psnGPCR

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Orange: nodes, hubs and links specific of class-b1_on network

Green: nodes, hubs and links shared by both networks

Purple: nodes, hubs and links specific of class-b2_on network

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Owner: the name of the network the link belong to or "Shared" if the corresponding link is present in both networks.

Strength: the interaction strength between the two nodes or 0 if the link is not present.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Owner	class-b1_on Int. Strength	class-b2_on Int. Strength	class-b1_on Hub1?	class-b2_on Hub1?	class-b1_on Hub2?	class-b2_on Hub2?	ConSurf1	ConSurf2
1	Lig	Lig	class-b1_on	100	0	Yes	No	Yes	No	0	0
2	3x33	Lig	class-b1_on	100	0	Yes	Yes	Yes	No	7	0
3	3x36	Lig	class-b1_on	100	0	No	No	Yes	No	6	0
4	5x41	Lig	class-b1_on	100	0	Yes	No	Yes	No	6	0
5	7x34	Lig	class-b1_on	100	0	No	No	Yes	No	5	0
6	7x37	Lig	class-b1_on	100	0	No	Yes	Yes	No	8	0
7	2x57	Lig	class-b1_on	100	0	Yes	No	Yes	No	7	0
8	3x32	Lig	class-b1_on	100	0	Yes	No	Yes	No	6	0
9	7x38	Lig	class-b1_on	100	0	No	No	Yes	No	7	0
10	E3	Lig	class-b1_on	100	0	Yes	Yes	Yes	No	4	0
11	7x30	Lig	class-b1_on	100	0	No	No	Yes	No	5	0
12	1x32	Lig	class-b1_on	100	0	No	No	Yes	No	5	0
13	1x36	Lig	class-b1_on	100	0	Yes	No	Yes	No	5	0
14	1x39	Lig	class-b1_on	100	0	Yes	No	Yes	No	7	0
15	2x60	Lig	class-b1_on	100	0	No	No	Yes	No	6	0
16	E2x52	Lig	class-b1_on	100	0	No	Yes	Yes	No	5	0
17	1x29	Lig	class-b1_on	100	0	No	No	Yes	No	2	0
18	Lig	NT	class-b1_on	100	0	Yes	No	Yes	Yes	0	5
19	E1	Lig	class-b1_on	100	0	Yes	Yes	Yes	No	3	0
20	E1	NT	class-b1_on	100	0	Yes	Yes	Yes	Yes	3	5
21	1x31	7x31	class-b1_on	100	0	No	No	No	No	4	4
22	1x35	7x38	class-b1_on	100	0	No	No	No	No	6	7
23	1x36	1x39	class-b1_on	100	0	Yes	No	Yes	No	5	7
24	1x36	2x61	class-b1_on	100	0	Yes	No	No	No	5	7
25	1x39	1x43	class-b1_on	100	0	Yes	No	Yes	No	7	7
26	1x39	2x61	class-b1_on	100	0	Yes	No	No	No	7	7
27	1x39	7x38	class-b1_on	100	0	Yes	No	No	No	7	7
28	1x39	7x42	class-b1_on	100	0	Yes	No	No	No	7	9
29	1x43	2x53	class-b1_on	100	0	Yes	No	No	No	7	8
30	1x43	2x57	class-b1_on	100	0	Yes	No	Yes	No	7	7
31	1x43	7x42	class-b1_on	100	0	Yes	No	No	No	7	9
32	1x50	7x50	class-b1_on	100	0	Yes	Yes	No	Yes	9	8
33	2x39	2x40	class-b1_on	100	0	No	No	Yes	Yes	9	9
34	2x42	3x49	class-b1_on	100	0	No	No	Yes	No	8	8
35	2x43	7x53	class-b1_on	100	0	No	Yes	No	No	9	8
36	2x46	2x50	class-b1_on	100	0	No	No	Yes	No	9	8
37	2x46	3x46	class-b1_on	100	0	No	No	Yes	No	9	9
38	2x49	3x39	class-b1_on	100	0	No	No	No	No	9	9
39	2x50	7x46	class-b1_on	100	0	Yes	No	No	No	8	9
40	2x53	3x39	class-b1_on	100	0	No	No	No	No	8	9
41	2x56	3x35	class-b1_on	100	0	No	No	Yes	No	6	5
42	2x57	2x61	class-b1_on	100	0	Yes	No	No	No	7	7
43	2x60	3x32	class-b1_on	100	0	No	No	Yes	No	6	6
44	3x26	E2x51	class-b1_on	100	0	No	No	Yes	Yes	8	8
45	3x31	3x35	class-b1_on	100	0	No	No	Yes	No	5	5
46	3x33	4x60	class-b1_on	100	0	Yes	Yes	Yes	No	7	8
47	3x34	4x57	class-b1_on	100	0	Yes	Yes	No	No	9	6
48	3x36	3x40	class-b1_on	100	0	No	No	No	No	6	8
49	3x41	4x52	class-b1_on	100	0	No	No	No	No	6	3
50	3x49	4x46	class-b1_on	100	0	Yes	No	No	No	8	7
51	3x51	5x60	class-b1_on	100	0	No	No	No	No	8	8
52	4x56	5x46	class-b1_on	100	0	No	No	No	No	5	8
53	4x60	4x64	class-b1_on	100	0	Yes	No	Yes	No	8	8
54	4x60	5x421	class-b1_on	100	0	Yes	No	No	No	8	8
55	4x60	5x43	class-b1_on	100	0	Yes	No	No	No	8	7
56	4x64	4x68	class-b1_on	100	0	Yes	No	No	No	8	6
57	4x64	E2x51	class-b1_on	100	0	Yes	No	Yes	Yes	8	8
58	4x68	E2	class-b1_on	100	0	No	No	Yes	Yes	6	5
59	E2	E2x51	class-b1_on	100	0	Yes	Yes	Yes	Yes	5	8
60	5x41	E2	class-b1_on	100	0	Yes	No	Yes	Yes	6	5
61	5x41	5x43	class-b1_on	100	0	Yes	No	No	No	6	7
62	5x42	5x44	class-b1_on	100	0	No	No	No	No	7	6
63	5x55	6x49	class-b1_on	100	0	No	No	No	No	6	6
64	5x60	5x63	class-b1_on	100	0	No	No	No	No	8	7
65	6x47	6x48	class-b1_on	100	0	Yes	No	Yes	Yes	8	8
66	6x47	7x45	class-b1_on	100	0	Yes	No	Yes	No	8	9
67	6x51	7x33	class-b1_on	100	0	No	No	No	No	7	7
68	7x33	7x37	class-b1_on	100	0	No	No	No	Yes	7	8
69	7x36	7x40	class-b1_on	100	0	No	No	No	No	4	6
70	7x39	7x43	class-b1_on	100	0	No	No	No	No	5	7
71	7x51	7x55	class-b1_on	100	0	No	No	No	No	6	8
72	7x52	7x53	class-b1_on	100	0	No	Yes	No	No	8	8
73	E1	E2	class-b1_on	100	0	Yes	Yes	Yes	Yes	3	5
74	3x44	5x54	class-b1_on	100	0	Yes	No	No	No	8	9
75	4x64	5x40	class-b1_on	100	0	Yes	No	Yes	Yes	8	4
76	1x29	1x33	class-b1_on	100	0	No	No	No	No	2	3
77	5x44	Lig	class-b1_on	100	0	No	No	Yes	No	6	0
78	1x25	Lig	class-b1_on	100	0	No	No	Yes	No	0	0
79	2x38	I2	class-b1_on	100	0	Yes	No	Yes	Yes	7	7
80	3x49	I2	class-b1_on	100	0	Yes	No	Yes	Yes	8	7
81	1x54	2x44	class-b1_on	35	0	No	No	No	No	6	6
82	3x44	3x48	class-b1_on	60	0	Yes	No	No	No	8	6
83	7x54	7x55	class-b1_on	82	0	No	No	No	No	9	8
84	3x47	6x44	class-b1_on	45.2083	0	No	No	Yes	No	8	9
85	6x43	6x44	class-b1_on	44	0	No	No	Yes	No	9	9
86	8x47	8x49	class-b1_on	62	0	No	No	No	No	9	9
87	5x69	6x32	class-b1_on	56.6667	0	Yes	No	No	No	8	8
88	6x32	6x35	class-b1_on	40	0	No	No	No	No	8	8
89	3x29	3x33	class-b1_on	35	0	No	No	Yes	Yes	5	7
90	6x50	6x51	class-b1_on	80	0	No	No	No	No	6	7
91	5x51	6x48	class-b1_on	45	0	No	No	Yes	Yes	7	8
92	1x56	7x54	class-b1_on	35.1667	0	No	No	No	No	8	9
93	2x64	E2x52	class-b1_on	60	0	No	No	No	Yes	7	5
94	E2x50	E2x52	class-b1_on	29	0	No	No	No	Yes	9	5
95	6x35	6x39	class-b1_on	39.2083	0	No	No	No	No	8	8
96	7x29	E3	class-b1_on	33.9583	0	No	No	Yes	Yes	3	4
97	7x42	7x43	class-b1_on	51.25	0	No	No	No	No	9	7
98	8x58	8x62	class-b1_on	45	0	Yes	No	No	No	5	4
99	6x41	6x42	class-b1_on	40	0	No	No	No	No	8	9
100	1x28	Lig	class-b1_on	39.1667	0	No	No	Yes	No	0	0
101	5x53	5x57	class-b1_on	42.5	0	No	No	No	No	6	8
102	2x65	Lig	class-b1_on	40	0	No	No	Yes	No	4	0
103	1x46	7x46	class-b1_on	17.25	0	No	No	No	No	9	9
104	4x65	E2x51	class-b1_on	37.5	0	No	No	Yes	Yes	3	8
105	5x37	5x40	class-b1_on	50	0	No	No	Yes	Yes	5	4
