Orange: nodes, hubs and links specific of adenosine_on_gp network

Green: nodes, hubs and links shared by both networks

Purple: nodes, hubs and links specific of adenosine_off network

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Owner: the name of the network the hub belong to or "Shared" if the corresponding hub is present in both networks.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub in the corresponding network.

Num Of Links: the number of links of the corresponding hub in the corresponding network.

ConSurf: this column reports the ConSurf conservation grades of each hub.


Index Hub Owner adenosine_on_gp Avg Int. Strength adenosine_off Avg Int. Strength adenosine_on_gp Num Of Links adenosine_off Num Of Links ConSurf
1g.h1x1 adenosine_on_gp00402
2g.h1x8 adenosine_on_gp00407
3g.h1x11 adenosine_on_gp00409
4g.l1x4 adenosine_on_gp33.33330408
5g.h2x11 adenosine_on_gp500406
6g.ctx3 adenosine_on_gp1000509
7g.ctx6 adenosine_on_gp41.66670606
8g.ctx14 adenosine_on_gp500409
9g.ctx16 adenosine_on_gp1000708
102x40 adenosine_on_gp66.666732.6923538
112x46 adenosine_on_gp83.33330429
123x33 adenosine_on_gp66.66670434
133x35 adenosine_on_gp33.33330437
143x40 adenosine_on_gp33.33330438
154x50 adenosine_on_gp00539
164x56 adenosine_on_gp16.66670435
174x60 adenosine_on_gp750434
18E2x52 adenosine_on_gp66.66670434
195x42 adenosine_on_gp505.76923435
205x58 adenosine_on_gp83.33330539
215x66 adenosine_on_gp00425
226x29 adenosine_on_gp00426
236x51 adenosine_on_gp33.33330426
247x38 adenosine_on_gp66.66670425
257x39 adenosine_on_gp33.33330435
268x48 adenosine_on_gp00434
27G.S1.05 adenosine_on_gp33.33330409
28G.H1.01 adenosine_on_gp33.33330509
29G.S2.03 adenosine_on_gp8.333330509
30G.S2.05 adenosine_on_gp00503
31G.S2.06 adenosine_on_gp00408
32G.S2.08 adenosine_on_gp500405
33G.S3.03 adenosine_on_gp1000507
34G.S3.04 adenosine_on_gp33.33330407
35G.S3.06 adenosine_on_gp91.66670506
36G.H2.06 adenosine_on_gp83.33330509
37G.H2.07 adenosine_on_gp1000609
38G.h2s4.01 adenosine_on_gp1000409
39G.S4.02 adenosine_on_gp500507
40G.S4.04 adenosine_on_gp33.33330509
41G.s4h3.04 adenosine_on_gp91.66670608
42G.H3.09 adenosine_on_gp83.33330609
43G.H3.13 adenosine_on_gp66.66670606
44G.H3.17 adenosine_on_gp83.33330605
45G.H3.18 adenosine_on_gp33.33330409
46G.S5.05 adenosine_on_gp66.66670409
47G.S5.07 adenosine_on_gp33.33330409
48G.s5hg.01 adenosine_on_gp500409
49G.HG.04 adenosine_on_gp66.66670408
50G.HG.14 adenosine_on_gp00405
51G.HG.15 adenosine_on_gp33.33330407
52G.hgh4.02 adenosine_on_gp66.66670508
53G.hgh4.05 adenosine_on_gp91.66670406
54G.H4.10 adenosine_on_gp41.66670506
55G.H4.12 adenosine_on_gp33.33330405
56G.H4.15 adenosine_on_gp83.33330408
57G.h4s6.02 adenosine_on_gp33.33330407
58G.S6.02 adenosine_on_gp500508
59G.S6.05 adenosine_on_gp00405
60G.H5.08 adenosine_on_gp1000508
61G.H5.13 adenosine_on_gp00407
62G.H5.17 adenosine_on_gp58.33330705
63G.H5.20 adenosine_on_gp00408
64G.H5.26 adenosine_on_gp66.66670407
65b.1x1 adenosine_on_gp00404
66b.1x15 adenosine_on_gp00407
67b.lhb1x6 adenosine_on_gp00403
68b.b1x3 adenosine_on_gp00407
69b.l1x3 adenosine_on_gp1000609
70b.l1x6 adenosine_on_gp250509
71b.b2x1 adenosine_on_gp1000608
72b.b2x3 adenosine_on_gp66.66670406
