Orange: nodes, hubs and links specific of alpha_on_gp network

Green: nodes, hubs and links shared by both networks

Purple: nodes, hubs and links specific of alpha_off network

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Owner: the name of the network the hub belong to or "Shared" if the corresponding hub is present in both networks.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub in the corresponding network.

Num Of Links: the number of links of the corresponding hub in the corresponding network.

ConSurf: this column reports the ConSurf conservation grades of each hub.


Index Hub Owner alpha_on_gp Avg Int. Strength alpha_off Avg Int. Strength alpha_on_gp Num Of Links alpha_off Num Of Links ConSurf
1G.HN.43 alpha_on_gp00408
2G.S1.04 alpha_on_gp500407
3G.S1.05 alpha_on_gp00409
4G.S1.06 alpha_on_gp41.66670408
5G.H1.04 alpha_on_gp00407
6G.S2.08 alpha_on_gp41.66670405
7G.S3.02 alpha_on_gp00403
8G.S3.03 alpha_on_gp91.66670407
9G.S3.04 alpha_on_gp91.66670506
10G.S3.05 alpha_on_gp500506
11G.S3.06 alpha_on_gp1000406
12G.H2.06 alpha_on_gp83.33330509
13G.H2.07 alpha_on_gp83.33330609
14G.h2s4.01 alpha_on_gp91.66670409
15G.S4.02 alpha_on_gp500407
16G.S4.04 alpha_on_gp83.33330409
17G.S4.06 alpha_on_gp500407
18G.s4h3.04 alpha_on_gp750608
19G.H3.01 alpha_on_gp00409
20G.H3.09 alpha_on_gp750509
21G.H3.17 alpha_on_gp500404
22G.H3.18 alpha_on_gp500409
23G.S5.02 alpha_on_gp83.33330406
24G.S5.04 alpha_on_gp83.33330409
25G.S5.05 alpha_on_gp83.33330509
26G.S5.07 alpha_on_gp00509
27G.s5hg.01 alpha_on_gp00409
28G.HG.04 alpha_on_gp58.33330408
29G.hgh4.02 alpha_on_gp500408
30G.H4.01 alpha_on_gp00403
31G.H4.03 alpha_on_gp16.66670403
32G.H4.15 alpha_on_gp750408
33G.h4s6.01 alpha_on_gp00404
34G.S6.01 alpha_on_gp500405
35G.S6.02 alpha_on_gp91.66670408
36G.H5.08 alpha_on_gp83.33330408
37G.H5.21 alpha_on_gp00404
38G.H5.25 alpha_on_gp500606
39b.1x16 alpha_on_gp00404
40b.1x19 alpha_on_gp00406
41b.h2x5 alpha_on_gp00405
42b.l1x3 alpha_on_gp1000609
43b.b2x1 alpha_on_gp83.33330508
44b.b2x5 alpha_on_gp1000407
45b.b3x3 alpha_on_gp33.33330408
46b.b3x4 alpha_on_gp00409
47b.b4x2 alpha_on_gp500408
48b.b4x4 alpha_on_gp500508
49b.b4x5 alpha_on_gp250407
50b.b4x6 alpha_on_gp1000809
51b.l4x2 alpha_on_gp750404
52b.b5x2 alpha_on_gp00507
53b.b5x3 alpha_on_gp1000509
54b.b5x5 alpha_on_gp00405
55b.b5x7 alpha_on_gp500407
56b.l5x1 alpha_on_gp91.66670508
57b.l5x5 alpha_on_gp1000809
58b.b6x5 alpha_on_gp1000406
59b.l6x5 alpha_on_gp83.33330404
60b.b7x1 alpha_on_gp33.33330404
61b.b8x4 alpha_on_gp1000606
62b.b9x3 alpha_on_gp500406
63b.l9x3 alpha_on_gp1000609
64b.l9x6 alpha_on_gp1000808
65b.b10x5 alpha_on_gp91.66670509
66b.l10x1 alpha_on_gp33.33330403
67b.b11x2 alpha_on_gp00407
68b.b11x3 alpha_on_gp00405
69b.b11x4 alpha_on_gp1000509
70b.l11x2 alpha_on_gp1000509
71b.b12x6 alpha_on_gp1000708
72b.b13x7 alpha_on_gp1000507
