psnGPCR

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Orange: nodes, hubs and links specific of cb1_off_allo network

Green: nodes, hubs and links shared by both networks

Purple: nodes, hubs and links specific of cb1_off network

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Owner: the name of the network the link belong to or "Shared" if the corresponding link is present in both networks.

Strength: the interaction strength between the two nodes or 0 if the link is not present.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Owner	cb1_off_allo Int. Strength	cb1_off Int. Strength	cb1_off_allo Hub1?	cb1_off Hub1?	cb1_off_allo Hub2?	cb1_off Hub2?	ConSurf1	ConSurf2
1	3x22	NT.N101	cb1_off_allo	3.62	0	No	No	No	Yes	3	6
2	NT.C107	NT.M103	cb1_off_allo	4.86	0	No	No	No	Yes	2	4
3	2x64	NT.I105	cb1_off_allo	5.02	0	Yes	No	No	No	4	3
4	NT.E106	NT.M109	cb1_off_allo	5.41	0	No	No	No	Yes	4	3
5	E2.P269	NT.F108	cb1_off_allo	7.22	0	No	No	No	Yes	3	5
6	2x64	NT.M109	cb1_off_allo	4.98	0	Yes	No	No	Yes	4	3
7	E1.H181	NT.M109	cb1_off_allo	9.19	0	No	No	No	Yes	3	3
8	7x32	NT.V110	cb1_off_allo	6.35	0	No	No	No	No	1	3
9	1x35	NT.L111	cb1_off_allo	4.28	0	Yes	No	No	No	5	4
10	2x65	NT.L111	cb1_off_allo	7.71	0	Yes	No	No	No	4	4
11	1x29	1x32	cb1_off_allo	4.74	0	No	No	No	No	2	4
12	1x31	7x36	cb1_off_allo	9.37	0	No	No	No	No	2	4
13	1x32	2x66	cb1_off_allo	7.16	0	No	No	No	No	4	4
14	1x35	2x61	cb1_off_allo	5.02	0	Yes	No	Yes	Yes	5	5
15	1x35	7x36	cb1_off_allo	7.54	0	Yes	No	No	No	5	4
16	1x35	7x39	cb1_off_allo	4.37	0	Yes	No	No	No	5	5
17	1x38	7x39	cb1_off_allo	5.65	0	No	No	No	No	5	5
18	1x39	2x62	cb1_off_allo	6.19	0	No	Yes	No	No	7	5
19	1x39	7x39	cb1_off_allo	4.6	0	No	Yes	No	No	7	5
20	1x42	7x43	cb1_off_allo	4.15	0	No	No	No	No	6	5
21	1x43	7x42	cb1_off_allo	3.42	0	No	No	No	No	6	7
22	1x46	1x50	cb1_off_allo	4.39	0	Yes	Yes	Yes	No	7	9
23	1x46	7x46	cb1_off_allo	6.4	0	Yes	Yes	No	No	7	9
24	1x50	2x51	cb1_off_allo	4.12	0	Yes	No	No	No	9	7
25	1x58	1x59	cb1_off_allo	5.14	0	No	No	No	No	4	5
26	8x50	I1x50	cb1_off_allo	4.15	0	No	No	Yes	No	8	9
27	2x39	I2x53	cb1_off_allo	5.09	0	No	No	Yes	Yes	8	7
28	2x40	2x43	cb1_off_allo	4.84	0	Yes	Yes	Yes	No	9	8
29	2x40	6x33	cb1_off_allo	5.86	0	Yes	Yes	No	No	9	8
30	2x41	Alloh34	cb1_off_allo	16.19	0	No	No	Yes	No	3	0
31	2x44	Alloh34	cb1_off_allo	3.31	0	No	No	Yes	No	6	0
32	2x50	3x39	cb1_off_allo	9.68	0	Yes	No	No	No	9	9
33	2x57	2x61	cb1_off_allo	5.36	0	Yes	Yes	Yes	Yes	7	5
34	2x57	3x32	cb1_off_allo	5.24	0	Yes	Yes	No	No	7	7
35	2x57	7x38	cb1_off_allo	5.28	0	Yes	Yes	No	No	7	6
36	2x57	7x41	cb1_off_allo	8.38	0	Yes	Yes	No	No	7	7
37	2x58	7x42	cb1_off_allo	4.47	0	No	No	No	No	7	7
38	2x60	Lig	cb1_off_allo	6.39	0	No	No	Yes	Yes	4	0
39	2x61	Lig	cb1_off_allo	11.22	0	Yes	Yes	Yes	Yes	5	0
40	2x63	E1.F180	cb1_off_allo	4.78	0	No	No	No	No	3	4
41	2x64	Lig	cb1_off_allo	6.04	0	Yes	No	Yes	Yes	4	0
42	2x65	Lig	cb1_off_allo	3.65	0	Yes	No	Yes	Yes	4	0
43	E1.D184	E1.R182	cb1_off_allo	5.96	0	No	No	No	No	2	4
44	3x28	E1.R182	cb1_off_allo	3.71	0	No	Yes	No	No	6	4
45	3x23	4x61	cb1_off_allo	5.49	0	No	No	No	No	1	5
46	3x25	3x29	cb1_off_allo	7.31	0	No	Yes	No	No	9	4
47	3x25	Lig	cb1_off_allo	3.45	0	No	Yes	Yes	Yes	9	0
48	3x26	4x60	cb1_off_allo	3.28	0	No	No	No	No	5	6
49	3x26	E2.H270	cb1_off_allo	3.86	0	No	No	Yes	Yes	5	3
50	3x29	Lig	cb1_off_allo	6.87	0	No	No	Yes	Yes	4	0
51	3x33	Lig	cb1_off_allo	5.22	0	No	No	Yes	Yes	6	0
52	3x39	6x44	cb1_off_allo	5.64	0	No	No	No	No	9	9
53	3x39	7x45	cb1_off_allo	6.99	0	No	No	Yes	Yes	9	9
54	3x42	4x46	cb1_off_allo	3.96	0	No	No	Yes	No	8	8
55	3x43	6x40	cb1_off_allo	4.28	0	No	No	No	No	8	8
56	3x43	6x41	cb1_off_allo	4.15	0	No	No	Yes	No	8	8
57	3x44	5x54	cb1_off_allo	6.28	0	No	No	No	No	7	8
58	3x51	3x56	cb1_off_allo	6.17	0	No	No	No	Yes	8	5
59	3x51	5x61	cb1_off_allo	3.63	0	No	No	No	No	8	9
60	3x54	3x55	cb1_off_allo	7.95	0	No	No	No	No	9	6
61	3x55	5x64	cb1_off_allo	5.24	0	No	No	No	Yes	6	5
62	I2x51	I2x55	cb1_off_allo	6.07	0	No	No	No	No	7	4
63	I2x52	I2x56	cb1_off_allo	3.25	0	No	No	No	No	5	4
64	4x39	4x43	cb1_off_allo	3.92	0	Yes	No	No	No	1	1
65	4x46	4x49	cb1_off_allo	3.73	0	Yes	No	Yes	No	8	6
66	4x47	Alloh34	cb1_off_allo	9.22	0	No	No	Yes	No	4	0
67	4x50	Alloh34	cb1_off_allo	22.06	0	Yes	Yes	Yes	No	9	0
68	4x51	Alloh34	cb1_off_allo	8.57	0	No	No	Yes	No	4	0
69	4x54	Alloh34	cb1_off_allo	8.3	0	No	No	Yes	No	4	0
70	4x59	5x39	cb1_off_allo	3.52	0	Yes	No	Yes	No	5	7
71	4x59	5x42	cb1_off_allo	3.65	0	Yes	No	No	No	5	6
72	5x38	E2.W255	cb1_off_allo	6.06	0	No	No	Yes	Yes	5	5
73	E2.S262	E2.V263	cb1_off_allo	3.23	0	No	No	No	No	3	4
74	E2.F268	E2.S265	cb1_off_allo	3.96	0	Yes	Yes	No	No	5	4
75	5x37	E2.D266	cb1_off_allo	5.53	0	No	No	Yes	No	3	4
76	7x34	E2.F268	cb1_off_allo	4.29	0	Yes	Yes	Yes	Yes	4	5
