Orange: nodes, hubs and links specific of chemokine_on_gp network

Green: nodes, hubs and links shared by both networks

Purple: nodes, hubs and links specific of chemokine_off network

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Owner: the name of the network the hub belong to or "Shared" if the corresponding hub is present in both networks.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub in the corresponding network.

Num Of Links: the number of links of the corresponding hub in the corresponding network.

ConSurf: this column reports the ConSurf conservation grades of each hub.


Index Hub Owner chemokine_on_gp Avg Int. Strength chemokine_off Avg Int. Strength chemokine_on_gp Num Of Links chemokine_off Num Of Links ConSurf
1G.HN.11 chemokine_on_gp00503
2G.HN.37 chemokine_on_gp00402
3G.HN.52 chemokine_on_gp00404
4G.S1.02 chemokine_on_gp1000504
5G.S1.05 chemokine_on_gp00409
6G.S1.06 chemokine_on_gp200508
7G.S1.07 chemokine_on_gp100409
8G.S2.03 chemokine_on_gp100408
9G.S2.05 chemokine_on_gp12.50403
10G.S2.08 chemokine_on_gp79.16670405
11G.S3.03 chemokine_on_gp900507
12G.S3.04 chemokine_on_gp73.750506
13G.S3.06 chemokine_on_gp1000506
14G.S3.07 chemokine_on_gp200409
15G.s3h2.03 chemokine_on_gp67.50509
16G.H2.06 chemokine_on_gp1000709
17G.H2.07 chemokine_on_gp1000709
18G.H2.09 chemokine_on_gp250408
19G.h2s4.01 chemokine_on_gp96.66670509
20G.S4.03 chemokine_on_gp200407
21G.S4.04 chemokine_on_gp550509
22G.s4h3.04 chemokine_on_gp67.50608
23G.H3.01 chemokine_on_gp00409
24G.H3.09 chemokine_on_gp1000609
25G.H3.13 chemokine_on_gp66.66670505
26G.H3.14 chemokine_on_gp00408
27G.H3.17 chemokine_on_gp72.50604
28G.H3.18 chemokine_on_gp66.250409
29G.S5.03 chemokine_on_gp00408
30G.S5.04 chemokine_on_gp76.250509
31G.S5.05 chemokine_on_gp87.08330809
32G.S5.07 chemokine_on_gp200409
33G.HG.03 chemokine_on_gp12.50406
34G.HG.04 chemokine_on_gp52.50508
35G.HG.07 chemokine_on_gp12.50409
36G.HG.14 chemokine_on_gp00405
37G.hgh4.01 chemokine_on_gp26.66670404
38G.hgh4.02 chemokine_on_gp87.50708
39G.hgh4.05 chemokine_on_gp43.750406
40G.H4.03 chemokine_on_gp400403
41G.H4.10 chemokine_on_gp150406
42G.H4.12 chemokine_on_gp00405
43G.H4.15 chemokine_on_gp64.16670408
44G.h4s6.02 chemokine_on_gp38.750407
45G.S6.02 chemokine_on_gp46.66670508
46G.S6.04 chemokine_on_gp00408
47G.s6h5.01 chemokine_on_gp37.50509
48G.H5.03 chemokine_on_gp250408
49G.H5.08 chemokine_on_gp77.50408
50G.H5.20 chemokine_on_gp200508
51G.H5.25 chemokine_on_gp00406
