Orange: nodes, hubs and links specific of 5ht2_on_gp network

Green: nodes, hubs and links shared by both networks

Purple: nodes, hubs and links specific of 5ht2_off network

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Owner: the name of the network the hub belong to or "Shared" if the corresponding hub is present in both networks.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub in the corresponding network.

Num Of Links: the number of links of the corresponding hub in the corresponding network.

ConSurf: this column reports the ConSurf conservation grades of each hub.


Index Hub Owner 5ht2_on_gp Avg Int. Strength 5ht2_off Avg Int. Strength 5ht2_on_gp Num Of Links 5ht2_off Num Of Links ConSurf
1G.HN.43 5ht2_on_gp2.8350409
2G.H1.01 5ht2_on_gp4.9760509
3G.S2.01 5ht2_on_gp3.730409
4G.S2.06 5ht2_on_gp5.4650609
5G.S2.08 5ht2_on_gp4.73250406
6G.S3.03 5ht2_on_gp6.170708
7G.S3.06 5ht2_on_gp8.8850407
8G.H2.06 5ht2_on_gp4.610609
9G.h2s4.01 5ht2_on_gp6.783330609
10G.S4.03 5ht2_on_gp3.1450407
11G.S4.04 5ht2_on_gp3.94750409
12G.S4.05 5ht2_on_gp5.220407
13G.S4.07 5ht2_on_gp6.82750408
14G.s4h3.02 5ht2_on_gp4.4950409
15G.s4h3.04 5ht2_on_gp7.73250408
16G.H3.08 5ht2_on_gp5.3540508
17G.H3.09 5ht2_on_gp4.2440509
18G.H3.12 5ht2_on_gp3.74250408
19G.H3.13 5ht2_on_gp7.438570706
20G.H3.17 5ht2_on_gp5.411670605
21G.S5.04 5ht2_on_gp4.3880509
22G.S5.05 5ht2_on_gp3.5850809
23G.HG.03 5ht2_on_gp5.9350406
24G.HG.15 5ht2_on_gp7.45250407
25G.hgh4.02 5ht2_on_gp2.8960508
26G.hgh4.05 5ht2_on_gp13.4450406
27G.hgh4.17 5ht2_on_gp8.5850404
28G.hgh4.20 5ht2_on_gp11.0940503
29G.H4.03 5ht2_on_gp5.9450404
30G.H4.04 5ht2_on_gp5.7350404
31G.H4.07 5ht2_on_gp6.450505
32G.H4.08 5ht2_on_gp5.5180503
33G.H4.10 5ht2_on_gp5.4340507
34G.H4.15 5ht2_on_gp4.8350608
35G.S6.02 5ht2_on_gp8.79750408
36G.S6.05 5ht2_on_gp8.970405
37G.s6h5.01 5ht2_on_gp4.1820509
38G.H5.03 5ht2_on_gp3.91750409
39G.H5.06 5ht2_on_gp90404
40G.H5.08 5ht2_on_gp6.080608
41G.H5.15 5ht2_on_gp3.57250408
42G.H5.16 5ht2_on_gp3.3940506
43G.H5.17 5ht2_on_gp3.260405
44G.H5.19 5ht2_on_gp4.5780508
45G.H5.22 5ht2_on_gp3.9850404
46G.H5.23 5ht2_on_gp5.2550404
47G.H5.25 5ht2_on_gp4.04750408
48b.1x11 5ht2_on_gp2.510408
49b.lhb1x6 5ht2_on_gp5.32250403
50b.l1x3 5ht2_on_gp8.3320509
51b.b2x3 5ht2_on_gp3.890406
52b.b2x5 5ht2_on_gp5.460607
53b.b3x2 5ht2_on_gp5.15750405
54b.l3x2 5ht2_on_gp70409
55b.b4x2 5ht2_on_gp6.0450408
56b.b4x5 5ht2_on_gp3.930407
57b.b4x6 5ht2_on_gp8.906670609
58b.l4x1 5ht2_on_gp3.420405
59b.b5x3 5ht2_on_gp5.335710709
60b.b5x7 5ht2_on_gp4.44250407
61b.l5x5 5ht2_on_gp7.062860709
62b.l6x5 5ht2_on_gp7.64250404
63b.b7x1 5ht2_on_gp6.890404
64b.l7x2 5ht2_on_gp4.080409
65b.b8x3 5ht2_on_gp3.20406
66b.b8x4 5ht2_on_gp6.0040506
67b.b9x4 5ht2_on_gp6.40409
68b.l9x3 5ht2_on_gp5.533330609
69b.l9x6 5ht2_on_gp3.5050608
70b.b10x5 5ht2_on_gp4.471430709
71b.l11x2 5ht2_on_gp6.870509
72b.b12x6 5ht2_on_gp8.626670608
73b.b13x7 5ht2_on_gp7.480507
74b.l13x3 5ht2_on_gp8.708330609
75b.b14x3 5ht2_on_gp4.46250405