73b.b2x5 adenosine_on_gp91.66670607
74b.l3x1 adenosine_on_gp16.66670409
75b.l3x2 adenosine_on_gp750509
76b.b4x3 adenosine_on_gp33.33330407
77b.b4x6 adenosine_on_gp1000609
78b.b5x2 adenosine_on_gp00407
79b.b5x3 adenosine_on_gp83.33330709
80b.b5x7 adenosine_on_gp500507
81b.l5x1 adenosine_on_gp1000508
82b.l5x5 adenosine_on_gp1000609
83b.b6x5 adenosine_on_gp66.66670506
84b.b7x1 adenosine_on_gp66.66670504
85b.b7x4 adenosine_on_gp33.33330408
86b.l7x5 adenosine_on_gp00406
87b.b8x4 adenosine_on_gp1000406
88b.l9x3 adenosine_on_gp1000609
89b.l9x6 adenosine_on_gp1000708
90b.b10x3 adenosine_on_gp00408
91b.b10x5 adenosine_on_gp41.66670609
92b.l10x1 adenosine_on_gp00503
93b.b11x4 adenosine_on_gp83.33330409
94b.l11x2 adenosine_on_gp66.66670409
95b.b12x6 adenosine_on_gp1000608
96b.b13x7 adenosine_on_gp1000507
97b.l13x3 adenosine_on_gp1000609
98b.l13x7 adenosine_on_gp750409
99b.b15x2 adenosine_on_gp66.66670406
100b.l15x2 adenosine_on_gp66.66670509
101b.b16x4 adenosine_on_gp750406
102b.b16x6 adenosine_on_gp1000708
103b.b17x7 adenosine_on_gp750408
104b.l17x3 adenosine_on_gp1000709
105b.l17x6 adenosine_on_gp500409
106b.b18x3 adenosine_on_gp91.66670508
107b.b18x5 adenosine_on_gp66.66670405
108b.l18x1 adenosine_on_gp1000706
109b.l18x2 adenosine_on_gp83.33330407
110b.b19x2 adenosine_on_gp1000606
111b.b19x4 adenosine_on_gp66.66670408
112b.l19x2 adenosine_on_gp33.33330509
113b.b20x4 adenosine_on_gp1000508
114b.b20x6 adenosine_on_gp1000606
115b.b20x7 adenosine_on_gp750409
116b.l20x2 adenosine_on_gp500409
117b.b21x1 adenosine_on_gp91.66670407
118b.b21x2 adenosine_on_gp00406
119b.b21x3 adenosine_on_gp00406
120b.b21x7 adenosine_on_gp83.33330605
121b.l21x2 adenosine_on_gp00404
122b.b22x5 adenosine_on_gp1000607
123b.l22x5 adenosine_on_gp91.66670509
124b.b23x2 adenosine_on_gp00406
125b.b23x6 adenosine_on_gp1000707
126b.b24x4 adenosine_on_gp33.33330406
127b.b24x6 adenosine_on_gp83.33330408
128b.l24x3 adenosine_on_gp41.66670505
129b.l25x3 adenosine_on_gp1000409
130b.l27x1 adenosine_on_gp1000809
131b.l27x2 adenosine_on_gp91.66670409
132b.b28x2 adenosine_on_gp33.33330404
133b.b28x4 adenosine_on_gp66.66670406
134b.b28x6 adenosine_on_gp91.66670509
135G.HN.29 adenosine_on_gp00400
1361x35 Shared91.666725545
1371x39 Shared7548.0769556
1381x60 Shared050446
139I1x50 Shared2548.0769458
1402x42 Shared58.333323.0769548
1412x50 Shared10025549
1422x57 Shared66.666794.2308466
1433x37 Shared75100456
1443x49 Shared040.3846459
1453x50 Shared41.666778.8462459
1463x53 Shared66.666750648
147I2x53 Shared10044.2308557
148E2 Shared10010018183
1495x39 Shared83.3333100676
1505x40 Shared10080.7692665
1515x44 Shared10071.1538455
1525x461 Shared66.666750548
1536x30 Shared00446
1546x44 Shared16.6667100459
1556x48 Shared10063.4615658
1566x59 Shared5073.0769444
157E3 Shared7538.4615763
1587x35 Shared500443
1597x42 Shared7550547
1607x49 Shared7525449
1617x53 Shared10075569
1628x50 Shared10075569
163Lig Shared10010011120
1641x50 adenosine_off33.33330349
1651x55 adenosine_off00144
166E1x50 adenosine_off00243
1673x31 adenosine_off036.5385344
1683x54 adenosine_off00359
169I2x52 adenosine_off00245
1706x24 adenosine_off00140
1717x45 adenosine_off025349
1727x56 adenosine_off00247
   
