psnGPCR

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Orange: nodes, hubs and links specific of bombesin_off network

Green: nodes, hubs and links shared by both networks

Purple: nodes, hubs and links specific of bombesin_on network

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Owner: the name of the network the link belong to or "Shared" if the corresponding link is present in both networks.

Strength: the interaction strength between the two nodes or 0 if the link is not present.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Owner	bombesin_off Int. Strength	bombesin_on Int. Strength	bombesin_off Hub1?	bombesin_on Hub1?	bombesin_off Hub2?	bombesin_on Hub2?	ConSurf1	ConSurf2
1	1x31	1x34	bombesin_off	6.14	0	No	No	No	No	4	5
2	1x35	2x64	bombesin_off	9.67	0	No	No	Yes	Yes	6	4
3	1x36	2x64	bombesin_off	9.74	0	No	No	Yes	Yes	6	4
4	1x42	7x42	bombesin_off	6.28	0	No	No	Yes	Yes	7	7
5	1x43	2x54	bombesin_off	4.28	0	Yes	No	No	No	7	6
6	1x43	7x42	bombesin_off	7.54	0	Yes	No	Yes	Yes	7	7
7	1x50	2x47	bombesin_off	4.69	0	Yes	No	No	No	9	9
8	1x50	7x50	bombesin_off	11.4	0	Yes	No	No	No	9	9
9	1x51	2x51	bombesin_off	4.28	0	No	No	No	No	4	8
10	1x53	8x50	bombesin_off	7.31	0	No	No	Yes	Yes	9	9
11	1x54	2x44	bombesin_off	6.19	0	No	No	No	No	7	5
12	1x57	2x41	bombesin_off	4.87	0	No	Yes	No	No	7	6
13	2x40	I1x50	bombesin_off	4.21	0	No	No	No	No	8	7
14	2x38	2x42	bombesin_off	3.93	0	Yes	Yes	Yes	Yes	7	7
15	2x38	3x49	bombesin_off	8.76	0	Yes	Yes	No	No	7	8
16	2x39	3x49	bombesin_off	6.44	0	No	No	No	No	8	8
17	2x39	6x33	bombesin_off	6.57	0	No	No	No	No	8	8
18	2x42	3x42	bombesin_off	3.89	0	Yes	Yes	Yes	No	7	8
19	2x52	3x31	bombesin_off	4.28	0	No	No	No	No	7	5
20	2x53	7x46	bombesin_off	4.5	0	No	No	Yes	No	7	8
21	2x551	3x28	bombesin_off	4.56	0	No	No	No	Yes	5	5
22	2x58	E1x52	bombesin_off	4.33	0	No	No	No	Yes	9	7
23	2x62	E1x52	bombesin_off	3.96	0	No	No	No	Yes	4	7
24	E1x49	E2	bombesin_off	4.28	0	No	No	Yes	Yes	4	3
25	E1x50	E2	bombesin_off	4.56	0	Yes	Yes	Yes	Yes	8	3
26	3x26	E2	bombesin_off	9.68	0	No	No	Yes	Yes	7	3
27	3x29	4x61	bombesin_off	6.29	0	No	No	No	Yes	5	5
28	3x30	3x34	bombesin_off	3.89	0	Yes	No	No	No	6	5
29	3x30	4x54	bombesin_off	6.22	0	Yes	No	No	No	6	4
30	3x36	6x48	bombesin_off	4.9	0	No	No	Yes	No	7	8
31	3x37	3x41	bombesin_off	6.02	0	No	No	Yes	No	6	5
32	3x39	6x44	bombesin_off	7.44	0	Yes	No	No	Yes	9	9
33	3x39	7x45	bombesin_off	9.79	0	Yes	No	Yes	Yes	9	9
34	3x39	7x46	bombesin_off	4.59	0	Yes	No	Yes	No	9	8
35	3x40	6x44	bombesin_off	6.55	0	No	No	No	Yes	8	9
36	3x41	5x46	bombesin_off	4.29	0	Yes	No	No	No	5	6
37	3x42	4x49	bombesin_off	4.56	0	Yes	No	No	No	8	7
38	3x44	5x54	bombesin_off	6.08	0	No	No	No	No	7	8
39	3x46	6x37	bombesin_off	7.45	0	No	No	No	No	9	8
40	3x49	3x50	bombesin_off	5.96	0	No	No	Yes	No	8	9
41	3x50	3x53	bombesin_off	4.15	0	Yes	No	No	No	9	8
42	3x50	6x33	bombesin_off	13.36	0	Yes	No	No	No	9	8
43	3x50	6x37	bombesin_off	3.92	0	Yes	No	No	No	9	8
44	3x53	6x30	bombesin_off	4.53	0	No	No	No	Yes	8	7
45	3x56	I2x51	bombesin_off	6.2	0	No	No	No	No	6	5
46	I2x54	I2x57	bombesin_off	4.95	0	No	No	No	No	5	7
47	4x60	4x64	bombesin_off	4.33	0	No	No	No	No	7	5
48	4x65	E2x52	bombesin_off	5.34	0	No	No	No	No	5	4
49	6x58	E2	bombesin_off	4.12	0	No	Yes	Yes	Yes	4	3
50	5x32	E3	bombesin_off	18.27	0	No	No	Yes	Yes	1	3
51	5x33	5x37	bombesin_off	5.71	0	No	No	No	No	1	4
52	5x35	E3	bombesin_off	6.95	0	No	No	Yes	Yes	3	3
53	5x35	Lig	bombesin_off	8.23	0	No	No	Yes	Yes	3	0
54	5x38	6x55	bombesin_off	6.53	0	No	No	Yes	Yes	6	5
55	5x38	Lig	bombesin_off	7.16	0	No	No	Yes	Yes	6	0
56	5x39	6x56	bombesin_off	9.01	0	No	Yes	No	No	5	5
57	5x42	6x55	bombesin_off	7.63	0	No	No	Yes	Yes	6	5
58	5x43	5x48	bombesin_off	6.55	0	No	Yes	No	No	6	5
59	5x44	5x48	bombesin_off	4.47	0	No	No	No	No	4	5
60	5x47	5x51	bombesin_off	8.21	0	Yes	Yes	No	No	8	6
61	5x54	6x41	bombesin_off	6.14	0	No	No	No	No	8	7
62	5x58	5x61	bombesin_off	12.09	0	Yes	Yes	No	No	8	8
63	5x58	6x38	bombesin_off	14.07	0	Yes	Yes	No	No	8	5
64	5x65	6x31	bombesin_off	4.23	0	No	Yes	No	No	8	5
65	6x39	7x56	bombesin_off	5.96	0	No	No	No	No	6	7
66	6x40	7x53	bombesin_off	8.53	0	No	No	No	No	7	9
67	6x43	7x45	bombesin_off	4.12	0	No	No	Yes	Yes	7	9
68	6x47	7x40	bombesin_off	4.76	0	No	No	No	No	8	8
69	6x48	6x51	bombesin_off	4.52	0	Yes	No	Yes	No	8	5
70	6x48	7x41	bombesin_off	6.48	0	Yes	No	No	No	8	8
71	6x48	Lig	bombesin_off	8.24	0	Yes	No	Yes	Yes	8	0
72	6x51	7x37	bombesin_off	4.69	0	Yes	No	No	No	5	6
73	7x30	7x33	bombesin_off	4.11	0	No	Yes	No	No	4	4
74	8x54	8x58	bombesin_off	6.09	0	Yes	No	No	No	7	7
75	5x39	6x60	bombesin_off	3.82	0	No	Yes	No	No	5	5
76	3x51	5x61	bombesin_off	3.63	0	Yes	No	No	No	8	8
77	6x40	7x49	bombesin_off	3.62	0	No	No	No	Yes	7	9
78	1x32	2x64	bombesin_off	3.52	0	No	No	Yes	Yes	4	4
79	1x42	7x47	bombesin_off	3.27	0	No	No	No	No	7	7