73b.l13x3 alpha_on_gp91.66670509
74b.l13x6 alpha_on_gp33.33330509
75b.b14x3 alpha_on_gp00405
76b.b15x1 alpha_on_gp83.33330509
77b.b15x2 alpha_on_gp250406
78b.b15x3 alpha_on_gp00409
79b.b16x4 alpha_on_gp91.66670406
80b.b16x5 alpha_on_gp250405
81b.b16x6 alpha_on_gp1000608
82b.b17x5 alpha_on_gp250407
83b.b17x7 alpha_on_gp91.66670408
84b.l17x3 alpha_on_gp750609
85b.b18x3 alpha_on_gp91.66670508
86b.b18x5 alpha_on_gp83.33330605
87b.l18x1 alpha_on_gp1000706
88b.b19x2 alpha_on_gp91.66670706
89b.b19x4 alpha_on_gp500408
90b.l19x1 alpha_on_gp500409
91b.l19x2 alpha_on_gp33.33330409
92b.b20x4 alpha_on_gp1000508
93b.b20x6 alpha_on_gp1000606
94b.b21x1 alpha_on_gp250407
95b.b21x7 alpha_on_gp1000705
96b.b22x5 alpha_on_gp91.66670407
97b.l22x5 alpha_on_gp41.66670509
98b.b23x6 alpha_on_gp1000507
99b.l23x1 alpha_on_gp00406
100b.l23x2 alpha_on_gp500408
101b.b24x4 alpha_on_gp33.33330406
102b.l25x3 alpha_on_gp1000609
103b.l25x6 alpha_on_gp500508
104b.b26x3 alpha_on_gp750406
105b.l26x3 alpha_on_gp500407
106b.l26x5 alpha_on_gp00405
107b.l27x1 alpha_on_gp1000609
108b.l27x2 alpha_on_gp83.33330409
109b.b28x4 alpha_on_gp500406
110b.b28x6 alpha_on_gp1000409
111g.h1x11 alpha_on_gp00509
112g.l1x4 alpha_on_gp250508
113g.h2x9 alpha_on_gp00404
114g.h2x11 alpha_on_gp33.33330406
115g.h2x15 alpha_on_gp00406
116g.ctx3 alpha_on_gp750509
117g.ctx6 alpha_on_gp250506
118g.ctx14 alpha_on_gp8.333330509
119g.ctx16 alpha_on_gp1000608
1201x31 alpha_on_gp00425
1211x43 alpha_on_gp00427
1221x50 alpha_on_gp91.66670529
123I1x50 alpha_on_gp91.66670429
1242x39 alpha_on_gp500439
1252x45 alpha_on_gp00439
1262x46 alpha_on_gp58.33330519
1272x50 alpha_on_gp500439
1283x35 alpha_on_gp83.33330537
1293x42 alpha_on_gp10050538
1303x43 alpha_on_gp750538
1313x50 alpha_on_gp2550439
1323x51 alpha_on_gp91.666750538
133I2x53 alpha_on_gp91.666750439
1344x50 alpha_on_gp83.33330439
1355x38 alpha_on_gp00425
1365x48 alpha_on_gp500629
1375x54 alpha_on_gp500528
1385x62 alpha_on_gp500419
1396x26 alpha_on_gp00405
1406x33 alpha_on_gp83.33330538
1416x49 alpha_on_gp16.66670427
1426x55 alpha_on_gp25100538
1437x37 alpha_on_gp500427
1447x49 alpha_on_gp83.33330539
1458x57 alpha_on_gp500438
1462x42 Shared91.666750668
147E1x50 Shared83.3333100778
1483x24 Shared050446
1493x28 Shared66.666750447
1503x49 Shared66.666750449
151I2x57 Shared91.666750567
152E2 Shared33.3333100587
1535x39 Shared5050545
1545x47 Shared91.666750658
1555x58 Shared91.666750668
1566x44 Shared83.3333100669
1576x48 Shared100100859
1586x51 Shared91.6667100568
1596x52 Shared41.6667100458
160E3 Shared8.3333350575
1617x42 Shared91.6667100658
1627x53 Shared91.666750649
1638x50 Shared91.6667100558
164Lig Shared10010012120
1652x57 alpha_off250348
1664x60 alpha_off050348
167I3 alpha_off050180
1687x38 alpha_off5050347
1698x49 alpha_off050348
1708x54 alpha_off16.66670348
171NT alpha_off050175
   
