psnGPCR

Press and hold down the left mouse button and move the mouse to rotate.
Press and hold down the central mouse button and move the mouse to translate.
Use the mouse wheel to zoom in or out.
Click on any atom on your molecule and the corresponding residue label will be placed beneath the viewer.

Orange: nodes, hubs and links specific of cck_off network

Green: nodes, hubs and links shared by both networks

Purple: nodes, hubs and links specific of cck_on network

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Owner: the name of the network the link belong to or "Shared" if the corresponding link is present in both networks.

Strength: the interaction strength between the two nodes or 0 if the link is not present.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Owner	cck_off Int. Strength	cck_on Int. Strength	cck_off Hub1?	cck_on Hub1?	cck_off Hub2?	cck_on Hub2?	ConSurf1	ConSurf2
1	2x60	Lig	cck_off	100	0	No	No	Yes	Yes	7	0
2	3x29	Lig	cck_off	100	0	No	No	Yes	Yes	6	0
3	6x51	Lig	cck_off	100	0	No	No	Yes	Yes	7	0
4	1x31	NT	cck_off	100	0	Yes	No	No	No	1	5
5	1x31	1x32	cck_off	100	0	Yes	No	No	No	1	4
6	1x42	7x43	cck_off	100	0	No	No	No	No	7	5
7	1x43	2x54	cck_off	100	0	Yes	No	No	No	5	7
8	1x46	7x46	cck_off	100	0	Yes	No	No	No	8	9
9	1x49	7x50	cck_off	100	0	No	No	No	No	8	9
10	1x53	7x53	cck_off	100	0	No	Yes	No	Yes	9	9
11	1x59	1x60	cck_off	100	0	No	No	No	No	5	6
12	2x38	3x49	cck_off	100	0	No	No	No	Yes	7	9
13	2x39	3x49	cck_off	100	0	No	No	No	Yes	8	9
14	2x39	3x50	cck_off	100	0	No	No	Yes	No	8	9
15	2x40	2x43	cck_off	100	0	No	No	No	No	9	8
16	2x42	4x45	cck_off	100	0	Yes	Yes	No	No	8	6
17	2x46	3x39	cck_off	100	0	No	No	No	No	9	9
18	2x48	4x50	cck_off	100	0	No	No	Yes	No	6	9
19	2x49	3x35	cck_off	100	0	No	No	No	No	8	6
20	2x52	4x50	cck_off	100	0	No	No	Yes	No	7	9
21	2x53	3x32	cck_off	100	0	Yes	No	No	No	8	7
22	2x53	6x48	cck_off	100	0	Yes	No	Yes	Yes	8	8
23	2x53	7x42	cck_off	100	0	Yes	No	Yes	Yes	8	7
24	2x59	3x24	cck_off	100	0	No	No	No	No	6	5
25	2x62	E1x52	cck_off	100	0	No	No	Yes	Yes	5	6
26	2x63	E1x52	cck_off	100	0	No	No	Yes	Yes	5	6
27	2x64	7x35	cck_off	100	0	No	No	No	No	6	5
28	2x66	E1x51	cck_off	100	0	No	No	No	No	4	4
29	E1x49	E2	cck_off	100	0	No	No	Yes	Yes	4	3
30	E1x50	E2	cck_off	100	0	Yes	Yes	Yes	Yes	8	3
31	3x26	E2	cck_off	100	0	No	No	Yes	Yes	5	3
32	3x29	4x61	cck_off	100	0	No	No	Yes	Yes	6	7
33	3x30	4x59	cck_off	100	0	No	No	No	No	6	4
34	3x31	4x54	cck_off	100	0	Yes	No	No	No	5	4
35	3x32	7x42	cck_off	100	0	No	No	Yes	Yes	7	7
36	3x36	6x52	cck_off	100	0	No	No	Yes	No	7	7
37	3x38	3x42	cck_off	100	0	Yes	No	No	No	8	8
38	3x38	4x49	cck_off	100	0	Yes	No	No	No	8	7
39	3x39	6x44	cck_off	100	0	No	No	Yes	No	9	9
40	3x40	3x41	cck_off	100	0	No	No	No	No	8	6
41	3x40	5x461	cck_off	100	0	No	No	No	No	8	7
42	3x40	6x44	cck_off	100	0	No	No	Yes	No	8	9
43	3x41	3x44	cck_off	100	0	No	No	No	No	6	7
44	3x41	5x50	cck_off	100	0	No	No	No	Yes	6	9
45	3x42	4x49	cck_off	100	0	No	No	No	No	8	7
46	3x43	6x41	cck_off	100	0	No	No	No	No	8	8
47	3x43	6x44	cck_off	100	0	No	No	Yes	No	8	9
48	3x44	5x54	cck_off	100	0	No	No	No	No	7	8
49	3x46	6x37	cck_off	100	0	No	No	No	No	9	8
50	3x49	3x50	cck_off	100	0	No	Yes	Yes	No	9	9
51	3x50	3x53	cck_off	100	0	Yes	No	No	No	9	8
52	3x50	3x54	cck_off	100	0	Yes	No	No	No	9	9
53	3x50	6x34	cck_off	100	0	Yes	No	No	No	9	8
54	3x54	5x65	cck_off	100	0	No	No	No	No	9	9
55	3x56	I2x53	cck_off	100	0	Yes	Yes	No	No	6	8
56	4x41	4x44	cck_off	100	0	Yes	Yes	No	No	7	4
57	6x58	E2x51	cck_off	100	0	No	No	No	No	4	4
58	E2x51	E3	cck_off	100	0	No	No	Yes	Yes	4	3
59	5x39	E2x52	cck_off	100	0	Yes	Yes	Yes	Yes	8	5
60	5x43	6x52	cck_off	100	0	No	No	Yes	No	7	7
61	5x47	6x52	cck_off	100	0	No	No	Yes	No	8	7
62	5x54	6x41	cck_off	100	0	No	No	No	No	8	8
63	5x58	6x38	cck_off	100	0	Yes	Yes	No	No	9	7
64	5x61	6x34	cck_off	100	0	No	No	No	No	9	8
65	5x65	6x31	cck_off	100	0	No	No	No	No	9	6
66	6x27	6x28	cck_off	100	0	No	No	No	No	4	5
67	6x36	6x40	cck_off	100	0	No	No	No	No	9	9
68	6x40	7x49	cck_off	100	0	No	No	Yes	No	9	9
69	6x44	6x45	cck_off	100	0	Yes	No	Yes	No	9	6
70	6x45	6x49	cck_off	100	0	Yes	No	No	No	6	6
71	7x32	7x33	cck_off	100	0	No	No	No	No	3	4
72	7x48	7x49	cck_off	100	0	No	No	Yes	No	7	9
73	7x49	7x53	cck_off	100	0	Yes	No	No	Yes	9	9
74	4x39	I1x48	cck_off	100	0	No	No	No	No	4	7
75	I1x49	I1x50	cck_off	100	0	No	No	No	No	6	8
76	3x51	5x61	cck_off	50	0	Yes	No	No	No	8	9
77	5x58	6x34	cck_off	50	0	Yes	Yes	No	No	9	8
78	1x39	2x57	cck_off	50	0	No	No	No	Yes	7	7
79	1x46	7x47	cck_off	0	0	Yes	No	No	No	8	7
80	3x48	I2x56	cck_off	50	0	No	No	No	Yes	6	5
81	1x35	2x65	cck_off	50	0	No	Yes	No	No	4	5
82	1x54	2x47	cck_off	0	0	No	No	No	No	7	9
83	7x32	7x36	cck_off	50	0	No	No	No	No	3	4
84	6x24	6x28	cck_off	0	0	No	No	No	No	4	5
85	1x30	1x34	cck_off	0	0	No	No	No	No	1	5
86	6x42	6x46	cck_off	0	0	No	No	No	No	6	5
87	5x40	6x56	cck_off	50	0	No	No	No	No	6	6
88	3x51	3x52	cck_off	0	0	Yes	No	No	No	8	6
