Orange: nodes, hubs and links specific of bb2_on_gp network

Green: nodes, hubs and links shared by both networks

Purple: nodes, hubs and links specific of bb2_off network

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Owner: the name of the network the hub belong to or "Shared" if the corresponding hub is present in both networks.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub in the corresponding network.

Num Of Links: the number of links of the corresponding hub in the corresponding network.

ConSurf: this column reports the ConSurf conservation grades of each hub.


Index Hub Owner bb2_on_gp Avg Int. Strength bb2_off Avg Int. Strength bb2_on_gp Num Of Links bb2_off Num Of Links ConSurf
12x46 bb2_on_gp5.4415.76529
22x53 bb2_on_gp3.948755.255427
32x56 bb2_on_gp5.5134.58517
42x59 bb2_on_gp4.271252.92416
52x60 bb2_on_gp5.5987.78526
6E1x52 bb2_on_gp7.343757.77333437
73x28 bb2_on_gp4.64.34425
83x29 bb2_on_gp7.006257.53333435
93x32 bb2_on_gp5.916.36436
103x37 bb2_on_gp3.541254.865426
11I2x50 bb2_on_gp2.6650408
12E2.H182 bb2_on_gp4.2122.81333531
13E2.F184 bb2_on_gp7.474172.485622
14E2.F193 bb2_on_gp5.608759.755421
155x35 bb2_on_gp7.756252.26411
165x44 bb2_on_gp6.046257.19667436
175x461 bb2_on_gp5.1464.39333536
185x60 bb2_on_gp3.296255.34333433
195x61 bb2_on_gp3.2246.19538
205x70 bb2_on_gp4.571250403
215x72 bb2_on_gp4.751250405
22I3.P245 bb2_on_gp4.4550503
236x23 bb2_on_gp3.8050403
246x30 bb2_on_gp6.098.635527
256x52 bb2_on_gp6.093756.95437
267x30 bb2_on_gp4.9996.63333534
277x31 bb2_on_gp6.2510.05514
287x38 bb2_on_gp6.857510.15615
297x49 bb2_on_gp7.4745.72667539
30G.HN.11 bb2_on_gp3.0370502
31G.H1.04 bb2_on_gp8.9080507
32G.h1ha.04 bb2_on_gp6.4750607
33H.HA.10 bb2_on_gp3.23250404
34H.HA.16 bb2_on_gp3.1050504
35H.hdhe.01 bb2_on_gp4.926250406
36H.HE.04 bb2_on_gp8.296250409
37H.HE.05 bb2_on_gp5.970406
38H.hehf.06 bb2_on_gp3.808750409
39H.HF.03 bb2_on_gp5.80509
40H.HF.06 bb2_on_gp12.3150406
41G.hfs2.01 bb2_on_gp3.2240505
42G.S2.01 bb2_on_gp4.9720509
43G.S3.01 bb2_on_gp3.44250404
44G.S3.03 bb2_on_gp7.1040507
45G.S3.08 bb2_on_gp4.7120509
46G.s3h2.03 bb2_on_gp6.1050409
47G.H2.04 bb2_on_gp6.6220509
48G.H2.06 bb2_on_gp6.912860709
49G.H2.07 bb2_on_gp7.970509
50G.h2s4.01 bb2_on_gp6.4010509
51G.h2s4.02 bb2_on_gp5.380407
52G.S4.02 bb2_on_gp5.13250407
53G.S4.03 bb2_on_gp3.6520507
54G.s4h3.01 bb2_on_gp5.3580507
55G.s4h3.04 bb2_on_gp5.232860708
56G.s4h3.05 bb2_on_gp6.2350609
57G.s4h3.08 bb2_on_gp6.20408
58G.H3.01 bb2_on_gp8.25250409
59G.H3.09 bb2_on_gp6.9980509
60G.H3.12 bb2_on_gp6.380507
61G.H3.15 bb2_on_gp5.5040508
62G.H3.17 bb2_on_gp5.6560505
63G.H3.18 bb2_on_gp6.320409
64G.S5.03 bb2_on_gp3.9520508
65G.S5.05 bb2_on_gp4.8080509
66G.S5.06 bb2_on_gp6.3250408
67G.S5.07 bb2_on_gp7.930509
68G.s5hg.01 bb2_on_gp4.9460509
69G.HG.07 bb2_on_gp7.085710709
70G.HG.08 bb2_on_gp2.810406
71G.HG.13 bb2_on_gp4.0450406
72G.HG.15 bb2_on_gp5.45250406
73G.hgh4.02 bb2_on_gp4.6980508
74G.hgh4.05 bb2_on_gp6.7850406
75G.H4.08 bb2_on_gp7.7350405
76G.H4.10 bb2_on_gp6.6540507
77G.H4.11 bb2_on_gp4.69750408
78G.H4.12 bb2_on_gp4.87750405
79G.H4.14 bb2_on_gp7.19750405
80G.S6.02 bb2_on_gp7.268570708
81G.S6.04 bb2_on_gp7.543750409
82G.S6.05 bb2_on_gp6.96750605
83G.s6h5.01 bb2_on_gp8.06750409
84G.s6h5.05 bb2_on_gp6.990409
85G.H5.03 bb2_on_gp7.546670608
86G.H5.13 bb2_on_gp7.278750407
87G.H5.19 bb2_on_gp3.803750408
88G.H5.20 bb2_on_gp3.560408
89G.H5.23 bb2_on_gp9.52250404
90G.H5.26 bb2_on_gp3.5010508
91b.lhb1x6 bb2_on_gp4.549170603
92b.lhb1x9 bb2_on_gp3.151250403
93b.lhb1x11 bb2_on_gp3.453750404
94b.b1x6 bb2_on_gp7.1420509
95b.l1x3 bb2_on_gp9.4620509
96b.b2x1 bb2_on_gp8.5360508
97b.b2x5 bb2_on_gp7.0560507
98b.b3x2 bb2_on_gp5.490405
99b.l3x2 bb2_on_gp4.980409
100b.b4x2 bb2_on_gp4.65750408
101b.b4x3 bb2_on_gp4.0880507
102b.b4x4 bb2_on_gp8.751250408
103b.b4x5 bb2_on_gp3.593750407
104b.b4x6 bb2_on_gp9.4950609
105b.l4x2 bb2_on_gp13.41120404
106b.b5x2 bb2_on_gp7.5850407