Orange: nodes, hubs and links specific of alpha_on_gp network

Green: nodes, hubs and links shared by both networks

Purple: nodes, hubs and links specific of alpha_off network

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Owner: the name of the network the link belong to or "Shared" if the corresponding link is present in both networks.

Recurrence: the relative Recurrence in the filtered pool of shortest paths.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.


Index Node1 Node2 Owner alpha_on_gp Recurrence alpha_off Recurrence alpha_on_gp Hub1? alpha_off Hub1? alpha_on_gp Hub2? alpha_off Hub2? ConSurf1 ConSurf2
1b.l26x5 g.ctx4 alpha_on_gp36.39230YesNoNoNo57
2g.ctx3 g.ctx4 alpha_on_gp36.7990YesNoNoNo97
3b.l22x3 g.ctx3 alpha_on_gp71.39220NoNoYesNo99
4b.l22x3 g.h2x15 alpha_on_gp71.76430NoNoYesNo96
5g.h2x11 g.h2x15 alpha_on_gp73.24870YesNoYesNo66
6b.l18x1 g.h2x11 alpha_on_gp73.23370YesNoYesNo66
7b.b22x5 b.l18x1 alpha_on_gp79.12510YesNoYesNo76
8b.b22x5 b.b23x2 alpha_on_gp80.94120YesNoNoNo76
9b.b21x7 b.b23x2 alpha_on_gp81.30330YesNoNoNo56
10b.b21x7 b.b24x6 alpha_on_gp86.19510YesNoNoNo58
11b.b23x6 b.b24x6 alpha_on_gp86.42470YesNoNoNo78
12b.b23x6 b.l23x2 alpha_on_gp89.51250YesNoYesNo78
13b.l21x7 b.l23x2 alpha_on_gp91.62380NoNoYesNo58
14b.l21x7 b.l23x1 alpha_on_gp91.97430NoNoYesNo56
15b.l23x1 b.l25x6 alpha_on_gp93.02360YesNoYesNo68
16b.l25x6 b.l27x1 alpha_on_gp93.44880YesNoYesNo89
17b.b2x1 b.l27x1 alpha_on_gp94.8340YesNoYesNo89
18G.H2.10 b.b2x1 alpha_on_gp48.76590NoNoYesNo68
19G.H2.10 b.l5x5 alpha_on_gp48.91390NoNoYesNo69
20G.h2s4.01 b.l5x5 alpha_on_gp1000YesNoYesNo99
21G.H2.07 G.h2s4.01 alpha_on_gp92.29710YesNoYesNo99
22G.H2.07 b.l9x6 alpha_on_gp84.7740YesNoYesNo98
23b.l11x1 b.l9x6 alpha_on_gp60.59530NoNoYesNo98
24b.b11x6 b.l11x1 alpha_on_gp60.67150NoNoNoNo99
25b.b11x6 b.l9x3 alpha_on_gp57.21010NoNoYesNo99
26b.b11x4 b.l9x3 alpha_on_gp48.9670YesNoYesNo99
27b.b10x3 b.b11x4 alpha_on_gp43.39170NoNoYesNo89
28b.b10x3 b.b6x2 alpha_on_gp43.16340NoNoNoNo88
29b.b10x2 b.b6x2 alpha_on_gp42.93460NoNoNoNo68
30b.b10x2 b.b10x4 alpha_on_gp42.70550NoNoNoNo66