89	2x38	I2x57	cck_off	50	0	No	No	No	Yes	7	7
90	1x54	2x44	cck_off	50	0	No	No	No	No	7	6
91	5x65	6x30	cck_off	50	0	No	No	No	No	9	8
92	1x48	1x49	cck_off	0	0	No	No	No	No	4	8
93	5x68	6x27	cck_off	0	0	No	No	No	No	7	4
94	2x58	2x62	cck_off	0	0	No	No	No	No	8	5
95	6x32	7x56	cck_off	50	0	No	No	No	No	8	7
96	6x33	6x37	cck_off	0	0	No	No	No	No	9	8
97	2x41	4x46	cck_off	0	0	No	No	No	No	5	7
98	1x57	I1x50	cck_off	0	0	No	No	No	No	7	8
99	8x47	8x48	cck_off	50	0	No	No	No	No	9	6
100	7x31	7x33	cck_off	0	0	No	No	No	No	3	4
101	6x54	Lig	cck_off	0	0	No	No	Yes	Yes	5	0
102	5x44	5x47	cck_off	0	0	No	No	No	No	7	8
103	1x49	1x52	cck_off	0	0	No	No	No	Yes	8	7
104	5x34	5x38	cck_off	0	0	No	No	No	No	2	4
105	5x62	6x38	cck_off	0	0	No	No	No	No	6	7
106	6x49	6x53	cck_off	0	0	No	No	No	No	6	6
107	5x37	6x59	cck_off	0	0	No	No	No	No	4	6
108	3x21	E1x52	cck_off	0	0	No	No	Yes	Yes	7	6
109	1x56	1x60	cck_off	0	0	No	No	No	No	8	6
110	5x41	5x45	cck_off	0	0	No	No	No	No	6	3
111	7x54	7x55	cck_off	0	0	No	Yes	No	Yes	8	6
112	1x43	1x44	cck_off	0	0	Yes	No	No	No	5	4
113	7x47	7x51	cck_off	0	0	No	No	No	No	7	6
114	4x38	I2x55	cck_off	0	0	No	No	No	No	8	5
115	4x51	4x52	cck_off	0	0	No	No	No	No	4	5
116	1x36	1x40	cck_off	0	0	No	No	No	No	5	4
117	1x40	1x41	cck_off	0	0	No	No	No	No	4	4
118	4x52	4x55	cck_off	0	0	No	No	No	No	5	5
119	5x33	E3	cck_off	0	0	No	No	Yes	Yes	2	3
120	2x41	4x43	cck_off	0	0	No	No	No	No	5	5
121	5x48	5x52	cck_off	0	0	No	No	No	No	6	4
122	6x29	6x32	cck_off	0	0	No	No	No	No	6	8
123	5x60	5x63	cck_off	0	0	No	No	No	No	5	4
124	I2x54	I2x55	cck_off	0	0	No	No	No	No	6	5
125	3x32	Lig	Shared	100	100	No	No	Yes	Yes	7	0
126	4x61	Lig	Shared	100	100	Yes	Yes	Yes	Yes	7	0
127	6x52	Lig	Shared	100	100	Yes	No	Yes	Yes	7	0
128	6x55	Lig	Shared	100	100	No	No	Yes	Yes	7	0
129	6x58	Lig	Shared	100	100	No	No	Yes	Yes	4	0
130	E3	Lig	Shared	100	100	Yes	Yes	Yes	Yes	3	0
131	7x34	Lig	Shared	100	100	No	Yes	Yes	Yes	5	0
132	1x30	1x31	Shared	100	100	No	No	Yes	No	1	1
133	1x31	7x32	Shared	100	50	Yes	No	No	No	1	3
134	1x35	7x35	Shared	100	100	No	Yes	No	No	4	5
135	1x36	2x65	Shared	100	100	No	No	No	No	5	5
136	1x39	2x61	Shared	100	100	No	No	No	No	7	6
137	1x39	7x39	Shared	100	100	No	No	No	No	7	7
138	1x42	7x39	Shared	100	100	No	No	No	No	7	7
139	1x43	1x47	Shared	100	100	Yes	No	No	No	5	6
140	1x43	2x57	Shared	100	100	Yes	No	No	Yes	5	7
141	1x45	7x47	Shared	100	16.6667	No	No	No	No	5	7
142	1x46	1x50	Shared	100	100	Yes	No	Yes	Yes	8	9
143	1x46	2x54	Shared	100	100	Yes	No	No	No	8	7
144	1x50	2x50	Shared	100	100	Yes	Yes	No	Yes	9	9
145	1x50	7x50	Shared	100	100	Yes	Yes	No	No	9	9
146	1x51	2x51	Shared	100	50	No	No	No	Yes	4	7
147	1x57	2x44	Shared	100	100	No	No	No	No	7	6
148	1x60	I1x50	Shared	100	100	No	No	No	No	6	8
149	I1x48	I1x51	Shared	100	100	No	No	No	No	7	8
150	2x37	2x40	Shared	100	100	No	No	No	No	7	9
151	2x41	4x39	Shared	100	16.6667	No	No	No	No	5	4
152	2x42	3x45	Shared	100	100	Yes	Yes	No	No	8	8
153	2x42	3x46	Shared	100	100	Yes	Yes	No	No	8	9
154	2x42	4x46	Shared	100	100	Yes	Yes	No	No	8	7
155	2x43	7x53	Shared	100	100	No	No	No	Yes	8	9
156	2x45	3x42	Shared	100	100	No	No	No	No	9	8
157	2x45	4x46	Shared	100	100	No	No	No	No	9	7
158	2x45	4x50	Shared	100	100	No	No	Yes	No	9	9
159	2x46	7x49	Shared	100	100	No	No	Yes	No	9	9
160	2x49	3x38	Shared	100	100	No	No	Yes	No	8	8
161	2x49	3x39	Shared	100	66.6667	No	No	No	No	8	9
162	2x50	7x46	Shared	100	100	No	Yes	No	No	9	9
163	2x51	2x55	Shared	100	0	No	Yes	No	No	7	5
164	2x52	3x31	Shared	100	100	No	No	Yes	No	7	5
165	2x53	3x35	Shared	100	100	Yes	No	No	No	8	6
166	2x551	3x31	Shared	100	100	No	No	Yes	No	5	5
167	2x56	7x42	Shared	100	100	No	No	Yes	Yes	7	7
168	2x57	7x42	Shared	100	100	No	Yes	Yes	Yes	7	7
169	2x59	E1x52	Shared	100	100	No	No	Yes	Yes	6	6
170	2x59	3x28	Shared	100	100	No	No	No	No	6	6
171	2x60	7x38	Shared	100	100	No	No	No	Yes	7	6
172	2x60	7x42	Shared	100	100	No	No	Yes	Yes	7	7
173	2x61	2x65	Shared	100	100	No	No	No	No	6	5
174	2x62	2x63	Shared	100	0	No	No	No	No	5	5
175	2x63	E1x50	Shared	100	100	No	No	Yes	Yes	5	8
176	2x67	E2	Shared	100	50	No	No	Yes	Yes	4	3
177	E1x49	E1x51	Shared	100	50	No	No	No	No	4	4
178	E1x50	E1x52	Shared	100	100	Yes	Yes	Yes	Yes	8	6
179	3x25	E1x50	Shared	100	100	No	No	Yes	Yes	9	8
180	E1x50	E2x50	Shared	100	100	Yes	Yes	No	No	8	9
181	3x24	E1x52	Shared	100	100	No	No	Yes	Yes	5	6
182	3x22	E2	Shared	100	100	No	No	Yes	Yes	4	3
183	3x25	E2x50	Shared	100	100	No	No	No	No	9	9
184	3x29	4x65	Shared	100	100	No	No	No	No	6	6
185	3x30	4x54	Shared	100	100	No	No	No	No	6	4
186	3x30	4x62	Shared	100	100	No	No	No	No	6	6
187	3x34	4x54	Shared	100	100	No	No	No	No	6	4
188	3x36	6x48	Shared	100	100	No	No	Yes	Yes	7	8
189	3x37	4x53	Shared	100	100	No	No	No	No	7	8
190	3x38	4x50	Shared	100	100	Yes	No	Yes	No	8	9
191	3x38	4x53	Shared	100	100	Yes	No	No	No	8	8
192	3x47	5x54	Shared	100	100	No	No	No	No	9	8
193	3x47	5x58	Shared	100	100	No	No	Yes	Yes	9	9
194	3x51	3x55	Shared	100	100	Yes	No	No	No	8	7