107b.b5x3 bb2_on_gp7.5570509
108b.b5x5 bb2_on_gp4.92250405
109b.b5x7 bb2_on_gp4.8660507
110b.l5x1 bb2_on_gp5.15750408
111b.l5x5 bb2_on_gp6.108330909
112b.b6x5 bb2_on_gp4.84750406
113b.b7x1 bb2_on_gp7.0020504
114b.b7x4 bb2_on_gp3.480408
115b.l7x2 bb2_on_gp4.59750409
116b.b8x3 bb2_on_gp3.91250406
117b.b8x4 bb2_on_gp4.9620506
118b.b9x4 bb2_on_gp5.350409
119b.l9x3 bb2_on_gp7.71250609
120b.l9x6 bb2_on_gp5.600710708
121b.b10x3 bb2_on_gp4.26250408
122b.b10x5 bb2_on_gp4.617140709
123b.l10x1 bb2_on_gp4.82250403
124b.b11x2 bb2_on_gp50407
125b.b11x4 bb2_on_gp5.3040509
126b.b11x5 bb2_on_gp4.420406
127b.l11x2 bb2_on_gp8.7240509
128b.b12x2 bb2_on_gp4.906250407
129b.b12x3 bb2_on_gp3.810408
130b.b12x6 bb2_on_gp10.3360508
131b.b13x7 bb2_on_gp9.0060507
132b.l13x3 bb2_on_gp7.285710709
133b.l13x6 bb2_on_gp5.3150509
134b.l13x7 bb2_on_gp3.91250409
135b.b14x3 bb2_on_gp5.540405
136b.b15x1 bb2_on_gp7.9540509
137b.b15x2 bb2_on_gp7.910406
138b.b15x3 bb2_on_gp4.60750409
139b.l15x1 bb2_on_gp4.340407
140b.l15x2 bb2_on_gp6.3660509
141b.b16x4 bb2_on_gp11.4950406
142b.b16x5 bb2_on_gp5.6780505
143b.b16x6 bb2_on_gp8.004290708
144b.b16x7 bb2_on_gp10.15750409
145b.b17x4 bb2_on_gp5.12750405
146b.b17x5 bb2_on_gp6.88250407
147b.b17x7 bb2_on_gp8.0450408
148b.l17x3 bb2_on_gp10.310609
149b.l17x6 bb2_on_gp9.681250409
150b.l17x7 bb2_on_gp5.1650407
151b.b18x3 bb2_on_gp5.86250408
152b.l18x1 bb2_on_gp7.200830606
153b.l18x2 bb2_on_gp7.0850407
154b.b19x2 bb2_on_gp7.5160506
155b.b19x4 bb2_on_gp5.4180508
156b.l19x2 bb2_on_gp8.2020509
157b.b20x2 bb2_on_gp6.410406
158b.b20x4 bb2_on_gp10.2750608
159b.b20x6 bb2_on_gp6.5050606
160b.b20x7 bb2_on_gp4.5650409
161b.l20x2 bb2_on_gp8.641250409
162b.b21x1 bb2_on_gp7.706250407
163b.b21x2 bb2_on_gp2.753750406
164b.b21x7 bb2_on_gp5.075710705
165b.l21x5 bb2_on_gp4.4980504
166b.b22x5 bb2_on_gp4.940507
167b.l22x5 bb2_on_gp7.850509
168b.b23x1 bb2_on_gp4.233750405
169b.b23x6 bb2_on_gp6.661430707
170b.l23x1 bb2_on_gp9.13750406
171b.b24x3 bb2_on_gp4.248750405
172b.b24x4 bb2_on_gp7.3340506
173b.b24x6 bb2_on_gp6.97250408
174b.l24x3 bb2_on_gp3.9450405
175b.b25x3 bb2_on_gp8.89750405
176b.l25x3 bb2_on_gp8.3160509
177b.l26x1 bb2_on_gp7.6950407
178b.l26x5 bb2_on_gp8.296670605
179b.b27x1 bb2_on_gp4.2740506
180b.b27x3 bb2_on_gp5.41750408
181b.l27x1 bb2_on_gp11.60140709
182b.l27x2 bb2_on_gp7.9550409
183b.b28x3 bb2_on_gp4.80407
184b.b28x4 bb2_on_gp7.13250406
185b.b28x6 bb2_on_gp8.158330609
186g.h1x10 bb2_on_gp4.59750409
187g.h1x11 bb2_on_gp1.201250409
188g.h2x11 bb2_on_gp9.001250406
189g.ctx3 bb2_on_gp6.5670509
190g.ctx6 bb2_on_gp3.906250406
191g.ctx14 bb2_on_gp5.960409
192g.ctx16 bb2_on_gp6.176670608
193H.hahb.06 bb2_on_gp3.9860500
194H.hahb.08 bb2_on_gp4.6420500
195H.HB.02 bb2_on_gp3.9320500
196H.HB.10 bb2_on_gp4.538750400
197H.HC.11 bb2_on_gp3.93750400
198H.hchd.01 bb2_on_gp3.2420500
199H.HD.07 bb2_on_gp5.14250400
200H.HE.11 bb2_on_gp4.1950400
201H.hehf.04 bb2_on_gp4.173750400
2021x39 Shared6.03210.1575547
2032x42 Shared4.1855.17167567
2042x50 Shared7.4258.0375549
2052x64 Shared6.709176.025644
206E1x50 Shared8.609175.95143678
2073x30 Shared4.283754.51446
2083x41 Shared4.3855.13445
2093x50 Shared4.5016.8475549
2103x51 Shared8.19758.59448
2114x61 Shared5.3698.8725545
212E2.E186 Shared6.52257.8125643
213E2.Y199 Shared11.1328.6625545
2145x58 Shared7.1877.794558
2156x48 Shared7.58257.634458
2166x55 Shared5.16311.34545
217E3.Y291 Shared9.9559.5575541
2187x42 Shared4.06757.37447
2197x45 Shared7.2356.7449
2208x50 Shared3.731257.98449
2218x54 Shared8.048758.9025447
222Lig Shared9.9481210.686932130
2231x43 bb2_off3.215.462357
2241x50 bb2_off5.816.7425249
2251x60 bb2_off4.823333.815346
2262x38 bb2_off3.203334.492357
2273x39 bb2_off4.4458.22249
2283x42 bb2_off4.6755.155248
2294x50 bb2_off8.488337.63349
230E2.L181 bb2_off3.174.9175144
2315x39 bb2_off6.425.39346
2325x47 bb2_off6.516677.226358
2336x51 bb2_off7.558334.6225345
2347x46 bb2_off7.445.975348
2357x54 bb2_off8.803337.1875347
   
