psnGPCR

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Orange: nodes, hubs and links specific of ccr_off network

Green: nodes, hubs and links shared by both networks

Purple: nodes, hubs and links specific of ccr_on network

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Owner: the name of the network the link belong to or "Shared" if the corresponding link is present in both networks.

Strength: the interaction strength between the two nodes or 0 if the link is not present.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Owner	ccr_off Int. Strength	ccr_on Int. Strength	ccr_off Hub1?	ccr_on Hub1?	ccr_off Hub2?	ccr_on Hub2?	ConSurf1	ConSurf2
1	1x24	1x27	ccr_off	100	0	No	No	No	No	3	1
2	1x24	Lig	ccr_off	100	0	No	No	Yes	Yes	3	0
3	1x35	7x39	ccr_off	100	0	No	Yes	No	No	6	6
4	1x38	1x42	ccr_off	100	0	No	No	No	No	6	7
5	1x39	2x60	ccr_off	100	0	Yes	Yes	No	No	8	7
6	1x56	8x53	ccr_off	100	0	No	No	Yes	No	7	5
7	1x60	CT	ccr_off	100	0	No	No	No	No	5	4
8	8x49	I1x48	ccr_off	100	0	No	No	No	No	6	5
9	2x41	I1x50	ccr_off	100	0	No	No	No	No	7	6
10	2x43	7x53	ccr_off	100	0	No	No	Yes	Yes	8	9
11	2x52	4x50	ccr_off	100	0	No	No	Yes	Yes	7	9
12	2x62	E1x51	ccr_off	100	0	No	No	No	No	5	3
13	2x63	E2	ccr_off	100	0	No	No	Yes	Yes	4	3
14	2x66	E1x49	ccr_off	100	0	No	No	No	No	4	3
15	E1x49	E1x51	ccr_off	100	0	No	No	No	No	3	3
16	3x37	5x46	ccr_off	100	0	Yes	Yes	No	No	7	4
17	3x40	5x50	ccr_off	100	0	No	No	Yes	Yes	7	9
18	3x40	6x44	ccr_off	100	0	No	No	No	Yes	7	9
19	3x43	6x40	ccr_off	100	0	No	No	No	No	8	8
20	3x50	6x33	ccr_off	100	0	No	No	No	No	9	8
21	3x51	5x61	ccr_off	100	0	Yes	Yes	No	No	8	8
22	I2x54	I2x55	ccr_off	100	0	No	No	No	No	4	3
23	4x61	5x39	ccr_off	100	0	No	No	No	No	4	5
24	E2	E2x52	ccr_off	100	0	Yes	Yes	No	No	3	4
25	5x31	E2	ccr_off	100	0	No	No	Yes	Yes	3	3
26	5x32	5x36	ccr_off	100	0	No	No	No	No	3	4
27	5x33	5x37	ccr_off	100	0	No	No	No	No	2	3
28	5x35	5x38	ccr_off	100	0	Yes	Yes	No	No	3	3
29	5x40	6x55	ccr_off	100	0	No	No	No	No	5	6
30	5x40	Lig	ccr_off	100	0	No	No	Yes	Yes	5	0
31	5x51	6x45	ccr_off	100	0	No	No	No	No	6	5
32	5x54	6x41	ccr_off	100	0	No	No	No	No	8	8
33	5x54	6x45	ccr_off	100	0	No	No	No	No	8	5
34	5x58	6x38	ccr_off	100	0	Yes	Yes	No	No	9	5
35	6x30	I3	ccr_off	100	0	No	Yes	No	No	7	3
36	6x29	6x32	ccr_off	100	0	No	No	No	No	6	7
37	6x29	6x33	ccr_off	100	0	No	No	No	No	6	8
38	6x36	7x53	ccr_off	100	0	No	No	Yes	Yes	8	9
39	6x38	6x42	ccr_off	100	0	No	No	No	No	5	5
40	6x40	7x53	ccr_off	100	0	No	No	Yes	Yes	8	9
41	6x48	6x51	ccr_off	100	0	Yes	Yes	No	No	9	7
42	6x50	7x37	ccr_off	100	0	No	No	No	No	9	7
43	6x62	E3	ccr_off	100	0	No	No	Yes	No	3	4
44	6x63	6x64	ccr_off	100	0	No	No	No	No	1	1
45	7x23	7x26	ccr_off	100	0	No	No	No	No	4	1
46	7x35	7x38	ccr_off	100	0	No	No	No	No	3	6
47	7x35	7x39	ccr_off	100	0	No	No	No	No	3	6
48	7x53	8x50	ccr_off	100	0	Yes	Yes	Yes	Yes	9	8
49	8x49	8x50	ccr_off	100	0	No	No	Yes	Yes	6	8
50	3x22	Lig	ccr_off	100	0	No	No	Yes	Yes	3	0
51	5x31	Lig	ccr_off	100	0	No	No	Yes	Yes	3	0
52	2x40	8x49	ccr_off	100	0	Yes	Yes	No	No	8	6
53	2x53	7x45	ccr_off	100	0	Yes	Yes	Yes	Yes	7	9
54	3x50	6x34	ccr_off	100	0	No	No	No	No	9	6
55	5x63	5x67	ccr_off	100	0	No	No	No	No	3	5
56	6x61	7x26	ccr_off	100	0	No	No	No	No	4	1
57	7x28	7x29	ccr_off	100	0	No	No	No	No	1	2
58	8x52	8x53	ccr_off	100	0	No	No	Yes	No	5	5
59	8x56	8x57	ccr_off	100	0	No	No	No	No	4	4
60	3x43	6x41	ccr_off	50	0	No	No	No	No	8	8
61	I1x49	I1x51	ccr_off	50	0	No	No	No	No	5	7
62	6x46	6x47	ccr_off	50	0	No	No	Yes	Yes	5	8
63	5x37	6x60	ccr_off	50	0	No	No	No	No	3	5
64	3x51	5x56	ccr_off	50	0	Yes	Yes	No	No	8	4
65	1x58	1x59	ccr_off	50	0	No	No	No	No	3	4
66	1x53	7x50	ccr_off	0	0	No	No	No	No	8	9
67	2x43	3x46	ccr_off	50	0	No	No	No	No	8	9
68	1x36	2x64	ccr_off	0	0	No	No	No	No	6	5
69	3x43	6x44	ccr_off	0	0	No	No	No	Yes	8	9
70	6x58	6x61	ccr_off	50	0	No	No	No	No	4	4
71	3x54	6x30	ccr_off	50	0	No	No	No	Yes	8	7
72	3x50	6x37	ccr_off	50	0	No	No	No	No	9	8
73	1x43	2x54	ccr_off	50	0	Yes	Yes	No	No	7	6
