Orange: nodes, hubs and links specific of 5ht_on_gp network

Green: nodes, hubs and links shared by both networks

Purple: nodes, hubs and links specific of 5ht_off network

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Owner: the name of the network the hub belong to or "Shared" if the corresponding hub is present in both networks.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub in the corresponding network.

Num Of Links: the number of links of the corresponding hub in the corresponding network.

ConSurf: this column reports the ConSurf conservation grades of each hub.


Index Hub Owner 5ht_on_gp Avg Int. Strength 5ht_off Avg Int. Strength 5ht_on_gp Num Of Links 5ht_off Num Of Links ConSurf
1G.HN.32 5ht_on_gp00405
2G.H1.01 5ht_on_gp56.01850409
3G.S2.06 5ht_on_gp16.66670403
4G.S2.08 5ht_on_gp63.88890403
5G.S3.03 5ht_on_gp79.16670604
6G.S3.04 5ht_on_gp50.92590407
7G.S3.06 5ht_on_gp91.66670507
8G.H2.06 5ht_on_gp99.5370708
9G.H2.07 5ht_on_gp58.33330409
10G.h2s4.01 5ht_on_gp74.5370507
11G.S4.04 5ht_on_gp65.27780507
12G.s4h3.04 5ht_on_gp60.18520608
13G.s4h3.15 5ht_on_gp00406
14G.H3.01 5ht_on_gp00709
15G.H3.09 5ht_on_gp99.07410609
16G.H3.13 5ht_on_gp500508
17G.H3.17 5ht_on_gp88.88890704
18G.H3.18 5ht_on_gp40.27780405
19G.S5.05 5ht_on_gp81.94440709
20G.S5.07 5ht_on_gp00508
21G.s5hg.01 5ht_on_gp8.333330409
22G.HG.01 5ht_on_gp250409
23G.HG.03 5ht_on_gp00409
24G.HG.07 5ht_on_gp16.66670405
25G.hgh4.01 5ht_on_gp44.44440503
26G.hgh4.02 5ht_on_gp65.27780506
27G.hgh4.05 5ht_on_gp93.51850506
28G.H4.03 5ht_on_gp16.66670405
29G.H4.10 5ht_on_gp72.22220603
30G.H4.12 5ht_on_gp00407
31G.H4.15 5ht_on_gp75.4630405
32G.H4.16 5ht_on_gp00408
33G.h4s6.02 5ht_on_gp5.555560404
34G.h4s6.12 5ht_on_gp00407
35G.S6.02 5ht_on_gp94.44440605
36G.S6.05 5ht_on_gp41.66670409
37G.H5.02 5ht_on_gp00409
38G.H5.08 5ht_on_gp98.61110508
39G.H5.13 5ht_on_gp00406
40G.H5.17 5ht_on_gp40.27780406
41G.H5.20 5ht_on_gp16.66670408
42G.H5.26 5ht_on_gp5.092590407
43b.1x7 5ht_on_gp00408
44b.lhb1x6 5ht_on_gp16.66670403
45b.l1x3 5ht_on_gp1000609
46b.b2x1 5ht_on_gp60.18520508
47b.b2x5 5ht_on_gp1000607
48b.b3x3 5ht_on_gp18.51850408
49b.l3x2 5ht_on_gp61.11110509
50b.b4x6 5ht_on_gp1000609
51b.l4x2 5ht_on_gp44.44440404
52b.b5x2 5ht_on_gp00407
53b.b5x3 5ht_on_gp91.66670609
54b.b5x5 5ht_on_gp41.66670405
55b.b5x7 5ht_on_gp36.11110407
56b.l5x1 5ht_on_gp55.09260508
57b.l5x5 5ht_on_gp1000609
58b.b6x5 5ht_on_gp59.72220506
59b.l6x5 5ht_on_gp50.4630404
60b.b7x1 5ht_on_gp57.40740404
61b.l7x4 5ht_on_gp4.166670409
62b.l7x5 5ht_on_gp00406
63b.b8x4 5ht_on_gp83.33330506
64b.b9x3 5ht_on_gp8.333330406
65b.l9x3 5ht_on_gp95.83330509
66b.l9x6 5ht_on_gp1000708
67b.b10x5 5ht_on_gp52.31480509
68b.l10x1 5ht_on_gp40.27780403
69b.b11x5 5ht_on_gp00406
70b.l11x2 5ht_on_gp57.87040409
71b.b12x6 5ht_on_gp1000608
72b.l12x1 5ht_on_gp00406
73b.b13x7 5ht_on_gp1000507
74b.l13x3 5ht_on_gp1000609
75b.l13x6 5ht_on_gp81.94440509
76b.l13x7 5ht_on_gp61.57410409
77b.b14x3 5ht_on_gp24.07410405