Orange: nodes, hubs and links specific of bb2_on_gp network

Green: nodes, hubs and links shared by both networks

Purple: nodes, hubs and links specific of bb2_off network

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Owner: the name of the network the link belong to or "Shared" if the corresponding link is present in both networks.

Recurrence: the relative Recurrence in the filtered pool of shortest paths.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.


Index Node1 Node2 Owner bb2_on_gp Recurrence bb2_off Recurrence bb2_on_gp Hub1? bb2_off Hub1? bb2_on_gp Hub2? bb2_off Hub2? ConSurf1 ConSurf2
15x51 6x44 bb2_on_gp42.61360NoNoNoNo69
25x51 5x55 bb2_on_gp43.02720NoNoNoNo65
35x55 6x41 bb2_on_gp43.2340NoNoNoNo57
45x58 6x41 bb2_on_gp44.05980YesYesNoNo87
53x54 5x61 bb2_on_gp67.87040NoNoYesNo88
63x54 G.H5.20 bb2_on_gp68.28310NoNoYesNo88
73x50 5x58 bb2_on_gp20.59870YesYesYesYes98
8G.H5.17 G.H5.20 bb2_on_gp72.79650NoNoYesNo58
96x30 G.H5.17 bb2_on_gp73.00140YesNoNoNo75
106x30 G.H5.13 bb2_on_gp14.02850YesNoYesNo77
115x72 6x30 bb2_on_gp59.58740YesNoYesNo57
125x72 6x23 bb2_on_gp46.79150YesNoYesNo53
135x72 I3.P245 bb2_on_gp13.13350YesNoYesNo53
14G.H5.13 I3.P245 bb2_on_gp13.04910YesNoYesNo73
15G.H5.06 I3.P245 bb2_on_gp26.39550NoNoYesNo43
16G.H5.06 G.S6.04 bb2_on_gp25.90910NoNoYesNo49
17G.S6.04 I3.E247 bb2_on_gp25.12690YesNoNoNo94
18G.S6.05 I3.E247 bb2_on_gp25.09420YesNoNoNo54
196x23 6x26 bb2_on_gp48.12330YesNoNoNo33
206x25 6x26 bb2_on_gp49.0570NoNoNoNo43
216x25 G.h4s6.12 bb2_on_gp49.18310NoNoNoNo43
22G.S5.06 G.S6.05 bb2_on_gp24.85070YesNoYesNo85
23G.S5.04 G.S5.06 bb2_on_gp34.3210NoNoYesNo88
24G.H3.09 G.S5.04 bb2_on_gp34.34330YesNoNoNo98
25G.H3.09 G.S4.04 bb2_on_gp46.55460YesNoNoNo99
26G.H3.12 G.S4.04 bb2_on_gp46.45560YesNoNoNo79
27G.H2.04 G.H3.12 bb2_on_gp43.78620YesNoYesNo97
28G.H2.04 G.H2.07 bb2_on_gp55.80360YesNoYesNo99
29G.H2.02 G.H2.07 bb2_on_gp77.47210NoNoYesNo89
30G.H2.02 b.l9x6 bb2_on_gp38.77240NoNoYesNo88
31b.l11x1 b.l9x6 bb2_on_gp61.36710NoNoYesNo98
32b.b11x6 b.l11x1 bb2_on_gp1000NoNoNoNo99
33b.b11x6 b.l9x3 bb2_on_gp99.58480NoNoYesNo99
34b.b11x4 b.l9x3 bb2_on_gp67.23980YesNoYesNo99
35b.b11x4 b.b8x1 bb2_on_gp16.04460YesNoNoNo98
36b.b8x1 b.b9x4 bb2_on_gp15.99710NoNoYesNo89
37b.b8x3 b.b9x4 bb2_on_gp46.7080YesNoYesNo69
38b.b7x1 b.b8x3 bb2_on_gp46.55010YesNoYesNo46
39b.b7x1 b.l6x5 bb2_on_gp90.97450YesNoNoNo44
40b.l6x3 b.l6x5 bb2_on_gp90.33280NoNoNoNo64
41b.l6x3 b.l6x4 bb2_on_gp89.6910NoNoNoNo65
42b.b6x5 b.l6x4 bb2_on_gp89.37010YesNoNoNo65
43b.b6x5 b.l2x3 bb2_on_gp88.08630YesNoNoNo68
44b.b3x1 b.l2x3 bb2_on_gp87.76530NoNoNoNo58
45b.b3x1 b.b5x4 bb2_on_gp87.44430NoNoNoNo55
46b.b5x4 b.b5x5 bb2_on_gp87.12330NoNoYesNo55
47b.b4x5 b.b5x5 bb2_on_gp54.20840YesNoYesNo75
48b.b3x3 b.b4x5 bb2_on_gp21.93780NoNoYesNo87