77	5x39	E2.I271	cb1_off_allo	7.25	0	Yes	No	No	No	7	3
78	5x37	6x58	cb1_off_allo	4.15	0	No	No	Yes	Yes	3	4
79	5x40	5x44	cb1_off_allo	4.28	0	No	No	No	No	5	5
80	5x43	6x52	cb1_off_allo	3.42	0	Yes	Yes	No	No	6	7
81	5x43	Lig	cb1_off_allo	10.49	0	Yes	Yes	Yes	Yes	6	0
82	5x44	6x52	cb1_off_allo	5.71	0	No	No	No	No	5	7
83	5x54	6x41	cb1_off_allo	4.28	0	No	No	Yes	No	8	8
84	5x60	5x63	cb1_off_allo	3.86	0	No	No	No	No	4	3
85	6x28	6x31	cb1_off_allo	8.77	0	No	No	No	Yes	4	5
86	6x33	6x36	cb1_off_allo	4.42	0	No	No	No	No	8	8
87	6x48	Lig	cb1_off_allo	8.07	0	Yes	Yes	Yes	Yes	8	0
88	6x50	7x40	cb1_off_allo	3.28	0	No	No	No	No	9	7
89	6x55	Lig	cb1_off_allo	4.01	0	No	No	Yes	Yes	6	0
90	7x30	E3.M371	cb1_off_allo	5.83	0	No	Yes	Yes	No	3	1
91	7x34	Lig	cb1_off_allo	8.63	0	Yes	Yes	Yes	Yes	4	0
92	8x57	8x58	cb1_off_allo	3.73	0	No	No	No	No	5	5
93	6x43	7x48	cb1_off_allo	3.21	0	No	No	No	No	6	6
94	6x47	7x40	cb1_off_allo	3.17	0	No	No	No	No	8	7
95	1x54	2x47	cb1_off_allo	3.15	0	No	No	No	No	7	9
96	3x53	3x54	cb1_off_allo	3.1	0	Yes	No	No	No	8	9
97	7x31	NT.V110	cb1_off_allo	3.04	0	No	No	No	No	2	3
98	I1x49	I1x50	cb1_off_allo	3	0	No	No	Yes	No	5	9
99	2x54	7x42	cb1_off_allo	3	0	No	No	No	No	7	7
100	5x48	6x52	cb1_off_allo	3	0	No	No	No	No	5	7
101	4x58	4x61	cb1_off_allo	2.98	0	No	No	No	No	5	5
102	5x47	5x51	cb1_off_allo	2.98	0	No	No	No	No	8	6
103	4x48	4x51	cb1_off_allo	2.95	0	No	No	No	No	3	4
104	1x57	2x43	cb1_off_allo	2.94	0	No	No	Yes	No	7	8
105	3x48	3x52	cb1_off_allo	2.94	0	No	No	Yes	No	7	5
106	3x54	6x31	cb1_off_allo	2.94	0	No	No	No	Yes	9	5
107	2x46	6x40	cb1_off_allo	2.85	0	No	Yes	No	No	9	8
108	2x51	2x52	cb1_off_allo	2.77	0	No	No	No	No	7	6
109	3x50	6x34	cb1_off_allo	2.77	0	Yes	Yes	No	No	9	7
110	E2.D266	E3.M371	cb1_off_allo	2.77	0	Yes	No	Yes	No	4	1
111	6x25	6x29	cb1_off_allo	2.77	0	No	No	No	No	3	6
112	6x26	I2x54	cb1_off_allo	2.71	0	No	No	No	No	5	4
113	3x34	4x57	cb1_off_allo	1.79	0	No	No	No	No	5	7
114	2x49	3x35	cb1_off_allo	1.71	0	No	No	No	No	8	7
115	7x33	7x37	cb1_off_allo	1.71	0	No	No	No	No	4	5
116	1x35	7x35	cb1_off_allo	1.62	0	Yes	No	No	No	5	4
117	1x36	2x62	cb1_off_allo	1.62	0	No	No	No	No	5	5
118	5x46	5x47	cb1_off_allo	1.6	0	No	No	No	No	6	8
119	1x46	1x47	cb1_off_allo	1.59	0	Yes	Yes	No	No	7	6
120	6x51	7x37	cb1_off_allo	1.59	0	No	Yes	No	No	7	5
121	1x60	8x57	cb1_off_allo	1.53	0	No	No	No	No	6	5
122	5x55	5x59	cb1_off_allo	1.52	0	No	No	No	No	5	3
123	1x40	2x58	cb1_off_allo	1.49	0	No	No	No	No	3	7
124	E1.K183	NT.I105	cb1_off_allo	1.45	0	No	No	No	No	6	3
125	8x55	8x59	cb1_off_allo	1.44	0	No	No	No	No	5	4
126	8x58	8x59	cb1_off_allo	1.44	0	No	No	No	No	5	4
127	NT.D104	NT.M103	cb1_off_allo	1.39	0	No	No	No	Yes	6	4
128	NT.D104	NT.N101	cb1_off_allo	1.35	0	No	No	No	Yes	6	6
129	6x32	8x48	cb1_off_allo	1.35	0	No	No	No	No	7	5
130	1x45	7x47	cb1_off_allo	1.3	0	No	No	No	Yes	4	7
131	3x27	3x28	cb1_off_allo	1.24	0	No	No	No	Yes	5	6
132	6x57	E3.M371	cb1_off_allo	1.2	0	No	No	Yes	No	4	1
133	7x31	NT.F108	Shared	4.96	4.345	No	No	No	Yes	2	5
134	1x31	NT.L111	Shared	7.99	4.655	No	No	No	No	2	4
135	1x28	1x29	Shared	4.89	4.075	No	Yes	No	No	6	2
136	1x28	1x30	Shared	7.45	2.235	No	Yes	No	No	6	5
137	1x28	1x31	Shared	18.49	8.585	No	Yes	No	No	6	2
138	1x42	7x47	Shared	5.9	2.945	No	No	No	Yes	6	7
139	1x49	7x50	Shared	17.29	11.79	No	Yes	No	No	8	9
140	1x50	2x50	Shared	4.04	10.095	Yes	No	Yes	No	9	9
141	1x50	7x50	Shared	9.77	13.03	Yes	No	No	No	9	9
142	1x53	2x47	Shared	3.39	3.39	No	No	No	No	9	9
143	1x53	7x50	Shared	3.53	3.53	No	No	No	No	9	9
144	1x53	7x53	Shared	6.31	4.42	No	No	Yes	Yes	9	9
145	1x54	2x48	Shared	4.47	4.47	No	No	No	No	7	6
146	1x56	8x50	Shared	4.47	2.98	No	Yes	No	No	8	8
147	1x59	8x57	Shared	7.88	11.82	No	No	No	No	5	5
148	1x60	8x53	Shared	3.42	3.42	No	No	No	No	6	7
149	I1x48	I1x51	Shared	15.99	9.06	No	No	No	No	6	8
150	2x40	I1x50	Shared	7.03	9.965	Yes	Yes	Yes	No	9	9
151	I1.C149	I1x51	Shared	5.57	1.395	No	No	No	No	7	8
152	4x39	I1.C149	Shared	5.57	1.395	Yes	No	No	No	1	7
153	2x37	2x40	Shared	7.2	14.915	No	Yes	Yes	Yes	5	9
154	2x38	I2x57	Shared	3.53	3.53	No	No	Yes	Yes	5	6
155	2x39	3x49	Shared	4.42	2.21	No	No	Yes	Yes	8	9
156	2x40	8x49	Shared	11.49	5.75	Yes	Yes	No	No	9	6
157	2x41	4x39	Shared	6.77	2.82	No	No	Yes	No	3	1
158	2x41	4x46	Shared	16.97	7.35	No	No	Yes	No	3	8
159	2x42	2x43	Shared	10.05	7.535	No	Yes	Yes	No	8	8
160	2x42	3x46	Shared	4.16	4.855	No	Yes	No	No	8	9
161	2x42	6x37	Shared	9.74	8.525	No	Yes	No	No	8	8
162	2x43	7x53	Shared	7.25	5.44	Yes	No	Yes	Yes	8	9
163	2x45	3x42	Shared	4.89	5.705	No	No	No	No	9	8
164	2x45	4x46	Shared	9.25	5.28	No	No	Yes	No	9	8
165	2x45	4x50	Shared	6.18	6.18	No	No	Yes	Yes	9	9
166	2x46	7x53	Shared	5.86	6.445	No	Yes	Yes	Yes	9	9
167	2x50	7x46	Shared	11.78	8.83	Yes	No	No	No	9	9
