psnGPCR

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Orange: nodes, hubs and links specific of cb1_on_allo network

Green: nodes, hubs and links shared by both networks

Purple: nodes, hubs and links specific of cb1_on network

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Owner: the name of the network the link belong to or "Shared" if the corresponding link is present in both networks.

Strength: the interaction strength between the two nodes or 0 if the link is not present.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Owner	cb1_on_allo Int. Strength	cb1_on Int. Strength	cb1_on_allo Hub1?	cb1_on Hub1?	cb1_on_allo Hub2?	cb1_on Hub2?	ConSurf1	ConSurf2
1	NT.E106	NT.F108	cb1_on_allo	7	0	No	No	No	No	4	5
2	NT.C107	NT.M109	cb1_on_allo	3.24	0	No	No	No	No	2	3
3	E1.H181	NT.M109	cb1_on_allo	3.94	0	No	No	No	No	3	3
4	7x28	NT.V110	cb1_on_allo	6.07	0	No	No	No	No	3	3
5	1x29	1x32	cb1_on_allo	4.74	0	No	No	No	No	2	4
6	1x33	1x37	cb1_on_allo	2.98	0	No	No	No	No	5	4
7	1x38	1x39	cb1_on_allo	4.5	0	No	No	No	No	5	7
8	1x39	2x61	cb1_on_allo	2.64	0	No	No	Yes	Yes	7	5
9	1x42	7x43	cb1_on_allo	2.77	0	Yes	No	No	No	6	5
10	1x42	7x47	cb1_on_allo	4.42	0	Yes	No	No	Yes	6	7
11	1x44	1x45	cb1_on_allo	2.59	0	No	No	No	No	5	4
12	1x46	1x47	cb1_on_allo	3.17	0	Yes	Yes	No	No	7	6
13	1x46	1x49	cb1_on_allo	2.82	0	Yes	Yes	Yes	No	7	8
14	1x49	1x50	cb1_on_allo	15.77	0	Yes	No	Yes	No	8	9
15	1x50	2x51	cb1_on_allo	6.87	0	Yes	No	No	No	9	7
16	1x53	1x57	cb1_on_allo	3.07	0	Yes	No	Yes	No	9	7
17	1x53	2x47	cb1_on_allo	3.39	0	Yes	No	No	No	9	9
18	1x57	1x58	cb1_on_allo	2.85	0	Yes	No	No	No	7	4
19	I1x48	I1x50	cb1_on_allo	14.58	0	Yes	No	Yes	Yes	6	9
20	8x53	I1x48	cb1_on_allo	2.77	0	No	No	Yes	No	7	6
21	8x57	I1x48	cb1_on_allo	4.96	0	No	No	Yes	No	5	6
22	2x37	I1x50	cb1_on_allo	2.43	0	Yes	No	Yes	Yes	5	9
23	8x53	I1x50	cb1_on_allo	4.73	0	No	No	Yes	Yes	7	9
24	2x37	2x38	cb1_on_allo	2.88	0	Yes	No	Yes	No	5	5
25	2x37	2x39	cb1_on_allo	2.64	0	Yes	No	No	No	5	8
26	2x38	4x42	cb1_on_allo	3.74	0	Yes	No	No	No	5	7
27	2x40	2x43	cb1_on_allo	2.42	0	Yes	Yes	No	No	9	8
28	2x41	4x39	cb1_on_allo	9.03	0	No	No	No	Yes	3	1
29	2x46	3x39	cb1_on_allo	3	0	Yes	Yes	No	No	9	9
30	2x52	2x53	cb1_on_allo	5.13	0	Yes	No	No	No	6	8
31	2x52	Alloh34	cb1_on_allo	3.42	0	Yes	No	Yes	No	6	0
32	2x56	Alloh34	cb1_on_allo	11.76	0	No	No	Yes	No	5	0
33	2x57	7x38	cb1_on_allo	2.64	0	No	No	No	No	7	6
34	2x64	3x25	cb1_on_allo	5.36	0	No	Yes	No	Yes	4	9
35	E1.F180	E1.R182	cb1_on_allo	12.83	0	No	No	No	No	4	4
36	3x22	3x26	cb1_on_allo	4.86	0	Yes	Yes	No	No	3	5
37	3x27	Alloh34	cb1_on_allo	9.03	0	No	No	Yes	No	5	0
38	3x28	Alloh34	cb1_on_allo	3.48	0	No	No	Yes	No	6	0
39	3x30	Alloh34	cb1_on_allo	8.45	0	No	No	Yes	No	6	0
40	3x31	Alloh34	cb1_on_allo	8.45	0	No	No	Yes	No	4	0
41	3x34	Alloh34	cb1_on_allo	2.6	0	No	No	Yes	No	5	0
42	3x43	5x54	cb1_on_allo	2.85	0	No	No	No	No	8	8
43	3x46	7x53	cb1_on_allo	3.75	0	No	No	Yes	Yes	9	9
44	3x49	I2x57	cb1_on_allo	4.38	0	No	No	Yes	No	9	6
45	3x51	5x56	cb1_on_allo	3.97	0	Yes	No	No	No	8	4
46	I2x52	I2x55	cb1_on_allo	5.53	0	No	No	No	No	5	4
47	4x50	4x54	cb1_on_allo	2.35	0	Yes	Yes	No	No	9	4
48	4x55	4x59	cb1_on_allo	8.94	0	No	No	No	No	3	5
49	4x57	Alloh34	cb1_on_allo	2.6	0	No	No	Yes	No	7	0
50	4x58	Alloh34	cb1_on_allo	6.14	0	No	No	Yes	No	5	0
51	4x61	5x39	cb1_on_allo	2.34	0	No	No	No	Yes	5	7
52	E2.Q261	E2.W255	cb1_on_allo	3.29	0	Yes	No	No	Yes	1	5
53	5x38	E2.W255	cb1_on_allo	7.28	0	No	No	No	Yes	5	5
54	E2.H270	E2.N256	cb1_on_allo	3.83	0	Yes	Yes	No	Yes	3	6
55	E2.C257	E2.S262	cb1_on_allo	6.89	0	No	No	No	No	9	3
56	E2.C257	E2.H270	cb1_on_allo	7.37	0	No	No	Yes	Yes	9	3
57	E2.K259	E2.L260	cb1_on_allo	7.05	0	No	No	No	No	4	3
58	E2.L260	E2.Q261	cb1_on_allo	6.65	0	No	No	Yes	No	3	1
59	5x37	E2.Q261	cb1_on_allo	2.55	0	No	No	Yes	No	3	1
60	5x38	E2.Q261	cb1_on_allo	4.25	0	No	No	Yes	No	5	1
61	E2.F268	E2.S265	cb1_on_allo	5.28	0	Yes	Yes	No	No	5	4
62	E2.I271	E2.S265	cb1_on_allo	7.74	0	Yes	No	No	No	3	4
63	7x31	E2.I267	cb1_on_allo	4.36	0	No	No	No	No	2	4
64	5x40	E2.F268	cb1_on_allo	4.87	0	Yes	No	Yes	Yes	5	5
65	6x55	E2.F268	cb1_on_allo	6.22	0	No	No	Yes	Yes	6	5
66	6x58	E2.F268	cb1_on_allo	2.39	0	Yes	No	Yes	Yes	4	5
67	E2.P269	Lig	cb1_on_allo	3.49	0	No	No	Yes	Yes	3	0
68	5x39	E2.I271	cb1_on_allo	4.84	0	No	Yes	Yes	No	7	3
69	5x40	E2.I271	cb1_on_allo	2.85	0	Yes	No	Yes	No	5	3
70	5x37	5x38	cb1_on_allo	8.47	0	No	No	No	No	3	5
71	5x40	6x58	cb1_on_allo	2.71	0	Yes	No	Yes	No	5	4
72	5x43	5x44	cb1_on_allo	2.35	0	Yes	Yes	Yes	Yes	6	5
73	5x46	5x50	cb1_on_allo	2.98	0	No	No	No	No	6	8
74	5x49	5x53	cb1_on_allo	5.24	0	No	No	No	No	6	6
75	5x54	5x58	cb1_on_allo	2.42	0	No	No	Yes	Yes	8	9
76	5x61	5x62	cb1_on_allo	2.85	0	Yes	No	Yes	No	9	6
77	5x61	6x37	cb1_on_allo	2.85	0	Yes	No	No	No	9	8