49b.b3x3 b.b6x3 bb2_on_gp19.68120NoNoNoNo88
50b.b2x2 b.b6x3 bb2_on_gp19.03470NoNoNoNo78
51b.b26x2 b.b2x2 bb2_on_gp18.71180NoNoNoNo77
52b.b26x2 b.b2x3 bb2_on_gp18.3890NoNoNoNo76
53b.b27x2 b.b2x3 bb2_on_gp18.06640NoNoNoNo56
54b.b27x2 b.b2x5 bb2_on_gp17.74370NoNoYesNo57
55b.l4x1 g.ctx16 bb2_on_gp18.38180NoNoYesNo58
56b.l4x2 g.ctx16 bb2_on_gp27.40370YesNoYesNo48
57b.l2x5 b.l4x2 bb2_on_gp30.93720NoNoYesNo54
58b.b4x7 b.l2x5 bb2_on_gp28.99780NoNoNoNo85
59b.b4x7 b.l4x3 bb2_on_gp27.05840NoNoNoNo86
60b.b5x2 b.l4x3 bb2_on_gp25.1190YesNoNoNo76
61G.HN.37 b.b5x2 bb2_on_gp19.30060NoNoYesNo37
62G.HN.11 G.HN.37 bb2_on_gp15.42160YesNoNoNo23
63G.h4s6.10 G.h4s6.12 bb2_on_gp49.30950NoNoNoNo43
64G.h4s6.08 G.h4s6.10 bb2_on_gp49.56620NoNoNoNo74
65G.S6.01 G.h4s6.08 bb2_on_gp49.68140NoNoNoNo67
66G.H3.09 G.S6.01 bb2_on_gp11.40340YesNoNoNo96
67G.S5.02 G.S6.01 bb2_on_gp38.62720NoNoNoNo66
68G.S4.02 G.S5.02 bb2_on_gp39.33430YesNoNoNo76
69G.S1.05 G.S4.02 bb2_on_gp38.15980NoNoYesNo97
70G.S1.05 G.S3.08 bb2_on_gp16.29830NoNoYesNo99
71G.H2.07 G.S3.08 bb2_on_gp10.86770YesNoYesNo99
72G.S1.05 G.h2s4.01 bb2_on_gp21.94280NoNoYesNo99
73G.H2.07 G.h2s4.01 bb2_on_gp10.92720YesNoYesNo99
74b.l7x2 b.l9x6 bb2_on_gp22.7550YesNoYesNo98
75G.H2.02 b.l13x6 bb2_on_gp38.70670NoNoYesNo89
76b.l11x1 b.l13x6 bb2_on_gp38.67260NoNoYesNo99
77b.b11x4 b.b12x6 bb2_on_gp32.03720YesNoYesNo98
78b.b12x6 b.b9x4 bb2_on_gp31.98610YesNoYesNo89
79b.b12x4 b.l9x3 bb2_on_gp32.1880NoNoYesNo49
80b.b12x4 b.b12x6 bb2_on_gp32.03180NoNoYesNo48
81b.b10x3 b.b11x4 bb2_on_gp19.12660YesNoYesNo89
82b.b10x3 b.b11x2 bb2_on_gp16.12370YesNoYesNo87
83b.b10x5 b.b11x2 bb2_on_gp47.78660YesNoYesNo97
84b.b10x5 b.b7x1 bb2_on_gp46.66990YesNoYesNo94
85b.b11x2 b.b12x6 bb2_on_gp31.98790YesNoYesNo78
86b.b4x5 b.b5x7 bb2_on_gp31.30630YesNoYesNo77
87b.b5x7 b.b5x8 bb2_on_gp52.28810YesNoNoNo75
88b.b4x2 b.b5x8 bb2_on_gp51.64290YesNoNoNo85
89G.HN.47 b.b4x2 bb2_on_gp41.95320NoNoYesNo68
90G.HN.47 b.b4x4 bb2_on_gp35.49070NoNoYesNo68
91b.b4x4 b.b4x6 bb2_on_gp30.32340YesNoYesNo89
92b.b3x2 b.b4x6 bb2_on_gp13.55450YesNoYesNo59
93b.b3x2 b.l4x1 bb2_on_gp12.90320YesNoNoNo55
94b.b5x5 b.l8x8 bb2_on_gp32.27290YesNoNoNo54
95b.b5x7 b.l8x8 bb2_on_gp31.30570YesNoNoNo74
96b.b1x6 b.b4x6 bb2_on_gp15.48880YesNoYesNo99
97b.b1x6 b.b28x5 bb2_on_gp13.5540YesNoNoNo95
98b.b28x5 g.ctx16 bb2_on_gp12.26130NoNoYesNo58
99b.b2x5 b.l26x1 bb2_on_gp10.65320YesNoYesNo77
100G.s5hg.01 H.hdhe.05 bb2_on_gp12.51580YesNoNoNo98
101G.hfs2.02 H.hdhe.05 bb2_on_gp12.32730NoNoNoNo98
102G.hfs2.02 H.hdhe.04 bb2_on_gp12.23460NoNoNoNo97
103G.H3.17 b.l25x6 bb2_on_gp15.33890YesNoNoNo58
104b.l23x1 b.l25x6 bb2_on_gp21.01790YesNoNoNo68
105b.l21x7 b.l23x1 bb2_on_gp14.14160NoNoYesNo56
106b.b23x6 b.l21x7 bb2_on_gp13.32860YesNoNoNo75