80	5x68	6x27	bombesin_off	3.1	0	No	No	No	Yes	6	4
81	1x56	1x60	bombesin_off	3.07	0	No	No	Yes	No	7	6
82	5x68	6x31	bombesin_off	3.06	0	No	No	No	No	6	5
83	2x59	2x60	bombesin_off	2.92	0	No	Yes	No	Yes	6	6
84	6x26	6x29	bombesin_off	2.89	0	No	No	No	No	3	5
85	1x43	1x47	bombesin_off	2.85	0	Yes	No	No	No	7	6
86	4x52	4x55	bombesin_off	2.85	0	No	No	No	No	4	4
87	4x52	4x56	bombesin_off	2.85	0	No	No	No	No	4	6
88	5x40	5x44	bombesin_off	2.83	0	No	No	No	No	4	4
89	2x49	4x50	bombesin_off	2.81	0	No	No	Yes	No	8	9
90	3x24	E1x50	bombesin_off	2.81	0	No	No	Yes	Yes	6	8
91	5x63	5x64	bombesin_off	2.8	0	No	No	No	No	3	5
92	2x42	4x46	bombesin_off	2.77	0	Yes	Yes	No	No	7	7
93	6x25	6x28	bombesin_off	2.7	0	No	No	No	No	4	4
94	5x47	6x45	bombesin_off	2.67	0	Yes	Yes	No	No	8	6
95	5x58	6x34	bombesin_off	2.67	0	Yes	Yes	No	No	8	6
96	7x54	7x55	bombesin_off	2.34	0	Yes	No	No	No	7	6
97	6x42	6x45	bombesin_off	1.95	0	No	No	No	No	5	6
98	5x28	Lig	bombesin_off	1.83	0	No	No	Yes	Yes	5	0
99	1x40	1x43	bombesin_off	1.76	0	No	No	Yes	No	4	7
100	1x45	1x46	bombesin_off	1.76	0	No	No	No	No	6	8
101	7x47	7x48	bombesin_off	1.71	0	No	No	No	No	7	6
102	1x54	1x58	bombesin_off	1.64	0	No	No	No	No	7	3
103	5x28	5x31	bombesin_off	1.63	0	No	No	No	No	5	2
104	5x55	5x56	bombesin_off	1.62	0	No	No	No	No	5	4
105	3x26	4x62	bombesin_off	1.61	0	No	No	No	No	7	5
106	2x41	4x43	bombesin_off	1.59	0	No	No	No	No	6	1
107	7x43	7x48	bombesin_off	1.59	0	No	No	No	No	5	6
108	2x66	E1x51	bombesin_off	1.58	0	No	No	No	No	4	3
109	6x43	7x52	bombesin_off	1.58	0	No	No	No	No	7	8
110	5x30	5x31	bombesin_off	1.49	0	No	No	No	No	3	2
111	7x29	7x33	bombesin_off	1.47	0	No	No	No	No	2	4
112	3x52	4x45	bombesin_off	1.44	0	No	No	No	No	4	6
113	I2x54	I2x56	bombesin_off	1.44	0	No	No	No	No	5	5
114	1x31	1x32	bombesin_off	1.43	0	No	No	No	No	4	4
115	1x47	2x55	bombesin_off	1.43	0	No	No	No	No	6	5
116	6x35	7x56	bombesin_off	1.41	0	No	No	No	No	6	7
117	I2x53	I2x54	bombesin_off	1.37	0	No	No	No	No	6	5
118	6x32	8x49	bombesin_off	1.32	0	No	No	No	No	8	6
119	7x39	7x42	bombesin_off	1.22	0	No	No	Yes	Yes	5	7
120	2x64	2x65	bombesin_off	1.17	0	Yes	Yes	No	Yes	4	4
121	1x39	1x43	Shared	10.88	6.045	No	Yes	Yes	No	7	7
122	1x39	2x60	Shared	12.64	3.1625	No	Yes	No	Yes	7	6
123	1x39	7x42	Shared	14.44	6.19	No	Yes	Yes	Yes	7	7
124	1x44	1x48	Shared	7.14	3.59	No	No	No	No	5	5
125	1x45	7x51	Shared	5.02	3.22	No	No	No	No	6	5
126	1x49	7x50	Shared	4.06	2.03	No	No	No	No	8	9
127	1x50	2x50	Shared	5.39	6.06	Yes	No	Yes	Yes	9	9
128	1x50	2x51	Shared	5.49	3.4325	Yes	No	No	No	9	8
129	1x52	8x54	Shared	11.67	11.49	No	No	Yes	No	7	7
130	1x53	2x43	Shared	4.28	2.14	No	No	No	No	9	8
131	1x55	8x57	Shared	13.56	11.865	No	Yes	No	Yes	4	5
132	1x56	8x57	Shared	4.12	8.2325	No	No	No	Yes	7	5
133	1x57	I1x51	Shared	4.28	7.485	No	Yes	No	No	7	7
134	1x57	2x44	Shared	5.28	10.57	No	Yes	No	No	7	5
135	1x60	I1x50	Shared	6.09	6.29	Yes	No	No	No	6	7
136	2x37	2x39	Shared	8.15	8.37	No	No	No	No	8	8
137	2x37	2x40	Shared	13.62	8.555	No	No	No	No	8	8
138	2x38	4x42	Shared	5.09	3.23	Yes	Yes	No	No	7	7
139	2x42	3x45	Shared	6.93	4.16	Yes	Yes	No	No	7	7
140	2x42	3x46	Shared	7.31	2.44	Yes	Yes	No	No	7	9
141	2x42	4x45	Shared	6.2	7.135	Yes	Yes	No	No	7	6
142	2x45	3x42	Shared	4.8	8.32	No	No	Yes	No	9	8
143	2x45	4x50	Shared	4.94	8.2725	No	No	Yes	No	9	9
144	2x46	3x42	Shared	7.37	4.425	No	Yes	Yes	No	9	8
145	2x46	3x43	Shared	4.15	6.785	No	Yes	No	Yes	9	9
146	2x48	4x50	Shared	6.83	1.71	No	No	Yes	No	7	9
147	2x50	3x39	Shared	11.06	5.89	Yes	Yes	Yes	No	9	9
148	2x50	7x46	Shared	10.31	8.1	Yes	Yes	Yes	No	9	8
149	2x50	7x49	Shared	5.39	3.365	Yes	Yes	No	Yes	9	9
150	2x53	3x35	Shared	6.01	3.75	No	No	No	No	7	8
151	2x54	7x46	Shared	4.5	8.26	No	No	Yes	No	6	8
152	2x551	3x31	Shared	4.56	3.04	No	No	No	No	5	5
153	2x56	3x32	Shared	4.58	10.68	No	Yes	No	Yes	7	6
154	2x63	E1x50	Shared	6	8.5	No	Yes	Yes	Yes	5	8
155	E1	E2	Shared	12.78	8.06	No	No	Yes	Yes	4	3
156	E1x49	E1x51	Shared	7.29	2.7325	No	No	No	No	4	3
157	E1x50	E1x52	Shared	15.03	11.025	Yes	Yes	No	Yes	8	7
158	3x25	E1x50	Shared	3.92	3.265	No	No	Yes	Yes	9	8
159	E1x50	E2x50	Shared	6.53	11.425	Yes	Yes	No	No	8	9
160	3x22	E2	Shared	19.17	8.59	No	No	Yes	Yes	4	3
161	3x25	E2	Shared	4.76	3.295	No	No	Yes	Yes	9	3
162	3x25	E2x50	Shared	7.28	7.28	No	No	No	No	9	9
163	3x27	3x31	Shared	7.14	1.425	No	No	No	No	5	5
164	3x28	3x32	Shared	4.12	4.12	No	Yes	No	Yes	5	6
165	3x29	4x65	Shared	5.34	3.1175	No	No	No	No	5	5
166	3x29	Lig	Shared	10.97	16.0175	No	No	Yes	Yes	5	0
167	3x30	4x57	Shared	4.16	3.6225	Yes	No	No	No	6	7
168	3x32	Lig	Shared	10.38	4.31	No	Yes	Yes	Yes	6	0
169	3x33	4x57	Shared	4.73	3.155	No	No	No	No	4	7
170	3x33	4x61	Shared	9.28	3.645	No	No	No	Yes	4	5
171	3x34	4x54	Shared	7.53	6.8975	No	No	No	No	5	4
172	3x38	4x50	Shared	15.94	18.3875	No	No	Yes	No	7	9