78	5x63	5x64	cb1_on_allo	9.28	0	No	No	No	No	3	5
79	5x63	5x67	cb1_on_allo	7.41	0	No	No	No	No	3	5
80	5x70	5x74	cb1_on_allo	5.73	0	No	No	No	No	5	4
81	5x72	I2.T313	cb1_on_allo	6.02	0	No	No	No	No	7	3
82	6x24	6x28	cb1_on_allo	10.09	0	No	No	No	No	2	4
83	6x25	6x26	cb1_on_allo	5.22	0	No	No	No	No	3	5
84	6x36	6x37	cb1_on_allo	5.9	0	No	No	No	No	8	8
85	6x39	6x43	cb1_on_allo	2.98	0	No	No	No	No	7	6
86	6x50	7x37	cb1_on_allo	3.77	0	No	No	No	No	9	5
87	6x51	7x37	cb1_on_allo	3.17	0	Yes	No	No	No	7	5
88	6x51	7x41	cb1_on_allo	3.17	0	Yes	No	No	No	7	7
89	7x27	7x30	cb1_on_allo	7.08	0	No	No	No	No	1	3
90	7x29	7x32	cb1_on_allo	2.95	0	No	No	No	No	4	1
91	7x30	7x31	cb1_on_allo	7.27	0	No	No	No	No	3	2
92	7x32	7x36	cb1_on_allo	3.89	0	No	No	No	No	1	4
93	7x49	7x53	cb1_on_allo	2.33	0	No	No	Yes	Yes	9	9
94	8x47	8x50	cb1_on_allo	3	0	No	No	No	No	8	8
95	5x71	5x75	cb1_on_allo	2.13	0	No	No	No	No	4	5
96	6x57	6x60	cb1_on_allo	2.06	0	No	No	No	No	4	5
97	5x69	6x27	cb1_on_allo	1.79	0	No	No	No	No	5	4
98	1x53	7x50	cb1_on_allo	1.77	0	Yes	No	No	No	9	9
99	I1.C149	I1x49	cb1_on_allo	1.72	0	No	No	No	No	7	5
100	4x43	4x47	cb1_on_allo	1.71	0	No	No	No	No	1	4
101	1x36	2x66	cb1_on_allo	1.7	0	No	No	No	No	5	4
102	4x63	E2.N256	cb1_on_allo	1.7	0	No	No	No	Yes	5	6
103	4x56	4x60	cb1_on_allo	1.69	0	No	No	No	No	5	6
104	1x39	2x58	cb1_on_allo	1.62	0	No	No	No	No	7	7
105	I2x52	I2x56	cb1_on_allo	1.62	0	No	No	No	No	5	4
106	5x48	5x49	cb1_on_allo	1.62	0	No	No	No	No	5	6
107	5x65	6x29	cb1_on_allo	1.61	0	No	No	No	No	8	6
108	1x47	2x55	cb1_on_allo	1.6	0	No	No	No	No	6	4
109	4x43	4x44	cb1_on_allo	1.6	0	No	No	No	No	1	3
110	7x32	7x33	cb1_on_allo	1.59	0	No	No	No	No	1	4
111	7x54	7x55	cb1_on_allo	1.58	0	No	No	No	No	7	5
112	1x41	1x44	cb1_on_allo	1.57	0	No	No	No	No	4	5
113	1x56	1x57	cb1_on_allo	1.54	0	No	No	Yes	No	8	7
114	3x52	I2x57	cb1_on_allo	1.54	0	No	No	Yes	No	5	6
115	I2x56	I2x57	cb1_on_allo	1.54	0	No	No	Yes	No	4	6
116	5x55	5x59	cb1_on_allo	1.52	0	No	No	No	No	5	3
117	3x41	3x44	cb1_on_allo	1.51	0	No	No	No	Yes	5	7
118	I1x49	I1x50	cb1_on_allo	1.5	0	No	No	Yes	Yes	5	9
119	3x40	5x51	cb1_on_allo	1.49	0	No	No	No	No	7	6
120	5x40	6x59	cb1_on_allo	1.49	0	Yes	No	No	Yes	5	4
121	1x38	1x41	cb1_on_allo	1.47	0	No	No	No	No	5	4
122	1x40	1x44	cb1_on_allo	1.47	0	No	No	No	No	3	5
123	4x48	4x51	cb1_on_allo	1.47	0	No	No	No	No	3	4
124	E2.D266	E2.V263	cb1_on_allo	1.46	0	No	Yes	No	No	4	4
125	2x38	2x42	cb1_on_allo	1.44	0	Yes	No	No	Yes	5	8
126	5x62	6x33	cb1_on_allo	1.38	0	Yes	No	No	No	6	8
127	E1.H181	NT.L111	cb1_on_allo	1.29	0	No	No	No	Yes	3	4
128	5x71	5x74	cb1_on_allo	1.17	0	No	No	No	No	4	4
129	E2.P269	NT.F108	Shared	4.33	7.70667	No	No	No	No	3	5
130	7x31	NT.V110	Shared	9.11	4.55333	No	No	No	No	2	3
131	1x32	NT.L111	Shared	15.97	3.54667	No	No	No	Yes	4	4
132	2x65	NT.L111	Shared	5.14	3	No	Yes	No	Yes	4	4
133	1x28	1x29	Shared	6.52	9.23	No	No	No	No	6	2
134	1x28	1x31	Shared	11.88	16.2867	No	No	No	No	6	2
135	1x32	2x66	Shared	5.73	2.38667	No	No	No	No	4	4
136	1x35	2x61	Shared	2.51	2.93333	No	No	Yes	Yes	5	5
137	1x35	7x36	Shared	5.02	7.53333	No	No	No	No	5	4
138	1x38	7x39	Shared	5.65	4.71	No	No	No	No	5	5
139	1x42	7x42	Shared	6.92	2.30333	Yes	No	No	No	6	7
140	1x43	1x46	Shared	5.46	3.03333	No	No	Yes	Yes	6	7
141	1x46	2x54	Shared	9.59	5.33	Yes	Yes	No	Yes	7	7
142	1x46	7x47	Shared	6.28	9.42	Yes	Yes	No	Yes	7	7
143	1x49	7x50	Shared	12.58	5.24	Yes	No	No	No	8	9
144	1x50	2x50	Shared	4.04	3.59333	Yes	No	Yes	Yes	9	9
145	1x50	7x50	Shared	6.52	2.71667	Yes	No	No	No	9	9
146	1x53	7x54	Shared	3.39	2.83	Yes	No	No	No	9	7
147	1x54	1x58	Shared	2.77	1.38333	No	No	No	No	7	4
148	1x54	2x47	Shared	3.15	3.15333	No	No	No	No	7	9
149	1x54	2x48	Shared	4.47	3.47667	No	No	No	No	7	6
150	1x56	8x54	Shared	2.62	2.18333	No	No	No	No	8	7
151	1x57	2x43	Shared	2.94	1.96	Yes	No	No	No	7	8
152	1x59	I1x48	Shared	9.03	5.64333	No	No	Yes	No	5	6
153	2x40	I1x50	Shared	7.03	7.42333	Yes	Yes	Yes	Yes	9	9
154	2x37	2x40	Shared	9.26	5.49	Yes	No	Yes	Yes	5	9
155	2x38	I2x57	Shared	5.3	2.94333	Yes	No	Yes	No	5	6
156	2x39	2x40	Shared	5.09	3.39	No	No	Yes	Yes	8	9
157	2x40	8x49	Shared	5.75	4.6	Yes	Yes	No	Yes	9	6
158	2x40	8x50	Shared	3.52	4.29667	Yes	Yes	No	No	9	8
159	2x42	3x45	Shared	13.4	10.9633	No	Yes	No	No	8	6
160	2x45	3x42	Shared	4.89	4.34667	No	No	No	No	9	8
161	2x45	4x46	Shared	7.93	6.16333	No	No	No	No	9	8
162	2x46	2x50	Shared	5.43	3.62	Yes	Yes	Yes	Yes	9	9
163	2x46	3x42	Shared	3	7.01	Yes	Yes	No	No	9	8
164	2x46	3x43	Shared	4.15	4.15333	Yes	Yes	No	No	9	8
165	2x49	4x50	Shared	2.59	2.59	No	No	Yes	Yes	8	9
166	2x50	3x39	Shared	5.89	3.92667	Yes	Yes	No	No	9	9
167	2x50	7x46	Shared	11.78	9.81667	Yes	Yes	No	No	9	9
168	2x52	2x56	Shared	2.85	2.38	Yes	No	No	No	6	5
169	2x52	3x35	Shared	4.5	2	Yes	No	No	No	6	7