1073x46 3x50 bb2_on_gp14.35570NoNoYesYes99
1086x48 Lig Shared34.385181.7407YesYesYesYes80
1096x44 6x48 Shared37.217886.0363NoNoYesYes98
1105x58 5x61 Shared65.659225.9452YesYesYesNo88
1113x32 Lig bb2_off0.83925710.8041YesNoYesYes60
112E2.Y199 Lig bb2_off022.4425YesYesYesYes50
1135x36 Lig bb2_off011.1828NoNoYesYes30
1146x52 Lig bb2_off0.016897919.3539YesNoYesYes70
1156x55 Lig bb2_off1.887811.9046YesYesYesYes50
1161x39 1x43 bb2_off028.5368YesYesNoYes77
1171x43 2x54 bb2_off045.305NoYesNoNo76
1182x54 7x46 bb2_off1.2681746.3168NoNoNoYes68
1193x39 7x46 bb2_off040.3408NoYesNoYes98
1203x39 6x44 bb2_off0100NoYesNoNo99
1211x43 7x42 bb2_off012.5969NoYesYesYes77
1221x42 7x42 bb2_off011.2597NoNoYesYes77
1231x50 2x50 bb2_off1.6734721.0283NoYesYesYes99
1242x50 3x39 bb2_off1.0422835.8026YesYesNoYes99
1251x50 2x47 bb2_off011.5437NoYesNoNo99
1268x50 8x54 bb2_off1.2748818.9279YesYesYesYes97
1277x53 8x50 bb2_off032.3649NoNoYesYes99
1286x40 7x53 bb2_off034.6015NoNoNoNo79
1296x40 7x49 bb2_off045.4233NoNoYesNo79
1302x50 7x49 bb2_off2.5043527.5132YesYesYesNo99
1317x45 7x49 bb2_off2.3625321.2118YesYesYesNo99
1323x39 7x45 bb2_off027.525NoYesYesYes99
1331x54 2x47 bb2_off0.41815610.1414NoNoNoNo79
1341x60 I1x50 bb2_off1.2597911.7981NoYesNoNo67
1352x40 I1x50 bb2_off1.679713.2714NoNoNoNo87
1362x37 2x40 bb2_off3.3591614.8985NoNoNoNo88
1372x37 2x39 bb2_off3.7789916.5138NoNoNoNo88
1382x39 3x49 bb2_off017.2061NoNoNoNo88
1392x38 3x49 bb2_off2.5186824.3418NoYesNoNo78
1402x38 2x42 bb2_off028.8267NoYesYesYes77
1412x42 3x42 bb2_off072.2738YesYesNoYes78
1423x42 4x49 bb2_off078.8533NoYesNoNo87
1433x41 4x49 bb2_off0.209979.6225YesYesNoNo57
1443x40 3x41 bb2_off0.20988586.6635NoNoYesYes85
1453x40 6x44 bb2_off088.5451NoNoNoNo89
1463x49 3x50 bb2_off010.1651NoNoYesYes89
1472x42 3x46 bb2_off9.8610840.2343YesYesNoNo79
1483x46 6x37 bb2_off039.187NoNoNoNo98
1493x50 6x37 bb2_off012.1117YesYesNoNo98
1501x39 2x57 bb2_off026.4422YesYesNoNo77
1512x57 2x58 bb2_off0.21007825.2174NoNoNoNo79
1522x58 E1x52 bb2_off023.969NoNoYesNo97
153E1x50 E1x52 bb2_off0.83975521.6082YesYesYesNo87
154E1x50 E2.L181 bb2_off012.5614YesYesNoYes84
1553x33 4x61 bb2_off013.8927NoNoYesYes45
1563x33 4x57 bb2_off012.3839NoNoNoNo47
1573x30 4x57 bb2_off1.2589110.8573YesYesNoNo67
1583x41 5x461 bb2_off010.7627YesYesYesNo56
1595x58 6x37 bb2_off0.002342835.4476YesYesNoNo88
1603x51 5x61 bb2_off1.891517.1765YesYesYesNo88
1613x50 3x53 bb2_off011.0585YesYesNoNo98
1626x58 E2.Y199 bb2_off011.6857NoNoYesYes45
163E2.Y199 E3.Y291 bb2_off0.001985810.4846YesYesYesYes51
164E3.S292 E3.Y291 bb2_off014.6678NoNoYesYes11
1655x47 6x52 bb2_off1.6793710.5142NoYesYesNo87
1666x54 6x58 bb2_off0.00014874910.3722NoNoNoNo54
1677x54 8x54 bb2_off0.63750111.9165NoYesYesYes77
1684x61 Lig bb2_off0.40838314.7565YesYesYesYes50

