Orange: nodes, hubs and links specific of cb1_on_gp network

Green: nodes, hubs and links shared by both networks

Purple: nodes, hubs and links specific of cb1_off network

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Owner: the name of the network the hub belong to or "Shared" if the corresponding hub is present in both networks.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub in the corresponding network.

Num Of Links: the number of links of the corresponding hub in the corresponding network.

ConSurf: this column reports the ConSurf conservation grades of each hub.


Index Hub Owner cb1_on_gp Avg Int. Strength cb1_off Avg Int. Strength cb1_on_gp Num Of Links cb1_off Num Of Links ConSurf
1G.HN.30 cb1_on_gp00407
2G.S1.02 cb1_on_gp500405
3G.H1.01 cb1_on_gp500409
4G.S2.08 cb1_on_gp500405
5G.S3.01 cb1_on_gp500404
6G.S3.03 cb1_on_gp1000607
7G.S3.04 cb1_on_gp500506
8G.S3.05 cb1_on_gp1000507
9G.S3.06 cb1_on_gp500605
10G.s3h2.03 cb1_on_gp1000409
11G.H2.01 cb1_on_gp00409
12G.H2.06 cb1_on_gp1000509
13G.H2.07 cb1_on_gp1000709
14G.H2.09 cb1_on_gp00408
15G.h2s4.01 cb1_on_gp500609
16G.h2s4.02 cb1_on_gp00407
17G.S4.02 cb1_on_gp500408
18G.S4.03 cb1_on_gp1000407
19G.S4.04 cb1_on_gp500509
20G.S4.05 cb1_on_gp500407
21G.S4.07 cb1_on_gp500408
22G.s4h3.04 cb1_on_gp1000508
23G.H3.01 cb1_on_gp500509
24G.H3.09 cb1_on_gp1000709
25G.H3.13 cb1_on_gp500505
26G.H3.14 cb1_on_gp500408
27G.H3.17 cb1_on_gp1000605
28G.H3.18 cb1_on_gp500409
29G.S5.04 cb1_on_gp500509
30G.S5.05 cb1_on_gp500709
31G.S5.07 cb1_on_gp00409
32G.s5hg.01 cb1_on_gp00409
33G.HG.01 cb1_on_gp500505
34G.HG.04 cb1_on_gp500409
35G.HG.07 cb1_on_gp500409
36G.HG.15 cb1_on_gp1000407
37G.hgh4.02 cb1_on_gp1000507
38G.hgh4.05 cb1_on_gp1000607
39G.H4.03 cb1_on_gp500404
40G.H4.07 cb1_on_gp500405
41G.H4.08 cb1_on_gp500403
42G.H4.10 cb1_on_gp1000606
43G.H4.12 cb1_on_gp500505
44G.H4.15 cb1_on_gp500408
45G.S6.02 cb1_on_gp1000507
46G.S6.04 cb1_on_gp00409
47G.S6.05 cb1_on_gp1000504
48G.s6h5.01 cb1_on_gp1000409
49G.s6h5.05 cb1_on_gp500409
50G.H5.03 cb1_on_gp1000508
51G.H5.08 cb1_on_gp1000508
52G.H5.13 cb1_on_gp500408
53b.1x3 cb1_on_gp00401
54b.1x4 cb1_on_gp00508
55b.1x11 cb1_on_gp500508
56b.h2x1 cb1_on_gp500505
57b.lhb1x6 cb1_on_gp00403
58b.b1x6 cb1_on_gp1000409
59b.l1x3 cb1_on_gp1000509
60b.l1x6 cb1_on_gp500409
61b.b2x1 cb1_on_gp500608
62b.b2x5 cb1_on_gp1000707
63b.b3x3 cb1_on_gp1000408
64b.l3x1 cb1_on_gp500409
65b.l3x2 cb1_on_gp500409
66b.b4x2 cb1_on_gp500408
67b.b4x3 cb1_on_gp500407
68b.b4x5 cb1_on_gp500407
69b.b4x6 cb1_on_gp1000609
70b.b4x7 cb1_on_gp500408
71b.l4x2 cb1_on_gp00404
72b.l4x3 cb1_on_gp500406
73b.b5x2 cb1_on_gp500407
74b.b5x3 cb1_on_gp1000609
75b.b5x5 cb1_on_gp500405
76b.b5x7 cb1_on_gp1000407
77b.l5x1 cb1_on_gp1000408
78b.l5x5 cb1_on_gp1000709
79b.b6x5 cb1_on_gp1000606
80b.l6x5 cb1_on_gp1000404
81b.b7x1 cb1_on_gp1000504
82b.b7x2 cb1_on_gp500408
83b.b8x1 cb1_on_gp500408
84b.b8x3 cb1_on_gp1000506
85b.b8x4 cb1_on_gp1000506
86b.l8x5 cb1_on_gp00403
87b.b9x4 cb1_on_gp500409
88b.l9x3 cb1_on_gp1000509
89b.l9x6 cb1_on_gp1000908
90b.l9x7 cb1_on_gp500407
91b.b10x4 cb1_on_gp1000406
92b.b10x5 cb1_on_gp1000709