76b.b15x1 5ht2_on_gp5.6560509
77b.b15x2 5ht2_on_gp3.5350406
78b.l15x1 5ht2_on_gp3.2420507
79b.l15x2 5ht2_on_gp7.040509
80b.b16x2 5ht2_on_gp4.1050405
81b.b16x4 5ht2_on_gp8.6940506
82b.b16x5 5ht2_on_gp4.1650405
83b.b16x6 5ht2_on_gp9.5340508
84b.l16x3 5ht2_on_gp8.90250403
85b.b17x5 5ht2_on_gp6.68750407
86b.b17x7 5ht2_on_gp6.73250408
87b.l17x3 5ht2_on_gp7.3160509
88b.l17x6 5ht2_on_gp6.6850409
89b.l17x7 5ht2_on_gp5.5450407
90b.b18x3 5ht2_on_gp4.7150408
91b.b18x5 5ht2_on_gp4.1720505
92b.l18x1 5ht2_on_gp6.7650606
93b.b19x2 5ht2_on_gp5.040606
94b.b19x4 5ht2_on_gp3.99250408
95b.l19x2 5ht2_on_gp3.89250409
96b.b20x3 5ht2_on_gp3.23250408
97b.b20x4 5ht2_on_gp9.8460508
98b.b20x6 5ht2_on_gp5.598330606
99b.b21x1 5ht2_on_gp8.360407
100b.b21x5 5ht2_on_gp5.2950404
101b.b21x7 5ht2_on_gp5.923330605
102b.l21x2 5ht2_on_gp4.3150404
103b.l21x7 5ht2_on_gp3.10750405
104b.b22x5 5ht2_on_gp5.5860507
105b.l22x5 5ht2_on_gp6.028570709
106b.b23x6 5ht2_on_gp5.542860707
107b.l23x1 5ht2_on_gp5.01750406
108b.b24x5 5ht2_on_gp3.4750405
109b.b24x7 5ht2_on_gp9.810409
110b.l25x3 5ht2_on_gp9.71250409
111b.l25x6 5ht2_on_gp8.5940508
112b.b26x3 5ht2_on_gp2.93750406
113b.b27x1 5ht2_on_gp3.410406
114b.l27x1 5ht2_on_gp11.02830609
115b.l27x2 5ht2_on_gp7.88250409
116b.b28x4 5ht2_on_gp5.04750406
117b.b28x6 5ht2_on_gp7.10409
118g.h1x11 5ht2_on_gp3.18250409
119g.ctx3 5ht2_on_gp5.7940509
120g.ctx4 5ht2_on_gp3.87250407
121g.ctx15 5ht2_on_gp5.99750409
122g.ctx16 5ht2_on_gp4.293330608
1232x40 5ht2_on_gp6.4228.10555539
124E1x52 5ht2_on_gp3.3846.08756536
1253x32 5ht2_on_gp8.9310.0638438
1263x37 5ht2_on_gp3.80753.63444437
1273x41 5ht2_on_gp5.898.07867426
128I2x51 5ht2_on_gp4.1522.83267517
1295x47 5ht2_on_gp6.9912.3376638
1305x48 5ht2_on_gp4.61255.20567426
1317x52 5ht2_on_gp2.60752.13633428
1327x54 5ht2_on_gp4.8454.00378437
1337x55 5ht2_on_gp2.64753.55567426
1348x58 5ht2_on_gp4.252.15867416
1351x50 Shared5.95.34667449
1362x42 Shared3.4344.17373558
1372x50 Shared6.1826.7565549
1382x57 Shared4.1284.67429578
139E1x50 Shared5.458336.77124677
1403x28 Shared5.1356.74017446
1413x35 Shared5.24256.33456
1423x42 Shared5.9556.6264658
1433x50 Shared6.1453.24293459
1444x50 Shared4.0825.1032559
145E2 Shared16.325510.735411134
1465x58 Shared7.46254.414449
1476x30 Shared5.0543.15267558
1486x44 Shared4.1166.9972559
1496x48 Shared5.4858.72693458
1506x51 Shared7.34757.08111467
1516x52 Shared7.61411.484557
1527x39 Shared4.5968.7404557
1537x42 Shared5.8186.09611568
1547x53 Shared5.1165.18267549
1558x50 Shared6.865.77308689
1568x54 Shared3.3025.7135547
157Lig Shared7.675567.790399120
1581x35 5ht2_off2.592.71617144
159I1x50 5ht2_off7.753337.45067348
1602x41 5ht2_off5.653334.77853355
1612x44 5ht2_off4.5054.015247
1623x24 5ht2_off3.562.9615345
1633x51 5ht2_off4.866.158348
1645x36 5ht2_off6.733336.42333345
1655x50 5ht2_off5.583335.628349
1666x41 5ht2_off4.4456.2536258
1677x37 5ht2_off4.9056.30483245
1687x56 5ht2_off15.732.73967147
1698x57 5ht2_off1.034.98347155
170NT 5ht2_off011.6183060
   
