Orange: nodes, hubs and links specific of beta_on_gp network

Green: nodes, hubs and links shared by both networks

Purple: nodes, hubs and links specific of beta_off network

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Owner: the name of the network the hub belong to or "Shared" if the corresponding hub is present in both networks.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub in the corresponding network.

Num Of Links: the number of links of the corresponding hub in the corresponding network.

ConSurf: this column reports the ConSurf conservation grades of each hub.


Index Hub Owner beta_on_gp Avg Int. Strength beta_off Avg Int. Strength beta_on_gp Num Of Links beta_off Num Of Links ConSurf
1b.1x13 beta_on_gp00401
2b.lhb1x3 beta_on_gp16.66670402
3b.lhb1x6 beta_on_gp16.66670503
4b.l1x3 beta_on_gp1000509
5b.l1x6 beta_on_gp83.33330509
6b.b2x1 beta_on_gp61.11110508
7b.b2x5 beta_on_gp83.33330507
8b.b3x3 beta_on_gp500508
9b.l3x1 beta_on_gp55.55560409
10b.l3x2 beta_on_gp1000509
11b.b4x3 beta_on_gp55.55560507
12b.b4x6 beta_on_gp1000609
13b.l4x2 beta_on_gp500504
14b.b5x3 beta_on_gp1000709
15b.b5x5 beta_on_gp00405
16b.b5x7 beta_on_gp83.33330407
17b.l5x1 beta_on_gp83.33330508
18b.l5x5 beta_on_gp1000609
19b.b6x1 beta_on_gp22.22220409
20b.b6x5 beta_on_gp1000406
21b.l6x5 beta_on_gp33.33330404
22b.b7x1 beta_on_gp33.33330404
23b.b7x4 beta_on_gp55.55560408
24b.b8x3 beta_on_gp33.33330406
25b.b8x4 beta_on_gp88.88890506
26b.l9x3 beta_on_gp77.77780409
27b.l9x6 beta_on_gp1000908
28b.b10x5 beta_on_gp00509
29b.b11x4 beta_on_gp83.33330509
30b.l11x2 beta_on_gp1000409
31b.b12x6 beta_on_gp1000608
32b.l12x1 beta_on_gp00406
33b.b13x7 beta_on_gp88.88890507
34b.l13x3 beta_on_gp1000609
35b.l13x6 beta_on_gp500509
36b.b15x1 beta_on_gp500409
37b.b15x2 beta_on_gp33.33330406
38b.l15x2 beta_on_gp33.33330409
39b.b16x4 beta_on_gp83.33330406
40b.b16x5 beta_on_gp11.11110405
41b.b16x6 beta_on_gp1000608
42b.b17x5 beta_on_gp38.88890407
43b.b17x7 beta_on_gp55.55560408
44b.l17x3 beta_on_gp1000709
45b.l17x6 beta_on_gp55.55560409
46b.b18x3 beta_on_gp66.66670408
47b.b18x5 beta_on_gp500405
48b.l18x1 beta_on_gp1000806
49b.l18x2 beta_on_gp66.66670407
50b.b19x2 beta_on_gp1000506
51b.b19x4 beta_on_gp61.11110408
52b.l19x2 beta_on_gp500409
53b.b20x4 beta_on_gp1000508
54b.b20x6 beta_on_gp1000606
55b.b20x7 beta_on_gp00409
56b.l20x2 beta_on_gp22.22220409
57b.b21x1 beta_on_gp72.22220607
58b.b21x2 beta_on_gp16.66670406
59b.b21x3 beta_on_gp00406
60b.b21x7 beta_on_gp83.33330705
61b.l21x2 beta_on_gp16.66670404
62b.b22x5 beta_on_gp500407
63b.l22x5 beta_on_gp33.33330409
64b.b23x2 beta_on_gp00406
65b.b23x6 beta_on_gp1000607
66b.l23x1 beta_on_gp38.88890406
67b.b24x4 beta_on_gp83.33330406
68b.b24x6 beta_on_gp83.33330408
69b.l24x3 beta_on_gp22.22220405
70b.l25x3 beta_on_gp1000509
71b.l25x6 beta_on_gp83.33330508
72b.b26x3 beta_on_gp22.22220406
73b.l27x1 beta_on_gp1000709
74b.l27x2 beta_on_gp66.66670409
75b.b28x2 beta_on_gp00404
76b.b28x3 beta_on_gp33.33330407
77b.b28x4 beta_on_gp1000506