93b.l10x1 cb1_on_gp00403
94b.b11x2 cb1_on_gp1000407
95b.b11x4 cb1_on_gp1000609
96b.l11x2 cb1_on_gp1000409
97b.b12x3 cb1_on_gp1000408
98b.b12x5 cb1_on_gp500406
99b.b12x6 cb1_on_gp500508
100b.b13x3 cb1_on_gp00404
101b.b13x7 cb1_on_gp1000507
102b.l13x3 cb1_on_gp1000509
103b.l13x6 cb1_on_gp500509
104b.l13x7 cb1_on_gp500409
105b.b14x3 cb1_on_gp500505
106b.b15x1 cb1_on_gp1000509
107b.b15x3 cb1_on_gp500409
108b.l15x1 cb1_on_gp500407
109b.l15x2 cb1_on_gp1000409
110b.b16x4 cb1_on_gp1000406
111b.b16x5 cb1_on_gp1000405
112b.b16x6 cb1_on_gp1000608
113b.b16x7 cb1_on_gp500409
114b.b17x3 cb1_on_gp500405
115b.b17x7 cb1_on_gp1000408
116b.l17x3 cb1_on_gp1000609
117b.l17x6 cb1_on_gp1000409
118b.b18x3 cb1_on_gp00408
119b.b18x5 cb1_on_gp500505
120b.l18x1 cb1_on_gp1000706
121b.l18x3 cb1_on_gp00405
122b.b19x2 cb1_on_gp500606
123b.b19x4 cb1_on_gp1000408
124b.l19x1 cb1_on_gp500409
125b.l19x2 cb1_on_gp1000509
126b.b20x2 cb1_on_gp500406
127b.b20x4 cb1_on_gp1000508
128b.b20x6 cb1_on_gp1000506
129b.b20x7 cb1_on_gp500509
130b.b21x1 cb1_on_gp1000507
131b.b21x5 cb1_on_gp500404
132b.b21x7 cb1_on_gp1000505
133b.l21x2 cb1_on_gp00404
134b.b22x5 cb1_on_gp1000807
135b.l22x5 cb1_on_gp500409
136b.b23x2 cb1_on_gp500406
137b.b23x6 cb1_on_gp1000607
138b.l23x1 cb1_on_gp500406
139b.l24x2 cb1_on_gp00406
140b.l24x3 cb1_on_gp500405
141b.l25x3 cb1_on_gp1000509
142b.l25x6 cb1_on_gp1000508
143b.l27x1 cb1_on_gp1000809
144b.l27x2 cb1_on_gp1000409
145b.b28x3 cb1_on_gp1000407
146b.b28x4 cb1_on_gp1000406
147b.b28x5 cb1_on_gp1000405
148b.b28x6 cb1_on_gp1000509
149g.h1x10 cb1_on_gp00409
150g.h1x11 cb1_on_gp00409
151g.h2x15 cb1_on_gp00406
152g.ctx3 cb1_on_gp500609
153g.ctx6 cb1_on_gp500406
1541x60 cb1_on_gp00426
1552x50 cb1_on_gp1000539
1562x64 cb1_on_gp1000634
1572x65 cb1_on_gp500524
1583x22 cb1_on_gp1000633
1593x33 cb1_on_gp00426
160E2.N256 cb1_on_gp00536
161E2.I271 cb1_on_gp500633
1625x39 cb1_on_gp10050737
1635x60 cb1_on_gp10050534
1646x32 cb1_on_gp00417
1656x52 cb1_on_gp00427
1666x55 cb1_on_gp10050436
167E3.K370 cb1_on_gp00411
1687x52 cb1_on_gp1000429
1698x50 cb1_on_gp1000528
1701x39 Shared500447
1711x46 Shared500447
1722x37 Shared00445
1732x40 Shared100100659
1742x46 Shared500449
1752x57 Shared100100467
1762x61 Shared10050655
1773x36 Shared50100467
1783x50 Shared100100569
179I2x53 Shared100100567
1804x50 Shared0100469
181E2.W255 Shared50100445
182E2.F268 Shared50100445
183E2.H270 Shared0100453
1845x43 Shared100100666
1855x58 Shared10050669
1866x48 Shared50100548
1876x51 Shared050447
1887x34 Shared100100644
1897x49 Shared5050449
1907x53 Shared10050649
191Lig Shared10010016120
192NT.N101 cb1_off050040
193NT.F102 cb1_off0100050
194NT.M103 cb1_off0100050
195NT.F108 cb1_off5050255
196NT.L111 cb1_off050244
1971x28 cb1_off00356
1981x49 cb1_off00258
1991x56 cb1_off00348
2002x42 cb1_off050348
2013x25 cb1_off50100349
2023x28 cb1_off050256
2033x49 cb1_off5050349
2043x56 cb1_off00145
205I2x57 cb1_off5050246
206E2.E258 cb1_off0100341
207E2.I267 cb1_off50100344
2085x36 cb1_off500345
2095x64 cb1_off500345
2106x31 cb1_off00145
2116x58 cb1_off050244
2126x59 cb1_off00244
2137x30 cb1_off00143
2147x45 cb1_off0100359
2157x47 cb1_off00357
   