Orange: nodes, hubs and links specific of 5ht2_on_gp network

Green: nodes, hubs and links shared by both networks

Purple: nodes, hubs and links specific of 5ht2_off network

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Owner: the name of the network the link belong to or "Shared" if the corresponding link is present in both networks.

Recurrence: the relative Recurrence in the filtered pool of shortest paths.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.


Index Node1 Node2 Owner 5ht2_on_gp Recurrence 5ht2_off Recurrence 5ht2_on_gp Hub1? 5ht2_off Hub1? 5ht2_on_gp Hub2? 5ht2_off Hub2? ConSurf1 ConSurf2
1G.HN.47 b.b4x2 5ht2_on_gp17.46050NoNoYesNo58
2b.b4x2 b.b5x8 5ht2_on_gp18.50840YesNoNoNo85
3b.b5x7 b.b5x8 5ht2_on_gp18.5850YesNoNoNo75
4b.b5x7 b.b8x4 5ht2_on_gp19.0170YesNoYesNo76
5b.b8x4 b.l8x10 5ht2_on_gp20.09810YesNoNoNo64
6b.b9x3 b.l8x10 5ht2_on_gp20.17340NoNoNoNo64
7b.b9x3 b.l7x5 5ht2_on_gp20.3240NoNoNoNo66
8b.l7x3 b.l7x5 5ht2_on_gp20.54940NoNoNoNo96
9b.l5x3 b.l7x3 5ht2_on_gp20.62450NoNoNoNo89
10b.l5x3 b.l5x5 5ht2_on_gp20.69940NoNoYesNo89
11G.S3.06 b.l5x5 5ht2_on_gp50.80810YesNoYesNo79
12G.S3.04 G.S3.06 5ht2_on_gp99.9530NoNoYesNo77
13G.S2.03 G.S3.04 5ht2_on_gp99.96890NoNoNoNo97
14G.S2.02 G.S2.03 5ht2_on_gp99.97680NoNoNoNo59
15G.S2.02 G.S3.07 5ht2_on_gp99.99230NoNoNoNo59
16G.H1.01 G.S3.07 5ht2_on_gp1000YesNoNoNo99
17G.H1.01 G.S1.06 5ht2_on_gp94.77590YesNoNoNo98
18G.S1.06 G.S3.05 5ht2_on_gp47.44180NoNoNoNo88
19G.S2.06 G.S3.05 5ht2_on_gp47.41740YesNoNoNo98
20G.S2.06 G.S3.03 5ht2_on_gp47.32550YesNoYesNo98
21G.S1.06 G.S4.03 5ht2_on_gp47.34290NoNoYesNo87
22G.S1.04 G.S4.03 5ht2_on_gp48.88980NoNoYesNo77
23G.S1.04 G.S3.03 5ht2_on_gp48.85940NoNoYesNo78
24G.S1.02 G.S3.03 5ht2_on_gp92.45720NoNoYesNo68
25G.H5.15 G.S1.02 5ht2_on_gp92.32840YesNoNoNo86
26G.S1.05 G.h2s4.01 5ht2_on_gp10.37150NoNoYesNo99
27G.S1.05 G.S1.07 5ht2_on_gp10.20910NoNoNoNo98
28G.S1.07 G.S4.04 5ht2_on_gp10.47070NoNoYesNo89
29b.l5x5 b.l7x2 5ht2_on_gp44.57050YesNoYesNo99
30b.l13x6 b.l9x6 5ht2_on_gp17.2620NoNoYesNo98
31b.l7x2 b.l9x6 5ht2_on_gp80.30570YesNoYesNo98
32G.H2.06 b.l9x6 5ht2_on_gp57.54040YesNoYesNo98
33G.H2.06 b.l15x1 5ht2_on_gp16.87970YesNoYesNo97
34b.l13x6 b.l15x1 5ht2_on_gp16.90710NoNoYesNo97
35G.H2.06 b.l17x6 5ht2_on_gp40.18460YesNoYesNo99
36G.S4.04 G.S5.04 5ht2_on_gp10.41970YesNoYesNo99
37G.H5.15 G.H5.19 5ht2_on_gp47.13210YesNoYesNo88
38G.H5.15 I2x54 5ht2_on_gp46.30150YesNoNoNo86
39G.H5.19 G.H5.22 5ht2_on_gp46.24850YesNoYesNo84
40G.H5.22 I2x54 5ht2_on_gp46.21070YesNoNoNo46
412x37 2x40 5ht2_on_gp92.22051.4416NoNoYesNo79
422x37 G.H5.22 5ht2_on_gp92.31480NoNoYesNo74
