Orange: nodes, hubs and links specific of a2_on_gp network

Green: nodes, hubs and links shared by both networks

Purple: nodes, hubs and links specific of a2_off network

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Owner: the name of the network the hub belong to or "Shared" if the corresponding hub is present in both networks.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub in the corresponding network.

Num Of Links: the number of links of the corresponding hub in the corresponding network.

ConSurf: this column reports the ConSurf conservation grades of each hub.


Index Hub Owner a2_on_gp Avg Int. Strength a2_off Avg Int. Strength a2_on_gp Num Of Links a2_off Num Of Links ConSurf
1G.HN.29 a2_on_gp00402
2G.H1.01 a2_on_gp500509
3G.S2.03 a2_on_gp250409
4G.S2.06 a2_on_gp00409
5G.S2.08 a2_on_gp00406
6G.S3.01 a2_on_gp500405
7G.S3.03 a2_on_gp1000508
8G.S3.06 a2_on_gp750407
9G.s3h2.03 a2_on_gp750409
10G.H2.01 a2_on_gp250409
11G.H2.06 a2_on_gp500509
12G.H2.07 a2_on_gp1000609
13G.h2s4.01 a2_on_gp1000409
14G.h2s4.05 a2_on_gp250408
15G.S4.03 a2_on_gp00407
16G.S4.07 a2_on_gp250408
17G.s4h3.03 a2_on_gp00408
18G.s4h3.04 a2_on_gp750408
19G.H3.01 a2_on_gp250509
20G.H3.09 a2_on_gp1000509
21G.H3.13 a2_on_gp1000606
22G.H3.17 a2_on_gp500505
23G.S5.03 a2_on_gp250409
24G.S5.05 a2_on_gp1000609
25G.hgh4.05 a2_on_gp750406
26G.hgh4.11 a2_on_gp500605
27G.hgh4.20 a2_on_gp250403
28G.H4.03 a2_on_gp250404
29G.H4.08 a2_on_gp250403
30G.H4.10 a2_on_gp250407
31G.H4.12 a2_on_gp1000404
32G.H4.14 a2_on_gp00405
33G.H4.15 a2_on_gp1000408
34G.h4s6.12 a2_on_gp250402
35G.S6.02 a2_on_gp500408
36G.s6h5.01 a2_on_gp250409
37G.s6h5.02 a2_on_gp00408
38G.s6h5.05 a2_on_gp500509
39G.H5.08 a2_on_gp1000608
40G.H5.13 a2_on_gp00408
41G.H5.17 a2_on_gp750505
42G.H5.19 a2_on_gp250408
43b.1x4 a2_on_gp00408
44b.lhb1x3 a2_on_gp250502
45b.lhb1x6 a2_on_gp500403
46b.b1x3 a2_on_gp250407
47b.b1x6 a2_on_gp500409
48b.l1x3 a2_on_gp1000609
49b.l1x6 a2_on_gp750509
50b.b2x1 a2_on_gp1000508
51b.b2x3 a2_on_gp500406
52b.b2x5 a2_on_gp750607
53b.l2x5 a2_on_gp250405
54b.b3x1 a2_on_gp500405
55b.l3x1 a2_on_gp500409
56b.l3x2 a2_on_gp750509
57b.b4x2 a2_on_gp500408
58b.b4x6 a2_on_gp1000609
59b.b5x3 a2_on_gp500509
60b.b5x5 a2_on_gp500405
61b.l5x1 a2_on_gp1000408
62b.l5x5 a2_on_gp1000609
63b.b6x1 a2_on_gp500409
64b.b6x5 a2_on_gp500406
65b.l7x5 a2_on_gp00406
66b.b8x4 a2_on_gp1000406
67b.l9x3 a2_on_gp1000509
68b.l9x6 a2_on_gp1000508
69b.b10x5 a2_on_gp250509
70b.b11x4 a2_on_gp500509
71b.l11x2 a2_on_gp1000409
72b.b12x6 a2_on_gp1000708
73b.b13x7 a2_on_gp1000507
74b.l13x3 a2_on_gp1000609
75b.l13x6 a2_on_gp500509
76b.l13x7 a2_on_gp750509