195	3x51	3x56	Shared	100	100	Yes	No	Yes	Yes	8	6
196	3x51	5x60	Shared	100	100	Yes	No	No	No	8	5
197	3x54	5x61	Shared	100	16.6667	No	No	No	No	9	9
198	3x56	I2x52	Shared	100	100	Yes	Yes	No	No	6	5
199	4x41	I2x56	Shared	100	100	Yes	Yes	No	Yes	7	5
200	4x41	4x45	Shared	100	100	Yes	Yes	No	No	7	6
201	4x57	4x61	Shared	100	66.6667	No	No	Yes	Yes	8	7
202	4x59	4x60	Shared	100	100	No	No	No	No	4	8
203	4x60	5x39	Shared	100	100	No	No	Yes	Yes	8	8
204	4x61	E2x52	Shared	100	100	Yes	Yes	Yes	Yes	7	5
205	4x61	5x39	Shared	100	100	Yes	Yes	Yes	Yes	7	8
206	4x63	4x64	Shared	100	100	No	No	No	No	5	5
207	4x64	E2	Shared	100	100	No	No	Yes	Yes	5	3
208	4x65	E2x52	Shared	100	100	No	No	Yes	Yes	6	5
209	E2	E2	Shared	100	100	Yes	Yes	Yes	Yes	3	3
210	E2	E2x51	Shared	100	100	Yes	Yes	No	No	3	4
211	E2	E2x52	Shared	100	100	Yes	Yes	Yes	Yes	3	5
212	5x36	E2	Shared	100	100	No	No	Yes	Yes	5	3
213	5x35	E2	Shared	100	100	No	No	Yes	Yes	4	3
214	5x32	5x35	Shared	100	50	No	No	No	No	5	4
215	5x36	5x40	Shared	100	100	No	No	No	No	5	6
216	5x37	6x60	Shared	100	100	No	No	No	No	4	5
217	5x39	5x42	Shared	100	50	Yes	Yes	No	No	8	5
218	5x39	5x43	Shared	100	100	Yes	Yes	No	No	8	7
219	5x42	5x46	Shared	100	100	No	No	No	No	5	5
220	5x47	6x45	Shared	100	100	No	No	Yes	No	8	6
221	5x51	6x45	Shared	100	0	No	No	Yes	No	6	6
222	5x58	6x37	Shared	100	100	Yes	Yes	No	No	9	8
223	5x69	6x27	Shared	100	50	No	No	No	No	5	4
224	6x28	6x31	Shared	100	50	No	No	No	No	5	6
225	6x36	7x56	Shared	100	50	No	No	No	No	9	7
226	6x40	7x52	Shared	100	100	No	No	No	Yes	9	9
227	6x43	7x48	Shared	100	100	No	No	No	No	6	7
228	6x44	6x48	Shared	100	100	Yes	No	Yes	Yes	9	8
229	6x47	7x45	Shared	100	100	No	No	No	No	8	9
230	6x48	6x52	Shared	100	100	Yes	Yes	Yes	No	8	7
231	6x48	7x41	Shared	100	100	Yes	Yes	No	No	8	7
232	6x48	7x45	Shared	100	100	Yes	Yes	No	No	8	9
233	6x50	7x37	Shared	100	50	No	Yes	No	Yes	9	6
234	6x51	7x37	Shared	100	100	No	No	No	Yes	7	6
235	6x51	7x41	Shared	100	100	No	No	No	No	7	7
236	6x57	E3	Shared	100	100	No	No	Yes	Yes	5	3
237	6x58	E3	Shared	100	100	No	No	Yes	Yes	4	3
238	6x61	E3	Shared	100	100	No	No	Yes	Yes	4	3
239	E3	E3	Shared	100	100	Yes	Yes	Yes	Yes	3	3
240	7x33	E3	Shared	100	100	No	No	Yes	Yes	4	3
241	7x34	7x37	Shared	100	100	No	Yes	No	Yes	5	6
242	E1x51	E1x52	Shared	100	100	No	No	Yes	Yes	4	6
243	5x40	6x59	Shared	50	100	No	No	No	No	6	6
244	3x33	4x57	Shared	0	100	No	No	No	No	6	8
245	1x38	7x39	Shared	50	100	No	No	No	No	5	7
246	4x38	4x41	Shared	50	0	No	No	Yes	Yes	8	7
247	3x47	5x57	Shared	0	0	No	No	No	No	9	6
248	5x49	5x50	Shared	0	16.6667	No	No	No	Yes	6	9
249	6x50	7x40	Shared	0	0	No	Yes	No	No	9	8
250	3x27	3x31	Shared	50	0	No	No	Yes	No	4	5
251	3x44	5x53	Shared	50	0	No	No	No	No	7	7
252	5x41	6x60	Shared	50	0	No	No	No	No	6	5
253	3x55	5x64	Shared	0	100	No	No	No	No	7	6
254	6x39	6x43	Shared	0	50	No	No	No	No	7	6
255	4x56	4x57	Shared	50	66.6667	No	No	No	No	6	8
256	2x42	4x42	Shared	0	100	Yes	Yes	No	No	8	7
257	1x50	2x51	Shared	50	100	Yes	Yes	No	Yes	9	7
258	1x53	2x47	Shared	0	16.6667	No	Yes	No	No	9	9
259	7x51	7x55	Shared	0	50	No	No	No	Yes	6	6
260	4x38	4x40	Shared	0	66.6667	No	No	No	No	8	5
261	5x56	5x60	Shared	0	0	No	No	No	No	5	5
262	5x32	5x34	Shared	0	50	No	No	No	No	5	2
263	1x54	1x58	Shared	0	0	No	No	No	No	7	3
264	6x32	6x35	Shared	50	50	No	No	No	No	8	7
265	5x45	5x48	Shared	50	50	No	No	No	No	3	6
266	5x59	5x62	Shared	0	16.6667	No	No	No	No	1	6
267	3x56	I2x50	Shared	0	0	Yes	Yes	No	No	6	8
268	6x38	6x42	Shared	0	0	No	No	No	No	7	6
269	7x56	8x47	Shared	0	50	No	No	No	No	7	9
270	1x37	1x38	Shared	0	0	No	No	No	No	4	5
271	I2x51	I2x52	Shared	0	0	No	No	No	No	7	5
272	1x35	7x32	cck_on	0	100	No	Yes	No	No	4	3
273	1x39	7x35	cck_on	0	100	No	No	No	No	7	5
274	1x42	2x57	cck_on	0	100	No	No	No	Yes	7	7
275	1x52	7x55	cck_on	0	100	No	Yes	No	Yes	7	6
276	1x53	7x54	cck_on	0	100	No	Yes	No	Yes	9	8
277	1x53	7x55	cck_on	0	100	No	Yes	No	Yes	9	6
278	1x53	8x50	cck_on	0	100	No	Yes	No	No	9	0
279	1x56	8x50	cck_on	0	100	No	No	No	No	8	0
280	1x56	8x57	cck_on	0	100	No	No	No	No	8	0
281	1x57	2x40	cck_on	0	100	No	No	No	No	7	9
282	1x60	I1x49	cck_on	0	100	No	No	No	No	6	6
283	2x37	2x39	cck_on	0	100	No	No	No	No	7	8
284	2x42	3x49	cck_on	0	100	Yes	Yes	No	Yes	8	9
285	2x43	7x54	cck_on	0	100	No	No	No	Yes	8	8
286	2x46	2x50	cck_on	0	100	No	No	No	Yes	9	9
287	2x50	7x49	cck_on	0	100	No	Yes	Yes	No	9	9
288	2x52	3x35	cck_on	0	100	No	No	No	No	7	6
289	2x54	2x57	cck_on	0	100	No	No	No	Yes	7	7
290	2x56	3x32	cck_on	0	100	No	No	No	No	7	7
291	2x63	Lig	cck_on	0	100	No	No	Yes	Yes	5	0
292	2x64	Lig	cck_on	0	100	No	No	Yes	Yes	6	0
293	2x66	E1x49	cck_on	0	100	No	No	No	No	4	4
294	3x22	3x26	cck_on	0	100	No	No	No	No	4	5
295	3x30	3x34	cck_on	0	100	No	No	No	No	6	6
296	3x36	Lig	cck_on	0	100	No	No	Yes	Yes	7	0
297	3x37	3x41	cck_on	0	100	No	No	No	No	7	6
298	3x37	5x461	cck_on	0	100	No	No	No	No	7	7
299	3x43	7x49	cck_on	0	100	No	No	Yes	No	8	9
300	3x43	7x53	cck_on	0	100	No	No	No	Yes	8	9
301	3x46	3x50	cck_on	0	100	No	No	Yes	No	9	9