173	3x40	3x41	Shared	3.93	3.935	No	No	Yes	No	8	5
174	3x40	5x50	Shared	5.3	4.415	No	No	No	No	8	9
175	3x41	4x49	Shared	6.28	5.655	Yes	No	No	No	5	7
176	3x47	5x54	Shared	10.84	6.965	No	No	No	No	9	8
177	3x47	5x58	Shared	5.09	11.7675	No	No	Yes	Yes	9	8
178	3x48	5x57	Shared	5.34	5.34	No	No	No	Yes	7	7
179	3x51	3x55	Shared	17.66	10.095	Yes	No	No	No	8	7
180	3x51	5x57	Shared	8.94	14.15	Yes	No	No	Yes	8	7
181	3x51	5x60	Shared	4.13	6.42	Yes	No	No	Yes	8	3
182	3x55	5x64	Shared	8.87	7.61	No	No	No	No	7	5
183	4x61	Lig	Shared	16.23	5.5375	No	Yes	Yes	Yes	5	0
184	E2	E2	Shared	74.67	38.0075	Yes	Yes	Yes	Yes	3	3
185	E2	E2x51	Shared	4.39	8.355	Yes	Yes	No	No	3	1
186	E2	E2x52	Shared	5.56	12.52	Yes	Yes	No	No	3	4
187	E2x52	Lig	Shared	15.54	20.4075	No	No	Yes	Yes	4	0
188	E2	E3	Shared	11.91	28.025	Yes	Yes	Yes	Yes	3	3
189	E2	Lig	Shared	13.06	37.2625	Yes	Yes	Yes	Yes	3	0
190	5x29	E3	Shared	9.76	11.1625	No	No	Yes	Yes	3	3
191	5x36	6x60	Shared	16.72	6.57	No	No	No	No	3	5
192	5x38	5x42	Shared	4.18	4.91	No	No	No	No	6	6
193	5x39	6x59	Shared	6.52	3.26	No	Yes	No	Yes	5	4
194	5x43	5x47	Shared	8.25	4.125	No	Yes	Yes	Yes	6	8
195	5x43	6x52	Shared	6.79	4.8075	No	Yes	No	Yes	6	7
196	5x45	5x46	Shared	5.24	2.295	No	No	No	No	5	6
197	5x47	6x49	Shared	9.38	5.61	Yes	Yes	No	No	8	6
198	5x47	6x52	Shared	7.62	12.335	Yes	Yes	No	Yes	8	7
199	5x58	6x37	Shared	5.05	5.995	Yes	Yes	No	No	8	8
200	5x59	5x60	Shared	9.28	3.67	No	No	No	Yes	3	3
201	6x26	6x30	Shared	12.74	1.75	No	No	No	Yes	3	7
202	6x36	6x40	Shared	3.89	3.805	No	No	No	No	8	7
203	6x36	7x56	Shared	10.32	8.73	No	No	No	No	8	7
204	6x44	6x48	Shared	14.03	15.535	No	Yes	Yes	No	9	8
205	6x46	7x40	Shared	6.09	10.05	No	No	No	No	6	8
206	6x47	7x45	Shared	4.72	3.145	No	No	Yes	Yes	8	9
207	6x51	7x41	Shared	4.69	7.205	Yes	No	No	No	5	8
208	6x51	Lig	Shared	4.59	7.8025	Yes	No	Yes	Yes	5	0
209	6x52	Lig	Shared	6.44	7.635	No	Yes	Yes	Yes	7	0
210	6x54	7x33	Shared	4.56	2.265	No	Yes	No	No	5	4
211	6x55	6x59	Shared	5.09	6.0425	Yes	Yes	No	Yes	5	4
212	6x55	Lig	Shared	26.11	7.465	Yes	Yes	Yes	Yes	5	0
213	6x57	6x61	Shared	28.31	7.915	No	No	No	No	4	2
214	6x61	E3	Shared	8.62	4.3175	No	No	Yes	Yes	2	3
215	E3	E3	Shared	7	17.495	Yes	Yes	Yes	Yes	3	3
216	7x27	E3	Shared	7.36	2.945	No	No	Yes	Yes	3	3
217	7x30	E3	Shared	8.82	4.725	No	Yes	Yes	Yes	4	3
218	7x30	7x34	Shared	6.97	6.225	No	Yes	No	Yes	4	4
219	7x31	7x35	Shared	10.05	7.305	No	Yes	No	No	4	4
220	7x38	Lig	Shared	10.15	5.8725	No	Yes	Yes	Yes	5	0
221	7x45	7x49	Shared	8.17	5.45	Yes	Yes	No	Yes	9	9
222	7x53	8x50	Shared	13.4	8.525	No	No	Yes	Yes	9	9
223	7x54	8x51	Shared	11.32	10.0325	Yes	No	No	No	7	8
224	7x54	8x54	Shared	9.28	9.0225	Yes	No	Yes	No	7	7
225	7x54	8x55	Shared	5.81	6.975	Yes	No	No	No	7	4
226	8x47	8x49	Shared	4.89	4.075	No	No	No	No	8	6
227	8x48	8x51	Shared	4.95	3.8375	No	No	No	No	4	8
228	8x50	8x54	Shared	8.57	3.215	Yes	Yes	Yes	No	9	7
229	3x30	4x59	Shared	3.77	2.1975	Yes	No	No	No	6	4
230	4x48	4x52	Shared	3.77	3.7675	No	No	No	No	3	4
231	2x57	2x58	Shared	3.74	2.7	No	No	No	No	7	9
232	3x37	4x53	Shared	3.71	2.785	No	No	No	No	6	8
233	4x56	5x46	Shared	3.65	3.62	No	No	No	No	6	6
234	5x53	5x57	Shared	3.63	3.63	No	No	No	Yes	7	7
235	1x48	1x49	Shared	3.53	2.62	No	No	No	No	5	8
236	4x59	4x60	Shared	3.39	3.46	No	No	No	No	4	7
237	5x49	5x50	Shared	3.39	3.39	No	No	No	No	5	9
238	6x49	6x50	Shared	3.28	3.395	No	No	No	No	6	9
239	1x54	2x47	Shared	3.25	1.2175	No	No	No	No	7	9
240	1x60	I1x49	Shared	3.23	3.96	Yes	No	No	No	6	6
241	2x38	4x39	Shared	2.98	2.235	Yes	Yes	No	No	7	2
242	1x60	8x53	Shared	2.87	5.26	Yes	No	No	No	6	6
243	3x54	5x65	Shared	2.85	2.85	No	No	No	Yes	8	8
244	4x51	4x55	Shared	2.85	1.8475	No	No	No	No	5	4
245	5x61	5x65	Shared	2.85	2.85	No	No	No	Yes	8	8
246	5x40	6x56	Shared	2.83	4.0675	No	No	No	No	4	5
247	3x21	E1x50	Shared	2.81	1.405	No	No	Yes	Yes	8	8
248	8x47	8x50	Shared	2.64	3.3	No	No	Yes	Yes	8	9
249	4x40	I2x57	Shared	2.63	1.97	No	No	No	No	3	7
250	5x56	5x60	Shared	2.62	1.6375	No	No	No	Yes	4	3
251	4x64	5x34	Shared	2.26	6.2225	No	No	No	Yes	5	1
252	1x46	7x47	Shared	1.96	1.96	No	No	No	No	8	7
253	3x23	3x24	Shared	1.76	1.36	No	No	No	No	2	6
254	2x38	4x38	Shared	1.7	1.7	Yes	Yes	No	No	7	7
255	5x48	5x52	Shared	1.62	0.81	No	No	No	No	5	3
256	1x38	1x42	Shared	1.54	1.1525	No	No	No	No	6	7
257	1x55	1x59	Shared	1.5	5.255	No	Yes	No	No	4	5
258	6x49	6x53	Shared	1.49	2.745	No	No	No	No	6	7
259	1x30	1x33	Shared	1.45	1.0875	No	No	No	No	3	3
260	I2x51	I2x52	Shared	1.39	4.16	No	No	No	No	5	5
261	I1x48	I1x51	Shared	1.24	3.955	No	No	No	No	5	7
262	1x35	1x36	bombesin_on	0	3.39	No	No	No	No	6	6
263	1x35	7x35	bombesin_on	0	4.6725	No	No	No	No	6	4
264	1x39	7x39	bombesin_on	0	7.12	No	Yes	No	No	7	5
265	1x43	2x57	bombesin_on	0	6.235	Yes	No	No	No	7	7
266	1x47	2x54	bombesin_on	0	3.8075	No	No	No	No	6	6