77b.l15x1 a2_on_gp250407
78b.l15x2 a2_on_gp500409
79b.b16x4 a2_on_gp750406
80b.b16x6 a2_on_gp1000708
81b.b16x7 a2_on_gp00409
82b.b17x7 a2_on_gp250408
83b.l17x3 a2_on_gp1000509
84b.l17x6 a2_on_gp500409
85b.b18x3 a2_on_gp750408
86b.l18x1 a2_on_gp1000606
87b.l18x2 a2_on_gp500407
88b.l18x3 a2_on_gp750405
89b.b19x2 a2_on_gp1000506
90b.b19x4 a2_on_gp500408
91b.b20x4 a2_on_gp1000508
92b.b20x6 a2_on_gp1000506
93b.b20x7 a2_on_gp250409
94b.l20x2 a2_on_gp500509
95b.b21x1 a2_on_gp750407
96b.b21x2 a2_on_gp00406
97b.b21x7 a2_on_gp1000605
98b.l21x2 a2_on_gp00404
99b.b22x5 a2_on_gp1000607
100b.l22x5 a2_on_gp750509
101b.b23x6 a2_on_gp1000607
102b.l23x1 a2_on_gp500406
103b.b24x6 a2_on_gp500408
104b.b24x7 a2_on_gp500409
105b.l24x2 a2_on_gp250506
106b.l24x3 a2_on_gp250405
107b.l25x3 a2_on_gp1000409
108b.l25x6 a2_on_gp750508
109b.l26x1 a2_on_gp500407
110b.l27x1 a2_on_gp1000609
111b.l27x2 a2_on_gp750409
112b.b28x3 a2_on_gp250407
113b.b28x4 a2_on_gp1000506
114b.b28x6 a2_on_gp750509
115b.b28x7 a2_on_gp250409
116g.l1x4 a2_on_gp250408
117g.ctx3 a2_on_gp1000609
118g.ctx6 a2_on_gp250606
119g.ctx14 a2_on_gp500409
120g.ctx15 a2_on_gp500409
121g.ctx16 a2_on_gp1000808
1221x35 a2_on_gp7550536
1232x46 a2_on_gp1003.84615419
1242x50 a2_on_gp10023.0769539
1253x43 a2_on_gp250439
126I2x51 a2_on_gp500416
1274x38 a2_on_gp250437
1284x56 a2_on_gp5011.5385434
1294x60 a2_on_gp7523.0769434
1304x61 a2_on_gp500525
1315x43 a2_on_gp2526.9231435
1325x58 a2_on_gp1007.69231439
1335x62 a2_on_gp00435
1345x69 a2_on_gp250424
1356x30 a2_on_gp00527
1367x49 a2_on_gp7523.0769439
1377x55 a2_on_gp250516
1381x39 Shared7596.1538556
1391x50 Shared503.84615549
140I1x50 Shared7596.1538658
1412x42 Shared7546.1538548
1422x57 Shared10088.4615556
1433x37 Shared75100555
1443x50 Shared2557.6923459
145I2x53 Shared10088.4615566
146E2 Shared10010016174
147E2x52 Shared1007.69231544
1485x39 Shared100100576
1495x40 Shared10061.5385544
1505x42 Shared011.5385443
1515x44 Shared10042.3077556
1526x44 Shared50100459
1536x48 Shared10076.9231647
1546x52 Shared5069.2308447
155E3 Shared7576.9231652
1567x42 Shared7534.6154647
1577x53 Shared100100559
1588x50 Shared100100768
159Lig Shared10010013100
1601x60 a2_off0100246
1612x40 a2_off5065.3846349
162E1x50 a2_off069.2308346
1633x31 a2_off073.0769344
1643x41 a2_off2511.5385345
1653x49 a2_off2580.7692349
1663x54 a2_off250348
167I2x57 a2_off065.3846257
1684x50 a2_off500349
1694x59 a2_off03.84615346
1705x45 a2_off2576.9231145
1715x461 a2_off00246
1726x24 a2_off00140
1736x59 a2_off2596.1538344
1746x60 a2_off5080.7692344
1757x33 a2_off03.84615145
1767x56 a2_off015.3846247
1778x49 a2_off2515.3846347
   