170	2x53	3x35	Shared	3.71	3.71	No	No	No	No	8	7
171	2x54	7x42	Shared	3	2.5	No	Yes	No	No	7	7
172	2x57	3x32	Shared	10.49	4.37	No	No	No	Yes	7	7
173	2x57	Lig	Shared	12.09	8.51	No	No	Yes	Yes	7	0
174	2x59	2x63	Shared	11.49	6.13	No	No	No	No	7	3
175	2x60	3x28	Shared	3.06	7.65	No	No	No	No	4	6
176	2x60	Lig	Shared	5.32	4.44	No	No	Yes	Yes	4	0
177	2x61	2x65	Shared	13.58	6.79	Yes	Yes	No	Yes	5	4
178	2x61	Lig	Shared	4.32	3.46	Yes	Yes	Yes	Yes	5	0
179	2x63	E1.R182	Shared	7.15	6.35333	No	No	No	No	3	4
180	2x64	2x65	Shared	5.66	10.5567	No	Yes	No	Yes	4	4
181	2x64	Lig	Shared	10.36	11	No	Yes	Yes	Yes	4	0
182	2x66	E1.F180	Shared	3.93	4.80667	No	No	No	No	4	4
183	3x24	E1.D184	Shared	5.84	4.38	No	No	No	No	5	2
184	3x21	3x23	Shared	2.98	3.47667	No	No	No	No	7	1
185	3x21	3x24	Shared	4.85	3.77	No	No	No	No	7	5
186	3x22	3x23	Shared	4.82	3.61667	Yes	Yes	No	No	3	1
187	3x22	E2.N256	Shared	6.03	3.61667	Yes	Yes	No	Yes	3	6
188	3x22	E2.E258	Shared	6.98	9.69333	Yes	Yes	No	No	3	1
189	3x22	E2.H270	Shared	5.64	6.39667	Yes	Yes	Yes	Yes	3	3
190	3x25	3x29	Shared	2.44	3.65333	No	Yes	No	No	9	4
191	3x25	E2.P269	Shared	10.11	7.22	No	Yes	No	No	9	3
192	3x26	4x61	Shared	5.54	9.22667	No	No	No	No	5	5
193	3x29	Lig	Shared	3.92	3.63667	No	No	Yes	Yes	4	0
194	3x32	3x36	Shared	5.24	3.49333	No	Yes	No	No	7	7
195	3x32	Lig	Shared	3.17	4.24667	No	Yes	Yes	Yes	7	0
196	3x33	5x43	Shared	3.64	3.64	No	No	Yes	Yes	6	6
197	3x33	Lig	Shared	3.13	9.01667	No	No	Yes	Yes	6	0
198	3x36	7x41	Shared	5.59	8.84667	No	No	No	No	7	7
199	3x36	Lig	Shared	6.04	4.75	No	No	Yes	Yes	7	0
200	3x37	4x53	Shared	3.36	2.24	No	No	No	No	6	8
201	3x37	5x43	Shared	4.85	4.85	No	No	Yes	Yes	6	6
202	3x38	4x50	Shared	6.48	8.64333	No	No	Yes	Yes	7	9
203	3x40	5x50	Shared	5.96	2.48333	No	No	No	No	7	8
204	3x41	4x49	Shared	5.24	4.65667	No	No	No	No	5	6
205	3x43	7x53	Shared	3.52	4.69	No	No	Yes	Yes	8	9
206	3x44	3x48	Shared	8.79	7.53667	No	Yes	No	No	7	7
207	3x44	5x53	Shared	6.43	7.86	No	Yes	No	No	7	6
208	3x47	5x54	Shared	4.87	4.33	No	No	No	No	8	8
209	3x49	I2x53	Shared	8.05	8.43	No	No	Yes	Yes	9	7
210	3x50	5x58	Shared	8.23	6.85667	No	No	Yes	Yes	9	9
211	3x50	7x53	Shared	6.17	6.17	No	No	Yes	Yes	9	9
212	3x51	3x55	Shared	3.27	13.43	Yes	No	No	No	8	6
213	3x51	5x57	Shared	2.67	2.66667	Yes	No	No	No	8	7
214	3x51	5x60	Shared	12.91	13.9	Yes	No	Yes	Yes	8	4
215	3x53	I2x53	Shared	6.36	8.90333	No	No	Yes	Yes	8	7
216	3x54	5x61	Shared	10.3	2.94333	No	No	Yes	No	9	9
217	3x54	5x64	Shared	2.91	5.81667	No	No	No	No	9	5
218	3x55	3x56	Shared	10.16	7.14667	No	No	No	No	6	5
219	3x55	5x60	Shared	4.36	8.71	No	No	Yes	Yes	6	4
220	I2x53	I2x54	Shared	4.78	1.99	Yes	Yes	No	No	7	4
221	I2x53	I2x57	Shared	3.79	2.94333	Yes	Yes	Yes	No	7	6
222	4x38	4x40	Shared	3.5	5.82667	No	No	No	No	8	4
223	4x39	4x40	Shared	2.88	1.44	No	Yes	No	No	1	4
224	4x46	4x50	Shared	10.02	4.67667	No	No	Yes	Yes	8	9
225	4x56	5x42	Shared	3.77	3.76667	No	No	No	No	5	6
226	4x60	5x39	Shared	4.17	6.48667	No	No	No	Yes	6	7
227	5x36	E2.W255	Shared	11.17	6.32667	No	Yes	No	Yes	5	5
228	E2.C257	E2.C264	Shared	7.28	7.28	No	No	No	No	9	9
229	E2.E258	E2.H270	Shared	11.08	3.69333	No	No	Yes	Yes	1	3
230	5x36	E2.S262	Shared	8.83	3.43333	No	Yes	No	No	5	3
231	6x58	E2.D266	Shared	5.32	3.99333	Yes	No	No	Yes	4	4
232	E2.D266	E3.M371	Shared	12.48	6.93333	No	Yes	No	Yes	4	1
233	E2.F268	E2.I267	Shared	6.28	6.69667	Yes	Yes	No	No	5	4
234	6x58	E2.I267	Shared	15.39	7.46667	Yes	No	No	No	4	4
235	E2.F268	E2.I271	Shared	2.51	5.44	Yes	Yes	Yes	No	5	3
236	E2.F268	Lig	Shared	10.36	14.27	Yes	Yes	Yes	Yes	5	0
237	5x43	5x47	Shared	9.7	9.33	Yes	Yes	No	No	6	8
238	5x43	Lig	Shared	3.23	6.30333	Yes	Yes	Yes	Yes	6	0
239	5x44	6x52	Shared	4.28	2.85333	Yes	Yes	No	No	5	7
240	5x44	6x55	Shared	4.37	5.83333	Yes	Yes	No	No	5	6
241	5x45	5x48	Shared	3.71	1.23667	No	No	No	No	3	5
242	5x51	6x44	Shared	4.15	2.76667	No	No	No	No	6	9
243	5x51	6x48	Shared	3.42	3.8	No	No	Yes	Yes	6	8
244	5x55	6x41	Shared	4.47	3.97333	No	No	No	No	5	8
245	5x58	5x61	Shared	2.42	2.42	Yes	Yes	Yes	No	9	9
246	5x58	6x40	Shared	4.84	6.44667	Yes	Yes	No	No	9	8
247	5x58	6x41	Shared	3.52	4.68667	Yes	Yes	No	No	9	8
248	5x58	7x53	Shared	4.96	3.64	Yes	Yes	Yes	Yes	9	9
249	5x60	5x63	Shared	10.61	5.46667	Yes	Yes	No	No	4	3
250	5x60	5x64	Shared	7.17	11.1467	Yes	Yes	No	No	4	5
251	5x62	6x37	Shared	4.15	3.69	Yes	No	No	No	6	8
252	5x66	5x70	Shared	6.92	5.07333	No	No	No	No	5	5
253	5x66	6x30	Shared	10.08	7.98333	No	No	No	Yes	5	7
254	5x68	5x72	Shared	2.63	4.37667	No	No	No	No	7	7
255	5x68	6x29	Shared	3.94	1.75	No	No	No	No	7	6
256	6x35	7x56	Shared	3.71	0.826667	No	No	No	No	7	7
257	6x36	7x56	Shared	15.52	7.76333	No	No	No	No	8	7
258	6x39	7x52	Shared	2.85	6.18667	No	No	No	Yes	7	9
259	6x40	7x52	Shared	2.94	3.92333	No	No	No	Yes	8	9