106	2x50	7x49	class-b1_on	33.125	0	Yes	No	No	No	8	9
107	4x63	5x40	class-b1_on	50	0	No	No	Yes	Yes	4	4
108	6x29	I3	class-b1_on	45	0	Yes	No	No	Yes	5	0
109	1x52	7x55	class-b1_on	33.5	0	No	No	No	No	4	8
110	1x40	2x58	class-b1_on	22.3333	0	No	No	No	No	7	7
111	3x30	4x61	class-b1_on	15	0	No	No	No	No	5	5
112	6x54	E3	class-b1_on	40	0	No	No	Yes	Yes	5	4
113	6x45	6x47	class-b1_on	26.875	0	No	No	Yes	No	9	8
114	4x61	E2x51	class-b1_on	15.4167	0	No	No	Yes	Yes	5	8
115	1x44	2x58	class-b1_on	30	0	No	No	No	No	6	7
116	1x24	NT	class-b1_on	25	0	No	No	Yes	Yes	0	5
117	6x53	Lig	class-b1_on	30	0	No	No	Yes	No	4	0
118	5x39	5x42	class-b1_on	30.2083	0	No	No	No	No	3	7
119	8x58	8x61	class-b1_on	33.875	0	Yes	No	No	No	5	4
120	5x56	5x60	class-b1_on	25.2083	0	No	No	No	No	5	8
121	4x66	4x67	class-b1_on	22.5	0	No	No	No	No	3	3
122	2x68	Lig	class-b1_on	20	0	No	No	Yes	No	3	0
123	1x21	Lig	class-b1_on	30	0	No	No	Yes	No	0	0
124	6x52	Lig	class-b1_on	20	0	No	No	Yes	No	6	0
125	5x66	5x70	class-b1_on	40	0	No	No	No	No	6	6
126	3x24	E1	class-b1_on	27.5	0	No	Yes	Yes	Yes	3	3
127	8x58	8x59	class-b1_on	35.625	0	Yes	No	No	No	5	4
128	5x61	6x40	class-b1_on	21.6667	0	No	No	No	No	9	9
129	4x68	5x38	class-b1_on	20	0	No	No	No	No	6	5
130	5x65	5x69	class-b1_on	35	0	No	No	Yes	No	8	8
131	3x41	4x56	class-b1_on	25	0	No	No	No	No	6	5
132	4x67	5x40	class-b1_on	30	0	No	No	Yes	Yes	3	4
133	5x64	5x68	class-b1_on	12	0	No	No	No	No	9	9
134	1x38	7x39	class-b1_on	20.0417	0	No	No	No	No	6	5
135	6x29	6x30	class-b1_on	34	0	Yes	No	No	No	5	6
136	6x25	6x28	class-b1_on	27.5	0	No	No	No	No	4	7
137	1x26	Lig	class-b1_on	15	0	No	No	Yes	No	0	0
138	4x51	4x54	class-b1_on	6.875	0	No	No	No	No	6	3
139	2x63	3x28	class-b1_on	27.5	0	No	No	No	No	4	7
140	5x69	6x33	class-b1_on	17.3333	0	Yes	No	No	Yes	8	9
141	8x56	8x60	class-b1_on	22	0	No	No	No	No	7	7
142	6x26	6x29	class-b1_on	24.5	0	No	No	Yes	No	5	5
143	4x62	4x66	class-b1_on	1.875	0	No	No	No	No	4	3
144	2x67	E1	class-b1_on	20	0	No	No	Yes	Yes	3	3
145	4x39	I2	class-b1_on	17.4167	0	No	No	Yes	Yes	6	7
146	4x59	5x421	class-b1_on	2	0	No	No	No	No	5	8
147	3x27	3x31	class-b1_on	10	0	No	No	No	No	4	5
148	1x36	2x62	class-b1_on	25	0	Yes	No	No	No	5	3
149	1x24	1x27	class-b1_on	22	0	No	No	No	No	0	0
150	8x47	8x48	class-b1_on	0.208333	0	No	No	No	No	9	6
151	4x41	4x45	class-b1_on	20.2083	0	No	No	No	No	5	2
152	1x41	1x45	class-b1_on	0	0	No	No	No	No	5	5
153	1x22	Lig	class-b1_on	17	0	No	No	Yes	No	0	0
154	4x38	4x41	class-b1_on	20.8333	0	No	No	No	No	7	5
155	1x30	1x34	class-b1_on	15	0	No	No	No	No	2	4
156	4x55	4x56	class-b1_on	5	0	No	No	No	No	4	5
157	4x44	4x48	class-b1_on	14	0	No	No	No	No	4	3
158	2x59	3x28	class-b1_on	5.20833	0	No	No	No	No	5	7
159	7x27	E3	class-b1_on	10	0	No	No	Yes	Yes	4	4
160	6x30	6x34	class-b1_on	20	0	No	No	No	No	6	8
161	8x55	8x58	class-b1_on	10.2083	0	No	No	Yes	No	6	5
162	6x27	6x31	class-b1_on	10	0	No	No	No	No	5	7
163	1x23	Lig	class-b1_on	7	0	No	No	Yes	No	0	0
164	6x55	E3	class-b1_on	5.625	0	No	No	Yes	Yes	7	4
165	5x52	6x49	class-b1_on	0	0	No	No	No	No	4	6
166	6x28	I3	class-b1_on	5.625	0	No	No	No	Yes	7	0
167	6x56	Lig	class-b1_on	5	0	No	No	Yes	No	0	0
168	2x38	4x40	class-b1_on	7	0	Yes	No	No	No	7	5
169	7x28	E3	class-b1_on	10	0	No	No	Yes	Yes	2	4
170	1x19	NT	class-b1_on	10	0	No	No	Yes	Yes	0	5
171	5x67	5x71	class-b1_on	0	0	No	No	No	No	7	7
172	1x37	1x40	class-b1_on	0	0	No	No	No	No	4	7
173	1x54	1x55	class-b1_on	0	0	No	No	No	No	6	2
174	8x63	8x67	class-b1_on	0	0	No	No	No	No	4	0
175	1x45	1x48	class-b1_on	0	0	No	No	No	No	5	3
176	8x59	8x63	class-b1_on	0.208333	0	No	No	No	No	4	4
177	8x61	8x64	class-b1_on	4.5	0	No	No	No	No	4	0
178	8x66	8x67	class-b1_on	0	0	No	No	No	No	0	0
179	8x61	8x65	class-b1_on	0	0	No	No	No	No	4	0
180	2x69	E1	class-b1_on	1.45833	0	No	No	Yes	Yes	4	3
181	5x73	6x29	class-b1_on	0.208333	0	No	No	Yes	No	0	5
182	E2	Lig	Shared	100	20	Yes	Yes	Yes	No	5	0
183	NT	NT	Shared	100	100	Yes	Yes	Yes	Yes	5	5
184	1x35	7x35	Shared	100	100	No	No	No	Yes	6	6
185	1x42	7x43	Shared	100	40	No	No	No	No	8	7
186	1x43	2x54	Shared	100	100	Yes	No	No	No	7	7
187	1x49	7x47	Shared	100	100	No	No	No	No	7	7
188	1x49	7x50	Shared	100	100	No	No	No	Yes	7	8
189	1x50	2x47	Shared	100	40	Yes	Yes	No	No	9	8
190	1x51	2x51	Shared	100	70	No	No	No	No	3	7
191	1x53	7x54	Shared	100	100	No	No	No	No	9	9
192	1x57	2x40	Shared	100	100	No	No	Yes	Yes	8	9
193	1x57	2x44	Shared	100	100	No	No	No	No	8	6
194	1x58	2x44	Shared	100	43.3333	No	No	No	No	3	6
195	1x60	8x53	Shared	100	100	Yes	Yes	No	No	7	8
196	1x60	8x57	Shared	100	40	Yes	Yes	No	No	7	5
197	8x53	I1x49	Shared	100	100	No	No	No	No	8	7
198	8x49	I1x50	Shared	100	50	No	No	No	Yes	9	9
199	2x38	3x49	Shared	100	100	Yes	No	Yes	No	7	8
200	2x38	4x43	Shared	100	100	Yes	No	No	No	7	6
201	2x39	2x43	Shared	100	100	No	No	No	Yes	9	9
202	2x42	3x46	Shared	100	100	No	No	Yes	No	8	9
203	2x43	3x46	Shared	100	100	No	Yes	Yes	No	9	9
204	2x45	3x42	Shared	100	100	No	No	Yes	Yes	9	9
205	2x50	3x39	Shared	100	100	Yes	No	No	No	8	9
206	2x50	7x45	Shared	100	100	Yes	No	Yes	No	8	9
207	2x52	3x35	Shared	100	100	No	No	Yes	No	7	5
208	2x53	3x36	Shared	100	100	No	No	No	No	8	6
209	E1	E1	Shared	100	100	Yes	Yes	Yes	Yes	3	3
210	3x25	E2x50	Shared	100	100	No	No	No	No	9	9
211	3x26	E2	Shared	100	43.3333	No	No	Yes	Yes	8	5
212	3x33	5x43	Shared	100	100	Yes	Yes	No	No	7	7
213	3x34	4x53	Shared	100	100	Yes	Yes	No	Yes	9	9
214	3x34	4x54	Shared	100	100	Yes	Yes	No	No	9	3
215	3x38	4x50	Shared	100	100	No	No	No	Yes	8	9
216	3x40	5x47	Shared	100	100	No	No	No	No	8	7
217	3x40	6x48	Shared	100	100	No	No	Yes	Yes	8	8
218	3x41	4x53	Shared	100	100	No	No	No	Yes	6	9
219	3x42	3x45	Shared	100	100	Yes	Yes	No	No	9	8
220	3x42	4x491	Shared	100	100	Yes	Yes	No	No	9	9
221	3x42	4x50	Shared	100	100	Yes	Yes	No	Yes	9	9
222	3x44	5x50	Shared	100	100	Yes	No	No	No	8	7
223	3x44	5x53	Shared	100	20	Yes	No	No	No	8	6
224	3x46	6x43	Shared	100	100	Yes	No	No	No	9	9
225	3x49	3x53	Shared	100	100	Yes	No	No	No	8	8
226	3x50	5x61	Shared	100	100	No	No	No	No	9	9