52G.H5.26 chemokine_on_gp26.66670505
53b.1x4 chemokine_on_gp00608
54b.h2x1 chemokine_on_gp00405
55b.lhb1x3 chemokine_on_gp00502
56b.b1x4 chemokine_on_gp00407
57b.b1x6 chemokine_on_gp37.50409
58b.l1x3 chemokine_on_gp1000709
59b.b2x1 chemokine_on_gp900508
60b.b2x5 chemokine_on_gp1000607
61b.l3x2 chemokine_on_gp54.58330509
62b.b4x2 chemokine_on_gp100408
63b.b4x3 chemokine_on_gp51.66670407
64b.b4x5 chemokine_on_gp62.50407
65b.b4x6 chemokine_on_gp1000709
66b.l4x2 chemokine_on_gp56.66670404
67b.b5x2 chemokine_on_gp00407
68b.b5x3 chemokine_on_gp1000609
69b.b5x5 chemokine_on_gp77.50405
70b.b5x7 chemokine_on_gp800407
71b.l5x1 chemokine_on_gp69.16670508
72b.l5x5 chemokine_on_gp87.50709
73b.b6x5 chemokine_on_gp900706
74b.l6x5 chemokine_on_gp54.16670404
75b.b7x1 chemokine_on_gp1000504
76b.b7x4 chemokine_on_gp12.50408
77b.l7x2 chemokine_on_gp81.250609
78b.l7x4 chemokine_on_gp150409
79b.b8x4 chemokine_on_gp1000506
80b.l8x1 chemokine_on_gp51.66670405
81b.l8x3 chemokine_on_gp00403
82b.l9x3 chemokine_on_gp900709
83b.l9x6 chemokine_on_gp10001008
84b.b10x5 chemokine_on_gp77.50609
85b.l10x1 chemokine_on_gp58.750403
86b.b11x4 chemokine_on_gp850509
87b.l11x2 chemokine_on_gp72.50409
88b.b12x3 chemokine_on_gp41.66670408
89b.b12x6 chemokine_on_gp1000708
90b.b13x7 chemokine_on_gp96.66670507
91b.l13x3 chemokine_on_gp1000609
92b.l13x6 chemokine_on_gp82.50509
93b.l13x7 chemokine_on_gp250409
94b.b14x3 chemokine_on_gp00405
95b.b15x1 chemokine_on_gp650709
96b.b15x2 chemokine_on_gp60.41670406
97b.b15x3 chemokine_on_gp700409
98b.l15x1 chemokine_on_gp350407
99b.l15x2 chemokine_on_gp67.50509
100b.b16x4 chemokine_on_gp900406
101b.b16x5 chemokine_on_gp55.83330505
102b.b16x6 chemokine_on_gp1000608
103b.b17x4 chemokine_on_gp00405
104b.b17x5 chemokine_on_gp00407
105b.b17x7 chemokine_on_gp83.750408
106b.l17x3 chemokine_on_gp1000709
107b.l17x6 chemokine_on_gp77.50509
108b.b18x3 chemokine_on_gp86.66670408
109b.b18x5 chemokine_on_gp00405
110b.l18x1 chemokine_on_gp1000806
111b.l18x2 chemokine_on_gp550407
112b.l18x3 chemokine_on_gp00405
113b.b19x2 chemokine_on_gp1000706
114b.b19x4 chemokine_on_gp80.41670508
115b.l19x2 chemokine_on_gp400509
116b.b20x2 chemokine_on_gp37.50506
117b.b20x4 chemokine_on_gp1000508
118b.b20x6 chemokine_on_gp1000506
119b.b20x7 chemokine_on_gp00409
120b.l20x2 chemokine_on_gp00509
121b.b21x1 chemokine_on_gp700507
122b.b21x2 chemokine_on_gp00406
123b.b21x5 chemokine_on_gp00404
124b.b21x7 chemokine_on_gp82.50505
125b.b22x5 chemokine_on_gp84.16670607