432x40 8x50 5ht2_on_gp90.57992.54045YesNoYesYes99
442x50 7x49 5ht2_on_gp52.97680YesYesNoNo99
451x50 7x50 5ht2_on_gp85.08622.94874YesYesNoNo99
467x50 7x51 5ht2_on_gp85.28370NoNoNoNo96
477x51 7x55 5ht2_on_gp85.4811.49201NoNoYesNo66
487x54 7x55 5ht2_on_gp85.95510YesNoYesNo76
497x54 8x50 5ht2_on_gp88.00545.49927YesNoYesYes79
50b.l17x5 b.l17x6 5ht2_on_gp20.61290NoNoYesNo69
51b.l17x5 b.l19x2 5ht2_on_gp20.48250NoNoYesNo69
52b.b19x6 b.l19x2 5ht2_on_gp40.43460NoNoYesNo99
53b.b19x6 b.l17x3 5ht2_on_gp25.61130NoNoYesNo99
54b.b19x4 b.l17x3 5ht2_on_gp14.02210YesNoYesNo89
55b.b19x4 b.b20x6 5ht2_on_gp19.41650YesNoYesNo86
56b.b17x7 b.b20x6 5ht2_on_gp25.08580YesNoYesNo86
57b.b17x7 b.b21x1 5ht2_on_gp22.66890YesNoYesNo87
58b.1x19 b.b21x1 5ht2_on_gp18.63050NoNoYesNo67
59b.1x15 b.1x19 5ht2_on_gp15.39240NoNoNoNo76
60b.1x15 g.h1x15 5ht2_on_gp14.58280NoNoNoNo78
61b.1x11 g.h1x15 5ht2_on_gp13.77490YesNoNoNo88
62b.l17x6 b.l19x1 5ht2_on_gp20.61290YesNoNoNo99
63b.l19x1 b.l19x2 5ht2_on_gp20.48250NoNoYesNo99
64b.b19x6 b.l17x7 5ht2_on_gp14.5580NoNoYesNo97
65b.b19x4 b.l17x7 5ht2_on_gp14.02180YesNoYesNo87
66b.b20x4 b.l17x3 5ht2_on_gp11.05620YesNoYesNo89
67b.b4x6 b.b5x3 5ht2_on_gp16.01460YesNoYesNo99
68b.b3x2 b.b4x6 5ht2_on_gp15.67220YesNoYesNo59
69b.l26x5 g.ctx4 5ht2_on_gp12.97590NoNoYesNo57
70g.ctx3 g.ctx4 5ht2_on_gp12.65930YesNoYesNo97
71b.l13x5 b.l15x1 5ht2_on_gp34.62880NoNoYesNo57
72b.l13x5 b.l15x2 5ht2_on_gp34.09480NoNoYesNo59
73b.l13x3 b.l15x2 5ht2_on_gp25.71270YesNoYesNo99
74b.b11x5 b.l13x7 5ht2_on_gp11.91270NoNoNoNo69
75b.b11x5 b.b14x3 5ht2_on_gp10.83250NoNoYesNo65
76b.b15x1 b.b16x6 5ht2_on_gp12.46550YesNoYesNo98
77b.b16x4 b.l13x3 5ht2_on_gp10.02060YesNoYesNo69
78b.b11x1 b.l10x2 5ht2_on_gp11.38580NoNoNoNo55
793x28 E1x50 5ht2_on_gp15.79552.2985YesYesYesYes67
803x28 Lig 5ht2_on_gp17.89590YesYesYesYes60
813x36 Lig 5ht2_on_gp10.5311.46681NoNoYesYes70
823x36 6x48 5ht2_on_gp13.89780NoNoYesYes78
835x47 6x48 5ht2_on_gp14.31410YesNoYesYes88
845x47 6x44 5ht2_on_gp30.70260YesNoYesYes89
856x51 Lig 5ht2_on_gp21.06328.68995YesYesYesYes70
866x51 6x52 5ht2_on_gp29.05211.24502YesYesYesYes77
875x47 6x52 5ht2_on_gp14.94942.8076YesNoYesYes87
883x40 6x52 5ht2_on_gp14.94260NoNoYesYes87
895x461 Lig 5ht2_on_gp21.05220NoNoYesYes70
903x37 5x461 5ht2_on_gp21.46851.46681YesNoNoNo77
913x37 3x41 5ht2_on_gp11.35170YesNoYesNo76
923x41 4x49 5ht2_on_gp12.80580YesNoNoNo67
933x42 4x49 5ht2_on_gp13.01221.48697YesYesNoNo87
942x46 2x50 5ht2_on_gp27.43171.12909NoNoYesYes99
953x37 4x53 5ht2_on_gp11.38730YesNoNoNo78
963x38 4x53 5ht2_on_gp11.55571.59786NoNoNoNo88
973x38 3x42 5ht2_on_gp11.75180NoNoYesYes88
983x29 E2 5ht2_on_gp15.80050NoNoYesYes54
