.S5.05 5ht1_on_gp3.959370709
29G.HG.01 5ht1_on_gp3.778820409
30G.HG.04 5ht1_on_gp6.360760406
31G.HG.13 5ht1_on_gp3.277920401
32G.hgh4.02 5ht1_on_gp7.008820406
33G.hgh4.05 5ht1_on_gp7.856460406
34G.H4.10 5ht1_on_gp8.248680403
35G.H4.14 5ht1_on_gp6.222570403
36G.H4.15 5ht1_on_gp4.335930605
37G.H4.16 5ht1_on_gp5.677920408
38G.h4s6.11 5ht1_on_gp3.838960403
39G.S6.02 5ht1_on_gp5.676940705
40G.S6.05 5ht1_on_gp4.666670409
41G.s6h5.01 5ht1_on_gp5.998750404
42G.H5.08 5ht1_on_gp5.911830508
43G.H5.17 5ht1_on_gp6.047640406
44G.H5.20 5ht1_on_gp4.293890408
45G.H5.25 5ht1_on_gp3.560508
46G.H5.26 5ht1_on_gp8.632780407
47b.1x4 5ht1_on_gp2.296740408
48b.lhb1x3 5ht1_on_gp2.789650402
49b.lhb1x6 5ht1_on_gp3.871040403
50b.b1x6 5ht1_on_gp7.06090409
51b.l1x3 5ht1_on_gp8.653610609
52b.b2x1 5ht1_on_gp8.386810608
53b.b2x5 5ht1_on_gp8.004610507
54b.b3x3 5ht1_on_gp3.5160508
55b.l3x2 5ht1_on_gp5.154560509
56b.b4x3 5ht1_on_gp4.809860407
57b.b4x4 5ht1_on_gp9.630408
58b.b4x6 5ht1_on_gp10.66870609
59b.l4x2 5ht1_on_gp11.07640404
60b.b5x2 5ht1_on_gp6.208610407
61b.b5x3 5ht1_on_gp6.790560609
62b.b5x5 5ht1_on_gp5.768190405
63b.b5x7 5ht1_on_gp6.734030407
64b.l5x1 5ht1_on_gp4.962170508
65b.l5x5 5ht1_on_gp7.738680809
66b.b6x5 5ht1_on_gp4.036940706
67b.l6x5 5ht1_on_gp5.918060404
68b.b7x1 5ht1_on_gp6.391110404
69b.b7x4 5ht1_on_gp4.286670408
70b.l7x4 5ht1_on_gp4.392360409
71b.l7x5 5ht1_on_gp3.577640406
72b.b8x3 5ht1_on_gp3.69160406
73b.b8x4 5ht1_on_gp5.920170506
74b.b9x3 5ht1_on_gp4.883780506
75b.l9x3 5ht1_on_gp7.570509
76b.l9x6 5ht1_on_gp6.344210608
77b.b10x4 5ht1_on_gp5.436670406
78b.b10x5 5ht1_on_gp5.333670509
79b.l10x1 5ht1_on_gp5.065420403
80b.b11x4 5ht1_on_gp5.675620409
81b.b11x5 5ht1_on_gp4.590690406
82b.l11x2 5ht1_on_gp6.427920409
83b.b12x3 5ht1_on_gp3.622010408
84b.b12x6 5ht1_on_gp8.450090608
85b.b12x7 5ht1_on_gp5.276810409
86b.b13x7 5ht1_on_gp7.765940507
87b.l13x3 5ht1_on_gp7.840090609
88b.l13x6 5ht1_on_gp5.469280509
89b.l13x7 5ht1_on_gp4.679030409
90b.b14x3 5ht1_on_gp5.052850405
91b.b15x1 5ht1_on_gp7.889790409
92b.b15x3 5ht1_on_gp4.462290409
93b.l15x1 5ht1_on_gp5.999580407
94b.l15x2 5ht1_on_gp5.5120509
95b.b16x4 5ht1_on_gp10.03290406
96b.b16x5 5ht1_on_gp5.679440405
97b.b16x6 5ht1_on_gp8.945370608
98b.b17x5 5ht1_on_gp7.70090407
99b.b17x7 5ht1_on_gp9.02410408
100b.l17x3 5ht1_on_gp8.138810709
101b.l17x6 5ht1_on_gp6.752290409
102b.b18x3 5ht1_on_gp5.997710408
103b.b18x5 5ht1_on_gp6.147780405
104b.l18x1 5ht1_on_gp6.263020706
105b.l18x2 5ht1_on_gp6.178260407
106b.b19x2 5ht1_on_gp7.315970606
107b.b19x4 5ht1_on_gp5.788280508
108b.l19x1 5ht1_on_gp5.734440409
109b.l19x2 5ht1_on_gp6.239390509
110b.b20x4 5ht1_on_gp8.026620608
111b.b20x6 5ht1_on_gp7.118430606
112b.b20x7 5ht1_on_gp4.959650409
113b.l20x2 5ht1_on_gp8.819860409
114b.b21x1 5ht1_on_gp6.700140607