126b.l22x5 chemokine_on_gp96.66670709
127b.b23x1 chemokine_on_gp00405
128b.b23x6 chemokine_on_gp1000607
129b.l23x1 chemokine_on_gp100406
130b.b24x4 chemokine_on_gp78.33330406
131b.b24x6 chemokine_on_gp1000408
132b.b24x7 chemokine_on_gp37.50409
133b.l24x2 chemokine_on_gp00406
134b.l24x3 chemokine_on_gp12.50505
135b.l25x3 chemokine_on_gp1000509
136b.b26x3 chemokine_on_gp47.50406
137b.b27x1 chemokine_on_gp00406
138b.l27x1 chemokine_on_gp1000709
139b.l27x2 chemokine_on_gp71.66670409
140b.b28x3 chemokine_on_gp16.66670507
141b.b28x4 chemokine_on_gp950406
142b.b28x6 chemokine_on_gp1000409
143g.h1x1 chemokine_on_gp00502
144g.h1x8 chemokine_on_gp00407
145g.l1x4 chemokine_on_gp18.750508
146g.h2x11 chemokine_on_gp74.16670406
147g.ctx3 chemokine_on_gp900609
148g.ctx5 chemokine_on_gp250409
149g.ctx6 chemokine_on_gp00506
150g.ctx14 chemokine_on_gp26.66670409
151g.ctx15 chemokine_on_gp64.16670409
152g.ctx16 chemokine_on_gp900708
153NT chemokine_on_gp83.750533
1541x30 chemokine_on_gp00425
1551x50 chemokine_on_gp00439
1561x57 chemokine_on_gp00427
1571x59 chemokine_on_gp00424
1582x38 chemokine_on_gp300436
1592x46 chemokine_on_gp200419
1602x50 chemokine_on_gp18.33330439
1613x42 chemokine_on_gp4050437
1623x49 chemokine_on_gp558.33333438
163I2x52 chemokine_on_gp00424
1644x41 chemokine_on_gp00412
1655x47 chemokine_on_gp00418
166I3 chemokine_on_gp47.50414
1676x30 chemokine_on_gp00427
1686x49 chemokine_on_gp00426
1697x43 chemokine_on_gp00415
1707x45 chemokine_on_gp400539
1717x49 chemokine_on_gp61.250619
1727x52 chemokine_on_gp00438
173Lig Shared10010023230
1741x35 Shared00445
1751x39 Shared77.566.6667578
1762x42 Shared1000657
1772x53 Shared6525446
178E1x50 Shared100100578
179E1x52 Shared41.66670647
1803x32 Shared53.7550657
1813x33 Shared250445
1823x37 Shared8575557
1833x50 Shared900549
1843x51 Shared43.7541.6667468
1854x50 Shared2525459
186E2 Shared10010014144
187E2x52 Shared2550445
1885x50 Shared00459
1895x58 Shared1000749
1906x44 Shared55100569
1916x48 Shared100100559
1926x51 Shared74.1667100547
193E3 Shared51.2525754
1947x42 Shared10075557
1957x53 Shared1000659
1968x50 Shared900548
1978x54 Shared00446
198I2x57 Shared250440
1991x60 chemokine_off00145
2002x40 chemokine_off00348
2012x44 chemokine_off00346
2022x60 chemokine_off60.8333100356
2033x41 chemokine_off00245
2043x43 chemokine_off00348
2053x52 chemokine_off00144
2064x42 chemokine_off00347
2075x35 chemokine_off1025342
2085x60 chemokine_off00344
2095x61 chemokine_off00258
2108x48 chemokine_off00345
   