Orange: nodes, hubs and links specific of adenosine_on_gp network

Green: nodes, hubs and links shared by both networks

Purple: nodes, hubs and links specific of adenosine_off network

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Owner: the name of the network the link belong to or "Shared" if the corresponding link is present in both networks.

Recurrence: the relative Recurrence in the filtered pool of shortest paths.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.


Index Node1 Node2 Owner adenosine_on_gp Recurrence adenosine_off Recurrence adenosine_on_gp Hub1? adenosine_off Hub1? adenosine_on_gp Hub2? adenosine_off Hub2? ConSurf1 ConSurf2
1b.l13x3 b.l13x7 adenosine_on_gp11.73630YesNoYesNo99
2b.b11x5 b.l13x7 adenosine_on_gp14.40030NoNoYesNo69
3b.b11x5 b.b14x3 adenosine_on_gp14.82290NoNoNoNo65
4b.b10x2 b.b14x3 adenosine_on_gp15.03550NoNoNoNo65
5b.b10x2 b.b6x2 adenosine_on_gp19.19890NoNoNoNo68
6b.b10x3 b.b6x2 adenosine_on_gp19.40440YesNoNoNo88
7b.b10x3 b.b11x4 adenosine_on_gp23.81130YesNoYesNo89
8b.b11x4 b.l9x3 adenosine_on_gp23.8620YesNoYesNo99
9b.b11x6 b.l9x3 adenosine_on_gp25.88740NoNoYesNo99
10b.b11x6 b.l11x1 adenosine_on_gp26.9390NoNoNoNo99
11b.l11x1 b.l9x6 adenosine_on_gp27.130NoNoYesNo98
12G.H2.06 b.l9x6 adenosine_on_gp19.24270YesNoYesNo98
13G.H2.06 b.l17x6 adenosine_on_gp17.99020YesNoYesNo99
14b.l17x6 b.l19x1 adenosine_on_gp17.65310YesNoNoNo99
15b.l17x5 b.l19x1 adenosine_on_gp17.23460NoNoNoNo69
16b.l17x5 b.l19x2 adenosine_on_gp17.02480NoNoYesNo69
17b.l17x3 b.l19x2 adenosine_on_gp15.03460YesNoYesNo99
18b.b6x1 b.l9x6 adenosine_on_gp25.39620NoNoYesNo98
19b.b2x1 b.b6x1 adenosine_on_gp25.20070YesNoNoNo89
20b.b2x1 b.l27x1 adenosine_on_gp26.17920YesNoYesNo89
21b.l23x1 b.l25x6 adenosine_on_gp36.16480NoNoNoNo68
22b.l21x7 b.l23x1 adenosine_on_gp35.69290NoNoNoNo56
23b.b23x6 b.l21x7 adenosine_on_gp34.66630YesNoNoNo75
24b.b23x6 b.b24x6 adenosine_on_gp14.83670YesNoYesNo78
25b.b21x7 b.b24x6 adenosine_on_gp15.86460YesNoYesNo58
26b.b2x3 b.b2x5 adenosine_on_gp27.29580YesNoYesNo67
27b.b26x2 b.b2x3 adenosine_on_gp43.82830NoNoYesNo76
28b.b26x1 b.b26x2 adenosine_on_gp44.13310NoNoNoNo97
29b.b26x1 b.l27x1 adenosine_on_gp44.44490NoNoYesNo99
30b.b23x1 b.b24x5 adenosine_on_gp10.22570NoNoNoNo55
31b.b24x5 b.b25x5 adenosine_on_gp18.45860NoNoNoNo54
32b.b25x5 b.b25x6 adenosine_on_gp18.6750NoNoNoNo43
33b.b24x4 b.b25x6 adenosine_on_gp18.90380YesNoNoNo63
34b.b23x6 b.b24x4 adenosine_on_gp17.77470YesNoYesNo76
35b.l4x1 g.ctx16 adenosine_on_gp20.83710NoNoYesNo58
36b.b2x5 b.l4x1 adenosine_on_gp21.15180YesNoNoNo75
37b.l4x2 g.ctx16 adenosine_on_gp14.87480NoNoYesNo48
38b.b3x2 b.b4x6 adenosine_on_gp16.05140NoNoYesNo59
39b.b2x3 b.b3x2 adenosine_on_gp15.9080YesNoNoNo65
405x54 6x44 adenosine_on_gp38.27490NoNoYesYes89
415x54 5x58 adenosine_on_gp38.7780NoNoYesNo89