78b.b28x6 beta_on_gp1000409
79G.HN.34 beta_on_gp00404
80G.S1.06 beta_on_gp00408
81G.S2.06 beta_on_gp00409
82G.S3.03 beta_on_gp33.33330408
83G.S3.04 beta_on_gp500407
84G.S3.06 beta_on_gp83.33330406
85G.S3.07 beta_on_gp00409
86G.s3h2.03 beta_on_gp22.22220409
87G.H2.06 beta_on_gp1000509
88G.H2.07 beta_on_gp83.33330409
89G.h2s4.01 beta_on_gp66.66670409
90G.H3.08 beta_on_gp00409
91G.H3.09 beta_on_gp1000609
92G.H3.13 beta_on_gp83.33330506
93G.H3.17 beta_on_gp83.33330505
94G.S5.04 beta_on_gp44.44440409
95G.S5.05 beta_on_gp72.22220609
96G.HG.01 beta_on_gp38.88890406
97G.HG.03 beta_on_gp00407
98G.hgh4.02 beta_on_gp33.33330408
99G.hgh4.05 beta_on_gp22.22220506
100G.hgh4.21 beta_on_gp00404
101G.H4.08 beta_on_gp22.22220503
102G.H4.10 beta_on_gp83.33330406
103G.H4.12 beta_on_gp83.33330505
104G.H4.15 beta_on_gp38.88890408
105G.h4s6.20 beta_on_gp55.55560404
106G.S6.02 beta_on_gp83.33330508
107G.S6.05 beta_on_gp66.66670505
108G.s6h5.01 beta_on_gp55.55560409
109G.H5.03 beta_on_gp27.77780409
110G.H5.08 beta_on_gp83.33330409
111G.H5.13 beta_on_gp00408
112G.H5.16 beta_on_gp16.66670406
113G.H5.17 beta_on_gp72.22220506
114G.H5.20 beta_on_gp16.66670408
115G.H5.25 beta_on_gp33.33330409
116G.H5.26 beta_on_gp16.66670407
117g.h2x11 beta_on_gp83.33330406
118g.ctx3 beta_on_gp1000409
119g.ctx6 beta_on_gp00406
120g.ctx14 beta_on_gp500409
121g.ctx15 beta_on_gp44.44440409
122g.ctx16 beta_on_gp1000708
123g.ctx17 beta_on_gp00407
1241x39 beta_on_gp00436
1252x40 beta_on_gp38.88890539
1262x46 beta_on_gp72.22220419
1273x28 beta_on_gp66.66670536
1283x34 beta_on_gp00535
1293x51 beta_on_gp16.66670438
130I2x50 beta_on_gp00418
131I2x51 beta_on_gp61.11110426
1324x58 beta_on_gp16.66670525
1335x58 beta_on_gp10050639
1345x60 beta_on_gp16.66670435
135I3 beta_on_gp500733
1366x37 beta_on_gp00418
1376x49 beta_on_gp33.33330427
1386x55 beta_on_gp33.33330426
1397x49 beta_on_gp83.33330439
1407x52 beta_on_gp00438
141G.HN.30 beta_on_gp00400
142G.H1.01 beta_on_gp00400
143G.s4h3.04 beta_on_gp33.33330400
144G.hgh4.20 beta_on_gp11.11110400
1451x31 beta_on_gp00420
1461x60 Shared16.66670546
1472x42 Shared55.555678.5714658
1482x50 Shared88.88898.33333549
149E1x50 Shared100100777
150E1x52 Shared16.666785.7143445
1513x50 Shared5050449
1524x50 Shared00449
153E2 Shared10010013123
1545x47 Shared1000647
1555x50 Shared16.66670449
1566x44 Shared55.5556100459
1576x48 Shared10092.8571768
1586x51 Shared10092.8571657
1596x52 Shared10092.8571657
160E3 Shared10084.5238664
1617x39 Shared041.6667646
1627x42 Shared100100667
1637x53 Shared72.222291.6667559
1648x50 Shared100100668
165Lig Shared10010014120
1661x46 beta_off00347
1671x57 beta_off16.66670347
1682x41 beta_off00145
1692x59 beta_off00244
1703x27 beta_off00144
1713x41 beta_off033.3333346
1723x49 beta_off33.333361.9048349
1733x56 beta_off00246
174I2x53 beta_off22.222250367
175E2x52 beta_off11.111150244
1765x39 beta_off44.444441.6667347
1775x68 beta_off00347
1786x31 beta_off021.4286245
1796x41 beta_off00248
1806x59 beta_off00245
1817x33 beta_off00244
1828x54 beta_off00347
   