78b.b15x1 5ht_on_gp66.20370509
79b.l15x1 5ht_on_gp63.88890407
80b.l15x2 5ht_on_gp69.44440509
81b.b16x4 5ht_on_gp99.07410406
82b.b16x6 5ht_on_gp1000608
83b.l16x3 5ht_on_gp16.66670403
84b.b17x5 5ht_on_gp500407
85b.b17x7 5ht_on_gp1000408
86b.l17x3 5ht_on_gp1000509
87b.l17x6 5ht_on_gp80.55550509
88b.b18x3 5ht_on_gp99.07410408
89b.l18x1 5ht_on_gp1000706
90b.l18x3 5ht_on_gp41.66670405
91b.b19x2 5ht_on_gp99.5370506
92b.b19x4 5ht_on_gp71.29630408
93b.l19x1 5ht_on_gp19.44440409
94b.l19x2 5ht_on_gp75.4630409
95b.b20x4 5ht_on_gp1000608
96b.b20x6 5ht_on_gp99.5370506
97b.b20x7 5ht_on_gp23.61110409
98b.l20x2 5ht_on_gp27.77780409
99b.b21x1 5ht_on_gp94.44440407
100b.b21x5 5ht_on_gp38.88890404
101b.b21x7 5ht_on_gp91.20370705
102b.l21x2 5ht_on_gp00404
103b.l21x7 5ht_on_gp00505
104b.b22x5 5ht_on_gp55.09260507
105b.l22x5 5ht_on_gp73.14810609
106b.b23x1 5ht_on_gp22.22220405
107b.b23x6 5ht_on_gp1000707
108b.l23x1 5ht_on_gp500406
109b.b24x4 5ht_on_gp51.85190406
110b.b24x6 5ht_on_gp31.94440408
111b.l24x3 5ht_on_gp250405
112b.b25x3 5ht_on_gp24.07410405
113b.l25x3 5ht_on_gp99.07410509
114b.l25x6 5ht_on_gp73.61110408
115b.l26x1 5ht_on_gp8.333330407
116b.l27x1 5ht_on_gp1000609
117b.l27x2 5ht_on_gp65.27780409
118b.b28x3 5ht_on_gp00407
119b.b28x4 5ht_on_gp99.07410406
120b.b28x6 5ht_on_gp1000609
121g.h1x11 5ht_on_gp00509
122g.l1x4 5ht_on_gp11.11110408
123g.h2x9 5ht_on_gp00404
124g.h2x11 5ht_on_gp43.05560406
125g.ctx3 5ht_on_gp85.64820609
126g.ctx5 5ht_on_gp22.22220409
127g.ctx6 5ht_on_gp250606
128g.ctx14 5ht_on_gp47.22220509
129g.ctx15 5ht_on_gp47.22220409
130g.ctx16 5ht_on_gp1000808
1311x50 5ht_on_gp41.66670439
1321x60 5ht_on_gp250537
1332x46 5ht_on_gp58.79630529
1342x65 5ht_on_gp00426
1353x24 5ht_on_gp16.66670526
1363x46 5ht_on_gp16.66670419
1373x52 5ht_on_gp33.333350425
1384x50 5ht_on_gp33.333383.3333439
1395x47 5ht_on_gp10050638
1405x50 5ht_on_gp27.77780439
1415x54 5ht_on_gp16.66670429
142E3 5ht_on_gp32.40740514
1437x49 5ht_on_gp54.16670539
1447x53 5ht_on_gp98.14820629
145I3 5ht_on_gp4.166670400
146G.hgh4.20 5ht_on_gp250400
147Lig Shared10010010130
148I1x50 Shared44.444433.3333548
1492x42 Shared58.333316.6667548
1502x50 Shared81.481583.3333559
1512x56 Shared5050448
1522x57 Shared44.4444100458
153E1x50 Shared91.6667100669
1543x32 Shared65.277850448
1553x42 Shared55.555683.3333458
1563x49 Shared8.3333350449
157I2x53 Shared52.777850448
158E2 Shared99.074110013114
1595x48 Shared31.944450457
1605x58 Shared86.11110749
1616x44 Shared72.2222100549
1626x48 Shared100100758
1636x51 Shared40.2778100468
1646x52 Shared69.444496.6667567
1657x39 Shared56.9444100568
1667x42 Shared100100578
1678x50 Shared10050748
168E1x52 5ht_off16.66670347
1693x28 5ht_off41.666750356
1703x50 5ht_off48.14810349
1713x51 5ht_off45.370450349
1723x56 5ht_off00247
1735x36 5ht_off00246
1745x64 5ht_off050146
1756x31 5ht_off00146
1766x41 5ht_off033.3333268
1777x37 5ht_off050356
1788x57 5ht_off033.3333247
179CT 5ht_off00150
180NT 5ht_off083.3333170
   