Orange: nodes, hubs and links specific of a2_on_gp network

Green: nodes, hubs and links shared by both networks

Purple: nodes, hubs and links specific of a2_off network

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Owner: the name of the network the link belong to or "Shared" if the corresponding link is present in both networks.

Recurrence: the relative Recurrence in the filtered pool of shortest paths.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.


Index Node1 Node2 Owner a2_on_gp Recurrence a2_off Recurrence a2_on_gp Hub1? a2_off Hub1? a2_on_gp Hub2? a2_off Hub2? ConSurf1 ConSurf2
1b.l26x5 g.ctx4 a2_on_gp98.4880NoNoNoNo57
2g.ctx3 g.ctx4 a2_on_gp98.5210YesNoNoNo97
3g.ctx3 g.ctx5 a2_on_gp99.78620YesNoNoNo99
4b.lhb1x11 g.ctx5 a2_on_gp99.81340NoNoNoNo49
5b.b25x7 b.lhb1x11 a2_on_gp99.89420NoNoNoNo74
6b.b25x7 b.b28x6 a2_on_gp1000NoNoYesNo79
7b.b27x3 b.b28x6 a2_on_gp49.78060NoNoYesNo89
8b.b27x3 b.l25x3 a2_on_gp49.75810NoNoYesNo89
9b.l25x3 b.l27x2 a2_on_gp99.37630YesNoYesNo99
10b.l25x4 b.l27x2 a2_on_gp99.61620NoNoYesNo59
11I1x49 b.l25x4 a2_on_gp99.1480NoNoNoNo65
12I1x49 I1x50 a2_on_gp99.05290NoNoYesYes68
132x40 I1x50 a2_on_gp96.0511.87206NoYesYesYes98
142x39 I2x53 a2_on_gp44.22160NoNoYesYes96
15G.H5.19 I2x53 a2_on_gp43.68540YesNoYesYes86
16G.H5.15 G.H5.19 a2_on_gp43.39210NoNoYesNo88
17G.H5.15 G.h2s4.05 a2_on_gp36.75470NoNoYesNo88
18b.b28x4 b.b28x6 a2_on_gp50.20170YesNoYesNo69
19b.b28x4 b.l25x3 a2_on_gp49.85420YesNoYesNo69
20b.b2x3 b.b2x5 a2_on_gp89.10660YesNoYesNo67
21b.b26x2 b.b2x3 a2_on_gp90.53270NoNoYesNo76
22b.b26x1 b.b26x2 a2_on_gp90.48430NoNoNoNo97
23b.b26x1 b.l27x1 a2_on_gp90.43650NoNoYesNo99
24b.l3x1 b.l5x5 a2_on_gp11.85180YesNoYesNo99
25G.S3.06 b.l5x5 a2_on_gp11.81460YesNoYesNo79
26b.b2x1 b.l27x1 a2_on_gp82.44010YesNoYesNo89
27G.S1.04 G.h2s4.05 a2_on_gp26.49210NoNoYesNo78
28G.S1.04 G.S4.03 a2_on_gp26.32480NoNoYesNo77
29b.l25x6 b.l27x1 a2_on_gp12.72880YesNoYesNo89
30G.S4.03 G.S5.05 a2_on_gp25.43680YesNoYesNo79
31G.S5.05 G.s6h5.01 a2_on_gp23.61540YesNoYesNo99
32G.S5.07 G.s6h5.01 a2_on_gp22.27140NoNoYesNo99
33G.S5.07 G.s5hg.01 a2_on_gp21.41170NoNoNoNo99
34G.S4.07 G.s5hg.01 a2_on_gp20.88270YesNoNoNo89
35G.S4.07 G.s4h3.03 a2_on_gp19.81480YesNoYesNo88
36b.b6x1 b.l9x6 a2_on_gp84.09120YesNoYesNo98
37b.b2x1 b.b6x1 a2_on_gp81.57130YesNoYesNo89
38G.H2.06 b.l9x6 a2_on_gp84.16690YesNoYesNo98
39G.H2.06 b.l17x6 a2_on_gp41.91290YesNoYesNo99
40G.s4h3.03 G.s4h3.15 a2_on_gp19.10150YesNoNoNo89