Orange: nodes, hubs and links specific of beta_on_gp network

Green: nodes, hubs and links shared by both networks

Purple: nodes, hubs and links specific of beta_off network

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Owner: the name of the network the link belong to or "Shared" if the corresponding link is present in both networks.

Recurrence: the relative Recurrence in the filtered pool of shortest paths.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.


Index Node1 Node2 Owner beta_on_gp Recurrence beta_off Recurrence beta_on_gp Hub1? beta_off Hub1? beta_on_gp Hub2? beta_off Hub2? ConSurf1 ConSurf2
1b.1x19 b.b21x1 beta_on_gp23.94690NoNoYesNo67
2b.1x19 b.b21x2 beta_on_gp25.37470NoNoYesNo66
3b.b21x2 g.h2x1 beta_on_gp26.46580YesNoNoNo68
4b.b21x4 g.h2x1 beta_on_gp26.82850NoNoNoNo58
5b.b20x7 b.b21x4 beta_on_gp27.19080YesNoNoNo95
6b.b20x7 b.l20x2 beta_on_gp28.27480YesNoYesNo99
7b.l18x5 b.l20x2 beta_on_gp32.56810NoNoYesNo29
8b.l18x3 b.l18x5 beta_on_gp32.92280NoNoNoNo52
9b.l18x1 b.l18x3 beta_on_gp33.19280YesNoNoNo65
10b.b22x5 b.l18x1 beta_on_gp31.1460YesNoYesNo76
11b.b22x5 b.b23x2 beta_on_gp33.2280YesNoYesNo76
12b.b21x7 b.b23x2 beta_on_gp34.30140YesNoYesNo56
13b.b21x7 b.b24x6 beta_on_gp42.48290YesNoYesNo58
14b.b23x6 b.b24x6 beta_on_gp42.84830YesNoYesNo78
15b.b23x6 b.l23x2 beta_on_gp47.1790YesNoNoNo78
16b.l21x7 b.l23x2 beta_on_gp48.61010NoNoNoNo58
17b.l21x7 b.l23x1 beta_on_gp49.310NoNoYesNo56
18b.l23x1 b.l25x6 beta_on_gp13.95660YesNoYesNo68
19b.l25x6 b.l27x1 beta_on_gp22.60290YesNoYesNo89
20b.b2x1 b.l27x1 beta_on_gp83.07560YesNoYesNo89
21b.b2x1 b.b6x1 beta_on_gp76.62150YesNoYesNo89
22b.b6x1 b.l9x6 beta_on_gp76.39880YesNoYesNo98
23b.b10x1 b.l9x6 beta_on_gp19.32470NoNoYesNo98
24b.b10x1 b.b11x5 beta_on_gp19.02110NoNoNoNo96
25b.b11x5 b.l13x7 beta_on_gp11.73710NoNoNoNo69
26b.l13x3 b.l13x7 beta_on_gp10.47110YesNoNoNo99
27G.H3.17 b.l23x1 beta_on_gp41.20440YesNoYesNo56
28G.H3.17 b.l27x1 beta_on_gp78.46860YesNoYesNo59
29b.b22x1 b.l23x1 beta_on_gp10.67130NoNoYesNo86
30b.b22x1 b.b22x2 beta_on_gp26.86760NoNoNoNo88