74	4x60	5x39	ccr_off	50	0	No	No	No	No	8	5
75	8x50	8x54	ccr_off	50	0	Yes	Yes	No	No	8	6
76	3x54	5x64	ccr_off	0	0	No	No	No	No	8	5
77	7x48	7x52	ccr_off	0	0	No	No	No	No	6	8
78	1x53	1x57	ccr_off	0	0	No	No	No	Yes	8	7
79	1x55	1x59	ccr_off	0	0	No	No	No	No	4	4
80	3x39	7x45	ccr_off	50	0	No	No	Yes	Yes	9	9
81	7x30	E3	ccr_off	50	0	No	Yes	Yes	No	5	4
82	2x40	I1x50	ccr_off	0	0	Yes	Yes	No	No	8	6
83	1x28	E2	ccr_off	50	0	No	No	Yes	Yes	1	3
84	5x65	6x31	ccr_off	50	0	No	No	No	No	8	5
85	1x31	Lig	ccr_off	50	0	No	No	Yes	Yes	5	0
86	6x39	7x52	ccr_off	50	0	No	No	No	No	5	8
87	1x54	1x58	ccr_off	0	0	No	No	No	No	7	3
88	7x23	7x25	ccr_off	50	0	No	No	No	No	4	1
89	3x24	3x27	ccr_off	0	0	No	No	No	No	6	5
90	1x25	1x26	ccr_off	50	0	No	No	No	No	3	1
91	2x44	2x48	ccr_off	0	0	No	Yes	No	No	6	6
92	3x21	E1x50	ccr_off	0	0	No	No	Yes	Yes	8	9
93	6x35	7x56	ccr_off	50	0	No	No	No	No	5	7
94	1x58	I1x49	ccr_off	0	0	No	No	No	No	3	5
95	4x55	4x59	ccr_off	0	0	No	No	No	No	4	4
96	8x57	8x58	ccr_off	0	0	No	No	No	No	4	5
97	7x48	7x51	ccr_off	0	0	No	No	No	No	6	6
98	7x36	7x40	ccr_off	0	0	No	No	No	No	5	8
99	4x44	4x45	ccr_off	0	0	No	No	No	No	1	6
100	4x41	I2x56	ccr_off	0	0	No	No	No	No	3	4
101	3x52	I2x56	ccr_off	0	0	No	No	No	No	5	4
102	5x55	5x59	ccr_off	0	0	No	No	No	No	4	3
103	8x56	8x59	ccr_off	0	0	No	No	No	No	4	3
104	1x45	7x47	ccr_off	0	0	No	No	No	No	5	8
105	1x25	1x29	ccr_off	0	0	No	No	No	No	3	2
106	5x66	5x67	ccr_off	0	0	No	No	No	No	4	5
107	6x65	E3	ccr_off	0	0	No	No	Yes	No	4	4
108	1x30	1x31	ccr_off	0	0	No	No	No	No	2	5
109	1x40	2x61	ccr_off	0	0	No	No	No	No	3	6
110	1x33	1x37	ccr_off	0	0	No	No	No	No	3	5
111	2x54	2x55	ccr_off	0	0	No	No	No	No	6	5
112	6x28	6x32	ccr_off	0	0	No	No	No	No	5	7
113	Lig	NT	Shared	100	100	Yes	Yes	No	Yes	0	4
114	1x35	1x39	Shared	100	100	No	Yes	Yes	Yes	6	8
115	1x35	2x64	Shared	100	100	No	Yes	No	No	6	5
116	1x39	7x39	Shared	100	100	Yes	Yes	No	No	8	6
117	1x39	7x42	Shared	100	100	Yes	Yes	Yes	Yes	8	8
118	1x41	1x45	Shared	100	30	No	No	No	No	5	5
119	1x43	2x57	Shared	100	100	Yes	Yes	No	No	7	7
120	1x43	2x58	Shared	100	100	Yes	Yes	No	No	7	9
121	1x46	2x54	Shared	100	20	No	No	No	No	8	6
122	1x49	7x50	Shared	100	0	No	No	No	No	8	9
123	1x50	2x50	Shared	100	100	No	No	No	Yes	9	9
124	1x50	2x51	Shared	100	100	No	No	No	No	9	7
125	1x50	7x50	Shared	100	100	No	No	No	No	9	9
126	1x56	8x50	Shared	100	100	No	No	Yes	Yes	7	8
127	1x60	8x53	Shared	100	100	No	No	Yes	No	5	5
128	2x40	I1x48	Shared	100	40	Yes	Yes	No	No	8	5
129	8x53	I1x48	Shared	100	100	Yes	No	No	No	5	5
130	2x44	I1x50	Shared	100	30	No	Yes	No	No	6	6
131	2x37	2x40	Shared	100	100	No	No	Yes	Yes	7	8
132	2x38	2x42	Shared	100	100	No	Yes	Yes	Yes	6	7
133	2x38	3x49	Shared	100	100	No	Yes	No	Yes	6	8
134	2x38	I2x57	Shared	100	100	No	Yes	Yes	Yes	6	6
135	2x42	3x45	Shared	100	100	Yes	Yes	No	No	7	6
136	2x42	4x45	Shared	100	100	Yes	Yes	No	No	7	6
137	2x45	3x42	Shared	100	100	No	No	Yes	Yes	9	7
138	2x45	4x46	Shared	100	100	No	No	No	No	9	7
139	2x45	4x50	Shared	100	100	No	No	Yes	Yes	9	9
140	2x46	7x49	Shared	100	100	No	No	No	Yes	9	9
141	2x49	3x38	Shared	100	100	No	No	No	No	8	7
142	2x50	7x46	Shared	100	100	No	Yes	No	No	9	8
143	2x50	7x49	Shared	100	100	No	Yes	No	Yes	9	9
144	2x53	3x32	Shared	100	100	Yes	Yes	Yes	Yes	7	7
145	2x53	7x46	Shared	100	100	Yes	Yes	No	No	7	8
146	2x56	2x60	Shared	100	60	No	No	No	No	7	7
147	2x57	7x42	Shared	100	100	No	No	Yes	Yes	7	8
148	2x59	E1x52	Shared	100	100	No	No	Yes	Yes	6	7
149	2x59	3x28	Shared	100	100	No	No	No	No	6	5
150	2x60	Lig	Shared	100	100	No	No	Yes	Yes	7	0
151	2x62	E1x52	Shared	100	30	No	No	Yes	Yes	5	7
152	2x63	E1x50	Shared	100	100	No	No	Yes	Yes	4	9
153	E1x49	E2	Shared	100	100	No	No	Yes	Yes	3	3
154	E1x50	E1x52	Shared	100	100	Yes	Yes	Yes	Yes	9	7
155	3x25	E1x50	Shared	100	100	No	No	Yes	Yes	9	9
156	E1x50	E2	Shared	100	100	Yes	Yes	Yes	Yes	9	3
157	E1x50	E2x50	Shared	100	100	Yes	Yes	No	No	9	9
158	3x22	3x26	Shared	100	100	No	No	No	No	3	7
159	3x22	E2	Shared	100	100	No	No	Yes	Yes	3	3