302	3x48	5x53	cck_on	0	100	No	No	No	No	6	7
303	3x49	I2x56	cck_on	0	100	No	Yes	No	Yes	9	5
304	3x49	I2x57	cck_on	0	100	No	Yes	No	Yes	9	7
305	3x49	4x41	cck_on	0	100	No	Yes	Yes	Yes	9	7
306	3x50	5x58	cck_on	0	100	Yes	No	Yes	Yes	9	9
307	3x50	7x53	cck_on	0	100	Yes	No	No	Yes	9	9
308	3x53	I2x57	cck_on	0	100	No	No	No	Yes	8	7
309	I2x53	I2x57	cck_on	0	100	No	No	No	Yes	8	7
310	I2x56	I2x57	cck_on	0	100	No	Yes	No	Yes	5	7
311	4x50	4x54	cck_on	0	100	Yes	No	No	No	9	4
312	E2	Lig	cck_on	0	100	Yes	Yes	Yes	Yes	3	0
313	E2x50	Lig	cck_on	0	100	No	No	Yes	Yes	9	0
314	E2x51	Lig	cck_on	0	100	No	No	Yes	Yes	4	0
315	E2x52	Lig	cck_on	0	100	Yes	Yes	Yes	Yes	5	0
316	5x39	E2	cck_on	0	100	Yes	Yes	Yes	Yes	8	3
317	5x47	5x48	cck_on	0	100	No	No	No	No	8	6
318	5x47	6x49	cck_on	0	100	No	No	No	No	8	6
319	5x54	6x44	cck_on	0	100	No	No	Yes	No	8	9
320	5x58	6x41	cck_on	0	100	Yes	Yes	No	No	9	8
321	5x62	6x34	cck_on	0	100	No	No	No	No	6	8
322	5x66	5x70	cck_on	0	100	No	No	No	No	6	0
323	5x72	I3	cck_on	0	100	No	No	No	No	0	0
324	6x26	6x30	cck_on	0	100	No	No	No	No	4	8
325	6x28	6x32	cck_on	0	100	No	No	No	No	5	8
326	6x40	7x53	cck_on	0	100	No	No	No	Yes	9	9
327	6x57	6x61	cck_on	0	100	No	No	No	No	5	4
328	7x34	7x38	cck_on	0	100	No	Yes	No	Yes	5	6
329	7x38	7x42	cck_on	0	100	No	Yes	Yes	Yes	6	7
330	7x41	7x42	cck_on	0	100	No	No	Yes	Yes	7	7
331	7x52	7x53	cck_on	0	100	No	Yes	No	Yes	9	9
332	7x54	8x50	cck_on	0	100	No	Yes	No	No	8	0
333	8x48	8x51	cck_on	0	100	No	No	No	No	6	0
334	Lig	Lig	cck_on	0	100	Yes	Yes	Yes	Yes	0	0
335	4x39	I1x51	cck_on	0	100	No	No	No	No	4	8
336	7x38	Lig	cck_on	0	100	No	Yes	Yes	Yes	6	0
337	1x35	7x36	cck_on	0	50	No	Yes	No	No	4	4
338	3x52	I2x56	cck_on	0	50	No	No	No	Yes	6	5
339	5x33	5x37	cck_on	0	50	No	No	No	No	2	4
340	1x48	1x52	cck_on	0	50	No	No	No	Yes	4	7
341	2x53	2x56	cck_on	0	50	Yes	No	No	No	8	7
342	2x38	4x42	cck_on	0	50	No	No	No	No	7	7
343	1x32	1x35	cck_on	0	66.6667	No	No	No	Yes	4	4
344	2x58	2x59	cck_on	0	50	No	No	No	No	8	6
345	1x54	2x48	cck_on	0	50	No	No	No	No	7	6
346	1x52	8x54	cck_on	0	50	No	Yes	No	No	7	0
347	3x41	4x49	cck_on	0	50	No	No	No	No	6	7
348	5x34	5x37	cck_on	0	50	No	No	No	No	2	4
349	3x44	5x50	cck_on	0	33.3333	No	No	No	Yes	7	9
350	5x44	6x52	cck_on	0	16.6667	No	No	Yes	No	7	7
351	6x49	6x50	cck_on	0	50	No	No	No	Yes	6	9
352	1x49	7x55	cck_on	0	0	No	No	No	Yes	8	6
353	5x44	6x56	cck_on	0	50	No	No	No	No	7	6
354	8x48	8x52	cck_on	0	16.6667	No	No	No	Yes	6	0
355	1x60	8x57	cck_on	0	50	No	No	No	No	6	0
356	3x40	5x50	cck_on	0	16.6667	No	No	No	Yes	8	9
357	1x53	1x57	cck_on	0	0	No	Yes	No	No	9	7
358	5x63	5x64	cck_on	0	50	No	No	No	No	4	6
359	6x36	7x52	cck_on	0	50	No	No	No	Yes	9	9
360	5x61	6x37	cck_on	0	0	No	No	No	No	9	8
361	1x42	7x47	cck_on	0	50	No	No	No	No	7	7
362	1x54	2x51	cck_on	0	16.6667	No	No	No	Yes	7	7
363	1x32	NT	cck_on	0	50	No	No	No	No	4	5
364	1x41	1x45	cck_on	0	50	No	No	No	No	4	5
365	6x62	E3	cck_on	0	50	No	No	Yes	Yes	0	3
366	5x65	6x33	cck_on	0	0	No	No	No	No	9	9
367	3x52	3x56	cck_on	0	16.6667	No	No	Yes	Yes	6	6
368	2x38	4x39	cck_on	0	16.6667	No	No	No	No	7	4
369	5x61	5x65	cck_on	0	0	No	No	No	No	9	9
370	6x27	6x31	cck_on	0	16.6667	No	No	No	No	4	6
371	7x48	7x52	cck_on	0	0	No	No	No	Yes	7	9
372	1x52	1x55	cck_on	0	0	No	Yes	No	No	7	4
373	8x52	I1x49	cck_on	0	50	No	Yes	No	No	0	6
374	1x34	7x36	cck_on	0	0	No	No	No	No	5	4
375	5x55	6x45	cck_on	0	0	No	No	Yes	No	6	6
376	7x31	E3	cck_on	0	16.6667	No	No	Yes	Yes	3	3
377	I2x55	I2x56	cck_on	0	50	No	No	No	Yes	5	5
378	1x59	I1x48	cck_on	0	50	No	No	No	No	5	7
379	8x52	8x55	cck_on	0	16.6667	No	Yes	No	No	0	0
380	5x50	5x51	cck_on	0	0	No	Yes	No	No	9	6
381	5x65	6x34	cck_on	0	0	No	No	No	No	9	8
382	7x54	8x49	cck_on	0	33.3333	No	Yes	No	No	8	0
383	3x21	E1x50	cck_on	0	0	No	No	Yes	Yes	7	8
384	6x42	6x43	cck_on	0	0	No	No	No	No	6	6
385	5x52	5x55	cck_on	0	0	No	No	No	No	4	6
386	5x69	6x30	cck_on	0	0	No	No	No	No	5	8
387	6x47	7x43	cck_on	0	0	No	No	No	No	8	5
388	5x66	6x31	cck_on	0	16.6667	No	No	No	No	6	6
389	6x54	7x34	cck_on	0	0	No	No	No	Yes	5	5
390	6x54	7x37	cck_on	0	0	No	No	No	Yes	5	6
391	5x66	6x34	cck_on	0	16.6667	No	No	No	No	6	8
392	3x41	4x52	cck_on	0	0	No	No	No	No	6	5
393	8x52	8x56	cck_on	0	16.6667	No	Yes	No	No	0	0
394	8x53	8x56	cck_on	0	0	No	No	No	No	0	0
395	1x44	1x45	cck_on	0	16.6667	No	No	No	No	4	5
396	6x50	6x53	cck_on	0	0	No	Yes	No	No	9	6
397	5x64	5x67	cck_on	0	0	No	No	No	No	6	5
398	4x40	4x44	cck_on	0	16.6667	No	No	No	No	5	4
399	5x67	5x68	cck_on	0	0	No	No	No	No	5	7
400	5x35	5x38	cck_on	0	0	No	No	No	No	4	4
401	5x68	5x71	cck_on	0	0	No	No	No	No	7	0
402	6x23	6x26	cck_on	0	0	No	No	No	No	0	4
403	5x71	I3	cck_on	0	0	No	No	No	No	0	0
404	4x44	4x47	cck_on	0	16.6667	No	No	No	No	4	4
405	1x59	8x58	cck_on	0	0	No	No	No	No	5	0
406	6x26	6x29	cck_on	0	0	No	No	No	No	4	6
407	3x23	3x24	cck_on	0	0	No	No	No	No	3	5
408	4x47	4x51	cck_on	0	0	No	No	No	No	4	4
409	6x46	7x40	cck_on	0	0	No	No	No	No	5	8
410	4x55	4x56	cck_on	0	0	No	No	No	No	5	6