Orange: nodes, hubs and links specific of 5ht_on_gp network

Green: nodes, hubs and links shared by both networks

Purple: nodes, hubs and links specific of 5ht_off network

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Owner: the name of the network the link belong to or "Shared" if the corresponding link is present in both networks.

Recurrence: the relative Recurrence in the filtered pool of shortest paths.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.


Index Node1 Node2 Owner 5ht_on_gp Recurrence 5ht_off Recurrence 5ht_on_gp Hub1? 5ht_off Hub1? 5ht_on_gp Hub2? 5ht_off Hub2? ConSurf1 ConSurf2
1b.l26x5 g.ctx15 5ht_on_gp10.92880NoNoYesNo59
2b.l26x5 g.ctx4 5ht_on_gp19.20040NoNoNoNo57
3g.ctx3 g.ctx4 5ht_on_gp19.3830YesNoNoNo97
4g.ctx3 g.ctx6 5ht_on_gp27.15780YesNoYesNo96
5b.l22x5 g.ctx6 5ht_on_gp29.12270YesNoYesNo96
6b.l22x5 b.l24x2 5ht_on_gp30.8850YesNoNoNo96
7b.h2x5 b.l24x2 5ht_on_gp31.24750NoNoNoNo56
8b.h2x1 b.h2x5 5ht_on_gp33.43860NoNoNoNo55
9b.b21x5 b.h2x1 5ht_on_gp33.54080YesNoNoNo45
10b.b21x5 b.b21x7 5ht_on_gp34.250YesNoYesNo45
11b.b21x7 b.b24x6 5ht_on_gp41.05590YesNoYesNo58
12b.b23x6 b.b24x6 5ht_on_gp41.36120YesNoYesNo78
13b.b23x6 b.l21x7 5ht_on_gp44.04880YesNoYesNo75
14b.l21x7 b.l23x1 5ht_on_gp45.30290YesNoYesNo56
15G.H3.17 b.l23x1 5ht_on_gp43.56270YesNoYesNo46
16G.H3.15 G.H3.17 5ht_on_gp41.12030NoNoYesNo84
17G.H3.15 G.H3.18 5ht_on_gp41.27170NoNoYesNo85
18G.H3.18 G.S4.02 5ht_on_gp41.56880YesNoNoNo58
19G.S1.05 G.S4.02 5ht_on_gp41.87740NoNoNoNo98
20G.S1.05 G.S1.07 5ht_on_gp44.05590NoNoNoNo99
21G.S1.07 G.S4.04 5ht_on_gp44.32840NoNoYesNo97
22G.S4.04 G.S4.06 5ht_on_gp32.47430YesNoNoNo77
23G.H4.15 G.S4.06 5ht_on_gp32.54510YesNoNoNo57
24G.H3.06 G.H4.15 5ht_on_gp99.78060NoNoYesNo95
25G.H3.06 G.hgh4.02 5ht_on_gp99.7870NoNoYesNo96
26G.hgh4.01 G.hgh4.02 5ht_on_gp98.89330YesNoYesNo36
27G.hgh4.01 G.s4h3.04 5ht_on_gp98.9520YesNoYesNo38
28G.HG.07 G.s4h3.04 5ht_on_gp99.85980YesNoYesNo58
29G.HG.07 G.s4h3.02 5ht_on_gp99.91950YesNoNoNo57
30G.s4h3.02 G.s5hg.01 5ht_on_gp99.79240NoNoYesNo79
31G.S5.07 G.s5hg.01 5ht_on_gp1000YesNoYesNo89
32G.H1.04 G.S5.07 5ht_on_gp49.94180NoNoYesNo98
33G.H1.04 G.S5.05 5ht_on_gp49.92130NoNoYesNo99
34G.H3.09 G.S4.04 5ht_on_gp32.69220YesNoYesNo97
35G.H3.09 G.H4.15 5ht_on_gp33.28980YesNoYesNo95
36G.S4.04 G.S5.04 5ht_on_gp32.88960YesNoNoNo78