267	1x52	8x58	bombesin_on	0	3.685	No	No	No	No	7	7
268	1x53	2x47	bombesin_on	0	4.73	No	No	No	No	9	9
269	1x56	8x50	bombesin_on	0	4.395	No	No	Yes	Yes	7	9
270	1x59	8x57	bombesin_on	0	7.4425	No	No	No	Yes	5	5
271	8x53	I1x50	bombesin_on	0	7.925	No	No	No	No	6	7
272	2x38	2x39	bombesin_on	0	3.53	Yes	Yes	No	No	7	8
273	2x41	4x42	bombesin_on	0	4.2225	No	No	No	No	6	7
274	2x42	3x49	bombesin_on	0	6.5725	Yes	Yes	No	No	7	8
275	2x46	2x50	bombesin_on	0	5.0875	No	Yes	Yes	Yes	9	9
276	2x46	7x49	bombesin_on	0	6.18	No	Yes	No	Yes	9	9
277	2x51	2x55	bombesin_on	0	3.84	No	No	No	No	8	5
278	2x52	3x35	bombesin_on	0	6.76	No	No	No	No	7	8
279	2x53	2x56	bombesin_on	0	3.965	No	No	No	Yes	7	7
280	2x56	7x42	bombesin_on	0	3.84	No	Yes	Yes	Yes	7	7
281	2x56	Lig	bombesin_on	0	7.6375	No	Yes	Yes	Yes	7	0
282	2x57	7x42	bombesin_on	0	3.39	No	No	Yes	Yes	7	7
283	2x59	2x63	bombesin_on	0	3.9225	No	Yes	No	Yes	6	5
284	2x59	E1x52	bombesin_on	0	3.2775	No	Yes	No	Yes	6	7
285	2x59	3x28	bombesin_on	0	3.075	No	Yes	No	Yes	6	5
286	2x59	3x32	bombesin_on	0	5.015	No	Yes	No	Yes	6	6
287	2x60	2x64	bombesin_on	0	5.7475	No	Yes	Yes	Yes	6	4
288	2x60	7x38	bombesin_on	0	6.55	No	Yes	No	Yes	6	5
289	2x63	Lig	bombesin_on	0	17.485	No	Yes	Yes	Yes	5	0
290	2x64	7x31	bombesin_on	0	4.6325	Yes	Yes	No	Yes	4	4
291	2x64	7x34	bombesin_on	0	3.465	Yes	Yes	No	Yes	4	4
292	2x64	7x35	bombesin_on	0	4.46	Yes	Yes	No	No	4	4
293	2x64	Lig	bombesin_on	0	12.3	Yes	Yes	Yes	Yes	4	0
294	E1	Lig	bombesin_on	0	5.0525	No	No	Yes	Yes	4	0
295	3x28	E1x52	bombesin_on	0	6.91	No	Yes	No	Yes	5	7
296	3x22	3x26	bombesin_on	0	3.2925	No	No	No	No	4	7
297	3x28	3x29	bombesin_on	0	3.39	No	Yes	No	No	5	5
298	3x33	5x46	bombesin_on	0	4.265	No	No	No	No	4	6
299	3x34	4x53	bombesin_on	0	3.2	No	No	No	No	5	8
300	3x36	Lig	bombesin_on	0	5.585	No	No	Yes	Yes	7	0
301	3x38	4x53	bombesin_on	0	5.655	No	No	No	No	7	8
302	3x43	6x44	bombesin_on	0	3.56	No	Yes	No	Yes	9	9
303	3x43	7x45	bombesin_on	0	3.325	No	Yes	Yes	Yes	9	9
304	3x43	7x49	bombesin_on	0	4.805	No	Yes	No	Yes	9	9
305	3x47	5x57	bombesin_on	0	3.18	No	No	No	Yes	9	7
306	3x50	5x58	bombesin_on	0	4.63	Yes	No	Yes	Yes	9	8
307	3x54	5x61	bombesin_on	0	5.15	No	No	No	No	8	8
308	4x61	4x65	bombesin_on	0	3.59	No	Yes	No	No	5	5
309	4x61	E2x52	bombesin_on	0	5.8975	No	Yes	No	No	5	4
310	4x61	5x38	bombesin_on	0	3.695	No	Yes	No	No	5	6
311	4x65	Lig	bombesin_on	0	6.625	No	No	Yes	Yes	5	0
312	5x28	E2	bombesin_on	0	3.745	No	No	Yes	Yes	5	3
313	5x29	E2	bombesin_on	0	9.0575	No	No	Yes	Yes	3	3
314	E2x50	Lig	bombesin_on	0	5.175	No	No	Yes	Yes	9	0
315	5x34	E2	bombesin_on	0	3.81	No	Yes	Yes	Yes	1	3
316	5x35	E2	bombesin_on	0	8.44	No	No	Yes	Yes	3	3
317	6x55	E2	bombesin_on	0	4.7175	Yes	Yes	Yes	Yes	5	3
318	6x59	E2	bombesin_on	0	4.1325	No	Yes	Yes	Yes	4	3
319	5x31	5x34	bombesin_on	0	3.19	No	No	No	Yes	2	1
320	5x34	5x38	bombesin_on	0	3.335	No	Yes	No	No	1	6
321	5x39	6x55	bombesin_on	0	3.635	No	Yes	Yes	Yes	5	5
322	5x51	5x55	bombesin_on	0	3.375	No	No	No	No	6	5
323	5x51	6x44	bombesin_on	0	7.005	No	No	No	Yes	6	9
324	5x51	6x45	bombesin_on	0	5.145	No	No	No	No	6	6
325	5x55	6x41	bombesin_on	0	4.845	No	No	No	No	5	7
326	5x58	6x40	bombesin_on	0	4.125	Yes	Yes	No	No	8	7
327	5x58	6x41	bombesin_on	0	4.42	Yes	Yes	No	No	8	7
328	5x61	6x37	bombesin_on	0	3.84	No	No	No	No	8	8
329	5x62	6x38	bombesin_on	0	4.73	No	No	No	No	6	5
330	5x65	6x33	bombesin_on	0	4.15	No	Yes	No	No	8	8
331	5x68	6x30	bombesin_on	0	5.27	No	No	No	Yes	6	7
332	5x69	6x27	bombesin_on	0	3.225	No	No	No	Yes	3	4
333	5x70	6x31	bombesin_on	0	11.0875	No	No	No	No	0	5
334	6x23	I3	bombesin_on	0	7.345	No	No	No	No	0	0
335	6x22	I3	bombesin_on	0	6.895	No	No	No	No	0	0
336	6x23	6x27	bombesin_on	0	5.3	No	No	No	Yes	0	4
337	6x40	7x52	bombesin_on	0	3.465	No	No	No	No	7	8
338	6x48	6x52	bombesin_on	0	6.345	Yes	No	No	Yes	8	7
339	6x48	7x45	bombesin_on	0	12.995	Yes	No	Yes	Yes	8	9
340	6x50	7x40	bombesin_on	0	4.105	No	No	No	No	9	8
341	6x51	7x38	bombesin_on	0	4.52	Yes	No	No	Yes	5	5
342	6x54	6x58	bombesin_on	0	6.165	No	Yes	No	Yes	5	4
343	6x54	7x34	bombesin_on	0	4.1125	No	Yes	No	Yes	5	4
344	6x54	7x38	bombesin_on	0	3.4225	No	Yes	No	Yes	5	5
345	6x57	E3	bombesin_on	0	4.3125	No	No	Yes	Yes	4	3
346	6x58	7x30	bombesin_on	0	7.9	No	Yes	No	Yes	4	4
347	6x58	7x34	bombesin_on	0	3.905	No	Yes	No	Yes	4	4
348	6x58	7x38	bombesin_on	0	5.065	No	Yes	No	Yes	4	5
349	E3	Lig	bombesin_on	0	8.6975	Yes	Yes	Yes	Yes	3	0
350	7x30	Lig	bombesin_on	0	7.3425	No	Yes	Yes	Yes	4	0
351	7x31	Lig	bombesin_on	0	15.3275	No	Yes	Yes	Yes	4	0
352	7x42	Lig	bombesin_on	0	3.41	Yes	Yes	Yes	Yes	7	0
353	7x49	7x50	bombesin_on	0	3.26	No	Yes	No	No	9	9
354	Lig	Lig	bombesin_on	0	24.355	Yes	Yes	Yes	Yes	0	0
355	2x53	Lig	bombesin_on	0	3.1825	No	No	Yes	Yes	7	0
356	2x60	7x42	bombesin_on	0	3.8825	No	Yes	Yes	Yes	6	7