168	2x50	7x49	Shared	6.73	8.08	Yes	No	No	Yes	9	9
169	2x53	3x35	Shared	3.71	1.855	No	No	No	No	8	7
170	2x57	Lig	Shared	12.09	12.285	Yes	Yes	Yes	Yes	7	0
171	2x59	2x63	Shared	4.6	6.895	No	No	No	No	7	3
172	2x61	2x65	Shared	14.71	16.4	Yes	Yes	Yes	No	5	4
173	2x63	E1.R182	Shared	21.44	11.32	No	No	No	No	3	4
174	2x64	2x65	Shared	9.05	10.75	Yes	No	Yes	No	4	4
175	2x66	E1.F180	Shared	3.93	3.93	No	No	No	No	4	4
176	3x24	E1.D184	Shared	5.84	4.38	No	No	No	No	5	2
177	3x28	E1.D184	Shared	9.68	9.68	No	Yes	No	No	6	2
178	3x21	3x24	Shared	6.46	4.04	No	No	No	No	7	5
179	3x22	E2.E258	Shared	5.82	8.72	No	No	Yes	Yes	3	1
180	3x22	E2.H270	Shared	5.64	6.205	No	No	Yes	Yes	3	3
181	3x25	E2.P269	Shared	11.56	9.39	No	Yes	No	No	9	3
182	3x33	5x43	Shared	4.85	10.915	No	No	Yes	Yes	6	6
183	3x36	3x40	Shared	5.24	6.555	Yes	Yes	No	No	7	7
184	3x36	5x43	Shared	4.01	5.515	Yes	Yes	Yes	Yes	7	6
185	3x36	5x47	Shared	3.93	6.505	Yes	Yes	No	No	7	8
186	3x36	6x48	Shared	36.08	29.565	Yes	Yes	Yes	Yes	7	8
187	3x37	4x53	Shared	3.36	3.36	No	No	No	No	6	8
188	3x37	5x43	Shared	4.85	6.065	No	No	Yes	Yes	6	6
189	3x38	4x50	Shared	7.78	9.08	No	No	Yes	Yes	7	9
190	3x40	5x50	Shared	4.47	3.725	No	No	No	No	7	8
191	3x41	4x49	Shared	3.49	5.24	No	No	Yes	No	5	6
192	3x45	4x46	Shared	12.18	10.35	No	No	Yes	No	6	8
193	3x45	4x49	Shared	7.07	5.655	No	No	Yes	No	6	6
194	3x46	6x37	Shared	4.73	3.94	No	No	No	No	9	8
195	3x47	5x58	Shared	8.01	5.34	No	No	No	Yes	8	9
196	3x49	3x50	Shared	9.53	10.125	Yes	Yes	Yes	Yes	9	9
197	3x49	I2x53	Shared	10.34	12.065	Yes	Yes	Yes	Yes	9	7
198	3x49	I2x57	Shared	4.38	4.38	Yes	Yes	Yes	Yes	9	6
199	3x50	3x53	Shared	10.54	10.54	Yes	Yes	Yes	No	9	8
200	3x50	6x30	Shared	3.57	7.745	Yes	Yes	No	No	9	7
201	3x50	6x33	Shared	13.36	9.715	Yes	Yes	No	No	9	8
202	3x51	3x55	Shared	8.71	14.16	No	No	No	No	8	6
203	3x52	I2x53	Shared	4.84	3.63	Yes	No	Yes	Yes	5	7
204	3x52	I2x56	Shared	4.42	5.89	Yes	No	No	No	5	4
205	3x52	I2x57	Shared	6.14	4.61	Yes	No	Yes	Yes	5	6
206	3x53	I2x53	Shared	8.9	5.09	Yes	No	Yes	Yes	8	7
207	3x53	6x30	Shared	7.36	6.625	Yes	No	No	No	8	7
208	I2x53	I2x57	Shared	7.57	6.94	Yes	Yes	Yes	Yes	7	6
209	4x38	4x40	Shared	6.99	6.12	No	No	No	No	8	4
210	4x38	4x41	Shared	4.5	4.5	No	No	No	No	8	5
211	4x49	4x50	Shared	5.82	5.235	Yes	No	Yes	Yes	6	9
212	4x59	E2.W255	Shared	4.56	6.26	Yes	No	Yes	Yes	5	5
213	4x60	5x39	Shared	16.69	19.47	No	No	Yes	No	6	7
214	5x36	E2.W255	Shared	7.82	8.375	No	Yes	Yes	Yes	5	5
215	5x39	E2.W255	Shared	8.68	13.985	Yes	No	Yes	Yes	7	5
216	5x42	E2.W255	Shared	13.03	4.01	No	No	Yes	Yes	6	5
217	E2.E258	E2.N256	Shared	3.94	4.6	Yes	Yes	No	No	1	6
218	E2.K259	E2.N256	Shared	5.6	5.595	No	No	No	No	4	6
219	E2.C257	E2.E258	Shared	4.56	5.32	No	No	Yes	Yes	9	1
220	E2.C257	E2.C264	Shared	7.28	7.28	No	No	No	No	9	9
221	E2.E258	E2.H270	Shared	11.08	12.31	Yes	Yes	Yes	Yes	1	3
222	5x36	E2.L260	Shared	5.43	2.715	No	Yes	No	No	5	3
223	5x36	E2.S262	Shared	5.89	5.885	No	Yes	No	No	5	3
224	6x58	E2.S265	Shared	5.89	3.68	Yes	Yes	No	No	4	4
225	6x58	E2.D266	Shared	3.99	5.985	Yes	Yes	Yes	No	4	4
226	E2.D266	E3.K370	Shared	4.15	4.15	Yes	No	No	No	4	1
227	E2.F268	E2.I267	Shared	17.58	10.05	Yes	Yes	No	Yes	5	4
228	6x58	E2.I267	Shared	7	4.9	Yes	Yes	No	Yes	4	4
229	7x34	E2.I267	Shared	11.3	9.42	Yes	Yes	No	Yes	4	4
230	6x55	E2.F268	Shared	6.22	4.975	No	No	Yes	Yes	6	5
231	E2.F268	Lig	Shared	21.58	7.07	Yes	Yes	Yes	Yes	5	0
232	E2.H270	E2.P269	Shared	4.58	4.58	Yes	Yes	No	No	3	3
233	5x40	6x59	Shared	4.47	2.98	No	No	No	Yes	5	4
234	5x41	6x59	Shared	6.09	4.565	No	No	No	Yes	4	4
235	5x55	6x41	Shared	4.47	3.725	No	No	Yes	No	5	8
236	5x58	6x37	Shared	12.89	11.725	No	Yes	No	No	9	8
237	5x58	6x38	Shared	3.79	2.525	No	Yes	No	No	9	6
238	5x60	5x64	Shared	5.97	15.525	No	No	No	Yes	4	5
239	5x63	5x64	Shared	4.64	4.64	No	No	No	Yes	3	5
240	5x65	6x31	Shared	3.25	2.435	No	No	No	Yes	8	5
241	6x26	6x30	Shared	7.83	7.18	No	No	No	No	5	7
242	6x35	7x56	Shared	3.71	2.475	No	No	No	No	7	7
243	6x36	7x56	Shared	14.23	11.64	No	No	No	No	8	7
244	6x39	7x52	Shared	4.28	4.995	No	No	No	No	7	9
245	6x40	7x52	Shared	5.89	3.68	No	No	No	No	8	9
246	6x41	6x45	Shared	4.28	4.28	Yes	No	No	No	8	6
247	6x44	7x45	Shared	4.12	3.43	No	No	Yes	Yes	9	9
248	6x47	7x45	Shared	9.45	7.875	No	No	Yes	Yes	8	9
249	6x48	7x41	Shared	6.53	18.28	Yes	Yes	No	No	8	7
250	6x48	7x45	Shared	3.39	6.215	Yes	Yes	Yes	Yes	8	9
251	6x49	6x50	Shared	4.06	4.06	No	No	No	No	5	9
252	6x51	7x34	Shared	4.87	6.09	No	Yes	Yes	Yes	7	4
253	6x54	7x34	Shared	5.02	6.91	No	No	Yes	Yes	4	4
254	6x59	6x60	Shared	3.93	2.62	No	Yes	No	No	4	5
255	7x27	7x30	Shared	9.91	6.375	No	No	No	Yes	1	3
256	7x38	Lig	Shared	9.58	16.605	No	No	Yes	Yes	6	0
257	7x45	7x49	Shared	8.17	8.175	Yes	Yes	No	Yes	9	9