160	3x25	E2x50	Shared	100	100	No	No	No	No	9	9
161	3x29	4x65	Shared	100	100	No	No	No	No	5	5
162	3x29	Lig	Shared	100	100	No	No	Yes	Yes	5	0
163	3x30	4x62	Shared	100	100	No	No	No	No	5	4
164	3x32	3x33	Shared	100	100	Yes	Yes	No	No	7	5
165	3x32	7x42	Shared	100	100	Yes	Yes	Yes	Yes	7	8
166	3x32	Lig	Shared	100	100	Yes	Yes	Yes	Yes	7	0
167	3x33	4x57	Shared	100	20	No	No	No	No	5	7
168	3x33	4x61	Shared	100	100	No	No	No	No	5	4
169	3x34	4x57	Shared	100	100	No	No	No	No	5	7
170	3x36	3x37	Shared	100	100	No	Yes	Yes	Yes	7	7
171	3x36	5x43	Shared	100	100	No	Yes	No	No	7	5
172	3x36	6x48	Shared	100	100	No	Yes	Yes	Yes	7	9
173	3x37	3x41	Shared	100	100	Yes	Yes	Yes	Yes	7	5
174	3x38	4x50	Shared	100	100	No	No	Yes	Yes	7	9
175	3x41	4x49	Shared	100	100	Yes	Yes	No	No	5	6
176	3x41	5x46	Shared	100	100	Yes	Yes	No	No	5	4
177	3x42	4x46	Shared	100	100	Yes	Yes	No	No	7	7
178	3x42	4x49	Shared	100	100	Yes	Yes	No	No	7	6
179	3x42	4x50	Shared	100	100	Yes	Yes	Yes	Yes	7	9
180	3x44	5x50	Shared	100	100	No	No	Yes	Yes	7	9
181	3x44	5x53	Shared	100	100	No	No	No	No	7	6
182	3x45	4x49	Shared	100	100	No	No	No	No	6	6
183	3x49	I2x57	Shared	100	100	No	Yes	Yes	Yes	8	6
184	3x51	3x55	Shared	100	100	Yes	Yes	No	No	8	7
185	3x51	3x56	Shared	100	100	Yes	Yes	No	No	8	6
186	3x51	5x57	Shared	100	100	Yes	Yes	No	No	8	8
187	3x51	5x60	Shared	100	20	Yes	Yes	No	Yes	8	4
188	3x53	I2x57	Shared	100	100	No	No	Yes	Yes	8	6
189	3x54	5x61	Shared	100	100	No	No	No	No	8	8
190	3x55	3x56	Shared	100	100	No	No	No	No	7	6
191	I2x52	I2x56	Shared	100	100	No	No	No	No	5	4
192	4x63	4x64	Shared	100	100	No	No	No	No	3	5
193	4x64	E2	Shared	100	100	No	No	Yes	Yes	5	3
194	4x64	5x35	Shared	100	100	No	No	Yes	Yes	5	3
195	4x65	E2x52	Shared	100	100	No	No	No	No	5	4
196	E2	E2	Shared	100	100	Yes	Yes	Yes	Yes	3	3
197	E2	Lig	Shared	100	100	Yes	Yes	Yes	Yes	3	0
198	E2	E2x51	Shared	100	100	Yes	Yes	No	No	3	3
199	E2x51	Lig	Shared	100	100	No	No	Yes	Yes	3	0
200	E2x52	Lig	Shared	100	100	No	No	Yes	Yes	4	0
201	5x32	E2	Shared	100	100	No	No	Yes	Yes	3	3
202	5x35	E2	Shared	100	100	Yes	Yes	Yes	Yes	3	3
203	5x36	E2	Shared	100	40	No	No	Yes	Yes	4	3
204	5x32	Lig	Shared	100	100	No	No	Yes	Yes	3	0
205	5x34	5x35	Shared	100	100	No	No	Yes	Yes	1	3
206	5x40	6x59	Shared	100	100	No	No	No	Yes	5	5
207	5x44	6x56	Shared	100	100	No	No	No	No	5	5
208	5x47	6x52	Shared	100	100	No	No	No	No	8	8
209	5x49	5x50	Shared	100	100	No	No	Yes	Yes	6	9
210	5x62	5x66	Shared	100	0	No	No	No	No	4	4
211	6x32	8x48	Shared	100	20	No	No	No	No	7	5
212	6x36	7x56	Shared	100	100	No	No	No	No	8	7
213	6x44	6x48	Shared	100	100	No	Yes	Yes	Yes	9	9
214	6x47	7x45	Shared	100	100	Yes	Yes	Yes	Yes	8	9
215	6x47	7x48	Shared	100	20	Yes	Yes	No	No	8	6
216	6x48	7x41	Shared	100	100	Yes	Yes	No	No	9	8
217	6x48	7x45	Shared	100	100	Yes	Yes	Yes	Yes	9	9
218	6x51	6x55	Shared	100	100	No	No	No	No	7	6
219	6x51	7x37	Shared	100	100	No	No	No	No	7	7
220	6x54	7x37	Shared	100	100	No	No	No	No	5	7
221	6x56	6x60	Shared	100	100	No	No	No	No	5	5
222	6x59	6x60	Shared	100	40	No	Yes	No	No	5	5
223	6x61	Lig	Shared	100	100	No	No	Yes	Yes	4	0
224	7x26	7x29	Shared	100	30	No	No	No	No	1	2
225	7x31	Lig	Shared	100	100	No	No	Yes	Yes	4	0
226	7x34	Lig	Shared	100	100	No	No	Yes	Yes	5	0
227	7x35	Lig	Shared	100	100	No	No	Yes	Yes	3	0
228	8x57	CT	Shared	100	0	No	No	No	No	4	4
229	Lig	Lig	Shared	100	100	Yes	Yes	Yes	Yes	0	0
230	3x47	5x54	Shared	100	100	No	No	No	No	9	8
231	3x47	5x58	Shared	100	100	No	No	Yes	Yes	9	9
232	5x41	6x59	Shared	100	20	No	No	No	Yes	4	5
233	5x58	6x41	Shared	100	100	Yes	Yes	No	No	9	8
234	7x38	7x42	Shared	100	100	No	No	Yes	Yes	6	8
235	1x47	1x51	Shared	50	40	No	No	No	No	6	3
236	5x58	6x37	Shared	50	100	Yes	Yes	No	No	9	8
237	6x57	6x64	Shared	50	20	No	No	No	No	4	1
238	7x24	NT	Shared	50	100	No	No	No	Yes	6	4
239	3x37	5x42	Shared	50	100	Yes	Yes	No	No	7	3
240	5x58	5x61	Shared	50	100	Yes	Yes	No	No	9	8
241	2x42	4x42	Shared	50	100	Yes	Yes	No	No	7	7
242	2x39	3x49	Shared	50	100	No	No	No	Yes	8	8