115b.b21x5 5ht1_on_gp5.318820404
116b.b21x7 5ht1_on_gp5.280320605
117b.l21x7 5ht1_on_gp3.565350405
118b.b22x5 5ht1_on_gp6.719370407
119b.l22x5 5ht1_on_gp6.201440609
120b.b23x6 5ht1_on_gp6.786530607
121b.l23x1 5ht1_on_gp7.689790406
122b.b24x4 5ht1_on_gp7.210110506
123b.b24x6 5ht1_on_gp5.89660408
124b.l24x3 5ht1_on_gp4.325690405
125b.b25x3 5ht1_on_gp6.455070405
126b.l25x3 5ht1_on_gp8.083280509
127b.l25x6 5ht1_on_gp12.58780408
128b.l26x1 5ht1_on_gp6.555350407
129b.l27x1 5ht1_on_gp11.48650709
130b.l27x2 5ht1_on_gp7.352220409
131b.b28x2 5ht1_on_gp6.5350404
132b.b28x3 5ht1_on_gp4.233190407
133b.b28x4 5ht1_on_gp8.600630406
134b.b28x6 5ht1_on_gp8.638670509
135g.h1x5 5ht1_on_gp2.280210406
136g.l1x4 5ht1_on_gp4.580210408
137g.h2x11 5ht1_on_gp9.514790406
138g.ctx3 5ht1_on_gp6.799170509
139g.ctx5 5ht1_on_gp3.745350409
140g.ctx6 5ht1_on_gp3.48120606
141g.ctx14 5ht1_on_gp4.79050509
142g.ctx15 5ht1_on_gp8.060490409
143g.ctx16 5ht1_on_gp5.320240808
1441x39 5ht1_on_gp6.3094416.045427
145I1x50 5ht1_on_gp6.371187.195428
1462x46 5ht1_on_gp4.790894.11529
1473x43 5ht1_on_gp6.073473.55438
1483x50 5ht1_on_gp7.221944.69439
149I2x51 5ht1_on_gp3.780690406
150I2x57 5ht1_on_gp8.3619510.8433438
1515x39 5ht1_on_gp4.887575.56418
1525x66 5ht1_on_gp5.264388.08437
1535x68 5ht1_on_gp3.939176.575427
1546x36 5ht1_on_gp4.455147.99418
1556x37 5ht1_on_gp3.072781.43418
1566x54 5ht1_on_gp3.77254.25667436
157E3 5ht1_on_gp4.211620604
1587x49 5ht1_on_gp7.3326710.175529
1597x53 5ht1_on_gp5.2132411.735629
1608x49 5ht1_on_gp4.309797.42427
1618x54 5ht1_on_gp4.189513.07438
162I3 5ht1_on_gp3.61250800
163Lig Shared7.756997.3015412130
1642x50 Shared5.845445.86559
1652x56 Shared4.471396.9775448
1662x57 Shared4.102877.4875648
167E1x50 Shared7.385058.41429679
1683x32 Shared8.4213210.2725448
1693x41 Shared6.078898.09457
1703x42 Shared6.742559.022658
1713x51 Shared7.564786.11549
172I2x53 Shared8.7477211.294558
173E2 Shared6.450819.831154
1745x47 Shared8.4973211.954658
1755x48 Shared4.590426.956457
1765x58 Shared5.149314.07659
1776x44 Shared4.709776.474659
1786x48 Shared6.190598.05143978
1796x51 Shared5.606769.238658
1806x52 Shared9.8621513.994457
1817x37 Shared3.839176.2575446
1827x39 Shared6.354449.18714778
1837x42 Shared6.168156.35678
1847x52 Shared3.279332.694558
1858x50 Shared6.808535.115748
186NT 5ht1_off1.2417.6217160
1871x52 5ht1_off1.869914.5425348
1883x28 5ht1_off8.204177.76356
1893x40 5ht1_off5.018156.23348
1903x49 5ht1_off7.251397.785349
1913x52 5ht1_off8.4519411.175345
1924x50 5ht1_off6.727416.205349
1935x62 5ht1_off5.061114.3675346
1945x64 5ht1_off1.625.5475146
1956x31 5ht1_off1.157086.37246
1966x41 5ht1_off3.791113.7725248
1976x49 5ht1_off4.211574.5875347
1986x58 5ht1_off5.300565.285244
1997x45 5ht1_off9.496948.73349
2007x48 5ht1_off3.548613.6725246
   