258	7x49	7x53	Shared	4.65	8.14	No	Yes	Yes	Yes	9	9
259	8x54	8x58	Shared	7.5	1.07	No	No	No	No	7	5
260	1x46	2x54	Shared	3.2	5.6	Yes	Yes	No	No	7	7
261	3x45	4x45	Shared	3.15	3.15	No	No	No	No	6	5
262	1x46	7x47	Shared	3.14	7.85	Yes	Yes	No	Yes	7	7
263	2x56	3x32	Shared	3.07	2.305	No	No	No	No	5	7
264	6x42	6x46	Shared	3.07	3.07	No	No	No	No	6	5
265	1x60	I1x50	Shared	3	6.755	No	No	Yes	No	6	9
266	2x46	3x42	Shared	3	4.5	No	Yes	No	No	9	8
267	8x47	8x50	Shared	3	5.255	No	No	No	No	8	8
268	3x40	5x51	Shared	2.98	4.47	No	No	No	No	7	6
269	6x43	7x45	Shared	2.96	2.955	No	No	Yes	Yes	6	9
270	1x44	1x48	Shared	2.95	2.21	No	No	No	No	5	3
271	4x52	4x56	Shared	2.94	1.47	No	No	No	No	5	5
272	4x39	4x40	Shared	2.88	1.44	Yes	No	No	No	1	4
273	7x51	7x55	Shared	2.85	1.43	No	No	No	No	6	5
274	3x26	4x61	Shared	2.77	4.845	No	No	No	No	5	5
275	6x58	E3.M371	Shared	2.77	5.545	Yes	Yes	Yes	No	4	1
276	2x49	4x50	Shared	2.59	2.59	No	No	Yes	Yes	8	9
277	4x56	5x42	Shared	2.51	3.14	No	No	No	No	5	6
278	8x48	8x51	Shared	2.48	8.665	No	No	No	No	5	8
279	3x30	3x31	Shared	2.11	2.11	No	No	No	No	6	4
280	3x30	4x57	Shared	1.95	1.95	No	No	No	No	6	7
281	2x38	4x42	Shared	1.87	2.805	No	No	No	No	5	7
282	3x30	3x33	Shared	1.82	2.73	No	No	No	No	6	6
283	4x63	E2.K259	Shared	1.74	4.355	No	No	No	No	5	4
284	1x47	2x55	Shared	1.6	4.01	No	No	No	No	6	4
285	6x38	6x42	Shared	1.6	1.6	No	No	No	No	6	6
286	5x62	6x34	Shared	1.58	1.575	No	No	No	No	6	7
287	5x44	6x56	Shared	1.54	2.305	No	No	No	No	5	6
288	6x60	6x61	Shared	1.51	1.51	No	No	No	No	5	3
289	1x52	1x56	Shared	1.49	0.745	No	No	No	Yes	7	8
290	4x44	4x48	Shared	1.49	2.235	No	No	No	No	3	3
291	4x55	4x59	Shared	1.49	2.235	No	No	Yes	No	3	5
292	7x29	7x32	Shared	1.47	2.21	No	No	No	No	4	1
293	3x56	I2x50	Shared	1.44	1.44	No	Yes	No	No	5	8
294	1x51	2x51	Shared	1.38	3.46	No	No	No	No	3	7
295	8x48	8x49	Shared	1.38	0.69	No	No	No	No	5	6
296	1x49	7x51	Shared	1.37	2.73	No	Yes	No	No	8	6
297	5x56	5x60	Shared	0.99	1.985	No	No	No	No	4	4
298	E2.P269	NT.E100	cb1_off	0	7.075	No	No	No	No	3	0
299	E2.H270	NT.E100	cb1_off	0	11.08	Yes	Yes	No	No	3	0
300	2x64	NT.N101	cb1_off	0	13.29	Yes	No	No	Yes	4	6
301	E1.K183	NT.N101	cb1_off	0	6.295	No	No	No	Yes	6	6
302	E1.D184	NT.N101	cb1_off	0	7.405	No	No	No	Yes	2	6
303	NT.F102	NT.M103	cb1_off	0	4.975	No	Yes	No	Yes	5	4
304	2x60	NT.F102	cb1_off	0	5.28	No	No	No	Yes	4	5
305	3x25	NT.F102	cb1_off	0	6.965	No	Yes	No	Yes	9	5
306	3x28	NT.F102	cb1_off	0	9.31	No	Yes	No	Yes	6	5
307	Lig	NT.F102	cb1_off	0	4.39	Yes	Yes	No	Yes	0	5
308	2x57	NT.M103	cb1_off	0	6.84	Yes	Yes	No	Yes	7	4
309	2x60	NT.M103	cb1_off	0	6.135	No	No	No	Yes	4	4
310	2x61	NT.M103	cb1_off	0	3.735	Yes	Yes	No	Yes	5	4
311	Lig	NT.M103	cb1_off	0	11.44	Yes	Yes	No	Yes	0	4
312	2x64	NT.D104	cb1_off	0	9.555	Yes	No	No	No	4	6
313	NT.E106	NT.I105	cb1_off	0	4.1	No	No	No	No	4	3
314	Lig	NT.I105	cb1_off	0	10.315	Yes	Yes	No	No	0	3
315	1x28	NT.M109	cb1_off	0	8.415	No	Yes	No	Yes	6	3
316	1x32	NT.M109	cb1_off	0	3.4	No	No	No	Yes	4	3
317	1x28	1x32	cb1_off	0	3.96	No	Yes	No	No	6	4
318	1x31	1x35	cb1_off	0	3.43	No	No	Yes	No	2	5
319	1x39	2x57	cb1_off	0	3.965	No	Yes	Yes	Yes	7	7
320	1x39	2x61	cb1_off	0	4.625	No	Yes	Yes	Yes	7	5
321	1x39	Lig	cb1_off	0	3.975	No	Yes	Yes	Yes	7	0
322	1x40	2x61	cb1_off	0	6.09	No	No	Yes	Yes	3	5
323	1x45	1x49	cb1_off	0	12.245	No	No	No	Yes	4	8
324	1x46	1x49	cb1_off	0	3.525	Yes	Yes	No	Yes	7	8
325	1x46	7x42	cb1_off	0	3.685	Yes	Yes	No	No	7	7
326	1x47	2x54	cb1_off	0	4.85	No	No	No	No	6	7
327	1x49	7x47	cb1_off	0	4.23	No	Yes	No	Yes	8	7
328	2x37	2x39	cb1_off	0	4.61	No	Yes	No	No	5	8
329	2x37	8x49	cb1_off	0	5.36	No	Yes	No	No	5	6
330	2x39	2x40	cb1_off	0	5.09	No	No	Yes	Yes	8	9
331	2x40	8x47	cb1_off	0	3.815	Yes	Yes	No	No	9	8
332	2x41	4x43	cb1_off	0	4.15	No	No	No	No	3	1
333	2x42	2x46	cb1_off	0	4.87	No	Yes	No	Yes	8	9
334	2x48	4x50	cb1_off	0	4.29	No	No	Yes	Yes	6	9
335	2x57	7x42	cb1_off	0	11.57	Yes	Yes	No	No	7	7
336	2x59	3x28	cb1_off	0	4.18	No	No	No	Yes	7	6
337	2x60	3x28	cb1_off	0	7.65	No	No	No	Yes	4	6
338	2x62	2x66	cb1_off	0	3.84	No	No	No	No	5	4
339	2x63	3x28	cb1_off	0	4.15	No	No	No	Yes	3	6
340	3x22	3x23	cb1_off	0	6.63	No	No	No	No	3	1
341	3x25	3x26	cb1_off	0	4.26	No	Yes	No	No	9	5
342	3x25	E2.H270	cb1_off	0	8.485	No	Yes	Yes	Yes	9	3
343	3x26	E2.N256	cb1_off	0	4.805	No	No	No	No	5	6
344	3x29	E2.F268	cb1_off	0	7.92	No	No	Yes	Yes	4	5
345	3x29	E2.I271	cb1_off	0	3.565	No	No	No	No	4	3
346	3x32	Lig	cb1_off	0	15.525	No	No	Yes	Yes	7	0
347	3x36	6x44	cb1_off	0	4.87	Yes	Yes	No	No	7	9
348	3x36	6x52	cb1_off	0	4.26	Yes	Yes	No	No	7	7
349	3x43	5x58	cb1_off	0	4.685	No	No	No	Yes	8	9
350	3x44	3x48	cb1_off	0	5.655	No	No	No	No	7	7
351	3x44	5x50	cb1_off	0	6.09	No	No	No	No	7	8
352	3x50	I2x53	cb1_off	0	3.605	Yes	Yes	Yes	Yes	9	7