227	3x51	5x57	Shared	100	100	No	No	No	No	8	8
228	4x42	I2	Shared	100	100	No	Yes	Yes	Yes	5	7
229	E2	E2	Shared	100	100	Yes	Yes	Yes	Yes	5	5
230	5x41	5x44	Shared	100	100	Yes	No	No	No	6	6
231	5x54	6x44	Shared	100	100	No	No	Yes	No	9	9
232	5x55	5x59	Shared	100	20	No	No	No	No	6	5
233	5x58	5x62	Shared	100	100	Yes	Yes	No	No	9	7
234	5x58	6x40	Shared	100	100	Yes	Yes	No	No	9	9
235	5x58	6x44	Shared	100	53.3333	Yes	Yes	Yes	No	9	9
236	5x58	6x46	Shared	100	100	Yes	Yes	No	No	9	7
237	6x39	7x52	Shared	100	100	No	No	No	Yes	8	8
238	6x41	6x46	Shared	100	100	No	No	No	No	8	7
239	6x42	7x48	Shared	100	100	No	No	No	No	9	5
240	6x43	7x53	Shared	100	100	No	No	No	No	9	8
241	6x47	7x40	Shared	100	100	Yes	No	No	No	8	6
242	6x48	7x41	Shared	100	100	Yes	Yes	No	No	8	6
243	6x51	7x37	Shared	100	100	No	No	No	Yes	7	8
244	E3	E3	Shared	100	100	Yes	Yes	Yes	Yes	4	4
245	7x47	7x51	Shared	100	53.3333	No	No	No	No	7	6
246	8x47	8x50	Shared	100	100	No	No	No	No	9	9
247	2x45	4x47	Shared	100	100	No	No	No	No	9	5
248	2x57	3x32	Shared	100	100	Yes	No	Yes	No	7	6
249	3x34	3x35	Shared	100	100	Yes	Yes	Yes	No	9	5
250	3x51	3x55	Shared	100	100	No	No	No	No	8	6
251	6x48	7x45	Shared	100	100	Yes	Yes	Yes	No	8	9
252	I2	I2	Shared	100	100	Yes	Yes	Yes	Yes	7	7
253	I1x48	I1x51	Shared	70	20	No	No	No	No	8	7
254	1x45	7x47	Shared	67.0833	36.6667	No	No	No	No	5	7
255	3x34	4x50	Shared	52	100	Yes	Yes	No	Yes	9	9
256	5x45	5x46	Shared	78.375	60	No	No	No	No	4	8
257	3x54	5x61	Shared	54.0833	20	No	No	No	No	8	9
258	2x56	3x32	Shared	72.5	100	No	No	Yes	No	6	6
259	5x51	6x49	Shared	45.8333	40	No	No	No	No	7	6
260	1x36	1x40	Shared	55	100	Yes	No	No	No	5	7
261	2x37	2x40	Shared	47	16.6667	No	No	Yes	Yes	8	9
262	1x31	7x35	Shared	50	100	No	No	No	Yes	4	6
263	2x41	I1x51	Shared	50	40	No	No	No	No	6	7
264	3x37	4x53	Shared	66	100	No	Yes	No	Yes	6	9
265	1x50	2x51	Shared	56	100	Yes	Yes	No	No	9	7
266	1x47	2x54	Shared	50	100	No	No	No	No	7	7
267	3x43	7x45	Shared	47.8333	100	No	No	Yes	No	9	9
268	8x53	8x56	Shared	42	3.33333	No	No	No	No	8	7
269	1x50	2x50	Shared	52	100	Yes	Yes	Yes	No	9	8
270	3x22	3x24	Shared	40	20	No	No	No	Yes	0	3
271	2x40	I1x50	Shared	39.0833	100	Yes	Yes	No	Yes	9	9
272	2x60	3x28	Shared	45.8333	100	No	No	No	No	6	7
273	5x62	6x37	Shared	60	20	No	No	No	No	7	9
274	2x41	4x43	Shared	55	100	No	No	No	No	6	6
275	3x56	I2	Shared	33.875	100	No	No	Yes	Yes	5	7
276	3x54	5x64	Shared	42	30	No	No	No	No	8	9
277	8x51	8x55	Shared	27.2917	16.6667	No	No	No	No	7	6
278	1x60	I1x50	Shared	50	100	Yes	Yes	No	Yes	7	9
279	3x45	4x49	Shared	35	100	No	No	No	No	8	6
280	5x69	6x29	Shared	50	100	Yes	No	Yes	No	8	5
281	3x52	I2	Shared	33.3333	100	No	No	Yes	Yes	7	7
282	1x34	7x35	Shared	40.625	40	No	No	No	Yes	4	6
283	1x60	8x54	Shared	22	100	Yes	Yes	No	Yes	7	5
284	2x48	2x52	Shared	22	40	No	No	No	No	3	7
285	5x65	6x36	Shared	7.83333	26.6667	No	No	No	No	8	9
286	5x48	6x52	Shared	30	100	No	No	No	No	4	6
287	5x66	6x33	Shared	30	60	No	No	No	Yes	6	9
288	4x42	4x45	Shared	35	40	No	Yes	No	No	5	2
289	4x44	4x45	Shared	30	40	No	No	No	No	4	2
290	1x47	2x55	Shared	9.16667	100	No	No	No	No	7	3
291	1x59	1x60	Shared	24.1667	100	No	No	Yes	Yes	1	7
292	7x52	7x56	Shared	25.2083	36.6667	No	Yes	No	No	8	6
293	6x34	6x38	Shared	4	13.3333	No	No	No	No	8	8
294	6x28	6x31	Shared	20.2083	33.3333	No	No	No	No	7	7
295	4x54	4x58	Shared	15.2083	6.66667	No	No	No	No	3	3
296	7x32	7x36	Shared	20	36.6667	No	No	No	No	4	4
297	3x23	3x27	Shared	10.8333	0	No	No	No	No	3	4
298	5x67	5x68	Shared	5	20	No	No	No	No	7	9
299	5x49	5x53	Shared	12.5	40	No	No	No	No	4	6
300	8x48	8x51	Shared	2	26.6667	No	No	No	No	6	7
301	8x52	8x56	Shared	6.04167	20	No	No	No	No	4	7
302	2x66	E1	Shared	5	20	No	No	Yes	Yes	3	3
303	3x21	E1	Shared	0	20	No	No	Yes	Yes	0	3
304	5x72	I3	Shared	1.66667	50	No	No	No	Yes	6	0
305	1x40	2x61	class-b2_on	0	100	No	No	No	No	7	7
306	1x43	2x58	class-b2_on	0	100	Yes	No	No	No	7	7
307	1x46	2x54	class-b2_on	0	100	No	No	No	No	9	7
308	1x50	7x46	class-b2_on	0	100	Yes	Yes	No	No	9	9
309	1x52	7x50	class-b2_on	0	100	No	No	No	Yes	4	8
310	1x53	7x50	class-b2_on	0	100	No	No	No	Yes	9	8
311	1x54	2x48	class-b2_on	0	100	No	No	No	No	6	3
312	1x56	8x54	class-b2_on	0	100	No	No	No	Yes	8	5
313	1x57	2x43	class-b2_on	0	100	No	No	No	Yes	8	9
314	2x38	4x42	class-b2_on	0	100	Yes	No	No	Yes	7	5
315	2x39	3x49	class-b2_on	0	100	No	No	Yes	No	9	8
316	2x42	3x42	class-b2_on	0	100	No	No	Yes	Yes	8	9
317	2x43	6x43	class-b2_on	0	100	No	Yes	No	No	9	9
318	2x45	4x50	class-b2_on	0	100	No	No	No	Yes	9	9
319	2x46	3x42	class-b2_on	0	100	No	No	Yes	Yes	9	9
320	2x46	3x43	class-b2_on	0	100	No	No	No	No	9	9
321	2x56	3x31	class-b2_on	0	100	No	No	No	No	6	5
322	3x29	E2	class-b2_on	0	100	No	No	Yes	Yes	5	5
323	3x30	E2	class-b2_on	0	100	No	No	Yes	Yes	5	5
324	3x32	E2x51	class-b2_on	0	100	Yes	No	Yes	Yes	6	8
325	3x33	3x37	class-b2_on	0	100	Yes	Yes	No	Yes	7	6
326	3x33	4x57	class-b2_on	0	100	Yes	Yes	No	No	7	6
327	3x33	E2	class-b2_on	0	100	Yes	Yes	Yes	Yes	7	5
328	3x33	E2x52	class-b2_on	0	100	Yes	Yes	No	Yes	7	5
329	3x37	4x56	class-b2_on	0	100	No	Yes	No	No	6	5
330	3x37	5x46	class-b2_on	0	100	No	Yes	No	No	6	8
331	3x38	4x53	class-b2_on	0	100	No	No	No	Yes	8	9
332	3x45	4x46	class-b2_on	0	100	No	No	No	No	8	7
333	4x42	4x46	class-b2_on	0	100	No	Yes	No	No	5	7
334	4x60	E2	class-b2_on	0	100	Yes	No	Yes	Yes	8	5
335	4x61	E2	class-b2_on	0	100	No	No	Yes	Yes	5	5
336	4x64	E2	class-b2_on	0	100	Yes	No	Yes	Yes	8	5
337	5x39	E2	class-b2_on	0	100	No	No	Yes	Yes	3	5
338	E2	E2x52	class-b2_on	0	100	Yes	Yes	No	Yes	5	5
339	5x40	E2x51	class-b2_on	0	100	Yes	Yes	Yes	Yes	4	8
340	5x43	E2x51	class-b2_on	0	100	No	No	Yes	Yes	7	8
341	5x39	E2x52	class-b2_on	0	100	No	No	No	Yes	3	5
342	5x40	E2x52	class-b2_on	0	100	Yes	Yes	No	Yes	4	5
343	5x40	5x44	class-b2_on	0	100	Yes	Yes	No	No	4	6
344	5x58	6x41	class-b2_on	0	100	Yes	Yes	No	No	9	8
345	6x38	7x52	class-b2_on	0	100	No	No	No	Yes	8	8
346	6x47	7x41	class-b2_on	0	100	Yes	No	No	No	8	6
347	6x48	7x37	class-b2_on	0	100	Yes	Yes	No	Yes	8	8