Orange: nodes, hubs and links specific of chemokine_on_gp network

Green: nodes, hubs and links shared by both networks

Purple: nodes, hubs and links specific of chemokine_off network

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Owner: the name of the network the link belong to or "Shared" if the corresponding link is present in both networks.

Recurrence: the relative Recurrence in the filtered pool of shortest paths.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.


Index Node1 Node2 Owner chemokine_on_gp Recurrence chemokine_off Recurrence chemokine_on_gp Hub1? chemokine_off Hub1? chemokine_on_gp Hub2? chemokine_off Hub2? ConSurf1 ConSurf2
1b.b2x3 b.b2x5 chemokine_on_gp24.40210NoNoYesNo67
2b.b26x2 b.b2x3 chemokine_on_gp24.59740NoNoNoNo76
3b.b26x1 b.b26x2 chemokine_on_gp24.79740NoNoNoNo97
4b.b26x1 b.l27x1 chemokine_on_gp24.9990NoNoYesNo99
5b.b2x1 b.l27x1 chemokine_on_gp16.39330YesNoYesNo89
6b.b2x1 b.l3x1 chemokine_on_gp16.75780YesNoNoNo89
7b.l3x1 b.l5x5 chemokine_on_gp17.09520NoNoYesNo99
8G.h2s4.01 b.l5x5 chemokine_on_gp12.97490YesNoYesNo99
9G.S1.05 G.h2s4.01 chemokine_on_gp14.86640YesNoYesNo99
10G.S1.05 G.S1.07 chemokine_on_gp50.64340YesNoYesNo99
11G.S1.07 G.S4.04 chemokine_on_gp50.74810YesNoYesNo99
12G.S4.04 G.S5.04 chemokine_on_gp94.60980YesNoYesNo99
13G.S5.04 G.S5.06 chemokine_on_gp94.93250YesNoNoNo98
14G.S5.06 G.s4h3.01 chemokine_on_gp95.35260NoNoNoNo87
15G.HG.04 G.s4h3.01 chemokine_on_gp96.37420YesNoNoNo87
16G.H4.03 G.HG.04 chemokine_on_gp98.96970YesNoYesNo38
17G.H4.03 G.HG.01 chemokine_on_gp99.76820YesNoNoNo35
18G.HG.01 G.s6h5.02 chemokine_on_gp99.7860NoNoNoNo57
19G.s6h5.02 G.s6h5.05 chemokine_on_gp99.80370NoNoNoNo79
20G.s6h5.01 G.s6h5.05 chemokine_on_gp99.89060YesNoNoNo99
21G.S5.05 G.s6h5.01 chemokine_on_gp99.57680YesNoYesNo99
22G.S4.03 G.S5.05 chemokine_on_gp99.43090YesNoYesNo79
23G.S1.04 G.S4.03 chemokine_on_gp1000NoNoYesNo77
24G.S1.02 G.S1.04 chemokine_on_gp49.91730YesNoNoNo47
25G.H5.11 G.S1.02 chemokine_on_gp49.5960NoNoYesNo84
26G.H5.11 G.H5.15 chemokine_on_gp99.66840NoNoNoNo88
27G.H5.15 G.H5.19 chemokine_on_gp99.48010NoNoNoNo88
283x53 G.H5.19 chemokine_on_gp99.38580NoNoNoNo88
29G.H3.17 b.l27x1 chemokine_on_gp11.6670YesNoYesNo49
30G.H3.15 G.H3.17 chemokine_on_gp38.33490NoNoYesNo84
31G.H3.15 G.H3.18 chemokine_on_gp38.43080NoNoYesNo89
32G.H3.18 G.S4.02 chemokine_on_gp35.60850YesNoNoNo97
33G.S1.05 G.S4.02 chemokine_on_gp35.77250YesNoNoNo97
34G.S1.04 G.S3.03 chemokine_on_gp50.09570NoNoYesNo77
35G.H5.11 G.S3.03 chemokine_on_gp50.16630NoNoYesNo87
363x49 I2x57 chemokine_on_gp49.31240.164669YesNoYesYes80
372x42 3x49 chemokine_on_gp49.08490YesYesYesNo78