Orange: nodes, hubs and links specific of 5ht1_on_gp network

Green: nodes, hubs and links shared by both networks

Purple: nodes, hubs and links specific of 5ht1_off network

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Owner: the name of the network the link belong to or "Shared" if the corresponding link is present in both networks.

Recurrence: the relative Recurrence in the filtered pool of shortest paths.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.


Index Node1 Node2 Owner 5ht1_on_gp Recurrence 5ht1_off Recurrence 5ht1_on_gp Hub1? 5ht1_off Hub1? 5ht1_on_gp Hub2? 5ht1_off Hub2? ConSurf1 ConSurf2
1b.l2x3 b.l2x5 5ht1_on_gp16.40070NoNoNoNo85
2b.b3x1 b.l2x3 5ht1_on_gp16.54280NoNoNoNo58
3b.b3x1 b.b6x5 5ht1_on_gp16.68620NoNoYesNo56
4b.b2x4 b.b6x5 5ht1_on_gp33.04990NoNoYesNo66
5b.b10x4 b.b2x4 5ht1_on_gp33.16960YesNoNoNo66
6b.b10x2 b.b10x4 5ht1_on_gp33.6610NoNoYesNo66
7b.b10x2 b.b14x3 5ht1_on_gp32.64360NoNoYesNo65
8b.b11x5 b.b14x3 5ht1_on_gp32.9450YesNoYesNo65
9b.b10x1 b.b11x5 5ht1_on_gp40.03220NoNoYesNo96
10b.b10x1 b.b14x1 5ht1_on_gp40.16140NoNoNoNo98
11b.b14x1 b.l9x6 5ht1_on_gp54.89770NoNoYesNo88
12G.H2.07 b.l9x6 5ht1_on_gp62.33280YesNoYesNo98
13G.H2.04 G.H2.07 5ht1_on_gp67.4580YesNoYesNo99
14G.H2.04 G.H3.08 5ht1_on_gp99.9270YesNoNoNo95
15G.H3.08 G.S4.04 5ht1_on_gp1000NoNoYesNo57
16G.H3.09 G.S4.04 5ht1_on_gp33.90020YesNoYesNo97
17G.H3.09 G.S6.01 5ht1_on_gp29.07460YesNoNoNo94
18G.H4.16 G.S6.01 5ht1_on_gp28.89920YesNoNoNo84
19G.H4.16 I3 5ht1_on_gp57.66810YesNoYesNo80
20G.h4s6.12 I3 5ht1_on_gp88.14150NoNoYesNo70
21G.S6.02 G.h4s6.12 5ht1_on_gp87.97080YesNoNoNo57
22G.S5.03 G.S6.02 5ht1_on_gp31.75070YesNoYesNo65
23G.S4.03 G.S5.03 5ht1_on_gp25.69690NoNoYesNo86
24G.S1.04 G.S4.03 5ht1_on_gp25.56650NoNoNoNo78
25G.S1.02 G.S1.04 5ht1_on_gp10.58970YesNoNoNo57
26G.S4.04 G.S5.04 5ht1_on_gp61.840YesNoYesNo78
27G.S5.04 G.S6.03 5ht1_on_gp29.12020YesNoNoNo87
28G.H4.16 G.S6.03 5ht1_on_gp28.66610YesNoNoNo87
29G.S5.04 G.S5.06 5ht1_on_gp29.5080YesNoNoNo89
30G.S5.06 G.S6.05 5ht1_on_gp30.83550NoNoYesNo99
31G.S6.05 I3 5ht1_on_gp30.53990YesNoYesNo90
32G.S1.04 G.S3.03 5ht1_on_gp14.75060NoNoYesNo74
33G.S3.01 I2x51 5ht1_on_gp13.75130YesNoYesNo36
34G.H2.06 b.b14x1 5ht1_on_gp23.53570YesNoNoNo88
35G.H2.06 b.l19x1 5ht1_on_gp23.7940YesNoYesNo89
36G.H2.04 G.H2.08 5ht1_on_gp36.5010YesNoNoNo99
37G.H3.15 G.H3.17 5ht1_on_gp35.85210NoNoYesNo84
38G.H2.08 G.H3.15 5ht1_on_gp35.86650NoNoNoNo98
39G.H3.17 b.l25x6 5ht1_on_gp33.80440YesNoYesNo48
40b.l2x5 b.l4x2 5ht1_on_gp13.40690NoNoYesNo54
41g.ctx3 g.ctx6 5ht1_on_gp22.31490YesNoYesNo96
42b.l22x5 g.ctx6 5ht1_on_gp23.04310YesNoYesNo96
43b.l22x5 b.l24x2 5ht1_on_gp24.91120YesNoNoNo96