423x50 5x58 adenosine_on_gp40.02250YesYesYesNo99
433x50 G.H5.23 adenosine_on_gp57.7060YesYesNoNo94
443x53 G.H5.23 adenosine_on_gp60.16210YesYesNoNo84
453x53 G.H5.19 adenosine_on_gp76.27130YesYesNoNo87
46G.H5.15 G.H5.19 adenosine_on_gp76.45320NoNoNoNo87
47G.H5.15 I2x51 adenosine_on_gp76.6360NoNoNoNo86
48G.S3.01 I2x51 adenosine_on_gp76.4160NoNoNoNo46
49G.S3.01 G.S3.03 adenosine_on_gp77.05030NoNoYesNo47
50G.S2.06 G.S3.03 adenosine_on_gp96.65680YesNoYesNo87
51G.S2.06 G.S3.05 adenosine_on_gp98.45250YesNoNoNo87
52G.S1.06 G.S3.05 adenosine_on_gp98.77390NoNoNoNo97
53G.H1.01 G.S1.06 adenosine_on_gp98.70290YesNoNoNo99
54G.H1.01 G.s1h1.01 adenosine_on_gp99.84250YesNoNoNo99
55G.S4.04 G.s1h1.01 adenosine_on_gp1000YesNoNoNo99
56G.H3.08 G.S4.04 adenosine_on_gp44.4660NoNoYesNo99
57G.H2.04 G.H3.08 adenosine_on_gp44.45470NoNoNoNo99
58G.H2.04 G.H2.07 adenosine_on_gp44.46330NoNoYesNo99
59G.H2.07 b.l9x6 adenosine_on_gp41.11130YesNoYesNo98
603x36 Lig adenosine_on_gp28.12350NoNoYesYes60
613x36 6x48 adenosine_on_gp28.37171.26293NoNoYesYes68
623x43 7x53 adenosine_on_gp15.45950NoNoYesYes89
633x50 7x53 adenosine_on_gp17.34310YesYesYesYes99
64G.H5.17 G.H5.26 adenosine_on_gp10.2950YesNoYesNo57
65G.H5.17 G.S6.02 adenosine_on_gp11.03060YesNoYesNo58
66G.H5.10 G.S6.02 adenosine_on_gp13.75310NoNoYesNo78
67G.H5.10 G.S5.03 adenosine_on_gp14.29390NoNoNoNo78
68G.S5.03 G.S5.05 adenosine_on_gp14.65340NoNoYesNo89
69G.S4.03 G.S5.05 adenosine_on_gp19.5270NoNoYesNo89
70G.S1.04 G.S4.03 adenosine_on_gp19.80610NoNoNoNo78
71G.S1.04 G.S3.03 adenosine_on_gp20.08530NoNoYesNo77
72b.b23x3 b.b24x5 adenosine_on_gp10.27450NoNoNoNo75
73b.b3x1 b.b6x5 adenosine_on_gp14.26990NoNoYesNo56
74b.b3x1 b.b4x7 adenosine_on_gp14.9910NoNoNoNo58
75b.b4x7 b.l2x5 adenosine_on_gp15.2450NoNoNoNo85
76b.l2x5 b.l4x2 adenosine_on_gp15.5920NoNoNoNo54
77G.H3.12 G.S1.07 adenosine_on_gp25.89080NoNoNoNo89
78G.H3.12 G.S4.04 adenosine_on_gp25.94790NoNoYesNo89
79G.H3.18 G.S4.02 adenosine_on_gp52.5010YesNoYesNo97
80G.H3.17 b.l27x1 adenosine_on_gp24.59760YesNoYesNo59
81G.S4.02 G.S5.02 adenosine_on_gp30.35380YesNoNoNo76
82G.S4.04 G.S4.06 adenosine_on_gp11.8790YesNoNoNo97
83G.H3.09 G.S4.04 adenosine_on_gp36.36370YesNoYesNo99
84G.H4.15 G.S4.06 adenosine_on_gp11.25580YesNoNoNo87
85G.H3.09 G.H4.15 adenosine_on_gp16.95530YesNoYesNo98
86G.H3.06 G.hgh4.02 adenosine_on_gp18.64720NoNoYesNo68
87G.H3.06 G.H4.15 adenosine_on_gp18.95440NoNoYesNo68
88G.H3.15 G.H3.17 adenosine_on_gp52.17730NoNoYesNo85
89b.b3x3 b.b6x5 adenosine_on_gp11.00620NoNoYesNo86
90G.H3.09 G.S5.02 adenosine_on_gp29.24380YesNoNoNo96
91G.H3.15 G.H3.18 adenosine_on_gp52.20850NoNoYesNo89
92G.H3.17 b.l25x6 adenosine_on_gp26.99260YesNoNoNo58
93G.S1.07 G.S4.02 adenosine_on_gp23.40260NoNoYesNo97
946x44 6x48 Shared32.976532.9483YesYesYesYes98