Orange: nodes, hubs and links specific of cb1_on_gp network

Green: nodes, hubs and links shared by both networks

Purple: nodes, hubs and links specific of cb1_off network

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Owner: the name of the network the link belong to or "Shared" if the corresponding link is present in both networks.

Recurrence: the relative Recurrence in the filtered pool of shortest paths.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.


Index Node1 Node2 Owner cb1_on_gp Recurrence cb1_off Recurrence cb1_on_gp Hub1? cb1_off Hub1? cb1_on_gp Hub2? cb1_off Hub2? ConSurf1 ConSurf2
1b.b3x6 b.l1x3 cb1_on_gp20.88410NoNoYesNo99
2b.b3x6 b.l3x2 cb1_on_gp21.03080NoNoYesNo99
3b.b4x6 b.l1x3 cb1_on_gp18.76680YesNoYesNo99
4b.l1x4 b.l3x2 cb1_on_gp23.5150NoNoYesNo69
5G.hns1.01 b.l1x4 cb1_on_gp24.2420NoNoNoNo36
6G.S1.03 G.hns1.01 cb1_on_gp24.38890NoNoNoNo93
7b.b10x1 b.b11x5 cb1_on_gp11.07320NoNoNoNo96
8b.b10x1 b.l9x6 cb1_on_gp11.16140NoNoYesNo98
9G.H2.07 b.l9x6 cb1_on_gp77.37140YesNoYesNo98
10G.H2.04 G.H2.07 cb1_on_gp89.95350NoNoYesNo99
11G.H2.04 G.H3.08 cb1_on_gp90.01720NoNoNoNo99
12G.H3.08 G.S4.04 cb1_on_gp90.0510NoNoYesNo99
13G.H3.09 G.S4.04 cb1_on_gp34.7830YesNoYesNo99
14G.H3.09 G.H4.15 cb1_on_gp34.52910YesNoYesNo98
15G.H3.06 G.H4.15 cb1_on_gp68.65040NoNoYesNo68
16G.H3.06 G.hgh4.02 cb1_on_gp68.12430NoNoYesNo67
17G.hgh4.01 G.hgh4.02 cb1_on_gp66.45230NoNoYesNo67
18G.hgh4.01 G.s4h3.04 cb1_on_gp66.27640NoNoYesNo68
19G.HG.07 G.s4h3.04 cb1_on_gp1000YesNoYesNo98
20G.HG.03 G.HG.07 cb1_on_gp99.81720NoNoYesNo69
21G.HG.03 G.s5hg.01 cb1_on_gp98.12550NoNoYesNo69
22G.S5.07 G.s5hg.01 cb1_on_gp96.82190YesNoYesNo99
23G.H1.04 G.S5.07 cb1_on_gp14.05980NoNoYesNo79
24G.H1.04 G.S5.05 cb1_on_gp14.16610NoNoYesNo79
25G.S4.03 G.S5.05 cb1_on_gp30.02930YesNoYesNo79
26G.S1.04 G.S4.03 cb1_on_gp27.47540NoNoYesNo77
27G.S1.04 G.S3.03 cb1_on_gp27.23880NoNoYesNo77
28G.S1.02 G.S3.03 cb1_on_gp11.57450YesNoYesNo57
29G.S4.04 G.S5.04 cb1_on_gp68.82840YesNoYesNo99
30G.H4.15 G.S5.04 cb1_on_gp34.29240YesNoYesNo89
31G.S5.04 G.S5.06 cb1_on_gp34.16650YesNoNoNo98
32G.S5.06 G.S6.05 cb1_on_gp34.11760NoNoYesNo84
33G.HG.01 G.S6.05 cb1_on_gp33.59540YesNoYesNo54