31b.b10x4 b.b2x4 alpha_on_gp11.38750NoNoNoNo66
32b.b2x4 b.b6x5 alpha_on_gp11.1120NoNoYesNo66
33b.b3x3 b.b6x5 alpha_on_gp10.2780YesNoYesNo86
34b.b2x1 b.l3x1 alpha_on_gp48.76590YesNoNoNo89
35b.l3x1 b.l5x5 alpha_on_gp48.91390NoNoYesNo99
36G.H2.04 G.H2.07 alpha_on_gp93.22230NoNoYesNo99
37G.H2.04 G.H3.08 alpha_on_gp93.09460NoNoNoNo99
38G.H3.08 G.S4.04 alpha_on_gp92.78480NoNoYesNo99
39G.S4.04 G.s1h1.01 alpha_on_gp92.20710YesNoNoNo99
40G.H1.01 G.s1h1.01 alpha_on_gp92.09030NoNoNoNo99
41G.H1.01 G.S1.06 alpha_on_gp91.97320NoNoYesNo98
42G.S1.06 G.S3.05 alpha_on_gp88.15020YesNoYesNo86
43G.S1.04 G.S3.05 alpha_on_gp82.70810YesNoYesNo76
44G.S1.05 G.h2s4.01 alpha_on_gp15.24280YesNoYesNo99
45G.S1.05 G.S4.02 alpha_on_gp15.14910YesNoYesNo97
46G.H2.06 b.l9x6 alpha_on_gp34.59820YesNoYesNo98
47G.S4.02 G.S5.02 alpha_on_gp14.82010YesNoYesNo76
48G.S4.04 G.S4.06 alpha_on_gp12.97320YesNoYesNo97
49G.H3.09 G.h4s6.01 alpha_on_gp10.02920YesNoYesNo94
50G.H3.06 G.H4.14 alpha_on_gp13.78480NoNoNoNo76
513x53 G.H5.19 alpha_on_gp24.82050NoNoNoNo98
52G.H5.15 G.H5.19 alpha_on_gp78.98770NoNoNoNo88
53G.H5.11 G.H5.15 alpha_on_gp79.27970NoNoNoNo88
54G.H5.11 G.S1.04 alpha_on_gp79.42520NoNoYesNo87
553x54 G.H5.20 alpha_on_gp53.70340NoNoNoNo88
563x54 G.H5.19 alpha_on_gp54.22630NoNoNoNo88
57G.H5.20 G.H5.25 alpha_on_gp53.53810NoNoYesNo86
58G.H5.23 G.H5.25 alpha_on_gp10.69260NoNoYesNo46
593x50 G.H5.23 alpha_on_gp10.58210YesNoNoNo94
60b.b10x4 b.b14x3 alpha_on_gp32.97640NoNoYesNo65
61b.b14x3 b.b15x1 alpha_on_gp23.85890YesNoYesNo59
62b.b15x1 b.b16x6 alpha_on_gp21.8530YesNoYesNo98
63g.h1x11 g.h1x14 alpha_on_gp17.64880YesNoNoNo99
64b.1x11 g.h1x11 alpha_on_gp12.15030NoNoYesNo89
65G.H2.06 b.l19x1 alpha_on_gp33.57110YesNoYesNo99
66b.l17x5 b.l19x1 alpha_on_gp33.47010NoNoYesNo69
67b.l17x5 b.l19x2 alpha_on_gp33.2190NoNoYesNo69
68b.b19x6 b.l19x2 alpha_on_gp18.97010NoNoYesNo99
69b.b19x6 b.l17x3 alpha_on_gp18.70850NoNoYesNo99
70b.b20x6 b.l17x3 alpha_on_gp12.12530YesNoYesNo69
71b.b17x7 b.b20x6 alpha_on_gp11.04660YesNoYesNo86
72b.b20x2 b.l19x2 alpha_on_gp13.74660NoNoYesNo69