37G.H4.15 G.S5.04 5ht_on_gp33.96570YesNoNoNo58
38G.S5.07 G.s6h5.01 5ht_on_gp50.07510YesNoNoNo84
39G.S5.05 G.s6h5.01 5ht_on_gp49.92120YesNoNoNo94
40G.H2.07 b.l9x6 5ht_on_gp60.59150YesNoYesNo98
41G.H2.06 b.l9x6 5ht_on_gp33.41630YesNoYesNo88
42G.H2.04 G.H2.07 5ht_on_gp53.06440NoNoYesNo99
43G.H3.08 G.S4.04 5ht_on_gp53.57750NoNoYesNo57
44G.H2.06 b.l17x6 5ht_on_gp16.29260YesNoYesNo89
45G.H2.06 b.l19x1 5ht_on_gp16.29280YesNoYesNo89
46G.S5.03 G.S5.05 5ht_on_gp47.97790NoNoYesNo69
47G.H5.10 G.S5.03 5ht_on_gp47.82010NoNoNoNo46
48G.H5.10 G.S6.02 5ht_on_gp95.51550NoNoYesNo45
49G.S5.05 G.S6.04 5ht_on_gp48.33310YesNoNoNo95
50G.H5.10 G.S6.04 5ht_on_gp47.85970NoNoNoNo45
51G.H5.13 G.S6.02 5ht_on_gp93.32360YesNoYesNo65
525x68 G.H5.13 5ht_on_gp92.90390NoNoYesNo76
535x68 G.H5.16 5ht_on_gp92.25240NoNoNoNo77
54G.H5.16 I2x50 5ht_on_gp92.08220NoNoNoNo78
553x53 G.H5.19 5ht_on_gp91.24420NoNoNoNo84
56G.H5.15 G.H5.19 5ht_on_gp91.74170NoNoNoNo74
57G.H5.15 I2x50 5ht_on_gp91.91190NoNoNoNo78
583x54 G.H5.20 5ht_on_gp12.63210NoNoYesNo98
593x54 G.H5.23 5ht_on_gp13.00790NoNoNoNo94
603x50 G.H5.23 5ht_on_gp13.38360NoYesNoNo94
613x46 3x50 5ht_on_gp13.15170YesNoNoYes99
622x42 3x46 5ht_on_gp84.97841.94423YesYesYesNo89
632x42 3x49 5ht_on_gp89.21010YesYesYesYes89
643x49 I2x53 5ht_on_gp89.5319.8286YesYesYesYes98
653x53 I2x53 5ht_on_gp91.07370NoNoYesYes88
66b.l17x5 b.l17x6 5ht_on_gp16.43570NoNoYesNo69
67b.l17x5 b.l19x2 5ht_on_gp32.2220NoNoYesNo69
68b.b20x2 b.l19x2 5ht_on_gp26.2280NoNoYesNo69
69b.b20x2 b.b20x4 5ht_on_gp25.52590NoNoYesNo68
70b.b20x4 b.b20x6 5ht_on_gp24.12270YesNoYesNo86
71b.b17x7 b.b20x6 5ht_on_gp20.60380YesNoYesNo86
72b.b17x7 b.b21x1 5ht_on_gp16.37670YesNoYesNo87
73b.1x19 b.b21x1 5ht_on_gp14.97840NoNoYesNo67
74b.1x15 b.1x19 5ht_on_gp13.56660NoNoNoNo76
75b.1x15 g.h1x11 5ht_on_gp12.50740NoNoYesNo79
76b.l17x5 b.l19x1 5ht_on_gp16.13720NoNoYesNo69
77b.l11x1 b.l9x6 5ht_on_gp25.89230NoNoYesNo98
78b.b11x6 b.l11x1 5ht_on_gp26.02840NoNoNoNo99
79b.b11x6 b.l9x3 5ht_on_gp24.96490NoNoYesNo99
80b.b11x4 b.l9x3 5ht_on_gp18.40540NoNoYesNo99
81b.b10x3 b.b11x4 5ht_on_gp18.30550NoNoNoNo89
82b.b10x3 b.b6x2 5ht_on_gp18.1290NoNoNoNo88
83b.b10x2 b.b6x2 5ht_on_gp17.95240NoNoNoNo68
84b.b10x2 b.b10x4 5ht_on_gp10.30790NoNoNoNo66
852x46 3x46 5ht_on_gp40.25090YesNoYesNo99
863x36 6x48 5ht_on_gp19.77230NoNoYesYes78