348	6x50	7x36	class-b2_on	0	100	No	No	No	No	6	4
349	6x50	7x40	class-b2_on	0	100	No	No	No	No	6	6
350	6x53	7x33	class-b2_on	0	100	No	No	No	No	4	7
351	7x37	7x41	class-b2_on	0	100	No	Yes	No	No	8	6
352	7x43	7x48	class-b2_on	0	100	No	No	No	No	7	5
353	7x50	7x54	class-b2_on	0	100	No	Yes	No	No	8	9
354	7x50	7x55	class-b2_on	0	100	No	Yes	No	No	8	8
355	7x51	7x52	class-b2_on	0	100	No	No	No	Yes	6	8
356	1x32	NT	class-b2_on	0	100	No	No	Yes	Yes	5	5
357	1x36	NT	class-b2_on	0	100	Yes	No	Yes	Yes	5	5
358	1x39	NT	class-b2_on	0	100	Yes	No	Yes	Yes	7	5
359	2x57	NT	class-b2_on	0	100	Yes	No	Yes	Yes	7	5
360	E2	NT	class-b2_on	0	100	Yes	Yes	Yes	Yes	5	5
361	1x35	NT	class-b2_on	0	100	No	No	Yes	Yes	6	5
362	1x43	NT	class-b2_on	0	100	Yes	No	Yes	Yes	7	5
363	6x48	NT	class-b2_on	0	100	Yes	Yes	Yes	Yes	8	5
364	7x37	NT	class-b2_on	0	100	No	Yes	Yes	Yes	8	5
365	7x42	NT	class-b2_on	0	100	No	No	Yes	Yes	9	5
366	7x34	NT	class-b2_on	0	100	No	No	Yes	Yes	5	5
367	E2x51	NT	class-b2_on	0	100	Yes	Yes	Yes	Yes	8	5
368	3x36	NT	class-b2_on	0	100	No	No	Yes	Yes	6	5
369	5x44	NT	class-b2_on	0	100	No	No	Yes	Yes	6	5
370	5x40	NT	class-b2_on	0	100	Yes	Yes	Yes	Yes	4	5
371	E3	NT	class-b2_on	0	100	Yes	Yes	Yes	Yes	4	5
372	1x30	NT	class-b2_on	0	100	No	No	Yes	Yes	2	5
373	E2x51	E2x52	class-b2_on	0	100	Yes	Yes	No	Yes	8	5
374	I3	I3	class-b2_on	0	100	No	Yes	No	Yes	0	0
375	5x69	I3	class-b2_on	0	100	Yes	No	No	Yes	8	0
376	1x33	1x34	class-b2_on	0	100	No	No	No	No	3	4
377	2x57	E1	class-b2_on	0	100	Yes	No	Yes	Yes	7	3
378	1x29	E2	class-b2_on	0	100	No	No	Yes	Yes	2	5
379	5x63	5x64	class-b2_on	0	60	No	No	No	No	7	9
380	7x30	7x33	class-b2_on	0	26.6667	No	No	No	No	5	7
381	8x50	8x54	class-b2_on	0	46.6667	No	No	No	Yes	9	5
382	5x55	6x46	class-b2_on	0	46.6667	No	No	No	No	6	7
383	3x48	3x52	class-b2_on	0	30	No	No	No	No	6	7
384	2x49	3x38	class-b2_on	0	60	No	No	No	No	9	8
385	1x42	7x42	class-b2_on	0	50	No	No	No	No	8	9
386	1x53	2x47	class-b2_on	0	40	No	No	No	No	9	8
387	3x51	3x56	class-b2_on	0	40	No	No	No	No	8	5
388	7x31	7x35	class-b2_on	0	40	No	No	No	Yes	4	6
389	1x37	1x41	class-b2_on	0	30	No	No	No	No	4	5
390	3x33	5x42	class-b2_on	0	46.6667	Yes	Yes	No	No	7	7
391	3x43	6x45	class-b2_on	0	26.6667	No	No	No	No	9	9
392	7x39	7x40	class-b2_on	0	33.3333	No	No	No	No	5	6
393	4x49	4x52	class-b2_on	0	36.6667	No	No	No	No	6	3
394	7x38	NT	class-b2_on	0	46.6667	No	No	Yes	Yes	7	5
395	7x49	7x53	class-b2_on	0	40	No	No	No	No	9	8
396	3x47	5x54	class-b2_on	0	26.6667	No	No	No	No	8	9
397	E1	E2x50	class-b2_on	0	46.6667	Yes	Yes	No	No	3	9
398	7x33	E3	class-b2_on	0	46.6667	No	No	Yes	Yes	7	4
399	5x50	5x54	class-b2_on	0	16.6667	No	No	No	No	7	9
400	5x63	5x67	class-b2_on	0	46.6667	No	No	No	No	7	7
401	5x38	E2	class-b2_on	0	20	No	No	Yes	Yes	5	5
402	3x40	5x50	class-b2_on	0	20	No	No	No	No	8	7
403	3x50	5x57	class-b2_on	0	40	No	No	No	No	9	8
404	2x60	E2	class-b2_on	0	20	No	No	Yes	Yes	6	5
405	2x35	3x53	class-b2_on	0	20	No	No	No	No	0	8
406	5x47	5x51	class-b2_on	0	20	No	No	No	No	7	7
407	3x55	5x60	class-b2_on	0	16.6667	No	No	No	No	6	8
408	6x54	7x34	class-b2_on	0	20	No	No	No	No	5	5
409	3x21	3x24	class-b2_on	0	40	No	No	No	Yes	0	3
410	5x65	6x33	class-b2_on	0	20	No	No	No	Yes	8	9
411	1x41	1x42	class-b2_on	0	30	No	No	No	No	5	8
412	5x68	5x71	class-b2_on	0	20	No	No	No	No	9	7
413	1x38	7x38	class-b2_on	0	33.3333	No	No	No	No	6	7
414	5x62	6x33	class-b2_on	0	40	No	No	No	Yes	7	9
415	6x55	NT	class-b2_on	0	40	No	No	Yes	Yes	7	5
416	6x35	7x56	class-b2_on	0	16.6667	No	No	No	No	8	6
417	6x29	6x33	class-b2_on	0	30	Yes	No	No	Yes	5	9
418	2x59	2x60	class-b2_on	0	40	No	No	No	No	5	6
419	1x48	1x52	class-b2_on	0	20	No	No	No	No	3	4
420	6x57	7x30	class-b2_on	0	20	No	No	No	No	0	5
421	4x51	4x53	class-b2_on	0	6.66667	No	No	No	Yes	6	9
422	6x26	6x27	class-b2_on	0	20	No	No	No	No	5	5
423	1x28	NT	class-b2_on	0	20	No	No	Yes	Yes	0	5
424	4x41	I2	class-b2_on	0	26.6667	No	No	Yes	Yes	5	7
425	5x48	5x52	class-b2_on	0	26.6667	No	No	No	No	4	4
426	5x51	6x52	class-b2_on	0	20	No	No	No	No	7	6
427	5x71	5x74	class-b2_on	0	20	No	No	No	No	7	0
428	7x57	8x49	class-b2_on	0	20	No	No	No	No	0	9
429	2x37	4x39	class-b2_on	0	20	No	No	No	No	8	6
430	2x63	3x24	class-b2_on	0	16.6667	No	No	No	Yes	4	3
431	4x59	4x63	class-b2_on	0	0	No	No	No	No	5	4
432	3x33	5x421	class-b2_on	0	20	Yes	Yes	No	No	7	8
433	2x34	4x39	class-b2_on	0	20	No	No	No	No	0	6
434	6x26	6x28	class-b2_on	0	20	No	No	No	No	5	7
435	8x54	8x58	class-b2_on	0	20	No	Yes	Yes	No	5	5
436	4x62	4x63	class-b2_on	0	0	No	No	No	No	4	4
437	4x55	4x59	class-b2_on	0	20	No	No	No	No	4	5
438	I1	I1x48	class-b2_on	0	20	No	No	No	No	0	8
439	4x38	4x40	class-b2_on	0	20	No	No	No	No	7	5
440	3x23	3x24	class-b2_on	0	20	No	No	No	Yes	3	3
441	1x55	1x59	class-b2_on	0	20	No	No	No	No	2	1
442	1x61	I1x50	class-b2_on	0	20	No	No	No	Yes	0	9
443	8x48	8x52	class-b2_on	0	26.6667	No	No	No	No	6	4
444	4x40	4x41	class-b2_on	0	20	No	No	No	No	5	5
445	6x30	6x33	class-b2_on	0	6.66667	No	No	No	Yes	6	9
446	5x65	6x32	class-b2_on	0	20	No	No	No	No	8	8
447	4x65	E2	class-b2_on	0	20	No	No	Yes	Yes	3	5
448	1x63	I1x50	class-b2_on	0	20	No	No	No	Yes	0	9
449	5x73	I3	class-b2_on	0	20	No	No	No	Yes	0	0
450	5x55	5x56	class-b2_on	0	20	No	No	No	No	6	5
451	8x55	8x59	class-b2_on	0	26.6667	No	No	No	No	6	4
452	5x37	Lig	class-b2_on	0	10	No	No	Yes	No	5	0
453	6x55	6x56	class-b2_on	0	20	No	No	No	No	7	0
454	1x41	1x44	class-b2_on	0	20	No	No	No	No	5	6
455	1x62	8x57	class-b2_on	0	20	No	No	No	No	0	5
456	4x45	4x48	class-b2_on	0	6.66667	No	No	No	No	2	3
457	2x61	2x62	class-b2_on	0	0	No	No	No	No	7	3
458	6x58	NT	class-b2_on	0	6.66667	No	No	Yes	Yes	0	5
459	4x63	4x64	class-b2_on	0	0	No	No	Yes	No	4	8
460	2x63	2x65	class-b2_on	0	6.66667	No	No	No	No	4	4
461	6x31	6x35	class-b2_on	0	6.66667	No	No	No	No	7	8
462	2x36	2x40	class-b2_on	0	6.66667	No	No	Yes	Yes	0	9
463	7x29	7x32	class-b2_on	0	0	No	No	No	No	3	4
464	2x33	2x36	class-b2_on	0	6.66667	No	No	No	No	0	0
465	5x70	6x29	class-b2_on	0	6.66667	No	No	Yes	No	6	5