243	6x49	6x50	Shared	50	40	No	Yes	No	No	6	9
244	E3	Lig	Shared	50	100	Yes	No	Yes	Yes	4	0
245	1x27	7x32	Shared	50	40	No	No	No	No	1	1
246	5x44	6x52	Shared	50	100	No	No	No	No	5	8
247	1x54	2x44	Shared	50	40	No	No	No	Yes	7	6
248	3x37	4x56	Shared	50	100	Yes	Yes	No	No	7	5
249	3x41	4x52	Shared	50	40	Yes	Yes	No	No	5	4
250	1x54	2x47	Shared	0	0	No	No	No	No	7	9
251	1x44	1x45	Shared	50	20	No	No	No	No	5	5
252	3x24	E1x52	Shared	0	100	No	No	Yes	Yes	6	7
253	5x461	5x50	Shared	50	40	No	No	Yes	Yes	6	9
254	2x53	3x35	Shared	50	60	Yes	Yes	No	No	7	8
255	4x38	4x40	Shared	50	60	No	No	No	No	6	4
256	5x65	6x34	Shared	50	20	No	No	No	No	8	6
257	1x36	1x37	Shared	50	100	No	No	No	No	6	5
258	1x43	1x47	Shared	50	100	Yes	Yes	No	No	7	6
259	1x32	2x64	Shared	50	20	No	No	No	No	4	5
260	4x38	4x41	Shared	0	20	No	No	No	No	6	3
261	I2x53	I2x57	Shared	0	20	No	No	Yes	Yes	5	6
262	7x56	8x47	Shared	0	0	No	No	No	No	7	8
263	6x43	6x47	Shared	0	100	No	No	Yes	Yes	6	8
264	1x36	2x65	Shared	0	40	No	No	No	No	6	4
265	8x55	8x59	Shared	50	0	No	No	No	No	4	3
266	7x27	Lig	Shared	50	100	No	No	Yes	Yes	3	0
267	3x27	3x31	Shared	50	40	No	No	No	Yes	5	5
268	5x41	5x45	Shared	50	20	No	No	No	No	4	5
269	1x39	2x61	Shared	0	100	Yes	Yes	No	No	8	6
270	6x54	7x33	Shared	0	20	No	No	No	No	5	6
271	4x59	4x60	Shared	0	20	No	No	No	No	4	8
272	6x47	7x40	Shared	50	100	Yes	Yes	No	No	8	8
273	1x42	7x43	Shared	0	0	No	No	No	No	7	5
274	3x34	4x54	Shared	0	60	No	No	No	No	5	4
275	4x57	4x62	Shared	50	0	No	No	No	No	7	4
276	5x52	5x56	Shared	50	40	No	No	No	No	4	4
277	5x45	5x48	Shared	50	10	No	No	No	No	5	4
278	6x57	7x30	Shared	0	100	No	No	No	Yes	4	5
279	6x47	7x43	Shared	0	40	Yes	Yes	No	No	8	5
280	1x46	7x47	Shared	0	20	No	No	No	No	8	8
281	8x48	8x51	Shared	0	100	No	No	No	No	5	8
282	1x48	1x49	Shared	0	10	No	No	No	No	3	8
283	3x38	4x53	Shared	0	20	No	No	No	No	7	7
284	3x52	I2x53	Shared	0	30	No	No	No	No	5	5
285	3x48	5x53	Shared	0	40	No	No	No	No	7	6
286	2x41	4x39	Shared	0	0	No	No	No	No	7	2
287	5x59	5x60	Shared	0	0	No	No	No	Yes	3	4
288	1x30	1x34	Shared	0	20	No	No	No	No	2	6
289	1x52	8x54	Shared	0	20	No	No	No	No	6	6
290	7x54	8x50	Shared	0	100	No	No	Yes	Yes	7	8
291	4x51	4x55	Shared	0	20	No	No	No	No	4	4
292	7x51	7x55	Shared	0	100	No	No	No	No	6	7
293	5x60	5x63	Shared	0	20	No	Yes	No	No	4	3
294	4x39	4x43	Shared	0	20	No	No	No	No	2	4
295	3x23	3x27	Shared	0	0	No	No	No	No	3	5
296	6x49	6x53	Shared	0	20	No	Yes	No	No	6	6
297	4x48	4x52	Shared	0	0	No	No	No	No	3	4
298	4x43	4x47	Shared	0	0	No	No	No	No	4	4
299	I2x52	I2x55	Shared	0	100	No	No	No	No	5	3
300	NT	NT	ccr_on	0	100	No	Yes	No	Yes	4	4
301	1x24	7x28	ccr_on	0	100	No	No	No	No	3	1
302	1x28	Lig	ccr_on	0	100	No	No	Yes	Yes	1	0
303	1x35	7x35	ccr_on	0	100	No	Yes	No	No	6	3
304	1x38	7x39	ccr_on	0	100	No	No	No	No	6	6
305	1x53	8x50	ccr_on	0	100	No	No	Yes	Yes	8	8
306	1x56	8x54	ccr_on	0	100	No	No	No	No	7	6
307	1x57	2x43	ccr_on	0	100	No	Yes	No	No	7	8
308	1x57	2x44	ccr_on	0	100	No	Yes	No	Yes	7	6
309	1x59	8x57	ccr_on	0	100	No	No	No	No	4	4
310	2x42	3x49	ccr_on	0	100	Yes	Yes	No	Yes	7	8
311	2x49	4x50	ccr_on	0	100	No	No	Yes	Yes	8	9
312	2x52	3x31	ccr_on	0	100	No	No	No	Yes	7	5
313	2x53	7x42	ccr_on	0	100	Yes	Yes	Yes	Yes	7	8
314	2x63	Lig	ccr_on	0	100	No	No	Yes	Yes	4	0
315	3x36	3x40	ccr_on	0	100	No	Yes	No	No	7	7
316	3x40	6x48	ccr_on	0	100	No	No	Yes	Yes	7	9
317	3x43	7x49	ccr_on	0	100	No	No	No	Yes	8	9
318	3x43	7x53	ccr_on	0	100	No	No	Yes	Yes	8	9
319	3x46	7x53	ccr_on	0	100	No	No	Yes	Yes	9	9
320	3x47	5x57	ccr_on	0	100	No	No	No	No	9	8
321	3x50	5x58	ccr_on	0	100	No	No	Yes	Yes	9	9
322	3x50	7x53	ccr_on	0	100	No	No	Yes	Yes	9	9
323	4x41	4x45	ccr_on	0	100	No	No	No	No	3	6
324	5x39	E2	ccr_on	0	100	No	No	Yes	Yes	5	3
325	5x31	5x35	ccr_on	0	100	No	No	Yes	Yes	3	3
326	5x38	5x42	ccr_on	0	100	No	No	No	No	3	3
327	5x47	5x51	ccr_on	0	100	No	No	No	No	8	6
328	5x47	6x49	ccr_on	0	100	No	No	No	Yes	8	6
329	5x50	6x44	ccr_on	0	100	Yes	Yes	No	Yes	9	9
330	5x54	6x44	ccr_on	0	100	No	No	No	Yes	8	9