41G.hgh4.01 G.s4h3.15 a2_on_gp18.95480NoNoNoNo69
42G.hgh4.01 G.s4h3.04 a2_on_gp18.77950NoNoYesNo68
43G.HG.15 G.s4h3.04 a2_on_gp18.25260NoNoYesNo78
44G.HG.15 G.hgh4.05 a2_on_gp18.07670NoNoYesNo76
45G.H4.10 G.hgh4.05 a2_on_gp11.54660YesNoYesNo76
46b.l23x1 b.l25x6 a2_on_gp11.45270YesNoYesNo68
472x46 3x43 a2_on_gp28.0160YesNoYesNo99
482x46 3x42 a2_on_gp55.49090YesNoNoNo97
492x45 3x42 a2_on_gp55.62861.34491NoNoNoNo97
502x42 3x49 a2_on_gp58.42530YesYesNoYes89
51b.l17x6 b.l19x1 a2_on_gp42.81230YesNoNoNo99
52b.l17x5 b.l19x1 a2_on_gp84.27260NoNoNoNo69
53b.l17x5 b.l19x2 a2_on_gp84.02980NoNoNoNo69
54b.b20x2 b.l19x2 a2_on_gp83.54390NoNoNoNo69
55b.b20x2 b.b20x4 a2_on_gp83.05750NoNoYesNo68
56b.b20x4 b.l17x3 a2_on_gp22.78820YesNoYesNo89
57b.b19x4 b.l17x3 a2_on_gp21.48080YesNoYesNo89
58b.b18x3 b.b19x4 a2_on_gp42.42210YesNoYesNo88
59b.b14x2 b.b18x3 a2_on_gp63.17120NoNoYesNo78
60b.b10x2 b.b14x2 a2_on_gp62.37680NoNoNoNo67
61b.b10x2 b.b14x3 a2_on_gp48.00120NoNoNoNo65
62b.b11x5 b.b14x3 a2_on_gp47.20490NoNoNoNo65
63b.b11x5 b.l13x7 a2_on_gp45.61230NoNoYesNo69
64b.l13x3 b.l13x7 a2_on_gp24.81020YesNoYesNo99
65b.b16x4 b.l13x3 a2_on_gp11.21290YesNoYesNo69
66G.H2.06 b.b18x1 a2_on_gp41.78610YesNoNoNo99
67b.b18x1 b.l19x1 a2_on_gp41.70320NoNoNoNo99
68b.b20x4 b.b20x6 a2_on_gp59.54340YesNoYesNo86
69b.b19x4 b.b20x6 a2_on_gp21.49310YesNoYesNo86
70b.b19x2 b.b20x6 a2_on_gp21.99860YesNoYesNo66
71b.b18x3 b.b19x2 a2_on_gp21.53990YesNoYesNo86
72b.b17x7 b.b20x6 a2_on_gp15.88330YesNoYesNo86
73b.l21x7 b.l23x1 a2_on_gp11.21190NoNoYesNo56
74b.l21x7 b.l23x2 a2_on_gp11.0490NoNoNoNo58
75b.b10x2 b.b10x4 a2_on_gp13.60060NoNoNoNo66
76b.l26x3 b.l26x5 a2_on_gp93.66590NoNoNoNo75
77b.l26x1 b.l26x3 a2_on_gp93.52390YesNoNoNo77
78b.b2x5 b.l26x1 a2_on_gp93.51690YesNoYesNo77
79b.b10x4 b.b14x5 a2_on_gp12.00310NoNoNoNo65
80b.b14x5 b.l10x1 a2_on_gp11.20440NoNoNoNo53
81b.b12x3 b.l13x7 a2_on_gp10.40570NoNoYesNo89
82b.b13x4 b.b13x5 a2_on_gp11.22220NoNoNoNo44
83b.b17x3 g.h1x10 a2_on_gp12.02760NoNoNoNo59
843x43 6x44 a2_on_gp25.26166.91042YesNoYesYes99
856x48 7x45 a2_on_gp23.59660YesYesNoNo78
867x45 7x49 a2_on_gp24.23150NoNoYesNo89
872x46 7x49 a2_on_gp24.1691.16582YesNoYesNo99
882x37 2x40 Shared96.730767.6714NoNoNoYes89
892x37 2x39 Shared96.533666.1339NoNoNoNo89
902x45 4x46 Shared56.315342.3039NoNoNoNo97
912x42 4x46 Shared56.45341.1854YesYesNoNo87
922x39 3x49 Shared52.213246.8016NoNoNoYes99
936x48 Lig Shared37.694872.8821YesYesYesYes70
946x44 6x48 Shared24.505474.2608YesYesYesYes97
95E2 Lig Shared14.356832.6429YesYesYesYes40