Orange: nodes, hubs and links specific of class-b1_on network

Green: nodes, hubs and links shared by both networks

Purple: nodes, hubs and links specific of class-b2_on network

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Owner: the name of the network the hub belong to or "Shared" if the corresponding hub is present in both networks.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub in the corresponding network.

Num Of Links: the number of links of the corresponding hub in the corresponding network.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Owner	class-b1_on Avg Int. Strength	class-b2_on Avg Int. Strength	class-b1_on Num Of Links	class-b2_on Num Of Links	ConSurf
1	Lig	class-b1_on	100	6.66667	33	2	0
2	1x36	class-b1_on	20	0	5	2	5
3	1x39	class-b1_on	39.5833	0	6	1	7
4	1x43	class-b1_on	72.7917	20	5	3	7
5	2x38	class-b1_on	0	10	4	3	7
6	2x50	class-b1_on	56.125	0	6	3	8
7	2x57	class-b1_on	20	0	4	3	7
8	3x32	class-b1_on	25	0	4	3	6
9	3x35	class-b1_on	10	20	4	2	5
10	3x44	class-b1_on	10	0	4	2	8
11	3x46	class-b1_on	84.1667	26.6667	4	3	9
12	3x49	class-b1_on	59.1667	13.3333	5	3	8
13	4x60	class-b1_on	43	0	4	1	8
14	4x64	class-b1_on	33.3333	0	4	2	8
15	5x41	class-b1_on	44.375	0	4	1	6
16	5x69	class-b1_on	0	0	4	2	8
17	6x29	class-b1_on	0	0	5	3	5
18	6x44	class-b1_on	36	0	4	2	9
19	6x47	class-b1_on	30	10	4	2	8
20	7x45	class-b1_on	0	30	4	3	9
21	8x58	class-b1_on	0	0	4	1	5
22	NT	Shared	63.5	93.3333	6	23	5
23	1x50	Shared	0	20	4	4	9
24	1x60	Shared	0	26.6667	5	5	7
25	2x40	Shared	0	33.3333	4	4	9
26	E1	Shared	73.3333	40	10	6	3
27	3x33	Shared	14.1667	66.6667	4	7	7
28	3x34	Shared	10	40	5	4	9
29	3x42	Shared	90	96.6667	4	6	9
30	I2	Shared	40	20	8	6	7
31	E2	Shared	98	100	8	17	5
32	E2x51	Shared	30	83.3333	5	5	8
33	5x40	Shared	0	43.3333	4	4	4
34	5x58	Shared	40	0	4	5	9
35	6x48	Shared	68.3333	100	5	5	8
36	E3	Shared	40	40	8	4	4
37	I1x50	class-b2_on	0	0	3	5	9
38	2x43	class-b2_on	0	33.3333	3	4	9
39	3x24	class-b2_on	0	0	2	4	3
40	3x37	class-b2_on	0	13.3333	1	4	6
41	4x42	class-b2_on	0	20	2	4	5
42	4x50	class-b2_on	0	66.6667	3	4	9
43	4x53	class-b2_on	0	0	3	5	9
44	E2x52	class-b2_on	0	10	3	5	5
45	I3	class-b2_on	0	20	3	5	0
46	6x33	class-b2_on	0	0	2	5	9
47	7x35	class-b2_on	0	13.3333	3	4	6
48	7x37	class-b2_on	12.3333	73.3333	3	4	8
49	7x50	class-b2_on	0	53.3333	2	5	8
50	7x52	class-b2_on	0	13.3333	3	4	8
51	8x54	class-b2_on	0	20	1	4	5

Orange: nodes, hubs and links specific of class-b1_on network

Green: nodes, hubs and links shared by both networks

Purple: nodes, hubs and links specific of class-b2_on network

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Owner: the name of the network the link belong to or "Shared" if the corresponding link is present in both networks.