331	5x62	6x34	ccr_on	0	100	No	No	No	No	4	6
332	5x62	6x37	ccr_on	0	100	No	No	No	No	4	8
333	6x29	I3	ccr_on	0	100	No	No	No	No	6	3
334	6x40	7x52	ccr_on	0	100	No	No	No	No	8	8
335	6x44	7x45	ccr_on	0	100	No	Yes	Yes	Yes	9	9
336	6x45	6x49	ccr_on	0	100	No	No	No	Yes	5	6
337	6x51	7x38	ccr_on	0	100	No	No	No	No	7	6
338	6x54	7x34	ccr_on	0	100	No	No	No	No	5	5
339	6x61	7x27	ccr_on	0	100	No	No	No	No	4	3
340	7x26	E3	ccr_on	0	100	No	No	Yes	No	1	4
341	7x24	Lig	ccr_on	0	100	No	No	Yes	Yes	6	0
342	7x38	Lig	ccr_on	0	100	No	No	Yes	Yes	6	0
343	7x45	7x49	ccr_on	0	100	Yes	Yes	No	Yes	9	9
344	7x49	7x50	ccr_on	0	100	No	Yes	No	No	9	9
345	7x49	7x53	ccr_on	0	100	No	Yes	Yes	Yes	9	9
346	7x52	7x53	ccr_on	0	100	No	No	Yes	Yes	8	9
347	7x55	8x50	ccr_on	0	100	No	No	Yes	Yes	7	8
348	1x27	7x28	ccr_on	0	100	No	No	No	No	1	1
349	2x54	2x57	ccr_on	0	100	No	No	No	No	6	7
350	2x60	3x32	ccr_on	0	100	No	No	Yes	Yes	7	7
351	5x54	5x58	ccr_on	0	100	No	No	Yes	Yes	8	9
352	6x32	6x35	ccr_on	0	100	No	No	No	No	7	5
353	3x24	3x28	ccr_on	0	100	No	No	No	No	6	5
354	E2x51	E2x52	ccr_on	0	100	No	No	No	No	3	4
355	6x62	Lig	ccr_on	0	100	No	No	Yes	Yes	3	0
356	2x62	2x66	ccr_on	0	100	No	No	No	No	5	4
357	1x25	Lig	ccr_on	0	20	No	No	Yes	Yes	3	0
358	5x33	Lig	ccr_on	0	40	No	No	Yes	Yes	2	0
359	2x50	3x39	ccr_on	0	40	No	Yes	No	No	9	9
360	6x62	6x63	ccr_on	0	20	No	No	No	No	3	1
361	2x37	I2x57	ccr_on	0	40	No	No	Yes	Yes	7	6
362	5x56	5x60	ccr_on	0	40	No	No	No	Yes	4	4
363	5x51	6x44	ccr_on	0	40	No	No	No	Yes	6	9
364	E1x51	E1x52	ccr_on	0	60	No	No	Yes	Yes	3	7
365	3x56	I2x52	ccr_on	0	30	No	No	No	No	6	5
366	2x56	3x31	ccr_on	0	60	No	No	No	Yes	7	5
367	5x37	6x59	ccr_on	0	40	No	No	No	Yes	3	5
368	6x34	6x38	ccr_on	0	10	No	No	No	No	6	5
369	1x57	8x50	ccr_on	0	20	No	Yes	Yes	Yes	7	8
370	1x30	7x32	ccr_on	0	40	No	No	No	No	2	1
371	2x40	I1x51	ccr_on	0	40	Yes	Yes	No	No	8	7
372	3x55	5x64	ccr_on	0	30	No	No	No	No	7	5
373	6x58	7x30	ccr_on	0	40	No	No	No	Yes	4	5
374	1x26	7x28	ccr_on	0	40	No	No	No	No	1	1
375	I1x49	I1x50	ccr_on	0	40	No	No	No	No	5	6
376	1x57	2x40	ccr_on	0	30	No	Yes	Yes	Yes	7	8
377	1x31	7x35	ccr_on	0	40	No	No	No	No	5	3
378	6x31	I3	ccr_on	0	20	No	No	No	No	5	3
379	6x61	7x30	ccr_on	0	20	No	No	No	Yes	4	5
380	2x48	4x50	ccr_on	0	20	No	No	Yes	Yes	6	9
381	6x32	6x36	ccr_on	0	20	No	No	No	No	7	8
382	5x65	6x33	ccr_on	0	0	No	No	No	No	8	8
383	1x27	NT	ccr_on	0	40	No	No	No	Yes	1	4
384	6x42	6x46	ccr_on	0	20	No	No	No	No	5	5
385	1x51	1x55	ccr_on	0	20	No	No	No	No	3	4
386	5x64	5x67	ccr_on	0	20	No	No	No	No	5	5
387	8x48	8x52	ccr_on	0	30	No	No	No	No	5	5
388	6x65	7x30	ccr_on	0	20	No	No	No	Yes	4	5
389	5x65	6x30	ccr_on	0	40	No	No	No	Yes	8	7
390	6x36	6x40	ccr_on	0	30	No	No	No	No	8	8
391	6x30	6x31	ccr_on	0	20	No	Yes	No	No	7	5
392	1x29	1x30	ccr_on	0	20	No	No	No	No	2	2
393	2x38	I2	ccr_on	0	20	No	Yes	No	No	6	0
394	7x23	Lig	ccr_on	0	20	No	No	Yes	Yes	4	0
395	5x68	6x30	ccr_on	0	30	No	No	No	Yes	0	7
396	1x35	1x36	ccr_on	0	20	No	Yes	No	No	6	6
397	2x41	I1x51	ccr_on	0	40	No	No	No	No	7	7
398	5x55	6x41	ccr_on	0	0	No	No	No	No	4	8
399	1x29	1x33	ccr_on	0	20	No	No	No	No	2	3
400	7x32	7x36	ccr_on	0	20	No	No	No	No	1	5
401	8x49	8x53	ccr_on	0	20	No	No	Yes	No	6	5
402	6x28	I3	ccr_on	0	20	No	No	No	No	5	3
403	4x60	5x42	ccr_on	0	20	No	No	No	No	8	3
404	2x55	3x31	ccr_on	0	20	No	No	No	Yes	5	5
405	2x67	Lig	ccr_on	0	20	No	No	Yes	Yes	0	0
406	1x58	2x44	ccr_on	0	0	No	No	No	Yes	3	6
407	6x45	6x46	ccr_on	0	20	No	No	No	No	5	5
408	1x60	8x57	ccr_on	0	10	No	No	No	No	5	4
409	3x21	3x24	ccr_on	0	0	No	No	No	No	8	6
410	1x59	8x60	ccr_on	0	20	No	No	No	No	4	0
411	4x40	4x44	ccr_on	0	0	No	No	No	No	4	1
412	7x25	7x29	ccr_on	0	0	No	No	No	No	1	2
413	1x43	1x44	ccr_on	0	10	Yes	Yes	No	No	7	5
414	8x52	8x56	ccr_on	0	0	No	No	No	No	5	4
415	6x39	6x43	ccr_on	0	0	No	No	No	No	5	6
416	1x40	1x41	ccr_on	0	0	No	No	No	No	3	5
417	6x27	6x30	ccr_on	0	0	No	No	No	Yes	0	7
418	4x47	4x51	ccr_on	0	0	No	No	No	No	4	4
419	1x59	8x61	ccr_on	0	0	No	No	No	No	4	0
420	8x55	8x56	ccr_on	0	0	No	No	No	No	4	4