38b.b2x4 b.b6x5 chemokine_on_gp11.35420NoNoYesNo66
39b.b10x4 b.b2x4 chemokine_on_gp11.44310NoNoNoNo66
40b.b10x2 b.b10x4 chemokine_on_gp10.9640NoNoNoNo66
41b.b10x2 b.b14x3 chemokine_on_gp10.50410NoNoYesNo65
42b.b11x5 b.b14x3 chemokine_on_gp13.06240NoNoYesNo65
43b.b10x1 b.b11x5 chemokine_on_gp16.98430NoNoNoNo96
44b.b10x1 b.l9x6 chemokine_on_gp17.09720NoNoYesNo98
452x42 3x46 chemokine_on_gp90.15242.07713YesYesNoNo79
463x46 3x50 chemokine_on_gp31.09850NoNoYesYes99
473x50 5x58 chemokine_on_gp14.72450YesYesYesYes99
48G.H2.07 b.l9x6 chemokine_on_gp50.6370YesNoYesNo98
49G.H2.06 b.l9x6 chemokine_on_gp37.01710YesNoYesNo98
50G.H2.04 G.H2.07 chemokine_on_gp48.80240NoNoYesNo99
51G.H2.04 G.H3.08 chemokine_on_gp48.85480NoNoNoNo99
52G.H2.06 b.l17x6 chemokine_on_gp36.34340YesNoYesNo99
53G.H5.20 G.H5.25 chemokine_on_gp14.11840YesNoYesNo86
543x50 G.H5.25 chemokine_on_gp16.93660YesYesYesNo96
55G.H5.20 G.H5.26 chemokine_on_gp11.19150YesNoYesNo85
56b.l17x5 b.l17x6 chemokine_on_gp37.25990NoNoYesNo69
57b.l17x5 b.l19x2 chemokine_on_gp37.1760NoNoYesNo69
58b.l17x3 b.l19x2 chemokine_on_gp28.83630YesNoYesNo99
59b.b19x4 b.l17x3 chemokine_on_gp20.88320YesNoYesNo89
60b.b19x2 b.b19x4 chemokine_on_gp10.96970YesNoYesNo68
61b.b17x7 b.b21x1 chemokine_on_gp26.93290YesNoYesNo87
62b.1x19 b.b21x1 chemokine_on_gp22.91110NoNoYesNo67
63b.1x15 b.1x19 chemokine_on_gp20.37510NoNoNoNo76
64b.1x12 b.1x15 chemokine_on_gp18.3110NoNoNoNo67
65b.1x12 g.h1x11 chemokine_on_gp17.79470NoNoNoNo69
66b.1x11 g.h1x11 chemokine_on_gp16.76180NoNoNoNo89
67b.1x11 g.h1x12 chemokine_on_gp16.24520NoNoNoNo86
68g.h1x12 g.h1x8 chemokine_on_gp14.17780NoNoYesNo67
69b.b17x7 b.b20x6 chemokine_on_gp21.29930YesNoYesNo86
70b.b20x4 b.b20x6 chemokine_on_gp14.45290YesNoYesNo86
71g.ctx3 g.ctx6 chemokine_on_gp13.20860YesNoYesNo96
72b.l22x5 g.ctx6 chemokine_on_gp13.20740YesNoYesNo96
73b.l23x1 b.l25x6 chemokine_on_gp29.26660YesNoNoNo68
74b.l21x7 b.l23x1 chemokine_on_gp13.63870NoNoYesNo56
75b.l21x7 b.l23x2 chemokine_on_gp13.49450NoNoNoNo58
76b.b23x6 b.l23x2 chemokine_on_gp12.77330YesNoNoNo78
77b.b23x6 b.b24x6 chemokine_on_gp11.03390YesNoYesNo78
78b.b22x1 b.l23x1 chemokine_on_gp15.56980NoNoYesNo86
79b.b22x1 b.b22x2 chemokine_on_gp15.42860NoNoNoNo88
803x46 7x53 chemokine_on_gp58.80410NoNoYesYes99
817x49 7x53 chemokine_on_gp57.70070YesNoYesYes99
822x50 7x49 chemokine_on_gp40.84072.02802YesNoYesNo99
837x45 7x49 chemokine_on_gp13.57840YesNoYesNo99
84G.H3.08 G.S4.04 chemokine_on_gp48.88760NoNoYesNo99
85b.b21x7 b.b24x6 chemokine_on_gp10.80390YesNoYesNo58
86b.b22x2 b.b26x3 chemokine_on_gp15.29360NoNoYesNo86