Recurrence: the relative Recurrence in the filtered pool of shortest paths.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Owner	class-b1_on Recurrence	class-b2_on Recurrence	class-b1_on Hub1?	class-b2_on Hub1?	class-b1_on Hub2?	class-b2_on Hub2?	ConSurf1	ConSurf2
1	1x43	2x57	class-b1_on	19.0894	0	Yes	No	Yes	No	7	7
2	2x53	3x36	class-b1_on	67.1264	1.96689	No	No	No	No	8	6
3	3x36	Lig	class-b1_on	74.0601	0	No	No	Yes	No	6	0
4	1x50	7x50	class-b1_on	14.3837	0	Yes	Yes	No	Yes	9	8
5	2x50	3x39	class-b1_on	96.5626	1.93859	Yes	No	No	No	8	9
6	2x53	3x39	class-b1_on	96.7012	0	No	No	No	No	8	9
7	2x39	2x40	class-b1_on	35.3962	0	No	No	Yes	Yes	9	9
8	2x46	3x46	class-b1_on	99.6847	0	No	No	Yes	No	9	9
9	2x46	2x50	class-b1_on	100	0	No	No	Yes	No	9	8
10	8x49	I1x50	class-b1_on	17.0761	3.05646	No	No	No	Yes	9	9
11	2x42	3x49	class-b1_on	21.4283	0	No	No	Yes	No	8	8
12	2x43	7x53	class-b1_on	25.1672	0	No	Yes	No	No	9	8
13	3x34	3x35	class-b1_on	33.1786	9.1057	Yes	Yes	Yes	No	9	5
14	2x56	3x35	class-b1_on	42.0978	0	No	No	Yes	No	6	5
15	2x56	3x32	class-b1_on	43.5601	7.84633	No	No	Yes	No	6	6
16	3x32	Lig	class-b1_on	27.6066	0	Yes	No	Yes	No	6	0
17	E2	Lig	class-b1_on	20.5066	4.07528	Yes	Yes	Yes	No	5	0
18	E2	E2x51	class-b1_on	10.9983	0	Yes	Yes	Yes	Yes	5	8
19	3x33	Lig	class-b1_on	12.3254	0	Yes	Yes	Yes	No	7	0
20	3x44	5x54	class-b1_on	13.6041	0	Yes	No	No	No	8	9
21	6x43	6x44	class-b1_on	33.8439	0	No	No	Yes	No	9	9
22	3x46	6x43	class-b1_on	47.9538	4.81109	Yes	No	No	No	9	9
23	3x49	I2	class-b1_on	11.182	0	Yes	No	Yes	Yes	8	7
24	7x52	7x53	class-b1_on	41.4152	0	No	Yes	No	No	8	8
25	6x43	7x53	class-b1_on	24.9142	3.79935	No	No	No	No	9	8
26	8x47	8x49	class-b1_on	15.9153	0	No	No	No	No	9	9
27	4x64	5x40	class-b1_on	17.589	0	Yes	No	Yes	Yes	8	4
28	6x32	6x35	class-b1_on	34.2216	0	No	No	No	No	8	8
29	6x35	6x39	class-b1_on	36.0962	0	No	No	No	No	8	8
30	6x39	7x52	class-b1_on	37.6694	1.35843	No	No	No	Yes	8	8
31	8x55	8x58	class-b1_on	10.0073	0	No	No	Yes	No	6	5
32	8x51	8x55	class-b1_on	11.2027	3.79935	No	No	No	No	7	6
33	8x48	8x51	class-b1_on	12.3913	6.03509	No	No	No	No	6	7
34	8x47	8x48	class-b1_on	13.5729	0	No	No	No	No	9	6
35	5x69	6x29	class-b1_on	21.4283	5.30635	Yes	No	Yes	No	8	5
36	5x69	6x32	class-b1_on	32.3331	0	Yes	No	No	No	8	8
37	6x29	I3	class-b1_on	10.3261	0	Yes	No	No	Yes	5	0
38	1x43	2x53	class-b1_on	30.6317	0	Yes	No	No	No	7	8
39	2x57	3x32	class-b1_on	16.9618	5.39125	Yes	No	Yes	No	7	6
40	1x49	7x50	Shared	13.2229	22.7819	No	No	No	Yes	7	8
41	1x50	2x50	Shared	18.9577	40.1585	Yes	Yes	Yes	No	9	8
42	1x49	7x47	Shared	12.0552	21.0202	No	No	No	No	7	7
43	2x39	2x43	Shared	36.4323	14.0158	No	No	No	Yes	9	9
44	2x43	3x46	Shared	50.5735	57.1176	No	Yes	Yes	No	9	9
45	1x60	I1x50	Shared	10.7142	34.4205	Yes	Yes	No	Yes	7	9
46	2x40	I1x50	Shared	27.9497	41.7292	Yes	Yes	No	Yes	9	9
47	2x42	3x46	Shared	22.5337	63.372	No	No	Yes	No	8	9
48	3x34	4x50	Shared	12.9977	26.836	Yes	Yes	No	Yes	9	9
49	3x34	4x53	Shared	12.9977	26.6874	Yes	Yes	No	Yes	9	9
50	5x54	6x44	Shared	14.7995	36.1752	No	No	Yes	No	9	9
51	5x58	6x44	Shared	18.1261	34.4347	Yes	Yes	Yes	No	9	9
52	1x35	NT	class-b2_on	0	11.016	No	No	Yes	Yes	6	5
53	1x43	NT	class-b2_on	0	11.3273	Yes	No	Yes	Yes	7	5
54	6x48	NT	class-b2_on	0	93.314	Yes	Yes	Yes	Yes	8	5
55	6x48	7x45	class-b2_on	5.84566	100	Yes	Yes	Yes	No	8	9
56	2x50	7x45	class-b2_on	8.9019	43.3281	Yes	No	Yes	No	8	9
57	1x50	2x47	class-b2_on	1.23358	33.6494	Yes	Yes	No	No	9	8
58	1x53	2x47	class-b2_on	0	31.9867	No	No	No	No	9	8
59	1x53	7x50	class-b2_on	0	29.0293	No	No	No	Yes	9	8
60	E2	NT	class-b2_on	0	45.9955	Yes	Yes	Yes	Yes	5	5
61	3x33	E2	class-b2_on	0	40.5405	Yes	Yes	Yes	Yes	7	5
62	3x33	3x37	class-b2_on	0	45.9389	Yes	Yes	No	Yes	7	6
63	3x37	4x53	class-b2_on	1.64593	46.4341	No	Yes	No	Yes	6	9
64	3x43	7x45	class-b2_on	1.10537	92.1041	No	No	Yes	No	9	9
65	2x46	3x43	class-b2_on	0	91.2127	No	No	No	No	9	9
66	2x46	3x42	class-b2_on	0	90.8306	No	No	Yes	Yes	9	9
67	2x42	3x42	class-b2_on	0	65.0064	No	No	Yes	Yes	8	9
68	1x57	2x43	class-b2_on	0	55.8724	No	No	No	Yes	8	9
69	1x57	2x40	class-b2_on	6.21643	50.8985	No	No	Yes	Yes	8	9
70	1x60	8x53	class-b2_on	6.21643	16.2799	Yes	Yes	No	No	7	8
71	3x42	3x45	class-b2_on	3.2884	57.535	Yes	Yes	No	No	9	8
72	3x45	4x46	class-b2_on	0	52.1721	No	No	No	No	8	7
73	4x42	4x46	class-b2_on	0	51.2735	No	Yes	No	No	5	7
74	2x38	4x42	class-b2_on	0	20.5604	Yes	No	No	Yes	7	5
75	2x39	3x49	class-b2_on	0	12.2471	No	No	Yes	No	9	8
76	2x38	3x49	class-b2_on	6.88174	11.7023	Yes	No	Yes	No	7	8
77	2x38	4x43	class-b2_on	4.90315	10.3085	Yes	No	No	No	7	6
78	3x38	4x53	class-b2_on	0	21.1688	No	No	No	Yes	8	9
79	3x38	4x50	class-b2_on	1.64593	21.2113	No	No	No	Yes	8	9
80	3x42	4x50	class-b2_on	9.78897	46.5261	Yes	Yes	No	Yes	9	9
81	2x57	NT	class-b2_on	0	23.6663	Yes	No	Yes	Yes	7	5
82	2x57	E1	class-b2_on	0	17.9638	Yes	No	Yes	Yes	7	3
83	3x40	6x48	class-b2_on	8.33362	56.6436	No	No	Yes	Yes	8	8
84	3x40	5x47	class-b2_on	1.10884	11.5325	No	No	No	No	8	7
85	3x40	5x50	class-b2_on	0	45.8964	No	No	No	No	8	7
86	4x42	I2	class-b2_on	6.85748	36.1893	No	Yes	Yes	Yes	5	7
87	3x56	I2	class-b2_on	1.23358	26.4044	No	No	Yes	Yes	5	7
88	3x51	3x56	class-b2_on	0	25.0177	No	No	No	No	8	5
89	3x51	5x57	class-b2_on	6.28573	19.3222	No	No	No	No	8	8
90	3x50	5x57	class-b2_on	0	17.8152	No	No	No	No	9	8
91	3x50	5x61	class-b2_on	1.26824	15.6644	No	No	No	No	9	9
92	4x64	E2	class-b2_on	0	15.5936	Yes	No	Yes	Yes	8	5
93	5x50	5x54	class-b2_on	0	39.4722	No	No	No	No	7	9
94	5x58	5x62	class-b2_on	2.53301	22.223	Yes	Yes	No	No	9	7
95	7x47	7x51	class-b2_on	7.31488	17.4544	No	No	No	No	7	6
96	7x51	7x52	class-b2_on	0	15.6502	No	No	No	Yes	6	8
97	7x42	NT	class-b2_on	0	15.1054	No	No	Yes	Yes	9	5
98	1x42	7x42	class-b2_on	0	13.5135	No	No	No	No	8	9
99	6x48	7x41	class-b2_on	1.10884	14.6314	Yes	Yes	No	No	8	6
100	6x47	7x41	class-b2_on	0	18.0275	Yes	No	No	No	8	6
101	6x47	7x40	class-b2_on	3.41661	15.3743	Yes	No	No	No	8	6
102	6x50	7x40	class-b2_on	0	10.0255	No	No	No	No	6	6
103	5x62	6x33	class-b2_on	0	19.117	No	No	No	Yes	7	9
104	3x54	5x61	class-b2_on	6.06397	14.1432	No	No	No	No	8	9
105	3x54	5x64	class-b2_on	4.81999	11.957	No	No	No	No	8	9
106	8x53	8x56	class-b2_on	3.74926	12.6574	No	No	No	No	8	7
107	8x52	8x56	class-b2_on	1.25437	10.4641	No	No	No	No	4	7
108	3x21	E1	class-b2_on	0.828165	11.7164	No	No	Yes	Yes	0	3
109	3x21	3x24	class-b2_on	0	10.4146	No	No	No	Yes	0	3
110	4x63	4x64	class-b2_on	0	12.5018	No	No	Yes	No	4	8