Orange: nodes, hubs and links specific of ccr_off network

Green: nodes, hubs and links shared by both networks

Purple: nodes, hubs and links specific of ccr_on network

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Owner: the name of the network the hub belong to or "Shared" if the corresponding hub is present in both networks.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub in the corresponding network.

Num Of Links: the number of links of the corresponding hub in the corresponding network.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Owner	ccr_off Avg Int. Strength	ccr_on Avg Int. Strength	ccr_off Num Of Links	ccr_on Num Of Links	ConSurf
1	E3	ccr_off	50	40	4	2	4
2	8x53	ccr_off	50	0	4	3	5
3	1x39	Shared	50	20	5	4	8
4	1x43	Shared	50	0	4	4	7
5	2x40	Shared	0	0	4	4	8
6	2x42	Shared	50	100	4	5	7
7	2x53	Shared	50	90	4	4	7
8	E1x50	Shared	100	100	6	5	9
9	E1x52	Shared	50	40	4	5	7
10	3x32	Shared	50	30	4	5	7
11	3x37	Shared	50	60	5	4	7
12	3x41	Shared	0	20	4	4	5
13	3x42	Shared	100	80	4	4	7
14	3x51	Shared	100	20	6	4	8
15	I2x57	Shared	0	40	4	5	6
16	4x50	Shared	100	50	4	5	9
17	E2	Shared	100	100	15	12	3
18	5x35	Shared	50	40	4	4	3
19	5x50	Shared	0	20	4	4	9
20	5x58	Shared	0	100	5	6	9
21	6x47	Shared	0	20	6	5	8
22	6x48	Shared	100	80	5	5	9
23	7x42	Shared	50	90	4	5	8
24	7x45	Shared	100	80	4	4	9
25	7x53	Shared	100	90	4	5	9
26	8x50	Shared	50	80	5	5	8
27	Lig	Shared	100	100	21	25	0
28	NT	ccr_on	50	100	2	5	4
29	1x35	ccr_on	0	20	3	4	6
30	1x57	ccr_on	0	20	1	4	7
31	2x38	ccr_on	0	0	3	4	6
32	2x44	ccr_on	0	0	3	4	6
33	2x50	ccr_on	50	20	3	4	9
34	3x31	ccr_on	0	0	1	4	5
35	3x36	ccr_on	0	30	3	4	7
36	3x49	ccr_on	0	40	3	4	8
37	5x60	ccr_on	0	0	3	4	4
38	6x30	ccr_on	0	0	2	4	7
39	6x44	ccr_on	50	60	3	5	9
40	6x49	ccr_on	0	20	2	4	6
41	6x59	ccr_on	0	0	3	4	5
42	7x30	ccr_on	0	0	2	4	5
43	7x49	ccr_on	0	60	2	6	9

Orange: nodes, hubs and links specific of ccr_off network

Green: nodes, hubs and links shared by both networks

Purple: nodes, hubs and links specific of ccr_on network

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Owner: the name of the network the link belong to or "Shared" if the corresponding link is present in both networks.

Recurrence: the relative Recurrence in the filtered pool of shortest paths.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Owner	ccr_off Recurrence	ccr_on Recurrence	ccr_off Hub1?	ccr_on Hub1?	ccr_off Hub2?	ccr_on Hub2?	ConSurf1	ConSurf2
1	6x47	7x45	ccr_off	16.6884	8.35899	Yes	Yes	Yes	Yes	8	9
2	2x53	7x45	ccr_off	76.4585	0	Yes	Yes	Yes	Yes	7	9
3	3x32	7x42	ccr_off	24.6208	6.46072	Yes	Yes	Yes	Yes	7	8
4	1x56	8x50	ccr_off	13.8736	5.79009	No	No	Yes	Yes	7	8
5	7x53	8x50	ccr_off	45.073	0	Yes	Yes	Yes	Yes	9	8
6	6x40	7x53	ccr_off	53.4289	0	No	No	Yes	Yes	8	9
7	3x43	6x40	ccr_off	54.685	0	No	No	No	No	8	8
8	3x43	6x44	ccr_off	93.4493	0	No	No	No	Yes	8	9
9	6x48	6x51	ccr_off	51.0142	0	Yes	Yes	No	No	9	7
10	6x51	6x55	ccr_off	49.1253	1.32659	No	No	No	No	7	6
11	5x40	6x55	ccr_off	48.9997	0	No	No	No	No	5	6
12	5x40	Lig	ccr_off	48.1902	0	No	No	Yes	Yes	5	0
13	1x56	8x53	ccr_off	12.4546	0	No	No	Yes	No	7	5
14	8x49	8x50	ccr_off	26.105	0	No	No	Yes	Yes	6	8
15	2x40	I1x50	ccr_off	21.4246	0	Yes	Yes	No	No	8	6
16	2x40	8x49	ccr_off	23.253	0	Yes	Yes	No	No	8	6
17	2x44	I1x50	ccr_off	13.9806	4.01275	No	Yes	No	No	6	6
18	3x42	4x49	ccr_off	12.4267	9.55365	Yes	Yes	No	No	7	6
19	3x32	3x33	ccr_off	15.181	9.0516	Yes	Yes	No	No	7	5
20	3x40	6x44	ccr_off	10.9054	0	No	No	No	Yes	7	9
21	3x50	6x37	ccr_off	14.0225	0	No	No	No	No	9	8
22	5x58	6x41	ccr_off	45.1056	2.31604	Yes	Yes	No	No	9	8
23	3x43	6x41	ccr_off	51.5865	0	No	No	No	No	8	8