73b.b20x2 b.b20x4 alpha_on_gp12.95580NoNoYesNo68
74b.b20x4 b.b20x6 alpha_on_gp12.14360YesNoYesNo86
75g.ctx3 g.ctx6 alpha_on_gp11.30960YesNoYesNo96
76b.l22x1 g.ctx3 alpha_on_gp26.05710NoNoYesNo99
77b.b23x1 b.l22x1 alpha_on_gp25.64040NoNoNoNo59
78b.b23x1 b.b24x5 alpha_on_gp24.80580NoNoNoNo55
79b.b23x3 b.b24x5 alpha_on_gp23.96970NoNoNoNo75
80b.b23x3 b.b27x1 alpha_on_gp23.55110NoNoNoNo76
81b.b26x5 b.b27x1 alpha_on_gp23.1320NoNoNoNo76
82b.b22x4 b.b26x5 alpha_on_gp22.71260NoNoNoNo57
83b.b22x4 b.b26x3 alpha_on_gp22.29290NoNoYesNo56
84b.b26x3 b.b27x3 alpha_on_gp21.03120YesNoNoNo68
85b.b27x3 b.l25x3 alpha_on_gp16.34650NoNoYesNo89
86b.l25x3 b.l27x2 alpha_on_gp12.5420YesNoYesNo99
87b.l26x3 b.l26x5 alpha_on_gp18.29350YesNoYesNo75
88b.l26x1 b.l26x3 alpha_on_gp16.58350NoNoYesNo77
89b.b2x5 b.l26x1 alpha_on_gp16.17510YesNoNoNo77
90b.b2x5 b.b3x2 alpha_on_gp14.05110YesNoNoNo75
91b.b3x2 b.b4x6 alpha_on_gp13.63040NoNoYesNo59
92b.b19x2 b.b20x6 alpha_on_gp12.69960YesNoYesNo66
93b.b16x5 b.l14x6 alpha_on_gp13.27460YesNoNoNo53
94b.b16x7 b.l14x6 alpha_on_gp11.06310NoNoNoNo93
95b.l25x4 b.l27x2 alpha_on_gp10.85320NoNoYesNo59
968x56 b.l25x4 alpha_on_gp10.42250NoNoNoNo75
976x48 Lig alpha_on_gp33.14510YesYesYesYes90
985x54 6x44 alpha_on_gp37.25050YesNoYesYes89
995x54 5x58 alpha_on_gp38.51160YesNoYesYes88
1005x58 6x37 alpha_on_gp39.87470YesYesNoNo88
1016x37 G.H5.25 alpha_on_gp39.64980NoNoYesNo86
1021x50 2x50 alpha_on_gp11.09765.70969YesNoYesNo99
1032x50 7x49 alpha_on_gp14.51010YesNoYesNo99
1043x46 7x53 alpha_on_gp11.96980NoNoYesYes99
1052x42 3x46 alpha_on_gp12.28021.14232YesYesNoNo89
1063x49 I2x57 alpha_on_gp19.57690.480272YesYesYesYes97
1073x53 I2x57 alpha_on_gp24.6790.931843NoNoYesYes97
1083x50 7x53 alpha_on_gp10.40090YesNoYesYes99
109G.H3.09 G.S4.04 alpha_on_gp11.3990YesNoYesNo99
1107x42 Lig Shared13.163215.5275YesYesYesYes80
1116x44 6x48 Shared31.706692.9222YesYesYesYes99
1127x49 7x53 Shared17.610780.814YesNoYesYes99
1132x42 3x49 Shared20.033418.7115YesYesYesYes89
1143x28 E1x50 Shared11.456415.6844YesYesYesYes78
1152x63 E1x50 alpha_off1.09715.4606NoNoYesYes88