Here, those paths that begin and end at given residue pair(s) or that pass through a residue are used to generate a novel metapath. Such a path filtering is particularly recommended if some information on allosteric residues is available. The selection syntax for a residue pair ("Pairs") is C:C:c534,A:A:?600 (the lower-case "c" stands for cytosine and "?" indicates any non standard amino acid or nucleotide residue). Selection of more than one apical residue pair has the following syntax: C:C:c534,A:A:?600,C:C:c534,A:A:E41. Only one residue can be selected as a tail ("Tail"). For midway residue(s), each residue must be separated by a comma as well e.g. A:A:?600,A:A:E41.

Midway



Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.


2D representation of the interactions of this orthosteric/allosteric ligand.


Node1Node2OwnerNet1LinkStrengthNet2LinkStrengthComm1Comm2Node1ShellNode2Shell
3x29LigShared10.9715.2551110
3x32LigShared10.384.540110
4x61LigShared16.234.9251110
E2x52LigShared15.5417.9451110
E2.Y199Ligbb2_off13.0601110
5x36Ligbb2_off8.2300110
5x39Ligbb2_off7.1601110
6x48LigShared8.244.031110
6x51LigShared4.598.1651110
6x52LigShared6.445.091110
6x55LigShared26.115.651110
7x38LigShared10.1511.690110
1x352x64Shared9.673.0250021
1x362x64bb2_off9.7400021
1x391x43bb2_off10.8803122
1x392x60Shared12.645.1753121
1x397x42Shared14.444.133121
1x427x42bb2_off6.2800021
1x437x42bb2_off7.5403021
2x533x35Shared6.0130112
2x537x46Shared4.54.50112
2x5513x28bb2_off4.5600022
2x563x32Shared4.5810.680111
2x63E1x50Shared650111
E1.D104E2.E186bb2_off10.3900111
E1x49E2.F193bb2_off4.2800021
E1x50E1x52Shared15.0315.032112
3x25E1x50Shared3.925.222121
E1x50E2.L181bb2_off4.5602112
E1x50E2x50Shared6.5317.632111
3x25E2.L181Shared4.763.172122
3x25E2x50Shared7.287.282121
3x283x32Shared4.124.120121
3x294x61Shared6.293.1451111
3x294x65Shared5.346.2351111
3x334x57bb2_off4.7300112
3x334x61bb2_off9.2800111
3x366x48bb2_off4.900111
4x615x39Shared3.697.391111
4x65E2x52bb2_off5.3400111
E2.E186E2.S188Shared10.064.310112
E2.E186E2.T189Shared8.4711.9950112
E2.Q191E2.T189Shared5.673.5450112
E2.F193E2.Q191bb2_off15.2300111
E2.Y199E2x52Shared5.5613.911111
6x58E2.Y199bb2_off4.1200121
E2.Y199E3.Y291Shared11.9115.8851112
5x36E3.Y291bb2_off6.9500112
5x395x43Shared4.186.971112
5x396x55Shared6.534.91111
5x406x59Shared6.526.520122
5x436x55Shared7.633.181121
5x445x47Shared8.258.251122
5x446x52Shared6.799.6151121
5x476x52Shared7.625.441121
6x446x48Shared14.0313.030121
6x486x51bb2_off4.5201111
6x487x41bb2_off6.4801112
6x517x37bb2_off4.6901112
6x517x41Shared4.695.471112
6x547x33Shared4.563.040122
6x556x59Shared5.096.9951112
7x30E3.D295Shared8.823.150112
7x307x33bb2_off4.1100112
7x307x34Shared6.976.970112
7x317x35Shared10.057.540112