260	6x40	7x53	Shared	2.42	4.83667	No	No	Yes	Yes	8	9
261	6x47	7x45	Shared	11.02	8.92333	No	No	No	No	8	9
262	6x48	6x51	Shared	4.56	4.17333	Yes	Yes	Yes	No	8	7
263	6x48	6x52	Shared	5.69	4.55333	Yes	Yes	No	No	8	7
264	6x48	7x41	Shared	3.92	4.35333	Yes	Yes	No	No	8	7
265	6x48	7x45	Shared	6.78	3.39	Yes	Yes	No	No	8	9
266	6x49	6x50	Shared	4.06	4.06	No	No	No	No	5	9
267	6x50	7x40	Shared	3.28	1.09333	No	No	No	No	9	7
268	6x51	7x34	Shared	2.44	2.84333	Yes	No	No	Yes	7	4
269	6x54	7x37	Shared	3.27	2.72667	No	No	No	No	4	5
270	6x57	E3.K370	Shared	7.17	4.37667	No	No	No	No	4	1
271	7x27	E3.K370	Shared	2.8	2.33	No	No	No	No	1	1
272	7x30	E3.M371	Shared	2.92	8.74667	No	No	No	Yes	3	1
273	7x34	Lig	Shared	19.86	3.74	No	Yes	Yes	Yes	4	0
274	7x43	7x47	Shared	4.42	1.96333	No	No	No	Yes	5	7
275	7x45	7x49	Shared	10.9	12.7133	No	No	No	No	9	9
276	8x52	8x56	Shared	5.58	0.926667	No	No	No	No	4	3
277	2x41	I1x51	Shared	2.26	2.26	No	No	No	Yes	3	8
278	2x44	2x47	Shared	1.95	1.95	No	No	No	No	6	9
279	5x44	5x45	Shared	1.76	1.17667	Yes	Yes	No	No	5	3
280	6x61	E3.M371	Shared	1.75	1.16333	No	No	No	Yes	3	1
281	4x62	4x63	Shared	1.71	0.57	No	No	No	No	5	5
282	4x59	4x60	Shared	1.64	2.73333	No	No	No	No	5	6
283	6x46	6x47	Shared	1.64	0.546667	No	No	No	No	5	8
284	6x38	6x42	Shared	1.6	1.06667	No	No	No	No	6	6
285	6x43	7x48	Shared	1.6	2.13667	No	No	No	No	6	6
286	5x62	6x34	Shared	1.58	2.63	Yes	No	No	No	6	7
287	5x65	6x33	Shared	1.58	1.58	No	No	No	No	8	8
288	2x58	2x62	Shared	1.54	1.53667	No	No	No	No	7	5
289	5x44	6x56	Shared	1.54	2.56	Yes	Yes	No	No	5	6
290	5x65	6x30	Shared	1.54	1.02667	No	No	No	Yes	8	7
291	5x69	6x30	Shared	1.54	5.14667	No	No	No	Yes	5	7
292	4x51	4x52	Shared	1.52	2.02667	No	No	No	Yes	4	5
293	1x28	1x30	Shared	1.49	2.98	No	No	No	No	6	5
294	1x41	1x42	Shared	1.47	1.47333	No	No	Yes	No	4	6
295	3x56	I2x50	Shared	1.44	1.92	No	No	No	No	5	8
296	1x51	2x51	Shared	1.38	0.923333	No	No	No	No	3	7
297	1x49	7x51	Shared	1.37	4.1	Yes	No	No	No	8	6
298	6x28	6x32	Shared	1.07	12.3767	No	No	No	No	4	7
299	NT.C107	NT.D104	cb1_on	0	3.11333	No	No	No	No	2	0
300	E1.K183	NT.I105	cb1_on	0	5.33	No	No	No	No	6	0
301	2x64	NT.M109	cb1_on	0	3.73	No	Yes	No	No	4	3
302	1x31	NT.L111	cb1_on	0	6.21333	No	No	No	Yes	2	4
303	1x31	7x36	cb1_on	0	5.07667	No	No	No	No	2	4
304	1x35	7x39	cb1_on	0	3.88667	No	No	No	No	5	5
305	1x46	7x46	cb1_on	0	3.2	Yes	Yes	No	No	7	9
306	1x47	2x51	cb1_on	0	4.47	No	No	No	No	6	7
307	1x49	7x47	cb1_on	0	4.23	Yes	No	No	Yes	8	7
308	1x50	2x47	cb1_on	0	3.64667	Yes	No	No	No	9	9
309	1x55	1x56	cb1_on	0	3.42	No	No	No	No	4	8
310	1x57	I1x50	cb1_on	0	2.85667	Yes	No	Yes	Yes	7	9
311	1x57	2x40	cb1_on	0	7.65667	Yes	No	Yes	Yes	7	9
312	1x59	8x57	cb1_on	0	10.07	No	No	No	No	5	5
313	1x60	I1x50	cb1_on	0	4.50667	No	No	Yes	Yes	6	9
314	2x37	8x49	cb1_on	0	12.7033	Yes	No	No	Yes	5	6
315	2x38	4x39	cb1_on	0	2.88333	Yes	No	No	Yes	5	1
316	2x39	3x49	cb1_on	0	3.92667	No	No	No	No	8	9
317	2x40	8x47	cb1_on	0	5.09	Yes	Yes	No	No	9	8
318	2x45	4x50	cb1_on	0	5.76667	No	No	Yes	Yes	9	9
319	2x46	7x49	cb1_on	0	3.20667	Yes	Yes	No	No	9	9
320	2x50	7x49	cb1_on	0	4.04	Yes	Yes	No	No	9	9
321	2x57	2x61	cb1_on	0	10.36	No	No	Yes	Yes	7	5
322	2x65	Lig	cb1_on	0	7.55	No	Yes	Yes	Yes	4	0
323	3x25	E1.D184	cb1_on	0	5.57333	No	Yes	No	No	9	2
324	3x23	3x24	cb1_on	0	2.95667	No	No	No	No	1	5
325	3x26	4x60	cb1_on	0	5.47333	No	No	No	No	5	6
326	3x26	E2.N256	cb1_on	0	4.12	No	No	No	Yes	5	6
327	3x27	4x61	cb1_on	0	2.84333	No	No	No	No	5	5
328	3x29	E2.I271	cb1_on	0	3.33	No	No	Yes	No	4	3
329	3x30	3x33	cb1_on	0	3.03333	No	No	No	No	6	6
330	3x44	5x50	cb1_on	0	6.09	No	Yes	No	No	7	8
331	3x46	3x50	cb1_on	0	3.45	No	No	No	No	9	9
332	4x38	4x41	cb1_on	0	4.00333	No	No	No	No	8	5
333	4x48	4x52	cb1_on	0	3.80667	No	No	No	Yes	3	5
334	4x59	E2.W255	cb1_on	0	3.8	No	No	No	Yes	5	5
335	4x63	E2.W255	cb1_on	0	2.81333	No	No	No	Yes	5	5
336	5x36	E2.C257	cb1_on	0	3.11333	No	Yes	No	No	5	9
337	5x37	E2.V263	cb1_on	0	3.95667	No	No	No	No	3	4
338	5x37	E2.S265	cb1_on	0	3.51	No	No	No	No	3	4
339	7x34	E2.I267	cb1_on	0	3.34667	No	Yes	No	No	4	4
340	7x34	E2.F268	cb1_on	0	2.85667	No	Yes	Yes	Yes	4	5
341	E2.H270	E2.P269	cb1_on	0	7.62667	Yes	Yes	No	No	3	3
342	5x36	5x38	cb1_on	0	6.74667	No	Yes	No	No	5	5
343	5x39	Lig	cb1_on	0	4.61667	No	Yes	Yes	Yes	7	0
344	5x40	5x44	cb1_on	0	3.32667	Yes	No	Yes	Yes	5	5
345	5x41	6x59	cb1_on	0	3.04333	No	No	No	Yes	4	4
346	5x43	6x48	cb1_on	0	3.43667	Yes	Yes	Yes	Yes	6	8
347	5x43	6x55	cb1_on	0	3.87667	Yes	Yes	No	No	6	6
348	5x47	5x51	cb1_on	0	3.94333	No	No	No	No	8	6
349	5x56	5x60	cb1_on	0	4.63333	No	No	Yes	Yes	4	4
350	5x58	6x37	cb1_on	0	6.64667	Yes	Yes	No	No	9	8
351	6x43	7x52	cb1_on	0	3.07333	No	No	No	Yes	6	9
352	6x54	7x34	cb1_on	0	7.95333	No	No	No	Yes	4	4