Orange: nodes, hubs and links specific of cck_off network

Green: nodes, hubs and links shared by both networks

Purple: nodes, hubs and links specific of cck_on network

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Owner: the name of the network the hub belong to or "Shared" if the corresponding hub is present in both networks.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub in the corresponding network.

Num Of Links: the number of links of the corresponding hub in the corresponding network.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Owner	cck_off Avg Int. Strength	cck_on Avg Int. Strength	cck_off Num Of Links	cck_on Num Of Links	ConSurf
1	1x31	cck_off	0	0	4	2	1
2	1x43	cck_off	0	0	4	2	5
3	1x46	cck_off	0	0	4	2	8
4	2x53	cck_off	50	0	4	2	8
5	3x31	cck_off	50	0	4	3	5
6	3x38	cck_off	100	0	5	3	8
7	3x50	cck_off	50	0	5	3	9
8	3x51	cck_off	0	0	5	3	8
9	4x50	cck_off	100	0	4	3	9
10	6x44	cck_off	100	0	5	2	9
11	6x45	cck_off	0	0	4	3	6
12	6x52	cck_off	100	16.6667	5	3	7
13	7x49	cck_off	50	50	4	3	9
14	Lig	Shared	100	100	11	17	0
15	1x50	Shared	50	50	4	4	9
16	2x42	Shared	100	100	5	5	8
17	E1x50	Shared	100	100	5	5	8
18	E1x52	Shared	100	50	7	4	6
19	3x56	Shared	0	0	4	4	6
20	4x41	Shared	0	0	4	4	7
21	4x61	Shared	100	50	5	4	7
22	E2	Shared	100	100	12	11	3
23	E2x52	Shared	100	50	4	4	5
24	5x39	Shared	100	33.3333	5	5	8
25	5x58	Shared	50	100	4	4	9
26	6x48	Shared	100	100	6	5	8
27	E3	Shared	100	100	9	9	3
28	7x42	Shared	100	100	5	5	7
29	1x35	cck_on	0	50	2	4	4
30	1x52	cck_on	0	0	1	4	7
31	1x53	cck_on	0	0	2	5	9
32	2x50	cck_on	0	50	2	4	9
33	2x51	cck_on	0	0	3	4	7
34	2x57	cck_on	0	0	3	4	7
35	3x49	cck_on	0	0	3	4	9
36	I2x56	cck_on	0	33.3333	2	5	5
37	I2x57	cck_on	0	0	1	4	7
38	5x50	cck_on	0	0	2	4	9
39	6x50	cck_on	0	0	2	4	9
40	7x34	cck_on	0	0	2	4	5
41	7x37	cck_on	0	0	3	4	6
42	7x38	cck_on	0	0	1	4	6
43	7x52	cck_on	0	0	1	4	9
44	7x53	cck_on	50	50	3	5	9
45	7x54	cck_on	0	0	1	4	8
46	7x55	cck_on	0	0	2	4	6
47	8x52	cck_on	0	0	0	4	0

Orange: nodes, hubs and links specific of cck_off network

Green: nodes, hubs and links shared by both networks

Purple: nodes, hubs and links specific of cck_on network

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Owner: the name of the network the link belong to or "Shared" if the corresponding link is present in both networks.