353	3x50	5x61	cb1_off	0	5.635	Yes	Yes	No	No	9	9
354	3x51	5x60	cb1_off	0	4.47	No	No	No	No	8	4
355	3x54	5x64	cb1_off	0	5.09	No	No	No	Yes	9	5
356	3x55	3x56	cb1_off	0	4.515	No	No	No	Yes	6	5
357	3x56	I2x52	cb1_off	0	4.84	No	Yes	No	No	5	5
358	3x56	I2x56	cb1_off	0	3.76	No	Yes	No	No	5	4
359	I2x52	I2x55	cb1_off	0	6.225	No	No	No	No	5	4
360	4x58	4x62	cb1_off	0	3.725	No	No	No	No	5	5
361	5x37	E2.V263	cb1_off	0	5.885	No	No	No	No	3	4
362	E2.I271	E2.S265	cb1_off	0	4.645	No	No	No	No	3	4
363	6x55	E2.I267	cb1_off	0	3.645	No	No	No	Yes	6	4
364	5x40	E2.I271	cb1_off	0	4.995	No	No	No	No	5	3
365	5x36	5x38	cb1_off	0	5.78	No	Yes	No	No	5	5
366	5x42	5x46	cb1_off	0	4.585	No	No	No	No	6	6
367	5x43	5x44	cb1_off	0	5.285	Yes	Yes	No	No	6	5
368	5x43	5x47	cb1_off	0	6.11	Yes	Yes	No	No	6	8
369	5x54	5x58	cb1_off	0	5.44	No	No	No	Yes	8	9
370	5x58	6x41	cb1_off	0	5.275	No	Yes	Yes	No	9	8
371	5x67	5x68	cb1_off	0	4.185	No	No	No	No	0	0
372	6x25	6x28	cb1_off	0	9.53	No	No	No	No	3	4
373	6x26	6x29	cb1_off	0	5.44	No	No	No	No	5	6
374	6x40	7x49	cb1_off	0	3.54	No	No	No	Yes	8	9
375	6x50	7x37	cb1_off	0	5.65	No	No	No	No	9	5
376	6x51	6x55	cb1_off	0	4.24	No	Yes	No	No	7	6
377	6x51	7x41	cb1_off	0	4.76	No	Yes	No	No	7	7
378	6x51	Lig	cb1_off	0	4.705	No	Yes	Yes	Yes	7	0
379	6x54	7x30	cb1_off	0	4.42	No	No	No	Yes	4	3
380	6x57	7x30	cb1_off	0	4.23	No	No	No	Yes	4	3
381	7x31	E3.M371	cb1_off	0	5.04	No	No	Yes	No	2	1
382	7x39	Lig	cb1_off	0	8.28	No	No	Yes	Yes	5	0
383	7x41	Lig	cb1_off	0	4.71	No	No	Yes	Yes	7	0
384	8x51	8x55	cb1_off	0	3.73	No	No	No	No	8	5
385	NT.E106	NT.L111	cb1_off	0	5.3	No	No	No	No	4	4
386	7x34	NT.F108	cb1_off	0	5.36	Yes	Yes	No	Yes	4	5
387	7x32	NT.M109	cb1_off	0	3.765	No	No	No	Yes	1	3
388	1x57	I1x50	cb1_off	0	3.57	No	No	Yes	No	7	9
389	1x60	I1x48	cb1_off	0	3.955	No	No	No	No	6	6
390	5x37	6x59	cb1_off	0	4.99	No	No	No	Yes	3	4
391	5x59	5x63	cb1_off	0	6.98	No	No	No	No	3	3
392	6x32	7x56	cb1_off	0	5.865	No	No	No	No	7	7
393	6x44	6x48	cb1_off	0	3.415	No	No	Yes	Yes	9	8
394	6x57	E3.K370	cb1_off	0	3.585	No	No	No	No	4	1
395	5x66	6x31	cb1_off	0	3.315	No	No	No	Yes	0	5
396	1x56	8x54	cb1_off	0	3.275	No	Yes	No	No	8	7
397	1x43	2x57	cb1_off	0	3.01	No	No	Yes	Yes	6	7
398	2x46	3x39	cb1_off	0	3	No	Yes	No	No	9	9
399	2x52	3x35	cb1_off	0	3	No	No	No	No	6	7
400	2x51	2x55	cb1_off	0	2.98	No	No	No	No	7	4
401	7x43	7x47	cb1_off	0	2.95	No	No	No	Yes	5	7
402	6x31	6x35	cb1_off	0	2.905	No	Yes	No	No	5	7
403	5x45	5x48	cb1_off	0	2.785	No	No	No	No	3	5
404	1x36	2x61	cb1_off	0	2.77	No	No	Yes	Yes	5	5
405	7x40	7x43	cb1_off	0	2.77	No	No	No	No	7	5
406	3x44	5x53	cb1_off	0	2.68	No	No	No	No	7	6
407	1x57	2x44	cb1_off	0	2.645	No	No	No	No	7	6
408	2x43	2x44	cb1_off	0	2.645	Yes	No	No	No	8	6
409	2x37	I1x49	cb1_off	0	2.635	No	Yes	No	No	5	5
410	5x62	5x66	cb1_off	0	2.57	No	No	No	No	6	0
411	NT.G99	NT.N101	cb1_off	0	2.545	No	No	No	Yes	0	6
412	5x39	5x43	cb1_off	0	2.41	Yes	No	Yes	Yes	7	6
413	7x47	7x48	cb1_off	0	2.38	No	Yes	No	No	7	6
414	7x30	7x33	cb1_off	0	2.305	No	Yes	No	No	3	4
415	5x62	6x38	cb1_off	0	2.235	No	No	No	No	6	6
416	NT.L111	NT.V110	cb1_off	0	2.235	No	No	No	No	4	3
417	E1.F180	E1.R182	cb1_off	0	2.14	No	No	No	No	4	4
418	8x52	8x56	cb1_off	0	2.09	No	No	No	No	4	3
419	5x53	5x57	cb1_off	0	2.08	No	No	No	No	6	7
420	7x35	NT.F108	cb1_off	0	2.08	No	No	No	Yes	4	5
421	5x66	5x70	cb1_off	0	2.075	No	No	No	No	0	0
422	2x53	Lig	cb1_off	0	1.99	No	No	Yes	Yes	8	0
423	5x49	5x53	cb1_off	0	1.965	No	No	No	No	6	6
424	2x57	2x58	cb1_off	0	1.965	Yes	Yes	No	No	7	7
425	3x31	3x34	cb1_off	0	1.95	No	No	No	No	4	5
426	7x36	NT.M109	cb1_off	0	1.865	No	No	No	Yes	4	3
427	7x28	NT.F108	cb1_off	0	1.86	No	No	No	Yes	3	5
428	5x44	5x45	cb1_off	0	1.76	No	No	No	No	5	3
429	4x50	4x54	cb1_off	0	1.76	Yes	Yes	No	No	9	4
430	4x43	4x47	cb1_off	0	1.71	No	No	No	No	1	4
431	6x49	6x52	cb1_off	0	1.71	No	No	No	No	5	7
432	4x54	4x58	cb1_off	0	1.54	No	No	No	No	4	5
433	1x38	1x39	cb1_off	0	1.5	No	No	No	Yes	5	7
434	NT.C107	NT.F108	cb1_off	0	1.395	No	No	No	Yes	2	5
435	1x54	1x58	cb1_off	0	1.385	No	No	No	No	7	4
436	3x27	4x61	cb1_off	0	1.22	No	No	No	No	5	5
437	I2x53	I2x54	cb1_off	0	1.195	Yes	Yes	No	No	7	4
438	6x24	6x27	cb1_off	0	0.935	No	No	No	No	0	4
439	5x69	6x27	cb1_off	0	0.895	No	No	No	No	0	4
440	1x55	8x57	cb1_off	0	0.81	No	No	No	No	4	5
441	6x27	6x31	cb1_off	0	0.81	No	No	No	Yes	4	5
442	1x37	1x41	cb1_off	0	0.795	No	No	No	No	4	4
443	1x44	2x58	cb1_off	0	0.795	No	No	No	No	5	7
444	5x64	5x67	cb1_off	0	0.765	No	Yes	No	No	5	0
445	4x51	4x52	cb1_off	0	0.76	No	No	No	No	4	5
446	1x56	8x57	cb1_off	0	0.76	No	Yes	No	No	8	5
447	1x33	1x37	cb1_off	0	0.745	No	No	No	No	5	4
448	I2x51	I2x54	cb1_off	0	0.705	No	No	No	No	7	4
449	1x59	8x56	cb1_off	0	0.695	No	No	No	No	5	3
450	E2.E258	E2.Q261	cb1_off	0	0.635	Yes	Yes	No	No	1	1