34G.HG.01 G.HG.04 cb1_on_gp33.53490YesNoYesNo59
35G.HG.04 G.s4h3.04 cb1_on_gp33.47820YesNoYesNo98
36G.S5.07 G.s6h5.01 cb1_on_gp80.78270YesNoYesNo99
37G.S5.05 G.s6h5.01 cb1_on_gp13.93930YesNoYesNo99
38G.S3.01 G.S3.03 cb1_on_gp11.29830YesNoYesNo47
39G.S1.03 G.S3.06 cb1_on_gp24.47060NoNoYesNo95
40G.S3.06 G.h2s4.01 cb1_on_gp25.70480YesNoYesNo59
41G.S1.05 G.h2s4.01 cb1_on_gp13.13650NoNoYesNo99
42G.S1.05 G.S1.07 cb1_on_gp13.12710NoNoNoNo99
43G.H3.12 G.S1.07 cb1_on_gp13.49870NoNoNoNo89
44G.S1.02 I2x51 cb1_on_gp11.02590YesNoNoNo57
45G.S3.01 I2x51 cb1_on_gp11.03640YesNoNoNo47
46G.H2.06 b.l9x6 cb1_on_gp66.07480YesNoYesNo98
47G.H2.06 b.l19x1 cb1_on_gp65.96690YesNoYesNo99
48G.S6.04 G.s6h5.01 cb1_on_gp65.93140YesNoYesNo99
49G.H5.10 G.S6.04 cb1_on_gp67.31180NoNoYesNo69
50G.H5.10 G.S6.02 cb1_on_gp68.96330NoNoYesNo67
51G.H5.13 G.S6.02 cb1_on_gp67.21480YesNoYesNo87
52G.H5.13 G.H5.17 cb1_on_gp65.2070YesNoNoNo85
53G.H5.15 I2x51 cb1_on_gp21.51180NoNoNoNo77
546x29 G.H5.17 cb1_on_gp65.08830NoNoNoNo65
55G.H5.15 G.H5.19 cb1_on_gp20.41050NoNoNoNo78
56G.H5.19 I2x53 cb1_on_gp19.85980NoNoYesYes87
572x37 G.H5.22 cb1_on_gp11.04160YesYesNoNo54
58G.H5.22 I2x53 cb1_on_gp11.59310NoNoYesYes47
593x50 G.H5.25 cb1_on_gp63.55290YesYesNoNo97
606x32 G.H5.25 cb1_on_gp63.67210YesNoNoNo77
616x32 G.H5.26 cb1_on_gp64.14320YesNoNoNo75
626x29 G.H5.26 cb1_on_gp64.26220NoNoNoNo65
63b.l17x5 b.l19x1 cb1_on_gp66.21840NoNoYesNo69
64b.b19x6 b.l17x5 cb1_on_gp26.76360NoNoNoNo96
65b.b19x6 b.l17x3 cb1_on_gp26.69890NoNoYesNo99
66b.b19x4 b.l17x3 cb1_on_gp28.11870YesNoYesNo89
67b.b19x4 b.b20x6 cb1_on_gp24.09470YesNoYesNo86
68b.b17x7 b.b20x6 cb1_on_gp54.42080YesNoYesNo86
69b.b17x7 b.b21x1 cb1_on_gp49.46710YesNoYesNo87
70b.1x19 b.b21x1 cb1_on_gp47.27730NoNoYesNo67
71b.1x15 b.1x19 cb1_on_gp12.10510NoNoNoNo76
72b.1x15 g.h1x11 cb1_on_gp11.71350NoNoYesNo79
73b.l17x5 b.l19x2 cb1_on_gp39.40830NoNoYesNo69
74b.l17x3 b.l19x2 cb1_on_gp26.7130YesNoYesNo99
75b.b20x4 b.l17x3 cb1_on_gp24.6980YesNoYesNo89
76b.b20x4 b.b20x6 cb1_on_gp36.13610YesNoYesNo86
77b.b20x2 b.l19x2 cb1_on_gp12.57980YesNoYesNo69
78b.b20x2 b.b20x4 cb1_on_gp12.35980YesNoYesNo68
79b.1x19 b.b21x2 cb1_on_gp35.12160NoNoNoNo66