357	8x50	I1x50	bombesin_on	0	3.11	Yes	Yes	No	No	9	7
358	4x61	5x39	bombesin_on	0	3.695	No	Yes	No	Yes	5	5
359	4x64	5x35	bombesin_on	0	12.445	No	No	No	No	5	3
360	5x36	E2	bombesin_on	0	8.345	No	No	Yes	Yes	3	3
361	5x39	E2	bombesin_on	0	5.445	No	Yes	Yes	Yes	5	3
362	5x33	E3	bombesin_on	0	8.24	No	No	Yes	Yes	1	3
363	5x36	E3	bombesin_on	0	4.87	No	No	Yes	Yes	3	3
364	5x37	6x60	bombesin_on	0	3.1	No	No	No	No	4	5
365	5x39	5x43	bombesin_on	0	5.965	No	Yes	No	Yes	5	6
366	5x40	6x59	bombesin_on	0	3.26	No	No	No	Yes	4	4
367	5x43	5x461	bombesin_on	0	3.625	No	Yes	No	No	6	0
368	5x44	5x47	bombesin_on	0	5.895	No	No	Yes	Yes	4	8
369	5x44	6x56	bombesin_on	0	6.22	No	No	No	No	4	5
370	5x54	6x44	bombesin_on	0	4.395	No	No	No	Yes	8	9
371	5x65	6x30	bombesin_on	0	3.645	No	Yes	No	Yes	8	7
372	5x66	6x31	bombesin_on	0	4.36	No	No	No	No	4	5
373	6x22	6x23	bombesin_on	0	3.425	No	No	No	No	0	0
374	6x27	6x30	bombesin_on	0	3.1	No	Yes	No	Yes	4	7
375	3x44	5x53	bombesin_on	0	3.04	No	No	No	No	7	7
376	3x55	3x56	bombesin_on	0	2.87	No	No	No	No	7	6
377	2x41	2x42	bombesin_on	0	2.815	No	No	Yes	Yes	6	7
378	6x50	7x37	bombesin_on	0	2.805	No	No	No	No	9	6
379	1x29	1x33	bombesin_on	0	2.7825	No	No	No	No	0	3
380	4x39	4x43	bombesin_on	0	2.775	No	No	No	No	2	1
381	5x65	6x34	bombesin_on	0	2.76	No	Yes	No	No	8	6
382	6x25	6x26	bombesin_on	0	2.71	No	No	No	No	4	3
383	5x70	5x71	bombesin_on	0	2.675	No	No	No	No	0	0
384	1x28	7x28	bombesin_on	0	2.65	No	No	No	No	0	3
385	5x30	E3	bombesin_on	0	2.64	No	No	Yes	Yes	3	3
386	4x63	4x64	bombesin_on	0	2.62	No	No	No	No	4	5
387	3x41	4x52	bombesin_on	0	2.62	Yes	No	No	No	5	4
388	3x30	4x62	bombesin_on	0	2.5825	Yes	No	No	No	6	5
389	5x49	5x53	bombesin_on	0	2.5725	No	No	No	No	5	7
390	1x45	7x47	bombesin_on	0	2.56	No	No	No	No	6	7
391	2x551	2x56	bombesin_on	0	2.535	No	No	No	Yes	5	7
392	1x57	2x43	bombesin_on	0	2.51	No	Yes	No	No	7	8
393	2x43	3x46	bombesin_on	0	2.4975	No	No	No	No	8	9
394	5x72	5x73	bombesin_on	0	2.465	No	No	No	No	0	0
395	1x53	7x50	bombesin_on	0	2.46	No	No	No	No	9	9
396	E1	E1x49	bombesin_on	0	2.435	No	No	No	No	4	4
397	6x32	7x56	bombesin_on	0	2.43	No	No	No	No	8	7
398	5x72	6x30	bombesin_on	0	2.4275	No	No	No	Yes	0	7
399	1x58	1x59	bombesin_on	0	2.365	No	No	No	No	3	5
400	6x39	6x43	bombesin_on	0	2.345	No	No	No	No	6	7
401	1x34	1x38	bombesin_on	0	2.29	No	No	No	No	5	6
402	1x41	1x45	bombesin_on	0	2.26	No	No	No	No	4	6
403	1x49	7x51	bombesin_on	0	2.26	No	No	No	No	8	5
404	3x24	E1x52	bombesin_on	0	2.26	No	No	No	Yes	6	7
405	8x52	8x53	bombesin_on	0	2.255	No	No	No	No	4	6
406	6x43	7x48	bombesin_on	0	2.235	No	No	No	No	7	6
407	6x27	6x31	bombesin_on	0	2.18	No	Yes	No	No	4	5
408	1x57	8x50	bombesin_on	0	2.145	No	Yes	Yes	Yes	7	9
409	5x45	5x48	bombesin_on	0	2.075	No	No	No	No	5	5
410	7x55	7x56	bombesin_on	0	2.075	No	No	No	No	6	7
411	2x45	4x46	bombesin_on	0	2.0625	No	No	No	No	9	7
412	1x36	2x65	bombesin_on	0	2.0525	No	No	No	Yes	6	4
413	6x24	I3	bombesin_on	0	2.025	No	No	No	No	0	0
414	1x33	1x37	bombesin_on	0	2.0025	No	No	No	No	3	6
415	1x39	1x40	bombesin_on	0	1.895	No	Yes	No	No	7	4
416	1x29	1x32	bombesin_on	0	1.82	No	No	No	No	0	4
417	5x62	6x34	bombesin_on	0	1.79	No	No	No	No	6	6
418	I2x56	I2x57	bombesin_on	0	1.7425	No	No	No	No	5	7
419	7x27	7x29	bombesin_on	0	1.68	No	No	No	No	3	2
420	3x56	I2x50	bombesin_on	0	1.535	No	No	No	No	6	8
421	7x45	7x48	bombesin_on	0	1.48	Yes	Yes	No	No	9	6
422	5x67	5x70	bombesin_on	0	1.41	No	No	No	No	4	0
423	2x61	2x65	bombesin_on	0	1.385	No	No	No	Yes	6	4
424	5x32	5x35	bombesin_on	0	1.26	No	No	No	No	1	3
425	1x38	7x39	bombesin_on	0	1.1175	No	No	No	No	6	5
426	2x65	2x66	bombesin_on	0	1.07	No	Yes	No	No	4	4
427	4x40	4x44	bombesin_on	0	1.06	No	No	No	No	3	3
428	1x32	2x65	bombesin_on	0	1.0375	No	No	No	Yes	4	4
429	2x62	2x63	bombesin_on	0	0.99	No	No	No	Yes	4	5
430	5x60	5x63	bombesin_on	0	0.965	No	Yes	No	No	3	3
431	2x49	3x35	bombesin_on	0	0.93	No	No	No	No	8	8
432	4x48	4x51	bombesin_on	0	0.92	No	No	No	No	3	5
433	6x41	6x42	bombesin_on	0	0.92	No	No	No	No	7	5
434	1x42	7x43	bombesin_on	0	0.88	No	No	No	No	7	5
435	7x29	7x32	bombesin_on	0	0.88	No	No	No	No	2	1
436	4x47	4x48	bombesin_on	0	0.875	No	No	No	No	4	3
437	1x55	CT	bombesin_on	0	0.87	No	Yes	No	No	4	0
438	7x32	7x36	bombesin_on	0	0.855	No	No	No	No	1	4
439	I2x50	I2x51	bombesin_on	0	0.84	No	No	No	No	8	5
440	1x55	8x60	bombesin_on	0	0.81	No	Yes	No	No	4	0
441	4x41	I2x55	bombesin_on	0	0.805	No	No	No	No	4	5
442	3x53	I2x53	bombesin_on	0	0.805	No	No	No	No	8	6
443	1x51	1x54	bombesin_on	0	0.77	No	No	No	No	4	7
444	7x28	7x32	bombesin_on	0	0.76	No	No	No	No	3	1
445	5x41	5x42	bombesin_on	0	0.745	No	No	No	No	4	6
446	5x66	6x35	bombesin_on	0	0.725	No	No	No	No	4	6
447	8x56	8x57	bombesin_on	0	0.72	No	No	No	Yes	4	5
448	1x31	7x31	bombesin_on	0	0.63	No	No	No	Yes	4	4
449	3x52	3x56	bombesin_on	0	0.62	No	No	No	No	4	6