24	3x51	5x61	ccr_off	20.0149	0	Yes	Yes	No	No	8	8
25	5x58	5x61	ccr_off	26.7377	2.42231	Yes	Yes	No	No	9	8
26	3x51	5x60	ccr_off	10.9705	8.49824	Yes	Yes	No	Yes	8	4
27	3x52	I2x56	ccr_off	10.9054	0	No	No	No	No	5	4
28	3x52	I2x53	ccr_off	12.4267	2.00821	No	No	No	No	5	5
29	I2x53	I2x57	ccr_off	13.9388	3.85151	No	No	Yes	Yes	5	6
30	5x40	6x59	ccr_off	14.6832	1.21299	No	No	No	Yes	5	5
31	6x61	Lig	ccr_off	12.6221	7.82029	No	No	Yes	Yes	4	0
32	1x54	2x44	ccr_off	10.9379	4.01275	No	No	No	Yes	7	6
33	E3	Lig	ccr_off	11.6591	5.18543	Yes	No	Yes	Yes	4	0
34	2x53	3x32	Shared	74.4626	75.5863	Yes	Yes	Yes	Yes	7	7
35	3x32	Lig	Shared	56.1645	70.8333	Yes	Yes	Yes	Yes	7	0
36	1x43	2x57	Shared	13.9155	13.9475	Yes	Yes	No	No	7	7
37	2x57	7x42	Shared	15.1252	19.9575	No	No	Yes	Yes	7	8
38	2x50	7x46	Shared	12.4639	100	No	Yes	No	No	9	8
39	2x53	7x46	Shared	13.6596	99.6335	Yes	Yes	No	No	7	8
40	6x44	6x48	Shared	100	24.8351	No	Yes	Yes	Yes	9	9
41	6x48	7x45	Shared	77.8403	64.0575	Yes	Yes	Yes	Yes	9	9
42	1x60	8x53	Shared	10.0958	11.0048	No	No	Yes	No	5	5
43	2x38	2x42	Shared	21.3594	35.9169	No	Yes	Yes	Yes	6	7
44	2x42	3x45	Shared	27.1285	76.5281	Yes	Yes	No	No	7	6
45	3x45	4x49	Shared	28.5475	77.1108	No	No	No	No	6	6
46	3x41	4x49	Shared	40.8998	82.0251	Yes	Yes	No	No	5	6
47	3x37	3x41	Shared	44.7055	84.0186	Yes	Yes	Yes	Yes	7	5
48	3x36	3x37	Shared	49.986	86.7891	No	Yes	Yes	Yes	7	7
49	3x36	6x48	Shared	52.4984	87.2545	No	Yes	Yes	Yes	7	9
50	2x38	I2x57	Shared	16.8326	34.3961	No	Yes	Yes	Yes	6	6
51	E1x50	E1x52	Shared	14.7809	22.6546	Yes	Yes	Yes	Yes	9	7
52	E1x50	E2	Shared	21.6153	15.1862	Yes	Yes	Yes	Yes	9	3
53	E2	Lig	Shared	42.4165	27.2611	Yes	Yes	Yes	Yes	3	0
54	5x58	6x37	Shared	15.5253	16.1756	Yes	Yes	No	No	9	8
55	1x27	NT	ccr_on	0	13.0863	No	No	No	Yes	1	4
56	Lig	NT	ccr_on	3.20089	14.1271	Yes	Yes	No	Yes	0	4
57	1x39	7x42	ccr_on	9.38401	11.7597	Yes	Yes	Yes	Yes	8	8
58	2x50	7x49	ccr_on	2.56351	99.9524	No	Yes	No	Yes	9	9
59	1x57	8x50	ccr_on	0	15.4317	No	Yes	Yes	Yes	7	8
60	1x57	2x40	ccr_on	0	30.8634	No	Yes	Yes	Yes	7	8
61	2x37	2x40	ccr_on	1.58649	60.7153	No	No	Yes	Yes	7	8
62	2x37	I2x57	ccr_on	0	62.4634	No	No	Yes	Yes	7	6
63	7x45	7x49	ccr_on	0	87.0786	Yes	Yes	No	Yes	9	9
64	3x49	I2x57	ccr_on	0.0977017	34.6856	No	Yes	Yes	Yes	8	6
65	2x42	3x49	ccr_on	0	36.3127	Yes	Yes	No	Yes	7	8
66	1x57	2x44	ccr_on	0	11.9576	No	Yes	No	Yes	7	6
67	8x53	I1x48	ccr_on	0.828138	14.5119	Yes	No	No	No	5	5
68	2x40	I1x48	ccr_on	0.814181	16.4724	Yes	Yes	No	No	8	5
69	2x63	E1x50	ccr_on	0.0511771	14.7684	No	No	Yes	Yes	4	9
70	2x63	Lig	ccr_on	0	15.7505	No	No	Yes	Yes	4	0
71	7x49	7x53	ccr_on	0	32.3256	No	Yes	Yes	Yes	9	9
72	6x44	7x45	ccr_on	0	23.5745	No	Yes	Yes	Yes	9	9
73	3x47	5x54	ccr_on	1.83772	15.4977	No	No	No	No	9	8
74	5x54	6x44	ccr_on	0	26.7847	No	No	No	Yes	8	9
75	3x50	5x58	ccr_on	0	19.2612	No	No	Yes	Yes	9	9
76	3x50	7x53	ccr_on	0	19.5324	No	No	Yes	Yes	9	9
77	3x47	5x57	ccr_on	0	23.3399	No	No	No	No	9	8
78	3x51	5x57	ccr_on	1.59114	21.7202	Yes	Yes	No	No	8	8
79	5x44	6x52	ccr_on	2.7496	10.6824	No	No	No	No	5	8
80	5x47	6x52	ccr_on	1.37713	11.833	No	No	No	No	8	8
81	5x47	5x51	ccr_on	0	19.6826	No	No	No	No	8	6
82	5x51	6x44	ccr_on	0	20.7747	No	No	No	Yes	6	9
83	5x62	6x37	ccr_on	0	15.0542	No	No	No	No	4	8
84	5x62	6x34	ccr_on	0	12.7895	No	No	No	No	4	6
85	5x65	6x34	ccr_on	2.89848	10.4955	No	No	No	No	8	6
86	6x36	6x40	ccr_on	0	12.5257	No	No	No	No	8	8
87	6x40	7x52	ccr_on	0	13.4821	No	No	No	No	8	8
88	7x52	7x53	ccr_on	0	14.6255	No	No	Yes	Yes	8	9
89	2x40	I1x51	ccr_on	0	13.9255	Yes	Yes	No	No	8	7
90	2x41	I1x51	ccr_on	0	11.9576	No	No	No	No	7	7
91	2x53	7x42	ccr_on	0	23.2886	Yes	Yes	Yes	Yes	7	8
92	5x54	5x58	ccr_on	0	10.5981	No	No	Yes	Yes	8	9