952x50 7x46 Shared11.457491.4655YesYesNoNo99
962x37 2x40 Shared12.867360.0991NoNoYesNo78
97E2 Lig Shared11.429447.0388YesYesYesYes30
981x35 7x35 adenosine_off3.5753614YesYesYesYes53
991x39 2x61 adenosine_off1.5497810.2888YesYesNoNo66
1007x35 Lig adenosine_off022.0819YesYesYesYes30
1013x32 Lig adenosine_off2.53033100NoNoYesYes60
1022x56 3x32 adenosine_off0.5103999.7802NoNoNoNo66
1032x53 2x56 adenosine_off6.5200299.4267NoNoNoNo86
1042x53 7x46 adenosine_off7.6122493.9224NoNoNoNo89
1051x50 2x50 adenosine_off1.834410.7672NoYesYesYes99
1062x50 7x49 adenosine_off7.091782.0991YesYesYesYes99
1077x49 7x53 adenosine_off078.2112YesYesYesYes99
1087x53 8x50 adenosine_off079.8319YesYesYesYes99
1098x50 8x54 adenosine_off014.2069YesYesNoNo97
1101x52 8x54 adenosine_off0.31788911.7931NoNoNoNo77
1118x50 I1x50 adenosine_off010.7328YesYesYesYes98
1122x40 8x50 adenosine_off4.9777658.5819YesNoYesYes89
1132x37 3x53 adenosine_off059.0905NoNoYesYes78
1143x53 I2x53 adenosine_off1.5601221.7716YesYesYesYes87
1155x42 E2 adenosine_off2.4929230.8448YesNoYesYes53
1165x42 5x461 adenosine_off1.5653832.3836YesNoYesYes58
1173x37 5x461 adenosine_off0.025754528.8405YesYesYesYes68
1183x37 4x53 adenosine_off037.2931YesYesNoNo68
1193x38 4x53 adenosine_off0.3094335.3664NoNoNoNo78
1203x38 4x50 adenosine_off0.61867233.431NoNoYesNo79
1212x45 4x50 adenosine_off3.0790729.5345NoNoYesNo99
1222x45 4x46 adenosine_off3.7815927.5733NoNoNoNo98
1232x42 4x46 adenosine_off4.257217.6379YesYesNoNo88
1246x48 Lig adenosine_off053.7586YesYesYesYes80
1253x40 6x44 adenosine_off3.0717429.25YesNoYesYes89
1263x37 3x40 adenosine_off026.8319YesYesYesNo68
1272x42 3x46 adenosine_off011.5647YesYesNoNo89
1282x53 3x35 adenosine_off015.8534NoNoYesNo87
1293x31 3x35 adenosine_off1.1536913.2759NoYesYesNo47
1303x37 3x41 adenosine_off0.63483916.4095YesYesNoNo64
1313x41 4x52 adenosine_off012.3578NoNoNoNo44
132I2x53 I2x57 adenosine_off0.32672514.4569YesYesNoNo77
1333x53 6x30 adenosine_off033.2759YesYesYesYes86
1343x54 6x30 adenosine_off031.9095NoYesYesYes96
1353x54 5x65 adenosine_off010.4914NoYesNoNo98
136I2x56 I2x57 adenosine_off014.694NoNoNoNo47
1376x52 Lig adenosine_off017.7802NoNoYesYes70
1385x44 6x52 adenosine_off0.00056396712.8534YesYesNoNo57
1393x54 5x68 adenosine_off012.4612NoYesNoNo97
1405x68 6x27 adenosine_off010.2198NoNoNoNo71
1416x48 7x45 adenosine_off1.0519918.7845YesYesNoYes89
1427x45 7x48 adenosine_off018.0345NoYesNoNo96
1436x43 7x48 adenosine_off0.32540916.9052NoNoNoNo66
1446x39 6x43 adenosine_off0.97547513.4655NoNoNoNo66
1456x39 7x56 adenosine_off0.6506312.2759NoNoNoYes67
1467x38 7x42 adenosine_off0.011091419.6767YesNoYesYes57
1477x38 Lig adenosine_off4.5623120.6207YesNoYesYes50
1484x48 4x52 adenosine_off0.62280810.319NoNoNoNo14
1492x57 7x42 adenosine_off0.91738611.1681YesYesYesYes67