87G.H3.17 b.l25x6 chemokine_on_gp26.22430YesNoNoNo48
883x53 I2x57 Shared99.291327.2743NoNoYesYes80
892x38 I2x57 Shared49.69528.9672YesNoYesYes60
902x38 2x42 Shared49.065732.1277YesNoYesYes67
912x50 7x46 Shared38.570459.5089YesNoNoNo98
922x53 7x46 Shared38.301665.0123YesYesNoNo68
932x53 3x32 Shared29.27642.0425YesYesYesYes67
943x32 Lig Shared26.187327.1414YesYesYesYes70
951x50 2x50 chemokine_off2.3016855.8111YesNoYesNo99
961x50 2x51 chemokine_off0.56165412.0959YesNoNoNo97
971x51 2x51 chemokine_off010.0939NoNoNoNo47
987x42 Lig chemokine_off023.0565YesYesYesYes70
992x53 7x42 chemokine_off7.9527326.607YesYesYesYes67
1001x50 7x50 chemokine_off2.2329842.6867YesNoNoNo99
1011x53 7x50 chemokine_off036.9753NoNoNoNo89
1027x38 Lig chemokine_off0.055468377.2497NoNoYesYes60
1036x51 7x38 chemokine_off0.84349277.2295YesYesNoNo76
1046x48 6x51 chemokine_off078.674YesYesYesYes97
1056x44 6x48 chemokine_off0.210709100YesYesYesYes99
1063x40 6x44 chemokine_off059.038NoNoYesYes79
1073x40 5x50 chemokine_off058.2204NoNoYesYes79
1083x41 5x50 chemokine_off054.0459NoYesYesYes59
1093x41 4x49 chemokine_off1.6964350.6023NoYesNoNo56
1103x45 4x49 chemokine_off4.0480243.3829NoNoNoNo66
1112x42 3x45 chemokine_off4.3122840.7656YesYesNoNo76
1123x50 3x53 chemokine_off026.477YesYesNoNo98
1132x39 3x50 chemokine_off017.4057NoNoYesYes89
1142x37 2x39 chemokine_off016.3426NoNoNoNo88
1152x37 2x40 chemokine_off8.0461411.9457NoNoNoYes88
1161x53 7x53 chemokine_off033.1244NoNoYesYes89
1177x53 8x50 chemokine_off026.2141YesYesYesYes98
1181x56 8x50 chemokine_off1.4597618.7693NoNoYesYes78
1192x60 Lig chemokine_off0.017883210.1488NoYesYesYes60
120E1x50 E1x52 chemokine_off5.0841411.3477YesYesYesYes87
121E2 Lig chemokine_off6.9621316.1144YesYesYesYes40
1223x32 3x33 chemokine_off2.3417423.8278YesYesYesYes75
1233x33 3x37 chemokine_off2.4032726.8843YesYesYesYes57
1243x36 3x37 chemokine_off3.7663922.8138NoNoYesYes77
1253x36 6x48 chemokine_off4.2908626.3961NoNoYesYes79
1263x43 6x44 chemokine_off036.3686NoYesYesYes89
1276x44 6x45 chemokine_off030.507YesYesNoNo96
1286x41 6x45 chemokine_off027.855NoNoNoNo86
1293x43 6x41 chemokine_off028.5454NoYesNoNo88
1305x54 6x41 chemokine_off054.3348NoNoNoNo78
1313x47 5x54 chemokine_off0.20454652.6246NoNoNoNo97
1323x47 5x58 chemokine_off5.0712150.7208NoNoYesYes99
1335x58 5x61 chemokine_off0.75205539.6331YesYesNoYes98
1343x51 5x61 chemokine_off028.3085YesYesNoYes88
1353x51 5x60 chemokine_off1.1751910.2383YesYesNoYes84
1365x40 Lig chemokine_off015.4124NoNoYesYes50
1375x40 6x59 chemokine_off0.87405514.6815NoNoNoNo55
1386x59 6x60 chemokine_off013.6935NoNoNoNo55
1396x60 E3 chemokine_off0.56685810.6746NoNoYesYes54