993x29 4x61 5ht2_on_gp18.95970NoNoNoNo56
1004x61 5x39 5ht2_on_gp23.17058.06996NoNoNoNo67
1015x39 Lig 5ht2_on_gp25.27550NoNoYesYes70
102G.HN.47 b.b5x3 5ht2_on_gp17.13350NoNoYesNo59
103G.S3.06 G.h2s4.01 5ht2_on_gp13.08270YesNoYesNo79
104G.S2.01 G.S3.06 5ht2_on_gp36.06670YesNoYesNo97
105G.S2.01 b.l7x2 5ht2_on_gp36.10540YesNoYesNo99
1063x43 7x49 Shared52.16569.2626NoNoNoNo99
1071x50 2x50 Shared82.872114.3606YesYesYesYes99
1083x43 6x44 Shared49.5398100NoNoYesYes99
1093x40 6x44 Shared15.573517.2942NoNoYesYes89
1102x46 3x42 Shared27.227123.5244NoNoYesYes98
1113x33 Lig 5ht2_off2.1075319.7742NoNoYesYes70
112E2x51 Lig 5ht2_off028.2524NoNoYesYes30
1136x48 Lig 5ht2_off071.8635YesYesYesYes80
1141x35 2x64 5ht2_off011.2657NoYesNoNo45
1152x64 7x39 5ht2_off0.63695122.7431NoNoYesYes57
1167x39 7x42 5ht2_off3.8199731.1709YesYesYesYes78
1172x57 7x42 5ht2_off3.8199713.2063YesYesYesYes88
1182x50 3x39 5ht2_off0.22063818.2519YesYesNoNo99
1193x39 6x44 5ht2_off042.9709NoNoYesYes99
1206x44 6x48 5ht2_off097.8779YesYesYesYes98
1211x52 8x54 5ht2_off2.5741122.1231NoNoYesYes77
1221x53 8x54 5ht2_off0.023963211.7244NoNoYesYes97
1231x53 7x53 5ht2_off012.672NoNoYesYes99
1247x49 7x53 5ht2_off060.7894NoNoYesYes99
1258x50 8x54 5ht2_off012.8383YesYesYesYes97
1267x53 8x50 5ht2_off046.5296YesYesYesYes99
1271x52 8x57 5ht2_off017.1329NoNoNoYes75
1281x57 8x50 5ht2_off0.88286615.7266NoNoYesYes89
1291x57 2x44 5ht2_off0.66222814.658NoNoNoYes87
1302x42 3x42 5ht2_off1.2975514.0481YesYesYesYes88
1312x46 3x39 5ht2_off023.6302NoNoNoNo99
1323x33 4x57 5ht2_off1.0537810.4945NoNoNoNo78
1332x64 E1 5ht2_off012.1175NoNoNoNo54
134E2 E2x51 5ht2_off1.0537827.4207YesYesNoNo43
1353x33 4x61 5ht2_off011.0792NoNoNoNo76
1363x40 5x50 5ht2_off0.45141615.9081NoNoNoYes89
1373x43 6x41 5ht2_off058.2489NoNoNoYes98
1383x47 6x41 5ht2_off015.8425NoNoNoYes98
1393x47 5x57 5ht2_off0.2180114.5118NoNoNoNo96
1406x37 6x41 5ht2_off028.9581NoNoNoYes88
1413x50 6x37 5ht2_off0.21772527.6274YesYesNoNo98
1423x50 6x30 5ht2_off023.3278YesYesYesYes98
1433x51 5x57 5ht2_off013.1055NoYesNoNo86
1445x44 6x52 5ht2_off0.43433614.1691NoNoYesYes77
1455x58 6x41 5ht2_off1.3073511.1145YesYesNoYes98
1466x40 7x49 5ht2_off011.6891NoNoNoNo89
1476x51 7x34 5ht2_off1.6992720.8629YesYesNoNo75
1486x54 7x34 5ht2_off1.2745319.8347NoNoNoNo55
1496x54 7x37 5ht2_off0.84973515.0108NoNoNoYes55
1505x44 6x56 5ht2_off0.0034845112.7678NoNoNoNo76
1516x40 7x52 5ht2_off5.71231e-0510.2525NoNoYesNo88
1527x42 Lig 5ht2_off044.1857YesYesYesYes80
153E1x50 E2 5ht2_off015.8173YesYesYesYes74
1546x48 6x52 5ht2_off0.0015994511.2657YesYesYesYes87
1556x48 6x51 5ht2_off014.4463YesYesYesYes87