Orange: nodes, hubs and links specific of cb1_off_allo network

Green: nodes, hubs and links shared by both networks

Purple: nodes, hubs and links specific of cb1_off network

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Owner: the name of the network the hub belong to or "Shared" if the corresponding hub is present in both networks.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub in the corresponding network.

Num Of Links: the number of links of the corresponding hub in the corresponding network.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Owner	cb1_off_allo Avg Int. Strength	cb1_off Avg Int. Strength	cb1_off_allo Num Of Links	cb1_off Num Of Links	ConSurf
1	1x35	cb1_off_allo	4.566	3.43	5	1	5
2	1x50	cb1_off_allo	5.58	11.5625	4	2	9
3	I1x50	cb1_off_allo	4.295	6.76333	4	3	9
4	2x43	cb1_off_allo	6.27	5.20667	4	3	8
5	2x50	cb1_off_allo	8.0575	9.00167	4	3	9
6	2x64	cb1_off_allo	6.2725	11.1983	4	3	4
7	2x65	cb1_off_allo	8.78	13.575	4	2	4
8	3x52	cb1_off_allo	4.585	4.71	4	3	5
9	3x53	cb1_off_allo	7.475	7.41833	4	3	8
10	4x39	cb1_off_allo	4.785	1.885	4	3	1
11	4x46	cb1_off_allo	9.218	7.66	5	3	8
12	4x49	cb1_off_allo	5.0275	5.37667	4	3	6
13	4x59	cb1_off_allo	3.305	4.2475	4	2	5
14	E2.D266	cb1_off_allo	4.11	5.0675	4	2	4
15	5x39	cb1_off_allo	9.035	11.955	4	3	7
16	6x41	cb1_off_allo	4.295	4.42667	4	3	8
17	E3.M371	cb1_off_allo	3.1425	5.2925	4	2	1
18	Alloh34	cb1_off_allo	11.275	0	6	0	0
19	1x46	Shared	3.744	5.165	5	4	7
20	2x40	Shared	7.284	7.907	5	5	9
21	2x57	Shared	7.27	6.60583	5	6	7
22	2x61	Shared	9.0775	6.724	4	5	5
23	3x36	Shared	12.315	9.545	4	6	7
24	3x49	Shared	7.1675	7.195	4	4	9
25	3x50	Shared	7.954	7.89417	5	6	9
26	I2x53	Shared	7.348	5.42083	5	6	7
27	I2x57	Shared	5.405	4.865	4	4	6
28	4x50	Shared	8.886	4.85583	5	6	9
29	E2.W255	Shared	8.03	8.1575	5	4	5
30	E2.E258	Shared	6.35	6.317	4	5	1
31	E2.F268	Shared	10.726	7.50375	5	4	5
32	E2.H270	Shared	6.29	8.532	4	5	3
33	5x43	Shared	5.524	6.05	5	6	6
34	6x48	Shared	13.5175	14.3687	4	4	8
35	6x58	Shared	4.76	5.0275	5	4	4
36	7x34	Shared	6.822	6.945	5	4	4
37	7x45	Shared	5.84667	5.73	6	5	9
38	7x53	Shared	6.0175	6.11125	4	4	9
39	Lig	Shared	8.37786	8.44083	14	12	0
40	NT.N101	cb1_off	2.485	7.38375	2	4	6
41	NT.F102	cb1_off	0	6.184	0	5	5
42	NT.M103	cb1_off	3.125	6.625	2	5	4
43	NT.F108	cb1_off	6.09	3.008	2	5	5
44	NT.M109	cb1_off	6.52667	4.36125	3	4	3
45	1x28	cb1_off	10.2767	5.454	3	5	6
46	1x39	cb1_off	5.395	3.51625	2	4	7
47	1x49	cb1_off	9.33	6.904	2	5	8
48	1x56	cb1_off	2.98	1.94	2	4	8
49	2x37	cb1_off	7.2	6.88	1	4	5
50	2x42	cb1_off	7.98333	6.44625	3	4	8
51	2x46	cb1_off	3.90333	4.70375	3	4	9
52	3x25	cb1_off	7.44	7.275	3	4	9
53	3x28	cb1_off	4.87667	6.994	3	5	6
54	3x56	cb1_off	3.805	3.63875	2	4	5
55	E2.I267	cb1_off	11.96	7.00375	3	4	4
56	5x36	cb1_off	6.38	5.68875	3	4	5
57	5x58	cb1_off	8.23	5.83167	3	6	9
58	5x64	cb1_off	5.28333	6.505	3	4	5
59	6x31	cb1_off	4.98667	2.36625	3	4	5
60	6x51	cb1_off	3.23	4.94875	2	4	7
61	6x59	cb1_off	4.83	3.78875	3	4	4
62	7x30	cb1_off	7.87	4.3325	2	4	3
63	7x47	cb1_off	3.44667	4.071	3	5	7
64	7x49	cb1_off	6.51667	6.98375	3	4	9

Orange: nodes, hubs and links specific of cb1_off_allo network

Green: nodes, hubs and links shared by both networks

Purple: nodes, hubs and links specific of cb1_off network

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Owner: the name of the network the link belong to or "Shared" if the corresponding link is present in both networks.