31b.b22x2 b.b26x3 beta_on_gp26.47480NoNoYesNo86
32b.b26x3 b.b27x3 beta_on_gp22.50210YesNoNoNo68
33b.b27x3 b.l25x3 beta_on_gp18.45480NoNoYesNo89
34b.l25x3 b.l27x2 beta_on_gp15.26090YesNoYesNo99
35b.b2x5 b.b3x2 beta_on_gp13.10520YesNoNoNo75
36b.b3x2 b.b4x6 beta_on_gp12.81960NoNoYesNo59
37b.b2x3 b.b2x5 beta_on_gp39.97370NoNoYesNo67
38b.b26x1 b.l27x1 beta_on_gp40.78610NoNoYesNo99
39b.b26x1 b.b26x2 beta_on_gp40.53690NoNoNoNo97
40b.b26x2 b.b2x3 beta_on_gp40.31590NoNoNoNo76
41b.l4x1 b.l4x2 beta_on_gp16.41320NoNoYesNo54
42b.l2x5 b.l4x2 beta_on_gp16.55690NoNoYesNo54
43b.l2x3 b.l2x5 beta_on_gp15.91440NoNoNoNo85
44b.b3x1 b.l2x3 beta_on_gp15.62650NoNoNoNo58
45b.b3x1 b.b6x5 beta_on_gp15.3380NoNoYesNo56
46b.b3x3 b.b6x5 beta_on_gp14.46980YesNoYesNo86
47b.b3x3 b.b4x3 beta_on_gp11.19350YesNoYesNo87
48b.l3x1 b.l5x5 beta_on_gp12.25720YesNoYesNo99
49b.l11x1 b.l9x6 beta_on_gp15.2990NoNoYesNo98
50b.b11x6 b.l11x1 beta_on_gp15.09150NoNoNoNo99
51b.b11x6 b.l9x3 beta_on_gp13.17460NoNoYesNo99
52b.b12x6 b.l9x3 beta_on_gp11.29620YesNoYesNo89
53G.H2.07 b.l9x6 beta_on_gp48.50970YesNoYesNo98
54b.b17x7 b.b21x1 beta_on_gp11.16990YesNoYesNo87
55b.l25x4 b.l27x2 beta_on_gp12.45640NoNoYesNo59
56I1x49 b.l25x4 beta_on_gp12.04610NoNoNoNo55
57G.H5.12 I2x51 beta_on_gp16.02540NoNoYesNo76
58G.H5.12 I2x50 beta_on_gp16.0550NoNoYesNo78
59G.H5.15 I2x50 beta_on_gp44.64520NoNoYesNo88
60G.H5.15 G.H5.19 beta_on_gp44.86780NoNoNoNo88
613x53 G.H5.19 beta_on_gp45.31180NoNoNoNo88
623x53 I2x53 beta_on_gp45.5331.67932NoNoNoYes87
632x42 3x46 beta_on_gp45.0162.12471YesYesNoNo89
643x46 3x50 beta_on_gp41.74130NoNoYesYes99
653x50 5x58 beta_on_gp55.22490YesYesYesNo99
665x58 6x37 beta_on_gp98.05160YesNoYesNo98
676x37 G.H5.25 beta_on_gp98.81120YesNoYesNo89
68G.H5.20 G.H5.25 beta_on_gp99.05970YesNoYesNo89
69G.H5.20 G.H5.26 beta_on_gp99.38430YesNoYesNo87
70G.H5.21 G.H5.26 beta_on_gp99.61190NoNoYesNo57
71G.H5.21 G.h4s6.12 beta_on_gp99.69050NoNoNoNo52
72G.h3s5.01 G.h4s6.12 beta_on_gp99.84620NoNoNoNo32
73G.H3.16 G.h3s5.01 beta_on_gp99.92330NoNoNoNo53
74G.H3.16 G.H3.17 beta_on_gp1000NoNoYesNo55