1162x63 Lig alpha_off016.4976NoNoYesYes80
1173x32 Lig alpha_off4.8324213.0324NoNoYesYes80
1182x50 3x39 alpha_off016.8459YesNoNoNo99
1193x39 6x44 alpha_off0100NoNoYesYes99
1205x47 6x44 alpha_off6.6643531.9027YesYesYesYes89
1215x47 6x52 alpha_off0.5798631.8836YesYesYesYes88
1226x52 Lig alpha_off0.50213560.8951YesYesYesYes80
1236x48 6x52 alpha_off0.30339730.0773YesYesYesYes98
1243x36 6x48 alpha_off0.25376129.7176NoNoYesYes79
1253x36 Lig alpha_off0.028281129.5855NoNoYesYes70
1266x48 6x51 alpha_off033.8774YesYesYesYes98
1276x51 Lig alpha_off3.0426329.708YesYesYesYes80
1288x50 8x54 alpha_off013.1013YesYesNoYes88
1297x53 8x50 alpha_off037.754YesYesYesYes98
1303x39 7x49 alpha_off087.8152NoNoYesNo99
1318x47 8x50 alpha_off1.3149817.3434NoNoYesYes98
1328x47 8x49 alpha_off0.87671511.7715NoNoNoYes98
1332x37 2x40 alpha_off042.1664NoNoNoNo89
1342x40 2x43 alpha_off043.1633NoNoNoNo98
1352x43 7x53 alpha_off044.1296NoNoYesYes89
1362x37 2x39 alpha_off0.30839941.1657NoNoYesNo89
1372x39 3x49 alpha_off0.24798922.2341YesNoYesYes99
1382x42 4x46 alpha_off6.7768912.3742YesYesNoNo88
1392x45 4x46 alpha_off6.5550711.2682YesNoNoNo98
1402x53 2x56 alpha_off021.3214NoNoNoNo88
1412x56 3x28 alpha_off8.6869311.7849NoNoYesYes87
1423x28 Lig alpha_off036.87YesYesYesYes70
1432x56 3x32 alpha_off4.5632711.9705NoNoNoNo88
1442x53 3x35 alpha_off2.3667718.6694NoNoYesNo87
1455x43 Lig alpha_off8.1064937.7215NoNoYesYes70
1465x39 5x43 alpha_off7.8377236.6059YesYesNoNo57
1475x39 E2 alpha_off4.6152127.9247YesYesYesYes57
1483x33 Lig alpha_off1.1570312.6363NoNoYesYes80
1493x33 4x57 alpha_off0.87844711.3103NoNoNoNo88
1503x43 6x44 alpha_off1.827530.6112YesNoYesYes89
1513x43 6x41 alpha_off027.4827YesNoNoNo87
1522x39 I2x57 alpha_off0.67624617.9193YesNoYesYes97
1535x58 6x41 alpha_off1.1910826.4131YesYesNoNo87
1543x47 5x58 alpha_off0.33360210.2101NoNoYesYes98
155I2x56 I2x57 alpha_off012.3742NoNoYesYes67
1564x41 I2x56 alpha_off0.30301210.1584NoNoNoNo86
1576x58 E2 alpha_off018.8818NoNoYesYes57
1586x58 E3 alpha_off0.31474815.363NoNoYesYes55
1592x50 7x46 alpha_off3.3233210.2101YesNoNoNo99