Recurrence: the relative Recurrence in the filtered pool of shortest paths.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Owner	cb1_off_allo Recurrence	cb1_off Recurrence	cb1_off_allo Hub1?	cb1_off Hub1?	cb1_off_allo Hub2?	cb1_off Hub2?	ConSurf1	ConSurf2
1	3x25	Lig	cb1_off_allo	39.0832	0	No	Yes	Yes	Yes	9	0
2	3x25	E2.P269	cb1_off_allo	38.432	1.91588	No	Yes	No	No	9	3
3	E2.H270	E2.P269	cb1_off_allo	33.3873	0.0271542	Yes	Yes	No	No	3	3
4	1x31	NT.L111	cb1_off_allo	16.4395	9.45269	No	No	No	No	2	4
5	2x65	NT.L111	cb1_off_allo	17.059	0	Yes	No	No	No	4	4
6	2x65	Lig	cb1_off_allo	17.1702	0	Yes	No	Yes	Yes	4	0
7	1x28	1x31	cb1_off_allo	15.9281	7.54586	No	Yes	No	No	6	2
8	1x28	1x29	cb1_off_allo	13.7107	1.00169	No	Yes	No	No	6	2
9	1x29	1x32	cb1_off_allo	12.5925	0	No	No	No	No	2	4
10	1x32	2x66	cb1_off_allo	11.468	0	No	No	No	No	4	4
11	1x46	7x47	cb1_off_allo	13.1612	3.08955	Yes	Yes	No	Yes	7	7
12	1x46	1x50	cb1_off_allo	22.1449	0	Yes	Yes	Yes	No	7	9
13	1x50	2x50	cb1_off_allo	26.9227	2.77878	Yes	No	Yes	No	9	9
14	2x50	3x39	cb1_off_allo	18.0152	0	Yes	No	No	No	9	9
15	3x39	7x45	cb1_off_allo	18.2979	0	No	No	Yes	Yes	9	9
16	6x48	Lig	cb1_off_allo	87.4805	0	Yes	Yes	Yes	Yes	8	0
17	1x46	7x46	cb1_off_allo	17.113	0	Yes	Yes	No	No	7	9
18	2x50	7x46	cb1_off_allo	18.5076	1.17367	Yes	No	No	No	9	9
19	2x50	7x49	cb1_off_allo	29.4514	4.8244	Yes	No	No	Yes	9	9
20	2x54	7x42	cb1_off_allo	13.1612	0	No	No	No	No	7	7
21	1x46	2x54	cb1_off_allo	16.4364	5.80497	Yes	Yes	No	No	7	7
22	1x50	7x50	cb1_off_allo	10.7723	2.69129	Yes	No	No	No	9	9
23	2x40	2x43	cb1_off_allo	55.2877	0	Yes	Yes	Yes	No	9	8
24	3x42	4x46	cb1_off_allo	20.223	0	No	No	Yes	No	8	8
25	2x41	4x46	cb1_off_allo	15.5945	8.00748	No	No	Yes	No	3	8
26	3x49	3x50	cb1_off_allo	13.5741	6.91528	Yes	Yes	Yes	Yes	9	9
27	3x50	6x33	cb1_off_allo	37.0374	0.953415	Yes	Yes	No	No	9	8
28	2x40	6x33	cb1_off_allo	40.195	0	Yes	Yes	No	No	9	8
29	3x50	3x53	cb1_off_allo	18.39	1.02884	Yes	Yes	Yes	No	9	8
30	2x66	E1.F180	cb1_off_allo	10.3371	2.29604	No	No	No	No	4	4
31	3x26	E2.H270	cb1_off_allo	22.0782	0	No	No	Yes	Yes	5	3
32	3x26	4x60	cb1_off_allo	18.0755	0	No	No	No	No	5	6
33	5x43	Lig	cb1_off_allo	14.5049	0	Yes	Yes	Yes	Yes	6	0
34	2x46	6x40	cb1_off_allo	10.4705	0	No	Yes	No	No	9	8
35	3x53	3x54	cb1_off_allo	13.1707	0	Yes	No	No	No	8	9
36	4x60	5x39	cb1_off_allo	17.0558	1.58701	No	No	Yes	No	6	7
37	7x34	Lig	cb1_off_allo	13.9236	0	Yes	Yes	Yes	Yes	4	0
38	5x43	6x52	cb1_off_allo	15.6358	0	Yes	Yes	No	No	6	7
39	5x44	6x52	cb1_off_allo	12.205	0	No	No	No	No	5	7
40	6x58	E3.M371	cb1_off_allo	12.3606	2.4469	Yes	Yes	Yes	No	4	1
41	6x48	7x45	Shared	100	78.7443	Yes	Yes	Yes	Yes	8	9
42	7x45	7x49	Shared	83.4112	100	Yes	Yes	No	Yes	9	9
43	1x53	7x50	Shared	10.048	13.1909	No	No	No	No	9	9
44	1x53	7x53	Shared	13.2755	14.1474	No	No	Yes	Yes	9	9
45	7x49	7x53	Shared	77.8201	97.7884	No	Yes	Yes	Yes	9	9
46	2x40	I1x50	Shared	15.2483	61.5979	Yes	Yes	Yes	No	9	9
47	2x43	7x53	Shared	61.3965	73.2048	Yes	No	Yes	Yes	8	9
48	2x46	7x53	Shared	42.765	39.6603	No	Yes	Yes	Yes	9	9
49	2x46	3x42	Shared	33.7209	24.7405	No	Yes	No	No	9	8
50	2x45	3x42	Shared	12.6338	23.5789	No	No	No	No	9	8
51	2x45	4x50	Shared	11.7126	13.8909	No	No	Yes	Yes	9	9
52	3x36	5x43	Shared	10.7246	38.8064	Yes	Yes	Yes	Yes	7	6
53	3x36	6x48	Shared	15.1434	37.1862	Yes	Yes	Yes	Yes	7	8
54	E2.F268	Lig	Shared	19.1969	15.3482	Yes	Yes	Yes	Yes	5	0
55	6x58	E2.I267	Shared	16.4681	11.2931	Yes	Yes	No	Yes	4	4
56	3x28	NT.F102	cb1_off	0	12.6569	No	Yes	No	Yes	6	5
57	3x25	NT.F102	cb1_off	0	16.8477	No	Yes	No	Yes	9	5
58	2x57	Lig	cb1_off	3.52934	11.441	Yes	Yes	Yes	Yes	7	0
59	Lig	NT.F102	cb1_off	0	26.581	Yes	Yes	No	Yes	0	5
60	Lig	NT.I105	cb1_off	0	12.8711	Yes	Yes	No	No	0	3
61	NT.E106	NT.I105	cb1_off	0	12.1108	No	No	No	No	4	3
62	NT.E106	NT.L111	cb1_off	0	11.1725	No	No	No	No	4	4
63	1x46	1x49	cb1_off	0	10.1798	Yes	Yes	No	Yes	7	8
64	1x46	7x42	cb1_off	0	13.6344	Yes	Yes	No	No	7	7
65	2x57	7x42	cb1_off	0	13.7038	Yes	Yes	No	No	7	7
66	1x49	7x50	cb1_off	6.01989	14.4249	No	Yes	No	No	8	9
67	6x48	7x41	cb1_off	3.1386	74.2699	Yes	Yes	No	No	8	7
68	7x41	Lig	cb1_off	0	57.4674	No	No	Yes	Yes	7	0
69	8x47	8x50	cb1_off	1.07373	11.0246	No	No	No	No	8	8
70	2x40	8x47	cb1_off	0	12.0474	Yes	Yes	No	No	9	8
71	1x57	I1x50	cb1_off	0	62.2767	No	No	Yes	No	7	9
72	1x57	2x44	cb1_off	0	62.8047	No	No	No	No	7	6
73	2x43	2x44	cb1_off	0	63.5258	Yes	No	No	No	8	6
74	2x39	2x40	cb1_off	0	46.9255	No	No	Yes	Yes	8	9
75	3x49	I2x57	cb1_off	6.79818	19.1739	Yes	Yes	Yes	Yes	9	6
76	2x39	3x49	cb1_off	0.962546	46.8773	No	No	Yes	Yes	8	9
77	2x42	2x43	cb1_off	8.0784	26.587	No	Yes	Yes	No	8	8
78	2x42	2x46	cb1_off	0	23.1324	No	Yes	No	Yes	8	9
79	3x36	3x40	cb1_off	4.35528	12.3461	Yes	Yes	No	No	7	7
80	5x58	6x37	cb1_off	5.19076	38.6857	No	Yes	No	No	9	8
81	2x42	6x37	cb1_off	6.10248	40.0525	No	Yes	No	No	8	8
82	3x49	I2x53	cb1_off	4.8858	20.1515	Yes	Yes	Yes	Yes	9	7
83	3x51	3x55	cb1_off	4.16468	18.4045	No	No	No	No	8	6
84	3x55	3x56	cb1_off	0	20.4894	No	No	No	Yes	6	5
85	3x56	I2x56	cb1_off	0	28.7684	No	Yes	No	No	5	4
86	3x52	I2x56	cb1_off	5.95635	30.8231	Yes	No	No	No	5	4
87	3x52	I2x53	cb1_off	7.97675	16.6697	Yes	No	Yes	Yes	5	7
88	3x52	I2x57	cb1_off	3.91054	16.199	Yes	No	Yes	Yes	5	6
89	3x51	5x60	cb1_off	0	16.3137	No	No	No	No	8	4
90	5x60	5x64	cb1_off	2.08711	12.1138	No	No	No	Yes	4	5
91	5x39	E2.W255	cb1_off	9.59687	18.4377	Yes	No	Yes	Yes	7	5
92	5x39	5x43	cb1_off	0	21.4669	Yes	No	Yes	Yes	7	6
93	5x66	6x31	cb1_off	0	15.5081	No	No	No	Yes	0	5
94	5x62	5x66	cb1_off	0	18.4951	No	No	No	No	6	0
95	5x62	6x38	cb1_off	0	21.9889	No	No	No	No	6	6
96	5x58	6x38	cb1_off	3.20849	27.1874	No	Yes	No	No	9	6
97	6x51	7x34	cb1_off	3.11001	14.6573	No	Yes	Yes	Yes	7	4
98	6x44	7x45	cb1_off	0.908542	21.3885	No	No	Yes	Yes	9	9
99	3x36	6x44	cb1_off	0	20.951	Yes	Yes	No	No	7	9
100	6x51	7x41	cb1_off	0	16.5792	No	Yes	No	No	7	7

Here, those paths that begin and end at given residue pair(s) or that pass through a residue are used to generate a novel metapath. Such a path filtering is particularly recommended if some information on allosteric residues is available. The selection syntax for a residue pair ("Pairs") is C:C:c534,A:A:?600 (the lower-case "c" stands for cytosine and "?" indicates any non standard amino acid or nucleotide residue). Selection of more than one apical residue pair has the following syntax: C:C:c534,A:A:?600,C:C:c534,A:A:E41. Only one residue can be selected as a tail ("Tail"). For midway residue(s), each residue must be separated by a comma as well e.g. A:A:?600,A:A:E41.