75G.S2.06 G.S3.03 beta_on_gp12.35580YesNoYesNo98
76G.H2.04 G.H2.07 beta_on_gp48.24420NoNoYesNo99
77G.H2.04 G.H3.08 beta_on_gp47.98020NoNoYesNo99
78G.H3.08 G.S4.04 beta_on_gp47.22390YesNoNoNo99
79G.H3.09 G.S4.04 beta_on_gp19.0040YesNoNoNo99
80G.S4.04 G.S5.04 beta_on_gp28.16310NoNoYesNo99
81G.H5.10 G.S6.02 beta_on_gp19.90910NoNoYesNo78
82G.H5.13 G.S6.02 beta_on_gp10.730YesNoYesNo88
835x68 G.H5.13 beta_on_gp11.76360NoYesYesNo78
845x68 G.H5.16 beta_on_gp24.04720NoYesYesNo76
85G.H5.16 I2x50 beta_on_gp26.33730YesNoYesNo68
86G.H5.17 G.S6.02 beta_on_gp10.69590YesNoYesNo68
875x68 G.H5.17 beta_on_gp12.03520NoYesYesNo76
88G.H3.09 G.H4.15 beta_on_gp15.65340YesNoYesNo98
89G.H4.15 G.S5.04 beta_on_gp15.56160YesNoYesNo89
90G.HG.15 G.s4h3.04 beta_on_gp14.80890NoNoYesNo70
91G.HG.15 G.hgh4.05 beta_on_gp15.4130NoNoYesNo76
92G.H4.10 G.hgh4.05 beta_on_gp20.74940YesNoYesNo66
93G.H4.10 G.H4.14 beta_on_gp24.5780YesNoNoNo66
94G.H3.06 G.H4.14 beta_on_gp25.71830NoNoNoNo66
95G.H3.06 G.H4.15 beta_on_gp29.26170NoNoYesNo68
965x47 6x44 beta_on_gp25.89930YesYesYesYes79
975x54 6x44 beta_on_gp32.72660NoNoYesYes89
985x54 5x58 beta_on_gp32.9190NoNoYesNo89
992x46 2x50 beta_on_gp11.09320YesNoYesYes99
1002x46 3x43 beta_on_gp10.94531.26679YesNoNoNo98
1013x43 7x53 beta_on_gp24.69010NoNoYesYes89
1023x50 7x53 beta_on_gp12.97010YesYesYesYes99
1033x43 7x49 beta_on_gp13.3620NoNoYesNo89
1046x40 7x53 beta_on_gp12.98551.13172NoNoYesYes89
1055x58 6x40 beta_on_gp13.15420YesNoNoNo98
1061x60 I1x49 beta_on_gp11.65660YesYesNoNo65
107b.b2x5 b.l4x1 beta_on_gp23.870YesNoNoNo75
108b.b22x1 b.l25x6 beta_on_gp16.58830NoNoYesNo88
1093x49 I2x53 Shared46.850551.6173NoYesNoYes97
1102x42 3x49 Shared47.285957.6884YesYesNoYes89
1116x52 Lig Shared16.713314.015YesYesYesYes70
1125x47 6x52 Shared19.641812.5913YesYesYesYes77
1132x50 7x46 Shared10.297781.2171YesYesNoNo99
1142x50 7x49 Shared11.499362.5365YesYesYesNo99
1151x50 2x50 Shared10.297720.0606NoNoYesYes99
1162x56 7x42 beta_off0.33151152.3255NoNoYesYes77
1172x53 2x56 beta_off0100NoNoNoNo87
1182x53 7x46 beta_off5.1546395.1519NoNoNoNo89