876x48 7x45 5ht_on_gp49.92830YesYesNoNo89
882x46 7x49 5ht_on_gp25.35510YesNoYesNo99
897x49 7x53 5ht_on_gp25.73970YesNoYesNo99
903x46 7x53 5ht_on_gp31.66280YesNoYesNo99
913x36 Lig 5ht_on_gp18.95961.38143NoNoYesYes70
926x48 6x52 5ht_on_gp23.71752.81914YesYesYesYes87
935x43 Lig 5ht_on_gp23.3752.13865NoNoYesYes80
945x39 E2 5ht_on_gp18.96150NoNoYesYes84
955x39 5x43 5ht_on_gp22.63950NoNoNoNo88
96G.H2.04 G.H3.08 5ht_on_gp53.2890NoNoNoNo95
972x53 7x46 Shared10.106136.8943NoNoNoNo89
982x50 7x46 Shared10.290436.2394YesYesNoNo99
992x46 2x50 Shared13.097157.1348YesNoYesYes99
1007x45 7x49 Shared50.65142.4047NoNoYesNo99
1016x52 Lig Shared19.033314.9092YesYesYesYes70
1021x46 2x57 5ht_off021.6372NoNoYesYes88
1031x46 2x54 5ht_off012.1207NoNoNoNo88
1047x39 7x42 5ht_off4.6897441.3405YesYesYesYes88
1052x56 7x42 5ht_off5.6528152.4226YesYesYesYes88
1062x53 2x56 5ht_off9.0087238.3116NoNoYesYes88
1071x50 2x50 5ht_off2.6745514.2799YesNoYesYes99
1082x46 3x42 5ht_off1.514156.1422YesNoYesYes98
1093x42 4x46 5ht_off094.6431YesYesNoNo88
1102x42 4x46 5ht_off2.3724593.5943YesYesNoNo88
1112x42 3x45 5ht_off0.3834589.3988YesYesNoNo88
1123x45 4x45 5ht_off0.19173687.9253NoNoNoNo86
1133x49 4x45 5ht_off082.1642YesYesNoNo96
1143x49 3x50 5ht_off059.4014YesYesNoYes99
1152x39 3x50 5ht_off054.7915NoNoNoYes89
1162x37 2x39 5ht_off053.2003NoNoNoNo88
1172x37 2x40 5ht_off0.19051551.5477NoNoNoNo89
1182x40 I1x50 5ht_off0.00052628444.835NoNoYesYes98
1198x50 I1x50 5ht_off2.2365235.0115YesYesYesYes88
1201x56 8x50 5ht_off028.2988NoNoYesYes88
1211x52 1x56 5ht_off024.6815NoNoNoNo88
1227x42 Lig 5ht_off0100YesYesYesYes80
1233x37 Lig 5ht_off051.6654NoNoYesYes80
1243x37 4x53 5ht_off0.73690348.923NoNoNoNo88
1253x38 4x53 5ht_off047.782NoNoNoNo88
1263x38 4x50 5ht_off0.18994646.7281NoNoYesNo89
1273x42 4x50 5ht_off0.024861645.2341YesYesYesNo89
1281x52 8x57 5ht_off019.4935NoNoNoYes87
1293x49 I2x57 5ht_off0.02090416.5874YesYesNoNo98
1302x38 I2x57 5ht_off0.19173615.3287NoNoNoNo78
1312x38 4x39 5ht_off013.4971NoNoNoNo75
1322x50 7x49 5ht_off0.17718939.2172YesYesYesNo99
1336x48 Lig 5ht_off028.2169YesYesYesYes80
1346x44 6x48 5ht_off1.1945235.2571YesYesYesYes98
1356x44 7x45 5ht_off045.7611YesYesNoNo99
1363x40 Lig 5ht_off066.6871NoNoYesYes80
1373x40 6x44 5ht_off0.003115638.6339NoNoYesYes89
1383x33 Lig 5ht_off5.1560924.2415NoNoYesYes80