Recurrence: the relative Recurrence in the filtered pool of shortest paths.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Owner	cck_off Recurrence	cck_on Recurrence	cck_off Hub1?	cck_on Hub1?	cck_off Hub2?	cck_on Hub2?	ConSurf1	ConSurf2
1	2x60	7x42	cck_off	29.6899	0.771724	No	No	Yes	Yes	7	7
2	3x32	7x42	cck_off	28.1155	0	No	No	Yes	Yes	7	7
3	2x60	Lig	cck_off	29.7373	0	No	No	Yes	Yes	7	0
4	E3	Lig	cck_off	57.0751	8.54298	Yes	Yes	Yes	Yes	3	0
5	7x33	E3	cck_off	12.8604	1.57818	No	No	Yes	Yes	4	3
6	7x32	7x33	cck_off	10.0247	0	No	No	No	No	3	4
7	2x61	2x65	cck_off	17.6546	2.75891	No	No	No	No	6	5
8	1x39	2x61	cck_off	20.1394	4.12872	No	No	No	No	7	6
9	1x39	2x57	cck_off	34.8492	0	No	No	No	Yes	7	7
10	1x43	2x57	cck_off	51.5791	2.75891	Yes	No	No	Yes	5	7
11	1x43	2x54	cck_off	44.466	0	Yes	No	No	No	5	7
12	1x46	7x47	cck_off	12.6565	0	Yes	No	No	No	8	7
13	1x50	7x50	cck_off	10.1432	1.16144	Yes	Yes	No	No	9	9
14	1x53	7x53	cck_off	21.6332	0	No	Yes	No	Yes	9	9
15	7x49	7x53	cck_off	28.9217	0	Yes	No	No	Yes	9	9
16	2x46	7x49	cck_off	52.0011	0.482328	No	No	Yes	No	9	9
17	2x46	3x39	cck_off	53.7509	0	No	No	No	No	9	9
18	2x49	3x39	cck_off	20.1868	1.47013	No	No	No	No	8	9
19	2x49	3x35	cck_off	51.8399	0	No	No	No	No	8	6
20	2x53	3x35	cck_off	52.3947	6.8259	Yes	No	No	No	8	6
21	2x53	7x42	cck_off	35.4514	0	Yes	No	Yes	Yes	8	7
22	3x39	6x44	cck_off	47.6574	0	No	No	Yes	No	9	9
23	2x53	6x48	cck_off	23.1743	0	Yes	No	Yes	Yes	8	8
24	1x57	2x44	cck_off	11.9452	1.41225	No	No	No	No	7	6
25	1x54	2x44	cck_off	13.9036	0	No	No	No	No	7	6
26	1x54	2x47	cck_off	17.7921	0	No	No	No	No	7	9
27	1x53	2x47	cck_off	19.7221	1.41611	No	Yes	No	No	9	9
28	2x49	3x38	cck_off	58.052	2.93641	No	No	Yes	No	8	8
29	3x38	3x42	cck_off	25.4932	0	Yes	No	No	No	8	8
30	2x45	3x42	cck_off	24.872	1.47013	No	No	No	No	9	8
31	2x41	4x46	cck_off	14.5391	0	No	No	No	No	5	7
32	3x43	6x44	cck_off	64.8995	0	No	No	Yes	No	8	9
33	3x43	6x41	cck_off	63.7566	0	No	No	No	No	8	8
34	5x54	6x41	cck_off	62.6755	0	No	No	No	No	8	8
35	5x58	6x34	cck_off	57.464	0	Yes	Yes	No	No	9	8
36	3x50	6x34	cck_off	22.5958	0	Yes	No	No	No	9	8
37	2x42	4x45	cck_off	26.5838	0	Yes	Yes	No	No	8	6
38	2x52	4x50	cck_off	10.6648	0	No	No	Yes	No	7	9
39	4x60	5x39	cck_off	11.0774	5.79951	No	No	Yes	Yes	8	8
40	4x59	4x60	cck_off	10.091	3.00587	No	No	No	No	4	8
41	4x61	E2x52	cck_off	42.4459	0.451459	Yes	Yes	Yes	Yes	7	5
42	E2	E2x52	cck_off	64.6055	0.601945	Yes	Yes	Yes	Yes	3	5
43	E1x50	E2	cck_off	53.8742	0	Yes	Yes	Yes	Yes	8	3
44	6x58	Lig	cck_off	42.5218	1.35052	No	No	Yes	Yes	4	0
45	6x58	E2x51	cck_off	41.5497	0	No	No	No	No	4	4
46	E2	E2x51	cck_off	83.2227	0.0848896	Yes	Yes	No	No	3	4
47	E2x51	E3	cck_off	43.6077	0	No	No	Yes	Yes	4	3
48	E1x49	E2	cck_off	12.7324	0	No	No	Yes	Yes	4	3
49	3x40	6x44	cck_off	10.1337	0	No	No	Yes	No	8	9
50	3x50	3x54	cck_off	14.2119	0	Yes	No	No	No	9	9
51	5x61	6x34	cck_off	34.4414	0	No	No	No	No	9	8
52	3x51	5x61	cck_off	20.1394	0	Yes	No	No	No	8	9
53	3x54	5x61	cck_off	14.5343	1.20775	No	No	No	No	9	9
54	3x54	5x65	cck_off	25.0806	0	No	No	No	No	9	9
55	4x41	4x45	cck_off	23.6675	1.48171	Yes	Yes	No	No	7	6
56	5x36	E2	cck_off	43.2426	4.7654	No	No	Yes	Yes	5	3
57	5x32	5x35	cck_off	13.069	9.4652	No	No	No	No	5	4
58	5x36	5x40	cck_off	38.9605	3.18336	No	No	No	No	5	6
59	5x40	6x59	cck_off	30.368	1.59361	No	No	No	No	6	6
60	5x37	6x59	cck_off	26.0575	0	No	No	No	No	4	6
61	5x37	6x60	cck_off	21.7375	3.18336	No	No	No	No	4	5
62	5x43	6x52	cck_off	21.8086	0	No	No	Yes	No	7	7
63	5x65	6x31	cck_off	19.5135	0	No	No	No	No	9	6
64	6x28	6x31	cck_off	16.2841	4.12872	No	No	No	No	5	6
65	6x40	7x49	cck_off	17.242	0	No	No	Yes	No	9	9
66	6x36	6x40	cck_off	13.3488	0	No	No	No	No	9	9
67	4x38	4x41	cck_off	11.9072	7.34681	No	No	Yes	Yes	8	7
68	5x41	6x60	cck_off	17.408	1.59361	No	No	No	No	6	5
69	6x36	7x56	cck_off	11.3856	2.82451	No	No	No	No	9	7
70	5x41	5x45	cck_off	13.069	0	No	No	No	No	6	3