Orange: nodes, hubs and links specific of bombesin_off network

Green: nodes, hubs and links shared by both networks

Purple: nodes, hubs and links specific of bombesin_on network

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Owner: the name of the network the hub belong to or "Shared" if the corresponding hub is present in both networks.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub in the corresponding network.

Num Of Links: the number of links of the corresponding hub in the corresponding network.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Owner	bombesin_off Avg Int. Strength	bombesin_on Avg Int. Strength	bombesin_off Num Of Links	bombesin_on Num Of Links	ConSurf
1	1x43	bombesin_off	5.462	6.14	5	2	7
2	1x50	bombesin_off	6.7425	4.74625	4	2	9
3	1x60	bombesin_off	3.815	5.17	4	3	6
4	3x30	bombesin_off	4.51	2.80083	4	3	6
5	3x39	bombesin_off	8.22	5.89	4	1	9
6	3x41	bombesin_off	5.13	4.07	4	3	5
7	3x42	bombesin_off	5.155	6.3725	4	2	8
8	3x50	bombesin_off	6.8475	4.63	4	1	9
9	3x51	bombesin_off	8.59	10.2217	4	3	8
10	4x50	bombesin_off	7.63	9.45667	4	3	9
11	6x48	bombesin_off	7.634	11.625	5	3	8
12	6x51	bombesin_off	4.6225	6.50917	4	3	5
13	7x46	bombesin_off	5.975	8.18	4	2	8
14	7x54	bombesin_off	7.1875	8.67667	4	3	7
15	8x54	bombesin_off	8.9025	7.90917	4	3	7
16	2x38	Shared	4.492	2.67375	5	4	7
17	2x42	Shared	5.17167	4.6245	6	5	7
18	2x50	Shared	8.0375	5.7005	4	5	9
19	2x64	Shared	6.025	6.121	4	5	4
20	E1x50	Shared	5.95143	7.124	7	5	8
21	E2	Shared	18.7392	13.5185	13	17	3
22	5x47	Shared	7.226	6.99125	5	4	8
23	5x58	Shared	7.794	6.1875	5	5	8
24	6x55	Shared	11.34	5.465	4	4	5
25	E3	Shared	9.52111	9.57708	9	12	3
26	7x42	Shared	7.37	4.1425	4	5	7
27	7x45	Shared	6.7	5.279	4	5	9
28	8x50	Shared	7.98	4.115	4	6	9
29	Lig	Shared	10.6869	11.2539	13	23	0
30	1x39	bombesin_on	12.6533	4.8825	3	5	7
31	1x55	bombesin_on	7.53	4.7	2	4	4
32	1x57	bombesin_on	4.81	5.6775	3	4	7
33	2x46	bombesin_on	5.76	5.61938	2	4	9
34	2x56	bombesin_on	4.58	5.7315	1	5	7
35	2x59	bombesin_on	2.92	3.8225	1	4	6
36	2x60	bombesin_on	7.78	4.83563	2	4	6
37	2x63	bombesin_on	6	7.72438	1	4	5
38	2x65	bombesin_on	1.17	1.38625	1	4	4
39	E1x52	bombesin_on	7.77333	5.86812	3	4	7
40	3x28	bombesin_on	4.34	4.37375	2	4	5
41	3x32	bombesin_on	6.36	6.03125	3	4	6
42	3x43	bombesin_on	4.15	4.61875	1	4	9
43	4x61	bombesin_on	10.6	4.34333	3	6	5
44	5x34	bombesin_on	2.26	4.13937	1	4	1
45	5x39	bombesin_on	6.45	4.4	3	5	5
46	5x43	bombesin_on	7.19667	4.63062	3	4	6
47	5x57	bombesin_on	5.97	6.575	3	4	7
48	5x60	bombesin_on	5.34333	3.17313	3	4	3
49	5x65	bombesin_on	3.31	3.251	3	5	8
50	6x27	bombesin_on	3.1	3.45125	1	4	4
51	6x30	bombesin_on	8.635	3.2385	2	5	7
52	6x44	bombesin_on	9.34	7.62375	3	4	9
53	6x52	bombesin_on	6.95	7.78062	3	4	7
54	6x54	bombesin_on	4.56	3.99125	1	4	5
55	6x58	bombesin_on	4.12	5.75875	1	4	4
56	6x59	bombesin_on	5.805	4.17375	2	4	4
57	7x30	bombesin_on	6.63333	6.54813	3	4	4
58	7x31	bombesin_on	10.05	6.97375	1	4	4
59	7x34	bombesin_on	6.97	4.42688	1	4	4
60	7x38	bombesin_on	10.15	5.086	1	5	5
61	7x49	bombesin_on	5.72667	4.612	3	5	9
62	8x57	bombesin_on	8.84	7.065	2	4	5

Orange: nodes, hubs and links specific of bombesin_off network

Green: nodes, hubs and links shared by both networks

Purple: nodes, hubs and links specific of bombesin_on network

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Owner: the name of the network the link belong to or "Shared" if the corresponding link is present in both networks.

Recurrence: the relative Recurrence in the filtered pool of shortest paths.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Owner	bombesin_off Recurrence	bombesin_on Recurrence	bombesin_off Hub1?	bombesin_on Hub1?	bombesin_off Hub2?	bombesin_on Hub2?	ConSurf1	ConSurf2
1	1x42	7x42	bombesin_off	11.6649	0	No	No	Yes	Yes	7	7
2	1x43	2x54	bombesin_off	23.646	0	Yes	No	No	No	7	6
3	2x54	7x46	bombesin_off	24.9407	2.69511	No	No	Yes	No	6	8
4	1x50	2x50	bombesin_off	23.1414	4.03387	Yes	No	Yes	Yes	9	9
5	1x50	2x47	bombesin_off	13.3974	0	Yes	No	No	No	9	9
6	2x50	7x49	bombesin_off	28.4481	8.37345	Yes	Yes	No	Yes	9	9
7	6x40	7x49	bombesin_off	49.2189	0	No	No	No	Yes	7	9
8	6x40	7x53	bombesin_off	37.5236	0	No	No	No	No	7	9
9	7x53	8x50	bombesin_off	35.086	1.10686	No	No	Yes	Yes	9	9
10	8x50	8x54	bombesin_off	20.5641	7.60392	Yes	Yes	Yes	No	9	7
11	1x54	2x47	bombesin_off	11.9567	2.2102	No	No	No	No	7	9
12	3x39	7x46	bombesin_off	23.9134	0	Yes	No	Yes	No	9	8
13	3x39	6x44	bombesin_off	95.1128	0	Yes	No	No	Yes	9	9
14	3x40	6x44	bombesin_off	91.3075	0	No	No	No	Yes	8	9