80b.b3x2 b.b4x6 cb1_on_gp15.72850NoNoYesNo59
81b.b2x5 b.b3x2 cb1_on_gp15.58380YesNoNoNo75
82b.b2x5 b.l26x1 cb1_on_gp15.38340YesNoNoNo77
83b.l26x1 b.l26x3 cb1_on_gp15.08960NoNoNoNo77
84b.l26x3 b.l26x5 cb1_on_gp14.95350NoNoNoNo75
85b.l26x5 g.ctx4 cb1_on_gp14.81310NoNoNoNo57
86g.ctx3 g.ctx4 cb1_on_gp14.130YesNoNoNo97
87g.ctx3 g.ctx6 cb1_on_gp11.99440YesNoYesNo96
88b.l22x5 g.ctx6 cb1_on_gp10.74780YesNoYesNo96
89b.b22x5 b.b23x2 cb1_on_gp10.58180YesNoYesNo76
90b.l18x1 b.l18x3 cb1_on_gp29.4990YesNoYesNo65
91b.l18x3 b.l18x5 cb1_on_gp32.47130YesNoNoNo52
92b.l18x5 b.l20x2 cb1_on_gp32.84540NoNoNoNo29
93b.b21x2 g.l1x5 cb1_on_gp33.97670NoNoNoNo64
94b.b21x7 b.b24x6 cb1_on_gp12.49140YesNoNoNo58
952x64 Lig cb1_on_gp22.12230YesNoYesYes40
963x36 Lig cb1_on_gp25.62960YesYesYesYes70
973x36 3x39 cb1_on_gp26.93360YesYesNoNo79
982x50 3x39 cb1_on_gp27.19510YesNoNoNo99
992x46 2x50 cb1_on_gp17.68710YesYesYesNo99
1002x46 3x43 cb1_on_gp19.34480YesYesNoNo98
1013x43 7x53 cb1_on_gp60.54250NoNoYesYes89
1023x50 7x53 cb1_on_gp61.22750YesYesYesYes99
1032x50 7x49 cb1_on_gp17.654.8302YesNoYesYes99
1043x43 7x49 cb1_on_gp41.0770NoNoYesYes89
1055x43 Lig cb1_on_gp12.80460YesYesYesYes60
1065x43 6x48 cb1_on_gp17.6890YesYesYesYes68
1072x64 E1.D184 cb1_on_gp10.87850YesNoNoNo42
108G.H3.12 G.S4.04 cb1_on_gp13.55880NoNoYesNo89
109G.H2.07 G.h2s4.01 cb1_on_gp14.4140YesNoYesNo99
110b.l20x2 g.l1x5 cb1_on_gp33.59820NoNoNoNo94
111b.b22x5 b.l18x1 cb1_on_gp21.85060YesNoYesNo76
1126x48 7x45 Shared22.849779.0193YesYesNoYes89
1137x45 7x49 Shared23.366100NoYesYesYes99
114Lig NT.F102 cb1_off026.2594YesYesNoYes00
1153x25 NT.F102 cb1_off016.1474NoYesNoYes90
1163x28 NT.F102 cb1_off012.8612NoYesNoYes60
117Lig NT.I105 cb1_off015.7355YesYesNoNo00
118NT.E106 NT.I105 cb1_off014.9788NoNoNoNo40
1196x51 7x34 cb1_off2.8028914.4845YesYesYesYes74
120NT.E106 NT.L111 cb1_off014.039NoNoNoYes44
1211x31 NT.L111 cb1_off011.5369NoNoNoYes24
1221x28 1x31 cb1_off0.81032710.5819NoYesNoNo62
1231x46 1x49 cb1_off010.3225YesYesNoYes78
1241x46 7x42 cb1_off013.8498YesYesNoNo77
1252x57 7x42 cb1_off0.46726213.923YesYesNoNo77
1262x57 Lig cb1_off0.8616211.7261YesYesYesYes70
1271x49 7x50 cb1_off2.4403614.5547NoYesNoNo89