Here, those paths that begin and end at given residue pair(s) or that pass through a residue are used to generate a novel metapath. Such a path filtering is particularly recommended if some information on allosteric residues is available. The selection syntax for a residue pair ("Pairs") is C:C:c534,A:A:?600 (the lower-case "c" stands for cytosine and "?" indicates any non standard amino acid or nucleotide residue). Selection of more than one apical residue pair has the following syntax: C:C:c534,A:A:?600,C:C:c534,A:A:E41. Only one residue can be selected as a tail ("Tail"). For midway residue(s), each residue must be separated by a comma as well e.g. A:A:?600,A:A:E41.

Midway



Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.


2D representation of the interactions of this orthosteric/allosteric ligand.


Node1Node2OwnerNet1LinkStrengthNet2LinkStrengthComm1Comm2Node1ShellNode2Shell
1x277x32Shared4.52252.82350022
1x351x39Shared10.45337.577171011
1x35Ligchemokine_off4.947501010
1x392x57Shared3.77754.810871212
1x397x39Shared5.481672.110331212
1x397x42Shared8.046675.727921211
1x39Ligchemokine_off4.8301210
2x533x32Shared6.4958.377671221
2x537x42Shared7.495.822921221
2x562x60Shared5.761673.320130221
2x60E1x50chemokine_off4.9201212
2x603x32Shared3.858336.438371211
2x607x42chemokine_off4.9501211
2x60LigShared19.599213.22881210
2x63E1x50Shared7.865837.078581212
E1x49E2Shared12.73674.303581221
E1x50E2Shared4.920834.715751221
3x223x26Shared4.974173.008621222
3x22E2Shared10.6556.008131221
3x26E2chemokine_off4.102501021
3x294x65Shared8.536679.406831212
3x29LigShared6.114173.359631210
3x323x33Shared4.54254.669461212
3x327x42Shared5.319173.27151211
3x32LigShared8.174177.037041210
3x334x61Shared16.21427.105080022
4x615x39chemokine_off4.542500222
4x64E2Shared17.704210.47351221
4x645x35Shared9.019173.749581222
4x65E2x52Shared4.99255.895210221
E2E2Shared52.617547.70581211
E2E2x52Shared8.1254.888461211
5x35E2Shared10.03089.610371221
5x36E2Shared6.214173.3560211
5x335x37chemokine_off5.43500022
5x376x60chemokine_off3.927500022
5x406x59Shared9.37756.231121012
6x486x51chemokine_off6.5108302321
6x516x55Shared8.939178.2160212
6x517x37Shared6.033335.52050212
6x517x38Shared7.689177.310130211
6x547x34Shared3.82253.318130021
6x547x37Shared3.573.815960022
6x587x30Shared3.619172.600420212
6x587x34chemokine_off3.6666700211
6x596x60chemokine_off4.972500022
7x35LigShared12.03673.661330210
7x38LigShared10.71177.105251210
7x42Ligchemokine_off9.17501210
E2x52LigShared6.9852.89151210
E2LigShared27.859242.01311210
5x40Ligchemokine_off3.84501010
2x63LigShared4.871673.719081210
E2x51LigShared6.743338.900831210
1x24Ligchemokine_off3.6891701010
7x31LigShared4.291673.774420210
7x34LigShared3.795834.936541210
LigNTShared16.705845.15841201
7x27LigShared3.601678.508120010
5x32LigShared5.94254.020210
1x241x27chemokine_off5.1333301012
2x63E2Shared4.070833.662421211
E2E2x51Shared7.93257.775081211
6x61E3Shared4.939174.778790021
6x62E3chemokine_off5.07500211
7x26E3Shared5.244175.248290221
4x61E2x52Shared4.11755.0310221
6x60E3Shared5.19254.594420221
6x636x64chemokine_off3.37500022
6x626x63chemokine_off3.207500212
7x24NTShared3.033335.770920021
1x31Ligchemokine_off2.7300010
1x392x61Shared2.669173.384581212
1x352x64Shared2.495833.456171012
1x247x28chemokine_off2.3066701012
5x31E2chemokine_off2.23500021
1x381x39chemokine_off2.1533300021
1x341x35chemokine_off1.6466700021
1x25NTchemokine_off1.1200021
1x28LigShared1.05753.40850210
6x65E3chemokine_off0.42500021
E3Ligchemokine_on_gp03.469420210
NTNTchemokine_on_gp017.98231211
1x311x35chemokine_on_gp02.817120011
1x357x35chemokine_on_gp03.698711011
1x387x39chemokine_on_gp03.040750022
4x614x65chemokine_on_gp02.852250222
5x39E2chemokine_on_gp04.758380221
5x32E2chemokine_on_gp03.796710211
5x406x55chemokine_on_gp05.26851012
5x406x58chemokine_on_gp03.74751011
6x516x52chemokine_on_gp03.354790212
6x64E3chemokine_on_gp02.530460021
7x387x42chemokine_on_gp06.375211211
1x247x31chemokine_on_gp02.59751011
2x563x32chemokine_on_gp02.707880221
2x577x42chemokine_on_gp05.539040221
5x376x59chemokine_on_gp02.757920022
6x51Ligchemokine_on_gp02.97950210
6x58Ligchemokine_on_gp03.033380210
1x277x31chemokine_on_gp02.60250021
5x36Ligchemokine_on_gp04.342370210
6x62Ligchemokine_on_gp03.484540210
E3E3chemokine_on_gp03.442870211
5x376x62chemokine_on_gp03.039670021
7x28NTchemokine_on_gp03.333920221
5x36E2x51chemokine_on_gp03.631830211
1x317x32chemokine_on_gp03.01250012
5x376x63chemokine_on_gp02.25150022
5x336x62chemokine_on_gp01.952750021
1x251x28chemokine_on_gp00.7420021
6x657x30chemokine_on_gp00.7310022
2x67Ligchemokine_on_gp00.7170010