Here, those paths that begin and end at given residue pair(s) or that pass through a residue are used to generate a novel metapath. Such a path filtering is particularly recommended if some information on allosteric residues is available. The selection syntax for a residue pair ("Pairs") is C:C:c534,A:A:?600 (the lower-case "c" stands for cytosine and "?" indicates any non standard amino acid or nucleotide residue). Selection of more than one apical residue pair has the following syntax: C:C:c534,A:A:?600,C:C:c534,A:A:E41. Only one residue can be selected as a tail ("Tail"). For midway residue(s), each residue must be separated by a comma as well e.g. A:A:?600,A:A:E41.

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Node1	Node2	Owner	Net1LinkStrength	Net2LinkStrength	Comm1	Comm2	Node1Shell	Node2Shell
3x33	Lig	class-b1_on	5.77305	0	1	1	1	0
3x36	Lig	class-b1_on	8.73457	0	1	1	1	0
5x41	Lig	class-b1_on	5.9845	0	1	0	1	0
7x34	Lig	class-b1_on	7.04403	0	0	1	1	0
7x37	Lig	class-b1_on	7.73524	0	1	1	1	0
2x57	Lig	class-b1_on	4.35631	0	1	1	1	0
3x32	Lig	class-b1_on	7.90329	0	1	0	1	0
7x38	Lig	class-b1_on	9.55991	0	1	1	1	0
E2	Lig	Shared	16.7358	1.847	1	1	1	0
E3	Lig	class-b1_on	4.3078	0	1	1	1	0
7x30	Lig	class-b1_on	4.26879	0	0	0	1	0
1x32	Lig	class-b1_on	14.9813	0	0	0	1	0
1x36	Lig	class-b1_on	5.64385	0	1	1	1	0
1x39	Lig	class-b1_on	4.58	0	1	0	1	0
2x60	Lig	class-b1_on	6.07906	0	1	1	1	0
E2x52	Lig	class-b1_on	10.496	0	1	1	1	0
1x29	Lig	class-b1_on	7.64669	0	1	0	1	0
Lig	NT	class-b1_on	77.5284	0	1	1	0	1
E1	Lig	class-b1_on	19.7614	0	1	1	1	0
NT	NT	Shared	427.278	20.4493	1	1	1	1
E1	NT	class-b1_on	8.27625	0	1	1	1	1
1x35	7x38	class-b1_on	5.11883	0	0	1	2	1
1x36	1x39	class-b1_on	3.95804	0	1	1	1	1
1x36	2x61	class-b1_on	4.6594	0	1	1	1	2
1x39	1x43	class-b1_on	4.27141	0	1	0	1	2
1x39	2x61	class-b1_on	4.15332	0	1	0	1	2
1x39	7x38	class-b1_on	4.54095	0	1	0	1	1
1x39	7x42	class-b1_on	5.48747	0	1	0	1	2
1x43	2x53	class-b1_on	4.55524	0	1	1	2	2
1x43	2x57	class-b1_on	11.0037	0	1	1	2	1
1x43	7x42	class-b1_on	7.01441	0	1	1	2	2
2x53	3x36	Shared	7.2109	5.95933	0	0	2	1
2x57	2x61	class-b1_on	4.75263	0	1	1	1	2
2x60	3x32	class-b1_on	8.72332	0	1	1	1	1
E1	E1	Shared	19.2701	8.24267	1	1	1	1
3x26	E2	Shared	6.4667	2.882	1	0	2	1
3x26	E2x51	class-b1_on	23.7585	0	1	0	2	2
3x33	4x60	class-b1_on	6.52858	0	1	1	1	2
3x33	5x43	Shared	7.53317	4.60167	1	1	1	2
3x36	3x40	class-b1_on	4.32113	0	1	1	1	2
3x40	6x48	Shared	10.6535	14.0977	0	0	2	2
4x60	4x64	class-b1_on	9.39427	0	1	0	2	2
4x60	5x421	class-b1_on	4.04346	0	1	0	2	2
4x60	5x43	class-b1_on	9.94491	0	1	0	2	2
4x64	4x68	class-b1_on	4.91516	0	0	1	2	2
4x64	E2x51	class-b1_on	17.8067	0	0	1	2	2
4x68	E2	class-b1_on	11.0621	0	1	0	2	1
E2	E2x51	class-b1_on	4.96277	0	1	1	1	2
E2	E2	Shared	12.3872	39.649	1	1	1	1
5x41	E2	class-b1_on	7.84191	0	1	0	1	1
5x41	5x43	class-b1_on	4.10469	0	1	0	1	2
5x41	5x44	Shared	7.66404	6.14233	1	0	1	1
5x42	5x44	class-b1_on	6.7566	0	0	0	2	1
6x48	7x41	Shared	5.10473	20.1893	3	1	2	2
6x51	7x33	class-b1_on	6.26625	0	1	0	2	2
6x51	7x37	Shared	4.50075	4.97033	1	0	2	1
E3	E3	Shared	5.55099	5.90367	1	1	1	1
7x33	7x37	class-b1_on	7.98596	0	1	1	2	1
2x57	3x32	Shared	4.9898	3.67033	1	1	1	1
E1	E2	class-b1_on	6.52319	0	1	1	1	1
4x64	5x40	class-b1_on	4.31973	0	0	1	2	2
1x29	1x33	class-b1_on	4.08389	0	1	0	1	2
5x44	Lig	class-b1_on	9.52363	0	1	1	1	0
1x25	Lig	class-b1_on	4.40587	0	0	0	1	0
2x56	3x32	Shared	3.59667	4.02867	0	0	2	1
1x36	1x40	Shared	3.56308	6.01433	1	1	1	2
3x29	3x33	class-b1_on	3.31609	0	0	0	2	1
5x51	6x48	class-b1_on	3.21362	0	0	0	2	2
2x64	E2x52	class-b1_on	3.19395	0	0	0	2	1
E2x50	E2x52	class-b1_on	3.17497	0	0	1	2	1
2x60	3x28	Shared	3.13687	3.86033	1	1	1	2
7x29	E3	class-b1_on	3.12093	0	0	0	2	1
1x28	Lig	class-b1_on	2.91273	0	0	0	1	0
2x65	Lig	class-b1_on	2.76299	0	0	0	1	0
4x65	E2x51	class-b1_on	2.7163	0	0	0	2	2
5x37	5x40	class-b1_on	2.6604	0	0	0	1	2
3x30	4x61	class-b1_on	2.45375	0	0	0	2	2
6x54	E3	class-b1_on	2.43991	0	0	0	2	1
4x61	E2x51	class-b1_on	2.38344	0	0	0	2	2
1x24	NT	class-b1_on	2.3465	0	1	0	2	1
6x53	Lig	class-b1_on	2.3395	0	0	0	1	0
5x39	5x42	class-b1_on	2.33268	0	0	1	2	2
5x48	6x52	Shared	2.11658	3.321	0	0	2	1
2x68	Lig	class-b1_on	2.1165	0	0	0	1	0
1x21	Lig	class-b1_on	2.1058	0	0	0	1	0
6x52	Lig	class-b1_on	2.068	0	1	0	1	0
3x24	E1	class-b1_on	2.02698	0	1	0	2	1
4x68	5x38	class-b1_on	1.998	0	1	0	2	2
1x26	Lig	class-b1_on	1.70783	0	0	0	1	0
2x63	3x28	class-b1_on	1.66691	0	0	0	2	2
2x67	E1	class-b1_on	1.53442	0	0	0	2	1
1x36	2x62	class-b1_on	1.328	0	1	1	1	2
1x22	Lig	class-b1_on	1.09403	0	0	0	1	0
2x59	3x28	class-b1_on	0.992229	0	0	0	2	2
7x27	E3	class-b1_on	0.768325	0	0	0	2	1
1x23	Lig	class-b1_on	0.6064	0	0	0	1	0