Here, those paths that begin and end at given residue pair(s) or that pass through a residue are used to generate a novel metapath. Such a path filtering is particularly recommended if some information on allosteric residues is available. The selection syntax for a residue pair ("Pairs") is C:C:c534,A:A:?600 (the lower-case "c" stands for cytosine and "?" indicates any non standard amino acid or nucleotide residue). Selection of more than one apical residue pair has the following syntax: C:C:c534,A:A:?600,C:C:c534,A:A:E41. Only one residue can be selected as a tail ("Tail"). For midway residue(s), each residue must be separated by a comma as well e.g. A:A:?600,A:A:E41.

Midway



Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.


2D representation of the interactions of this orthosteric/allosteric ligand.


Node1Node2OwnerNet1LinkStrengthNet2LinkStrengthComm1Comm2Node1ShellNode2Shell
1x322x64adenosine_off5.3113500022
1x351x39Shared15.344215.624222
1x352x64Shared7.361545.2954222
1x357x35Shared12.240216.764221
1x392x57Shared8.066156.253334222
1x397x42Shared11.647712.61754221
2x563x32Shared4.002314.113330021
2x577x42Shared7.495384.534221
E1x51E2Shared9.047311.289170021
3x213x23adenosine_off4.082501222
3x21E2Shared6.034.208331221
3x22E2Shared24.583123.67830221
3x23E2adenosine_off8.7701021
3x25E2Shared7.321154.271221
3x26E2Shared12.49589.259170221
3x29E2Shared3.423084.848330021
3x32LigShared4.500963.208330010
3x335x39Shared5.074624.10251212
3x335x40Shared3.887314.123331211
3x366x48Shared7.551733.840830011
3x406x44Shared5.698463.76750422
4x594x60Shared3.567124.229171222
4x595x39Shared5.788276.245831222
4x605x39Shared14.872312.17081222
5x36E2Shared14.47197.611221
5x39E2Shared13.910810.191221
5x42E2Shared6.400585.3451221
E2E2Shared74.762551.22331211
E2E2x51Shared10.5867.32751212
E2E2x52Shared12.604210.88331211
5x40E2x52Shared4.617123.004171211
E2x52LigShared38.218732.12171210
E2LigShared7.216545.771671210
5x365x38Shared5.257316.1651222
5x376x55Shared6.472125.375830021
5x376x58adenosine_off3.4736500022
5x395x40Shared4.556733.09251221
5x395x42Shared8.450397.65251222
5x395x43adenosine_off6.1711501222
5x405x43Shared5.014624.1551212
5x406x55Shared4.099423.5051211
5x40LigShared4.238855.570831210
5x445x47Shared4.990584.723331422
5x446x52Shared24.324615.84331421
5x476x52Shared6.707127.664171421
6x446x48Shared15.690612.5251421
6x447x45adenosine_off7.4128901422
6x477x45Shared9.203858.481670422
6x487x41Shared10.77444.81412
6x487x45Shared3.455197.250831412
6x48Ligadenosine_off4.5790401410
6x51LigShared16.62276.79750210
6x547x34Shared3.525582.2166701821
6x55LigShared12.80586.87751210
6x61E3Shared10.964.991670021
7x317x35Shared6.528466.956670021
7x34LigShared4.350965.38250010
7x35Ligadenosine_off5.9057700210
7x387x42Shared4.667694.86250211
7x38LigShared9.5042311.21830210
3x335x43adenosine_off4.332501212
5x38E2adenosine_off5.3040401021
6x52Ligadenosine_off3.4215401410
6x58E3Shared7.412315.404170021
E3Ligadenosine_off3.63135011810
E2E3adenosine_off4.2380801211
6x517x37Shared2.727892.468330212
7x30E3Shared2.15253.6858311821
2x607x42Shared2.140962.559170021
6x57E3Shared1.9251.6983301821
4x63E2Shared1.5351.931670021
1x317x35adenosine_off1.0603800021
1x327x35adenosine_on_gp04.448330021
1x357x38adenosine_on_gp06.950834221
2x593x32adenosine_on_gp02.875835021
2x647x35adenosine_on_gp03.386670221
3x33E2x52adenosine_on_gp03.14751211
3x33Ligadenosine_on_gp03.656671210
3x36Ligadenosine_on_gp010.73330010
3x406x48adenosine_on_gp014.09420421
4x59E2adenosine_on_gp03.031671221
4x60E2adenosine_on_gp03.885831221
6x476x48adenosine_on_gp03.018330421
6x517x38adenosine_on_gp03.458330211
6x517x41adenosine_on_gp05.170830212
6x54E3adenosine_on_gp03.3233301821
E3E3adenosine_on_gp03.697511811
7x42Ligadenosine_on_gp06.345834210
3x223x23adenosine_on_gp03.43750222
3x405x47adenosine_on_gp02.528330422
2x66E2adenosine_on_gp01.908330021