71	3x32	Lig	cck_off	61.7508	4.05155	No	No	Yes	Yes	7	0
72	2x53	3x32	cck_off	34.1142	0	Yes	No	No	No	8	7
73	3x46	6x37	cck_off	10.4088	0	No	No	No	No	9	8
74	5x39	5x43	cck_off	20.4619	3.00587	Yes	Yes	No	No	8	7
75	5x39	E2x52	cck_off	23.5584	0	Yes	Yes	Yes	Yes	8	5
76	2x57	7x42	Shared	85.864	30.1281	No	Yes	Yes	Yes	7	7
77	1x39	7x39	Shared	12.6565	17.0705	No	No	No	No	7	7
78	1x46	2x54	Shared	42.0761	19.8912	Yes	No	No	No	8	7
79	1x46	1x50	Shared	22.5673	19.7639	Yes	No	Yes	Yes	8	9
80	6x44	6x48	Shared	100	100	Yes	No	Yes	Yes	9	8
81	6x48	6x52	Shared	79.2631	39.9676	Yes	Yes	Yes	No	8	7
82	6x52	Lig	Shared	64.999	39.5701	Yes	No	Yes	Yes	7	0
83	2x45	4x46	Shared	53.6134	22.654	No	No	No	No	9	7
84	3x38	4x50	Shared	29.742	12.9843	Yes	No	Yes	No	8	9
85	2x45	4x50	Shared	31.2121	19.9298	No	No	Yes	No	9	9
86	3x47	5x54	Shared	63.7709	99.2283	No	No	No	No	9	8
87	3x47	5x58	Shared	61.7792	98.5337	No	No	Yes	Yes	9	9
88	2x42	4x46	Shared	39.8568	24.0045	Yes	Yes	No	No	8	7
89	2x42	3x46	Shared	11.3951	69.3124	Yes	Yes	No	No	8	9
90	4x61	Lig	Shared	51.2234	15.7702	Yes	Yes	Yes	Yes	7	0
91	E1x50	E1x52	Shared	29.2963	26.9447	Yes	Yes	Yes	Yes	8	6
92	2x63	E1x50	Shared	12.9315	16.4377	No	No	Yes	Yes	5	8
93	5x58	6x37	Shared	12.7987	25.3125	Yes	Yes	No	No	9	8
94	5x35	E2	Shared	17.408	12.5598	No	No	Yes	Yes	4	3
95	1x35	7x35	cck_on	5.0882	10.5302	No	Yes	No	No	4	5
96	1x39	7x35	cck_on	0	11.8537	No	No	No	No	7	5
97	1x42	7x39	cck_on	5.0882	20.9021	No	No	No	No	7	7
98	1x42	2x57	cck_on	0	27.1338	No	No	No	Yes	7	7
99	2x54	2x57	cck_on	0	20.1034	No	No	No	Yes	7	7
100	1x50	2x50	cck_on	2.57492	18.56	Yes	Yes	No	Yes	9	9
101	2x50	7x49	cck_on	0	17.522	No	Yes	Yes	No	9	9
102	3x43	7x49	cck_on	0	17.8423	No	No	Yes	No	8	9
103	3x43	7x53	cck_on	0	18.3284	No	No	No	Yes	8	9
104	2x43	7x53	cck_on	6.00341	37.4479	No	No	No	Yes	8	9
105	2x43	7x54	cck_on	0	36.4099	No	No	No	Yes	8	8
106	1x53	7x54	cck_on	0	18.5214	No	Yes	No	Yes	9	8
107	7x54	8x50	cck_on	0	15.4576	No	Yes	No	No	8	0
108	1x56	8x50	cck_on	0	14.7554	No	No	No	No	8	0
109	1x56	8x57	cck_on	0	13.6209	No	No	No	No	8	0
110	1x60	8x57	cck_on	0	12.4865	No	No	No	No	6	0
111	3x50	7x53	cck_on	0	53.0637	Yes	No	No	Yes	9	9
112	3x46	3x50	cck_on	0	70.3542	No	No	Yes	No	9	9
113	2x42	4x42	cck_on	2.93058	11.3559	Yes	Yes	No	No	8	7
114	7x41	7x42	cck_on	0	18.0429	No	No	Yes	Yes	7	7
115	6x48	7x41	cck_on	4.87007	25.4785	Yes	Yes	No	No	8	7
116	5x54	6x44	cck_on	0	99.5987	No	No	Yes	No	8	9
117	3x50	5x58	cck_on	0	89.4737	Yes	No	Yes	Yes	9	9
118	2x42	3x49	cck_on	0	38.4126	Yes	Yes	No	Yes	8	9
119	7x38	7x42	cck_on	0	16.8081	No	Yes	Yes	Yes	6	7
120	7x38	Lig	cck_on	0	13.702	No	Yes	Yes	Yes	6	0
121	2x63	Lig	cck_on	0	19.0963	No	No	Yes	Yes	5	0
122	E2x50	Lig	cck_on	0	19.2314	No	No	Yes	Yes	9	0
123	E1x50	E2x50	cck_on	4.13031	16.3876	Yes	Yes	No	No	8	9
124	E2	Lig	cck_on	0	32.6401	Yes	Yes	Yes	Yes	3	0
125	3x36	Lig	cck_on	0	38.4782	No	No	Yes	Yes	7	0
126	3x36	6x48	cck_on	1.14757	38.5823	No	No	Yes	Yes	7	8
127	7x34	7x37	cck_on	4.04495	10.2022	No	Yes	No	Yes	5	6
128	6x50	7x37	cck_on	7.24109	21.8707	No	Yes	No	Yes	9	6
129	6x49	6x50	cck_on	0	17.2094	No	No	No	Yes	6	9
130	5x47	6x49	cck_on	0	16.0248	No	No	No	No	8	6
131	5x47	6x45	cck_on	5.04078	12.4248	No	No	Yes	No	8	6
132	6x51	7x41	cck_on	4.39586	14.1766	No	No	No	No	7	7
133	6x51	7x37	cck_on	6.81904	13.8409	No	No	No	Yes	7	6
134	3x49	I2x56	cck_on	0	23.6611	No	Yes	No	Yes	9	5
135	3x52	I2x56	cck_on	0	21.8514	No	No	No	Yes	6	5
136	3x52	3x56	cck_on	0	20.4931	No	No	Yes	Yes	6	6
137	3x51	3x56	cck_on	8.55463	14.983	Yes	No	Yes	Yes	8	6
138	3x51	3x55	cck_on	3.44746	10.7694	Yes	No	No	No	8	7
139	5x61	6x37	cck_on	0	24.0624	No	No	No	No	9	8
140	5x61	5x65	cck_on	0	21.697	No	No	No	No	9	9
141	5x65	6x34	cck_on	0	19.3548	No	No	No	No	9	8
142	5x66	6x34	cck_on	0	15.5039	No	No	No	No	6	8
143	5x66	6x31	cck_on	0	13.0846	No	No	No	No	6	6
144	7x52	7x53	cck_on	0	12.2627	No	Yes	No	Yes	9	9