Here, those paths that begin and end at given residue pair(s) or that pass through a residue are used to generate a novel metapath. Such a path filtering is particularly recommended if some information on allosteric residues is available. The selection syntax for a residue pair ("Pairs") is C:C:c534,A:A:?600 (the lower-case "c" stands for cytosine and "?" indicates any non standard amino acid or nucleotide residue). Selection of more than one apical residue pair has the following syntax: C:C:c534,A:A:?600,C:C:c534,A:A:E41. Only one residue can be selected as a tail ("Tail"). For midway residue(s), each residue must be separated by a comma as well e.g. A:A:?600,A:A:E41.

Midway



Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.


2D representation of the interactions of this orthosteric/allosteric ligand.


Node1Node2OwnerNet1LinkStrengthNet2LinkStrengthComm1Comm2Node1ShellNode2Shell
2x63Ligalpha_off5.08500010
3x28Ligalpha_off5.7200010
3x32LigShared18.95512.16331210
3x33LigShared7.749.236670010
3x36LigShared6.248.838330210
5x43LigShared4.1652.935830010
6x51LigShared10.8411.16921210
6x52LigShared6.053.655831210
6x55LigShared6.6758.063331210
7x38LigShared16.3315.451210
7x42LigShared5.0157.48251210
2x563x28Shared4.385.808330221
2x563x32Shared4.387.394170221
2x577x39alpha_off4.05012722
2x577x42alpha_off10.05012721
2x593x28Shared4.0956.36250021
2x63E1x50Shared4.9553.201670012
3x28E1x50Shared9.073.940012
3x327x42Shared5.756.91211
3x334x57Shared4.852.69250012
3x366x48Shared5.2253.480830211
3x374x57alpha_off400212
3x375x461Shared7.9956.393330211
3x406x44Shared5.7152.826670222
5x395x43Shared6.9959.326672721
5x406x55Shared8.7758.64750021
5x475x48Shared7.945.8950222
5x476x44Shared3.6154.555830222
5x476x52Shared18.2220.71330221
6x446x48Shared8.164.343330221
6x486x51alpha_off4.5101211
6x486x52Shared4.517.1851211
6x487x41Shared9.156.096671212
6x516x52alpha_off8.0401211
6x516x55Shared8.0554.21251211
6x517x34Shared4.825.894171212
6x517x38Shared4.827.231671211
7x347x38alpha_off3.7501021
7x357x38alpha_off3.7200021
7x397x42Shared10.615.46751021
2x607x42Shared3.8155.616670021
6x447x45alpha_off5.6500222
5x446x52alpha_off3.4800221
E2x52Ligalpha_off3.3500010
3x374x56Shared2.283.80212
4x62E2x52alpha_off1.4900021
2x567x42alpha_on_gp04.128330221
2x603x28alpha_on_gp03.92250021
3x37Ligalpha_on_gp02.818330210
3x406x48alpha_on_gp08.9050221
6x55E2x52alpha_on_gp02.983331211
5x486x52alpha_on_gp03.124170221
6x487x45alpha_on_gp09.32251212
6x48Ligalpha_on_gp04.326671210
6x517x37alpha_on_gp02.681671212
7x387x42alpha_on_gp011.60331211
3x29E2x52alpha_on_gp02.550830721
5x461Ligalpha_on_gp04.166670210
5x476x48alpha_on_gp03.173330221
5x445x48alpha_on_gp03.4550222
5x446x55alpha_on_gp02.99250221
7x347x35alpha_on_gp03.16751022

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Difference Members
Id Description
alpha_on_gp alpha1_on_gp
alpha2_on_gp
alpha_off alpha1_off
alpha2_off
Network Difference
Value alpha_on_gp alpha_off
Imin 2.38167 3.53
Number of Linked Nodes 877 259
Number of Specific Nodes 627 (71.49%) 9  (3.47%)
Number of Shared Nodes 250 (28.51%) 250  (96.53%)
Number of Links 1042 278
Number of Specific Links 888 (85.22%) 124  (44.60%)
Number of Shared Links 154 (14.78%) 154  (55.40%)
Number of Hubs 164 26
Number of Specific Hubs 145 (88.41%) 7  (26.92%)
Number of Shared Hubs 19 (11.59%) 19  (73.08%)
Average % Shared Neighbours (Jaccard) 11.42
Average % Shared Neighbours (Otsuka) 14.42
Average % Shared Neighbours (Overlap Coefficient) 17.39
Average % Shared Cliques (k3-6) 51.24
Graphlets Similarity 0.639945
Paths Difference
Value alpha_on_gp alpha_off
Number Of Nodes in MetaPath 116 46
Specific Nodes in MetaPath 103 (88.79%) 33  (71.74%)
Shared Nodes in MetaPath 250 (28.51%) 250  (28.51%)
Number Of Links MetaPath 114 50
Specific Links in MetaPath 109 (95.61%) 45  (90.00%)
Shared Links in MetaPath 154 (14.78%) 154  (14.78%)
Number of Shortest Paths 1028257 84168
Length Of Smallest Path 3 3
Average Path Length 31.3116 13.8219
Length of Longest Path 71 28
Minimum Path Strength 0.268333 0.7625
Average Path Strength 5.28931 5.54152
Maximum Path Strength 19.3037 17.6425
Minimum Path Correlation 0.7 0.7
Average Path Correlation 0.972321 0.912763
Maximum Path Correlation 1 0.99
Minimum % Of Corr. Nodes 1.6129 4.54545
Average % Of Corr. Nodes 40.1957 40.7013
Maximum % Of Corr. Nodes 100 100
Minimum Path Hubs % 0 0
Average Path Hubs % 53.0931 42.5804
Maximum Path Hubs % 100 100

Details about the values in these tables can be found in the corresponding documentation page .

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