Here, those paths that begin and end at given residue pair(s) or that pass through a residue are used to generate a novel metapath. Such a path filtering is particularly recommended if some information on allosteric residues is available. The selection syntax for a residue pair ("Pairs") is C:C:c534,A:A:?600 (the lower-case "c" stands for cytosine and "?" indicates any non standard amino acid or nucleotide residue). Selection of more than one apical residue pair has the following syntax: C:C:c534,A:A:?600,C:C:c534,A:A:E41. Only one residue can be selected as a tail ("Tail"). For midway residue(s), each residue must be separated by a comma as well e.g. A:A:?600,A:A:E41.

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Node1	Node2	Owner	Net1LinkStrength	Net2LinkStrength	Comm1	Comm2	Node1Shell	Node2Shell
Lig	NT	Shared	19.49	62.51	1	1	0	1
1x24	1x27	ccr_off	5.31	0	1	0	1	2
1x24	Lig	ccr_off	4.935	0	1	0	1	0
1x35	1x39	Shared	12.31	8.612	1	0	2	2
1x35	7x39	ccr_off	4.375	0	1	0	2	2
1x39	2x60	ccr_off	3.785	0	1	0	2	1
1x39	7x39	Shared	8.04	4.046	1	0	2	2
1x39	7x42	Shared	9.765	6.049	1	0	2	2
2x53	3x32	Shared	7.225	9.697	0	1	2	1
2x56	2x60	Shared	4.85	3.154	0	0	2	1
2x60	Lig	Shared	14.185	17.186	1	1	1	0
2x63	E1x50	Shared	7.235	8.439	1	1	1	2
2x63	E2	ccr_off	4.75	0	1	1	1	1
E1x49	E2	Shared	11.63	5.215	1	0	2	1
E1x50	E2	Shared	4.125	5.249	1	1	2	1
3x22	3x26	Shared	6.12	4.798	1	1	1	2
3x22	E2	Shared	13.445	5.172	1	1	1	1
3x29	4x65	Shared	14.06	10.083	1	1	1	2
3x29	Lig	Shared	4.37	4.415	1	1	1	0
3x32	3x33	Shared	8.595	5.542	1	1	1	2
3x32	7x42	Shared	3.775	4.407	1	1	1	2
3x32	Lig	Shared	6.955	7.224	1	1	1	0
4x64	E2	Shared	15.575	11.758	1	1	2	1
4x64	5x35	Shared	9.52	10.924	1	1	2	2
4x65	E2x52	Shared	4.615	3.232	0	0	2	1
E2	E2	Shared	49.57	56.808	1	1	1	1
E2	Lig	Shared	89.66	59.785	1	1	1	0
E2	E2x51	Shared	10.955	3.599	1	1	1	1
E2x51	Lig	Shared	9.025	9.804	1	1	1	0
E2	E2x52	ccr_off	6.485	0	1	1	1	1
E2x52	Lig	Shared	8.37	3.698	1	1	1	0
5x32	E2	Shared	4.88	3.588	1	1	1	1
5x35	E2	Shared	5.56	8.873	1	1	2	1
5x36	E2	Shared	10.265	3.138	1	0	2	1
5x31	E2	ccr_off	8.35	0	1	0	1	1
5x32	5x36	ccr_off	4.18	0	1	1	1	2
5x32	Lig	Shared	11.885	8.401	1	1	1	0
5x33	5x37	ccr_off	5.94	0	0	0	1	2
5x40	6x55	ccr_off	8.39	0	1	0	1	2
5x40	6x59	Shared	9.3	7.186	1	0	1	2
5x40	Lig	ccr_off	3.92	0	1	0	1	0
6x51	6x55	Shared	6.47	9.955	0	0	2	2
6x61	Lig	Shared	5.64	4.558	1	1	1	0
6x62	E3	ccr_off	6.575	0	0	1	1	1
7x23	7x26	ccr_off	4.47	0	0	0	1	2
7x31	Lig	Shared	5.61	5.44	0	0	1	0
7x34	Lig	Shared	3.94	6.511	0	1	1	0
7x35	7x38	ccr_off	5.735	0	1	1	1	1
7x35	7x39	ccr_off	4.16	0	1	1	1	2
7x35	Lig	Shared	8.925	3.587	1	1	1	0
3x22	Lig	ccr_off	5.06	0	1	1	1	0
5x31	Lig	ccr_off	3.945	0	1	0	1	0
6x61	7x26	ccr_off	5.305	0	1	1	1	2
7x38	7x42	Shared	4.08	7.439	0	1	1	2
7x24	NT	Shared	3.64	5.46	0	1	1	1
E3	Lig	Shared	3.585	6.01	1	1	1	0
6x58	6x61	ccr_off	3.3	0	0	0	2	1
7x30	E3	ccr_off	2.77	0	0	0	2	1
7x27	Lig	Shared	2.64	4.344	0	1	1	0
1x28	E2	ccr_off	2.62	0	0	0	1	1
1x31	Lig	ccr_off	2.365	0	1	0	1	0
7x23	7x25	ccr_off	2.235	0	0	0	1	2
1x25	1x26	ccr_off	2.125	0	0	0	1	2
1x25	1x29	ccr_off	1.37	0	0	0	1	2
6x65	E3	ccr_off	0.85	0	0	0	2	1
1x30	1x31	ccr_off	0.85	0	0	0	2	1
NT	NT	ccr_on	0	11.183	1	1	1	1
1x24	7x28	ccr_on	0	3.518	1	0	1	2
1x28	Lig	ccr_on	0	7.521	0	0	1	0
1x35	7x35	ccr_on	0	4.56	1	0	2	1
2x53	7x42	ccr_on	0	6.691	0	1	2	2
2x63	Lig	ccr_on	0	6.64	1	1	1	0
5x39	E2	ccr_on	0	5.095	0	0	2	1
5x31	5x35	ccr_on	0	3.643	1	0	1	2
6x51	7x38	ccr_on	0	8.14	0	0	2	1
6x54	7x34	ccr_on	0	3.893	0	0	2	1
6x61	7x27	ccr_on	0	4.126	1	1	1	1
7x26	E3	ccr_on	0	3.7	0	0	2	1
7x24	Lig	ccr_on	0	3.346	0	1	1	0
7x38	Lig	ccr_on	0	4.823	0	1	1	0
1x27	7x28	ccr_on	0	4.493	0	1	2	2
2x60	3x32	ccr_on	0	3.471	1	1	1	1
E2x51	E2x52	ccr_on	0	5.092	1	1	1	1
6x62	Lig	ccr_on	0	3.268	0	1	1	0
1x25	Lig	ccr_on	0	3.216	0	0	1	0
5x33	Lig	ccr_on	0	3.18	0	0	1	0
6x62	6x63	ccr_on	0	3.104	0	1	1	2
5x37	6x59	ccr_on	0	2.693	0	0	2	2
6x58	7x30	ccr_on	0	2.42	0	0	2	2
1x26	7x28	ccr_on	0	2.41	0	0	2	2
1x31	7x35	ccr_on	0	2.224	1	0	1	1
6x61	7x30	ccr_on	0	2.11	1	1	1	2
1x27	NT	ccr_on	0	2.046	0	1	2	1
6x65	7x30	ccr_on	0	1.948	0	0	2	2
1x29	1x30	ccr_on	0	1.801	0	0	2	2
7x23	Lig	ccr_on	0	1.73	0	0	1	0
2x67	Lig	ccr_on	0	1.434	0	0	1	0

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Difference Members
	Id	Description
	ccr_off	ccr5_off ccr8_off
	ccr_on	ccr5_on ccr6_on ccr1_on ccr2_on ccr8_on

Network Difference
Value	ccr_off	ccr_on
I_min	3.74	3.225
Number of Linked Nodes	275	279
Number of Specific Nodes	2 (0.73%)	6 (2.15%)
Number of Shared Nodes	273 (99.27%)	273 (97.85%)
Number of Links	299	308
Number of Specific Links	112 (37.46%)	121 (39.29%)
Number of Shared Links	187 (62.54%)	187 (60.71%)
Number of Hubs	27	41
Number of Specific Hubs	2 (7.41%)	16 (39.02%)
Number of Shared Hubs	25 (92.59%)	25 (60.98%)
Average % Shared Neighbours (Jaccard)	49.17
Average % Shared Neighbours (Otsuka)	57.54
Average % Shared Neighbours (Overlap Coefficient)	66.06
Average % Shared Cliques (k3-6)	82.41
Graphlets Similarity	0.521711

Paths Difference
Value	ccr_off	ccr_on
Number Of Nodes in MetaPath	54	56
Specific Nodes in MetaPath	21 (38.89%)	23 (41.07%)
Shared Nodes in MetaPath	273 (99.27%)	273 (99.27%)
Number Of Links MetaPath	54	59
Specific Links in MetaPath	33 (61.11%)	38 (64.41%)
Shared Links in MetaPath	187 (62.54%)	187 (62.54%)
Number of Shortest Paths	45692	55308
Length Of Smallest Path	3	3
Average Path Length	12.4013	14.5253
Length of Longest Path	28	31
Minimum Path Strength	0.7675	0.367
Average Path Strength	7.46566	6.34674
Maximum Path Strength	52.6175	44.6843
Minimum Path Correlation	0.7	0.7
Average Path Correlation	0.939328	0.935651
Maximum Path Correlation	0.995	0.99
Minimum % Of Corr. Nodes	4.7619	4
Average % Of Corr. Nodes	52.3497	52.4765
Maximum % Of Corr. Nodes	100	100
Minimum Path Hubs %	0	0
Average Path Hubs %	39.8608	54.7159
Maximum Path Hubs %	100	100

Details about the values in these tables can be found in the corresponding documentation page .

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