Here, those paths that begin and end at given residue pair(s) or that pass through a residue are used to generate a novel metapath. Such a path filtering is particularly recommended if some information on allosteric residues is available. The selection syntax for a residue pair ("Pairs") is C:C:c534,A:A:?600 (the lower-case "c" stands for cytosine and "?" indicates any non standard amino acid or nucleotide residue). Selection of more than one apical residue pair has the following syntax: C:C:c534,A:A:?600,C:C:c534,A:A:E41. Only one residue can be selected as a tail ("Tail"). For midway residue(s), each residue must be separated by a comma as well e.g. A:A:?600,A:A:E41.

Midway



Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.


2D representation of the interactions of this orthosteric/allosteric ligand.


Node1Node2OwnerNet1LinkStrengthNet2LinkStrengthComm1Comm2Node1ShellNode2Shell
3x32LigShared15.767318.041510
3x33LigShared7.6446715.140010
3x36LigShared10.8425.870510
3x37Lig5ht2_off3.83800010
E2x51Lig5ht2_off5.00601010
5x47Lig5ht2_off3.5753301510
6x48Lig5ht2_off10.18601510
6x51LigShared12.144715.231510
6x52Lig5ht2_off11.902701510
7x38LigShared7.1944.661510
7x42Lig5ht2_off4.13601510
2x563x28Shared4.1686.131521
2x563x32Shared6.911332.921521
2x567x42Shared4.040673.791521
2x577x39Shared6.202673.491522
2x577x42Shared6.144674.791521
2x593x28Shared12.34737.050021
3x28E1x50Shared7.060674.690012
E1x50E25ht2_off3.874011422
3x327x42Shared7.5126710.341511
3x334x57Shared3.715333.390012
3x334x615ht2_off3.6066700012
3x375x461Shared4.734673.360011
3x406x44Shared5.363.770022
4x605x395ht2_off4.3326700021
4x615x39Shared4.342673.930021
E2E2Shared30.353368.131822
5x36E2Shared12.5845.541822
E2E2x51Shared6.095331.591821
5x365x395ht2_off6.7646701821
5x406x55Shared4.8727.010021
5x446x52Shared4.843.960521
5x476x52Shared27.14818.221511
6x446x485ht2_off8.7533300521
6x486x515ht2_off6.6826701511
6x486x52Shared5.812678.021511
6x487x41Shared12.28.441512
6x516x52Shared7.716675.361511
6x516x555ht2_off6.52401511
6x517x34Shared4.794.871512
6x517x38Shared4.628673.931511
6x557x345ht2_off4.9433301012
7x387x42Shared4.710676.311511
7x397x42Shared10.0323.861521
5x475x48Shared6.289339.651512
3x283x295ht2_off3.3846700012
3x374x56Shared2.330673.040012
5x43Lig5ht2_off1.24800010
3x28Lig5ht2_on_gp02.670010
3x294x615ht2_on_gp04.470822
3x29E25ht2_on_gp02.850822
3x323x365ht2_on_gp04.421511