1393x33 4x57 5ht_off4.419622.2103NoNoNoNo88
1403x34 4x57 5ht_off1.4735916.4288NoNoNoNo68
1412x60 3x28 5ht_off036.9557NoNoNoYes76
1423x28 E1x50 5ht_off1.8877493.7375NoYesYesYes69
143E1x50 E1x52 5ht_off0.37768221.1768YesYesNoYes97
1443x25 E1x50 5ht_off0.18895757.6516NoNoYesYes99
1453x24 E1x52 5ht_off0.00018946210.6319YesNoNoYes67
1463x25 E2 5ht_off054.3106NoNoYesYes94
1473x40 5x50 5ht_off0.040881752.484NoNoYesNo89
1483x41 5x50 5ht_off0.75624948.9946NoNoYesNo79
1493x41 3x44 5ht_off037.2474NoNoNoNo77
1503x43 6x44 5ht_off062.1489NoNoYesYes89
1513x44 5x53 5ht_off0.19440943.4433NoNoNoNo77
1523x43 6x41 5ht_off059.9335NoNoNoYes88
1535x54 6x41 5ht_off013.9524YesNoNoYes98
1543x44 5x54 5ht_off0.38753412.4533NoNoYesNo79
1555x53 5x57 5ht_off041.0386NoNoNoNo77
1563x51 5x57 5ht_off1.1405436.1934NoYesNoNo97
1573x51 3x55 5ht_off0.38033524.7787NoYesNoNo98
1583x55 5x64 5ht_off0.19017812.2333NoNoNoYes86
1593x55 3x56 5ht_off010.2481NoNoNoYes87
1603x41 4x52 5ht_off1.1115512.6733NoNoNoNo75
1615x36 E2 5ht_off1.4734927.0606NoYesYesYes64
1625x36 5x39 5ht_off020.1484NoYesNoNo68
1635x58 6x41 5ht_off0.56988137.1348YesYesNoYes98
1645x58 5x62 5ht_off027.5774YesYesNoNo96
1655x62 6x31 5ht_off024.9885NoNoNoYes66
1666x31 6x32 5ht_off012.6222NoYesNoNo68
1676x40 7x49 5ht_off012.704NoNoYesNo89
1686x40 7x52 5ht_off0.003852410.6114NoNoNoNo88
1697x38 7x42 5ht_off0.23939613.6812NoNoYesYes78
1706x51 7x38 5ht_off0.38138713.3947YesYesNoNo87
1716x51 Lig 5ht_off0.0014946530.33YesYesYesYes80
1726x51 7x34 5ht_off044.3796YesYesNoNo84
1736x54 7x34 5ht_off3.6834427.782NoNoNoNo64
1746x54 7x37 5ht_off2.9468316.7869NoNoNoYes66
1756x58 7x34 5ht_off0.00010525715.0166NoNoNoNo44
1766x61 7x30 5ht_off013.758NoNoNoNo57
1778x57 CT 5ht_off014.2287NoYesNoYes70
1781x42 2x57 5ht_off016.3776NoNoYesYes78
1791x42 7x43 5ht_off012.1207NoNoNoNo75
1802x64 7x39 5ht_off0.57777538.7363NoNoYesYes78
1812x64 E1 5ht_off037.0888NoNoNoNo70
1827x35 E1 5ht_off035.4925NoNoNoNo60
1837x35 NT 5ht_off031.9007NoNoNoYes60
1841x32 NT 5ht_off016.2139NoNoNoYes40
1851x32 1x35 5ht_off0.72225110.0588NoNoNoNo45
1862x57 7x42 5ht_off0.76818538.5674YesYesYesYes88
1872x60 7x42 5ht_off031.3993NoNoYesYes78
1882x56 3x28 5ht_off3.0199266.8662YesYesNoYes86
1892x56 3x32 5ht_off0.25562726.5797YesYesYesYes88
1903x32 Lig 5ht_off0.094583726.8969YesYesYesYes80