44b.h2x5 b.l24x2 5ht1_on_gp25.20050NoNoNoNo56
45b.h2x1 b.h2x5 5ht1_on_gp25.33280NoNoNoNo55
46b.b21x5 b.h2x1 5ht1_on_gp24.83410YesNoNoNo45
47b.b21x5 b.b21x7 5ht1_on_gp25.2460YesNoYesNo45
48b.b21x7 b.b24x6 5ht1_on_gp30.81340YesNoYesNo58
49b.b23x6 b.b24x6 5ht1_on_gp31.07370YesNoYesNo78
50b.b23x6 b.l21x7 5ht1_on_gp33.71780YesNoYesNo75
51b.l21x7 b.l23x1 5ht1_on_gp34.67490YesNoYesNo56
52b.l23x1 b.l25x6 5ht1_on_gp34.9350YesNoYesNo68
53G.H5.17 G.S6.02 5ht1_on_gp60.75570YesNoYesNo65
54G.H5.17 G.H5.26 5ht1_on_gp59.62070YesNoYesNo67
553x51 3x55 5ht1_on_gp11.42747.7879YesYesNoNo98
563x55 3x56 5ht1_on_gp11.90140NoNoNoNo87
573x56 I2x52 5ht1_on_gp12.37521.41873NoNoNoNo76
58I2x51 I2x52 5ht1_on_gp12.84880YesNoNoNo66
59G.H5.20 G.H5.26 5ht1_on_gp57.66960YesNoYesNo87
60G.H5.20 G.H5.25 5ht1_on_gp56.86850YesNoYesNo88
61G.H5.23 G.H5.25 5ht1_on_gp11.63350NoNoYesNo48
623x50 G.H5.23 5ht1_on_gp11.45290YesNoNoNo94
636x37 G.H5.25 5ht1_on_gp43.82930YesNoYesNo88
64b.l17x5 b.l19x1 5ht1_on_gp24.67960NoNoYesNo69
65b.l17x5 b.l19x2 5ht1_on_gp24.47970NoNoYesNo69
66b.l17x3 b.l19x2 5ht1_on_gp22.60820YesNoYesNo99
67b.b20x6 b.l17x3 5ht1_on_gp15.27380YesNoYesNo69
68b.b17x7 b.b20x6 5ht1_on_gp12.16970YesNoYesNo86
69b.b17x7 b.b21x1 5ht1_on_gp10.12750YesNoYesNo87
70g.ctx3 g.ctx5 5ht1_on_gp23.96480YesNoYesNo99
71b.lhb1x11 g.ctx5 5ht1_on_gp22.6460NoNoYesNo49
72b.b28x6 b.lhb1x11 5ht1_on_gp22.07810YesNoNoNo94
73b.b28x4 b.b28x6 5ht1_on_gp11.72640YesNoYesNo69
74b.b27x3 b.b28x6 5ht1_on_gp10.00020NoNoYesNo89
75b.l25x3 b.l27x2 5ht1_on_gp17.35950YesNoYesNo99
76b.b3x3 b.b6x5 5ht1_on_gp19.2370YesNoYesNo86
77b.b3x3 b.b4x3 5ht1_on_gp12.38320YesNoYesNo87
78b.l25x4 b.l27x2 5ht1_on_gp13.54760NoNoYesNo59
798x56 b.l25x4 5ht1_on_gp13.16210NoNoNoNo65
806x48 Lig 5ht1_on_gp17.28853.13428YesYesYesYes80
816x44 6x48 5ht1_on_gp31.14450YesYesYesYes98
825x54 6x44 5ht1_on_gp36.89780NoNoYesYes99
835x54 5x58 5ht1_on_gp37.10710NoNoYesYes99
845x58 6x37 5ht1_on_gp40.25380YesYesYesNo98
856x48 6x51 5ht1_on_gp10.20348.33124YesYesYesYes88
861x60 I1x50 5ht1_on_gp12.02553.2852NoNoYesNo78
871x60 8x56 5ht1_on_gp12.79710NoNoNoNo76
881x29 1x32 5ht1_off010.8065NoNoNoNo04
891x32 2x65 5ht1_off1.940120.7929NoNoNoNo46
901x36 2x65 5ht1_off0.24877125.0641NoNoNoNo56
911x36 2x61 5ht1_off026.4778NoNoNoNo57
922x61 7x39 5ht1_off0.24456227.6299NoNoYesYes78
932x57 7x39 5ht1_off0.0083303716.3405YesYesYesYes88
941x46 2x57 5ht1_off0.73465113.7546NoNoYesYes88
951x50 2x50 5ht1_off1.8964314.3633NoNoYesYes99
967x53 8x50 5ht1_off030.1555YesNoYesYes98
972x43 7x53 5ht1_off031.378NoNoYesNo89
982x40 2x43 5ht1_off032.842NoNoNoNo98
992x37 2x40 5ht1_off0.39117737.0982NoNoNoNo89
1002x37 2x39 5ht1_off038.4968NoNoNoNo88