3x366x485ht2_on_gp02.470511
3x373x415ht2_on_gp02.430012
3x374x535ht2_on_gp06.40012
3x406x525ht2_on_gp02.510021
5x395x435ht2_on_gp03.010011
5x39Lig5ht2_on_gp02.860010
5x445x485ht2_on_gp02.640522
5x461Lig5ht2_on_gp02.460010
5x475x515ht2_on_gp03.651512
5x476x445ht2_on_gp03.221512
5x476x485ht2_on_gp03.011511
5x476x495ht2_on_gp04.191512
5x516x445ht2_on_gp02.440522
6x55Lig5ht2_on_gp02.151010

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Difference Members
Id Description
5ht2_on_gp 5ht2b_on_gp
5ht2_off 5ht2a_off
5ht2b_off
5ht2c_off
Network Difference
Value 5ht2_on_gp 5ht2_off
Imin 2.39 3.44133
Number of Linked Nodes 827 274
Number of Specific Nodes 589 (71.22%) 36  (13.14%)
Number of Shared Nodes 238 (28.78%) 238  (86.86%)
Number of Links 1014 302
Number of Specific Links 857 (84.52%) 145  (48.01%)
Number of Shared Links 157 (15.48%) 157  (51.99%)
Number of Hubs 157 36
Number of Specific Hubs 134 (85.35%) 13  (36.11%)
Number of Shared Hubs 23 (14.65%) 23  (63.89%)
Average % Shared Neighbours (Jaccard) 12.45
Average % Shared Neighbours (Otsuka) 15.23
Average % Shared Neighbours (Overlap Coefficient) 17.89
Average % Shared Cliques (k3-6) 51.50
Graphlets Similarity 0.674233
Paths Difference
Value 5ht2_on_gp 5ht2_off
Number Of Nodes in MetaPath 105 50
Specific Nodes in MetaPath 89 (84.76%) 34  (68.00%)
Shared Nodes in MetaPath 238 (28.78%) 238  (28.78%)
Number Of Links MetaPath 110 50
Specific Links in MetaPath 105 (95.45%) 45  (90.00%)
Shared Links in MetaPath 157 (15.48%) 157  (15.48%)
Number of Shortest Paths 4197410 41686
Length Of Smallest Path 3 3
Average Path Length 40.5807 10.8116
Length of Longest Path 72 22
Minimum Path Strength 1.3 0.613
Average Path Strength 5.78907 5.67348
Maximum Path Strength 21.76 17.4323
Minimum Path Correlation 0.7 0.702667
Average Path Correlation 0.990315 0.915171
Maximum Path Correlation 1 0.988667
Minimum % Of Corr. Nodes 2.17391 5.88235
Average % Of Corr. Nodes 27.3724 51.5714
Maximum % Of Corr. Nodes 100 100
Minimum Path Hubs % 0 0
Average Path Hubs % 53.9009 44.9206
Maximum Path Hubs % 100 100

Details about the values in these tables can be found in the corresponding documentation page .

You can download a compressed (zip) file with structure(s), 3D outputs (as PyMol and VMD scripts) and numerical data files (as csv and plain text files).

Download 5ht2_off_on_gp.zip<



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