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Node1	Node2	Owner	Net1LinkStrength	Net2LinkStrength	Comm1	Comm2	Node1Shell	Node2Shell
2x64	NT.N101	cb1_off	13.29	0	0	1	1	2
E1.K183	NT.N101	cb1_off	6.295	0	0	0	2	2
NT.F102	NT.M103	cb1_off	4.975	0	1	0	1	1
2x60	NT.F102	cb1_off	5.28	0	1	0	1	1
3x25	NT.F102	cb1_off	6.965	0	1	1	1	1
3x28	NT.F102	cb1_off	9.31	0	1	8	2	1
Lig	NT.F102	cb1_off	4.39	0	1	1	0	1
2x57	NT.M103	cb1_off	6.84	0	1	1	1	1
2x60	NT.M103	cb1_off	6.135	0	1	0	1	1
2x61	NT.M103	cb1_off	3.735	0	0	1	1	1
Lig	NT.M103	cb1_off	11.44	0	1	1	0	1
2x64	NT.D104	cb1_off	9.555	0	0	1	1	2
NT.E106	NT.I105	cb1_off	4.1	0	0	0	2	1
Lig	NT.I105	cb1_off	10.315	0	1	1	0	1
1x39	2x57	cb1_off	3.965	0	1	0	1	1
1x39	2x61	cb1_off	4.625	0	1	0	1	1
1x39	Lig	cb1_off	3.975	0	1	0	1	0
1x40	2x61	cb1_off	6.09	0	0	0	2	1
2x57	7x42	cb1_off	11.57	0	1	1	1	2
2x57	Lig	Shared	12.285	12.09	1	1	1	0
2x60	3x28	cb1_off	7.65	0	1	0	1	2
2x61	2x65	Shared	16.4	14.71	0	1	1	1
2x64	2x65	Shared	10.75	9.05	0	1	1	1
3x25	3x26	cb1_off	4.26	0	1	1	1	2
3x25	E2.P269	Shared	9.39	11.56	1	1	1	2
3x25	E2.H270	cb1_off	8.485	0	1	1	1	2
3x29	E2.F268	cb1_off	7.92	0	0	1	1	1
3x29	E2.I271	cb1_off	3.565	0	0	1	1	2
3x32	Lig	cb1_off	15.525	0	0	0	1	0
3x33	5x43	Shared	10.915	4.85	0	1	1	1
3x36	5x43	Shared	5.515	4.01	1	0	2	1
3x36	5x47	Shared	6.505	3.93	1	0	2	2
3x36	6x44	cb1_off	4.87	0	1	0	2	2
3x36	6x48	Shared	29.565	36.08	1	0	2	1
3x36	6x52	cb1_off	4.26	0	1	0	2	2
3x37	5x43	Shared	6.065	4.85	0	0	2	1
E2.I271	E2.S265	cb1_off	4.645	0	0	0	2	2
E2.F268	E2.I267	Shared	10.05	17.58	1	1	1	2
6x55	E2.I267	cb1_off	3.645	0	1	1	1	2
7x34	E2.I267	Shared	9.42	11.3	0	1	1	2
6x55	E2.F268	Shared	4.975	6.22	1	1	1	1
E2.F268	Lig	Shared	7.07	21.58	1	1	1	0
E2.H270	E2.P269	Shared	4.58	4.58	1	5	2	2
5x43	5x44	cb1_off	5.285	0	1	1	1	2
5x43	5x47	cb1_off	6.11	0	1	1	1	2
6x44	7x45	Shared	3.43	4.12	1	7	2	2
6x48	7x41	Shared	18.28	6.53	1	0	1	1
6x48	7x45	Shared	6.215	3.39	1	0	1	2
6x51	6x55	cb1_off	4.24	0	1	0	1	1
6x51	7x34	Shared	6.09	4.87	1	0	1	1
6x51	7x41	cb1_off	4.76	0	1	0	1	1
6x51	Lig	cb1_off	4.705	0	1	0	1	0
6x54	7x34	Shared	6.91	5.02	0	0	2	1
7x38	Lig	Shared	16.605	9.58	0	1	1	0
7x39	Lig	cb1_off	8.28	0	0	0	1	0
7x41	Lig	cb1_off	4.71	0	1	0	1	0
NT.E106	NT.L111	cb1_off	5.3	0	0	0	2	2
7x34	NT.F108	cb1_off	5.36	0	0	1	1	2
6x44	6x48	cb1_off	3.415	0	1	7	2	1
1x43	2x57	cb1_off	3.01	0	0	0	2	1
1x36	2x61	cb1_off	2.77	0	0	0	2	1
3x30	3x33	Shared	2.73	1.82	0	0	2	1
5x39	5x43	cb1_off	2.41	0	0	4	2	1
2x56	3x32	Shared	2.305	3.07	0	0	2	1
2x53	Lig	cb1_off	1.99	0	0	0	1	0
2x57	2x58	cb1_off	1.965	0	1	1	1	2
2x53	3x35	Shared	1.855	3.71	0	0	1	2
1x38	1x39	cb1_off	1.5	0	0	0	2	1
NT.C107	NT.F108	cb1_off	1.395	0	0	0	2	2
NT.C107	NT.M103	cb1_off_allo	0	4.86	0	0	2	1
2x64	NT.I105	cb1_off_allo	0	5.02	0	1	1	1
NT.E106	NT.M109	cb1_off_allo	0	5.41	0	0	2	2
E2.P269	NT.F108	cb1_off_allo	0	7.22	1	0	2	2
2x64	NT.M109	cb1_off_allo	0	4.98	0	1	1	2
1x35	NT.L111	cb1_off_allo	0	4.28	0	0	2	2
2x65	NT.L111	cb1_off_allo	0	7.71	0	1	1	2
1x35	2x61	cb1_off_allo	0	5.02	0	0	2	1
1x35	7x39	cb1_off_allo	0	4.37	0	0	2	1
1x38	7x39	cb1_off_allo	0	5.65	0	0	2	1
1x39	2x62	cb1_off_allo	0	6.19	1	0	1	2
1x39	7x39	cb1_off_allo	0	4.6	1	0	1	1
1x43	7x42	cb1_off_allo	0	3.42	0	0	2	2
2x57	2x61	cb1_off_allo	0	5.36	1	1	1	1
2x57	3x32	cb1_off_allo	0	5.24	1	1	1	1
2x57	7x38	cb1_off_allo	0	5.28	1	1	1	1
2x57	7x41	cb1_off_allo	0	8.38	1	1	1	1
2x58	7x42	cb1_off_allo	0	4.47	0	0	2	2
2x60	Lig	cb1_off_allo	0	6.39	1	0	1	0
2x61	Lig	cb1_off_allo	0	11.22	0	1	1	0
2x64	Lig	cb1_off_allo	0	6.04	0	1	1	0
2x65	Lig	cb1_off_allo	0	3.65	0	1	1	0
3x25	3x29	cb1_off_allo	0	7.31	1	1	1	1
3x25	Lig	cb1_off_allo	0	3.45	1	1	1	0
3x26	E2.H270	cb1_off_allo	0	3.86	0	0	2	2
3x29	Lig	cb1_off_allo	0	6.87	0	1	1	0
3x33	Lig	cb1_off_allo	0	5.22	0	1	1	0
E2.F268	E2.S265	cb1_off_allo	0	3.96	1	1	1	2
7x34	E2.F268	cb1_off_allo	0	4.29	0	1	1	1
5x39	E2.I271	cb1_off_allo	0	7.25	0	4	2	2
5x43	6x52	cb1_off_allo	0	3.42	1	1	1	2
5x43	Lig	cb1_off_allo	0	10.49	1	1	1	0
5x44	6x52	cb1_off_allo	0	5.71	0	0	2	2
6x48	Lig	cb1_off_allo	0	8.07	1	0	1	0
6x55	Lig	cb1_off_allo	0	4.01	1	1	1	0
7x34	Lig	cb1_off_allo	0	8.63	0	1	1	0
1x36	2x62	cb1_off_allo	0	1.62	0	0	2	2
6x51	7x37	cb1_off_allo	0	1.59	1	0	1	2
1x40	2x58	cb1_off_allo	0	1.49	0	0	2	2
E1.K183	NT.I105	cb1_off_allo	0	1.45	0	0	2	1
NT.D104	NT.M103	cb1_off_allo	0	1.39	0	0	2	1
NT.D104	NT.N101	cb1_off_allo	0	1.35	0	0	2	2

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Difference Members
	Id	Description
	cb1_off_allo	6KQI-CB₁-PubMed 104895-ORG27569
	cb1_off	5TGZ-CB₁-AM6538 5U09-CB₁-Taranabant

Network Difference
Value	cb1_off_allo	cb1_off
I_min	3.23	3.4
Number of Linked Nodes	265	285
Number of Specific Nodes	3 (1.13%)	23 (8.07%)
Number of Shared Nodes	262 (98.87%)	262 (91.93%)
Number of Links	297	318
Number of Specific Links	132 (44.44%)	153 (48.11%)
Number of Shared Links	165 (55.56%)	165 (51.89%)
Number of Hubs	39	46
Number of Specific Hubs	18 (46.15%)	25 (54.35%)
Number of Shared Hubs	21 (53.85%)	21 (45.65%)
Average % Shared Neighbours (Jaccard)	41.17
Average % Shared Neighbours (Otsuka)	49.21
Average % Shared Neighbours (Overlap Coefficient)	56.30
Average % Shared Cliques (k3-6)	77.91
Graphlets Similarity	0.617932

Paths Difference
Value	cb1_off_allo	cb1_off
Number Of Nodes in MetaPath	53	58
Specific Nodes in MetaPath	27 (50.94%)	32 (55.17%)
Shared Nodes in MetaPath	262 (98.87%)	262 (98.87%)
Number Of Links MetaPath	55	60
Specific Links in MetaPath	40 (72.73%)	45 (75.00%)
Shared Links in MetaPath	165 (55.56%)	165 (55.56%)
Number of Shortest Paths	56988	62483
Length Of Smallest Path	3	3
Average Path Length	12.3588	14.0211
Length of Longest Path	28	31
Minimum Path Strength	1.365	0.7525
Average Path Strength	6.73898	6.63909
Maximum Path Strength	22.075	23.9225
Minimum Path Correlation	0.7	0.7
Average Path Correlation	0.922697	0.918223
Maximum Path Correlation	0.99	0.99
Minimum % Of Corr. Nodes	4.16667	3.44828
Average % Of Corr. Nodes	48.715	41.5775
Maximum % Of Corr. Nodes	100	100
Minimum Path Hubs %	0	0
Average Path Hubs %	48.3957	48.0755
Maximum Path Hubs %	100	100

Details about the values in these tables can be found in the corresponding documentation page .

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