psnGPCR

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Orange: nodes, hubs and links specific of d1_on_allo network

Green: nodes, hubs and links shared by both networks

Purple: nodes, hubs and links specific of d1_on network

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Owner: the name of the network the link belong to or "Shared" if the corresponding link is present in both networks.

Strength: the interaction strength between the two nodes or 0 if the link is not present.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Owner	d1_on_allo Int. Strength	d1_on Int. Strength	d1_on_allo Hub1?	d1_on Hub1?	d1_on_allo Hub2?	d1_on Hub2?	ConSurf1	ConSurf2
1	1x49	7x50	d1_on_allo	100	0	No	No	No	No	9	9
2	1x57	I1x50	d1_on_allo	100	0	No	Yes	Yes	No	8	9
3	1x59	8x57	d1_on_allo	100	0	No	No	No	No	6	6
4	2x38	I2x57	d1_on_allo	100	0	No	No	Yes	No	6	7
5	2x42	I2x57	d1_on_allo	100	0	Yes	Yes	Yes	No	8	7
6	2x53	7x42	d1_on_allo	100	0	No	No	Yes	Yes	8	7
7	2x56	3x28	d1_on_allo	100	0	No	No	Yes	No	8	5
8	3x27	3x31	d1_on_allo	100	0	No	No	No	No	6	5
9	3x28	3x32	d1_on_allo	100	0	Yes	No	Yes	No	5	7
10	3x29	E2.H164	d1_on_allo	100	0	No	No	Yes	No	5	5
11	3x45	4x45	d1_on_allo	100	0	No	No	No	No	7	7
12	3x49	I2x57	d1_on_allo	100	0	Yes	No	Yes	No	9	7
13	3x50	6x40	d1_on_allo	100	0	Yes	No	No	No	9	8
14	3x52	Alloh345	d1_on_allo	100	0	No	No	Yes	No	4	0
15	Alloh345	I2x52	d1_on_allo	100	0	Yes	No	Yes	No	0	5
16	Alloh345	I2x56	d1_on_allo	100	0	Yes	No	No	No	0	5
17	4x40	Alloh345	d1_on_allo	100	0	No	No	Yes	No	4	0
18	4x41	Alloh345	d1_on_allo	100	0	No	No	Yes	No	6	0
19	4x44	Alloh345	d1_on_allo	100	0	No	No	Yes	No	1	0
20	4x45	Alloh345	d1_on_allo	100	0	No	No	Yes	No	7	0
21	4x54	4x58	d1_on_allo	100	0	No	No	Yes	Yes	4	5
22	5x40	6x59	d1_on_allo	100	0	No	No	No	No	5	5
23	5x41	6x60	d1_on_allo	100	0	No	No	No	No	6	6
24	5x461	6x52	d1_on_allo	100	0	No	No	Yes	Yes	6	7
25	5x47	6x44	d1_on_allo	100	0	Yes	Yes	Yes	Yes	8	9
26	5x48	6x53	d1_on_allo	100	0	No	No	No	No	5	7
27	5x58	7x53	d1_on_allo	100	0	Yes	Yes	Yes	Yes	9	9
28	5x72	5x76	d1_on_allo	100	0	No	No	No	No	7	3
29	6x44	7x45	d1_on_allo	100	0	Yes	Yes	Yes	No	9	9
30	6x45	6x49	d1_on_allo	100	0	No	No	No	No	7	6
31	6x52	6x55	d1_on_allo	100	0	Yes	Yes	Yes	No	7	6
32	7x42	Lig	d1_on_allo	100	0	Yes	Yes	Yes	Yes	7	0
33	3x48	Alloh345	d1_on_allo	100	0	No	No	Yes	No	6	0
34	1x42	2x57	d1_on_allo	50	0	No	No	Yes	Yes	7	7
35	1x53	7x50	d1_on_allo	50	0	No	No	No	No	9	9
36	5x44	6x56	d1_on_allo	50	0	No	No	No	No	7	6
37	2x43	8x50	d1_on_allo	50	0	No	No	Yes	Yes	8	9
38	3x29	E2x52	d1_on_allo	0	0	No	No	No	No	5	5
39	2x41	I1x51	d1_on_allo	50	0	No	No	No	No	4	8
40	1x33	NT.F20	d1_on_allo	50	0	No	No	No	No	6	0
41	3x29	3x33	d1_on_allo	0	0	No	No	Yes	No	5	6
42	5x51	5x55	d1_on_allo	0	0	No	No	No	No	7	6
43	5x69	6x33	d1_on_allo	0	0	No	No	No	No	5	8
44	5x58	5x61	d1_on_allo	0	0	Yes	Yes	No	No	9	9
45	3x37	3x41	d1_on_allo	0	0	Yes	No	No	No	6	5
46	5x46	5x49	d1_on_allo	50	0	No	No	No	No	4	5
47	2x41	4x39	d1_on_allo	0	0	No	No	No	No	4	1