353	6x55	7x34	cb1_on	0	3.32	No	No	No	Yes	6	4
354	6x57	7x30	cb1_on	0	2.82	No	No	No	No	4	3
355	6x58	E3.M371	cb1_on	0	4.16	Yes	No	No	Yes	4	1
356	6x59	6x60	cb1_on	0	4.80667	No	Yes	No	No	4	5
357	7x38	Lig	cb1_on	0	3.61667	No	No	Yes	Yes	6	0
358	7x51	7x55	cb1_on	0	3.80333	No	No	No	No	6	5
359	7x52	7x53	cb1_on	0	2.82	No	Yes	Yes	Yes	9	9
360	8x47	8x49	cb1_on	0	3.43667	No	No	No	Yes	8	6
361	8x48	8x49	cb1_on	0	4.14667	No	No	No	Yes	5	6
362	8x52	8x55	cb1_on	0	3.38667	No	No	No	No	4	5
363	8x50	I1x50	cb1_on	0	2.76667	No	No	Yes	Yes	8	9
364	4x39	I1x51	cb1_on	0	3.55333	No	Yes	No	Yes	1	8
365	2x61	7x38	cb1_on	0	4.40667	Yes	Yes	No	No	5	6
366	2x64	E1.H181	cb1_on	0	3.39333	No	Yes	No	No	4	3
367	3x25	E2.H270	cb1_on	0	5.65667	No	Yes	Yes	Yes	9	3
368	5x39	E2.W255	cb1_on	0	5.46667	No	Yes	No	Yes	7	5
369	E2.E258	E2.N256	cb1_on	0	3.50667	No	No	No	Yes	1	6
370	7x31	E2.D266	cb1_on	0	2.76667	No	No	No	Yes	2	4
371	5x42	5x46	cb1_on	0	4.37	No	No	No	No	6	6
372	6x30	6x31	cb1_on	0	3.73333	No	Yes	No	No	7	5
373	7x55	7x56	cb1_on	0	2.83333	No	No	No	No	5	7
374	1x60	I1x51	cb1_on	0	4.39333	No	No	No	Yes	6	8
375	2x64	E1.R182	cb1_on	0	4.63333	No	Yes	No	No	4	4
376	E2.D266	E3.K370	cb1_on	0	5.53	No	Yes	No	No	4	1
377	6x57	6x59	cb1_on	0	4.62667	No	No	No	Yes	4	4
378	6x59	E3.M371	cb1_on	0	3.04333	No	Yes	No	Yes	4	1
379	1x37	1x41	cb1_on	0	2.64667	No	No	No	No	4	4
380	7x54	8x50	cb1_on	0	2.62667	No	No	No	No	7	8
381	2x42	3x46	cb1_on	0	2.59333	No	Yes	No	No	8	9
382	2x56	3x32	cb1_on	0	2.56	No	No	No	Yes	5	7
383	1x56	8x57	cb1_on	0	2.53667	No	No	No	No	8	5
384	I1x48	I1x51	cb1_on	0	2.48667	Yes	No	No	Yes	6	8
385	4x58	4x61	cb1_on	0	2.48333	No	No	No	No	5	5
386	8x48	8x51	cb1_on	0	2.47667	No	No	No	No	5	8
387	4x49	4x52	cb1_on	0	2.43	No	No	No	Yes	6	5
388	3x52	I2x53	cb1_on	0	2.42	No	No	Yes	Yes	5	7
389	5x39	5x42	cb1_on	0	2.40667	No	Yes	No	No	7	6
390	2x42	3x49	cb1_on	0	2.39	No	Yes	No	No	8	9
391	3x45	4x49	cb1_on	0	2.35333	No	No	No	No	6	6
392	E2.K259	E2.N256	cb1_on	0	2.33333	No	No	No	Yes	4	6
393	7x27	7x28	cb1_on	0	2.33333	No	No	No	No	1	3
394	7x27	7x29	cb1_on	0	2.29	No	No	No	No	1	4
395	1x60	8x53	cb1_on	0	2.28	No	No	No	No	6	7
396	2x37	I1x49	cb1_on	0	2.19667	Yes	No	No	No	5	5
397	5x37	E2.D266	cb1_on	0	2.19333	No	No	No	Yes	3	4
398	8x48	8x52	cb1_on	0	2.18333	No	No	No	No	5	4
399	3x34	4x54	cb1_on	0	2.16333	No	No	No	No	5	4
400	3x30	3x31	cb1_on	0	2.11	No	No	No	No	6	4
401	3x44	5x54	cb1_on	0	2.09333	No	Yes	No	No	7	8
402	1x39	2x62	cb1_on	0	2.06667	No	No	No	No	7	5
403	1x39	7x39	cb1_on	0	2.04667	No	No	No	No	7	5
404	3x40	6x48	cb1_on	0	2.04333	No	No	Yes	Yes	7	8
405	1x52	8x54	cb1_on	0	2.03	No	No	No	No	7	7
406	7x28	7x32	cb1_on	0	2.00333	No	No	No	No	3	1
407	3x52	I2x56	cb1_on	0	1.96333	No	No	No	No	5	4
408	3x31	3x34	cb1_on	0	1.95	No	No	No	No	4	5
409	I1.C149	I1x48	cb1_on	0	1.85667	No	No	Yes	No	7	6
410	4x39	I1.C149	cb1_on	0	1.85667	No	Yes	No	No	1	7
411	2x42	4x42	cb1_on	0	1.84667	No	Yes	No	No	8	7
412	2x63	E1.K183	cb1_on	0	1.84333	No	No	No	No	3	6
413	3x34	4x57	cb1_on	0	1.79	No	No	No	No	5	7
414	I2x50	I2x51	cb1_on	0	1.64333	No	No	No	No	8	7
415	1x47	2x54	cb1_on	0	1.61667	No	No	No	Yes	6	7
416	2x54	2x55	cb1_on	0	1.61667	No	Yes	No	No	7	4
417	5x69	6x29	cb1_on	0	1.61	No	No	No	No	5	6
418	6x27	6x30	cb1_on	0	1.54333	No	No	No	Yes	4	7
419	6x42	6x46	cb1_on	0	1.53667	No	No	No	No	6	5
420	5x64	5x67	cb1_on	0	1.53	No	No	No	No	5	5
421	1x39	1x40	cb1_on	0	1.5	No	No	No	No	7	3
422	5x61	6x33	cb1_on	0	1.42667	Yes	No	No	No	9	8
423	NT.C107	NT.F108	cb1_on	0	1.39667	No	No	No	No	2	5
424	3x56	I2x52	cb1_on	0	1.38	No	No	No	No	5	5
425	1x32	1x33	cb1_on	0	1.33	No	No	No	No	4	5
426	4x43	4x46	cb1_on	0	1.31	No	No	No	No	1	8
427	1x45	7x47	cb1_on	0	1.29667	No	No	No	Yes	4	7
428	E2.L260	E2.W255	cb1_on	0	1.14	No	No	No	Yes	3	5
429	1x36	2x62	cb1_on	0	1.08333	No	No	No	No	5	5
430	3x45	4x45	cb1_on	0	1.05333	No	No	No	No	6	5
431	6x54	7x33	cb1_on	0	1.02667	No	No	No	No	4	4
432	5x72	I3.T313	cb1_on	0	1.00333	No	No	No	No	7	0
433	5x75	5x76	cb1_on	0	1	No	No	No	No	5	4
434	5x59	6x41	cb1_on	0	0.943333	No	No	No	No	3	8
435	6x51	7x40	cb1_on	0	0.923333	Yes	No	No	No	7	7
436	5x67	5x71	cb1_on	0	0.88	No	No	No	No	5	4
437	NT.D104	NT.E106	cb1_on	0	0.866667	No	No	No	No	0	4
438	6x28	6x31	cb1_on	0	0.836667	No	No	No	No	4	5
439	I2x55	I2x56	cb1_on	0	0.836667	No	No	No	No	4	4
440	5x45	5x49	cb1_on	0	0.613333	No	No	No	No	3	6
441	5x76	I3.T313	cb1_on	0	0.606667	No	No	No	No	4	0
442	4x47	4x51	cb1_on	0	0.563333	No	No	No	No	4	4
443	5x73	6x27	cb1_on	0	0.54	No	No	No	No	4	4
444	1x34	1x38	cb1_on	0	0.526667	No	No	No	No	5	5
445	7x35	NT.L111	cb1_on	0	0.526667	No	No	No	Yes	4	4
446	5x55	6x45	cb1_on	0	0.513333	No	No	No	No	5	6
447	4x52	4x55	cb1_on	0	0.513333	No	Yes	No	No	5	3
448	4x41	4x44	cb1_on	0	0.506667	No	No	No	No	5	3