1012x39 3x50 5ht1_off039.6639NoNoYesNo89
1023x49 3x50 5ht1_off042.436NoYesYesNo99
1033x49 I2x53 5ht1_off1.4322145.7816NoYesYesYes98
1043x52 I2x53 5ht1_off7.1539563.1886NoYesYesYes58
1053x51 3x52 5ht1_off8.1032668.1139YesYesNoYes95
1063x51 5x57 5ht1_off0.95448579.7957YesYesNoNo97
1075x53 5x57 5ht1_off081.9238NoNoNoNo77
1083x44 5x53 5ht1_off0.47079882.9401NoNoNoNo77
1093x41 3x44 5ht1_off0.941508100YesYesNoNo77
1103x41 5x50 5ht1_off1.7138688.7609YesYesNoNo79
1113x40 5x50 5ht1_off2.4407190.2048NoYesNoNo89
1123x40 Lig 5ht1_off073.4668NoYesYesYes80
1137x42 Lig 5ht1_off8.4080764.7432YesYesYesYes80
1147x39 7x42 5ht1_off2.6765936.9472YesYesYesYes88
1157x54 8x50 5ht1_off1.1705515.1381NoNoYesYes88
1167x54 8x54 5ht1_off0.0033321510.6404NoNoYesNo88
1172x38 I2x57 5ht1_off0.47825114.2677NoNoYesNo78
118I2x53 I2x57 5ht1_off1.4330914.1772YesYesYesNo88
1193x38 4x53 5ht1_off022.2871NoNoNoNo88
1203x37 4x53 5ht1_off0.24991127.1721NoNoNoNo88
1213x37 Lig 5ht1_off1.4972829.5266NoNoYesYes80
1223x42 4x50 5ht1_off013.4829YesYesNoYes89
1233x38 4x50 5ht1_off0.51341412.7232NoNoNoYes89
1243x42 4x49 5ht1_off1.8368922.4631YesYesNoNo88
1253x41 4x49 5ht1_off1.6205625.7383YesYesNoNo78
1263x43 6x44 5ht1_off0.38766921.5727YesNoYesYes89
1273x40 6x44 5ht1_off2.5209527.0614NoYesYesYes89
1286x44 7x45 5ht1_off011.8328YesYesNoYes99
1296x48 7x42 5ht1_off015.8223YesYesYesYes88
1307x45 7x49 5ht1_off0.88345810.5046NoYesYesNo99
1312x56 7x42 5ht1_off3.4614925.8641YesYesYesYes88
1322x60 3x28 5ht1_off026.1659NoNoNoYes76
133E1x50 E1x52 5ht1_off2.1536211.4504YesYesNoNo97
1343x28 E1x50 5ht1_off5.8661654.7869NoYesYesYes69
1352x63 E1x50 5ht1_off0.89608525.4465NoNoYesYes69
1362x63 E2 5ht1_off0.1862521.6632NoNoYesYes64
1373x30 4x61 5ht1_off015.928NoNoNoNo76
1383x30 4x57 5ht1_off0.74964618.2623NoNoNoNo78
1393x34 4x57 5ht1_off0.4999120.5816NoNoNoNo68
1403x34 4x53 5ht1_off029.758NoNoNoNo68
1413x40 5x47 5ht1_off011.5762NoYesYesYes88
1423x44 5x54 5ht1_off027.4689NoNoNoNo79
1434x63 E2 5ht1_off014.8715NoNoYesYes54
1444x63 5x36 5ht1_off0.24877111.4605NoNoNoNo56
1455x54 6x41 5ht1_off025.9898NoNoNoYes98
1465x58 6x41 5ht1_off0.69641919.9477YesYesNoYes98
1475x58 5x62 5ht1_off013.9961YesYesNoYes96
1483x43 6x40 5ht1_off014.2476YesNoNoNo88
1496x51 Lig 5ht1_off0.15529617.7341YesYesYesYes80
1506x54 7x34 5ht1_off0.24649115.118YesNoNoNo64
1516x51 7x34 5ht1_off029.8536YesYesNoNo84
1526x58 7x34 5ht1_off013.1358NoYesNoNo44
1532x56 3x28 5ht1_off7.2895242.9642YesYesNoYes86
1542x56 3x32 5ht1_off6.6753519.4144YesYesYesYes88
1556x40 7x52 5ht1_off1.8062910.6153NoNoYesYes88
1562x60 7x42 5ht1_off0.24394823.3083NoNoYesYes78
1573x32 Lig 5ht1_off3.6292419.9678YesYesYesYes80