1x322x64bb2_off3.5200021
2x592x60bb2_off2.9200121
3x21E1x50Shared2.812.810021
3x24E1x50bb2_off2.8100021
1x392x57bb2_off2.6703122
E2.F184E2.S195Shared2.644.620111
6x546x58Shared2.516.260122
E2.E186E2.F184bb2_off2.3300111
E2.P200Ligbb2_off1.8300010
5x32E2.P200bb2_off1.6300021
E3.T296E3.V294bb2_off1.5900111
5x32E2.S202bb2_off1.4900022
1x311x32bb2_off1.4300022
7x397x42bb2_off1.2200021
2x642x65bb2_off1.1700112
1x351x36bb2_on_gp03.390022
1x351x39bb2_on_gp06.0450022
1x397x38bb2_on_gp03.093121
1x397x39bb2_on_gp011.723122
1x432x57bb2_on_gp03.253022
2x532x56bb2_on_gp04.760111
2x567x42bb2_on_gp04.890111
2x56Ligbb2_on_gp05.5450110
2x577x42bb2_on_gp04.160021
2x59E1x52bb2_on_gp06.5550122
2x593x28bb2_on_gp04.610122
2x593x32bb2_on_gp04.30121
2x602x63bb2_on_gp04.170111
2x602x64bb2_on_gp09.1950111
2x607x38bb2_on_gp04.760111
2x60Ligbb2_on_gp04.690110
2x63Ligbb2_on_gp015.2950110
2x647x31bb2_on_gp05.6750111
2x647x34bb2_on_gp03.180112
2x647x35bb2_on_gp04.230112
2x64Ligbb2_on_gp014.950110
E1.D104E1x49bb2_on_gp03.570112
E1.D104E2.F193bb2_on_gp04.180111
E1.D104Ligbb2_on_gp04.7050110
E1x50Ligbb2_on_gp05.9652110
3x28E1x52bb2_on_gp06.280122
3x283x29bb2_on_gp03.390121
3x335x461bb2_on_gp08.530112
3x33Ligbb2_on_gp05.040110
3x363x37bb2_on_gp03.680112
3x365x461bb2_on_gp04.5850112
3x36Ligbb2_on_gp05.510110
3x375x461bb2_on_gp03.7650122
4x614x65bb2_on_gp04.311111
4x61E2x52bb2_on_gp07.0751111
4x65Ligbb2_on_gp04.880110
E2.H182E2.P200bb2_on_gp06.10021
E2.H182E3.Y291bb2_on_gp03.270022
E2.F184E2.H201bb2_on_gp09.6150112
E2.F184E3.Y291bb2_on_gp07.7350112
E2.F184E3.V294bb2_on_gp03.930111
E2.F184Ligbb2_on_gp015.730110
E2.E186E3.T296bb2_on_gp05.6450111
E2.E186Ligbb2_on_gp011.8850110
E2.F193Ligbb2_on_gp010.3750110
E2.S195Ligbb2_on_gp012.7250110
E2x50Ligbb2_on_gp04.452110
5x35E2.Y199bb2_on_gp07.620121
5x36E2.Y199bb2_on_gp012.520111
6x59E2.Y199bb2_on_gp05.7250121
E2.P200E2.S202bb2_on_gp03.560012
E2.H201E3.Y291bb2_on_gp022.3250122
5x325x35bb2_on_gp06.380022
5x355x36bb2_on_gp04.580121
5x406x55bb2_on_gp05.090121
6x447x45bb2_on_gp06.040122
6x486x52bb2_on_gp04.231111
6x487x45bb2_on_gp09.041112
6x517x38bb2_on_gp09.041111
6x547x38bb2_on_gp05.6350121
6x57E3.D295bb2_on_gp05.1750122
6x577x30bb2_on_gp03.270121
6x587x30bb2_on_gp07.90121
6x587x38bb2_on_gp06.930121
E3.V294Ligbb2_on_gp08.510110
E3.T296Ligbb2_on_gp05.620110
7x30Ligbb2_on_gp03.7050110
7x31Ligbb2_on_gp015.5350110
7x42Ligbb2_on_gp03.093110
1x362x65bb2_on_gp04.1050022
2x53Ligbb2_on_gp03.5350110
E2.F184E2.F193bb2_on_gp03.2150111
E2.E186E2.F193bb2_on_gp04.6650111
E2.Q191Ligbb2_on_gp04.090110
1x322x65bb2_on_gp02.0750022
2x5512x56bb2_on_gp01.690021
3x24E1x52bb2_on_gp01.510022
1x317x31bb2_on_gp01.260021
7x287x31bb2_on_gp01.240021
E2.E186E2.E187bb2_on_gp00.6350112