Here, those paths that begin and end at given residue pair(s) or that pass through a residue are used to generate a novel metapath. Such a path filtering is particularly recommended if some information on allosteric residues is available. The selection syntax for a residue pair ("Pairs") is C:C:c534,A:A:?600 (the lower-case "c" stands for cytosine and "?" indicates any non standard amino acid or nucleotide residue). Selection of more than one apical residue pair has the following syntax: C:C:c534,A:A:?600,C:C:c534,A:A:E41. Only one residue can be selected as a tail ("Tail"). For midway residue(s), each residue must be separated by a comma as well e.g. A:A:?600,A:A:E41.

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Node1	Node2	Owner	Net1LinkStrength	Net2LinkStrength	Comm1	Comm2	Node1Shell	Node2Shell
2x60	Lig	cck_off	5.035	0	0	1	1	0
3x29	Lig	cck_off	4.555	0	1	0	1	0
3x32	Lig	Shared	13.675	6.57	1	1	1	0
4x61	Lig	Shared	6.215	15.8967	1	1	1	0
6x51	Lig	cck_off	6.855	0	0	0	1	0
6x52	Lig	Shared	5.45	4.63333	1	1	1	0
6x55	Lig	Shared	16.355	11.2383	0	0	1	0
6x58	Lig	Shared	35.93	13.7567	1	1	1	0
E3	Lig	Shared	8.765	29.9883	1	1	1	0
7x34	Lig	Shared	19.33	21.7267	0	1	1	0
2x53	3x32	cck_off	4.24	0	1	0	2	1
2x53	6x48	cck_off	3.99	0	1	0	2	2
2x53	7x42	cck_off	5.275	0	1	0	2	2
2x56	7x42	Shared	4.03	10.0817	0	0	2	2
2x60	7x38	Shared	8.235	3.88667	0	1	1	1
2x60	7x42	Shared	11.05	7.94167	0	1	1	2
2x62	2x63	Shared	5.925	2.515	1	0	2	1
2x62	E1x52	cck_off	4.395	0	1	0	2	2
2x63	E1x50	Shared	8.67	4.09167	1	1	1	2
2x63	E1x52	cck_off	4.33	0	1	1	1	2
2x64	7x35	cck_off	3.725	0	0	0	1	2
2x67	E2	Shared	8.62	3.59	0	0	2	1
E1x49	E2	cck_off	8.235	0	1	0	2	1
E1x50	E1x52	Shared	4.825	9.29167	1	1	2	2
3x25	E1x50	Shared	4.19	6.055	1	1	2	2
E1x50	E2	cck_off	4.26	0	1	1	2	1
E1x50	E2x50	Shared	10.475	8.845	1	1	2	1
3x22	E2	Shared	3.75	4.63167	0	1	2	1
3x25	E2x50	Shared	7.28	6.97667	1	1	2	1
3x26	E2	cck_off	4.9	0	0	0	2	1
3x29	4x61	cck_off	6.865	0	1	0	1	1
3x29	4x65	Shared	7.195	4.79667	1	0	1	2
3x32	7x42	cck_off	7.185	0	1	1	1	2
3x36	6x48	Shared	7.97	5.71833	1	1	1	2
3x36	6x52	cck_off	7.21	0	1	1	1	1
4x57	4x61	Shared	4.19	3.59167	0	0	2	1
4x61	E2x52	Shared	20.115	8.69167	1	1	1	1
4x61	5x39	Shared	12.06	3.85833	1	1	1	2
4x64	E2	Shared	16.19	14.005	1	1	2	1
4x65	E2x52	Shared	4.62	5.40333	0	0	2	1
E2	E2	Shared	49.63	47.6633	1	1	1	1
E2	E2x51	Shared	9.965	11.5317	1	1	1	1
6x58	E2x51	cck_off	19.195	0	1	1	1	1
E2x51	E3	cck_off	4.65	0	1	1	1	1
E2	E2x52	Shared	6.7	4.10333	1	1	1	1
5x39	E2x52	cck_off	7.02	0	1	1	2	1
5x36	E2	Shared	10.65	3.83333	1	1	2	1
5x35	E2	Shared	11.215	7.73167	1	1	2	1
5x39	5x43	Shared	14.235	13.2867	1	1	2	2
5x43	6x52	cck_off	4.87	0	0	0	2	1
5x47	6x52	cck_off	11.785	0	0	0	2	1
6x48	6x52	Shared	4.51	6.72667	1	0	2	1
6x48	7x41	Shared	7.415	5.35333	1	0	2	2
6x51	7x37	Shared	3.68	3.745	0	0	1	2
6x51	7x41	Shared	6.19	3.70333	0	0	1	2
6x57	E3	Shared	22.475	15.3617	0	1	2	1
6x58	E3	Shared	8.6	11.2467	1	1	1	1
6x61	E3	Shared	13.32	3.67333	0	1	2	1
E3	E3	Shared	16.245	7.005	1	1	1	1
7x33	E3	Shared	3.9	3.82833	1	0	2	1
7x34	7x37	Shared	4.42	4.665	0	1	1	2
7x31	7x33	cck_off	2.03	0	0	0	2	2
6x54	Lig	cck_off	1.94	0	0	1	1	0
5x44	5x47	cck_off	1.83	0	0	0	2	2
5x33	E3	cck_off	0.725	0	0	0	2	1
2x56	3x32	cck_on	0	6.75	0	0	2	1
2x63	Lig	cck_on	0	4.43167	1	1	1	0
2x64	Lig	cck_on	0	4.95333	0	0	1	0
3x22	3x26	cck_on	0	4.295	0	1	2	2
3x36	Lig	cck_on	0	6.73	1	1	1	0
E2	Lig	cck_on	0	16.1717	1	1	1	0
E2x50	Lig	cck_on	0	5.15833	1	1	1	0
E2x51	Lig	cck_on	0	12.0583	1	1	1	0
E2x52	Lig	cck_on	0	12.9767	1	1	1	0
5x39	E2	cck_on	0	5.98167	1	1	2	1
6x57	6x61	cck_on	0	6.69833	0	1	2	2
7x34	7x38	cck_on	0	4.075	0	1	1	1
7x38	7x42	cck_on	0	9.63	0	1	1	2
7x41	7x42	cck_on	0	7.20667	0	0	2	2
7x38	Lig	cck_on	0	3.87667	0	1	1	0
2x53	2x56	cck_on	0	3.435	1	0	2	2
5x44	6x52	cck_on	0	3.19333	0	0	2	1
6x62	E3	cck_on	0	2.295	0	0	2	1
7x31	E3	cck_on	0	1.85833	0	0	2	1
6x54	7x34	cck_on	0	1.35	0	1	1	1
6x54	7x37	cck_on	0	1.35	0	1	1	2

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Difference Members
	Id	Description
	cck_off	ccka_off
	cck_on	ccka_on cckb_on

Network Difference
Value	cck_off	cck_on
I_min	3.665	3.62667
Number of Linked Nodes	243	262
Number of Specific Nodes	4 (1.65%)	23 (8.78%)
Number of Shared Nodes	239 (98.35%)	239 (91.22%)
Number of Links	271	286
Number of Specific Links	124 (45.76%)	139 (48.60%)
Number of Shared Links	147 (54.24%)	147 (51.40%)
Number of Hubs	28	34
Number of Specific Hubs	13 (46.43%)	19 (55.88%)
Number of Shared Hubs	15 (53.57%)	15 (44.12%)
Average % Shared Neighbours (Jaccard)	38.37
Average % Shared Neighbours (Otsuka)	47.55
Average % Shared Neighbours (Overlap Coefficient)	56.50
Average % Shared Cliques (k3-6)	77.00
Graphlets Similarity	0.477668

Paths Difference
Value	cck_off	cck_on
Number Of Nodes in MetaPath	85	66
Specific Nodes in MetaPath	48 (56.47%)	29 (43.94%)
Shared Nodes in MetaPath	239 (98.35%)	239 (98.35%)
Number Of Links MetaPath	94	69
Specific Links in MetaPath	75 (79.79%)	50 (72.46%)
Shared Links in MetaPath	147 (54.24%)	147 (54.24%)
Number of Shortest Paths	61775	50785
Length Of Smallest Path	3	3
Average Path Length	13.6745	14.1993
Length of Longest Path	29	32
Minimum Path Strength	0.725	0.450833
Average Path Strength	7.26101	5.88553
Maximum Path Strength	26.1425	22.3589
Minimum Path Correlation	0.7	0.7
Average Path Correlation	0.920326	0.917055
Maximum Path Correlation	0.99	0.99
Minimum % Of Corr. Nodes	4.54545	3.57143
Average % Of Corr. Nodes	45.5042	43.132
Maximum % Of Corr. Nodes	100	100
Minimum Path Hubs %	0	0
Average Path Hubs %	39.6782	37.778
Maximum Path Hubs %	100	100

Details about the values in these tables can be found in the corresponding documentation page .

You can download a compressed (zip) file with structure(s), 3D outputs (as PyMol and VMD scripts) and numerical data files (as csv and plain text files).

Download cck_off_on.zip<

You can click to copy the link of this page to easily come back here later

or use this QR code to link and share this page.

You can also read or download a guide explaining the meaning of all files and numerical data.