Here, those paths that begin and end at given residue pair(s) or that pass through a residue are used to generate a novel metapath. Such a path filtering is particularly recommended if some information on allosteric residues is available. The selection syntax for a residue pair ("Pairs") is C:C:c534,A:A:?600 (the lower-case "c" stands for cytosine and "?" indicates any non standard amino acid or nucleotide residue). Selection of more than one apical residue pair has the following syntax: C:C:c534,A:A:?600,C:C:c534,A:A:E41. Only one residue can be selected as a tail ("Tail"). For midway residue(s), each residue must be separated by a comma as well e.g. A:A:?600,A:A:E41.

Midway



Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.


2D representation of the interactions of this orthosteric/allosteric ligand.


Node1Node2OwnerNet1LinkStrengthNet2LinkStrengthComm1Comm2Node1ShellNode2Shell
2x563x32Shared13.157.220831121
2x567x42Shared5.053.961671121
2x577x39Shared5.825.4850122
2x607x39Shared8.654.933051122
2x607x42Shared6.364.216671121
3x323x36Shared4.673.198331111
3x327x42Shared11.499.673061111
3x32LigShared11.7813.59311110
3x33LigShared4.7710.64940010
3x366x48Shared3.925.366941111
3x36LigShared5.39.077221110
3x374x53Shared6.44.726110012
3x375x4615ht1_off5.0300011
3x37LigShared4.923.245280010
3x405x475ht1_off3.7700112
3x405x50Shared5.083.342780112
3x406x44Shared11.34.534720112
3x40Lig5ht1_off4.7700110
E2x52LigShared3.987.983610010
5x445x48Shared6.243.817220112
5x44Lig5ht1_off3.9400110
5x475x48Shared11.355.070831122
5x476x52Shared33.2219.49721121
5x486x525ht1_off6.1901121
5x486x56Shared4.694.786391122
6x447x455ht1_off8.4600122
6x486x51Shared9.024.593061111
6x486x52Shared6.017.348611111
6x487x41Shared12.678.206111112
6x487x425ht1_off3.8601111
6x487x45Shared3.3910.42111112
6x48LigShared17.493.99751110
6x516x52Shared10.723.634171111
6x517x345ht1_off3.2201112
6x517x38Shared7.784.218331112
6x51LigShared15.4513.77831110
6x52LigShared13.838.968611110
6x547x34Shared5.023.10250122
7x387x425ht1_off6.2400021
7x397x42Shared6.758.949171121
7x42LigShared4.76.31751110
5x43LigShared3.015.050830010
6x556x565ht1_off300112
5x40Lig5ht1_off0.9800010
5x461Lig5ht1_on_gp03.082220010
2x577x425ht1_on_gp03.890830121
3x29E2x525ht1_on_gp03.16750021
3x334x575ht1_on_gp06.100280012
3x374x565ht1_on_gp05.953330012