961x39 2x61 a2_off2.0447612.7023YesYesNoNo67
971x36 2x61 a2_off1.3632911.4453NoNoNoNo77
981x39 7x42 a2_off4.7652125.5533YesYesYesYes67
997x38 7x42 a2_off0.0011559633.8222NoNoYesYes57
1007x38 Lig a2_off2.0619634.8528NoNoYesYes50
1013x39 6x44 a2_off0100NoNoYesYes99
1023x39 Na1 a2_off099.9696NoNoNoNo90
1032x50 Na1 a2_off099.973YesNoNoNo90
1042x50 7x46 a2_off0.91919423.0291YesNoNoNo99
1051x50 2x50 a2_off2.3890397.6244YesYesYesNo99
1061x50 7x50 a2_off0.18461496.827YesYesNoNo99
1071x53 7x50 a2_off095.9213NoNoNoNo99
1081x53 7x53 a2_off095.6273NoNoYesYes99
1097x53 8x50 a2_off055.9355YesYesYesYes98
1108x50 8x54 a2_off012.3712YesYesNoNo86
1111x52 8x54 a2_off010.4586NoNoNoNo66
1128x50 I1x50 a2_off2.2846610.7931YesYesYesYes88
1132x43 7x53 a2_off033.1937NoNoYesYes89
1142x40 2x43 a2_off032.6293NoYesNoNo98
1152x40 8x50 a2_off0.77789434.7853NoYesYesYes98
1163x49 I2x57 a2_off032.0583NoYesNoYes97
1172x38 I2x57 a2_off020.7853NoNoNoYes67
1182x39 3x50 a2_off017.7745NoNoYesYes99
1195x42 E2 a2_off0.7332217.7373YesYesYesYes34
1205x42 5x461 a2_off020.9644YesYesNoYes36
1213x37 5x461 a2_off0.34209721.032YesYesNoYes56
1223x37 4x53 a2_off049.3765YesYesNoNo57
1233x38 4x53 a2_off0.1895148.873NoNoNoNo77
1243x38 4x50 a2_off0.37895147.7951NoNoNoYes79
1252x45 4x50 a2_off0.75742744.5207NoNoNoYes99
1263x40 6x44 a2_off044.8282NoNoYesYes79
1273x37 3x40 a2_off3.7058842.2465YesYesNoNo57
1282x42 3x46 a2_off037.7657YesYesNoNo89
1292x53 7x46 a2_off016.8249NoNoNoNo69
1302x53 3x35 a2_off013.5809NoNoNoNo66
1313x31 3x35 a2_off2.0712811.3844NoYesNoNo46
1326x52 Lig a2_off4.1238616.7776YesYesYesYes70
1333x46 6x37 a2_off036.6201NoNoNoNo98
1345x58 6x37 a2_off035.4408YesNoNoNo98
1353x47 5x58 a2_off033.2612NoNoYesNo99
1363x49 I2x53 a2_off6.3524913.4626NoYesYesYes96
1373x50 I2x53 a2_off013.3444YesYesYesYes96
1383x47 5x57 a2_off032.0887NoNoNoNo97
1395x57 5x61 a2_off6.4687630.9093NoNoNoNo79
1403x52 I2x53 a2_off016.9094NoNoYesYes66
1413x54 5x61 a2_off2.176222.4411NoYesNoNo89
1423x52 3x56 a2_off020.4609NoNoNoNo65
1433x56 I2x52 a2_off0.89831810.2423NoNoNoNo55
1442x38 4x39 a2_off017.3994NoNoNoNo62
1455x37 6x59 a2_off010.1037NoNoNoYes34
1465x44 6x52 a2_off3.4474215.5544YesYesYesYes67
1476x40 7x53 a2_off0.84711619.2546NoNoYesYes89
1486x40 7x52 a2_off018.3624NoNoNoNo88
1496x39 7x52 a2_off0.72397214.0777NoNoNoNo78
1506x39 7x56 a2_off0.54316612.9862NoNoNoYes77
1513x54 5x68 a2_off013.9019NoYesNoNo87
1525x68 6x27 a2_off011.5906NoNoNoNo74
1532x41 4x39 a2_off010.5194NoNoNoNo52