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Difference Members
Id Description
adenosine_on_gp a1_on_gp
a2_on_gp
a3_on_gp
adenosine_off a1_off
a2_off
Network Difference
Value adenosine_on_gp adenosine_off
Imin 2.85917 3.17865
Number of Linked Nodes 904 275
Number of Specific Nodes 638 (70.58%) 9  (3.27%)
Number of Shared Nodes 266 (29.42%) 266  (96.73%)
Number of Links 1065 310
Number of Specific Links 892 (83.76%) 137  (44.19%)
Number of Shared Links 173 (16.24%) 173  (55.81%)
Number of Hubs 163 37
Number of Specific Hubs 135 (82.82%) 9  (24.32%)
Number of Shared Hubs 28 (17.18%) 28  (75.68%)
Average % Shared Neighbours (Jaccard) 12.84
Average % Shared Neighbours (Otsuka) 15.74
Average % Shared Neighbours (Overlap Coefficient) 18.47
Average % Shared Cliques (k3-6) 52.15
Graphlets Similarity 0.687461
Paths Difference
Value adenosine_on_gp adenosine_off
Number Of Nodes in MetaPath 97 57
Specific Nodes in MetaPath 87 (89.69%) 47  (82.46%)
Shared Nodes in MetaPath 266 (29.42%) 266  (29.42%)
Number Of Links MetaPath 97 56
Specific Links in MetaPath 93 (95.88%) 52  (92.86%)
Shared Links in MetaPath 173 (16.24%) 173  (16.24%)
Number of Shortest Paths 891718 46028
Length Of Smallest Path 3 3
Average Path Length 27.1688 13.9177
Length of Longest Path 57 36
Minimum Path Strength 0.440417 0.395
Average Path Strength 5.45424 5.84784
Maximum Path Strength 21.67 21.9883
Minimum Path Correlation 0.705 0.700192
Average Path Correlation 0.970808 0.917185
Maximum Path Correlation 1 0.99
Minimum % Of Corr. Nodes 1.88679 3.125
Average % Of Corr. Nodes 43.064 45.3629
Maximum % Of Corr. Nodes 100 100
Minimum Path Hubs % 0 0
Average Path Hubs % 46.381 42.1282
Maximum Path Hubs % 100 100

Details about the values in these tables can be found in the corresponding documentation page .

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