3x406x485ht1_on_gp07.176950111
5x395x435ht1_on_gp06.1822201721
5x406x595ht1_on_gp04.825560012
5x446x565ht1_on_gp06.346670112
5x476x445ht1_on_gp07.651391122
5x476x485ht1_on_gp03.062781121
6x446x485ht1_on_gp05.542220121
6x516x555ht1_on_gp04.21251111
6x55Lig5ht1_on_gp07.340280110
6x516x545ht1_on_gp03.204171112

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Difference Members
Id Description
5ht1_on_gp 5ht1a_on_gp
5ht1d_on_gp
5ht1e_on_gp
5ht1f_on_gp
5ht1_off 5ht1b_off
Network Difference
Value 5ht1_on_gp 5ht1_off
Imin 2.92806 3.17
Number of Linked Nodes 906 241
Number of Specific Nodes 665 (73.40%) 0  (0.00%)
Number of Shared Nodes 241 (26.60%) 241  (100.00%)
Number of Links 1115 282
Number of Specific Links 955 (85.65%) 122  (43.26%)
Number of Shared Links 160 (14.35%) 160  (56.74%)
Number of Hubs 185 38
Number of Specific Hubs 162 (87.57%) 15  (39.47%)
Number of Shared Hubs 23 (12.43%) 23  (60.53%)
Average % Shared Neighbours (Jaccard) 11.03
Average % Shared Neighbours (Otsuka) 13.87
Average % Shared Neighbours (Overlap Coefficient) 16.67
Average % Shared Cliques (k3-6) 60.58
Graphlets Similarity 0.643023
Paths Difference
Value 5ht1_on_gp 5ht1_off
Number Of Nodes in MetaPath 88 69
Specific Nodes in MetaPath 80 (90.91%) 61  (88.41%)
Shared Nodes in MetaPath 241 (26.60%) 241  (26.60%)
Number Of Links MetaPath 87 70
Specific Links in MetaPath 87 (100.00%) 70  (100.00%)
Shared Links in MetaPath 160 (14.35%) 160  (14.35%)
Number of Shortest Paths 1592423 46833
Length Of Smallest Path 3 3
Average Path Length 28.4093 13.348
Length of Longest Path 64 37
Minimum Path Strength 0.286806 1.435
Average Path Strength 5.59979 6.43147
Maximum Path Strength 22.4211 23.525
Minimum Path Correlation 0.701944 0.7
Average Path Correlation 0.972738 0.927091
Maximum Path Correlation 1 0.99
Minimum % Of Corr. Nodes 1.85185 3.44828
Average % Of Corr. Nodes 37.129 50.1046
Maximum % Of Corr. Nodes 100 100
Minimum Path Hubs % 0 0
Average Path Hubs % 61.198 44.7762
Maximum Path Hubs % 100 100

Details about the values in these tables can be found in the corresponding documentation page .

You can download a compressed (zip) file with structure(s), 3D outputs (as PyMol and VMD scripts) and numerical data files (as csv and plain text files).

Download 5ht1_off_on_gp.zip<



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