Here, those paths that begin and end at given residue pair(s) or that pass through a residue are used to generate a novel metapath. Such a path filtering is particularly recommended if some information on allosteric residues is available. The selection syntax for a residue pair ("Pairs") is C:C:c534,A:A:?600 (the lower-case "c" stands for cytosine and "?" indicates any non standard amino acid or nucleotide residue). Selection of more than one apical residue pair has the following syntax: C:C:c534,A:A:?600,C:C:c534,A:A:E41. Only one residue can be selected as a tail ("Tail"). For midway residue(s), each residue must be separated by a comma as well e.g. A:A:?600,A:A:E41.

Midway



Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.


2D representation of the interactions of this orthosteric/allosteric ligand.


Node1Node2OwnerNet1LinkStrengthNet2LinkStrengthComm1Comm2Node1ShellNode2Shell
1x351x39Shared15.538516.5550222
1x392x57Shared7.252317.1755222
1x397x42Shared12.830410.77255221
2x577x42Shared10.35086.965221
E1x51E2Shared13.86461.61750021
3x22E2Shared14.841223.8550021
3x25E2Shared4.467315.1251221
3x26E2Shared14.456511.02250221
3x335x39Shared3.699233.51751222
3x335x43a2_off7.2901221
3x366x48Shared5.318463.03250211
3x373x40Shared4.3254.121222
3x406x44a2_off5.7469200022
4x605x39Shared16.529613.56251222
5x36E2Shared18.913810.2551021
5x38E2Shared9.518082.1651021
5x39E2Shared13.466510.5551221
E2E2Shared77.38514.461211
E2E2x51Shared13.786913.76751212
E2E2x52Shared13.948511.3951211
5x40E2x52Shared6.744234.04251211
E2x52LigShared34.757331.851210
5x365x38a2_off4.7646101022
5x376x55Shared7.334235.60751021
5x395x40a2_off3.7284601221
5x395x42Shared9.680779.54251222
5x395x43a2_off7.6923101221
5x40LigShared4.892698.07751210
5x445x47Shared3.426154.5851222
5x446x52Shared24.889217.821221
5x476x52Shared6.494238.99251221
6x446x48Shared14.841212.0250021
6x447x45a2_off8.1807700022
6x487x41Shared9.773855.250212
6x51LigShared15.23544.53250010
6x547x34Shared3.366153.0402021
6x55LigShared10.35657.18250210
6x58E3Shared10.31962.56250021
6x61E3Shared10.185.81502021
7x34E3a2_off4.9938501011
7x34LigShared4.966924.33251010
7x387x42Shared4.030394.64250211
7x38LigShared10.168510.820210
1x352x64Shared4.258085.7250221
3x23E2Shared7.692.97751021
3x335x40Shared3.534623.181221
5x42E2Shared6.286153.511221
5x37E2a2_off4.2669201021
E2E3a2_off8.4761501211
E2LigShared6.943083.821210
5x436x52Shared3.485393.511211
6x48LigShared4.333083.510210
6x52LigShared5.533085.08251210