1286x48 7x41 cb1_off074.6041YesYesNoNo87
1297x41 Lig cb1_off058.9601NoNoYesYes70
1301x53 7x50 cb1_off013.3158NoNoNoNo99
1311x53 7x53 cb1_off014.2617NoNoYesYes99
1327x49 7x53 cb1_off097.8366YesYesYesYes99
1332x45 4x50 cb1_off0.69817514.0604NoNoYesYes99
1342x45 3x42 cb1_off1.5342930.9981NoNoNoNo98
1352x46 3x42 cb1_off1.6734632.1667YesYesNoNo98
1362x46 7x53 cb1_off044.0485YesYesYesYes99
1371x57 2x44 cb1_off067.0369NoNoNoNo76
1382x43 2x44 cb1_off067.8241NoNoNoNo86
1392x43 7x53 cb1_off074.7719NoNoYesYes89
1401x57 I1x50 cb1_off066.4205NoNoNoNo79
1411x56 8x50 cb1_off2.2099710.289NoYesYesNo88
1428x47 8x50 cb1_off0.00033969411.421NoNoYesNo88
1432x40 8x47 cb1_off0.55236812.4859YesYesNoNo98
1442x40 I1x50 cb1_off3.8656464.0863YesYesNoNo99
1452x41 4x46 cb1_off012.9283NoNoNoNo38
1462x45 4x46 cb1_off0.69817516.358NoNoNoNo98
1472x39 2x40 cb1_off048.7535NoNoYesYes89
1483x49 I2x57 cb1_off019.9066NoYesNoYes96
1492x39 3x49 cb1_off0.55255148.6773NoNoNoYes89
1502x42 2x43 cb1_off029.3839NoYesNoNo88
1512x42 2x46 cb1_off026.2106NoYesYesYes89
1522x42 6x37 cb1_off040.1733NoYesNoNo88
1533x29 E2.F268 cb1_off0.00039195410.4019NoNoYesYes45
154E2.F268 Lig cb1_off0.46956115.5707YesYesYesYes50
1553x36 5x43 cb1_off037.7109YesYesYesYes76
1563x36 6x48 cb1_off036.646YesYesYesYes78
1573x36 3x40 cb1_off012.4584YesYesNoNo77
1585x58 6x37 cb1_off0.57808138.8094YesYesNoNo98
1593x49 I2x53 cb1_off3.3146520.9227NoYesYesYes97
1603x51 3x55 cb1_off7.83909e-0519.095NoNoNoNo86
1613x55 3x56 cb1_off0.14442221.2584NoNoNoYes65
1623x56 I2x56 cb1_off029.8508NoYesNoNo54
1633x52 I2x56 cb1_off2.7623431.9836NoNoNoNo54
1643x52 I2x53 cb1_off017.2917NoNoYesYes57
1653x52 I2x57 cb1_off3.3146516.8157NoNoNoYes56
1663x51 5x60 cb1_off0.28871416.9255NoNoYesNo84
1675x39 E2.W255 cb1_off1.255818.6068YesNoYesYes75
1685x39 5x43 cb1_off3.2054321.6642YesNoYesYes76
1695x60 5x64 cb1_off1.0100112.5683YesNoNoYes45
1705x66 6x31 cb1_off015.5616NoNoNoYes55
1715x62 5x66 cb1_off018.5458NoNoNoNo65
1725x62 6x38 cb1_off022.0547NoNoNoNo66
1735x58 6x38 cb1_off027.2755YesYesNoNo96
1746x51 7x41 cb1_off0.1362715.4212YesYesNoNo77
1756x44 7x45 cb1_off021.0966NoNoNoYes99
1763x36 6x44 cb1_off020.6511YesYesNoNo79