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Difference Members
Id Description
bb2_on_gp 7W40-BB2-Bombesin-chim(NtGi1L-Gq)/β1/γ2
7W3Z-BB2-Gastrin Releasing Peptide-chim(NtGi1L-Gq)/β1/γ2
bb2_off 7W41-BB2-PD176252
Network Difference
Value bb2_on_gp bb2_off
Imin 2.845 3.63
Number of Linked Nodes 1012 267
Number of Specific Nodes 749 (74.01%) 4  (1.50%)
Number of Shared Nodes 263 (25.99%) 263  (98.50%)
Number of Links 1276 276
Number of Specific Links 1117 (87.54%) 117  (42.39%)
Number of Shared Links 159 (12.46%) 159  (57.61%)
Number of Hubs 222 34
Number of Specific Hubs 201 (90.54%) 13  (38.24%)
Number of Shared Hubs 21 (9.46%) 21  (61.76%)
Average % Shared Neighbours (Jaccard) 11.08
Average % Shared Neighbours (Otsuka) 13.73
Average % Shared Neighbours (Overlap Coefficient) 16.43
Average % Shared Cliques (k3-6) 50.55
Graphlets Similarity 0.603201
Paths Difference
Value bb2_on_gp bb2_off
Number Of Nodes in MetaPath 102 60
Specific Nodes in MetaPath 95 (93.14%) 53  (88.33%)
Shared Nodes in MetaPath 263 (25.99%) 263  (25.99%)
Number Of Links MetaPath 110 61
Specific Links in MetaPath 107 (97.27%) 58  (95.08%)
Shared Links in MetaPath 159 (12.46%) 159  (12.46%)
Number of Shortest Paths 15210158 33094
Length Of Smallest Path 3 3
Average Path Length 49.7795 13.0469
Length of Longest Path 74 31
Minimum Path Strength 1.0175 1.405
Average Path Strength 6.57843 6.87295
Maximum Path Strength 24.18 21.17
Minimum Path Correlation 0.7 0.7
Average Path Correlation 0.99713 0.926774
Maximum Path Correlation 1 0.99
Minimum % Of Corr. Nodes 1.63934 4.7619
Average % Of Corr. Nodes 34.1264 54.514
Maximum % Of Corr. Nodes 100 100
Minimum Path Hubs % 0 0
Average Path Hubs % 54.2263 42.5968
Maximum Path Hubs % 100 100

Details about the values in these tables can be found in the corresponding documentation page .

You can download a compressed (zip) file with structure(s), 3D outputs (as PyMol and VMD scripts) and numerical data files (as csv and plain text files).

Download bb2_off_on_gp.zip<



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