1191x46 7x46 beta_off4.1246116.7896NoYesNoNo79
1201x50 2x47 beta_off011.8283NoNoNoNo98
1211x54 2x47 beta_off0.84593410.1599NoNoNoNo78
1227x49 7x53 beta_off044.1881YesNoYesYes99
1237x53 8x50 beta_off041.5231YesYesYesYes98
1248x50 8x54 beta_off2.0811215.6104YesYesNoYes87
1251x52 8x54 beta_off1.2377810.6418NoNoNoYes67
1268x50 I1x50 beta_off6.6742413.0987YesYesNoNo88
1277x42 Lig beta_off6.9927456.2171YesYesYesYes70
1283x33 Lig beta_off3.8811274.5291NoNoYesYes60
1293x33 4x57 beta_off3.6615373.8354NoNoNoNo67
1303x34 4x57 beta_off2.5425373.1345YesNoNoNo57
1313x34 4x50 beta_off5.4125671.7107YesNoYesYes59
1322x45 4x50 beta_off6.3926669.5203NoNoYesYes99
1332x45 4x46 beta_off7.5438468.0235NoNoNoNo97
1342x42 4x46 beta_off7.7589362.6132YesYesNoNo87
1356x48 Lig beta_off015.9317YesYesYesYes80
1366x44 6x48 beta_off014.7379YesYesYesYes98
137E2x52 Lig beta_off5.0105362.8103NoYesYesYes40
138E2 E2x52 beta_off4.7052858.5864YesYesNoYes34
1394x61 E2 beta_off1.5470532.7979NoNoYesYes63
1403x30 4x61 beta_off1.3409531.8889NoNoNoNo66
1413x30 4x58 beta_off1.6002931.2354NoNoYesNo65
1423x27 4x58 beta_off0.50519430.1438NoYesYesNo45
1433x24 3x27 beta_off026.902NoNoNoYes44
1442x59 3x24 beta_off025.7995NoYesNoNo44
1452x59 E1x52 beta_off016.6253NoYesYesYes45
146E1x51 E1x52 beta_off0.31731414.6503NoNoYesYes45
1472x66 E1x51 beta_off012.2773NoNoNoNo44
1485x461 Lig beta_off0.13771612.0035NoNoYesYes60
1493x37 5x461 beta_off1.3823610.828NoNoNoNo66
150I2x52 I2x53 beta_off038.8654NoNoNoYes57
1515x68 I2x52 beta_off037.8103NoYesNoNo75
1523x54 5x68 beta_off030.1621NoNoNoYes97
1533x54 5x64 beta_off029.0997NoNoNoNo96
1543x55 5x64 beta_off026.8874NoNoNoNo76
1553x51 3x55 beta_off0.30524620.0752YesNoNoNo87
156E2 E3 beta_off020.1446YesYesYesYes34
1573x51 5x61 beta_off015.3877YesNoNoNo89
1585x58 5x61 beta_off014.1976YesNoNoNo99
1596x40 7x49 beta_off016.8991NoNoYesNo89
1606x40 7x52 beta_off016.4245NoNoYesNo88
1611x32 2x66 beta_off011.058NoNoNoNo04
1621x42 1x46 beta_off010.1599NoNoNoYes67
1632x56 3x32 beta_off0.31163548.8646NoNoNoNo77
1643x32 Lig beta_off0.6232749.3027NoNoYesYes70