Orange: nodes, hubs and links specific of cb1_on_allo network

Green: nodes, hubs and links shared by both networks

Purple: nodes, hubs and links specific of cb1_on network

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Owner: the name of the network the hub belong to or "Shared" if the corresponding hub is present in both networks.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub in the corresponding network.

Num Of Links: the number of links of the corresponding hub in the corresponding network.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Owner	cb1_on_allo Avg Int. Strength	cb1_on Avg Int. Strength	cb1_on_allo Num Of Links	cb1_on Num Of Links	ConSurf
1	1x42	cb1_on_allo	3.895	1.88833	4	2	6
2	1x49	cb1_on_allo	8.135	4.52333	4	3	8
3	1x50	cb1_on_allo	8.3	3.31889	4	3	9
4	1x53	cb1_on_allo	2.905	2.83	4	1	9
5	1x57	cb1_on_allo	2.6	4.15778	4	3	7
6	I1x48	cb1_on_allo	7.835	3.32889	4	3	6
7	2x37	cb1_on_allo	4.3025	6.79667	4	3	5
8	2x38	cb1_on_allo	3.34	2.91333	4	2	5
9	2x52	cb1_on_allo	3.975	2.19	4	2	6
10	3x51	cb1_on_allo	5.705	9.99889	4	3	8
11	I2x57	cb1_on_allo	3.31	2.94333	5	2	6
12	E2.Q261	cb1_on_allo	4.185	0	4	0	1
13	E2.I271	cb1_on_allo	4.485	4.385	4	2	3
14	5x40	cb1_on_allo	2.98	3.32667	4	1	5
15	5x61	cb1_on_allo	4.605	2.26333	4	3	9
16	5x62	cb1_on_allo	2.49	3.16	4	2	6
17	6x51	cb1_on_allo	3.335	2.64667	4	3	7
18	6x58	cb1_on_allo	6.4525	5.20667	4	3	4
19	Alloh34	cb1_on_allo	6.21444	0	9	0	0
20	1x46	Shared	5.464	5.24583	5	4	7
21	I1x50	Shared	6.054	4.38833	5	4	9
22	2x40	Shared	5.51167	5.42095	6	7	9
23	2x46	Shared	3.895	4.4975	4	4	9
24	2x50	Shared	6.785	4.99933	4	5	9
25	2x61	Shared	5.7625	5.59	4	5	5
26	3x22	Shared	5.666	5.83083	5	4	3
27	I2x53	Shared	5.745	4.93733	4	5	7
28	4x50	Shared	5.36	5.41917	4	4	9
29	E2.F268	Shared	5.41571	7.31583	7	4	5
30	E2.H270	Shared	6.98	5.84333	4	4	3
31	5x43	Shared	4.754	5.23944	5	6	6
32	5x44	Shared	2.86	3.15	5	5	5
33	5x58	Shared	4.39833	5.11611	6	6	9
34	5x60	Shared	8.7625	8.77133	4	5	4
35	6x48	Shared	4.874	3.67857	5	7	8
36	7x53	Shared	3.85833	4.43133	6	5	9
37	Lig	Shared	7.1075	6.36833	12	14	0
38	NT.L111	cb1_on	7.46667	3.32167	3	4	4
39	I1x51	cb1_on	2.26	3.17333	1	4	8
40	2x42	cb1_on	7.42	4.44833	2	4	8
41	2x54	cb1_on	6.295	2.76583	2	4	7
42	2x64	cb1_on	7.12667	6.66267	3	5	4
43	2x65	cb1_on	8.12667	6.97417	3	4	4
44	3x25	cb1_on	5.97	5.52583	3	4	9
45	3x32	cb1_on	6.3	3.6675	3	4	7
46	3x44	cb1_on	5.57667	5.895	3	4	7
47	4x39	cb1_on	5.955	2.43333	2	4	1
48	4x52	cb1_on	1.52	2.19417	1	4	5
49	E2.W255	cb1_on	7.24667	3.90933	3	5	5
50	E2.N256	cb1_on	3.85333	3.39417	3	4	6
51	E2.D266	cb1_on	6.42	4.28333	3	5	4
52	5x36	cb1_on	10	4.905	2	4	5
53	5x39	cb1_on	3.78333	4.74417	3	4	7
54	6x30	cb1_on	4.38667	3.88667	3	5	7
55	6x59	cb1_on	1.49	3.88	1	4	4
56	E3.M371	cb1_on	5.71667	4.80933	3	5	1
57	7x34	cb1_on	11.15	4.01	2	6	4
58	7x47	cb1_on	5.04	4.2275	3	4	7
59	7x52	cb1_on	2.895	4.00083	2	4	9
60	8x49	cb1_on	5.75	6.22167	1	4	6

Orange: nodes, hubs and links specific of cb1_on_allo network

Green: nodes, hubs and links shared by both networks

Purple: nodes, hubs and links specific of cb1_on network

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Owner: the name of the network the link belong to or "Shared" if the corresponding link is present in both networks.