Here, those paths that begin and end at given residue pair(s) or that pass through a residue are used to generate a novel metapath. Such a path filtering is particularly recommended if some information on allosteric residues is available. The selection syntax for a residue pair ("Pairs") is C:C:c534,A:A:?600 (the lower-case "c" stands for cytosine and "?" indicates any non standard amino acid or nucleotide residue). Selection of more than one apical residue pair has the following syntax: C:C:c534,A:A:?600,C:C:c534,A:A:E41. Only one residue can be selected as a tail ("Tail"). For midway residue(s), each residue must be separated by a comma as well e.g. A:A:?600,A:A:E41.

Midway



Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.


2D representation of the interactions of this orthosteric/allosteric ligand.


Node1Node2OwnerNet1LinkStrengthNet2LinkStrengthComm1Comm2Node1ShellNode2Shell
LigNT.F102cb1_off4.5901301
LigNT.M103cb1_off11.9701301
LigNT.I105cb1_off11.0801301
1x39Ligcb1_off4.2201010
2x57LigShared12.67510.1151310
3x32LigShared16.3255.4550010
E2.F268LigShared7.313.21310
6x51Ligcb1_off4.81501310
7x38LigShared17.4153.030310
7x39Ligcb1_off8.8100310
7x41Ligcb1_off4.96501010
2x64NT.N101cb1_off13.2900312
E1.D184NT.N101cb1_off7.40500022
NT.F102NT.M103cb1_off4.97501011
2x60NT.F102cb1_off5.2801011
3x25NT.F102cb1_off6.965011021
3x28NT.F102cb1_off9.3101021
2x57NT.M103cb1_off6.8401311
2x60NT.M103cb1_off6.13501011
2x61NT.M103cb1_off3.73500311
2x64NT.D104cb1_off9.55500312
NT.E106NT.I105cb1_off4.100021
NT.E106NT.L111cb1_off5.300022
7x34NT.F108cb1_off5.3600312
1x392x57cb1_off3.96501011
1x392x61cb1_off4.62501011
1x402x61cb1_off6.0900021
2x577x42Shared11.574.2651312
2x603x28Shared7.654.591012
2x612x65Shared16.47.920311
2x642x65Shared10.757.350311
3x28E1.D184cb1_off9.6801022
3x29E2.F268Shared7.924.2650311
3x29E2.I271Shared3.5653.570311
3x335x43Shared10.9156.0650311
3x363x40cb1_off6.55501012
3x365x43cb1_off5.51501011
3x365x47cb1_off6.50501012
3x366x44cb1_off4.8701012
3x366x48cb1_off29.56501012
3x366x52cb1_off4.2601012
3x375x43Shared6.0658.490021
4x605x39Shared19.479.040021
5x39E2.W255Shared13.98513.020312
5x42E2.W255cb1_off4.0100322
E2.I271E2.S265Shared4.6451.550312
E2.F268E2.I267Shared10.059.421312
6x55E2.I267cb1_off3.64501312
7x34E2.I267Shared9.428.160312
6x55E2.F268cb1_off4.97501311
5x40E2.I271Shared4.9953.570021
5x435x44cb1_off5.28501312
5x435x47Shared6.119.1951312
6x446x48cb1_off3.41501022
6x487x41cb1_off18.2801021
6x516x55Shared4.243.5351311
6x517x34Shared6.093.6551311
6x517x41Shared4.763.9651311
6x547x34Shared6.917.5350021
4x565x42Shared3.148.160322
1x432x57cb1_off3.0100021
1x362x61cb1_off2.7700021
3x303x33Shared2.732.730021
5x395x43Shared2.413.8550311
2x563x32Shared2.3053.070021
1x35NT.L111cb1_off2.1400322
2x53Ligcb1_off2.12500010
7x35NT.F108cb1_off2.0800022
2x572x58cb1_off1.96501312
3x304x57cb1_off1.9500022
2x533x35Shared1.8553.710012
1x381x39Shared1.51.50021
2x64NT.F108cb1_on_gp04.8250312
E1.H181NT.M109cb1_on_gp03.280322
2x65NT.L111cb1_on_gp03.2150312
1x352x61cb1_on_gp03.770321
1x357x39cb1_on_gp03.6450321
2x572x61cb1_on_gp010.7151311
2x577x38cb1_on_gp04.621311
2x60Ligcb1_on_gp04.721010
2x617x38cb1_on_gp05.9450311
2x617x39cb1_on_gp03.110311
2x61Ligcb1_on_gp03.090310
2x64E1.H181cb1_on_gp05.090312
2x64Ligcb1_on_gp014.1150310
2x65Ligcb1_on_gp06.4550310
3x29Ligcb1_on_gp06.3650310
3x33Ligcb1_on_gp09.20310
3x353x36cb1_on_gp04.620021
3x363x39cb1_on_gp03.3051012
3x367x41cb1_on_gp09.081011
3x36Ligcb1_on_gp05.3751010
3x406x48cb1_on_gp06.130022
4x565x39cb1_on_gp03.0250321
E2.F268E2.I271cb1_on_gp07.5351311
5x39E2.I271cb1_on_gp06.650311
E2.I271Ligcb1_on_gp03.4150310
5x395x42cb1_on_gp03.610312
5x39Ligcb1_on_gp05.060310
5x436x48cb1_on_gp03.281312
5x43Ligcb1_on_gp015.341310
5x446x52cb1_on_gp04.280022
5x446x55cb1_on_gp07.290021
5x476x52cb1_on_gp03.7251022
6x486x51cb1_on_gp04.5551021
6x486x52cb1_on_gp03.9851022
6x557x34cb1_on_gp03.7351311
7x34Ligcb1_on_gp03.20310
NT.E106NT.M109cb1_on_gp04.060022
2x64NT.M109cb1_on_gp03.110312
1x392x62cb1_on_gp03.0951012
2x64E1.D184cb1_on_gp03.5850312
3x25E1.D184cb1_on_gp05.37511022
6x55Ligcb1_on_gp03.1851310
7x347x37cb1_on_gp02.7950312
1x392x58cb1_on_gp02.4251012
3x334x57cb1_on_gp01.680312
1x362x62cb1_on_gp01.6250022
1x391x40cb1_on_gp01.51012
2x657x35cb1_on_gp01.4650312