6x55	E3	class-b1_on	0.559854	0	0	1	2	1
6x56	Lig	class-b1_on	0.481833	0	0	0	1	0
7x28	E3	class-b1_on	0.438	0	0	0	2	1
1x19	NT	class-b1_on	0.435	0	0	0	2	1
2x66	E1	Shared	0.168833	1.04667	0	0	2	1
3x21	E1	Shared	0.164333	1.75733	0	1	2	1
2x69	E1	class-b1_on	0.0748125	0	0	0	2	1
1x40	2x61	class-b2_on	0	3.851	0	0	2	2
3x29	E2	class-b2_on	0	5.68367	0	0	2	1
3x30	E2	class-b2_on	0	5.92233	0	0	2	1
3x32	E2x51	class-b2_on	0	5.30067	1	0	1	2
3x33	3x37	class-b2_on	0	5.69967	1	1	1	2
3x33	4x57	class-b2_on	0	4.34967	1	1	1	2
3x33	E2	class-b2_on	0	6.824	1	1	1	1
3x33	E2x52	class-b2_on	0	4.344	1	1	1	1
4x60	E2	class-b2_on	0	4.14867	1	0	2	1
4x61	E2	class-b2_on	0	3.82867	0	0	2	1
4x64	E2	class-b2_on	0	9.868	0	1	2	1
5x39	E2	class-b2_on	0	10.8387	0	1	2	1
E2	E2x52	class-b2_on	0	4.56233	1	1	1	1
5x40	E2x51	class-b2_on	0	4.326	0	1	2	2
5x43	E2x51	class-b2_on	0	5.189	1	0	2	2
5x39	E2x52	class-b2_on	0	4.915	0	1	2	1
5x40	E2x52	class-b2_on	0	4.17533	0	1	2	1
5x40	5x44	class-b2_on	0	3.464	0	1	2	1
6x48	7x37	class-b2_on	0	5.914	3	1	2	1
6x53	7x33	class-b2_on	0	6.44367	0	0	1	2
7x37	7x41	class-b2_on	0	14.3377	1	1	1	2
1x32	NT	class-b2_on	0	7.85567	0	0	1	1
1x36	NT	class-b2_on	0	4.64367	1	1	1	1
1x39	NT	class-b2_on	0	6.96233	1	0	1	1
2x57	NT	class-b2_on	0	8.84133	1	1	1	1
E2	NT	class-b2_on	0	14.6447	1	1	1	1
1x35	NT	class-b2_on	0	5.04567	0	1	2	1
1x43	NT	class-b2_on	0	3.80133	1	1	2	1
6x48	NT	class-b2_on	0	7.88333	3	1	2	1
7x37	NT	class-b2_on	0	8.49433	1	1	1	1
7x42	NT	class-b2_on	0	4.53833	1	1	2	1
7x34	NT	class-b2_on	0	8.28633	0	1	1	1
E2x51	NT	class-b2_on	0	9.036	1	1	2	1
3x36	NT	class-b2_on	0	8.117	1	1	1	1
5x44	NT	class-b2_on	0	5.328	1	1	1	1
5x40	NT	class-b2_on	0	3.34233	0	1	2	1
E3	NT	class-b2_on	0	8.60567	1	1	1	1
1x30	NT	class-b2_on	0	3.33067	0	0	2	1
E2x51	E2x52	class-b2_on	0	10.484	1	1	2	1
2x57	E1	class-b2_on	0	3.85267	1	1	1	1
1x29	E2	class-b2_on	0	4.248	1	0	1	1
7x30	7x33	class-b2_on	0	3.21267	0	0	1	2
3x33	5x42	class-b2_on	0	2.62667	1	1	1	2
7x38	NT	class-b2_on	0	2.579	1	1	1	1
E1	E2x50	class-b2_on	0	2.49933	1	1	1	2
7x33	E3	class-b2_on	0	2.46967	1	1	2	1
5x38	E2	class-b2_on	0	2.282	0	0	2	1
2x60	E2	class-b2_on	0	2.15967	1	1	1	1
6x54	7x34	class-b2_on	0	2.074	0	0	2	1
3x21	3x24	class-b2_on	0	2.041	0	1	2	2
1x38	7x38	class-b2_on	0	1.93333	0	0	2	1
6x55	NT	class-b2_on	0	1.852	0	1	2	1
2x59	2x60	class-b2_on	0	1.70933	0	0	2	1
6x57	7x30	class-b2_on	0	1.70533	0	0	2	1
1x28	NT	class-b2_on	0	1.572	0	0	1	1
5x51	6x52	class-b2_on	0	1.393	0	0	2	1
2x63	3x24	class-b2_on	0	1.298	0	0	2	2
3x33	5x421	class-b2_on	0	1.24267	1	1	1	2
4x65	E2	class-b2_on	0	0.928667	0	0	2	1
5x37	Lig	class-b2_on	0	0.723	0	0	1	0
6x55	6x56	class-b2_on	0	0.7	0	1	2	1
2x61	2x62	class-b2_on	0	0.494	1	0	2	2
6x58	NT	class-b2_on	0	0.460667	0	0	2	1
2x63	2x65	class-b2_on	0	0.428333	0	0	2	1

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Difference Members
	Id	Description
	class-b1_on	glucagon_on vip-pacap_on pth_on crf_on calcitonin_on
	class-b2_on	adgrg_on adgrf_on adgrl_on adgre_on adgrd_on

Network Difference
Value	class-b1_on	class-b2_on
I_min	3.73973	3.28
Number of Linked Nodes	276	262
Number of Specific Nodes	26 (9.42%)	12 (4.58%)
Number of Shared Nodes	250 (90.58%)	250 (95.42%)
Number of Links	304	284
Number of Specific Links	181 (59.54%)	161 (56.69%)
Number of Shared Links	123 (40.46%)	123 (43.31%)
Number of Hubs	36	30
Number of Specific Hubs	21 (58.33%)	15 (50.00%)
Number of Shared Hubs	15 (41.67%)	15 (50.00%)
Average % Shared Neighbours (Jaccard)	29.03
Average % Shared Neighbours (Otsuka)	37.31
Average % Shared Neighbours (Overlap Coefficient)	46.06
Average % Shared Cliques (k3-6)	75.00
Graphlets Similarity	0.610364

Paths Difference
Value	class-b1_on	class-b2_on
Number Of Nodes in MetaPath	51	69
Specific Nodes in MetaPath	24 (47.06%)	42 (60.87%)
Shared Nodes in MetaPath	250 (90.58%)	250 (90.58%)
Number Of Links MetaPath	51	71
Specific Links in MetaPath	39 (76.47%)	59 (83.10%)
Shared Links in MetaPath	123 (40.46%)	123 (40.46%)
Number of Shortest Paths	52776	37477
Length Of Smallest Path	3	3
Average Path Length	13.3667	12.3315
Length of Longest Path	30	33
Minimum Path Strength	0.671667	0.7815
Average Path Strength	6.51131	5.38159
Maximum Path Strength	35.1088	17.1435
Minimum Path Correlation	0.701133	0.700333
Average Path Correlation	0.940253	0.905687
Maximum Path Correlation	0.991	0.989
Minimum % Of Corr. Nodes	4.54545	3.22581
Average % Of Corr. Nodes	51.2194	45.8791
Maximum % Of Corr. Nodes	100	100
Minimum Path Hubs %	0	0
Average Path Hubs %	38.81	38.5354
Maximum Path Hubs %	100	100

Details about the values in these tables can be found in the corresponding documentation page .

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