15	3x40	3x41	bombesin_off	89.338	7.94125	No	No	Yes	No	8	5
16	3x41	4x49	bombesin_off	81.9829	1.15254	Yes	No	No	No	5	7
17	3x42	4x49	bombesin_off	81.1805	0	Yes	No	No	No	8	7
18	2x42	3x42	bombesin_off	74.3237	0	Yes	Yes	Yes	No	7	8
19	2x38	2x42	bombesin_off	29.5666	0	Yes	Yes	Yes	Yes	7	7
20	2x38	3x49	bombesin_off	24.965	0	Yes	Yes	No	No	7	8
21	2x39	3x49	bombesin_off	17.7132	0	No	No	No	No	8	8
22	2x37	2x39	bombesin_off	17.0324	2.2102	No	No	No	No	8	8
23	2x37	2x40	bombesin_off	15.3608	1.10686	No	No	No	No	8	8
24	2x40	I1x50	bombesin_off	13.677	0	No	No	No	No	8	7
25	1x60	I1x50	bombesin_off	12.2059	2.19614	Yes	No	No	No	6	7
26	3x49	3x50	bombesin_off	10.4067	0	No	No	Yes	No	8	9
27	3x46	6x37	bombesin_off	40.3623	0	No	No	No	No	9	8
28	3x50	6x37	bombesin_off	12.3518	0	Yes	No	No	No	9	8
29	6x48	Lig	bombesin_off	96.5473	0	Yes	No	Yes	Yes	8	0
30	3x32	Lig	bombesin_off	11.1847	8.62645	No	Yes	Yes	Yes	6	0
31	E1x50	E2	bombesin_off	14.2848	0	Yes	Yes	Yes	Yes	8	3
32	3x33	4x57	bombesin_off	12.4795	6.42679	No	No	No	No	4	7
33	3x30	4x57	bombesin_off	10.9355	5.15478	Yes	No	No	No	6	7
34	3x39	7x45	bombesin_off	30.8431	0	Yes	No	Yes	Yes	9	9
35	3x41	5x46	bombesin_off	11.1422	0	Yes	No	No	No	5	6
36	5x58	5x61	bombesin_off	26.8616	0	Yes	Yes	No	No	8	8
37	3x51	5x61	bombesin_off	17.7801	0	Yes	No	No	No	8	8
38	3x50	3x53	bombesin_off	11.3489	0	Yes	No	No	No	9	8
39	E2	E3	bombesin_off	16.072	1.31066	Yes	Yes	Yes	Yes	3	3
40	5x35	Lig	bombesin_off	16.0598	0	No	No	Yes	Yes	3	0
41	5x35	E3	bombesin_off	14.8806	0	No	No	Yes	Yes	3	3
42	6x55	Lig	bombesin_off	12.3883	3.16244	Yes	Yes	Yes	Yes	5	0
43	6x36	6x40	bombesin_off	10.0115	4.42391	No	No	No	No	8	7
44	7x30	E3	bombesin_off	14.3213	0.509505	No	Yes	Yes	Yes	4	3
45	7x54	8x54	bombesin_off	12.9415	4.3958	Yes	No	Yes	No	7	7
46	1x43	7x42	bombesin_off	14.2788	0	Yes	No	Yes	Yes	7	7
47	2x50	3x39	bombesin_off	42.5202	1.34931	Yes	Yes	Yes	No	9	9
48	2x42	3x46	Shared	41.4504	13.8831	Yes	Yes	No	No	7	9
49	6x44	6x48	Shared	100	47.152	No	Yes	Yes	No	9	8
50	E2	Lig	Shared	42.7877	17.9592	Yes	Yes	Yes	Yes	3	0
51	4x61	Lig	Shared	15.4094	15.6049	No	Yes	Yes	Yes	5	0
52	3x33	4x61	Shared	14.0113	13.6126	No	No	No	Yes	4	5
53	5x58	6x37	Shared	36.6543	27.0494	Yes	Yes	No	No	8	8
54	6x52	Lig	Shared	20.0413	95.6534	No	Yes	Yes	Yes	7	0
55	5x47	6x52	Shared	10.8869	10.4958	Yes	Yes	No	Yes	8	7
56	7x45	7x49	Shared	24.3754	45.4232	Yes	Yes	No	Yes	9	9
57	1x35	7x35	bombesin_on	0	21.2657	No	No	No	No	6	4
58	2x64	7x35	bombesin_on	0	11.947	Yes	Yes	No	No	4	4
59	2x64	Lig	bombesin_on	0	14.0061	Yes	Yes	Yes	Yes	4	0
60	7x42	Lig	bombesin_on	0	13.4966	Yes	Yes	Yes	Yes	7	0
61	7x31	7x35	bombesin_on	0	11.3005	No	Yes	No	No	4	4
62	7x31	Lig	bombesin_on	0	13.1206	No	Yes	Yes	Yes	4	0
63	6x48	6x52	bombesin_on	0	100	Yes	No	No	Yes	8	7
64	6x48	7x45	bombesin_on	0	55.2584	Yes	No	Yes	Yes	8	9
65	7x49	7x50	bombesin_on	0	50.7607	No	Yes	No	No	9	9
66	1x53	7x50	bombesin_on	0	43.9931	No	No	No	No	9	9
67	1x53	2x43	bombesin_on	2.59559	40.8026	No	No	No	No	9	8
68	1x57	2x43	bombesin_on	0	27.8155	No	Yes	No	No	7	8
69	1x57	8x50	bombesin_on	0	24.0662	No	Yes	Yes	Yes	7	9
70	2x43	3x46	bombesin_on	0	14.9021	No	No	No	No	8	9
71	3x43	6x44	bombesin_on	0	28.455	No	Yes	No	Yes	9	9
72	2x46	3x43	bombesin_on	1.623	17.7062	No	Yes	No	Yes	9	9
73	2x46	3x42	bombesin_on	3.23992	22.6958	No	Yes	Yes	No	9	8
74	2x45	3x42	bombesin_on	8.01775	20.4575	No	No	Yes	No	9	8
75	2x45	4x50	bombesin_on	6.4373	15.9598	No	No	Yes	No	9	9
76	2x63	Lig	bombesin_on	0	10.7769	No	Yes	Yes	Yes	5	0
77	3x38	4x50	bombesin_on	1.623	11.434	No	No	Yes	No	7	9
78	5x54	6x44	bombesin_on	0	56.4215	No	No	No	Yes	8	9
79	3x47	5x54	bombesin_on	4.99058	55.7082	No	No	No	No	9	8
80	3x47	5x57	bombesin_on	0	27.6257	No	No	No	Yes	9	7
81	5x53	5x57	bombesin_on	1.67163	13.4052	No	No	No	Yes	7	7
82	5x49	5x53	bombesin_on	0	11.2407	No	No	No	No	5	7
83	5x49	5x50	bombesin_on	1.623	10.1479	No	No	No	No	5	9
84	3x47	5x58	bombesin_on	6.63182	34.1122	No	No	Yes	Yes	9	8
85	3x51	5x57	bombesin_on	4.99058	13.2612	Yes	No	No	Yes	8	7
86	5x61	6x37	bombesin_on	0	26.0445	No	No	No	No	8	8
87	E3	Lig	bombesin_on	0	14.0377	Yes	Yes	Yes	Yes	3	0
88	5x61	5x65	bombesin_on	8.2609	24.1294	No	No	No	Yes	8	8
89	5x65	6x30	bombesin_on	0	19.0906	No	Yes	No	Yes	8	7
90	6x27	6x30	bombesin_on	0	13.212	No	Yes	No	Yes	4	7
91	1x32	2x65	bombesin_on	0	10.9385	No	No	No	Yes	4	4
92	1x36	2x65	bombesin_on	0	17.2705	No	No	No	Yes	6	4
93	1x35	1x36	bombesin_on	0	19.4209	No	No	No	No	6	6
94	3x24	E1x52	bombesin_on	0	12.2668	No	No	No	Yes	6	7
95	3x43	7x49	bombesin_on	0	15.6682	No	Yes	No	Yes	9	9