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Difference Members
Id Description
cb1_on_gp 6KPG-CB1-AM841-Gi1/β1/γ2
8K8J-CB1-Fenofibrate-chim(Gs-CtGq)/β1/γ2
cb1_off 5U09-CB1-Taranabant
5TGZ-CB1-AM6538
Network Difference
Value cb1_on_gp cb1_off
Imin 3.025 3.4
Number of Linked Nodes 915 284
Number of Specific Nodes 645 (70.49%) 14  (4.93%)
Number of Shared Nodes 270 (29.51%) 270  (95.07%)
Number of Links 1120 315
Number of Specific Links 984 (87.86%) 179  (56.83%)
Number of Shared Links 136 (12.14%) 136  (43.17%)
Number of Hubs 191 46
Number of Specific Hubs 169 (88.48%) 24  (52.17%)
Number of Shared Hubs 22 (11.52%) 22  (47.83%)
Average % Shared Neighbours (Jaccard) 9.95
Average % Shared Neighbours (Otsuka) 12.67
Average % Shared Neighbours (Overlap Coefficient) 15.32
Average % Shared Cliques (k3-6) 50.31
Graphlets Similarity 0.716879
Paths Difference
Value cb1_on_gp cb1_off
Number Of Nodes in MetaPath 105 62
Specific Nodes in MetaPath 96 (91.43%) 53  (85.48%)
Shared Nodes in MetaPath 270 (29.51%) 270  (29.51%)
Number Of Links MetaPath 113 65
Specific Links in MetaPath 111 (98.23%) 63  (96.92%)
Shared Links in MetaPath 136 (12.14%) 136  (12.14%)
Number of Shortest Paths 4681335 63052
Length Of Smallest Path 3 3
Average Path Length 41.3461 14.1993
Length of Longest Path 77 32
Minimum Path Strength 0.7025 0.7525
Average Path Strength 6.05756 6.61941
Maximum Path Strength 21.48 23.9225
Minimum Path Correlation 0.7 0.7
Average Path Correlation 0.991345 0.918106
Maximum Path Correlation 1 0.99
Minimum % Of Corr. Nodes 1.72414 3.33333
Average % Of Corr. Nodes 31.1164 40.876
Maximum % Of Corr. Nodes 100 100
Minimum Path Hubs % 0 0
Average Path Hubs % 58.9543 47.9436
Maximum Path Hubs % 100 100

Details about the values in these tables can be found in the corresponding documentation page .

You can download a compressed (zip) file with structure(s), 3D outputs (as PyMol and VMD scripts) and numerical data files (as csv and plain text files).

Download cb1_off_on_gp.zip<



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