E3Liga2_off5.34269012010
6x517x37Shared3.090772.5450012
2x66E2x51a2_off3.0253800022
3x29E2x52Shared2.876923.11750021
2x607x42Shared2.816921.82750021
4x63E2a2_off2.2200021
1x357x38a2_on_gp06.95250221
3x33E2x52a2_on_gp03.35251221
3x36Liga2_on_gp08.3550210
3x375x43a2_on_gp04.291221
3x406x48a2_on_gp012.33250021
5x406x55a2_on_gp03.5051211
6x487x45a2_on_gp09.32250212
6x517x41a2_on_gp03.63750012
E3E3a2_on_gp08.067512011
7x30E3a2_on_gp05.857562021
7x417x42a2_on_gp02.7850021
7x42Liga2_on_gp04.85755210
2x64Liga2_on_gp03.94750010
4x60E2a2_on_gp03.22251221
5x405x43a2_on_gp03.1551211
5x43Liga2_on_gp05.31210
6x54E3a2_on_gp01.902021
2x66E2a2_on_gp01.3050021

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Difference Members
Id Description
a2_on_gp a2b_on_gp
a2_off a2a_off
Network Difference
Value a2_on_gp a2_off
Imin 2.7825 3.35231
Number of Linked Nodes 888 271
Number of Specific Nodes 633 (71.28%) 16  (5.90%)
Number of Shared Nodes 255 (28.72%) 255  (94.10%)
Number of Links 1051 307
Number of Specific Links 886 (84.30%) 142  (46.25%)
Number of Shared Links 165 (15.70%) 165  (53.75%)
Number of Hubs 159 40
Number of Specific Hubs 137 (86.16%) 18  (45.00%)
Number of Shared Hubs 22 (13.84%) 22  (55.00%)
Average % Shared Neighbours (Jaccard) 12.22
Average % Shared Neighbours (Otsuka) 15.10
Average % Shared Neighbours (Overlap Coefficient) 18.11
Average % Shared Cliques (k3-6) 77.27
Graphlets Similarity 0.669638
Paths Difference
Value a2_on_gp a2_off
Number Of Nodes in MetaPath 94 65
Specific Nodes in MetaPath 81 (86.17%) 52  (80.00%)
Shared Nodes in MetaPath 255 (28.72%) 255  (28.72%)
Number Of Links MetaPath 95 66
Specific Links in MetaPath 87 (91.58%) 58  (87.88%)
Shared Links in MetaPath 165 (15.70%) 165  (15.70%)
Number of Shortest Paths 2115768 55987
Length Of Smallest Path 3 3
Average Path Length 41.7519 16.7498
Length of Longest Path 80 41
Minimum Path Strength 0.36 0.269808
Average Path Strength 5.65771 6.26313
Maximum Path Strength 21.335 21.7265
Minimum Path Correlation 0.7025 0.701154
Average Path Correlation 0.977919 0.922956
Maximum Path Correlation 1 0.99
Minimum % Of Corr. Nodes 1.33333 2.85714
Average % Of Corr. Nodes 32.6228 40.6574
Maximum % Of Corr. Nodes 100 100
Minimum Path Hubs % 0 0
Average Path Hubs % 46.2902 40.1791
Maximum Path Hubs % 100 100

Details about the values in these tables can be found in the corresponding documentation page .

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