Recurrence: the relative Recurrence in the filtered pool of shortest paths.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Owner	cb1_on_allo Recurrence	cb1_on Recurrence	cb1_on_allo Hub1?	cb1_on Hub1?	cb1_on_allo Hub2?	cb1_on Hub2?	ConSurf1	ConSurf2
1	2x61	2x65	cb1_on_allo	23.5311	0.780883	Yes	Yes	No	Yes	5	4
2	2x64	2x65	cb1_on_allo	18.5991	0.776616	No	Yes	No	Yes	4	4
3	7x31	E2.I267	cb1_on_allo	15.1705	0	No	No	No	No	2	4
4	E2.F268	E2.I267	cb1_on_allo	16.854	9.57115	Yes	Yes	No	No	5	4
5	1x32	NT.L111	cb1_on_allo	28.3729	5.81609	No	No	No	Yes	4	4
6	1x29	1x32	cb1_on_allo	10.4472	0	No	No	No	No	2	4
7	1x32	2x66	cb1_on_allo	15.6163	2.92298	No	No	No	No	4	4
8	1x38	1x39	cb1_on_allo	33.5278	0	No	No	No	No	5	7
9	1x39	2x61	cb1_on_allo	35.9605	0	No	No	Yes	Yes	7	5
10	1x41	1x42	cb1_on_allo	31.9628	2.63281	No	No	Yes	No	4	6
11	1x38	1x41	cb1_on_allo	31.9818	0	No	No	No	No	5	4
12	1x42	7x47	cb1_on_allo	29.8335	0	Yes	No	No	Yes	6	7
13	1x46	7x47	cb1_on_allo	30.5354	4.12631	Yes	Yes	No	Yes	7	7
14	1x46	1x49	cb1_on_allo	32.1667	0	Yes	Yes	Yes	No	7	8
15	1x49	7x50	cb1_on_allo	22.8529	7.19863	Yes	No	No	No	8	9
16	7x49	7x53	cb1_on_allo	95.9169	0	No	No	Yes	Yes	9	9
17	6x48	7x41	cb1_on_allo	40.2428	5.44058	Yes	Yes	No	No	8	7
18	3x36	7x41	cb1_on_allo	40.3566	5.07361	No	No	No	No	7	7
19	3x36	Lig	cb1_on_allo	39.5457	1.03264	No	No	Yes	Yes	7	0
20	1x53	7x50	cb1_on_allo	45.3882	0	Yes	No	No	No	9	9
21	1x53	1x57	cb1_on_allo	37.682	0	Yes	No	Yes	No	9	7
22	1x57	2x43	cb1_on_allo	33.5467	1.25453	Yes	No	No	No	7	8
23	2x40	2x43	cb1_on_allo	32.4133	0	Yes	Yes	No	No	9	8
24	2x37	2x40	cb1_on_allo	17.8356	2.47066	Yes	No	Yes	Yes	5	9
25	2x37	2x38	cb1_on_allo	17.1006	0	Yes	No	Yes	No	5	5
26	2x45	3x42	cb1_on_allo	13.0554	7.80457	No	No	No	No	9	8
27	2x46	3x42	cb1_on_allo	15.1989	9.07617	Yes	Yes	No	No	9	8
28	2x45	4x46	cb1_on_allo	10.9025	2.60721	No	No	No	No	9	8
29	3x28	Alloh34	cb1_on_allo	17.0484	0	No	No	Yes	No	6	0
30	2x60	3x28	cb1_on_allo	18.547	1.19906	No	No	No	No	4	6
31	2x60	Lig	cb1_on_allo	19.927	2.35545	No	No	Yes	Yes	4	0
32	2x66	E1.F180	cb1_on_allo	10.4472	1.46362	No	No	No	No	4	4
33	3x22	3x26	cb1_on_allo	39.1331	0	Yes	Yes	No	No	3	5
34	3x26	4x61	cb1_on_allo	40.8925	4.43781	No	No	No	No	5	5
35	4x61	5x39	cb1_on_allo	42.6424	0	No	No	No	Yes	5	7
36	5x39	E2.I271	cb1_on_allo	52.9426	0	No	Yes	Yes	No	7	3
37	E2.F268	E2.I271	cb1_on_allo	53.4879	3.35822	Yes	Yes	Yes	No	5	3
38	3x22	E2.H270	cb1_on_allo	22.6443	3.07659	Yes	Yes	Yes	Yes	3	3
39	5x51	6x48	cb1_on_allo	10.4519	3.37103	No	No	Yes	Yes	6	8
40	3x43	5x54	cb1_on_allo	15.4313	0	No	No	No	No	8	8
41	5x54	5x58	cb1_on_allo	15.1563	0	No	No	Yes	Yes	8	9
42	5x36	E2.W255	cb1_on_allo	13.506	6.97248	No	Yes	No	Yes	5	5
43	5x36	E2.S262	cb1_on_allo	15.3981	1.20333	No	Yes	No	No	5	3
44	E2.C257	E2.S262	cb1_on_allo	17.2808	0	No	No	No	No	9	3
45	E2.C257	E2.H270	cb1_on_allo	21.0177	0	No	No	Yes	Yes	9	3
46	6x55	E2.F268	cb1_on_allo	19.1777	0	No	No	Yes	Yes	6	5
47	5x44	6x52	cb1_on_allo	24.6076	4.72797	Yes	Yes	No	No	5	7
48	5x61	5x62	cb1_on_allo	36.4822	0	Yes	No	Yes	No	9	6
49	5x66	6x30	cb1_on_allo	11.7987	2.66695	No	No	No	Yes	5	7
50	5x62	6x33	cb1_on_allo	32.2853	0	Yes	No	No	No	6	8
51	6x48	6x52	cb1_on_allo	24.527	5.87156	Yes	Yes	No	No	8	7
52	5x44	6x55	cb1_on_allo	19.0591	5.21442	Yes	Yes	No	No	5	6
53	1x50	7x50	cb1_on_allo	23.5501	8.35076	Yes	No	No	No	9	9
54	2x65	NT.L111	Shared	38.4076	13.7487	No	Yes	No	Yes	4	4
55	2x61	Lig	Shared	52.7149	14.1583	Yes	Yes	Yes	Yes	5	0
56	2x64	Lig	Shared	20.1878	10.2496	No	Yes	Yes	Yes	4	0
57	E2.F268	Lig	Shared	63.717	10.0405	Yes	Yes	Yes	Yes	5	0
58	2x46	2x50	Shared	34.5948	16.134	Yes	Yes	Yes	Yes	9	9
59	2x46	3x43	Shared	48.8974	94.4613	Yes	Yes	No	No	9	8
60	3x43	7x53	Shared	41.0253	94.0815	No	No	Yes	Yes	8	9
61	7x45	7x49	Shared	96.927	100	No	No	No	No	9	9
62	6x48	7x45	Shared	100	99.7866	Yes	Yes	No	No	8	9
63	6x48	6x51	Shared	42.135	23.6783	Yes	Yes	Yes	No	8	7
64	6x51	7x34	Shared	42.3389	22.2872	Yes	No	No	Yes	7	4
65	7x34	Lig	Shared	42.5807	13.0062	No	Yes	Yes	Yes	4	0
66	2x38	I2x57	Shared	11.9789	25.2998	Yes	No	Yes	No	5	6
67	5x58	7x53	Shared	69.3128	32.1101	Yes	Yes	Yes	Yes	9	9
68	5x60	5x64	Shared	16.3892	13.0019	Yes	Yes	No	No	4	5
69	3x54	5x64	Shared	23.3698	16.501	No	No	No	No	9	5
70	3x54	5x61	Shared	25.6604	17.5336	No	No	Yes	No	9	9
71	5x58	5x61	Shared	71.3046	36.8167	Yes	Yes	Yes	No	9	9
72	5x65	6x30	Shared	18.7651	17.9176	No	No	No	Yes	8	7
73	5x65	6x33	Shared	30.1845	19.1252	No	No	No	No	8	8
74	1x50	2x50	Shared	32.7168	15.6475	Yes	No	Yes	Yes	9	9
75	3x29	Lig	cb1_on	2.86907	18.7796	No	No	Yes	Yes	4	0
76	3x25	3x29	cb1_on	1.51278	18.2291	No	Yes	No	No	9	4
77	6x58	E2.D266	cb1_on	8.19462	19.5776	Yes	No	No	Yes	4	4
78	6x58	E2.I267	cb1_on	0.170721	34.2266	Yes	No	No	No	4	4
79	7x34	E2.I267	cb1_on	0	26.0038	No	Yes	No	No	4	4
80	2x65	Lig	cb1_on	0	14.0132	No	Yes	Yes	Yes	4	0
81	1x35	2x61	cb1_on	7.55916	14.0772	No	No	Yes	Yes	5	5
82	1x35	7x39	cb1_on	0	11.6194	No	No	No	No	5	5
83	1x46	7x46	cb1_on	0	17.269	Yes	Yes	No	No	7	9
84	2x50	7x46	cb1_on	1.93958	18.4212	Yes	Yes	No	No	9	9
85	2x50	7x49	cb1_on	0	19.4709	Yes	Yes	No	No	9	9
86	5x43	6x48	cb1_on	0	65.0139	Yes	Yes	Yes	Yes	6	8
87	5x43	Lig	cb1_on	7.70143	61.8135	Yes	Yes	Yes	Yes	6	0
88	1x46	2x54	cb1_on	1.41794	11.5938	Yes	Yes	No	Yes	7	7
89	2x39	2x40	cb1_on	1.30886	28.8713	No	No	Yes	Yes	8	9
90	2x39	3x49	cb1_on	0	29.8571	No	No	No	No	8	9
91	2x42	3x49	cb1_on	0	62.0098	No	Yes	No	No	8	9
92	2x42	3x46	cb1_on	0	70.6123	No	Yes	No	No	8	9
93	3x46	3x50	cb1_on	0	71.342	No	No	No	No	9	9
94	3x50	7x53	cb1_on	1.74041	59.7269	No	No	Yes	Yes	9	9
95	2x46	7x49	cb1_on	0	80.5419	Yes	Yes	No	No	9	9
96	1x56	8x57	cb1_on	0	13.8724	No	No	No	No	8	5
97	1x59	8x57	cb1_on	0	16.6588	No	No	No	No	5	5
98	1x59	I1x48	cb1_on	1.38	20.0981	No	No	Yes	No	5	6
99	I1x48	I1x51	cb1_on	0	15.831	Yes	No	No	Yes	6	8
100	4x39	I1x51	cb1_on	0	10.6465	No	Yes	No	Yes	1	8
101	2x38	4x39	cb1_on	0	24.3226	Yes	No	No	Yes	5	1
102	I2x53	I2x57	cb1_on	4.09257	26.3793	Yes	Yes	Yes	No	7	6
103	3x49	I2x53	cb1_on	0.00948452	32.4899	No	No	Yes	Yes	9	7
104	1x60	I1x51	cb1_on	0	10.9452	No	No	No	Yes	6	8
105	1x60	I1x50	cb1_on	0	12.8952	No	No	Yes	Yes	6	9
106	2x40	I1x50	cb1_on	8.83008	13.578	Yes	Yes	Yes	Yes	9	9
107	2x42	3x45	cb1_on	1.37525	11.6322	No	Yes	No	No	8	6
108	4x60	5x39	cb1_on	9.69318	10.6038	No	No	No	Yes	6	7
109	5x39	Lig	cb1_on	0	27.5741	No	Yes	Yes	Yes	7	0
110	5x39	E2.W255	cb1_on	0	13.2281	No	Yes	No	Yes	7	5
111	6x58	E3.M371	cb1_on	0	13.0617	Yes	No	No	Yes	4	1
112	5x61	6x33	cb1_on	0	20.1067	Yes	No	No	No	9	8
113	E2.D266	E3.K370	cb1_on	0	10.2283	No	Yes	No	No	4	1
114	3x50	5x58	cb1_on	0.199175	12.1314	No	No	Yes	Yes	9	9

Here, those paths that begin and end at given residue pair(s) or that pass through a residue are used to generate a novel metapath. Such a path filtering is particularly recommended if some information on allosteric residues is available. The selection syntax for a residue pair ("Pairs") is C:C:c534,A:A:?600 (the lower-case "c" stands for cytosine and "?" indicates any non standard amino acid or nucleotide residue). Selection of more than one apical residue pair has the following syntax: C:C:c534,A:A:?600,C:C:c534,A:A:E41. Only one residue can be selected as a tail ("Tail"). For midway residue(s), each residue must be separated by a comma as well e.g. A:A:?600,A:A:E41.