Here, those paths that begin and end at given residue pair(s) or that pass through a residue are used to generate a novel metapath. Such a path filtering is particularly recommended if some information on allosteric residues is available. The selection syntax for a residue pair ("Pairs") is C:C:c534,A:A:?600 (the lower-case "c" stands for cytosine and "?" indicates any non standard amino acid or nucleotide residue). Selection of more than one apical residue pair has the following syntax: C:C:c534,A:A:?600,C:C:c534,A:A:E41. Only one residue can be selected as a tail ("Tail"). For midway residue(s), each residue must be separated by a comma as well e.g. A:A:?600,A:A:E41.

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Node1	Node2	Owner	Net1LinkStrength	Net2LinkStrength	Comm1	Comm2	Node1Shell	Node2Shell
1x35	2x64	bombesin_off	9.67	0	0	0	2	1
1x36	2x64	bombesin_off	9.74	0	0	0	2	1
1x39	1x43	Shared	10.88	6.045	2	1	2	2
1x39	2x60	Shared	12.64	3.1625	2	1	2	2
1x39	7x42	Shared	14.44	6.19	2	1	2	1
1x42	7x42	bombesin_off	6.28	0	0	0	2	1
1x43	7x42	bombesin_off	7.54	0	2	0	2	1
2x53	3x35	Shared	6.01	3.75	0	1	1	2
2x53	7x46	bombesin_off	4.5	0	0	1	1	2
2x551	3x28	bombesin_off	4.56	0	0	0	2	2
2x56	3x32	Shared	4.58	10.68	0	1	1	1
2x63	E1x50	Shared	6	8.5	0	1	1	2
E1	E2	Shared	12.78	8.06	0	1	1	1
E1x49	E2	bombesin_off	4.28	0	1	0	2	1
3x25	E1x50	Shared	3.92	3.265	1	1	2	2
E1x50	E2	bombesin_off	4.56	0	1	1	2	1
E1x50	E2x50	Shared	6.53	11.425	1	1	2	1
3x22	E2	Shared	19.17	8.59	0	1	2	1
3x25	E2	Shared	4.76	3.295	1	1	2	1
3x25	E2x50	Shared	7.28	7.28	1	1	2	1
3x26	E2	bombesin_off	9.68	0	1	0	2	1
3x28	3x32	Shared	4.12	4.12	0	1	2	1
3x29	4x61	bombesin_off	6.29	0	1	1	1	1
3x29	4x65	Shared	5.34	3.1175	1	1	1	1
3x29	Lig	Shared	10.97	16.0175	1	1	1	0
3x32	Lig	Shared	10.38	4.31	0	1	1	0
3x33	4x61	Shared	9.28	3.645	0	0	2	1
3x36	6x48	bombesin_off	4.9	0	0	0	1	1
4x61	Lig	Shared	16.23	5.5375	1	1	1	0
4x65	E2x52	bombesin_off	5.34	0	0	1	1	1
E2	E2	Shared	74.67	38.0075	1	1	1	1
E2	E2x51	Shared	4.39	8.355	1	1	1	2
E2	E2x52	Shared	5.56	12.52	1	1	1	1
E2x52	Lig	Shared	15.54	20.4075	1	1	1	0
6x58	E2	bombesin_off	4.12	0	0	1	2	1
E2	E3	Shared	11.91	28.025	1	1	1	1
E2	Lig	Shared	13.06	37.2625	1	1	1	0
5x29	E3	Shared	9.76	11.1625	0	1	2	1
5x32	E3	bombesin_off	18.27	0	0	0	2	1
5x35	E3	bombesin_off	6.95	0	1	1	1	1
5x35	Lig	bombesin_off	8.23	0	1	1	1	0
5x38	5x42	Shared	4.18	4.91	1	0	1	2
5x38	6x55	bombesin_off	6.53	0	1	0	1	1
5x38	Lig	bombesin_off	7.16	0	1	0	1	0
5x39	6x59	Shared	6.52	3.26	0	1	2	2
5x42	6x55	bombesin_off	7.63	0	1	0	2	1
5x43	5x47	Shared	8.25	4.125	1	1	2	2
5x43	6x52	Shared	6.79	4.8075	1	1	2	1
5x47	6x52	Shared	7.62	12.335	1	1	2	1
6x44	6x48	Shared	14.03	15.535	0	0	2	1
6x48	6x51	bombesin_off	4.52	0	1	0	1	1
6x48	7x41	bombesin_off	6.48	0	1	0	1	2
6x48	Lig	bombesin_off	8.24	0	1	0	1	0
6x51	7x37	bombesin_off	4.69	0	1	1	1	2
6x51	7x41	Shared	4.69	7.205	1	1	1	2
6x51	Lig	Shared	4.59	7.8025	1	1	1	0
6x52	Lig	Shared	6.44	7.635	1	1	1	0
6x54	7x33	Shared	4.56	2.265	0	1	2	2
6x55	6x59	Shared	5.09	6.0425	1	1	1	2
6x55	Lig	Shared	26.11	7.465	1	1	1	0
6x57	6x61	Shared	28.31	7.915	0	1	2	2
6x61	E3	Shared	8.62	4.3175	1	1	2	1
E3	E3	Shared	7	17.495	1	1	1	1
7x27	E3	Shared	7.36	2.945	0	1	2	1
7x30	E3	Shared	8.82	4.725	1	1	1	1
7x30	7x33	bombesin_off	4.11	0	1	1	1	2
7x30	7x34	Shared	6.97	6.225	1	1	1	2
7x31	7x35	Shared	10.05	7.305	0	1	1	2
7x38	Lig	Shared	10.15	5.8725	0	1	1	0
1x32	2x64	bombesin_off	3.52	0	0	0	2	1
2x59	2x60	bombesin_off	2.92	0	0	1	2	2
4x64	5x34	Shared	2.26	6.2225	0	0	2	2
5x28	Lig	bombesin_off	1.83	0	0	0	1	0
5x28	5x31	bombesin_off	1.63	0	0	0	1	2
5x30	5x31	bombesin_off	1.49	0	0	0	2	2
1x31	1x32	bombesin_off	1.43	0	0	0	2	2
7x39	7x42	bombesin_off	1.22	0	0	0	2	1
2x64	2x65	bombesin_off	1.17	0	0	1	1	2
1x35	1x36	bombesin_on	0	3.39	0	0	2	2
1x35	7x35	bombesin_on	0	4.6725	0	0	2	2
1x39	7x39	bombesin_on	0	7.12	2	1	2	2
1x43	2x57	bombesin_on	0	6.235	2	0	2	2
2x53	2x56	bombesin_on	0	3.965	0	1	1	1
2x56	7x42	bombesin_on	0	3.84	0	1	1	1
2x56	Lig	bombesin_on	0	7.6375	0	1	1	0
2x57	7x42	bombesin_on	0	3.39	0	0	2	1
2x59	2x63	bombesin_on	0	3.9225	0	1	2	1
2x59	3x28	bombesin_on	0	3.075	0	1	2	2
2x59	3x32	bombesin_on	0	5.015	0	1	2	1
2x60	2x64	bombesin_on	0	5.7475	0	1	2	1
2x60	7x38	bombesin_on	0	6.55	0	1	2	1
2x63	Lig	bombesin_on	0	17.485	0	1	1	0
2x64	7x31	bombesin_on	0	4.6325	0	1	1	1
2x64	7x34	bombesin_on	0	3.465	0	1	1	2
2x64	7x35	bombesin_on	0	4.46	0	1	1	2
2x64	Lig	bombesin_on	0	12.3	0	1	1	0
E1	Lig	bombesin_on	0	5.0525	0	1	1	0
3x22	3x26	bombesin_on	0	3.2925	0	1	2	2
3x28	3x29	bombesin_on	0	3.39	0	1	2	1
3x36	Lig	bombesin_on	0	5.585	0	0	1	0
4x61	4x65	bombesin_on	0	3.59	1	1	1	1
4x61	E2x52	bombesin_on	0	5.8975	1	1	1	1
4x61	5x38	bombesin_on	0	3.695	1	1	1	1
4x65	Lig	bombesin_on	0	6.625	0	1	1	0
5x28	E2	bombesin_on	0	3.745	0	0	1	1
5x29	E2	bombesin_on	0	9.0575	0	1	2	1
E2x50	Lig	bombesin_on	0	5.175	1	1	1	0
5x34	E2	bombesin_on	0	3.81	0	1	2	1
5x35	E2	bombesin_on	0	8.44	1	1	1	1
6x55	E2	bombesin_on	0	4.7175	1	1	1	1
6x59	E2	bombesin_on	0	4.1325	0	1	2	1
5x31	5x34	bombesin_on	0	3.19	0	0	2	2
5x34	5x38	bombesin_on	0	3.335	0	1	2	1
5x39	6x55	bombesin_on	0	3.635	0	1	2	1
6x48	6x52	bombesin_on	0	6.345	1	0	1	1
6x48	7x45	bombesin_on	0	12.995	1	0	1	2
6x51	7x38	bombesin_on	0	4.52	1	1	1	1
6x54	6x58	bombesin_on	0	6.165	0	1	2	2
6x54	7x34	bombesin_on	0	4.1125	0	1	2	2
6x54	7x38	bombesin_on	0	3.4225	0	1	2	1
6x57	E3	bombesin_on	0	4.3125	0	1	2	1
6x58	7x30	bombesin_on	0	7.9	0	1	2	1
6x58	7x34	bombesin_on	0	3.905	0	1	2	2
6x58	7x38	bombesin_on	0	5.065	0	1	2	1
E3	Lig	bombesin_on	0	8.6975	1	1	1	0
7x30	Lig	bombesin_on	0	7.3425	1	1	1	0
7x31	Lig	bombesin_on	0	15.3275	0	1	1	0
7x42	Lig	bombesin_on	0	3.41	2	1	1	0
2x53	Lig	bombesin_on	0	3.1825	0	1	1	0
2x60	7x42	bombesin_on	0	3.8825	0	1	2	1
4x61	5x39	bombesin_on	0	3.695	1	1	1	2
4x64	5x35	bombesin_on	0	12.445	0	0	2	1
5x36	E2	bombesin_on	0	8.345	0	1	2	1
5x39	E2	bombesin_on	0	5.445	0	1	2	1
5x33	E3	bombesin_on	0	8.24	0	0	2	1
5x36	E3	bombesin_on	0	4.87	0	1	2	1
5x39	5x43	bombesin_on	0	5.965	0	1	2	2
5x30	E3	bombesin_on	0	2.64	0	0	2	1
2x551	2x56	bombesin_on	0	2.535	0	0	2	1
E1	E1x49	bombesin_on	0	2.435	0	1	1	2
1x36	2x65	bombesin_on	0	2.0525	0	0	2	2
5x32	5x35	bombesin_on	0	1.26	0	0	2	1
1x32	2x65	bombesin_on	0	1.0375	0	0	2	2
2x62	2x63	bombesin_on	0	0.99	0	0	2	1
1x31	7x31	bombesin_on	0	0.63	0	0	2	1

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Difference Members
	Id	Description
	bombesin_off	bb2_off
	bombesin_on	bb2_on bb1_on

Network Difference
Value	bombesin_off	bombesin_on
I_min	3.89	3.0725
Number of Linked Nodes	249	278
Number of Specific Nodes	3 (1.20%)	32 (11.51%)
Number of Shared Nodes	246 (98.80%)	246 (88.49%)
Number of Links	261	329
Number of Specific Links	120 (45.98%)	188 (57.14%)
Number of Shared Links	141 (54.02%)	141 (42.86%)
Number of Hubs	29	47
Number of Specific Hubs	15 (51.72%)	33 (70.21%)
Number of Shared Hubs	14 (48.28%)	14 (29.79%)
Average % Shared Neighbours (Jaccard)	32.84
Average % Shared Neighbours (Otsuka)	42.54
Average % Shared Neighbours (Overlap Coefficient)	53.08
Average % Shared Cliques (k3-6)	51.67
Graphlets Similarity	0.525259

Paths Difference
Value	bombesin_off	bombesin_on
Number Of Nodes in MetaPath	54	48
Specific Nodes in MetaPath	34 (62.96%)	28 (58.33%)
Shared Nodes in MetaPath	246 (98.80%)	246 (98.80%)
Number Of Links MetaPath	56	48
Specific Links in MetaPath	47 (83.93%)	39 (81.25%)
Shared Links in MetaPath	141 (54.02%)	141 (54.02%)
Number of Shortest Paths	33342	52489
Length Of Smallest Path	3	3
Average Path Length	12.2519	11.627
Length of Longest Path	27	26
Minimum Path Strength	1.405	0.8075
Average Path Strength	7.171	6.13769
Maximum Path Strength	21.17	23.16
Minimum Path Correlation	0.7	0.7
Average Path Correlation	0.921409	0.930365
Maximum Path Correlation	0.99	0.99
Minimum % Of Corr. Nodes	4.7619	4.7619
Average % Of Corr. Nodes	53.9302	54.5886
Maximum % Of Corr. Nodes	100	100
Minimum Path Hubs %	0	0
Average Path Hubs %	43.0212	46.1374
Maximum Path Hubs %	100	100

Details about the values in these tables can be found in the corresponding documentation page .

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