Here, those paths that begin and end at given residue pair(s) or that pass through a residue are used to generate a novel metapath. Such a path filtering is particularly recommended if some information on allosteric residues is available. The selection syntax for a residue pair ("Pairs") is C:C:c534,A:A:?600 (the lower-case "c" stands for cytosine and "?" indicates any non standard amino acid or nucleotide residue). Selection of more than one apical residue pair has the following syntax: C:C:c534,A:A:?600,C:C:c534,A:A:E41. Only one residue can be selected as a tail ("Tail"). For midway residue(s), each residue must be separated by a comma as well e.g. A:A:?600,A:A:E41.

Midway



Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.


2D representation of the interactions of this orthosteric/allosteric ligand.


Node1Node2OwnerNet1LinkStrengthNet2LinkStrengthComm1Comm2Node1ShellNode2Shell
2x563x32Shared10.03077.205691121
2x567x42Shared4.545333.922781121
2x577x39Shared6.011333.304721122
2x577x42Shared4.267336.769581121
2x607x39Shared7.683.036621022
2x607x425ht_off4.5033301021
3x323x36Shared3.463673.203611111
3x327x42Shared9.501339.561621111
3x32LigShared13.773712.45161110
3x334x57Shared3.407674.353380012
3x33LigShared6.2073311.97190010
3x36LigShared8.0717.72371110
3x374x53Shared4.693335.490740012
3x375x461Shared4.882333.713660011
3x37Lig5ht_off4.37900010
3x405x50Shared4.742673.09880112
3x406x44Shared8.334.104680112
5x445x48Shared4.2643.57621112
5x446x52Shared3.7154.189721111
5x44Lig5ht_off3.3206701110
5x475x48Shared8.819676.111531122
5x476x52Shared30.18421.20091121
5x486x56Shared3.8934.066061122
6x446x48Shared4.376674.20870121
6x447x455ht_off8.1086700122
6x486x515ht_off7.8513301111
6x486x52Shared5.911336.097271111
6x487x41Shared12.4357.697681112
6x48Lig5ht_off13.83801110
6x516x52Shared9.218333.107361111
6x517x345ht_off4.00501112
6x517x38Shared6.204335.077781111
6x51LigShared13.797311.05671110
6x52LigShared12.86637.752821110
7x387x42Shared5.475338.486531111
7x38LigShared5.0722.761111110
7x397x42Shared8.3917.252921121
7x42Lig5ht_off4.41801110
3x40Lig5ht_off3.8053300110
5x486x525ht_off3.8083301121
6x516x55Shared3.2623.148191111
E2x52LigShared3.073333.537820010
5x406x55Shared2.4362.044170021
5x43LigShared2.1294.924860010
5x461Lig5ht_on_gp02.849540010
3x29E2x525ht_on_gp04.705140021