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Node1	Node2	Owner	Net1LinkStrength	Net2LinkStrength	Comm1	Comm2	Node1Shell	Node2Shell
E2.P269	NT.F108	Shared	7.70667	4.33	2	0	1	2
2x64	NT.M109	cb1_on	3.73	0	1	0	1	2
1x35	2x61	Shared	2.93333	2.51	0	0	2	1
2x57	2x61	cb1_on	10.36	0	1	1	1	1
2x57	Lig	Shared	8.51	12.09	1	1	1	0
2x60	3x28	Shared	7.65	3.06	0	0	1	2
2x60	Lig	Shared	4.44	5.32	0	0	1	0
2x61	2x65	Shared	6.79	13.58	1	0	1	1
2x61	Lig	Shared	3.46	4.32	1	0	1	0
2x64	2x65	Shared	10.5567	5.66	1	0	1	1
2x64	Lig	Shared	11	10.36	1	0	1	0
2x65	Lig	cb1_on	7.55	0	1	0	1	0
3x25	E2.P269	Shared	7.22	10.11	2	0	2	1
3x29	E2.I271	cb1_on	3.33	0	0	0	1	2
3x29	Lig	Shared	3.63667	3.92	0	0	1	0
3x30	3x33	cb1_on	3.03333	0	0	0	2	1
3x32	3x36	Shared	3.49333	5.24	1	1	1	1
3x32	Lig	Shared	4.24667	3.17	1	1	1	0
3x33	5x43	Shared	3.64	3.64	1	1	1	1
3x33	Lig	Shared	9.01667	3.13	1	1	1	0
3x36	7x41	Shared	8.84667	5.59	1	1	1	2
3x36	Lig	Shared	4.75	6.04	1	1	1	0
3x37	5x43	Shared	4.85	4.85	0	0	2	1
4x60	5x39	Shared	6.48667	4.17	0	0	2	1
E2.F268	E2.I267	Shared	6.69667	6.28	1	1	1	2
6x58	E2.I267	Shared	7.46667	15.39	1	1	2	2
7x34	E2.I267	cb1_on	3.34667	0	1	0	1	2
E2.F268	E2.I271	Shared	5.44	2.51	1	1	1	2
7x34	E2.F268	cb1_on	2.85667	0	1	0	1	1
E2.F268	Lig	Shared	14.27	10.36	1	1	1	0
E2.H270	E2.P269	cb1_on	7.62667	0	2	7	2	1
5x39	Lig	cb1_on	4.61667	0	0	0	1	0
5x40	5x44	cb1_on	3.32667	0	0	1	2	2
5x43	5x47	Shared	9.33	9.7	1	1	1	2
5x43	6x48	cb1_on	3.43667	0	1	1	1	2
5x43	6x55	cb1_on	3.87667	0	1	1	1	2
5x43	Lig	Shared	6.30333	3.23	1	1	1	0
5x44	6x55	Shared	5.83333	4.37	0	0	2	2
6x48	7x41	Shared	4.35333	3.92	0	1	2	2
6x51	7x34	Shared	2.84333	2.44	0	1	2	1
6x54	7x34	cb1_on	7.95333	0	0	0	2	1
6x55	7x34	cb1_on	3.32	0	0	0	2	1
7x34	Lig	Shared	3.74	19.86	1	0	1	0
7x38	Lig	cb1_on	3.61667	0	1	0	1	0
2x65	NT.L111	Shared	3	5.14	1	0	1	2
2x57	3x32	Shared	4.37	10.49	1	1	1	1
2x61	7x38	cb1_on	4.40667	0	1	0	1	1
2x64	E1.H181	cb1_on	3.39333	0	1	0	1	2
3x25	3x29	Shared	3.65333	2.44	2	0	2	1
3x25	E2.H270	cb1_on	5.65667	0	2	0	2	2
5x39	E2.W255	cb1_on	5.46667	0	0	0	1	2
6x48	6x51	Shared	4.17333	4.56	0	1	2	2
2x64	E1.R182	cb1_on	4.63333	0	1	0	1	2
2x56	3x32	cb1_on	2.56	0	0	5	2	1
5x39	5x42	cb1_on	2.40667	0	0	0	1	2
E1.H181	NT.M109	cb1_on_allo	0	3.94	0	0	2	2
1x39	2x61	cb1_on_allo	0	2.64	0	0	2	1
2x57	7x38	cb1_on_allo	0	2.64	1	1	1	1
2x64	3x25	cb1_on_allo	0	5.36	1	0	1	2
4x61	5x39	cb1_on_allo	0	2.34	0	0	2	1
E2.F268	E2.S265	cb1_on_allo	0	5.28	1	1	1	2
E2.I271	E2.S265	cb1_on_allo	0	7.74	0	1	2	2
5x40	E2.F268	cb1_on_allo	0	4.87	0	1	2	1
6x55	E2.F268	cb1_on_allo	0	6.22	0	0	2	1
6x58	E2.F268	cb1_on_allo	0	2.39	1	1	2	1
E2.P269	Lig	cb1_on_allo	0	3.49	2	0	1	0
5x39	E2.I271	cb1_on_allo	0	4.84	0	0	1	2
5x40	E2.I271	cb1_on_allo	0	2.85	0	1	2	2
5x40	6x58	cb1_on_allo	0	2.71	0	1	2	2
5x43	5x44	cb1_on_allo	0	2.35	1	1	1	2
6x51	7x41	cb1_on_allo	0	3.17	0	1	2	2
E1.H181	NT.L111	cb1_on_allo	0	1.29	0	0	2	2

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Difference Members
	Id	Description
	cb1_on_allo	7WV9-CB₁-PubMed 104895-ZCZ011-Gi2/&β;1/&γ;2
	cb1_on	8GHV-CB₁-PubChem 145964903-Gi1/&β;1/&γ;2 6KPG-CB₁-AM841-Gi1/&β;1/&γ;2 6N4B-CB₁-MDMB-Fubinaca-Gi1/&β;1/&γ;2

Network Difference
Value	cb1_on_allo	cb1_on
I_min	2.33	2.70667
Number of Linked Nodes	270	282
Number of Specific Nodes	8 (2.96%)	20 (7.09%)
Number of Shared Nodes	262 (97.04%)	262 (92.91%)
Number of Links	298	320
Number of Specific Links	128 (42.95%)	150 (46.88%)
Number of Shared Links	170 (57.05%)	170 (53.13%)
Number of Hubs	37	41
Number of Specific Hubs	19 (51.35%)	23 (56.10%)
Number of Shared Hubs	18 (48.65%)	18 (43.90%)
Average % Shared Neighbours (Jaccard)	39.90
Average % Shared Neighbours (Otsuka)	49.56
Average % Shared Neighbours (Overlap Coefficient)	58.84
Average % Shared Cliques (k3-6)	79.07
Graphlets Similarity	0.626775

Paths Difference
Value	cb1_on_allo	cb1_on
Number Of Nodes in MetaPath	70	58
Specific Nodes in MetaPath	39 (55.71%)	27 (46.55%)
Shared Nodes in MetaPath	262 (97.04%)	262 (97.04%)
Number Of Links MetaPath	74	61
Specific Links in MetaPath	53 (71.62%)	40 (65.57%)
Shared Links in MetaPath	170 (57.05%)	170 (57.05%)
Number of Shortest Paths	48329	48236
Length Of Smallest Path	3	3
Average Path Length	14.1597	13.2571
Length of Longest Path	34	30
Minimum Path Strength	1.47	0.895
Average Path Strength	5.26877	4.60333
Maximum Path Strength	12.5867	12.7583
Minimum Path Correlation	0.7	0.7
Average Path Correlation	0.93398	0.918247
Maximum Path Correlation	0.99	0.99
Minimum % Of Corr. Nodes	4.54545	3.57143
Average % Of Corr. Nodes	52.5853	44.883
Maximum % Of Corr. Nodes	100	100
Minimum Path Hubs %	0	0
Average Path Hubs %	41.837	40.438
Maximum Path Hubs %	100	100

Details about the values in these tables can be found in the corresponding documentation page .

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