Here, those paths that begin and end at given residue pair(s) or that pass through a residue are used to generate a novel metapath. Such a path filtering is particularly recommended if some information on allosteric residues is available. The selection syntax for a residue pair ("Pairs") is C:C:c534,A:A:?600 (the lower-case "c" stands for cytosine and "?" indicates any non standard amino acid or nucleotide residue). Selection of more than one apical residue pair has the following syntax: C:C:c534,A:A:?600,C:C:c534,A:A:E41. Only one residue can be selected as a tail ("Tail"). For midway residue(s), each residue must be separated by a comma as well e.g. A:A:?600,A:A:E41.

Midway



Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.


2D representation of the interactions of this orthosteric/allosteric ligand.


Node1Node2OwnerNet1LinkStrengthNet2LinkStrengthComm1Comm2Node1ShellNode2Shell
2x563x32Shared6.743817.221121
2x567x42Shared4.94.281121
2x577x42Shared3.683453.788330021
2x59E1x50Shared3.68443.406673122
2x593x28Shared6.37198.3153121
2x603x28Shared3.885713.438330021
3x28E1x50Shared11.02399.632223112
3x29E2x52beta_off6.99500021
3x327x42Shared10.04179.577221111
3x32LigShared18.763616.72941110
3x334x57Shared5.461074.306670012
3x33LigShared11.4789.303890010
3x366x48Shared8.479529.2651011
3x36LigShared5.302267.217781010
3x375x461Shared8.277989.145560021
3x406x44Shared6.716675.580560022
E2E2Shared114.86870.71331122
E2E2x52Shared14.7815.935561121
5x39E2Shared12.04967.117781122
E2E2x51Shared13.10839.197221122
5x39E2x52beta_off4.4711901121
E2x52LigShared9.0340516.91391110
5x395x43Shared14.04989.608891121
5x43LigShared6.967385.980560010
5x446x52Shared3.635.501670021
5x461LigShared3.66194.192780110
5x476x52Shared31.997119.58720121
6x446x48beta_off11.191900121
6x447x45beta_off6.9042900122
6x486x51Shared5.225245.290561111
6x486x52Shared5.082866.014441111
6x487x41Shared12.43510.71171112
6x48Ligbeta_off3.8354801110
6x516x52Shared7.707149.111111
6x517x34Shared8.488815.135561112
6x517x38Shared11.448715.30561111
6x51LigShared9.141317.7351110
6x52LigShared11.80455.659441110
6x557x34Shared4.938574.948330112
6x55LigShared8.271193.644440110
7x387x42Shared12.891311.62891111
7x38LigShared13.484414.82891110
7x397x42Shared13.82365.037780121
7x42LigShared5.014175.011671110
7x31E2x51beta_off2.9635700012
7x357x39beta_off2.400012
3x28Ligbeta_on_gp06.052783110
3x406x48beta_on_gp06.720021
5x446x55beta_on_gp04.138890021
5x4616x52beta_on_gp03.228330111
5x476x44beta_on_gp06.788330122
5x476x48beta_on_gp03.341670121
6x487x45beta_on_gp07.596111112
6x516x55beta_on_gp07.383331111
7x35Ligbeta_on_gp03.281110010
3x283x29beta_on_gp02.494443112
7x31Ligbeta_on_gp01.686110010

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Difference Members
Id Description
beta_on_gp beta1_on_gp
beta2_on_gp
beta3_on_gp
beta_off beta1_off
beta2_off
Network Difference
Value beta_on_gp beta_off
Imin 3.02278 3.57643
Number of Linked Nodes 900 272
Number of Specific Nodes 643 (71.44%) 15  (5.51%)
Number of Shared Nodes 257 (28.56%) 257  (94.49%)
Number of Links 1056 293
Number of Specific Links 887 (84.00%) 124  (42.32%)
Number of Shared Links 169 (16.00%) 169  (57.68%)
Number of Hubs 165 37
Number of Specific Hubs 145 (87.88%) 17  (45.95%)
Number of Shared Hubs 20 (12.12%) 20  (54.05%)
Average % Shared Neighbours (Jaccard) 13.37
Average % Shared Neighbours (Otsuka) 15.60
Average % Shared Neighbours (Overlap Coefficient) 17.85
Average % Shared Cliques (k3-6) 52.27
Graphlets Similarity 0.696953
Paths Difference
Value beta_on_gp beta_off
Number Of Nodes in MetaPath 112 56
Specific Nodes in MetaPath 97 (86.61%) 41  (73.21%)
Shared Nodes in MetaPath 257 (28.56%) 257  (28.56%)
Number Of Links MetaPath 115 56
Specific Links in MetaPath 108 (93.91%) 49  (87.50%)
Shared Links in MetaPath 169 (16.00%) 169  (16.00%)
Number of Shortest Paths 855956 49512
Length Of Smallest Path 3 3
Average Path Length 26.2072 15.6277
Length of Longest Path 57 39
Minimum Path Strength 0.280556 0.453125
Average Path Strength 5.92893 6.55711
Maximum Path Strength 22.5914 21.9008
Minimum Path Correlation 0.7 0.701905
Average Path Correlation 0.965913 0.913327
Maximum Path Correlation 1 0.989167
Minimum % Of Corr. Nodes 1.85185 2.94118
Average % Of Corr. Nodes 43.1131 42.2113
Maximum % Of Corr. Nodes 100 100
Minimum Path Hubs % 0 0
Average Path Hubs % 51.8233 38.9023
Maximum Path Hubs % 100 100

Details about the values in these tables can be found in the corresponding documentation page .

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