3x366x485ht_on_gp04.984491111
3x374x565ht_on_gp03.610012
3x406x485ht_on_gp05.567820111
5x395x435ht_on_gp06.806201121
5x446x565ht_on_gp02.898061112
5x476x445ht_on_gp04.671341122
5x476x485ht_on_gp03.042961121
6x487x455ht_on_gp09.80381112
6x55Lig5ht_on_gp07.184210110

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Difference Members
Id Description
5ht_on_gp 5ht1_on_gp
5ht2_on_gp
5ht4_on_gp
5ht5_on_gp
5ht6_on_gp
5ht7_on_gp
5ht_off 5ht2_off
5ht1_off
Network Difference
Value 5ht_on_gp 5ht_off
Imin 2.6794 3.30567
Number of Linked Nodes 951 275
Number of Specific Nodes 681 (71.61%) 5  (1.82%)
Number of Shared Nodes 270 (28.39%) 270  (98.18%)
Number of Links 1117 303
Number of Specific Links 949 (84.96%) 135  (44.55%)
Number of Shared Links 168 (15.04%) 168  (55.45%)
Number of Hubs 167 34
Number of Specific Hubs 146 (87.43%) 13  (38.24%)
Number of Shared Hubs 21 (12.57%) 21  (61.76%)
Average % Shared Neighbours (Jaccard) 12.38
Average % Shared Neighbours (Otsuka) 15.19
Average % Shared Neighbours (Overlap Coefficient) 18.07
Average % Shared Cliques (k3-6) 51.48
Graphlets Similarity 0.648483
Paths Difference
Value 5ht_on_gp 5ht_off
Number Of Nodes in MetaPath 95 89
Specific Nodes in MetaPath 81 (85.26%) 75  (84.27%)
Shared Nodes in MetaPath 270 (28.39%) 270  (28.39%)
Number Of Links MetaPath 101 94
Specific Links in MetaPath 96 (95.05%) 89  (94.68%)
Shared Links in MetaPath 168 (15.04%) 168  (15.04%)
Number of Shortest Paths 5594520 62345
Length Of Smallest Path 3 3
Average Path Length 45.7121 14.1387
Length of Longest Path 76 36
Minimum Path Strength 0.138472 0.3725
Average Path Strength 4.74179 5.30871
Maximum Path Strength 21.1462 21.5252
Minimum Path Correlation 0.701204 0.701667
Average Path Correlation 0.987007 0.915627
Maximum Path Correlation 1 0.99
Minimum % Of Corr. Nodes 1.42857 3.22581
Average % Of Corr. Nodes 23.3399 43.9021
Maximum % Of Corr. Nodes 100 100
Minimum Path Hubs % 0 0
Average Path Hubs % 53.7811 41.6957
Maximum Path Hubs % 100 100

Details about the values in these tables can be found in the corresponding documentation page .

You can download a compressed (zip) file with structure(s), 3D outputs (as PyMol and VMD scripts) and numerical data files (as csv and plain text files).

Download 5ht_off_on_gp.zip<



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