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Difference Members
Id Description
chemokine_on_gp ccr_on_gp
cxcr_on_gp
chemokine_off ccr_off
cxcr_off
Network Difference
Value chemokine_on_gp chemokine_off
Imin 2.52225 3.39917
Number of Linked Nodes 945 278
Number of Specific Nodes 667 (70.58%) 0  (0.00%)
Number of Shared Nodes 278 (29.42%) 278  (100.00%)
Number of Links 1178 304
Number of Specific Links 986 (83.70%) 112  (36.84%)
Number of Shared Links 192 (16.30%) 192  (63.16%)
Number of Hubs 198 38
Number of Specific Hubs 172 (86.87%) 12  (31.58%)
Number of Shared Hubs 26 (13.13%) 26  (68.42%)
Average % Shared Neighbours (Jaccard) 14.01
Average % Shared Neighbours (Otsuka) 16.82
Average % Shared Neighbours (Overlap Coefficient) 20.13
Average % Shared Cliques (k3-6) 52.07
Graphlets Similarity 0.68371
Paths Difference
Value chemokine_on_gp chemokine_off
Number Of Nodes in MetaPath 94 51
Specific Nodes in MetaPath 82 (87.23%) 39  (76.47%)
Shared Nodes in MetaPath 278 (29.42%) 278  (29.42%)
Number Of Links MetaPath 94 52
Specific Links in MetaPath 87 (92.55%) 45  (86.54%)
Shared Links in MetaPath 192 (16.30%) 192  (16.30%)
Number of Shortest Paths 2753298 62688
Length Of Smallest Path 3 3
Average Path Length 36.6186 14.6356
Length of Longest Path 65 36
Minimum Path Strength 0.278 0.949722
Average Path Strength 4.944 5.94368
Maximum Path Strength 32.5483 22.7817
Minimum Path Correlation 0.704792 0.7
Average Path Correlation 0.98299 0.906068
Maximum Path Correlation 1 0.983333
Minimum % Of Corr. Nodes 1.81818 3.22581
Average % Of Corr. Nodes 36.7208 41.0465
Maximum % Of Corr. Nodes 100 100
Minimum Path Hubs % 0 0
Average Path Hubs % 53.0722 45.7119
Maximum Path Hubs % 100 100

Details about the values in these tables can be found in the corresponding documentation page .

You can download a compressed (zip) file with structure(s), 3D outputs (as PyMol and VMD scripts) and numerical data files (as csv and plain text files).

Download chemokine_off_on_gp.zip<



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