48	7x30	E3.I308	d1_on_allo	50	0	No	No	Yes	Yes	4	4
49	2x62	E1x51	d1_on_allo	0	0	No	No	Yes	No	4	1
50	1x43	2x58	d1_on_allo	0	0	No	No	No	No	6	8
51	1x43	2x61	d1_on_allo	0	0	No	No	No	No	6	6
52	5x45	5x46	d1_on_allo	0	0	No	No	No	No	4	4
53	7x37	7x40	d1_on_allo	50	0	No	No	No	No	5	7
54	8x52	I1x49	d1_on_allo	50	0	No	No	Yes	No	5	6
55	1x32	2x65	d1_on_allo	50	0	No	No	No	No	5	5
56	1x54	2x48	d1_on_allo	0	0	No	No	No	No	7	6
57	5x55	5x59	d1_on_allo	0	0	No	No	No	No	6	3
58	5x67	5x68	d1_on_allo	0	0	No	No	No	No	5	7
59	3x23	3x24	d1_on_allo	0	0	No	No	Yes	No	1	5
60	4x48	Alloh345	d1_on_allo	0	0	No	No	Yes	No	3	0
61	5x36	E2.A166	d1_on_allo	0	0	No	No	No	No	5	2
62	6x57	E3.C307	d1_on_allo	0	0	No	No	No	Yes	5	3
63	1x33	1x36	d1_on_allo	0	0	No	No	No	No	6	6
64	4x47	4x48	d1_on_allo	0	0	No	No	No	No	4	3
65	1x32	2x67	d1_on_allo	0	0	No	No	No	No	5	4
66	6x35	6x36	d1_on_allo	0	0	No	No	No	No	7	9
67	6x58	7x31	d1_on_allo	0	0	No	No	No	No	3	1
68	6x53	6x57	d1_on_allo	0	0	No	No	No	No	7	5
69	1x51	1x52	d1_on_allo	0	0	No	No	No	No	5	7
70	4x51	4x52	d1_on_allo	0	0	No	No	No	No	3	4
71	5x74	5x77	d1_on_allo	0	0	No	No	No	No	4	1
72	5x80	5x81	d1_on_allo	0	0	No	No	No	No	4	1
73	I2x51	I2x55	d1_on_allo	0	0	No	No	No	No	7	4
74	1x39	7x39	Shared	100	100	No	Yes	Yes	Yes	7	5
75	1x43	2x57	Shared	100	100	No	No	Yes	Yes	6	7
76	1x45	7x47	Shared	100	44.4444	No	No	No	No	4	6
77	1x46	1x50	Shared	100	100	Yes	Yes	Yes	Yes	7	9
78	1x46	2x57	Shared	100	100	Yes	Yes	Yes	Yes	7	7
79	1x46	7x47	Shared	100	100	Yes	Yes	No	No	7	6
80	1x48	1x52	Shared	100	55.5556	No	No	No	No	4	7
81	1x50	2x50	Shared	100	100	Yes	Yes	Yes	Yes	9	9
82	1x50	2x51	Shared	100	100	Yes	Yes	No	No	9	8
83	1x50	7x50	Shared	100	100	Yes	Yes	No	No	9	9
84	1x53	8x54	Shared	100	100	No	No	Yes	Yes	9	7
85	1x57	2x44	Shared	100	100	No	Yes	No	No	8	6
86	1x60	I1x49	Shared	100	100	Yes	Yes	Yes	No	6	6
87	1x60	8x53	Shared	100	100	Yes	Yes	No	No	6	7
88	1x60	8x56	Shared	100	100	Yes	Yes	No	No	6	4
89	I1x48	I1x51	Shared	100	100	No	No	No	No	7	8
90	I1x49	I1x50	Shared	100	100	Yes	No	Yes	No	6	9
91	8x49	I1x49	Shared	100	100	No	No	Yes	No	7	6
92	8x49	I1x50	Shared	100	100	No	No	Yes	No	7	9
93	8x50	I1x50	Shared	100	100	Yes	Yes	Yes	No	9	9
94	2x37	2x40	Shared	100	100	No	No	No	No	5	9
95	2x38	4x39	Shared	100	55.5556	No	No	No	No	6	1
96	2x39	3x49	Shared	100	100	No	No	Yes	No	8	9
97	2x39	I2x53	Shared	100	100	No	No	Yes	Yes	8	7
98	2x40	8x50	Shared	100	100	No	No	Yes	Yes	9	9
99	2x41	4x43	Shared	100	100	No	No	No	No	4	3
100	2x42	3x45	Shared	100	100	Yes	Yes	No	No	8	7
101	2x42	3x49	Shared	100	100	Yes	Yes	Yes	No	8	9
102	2x42	4x42	Shared	100	55.5556	Yes	Yes	No	No	8	7
103	2x42	4x45	Shared	100	100	Yes	Yes	No	No	8	7
104	2x42	4x46	Shared	100	100	Yes	Yes	No	No	8	8
105	2x45	3x42	Shared	100	100	No	No	No	No	9	8
106	2x45	4x46	Shared	100	100	No	No	No	No	9	8
107	2x45	4x50	Shared	100	100	No	No	Yes	Yes	9	9
108	2x46	2x50	Shared	100	100	Yes	Yes	Yes	Yes	9	9
109	2x46	3x42	Shared	100	100	Yes	Yes	No	No	9	8
110	2x46	3x43	Shared	100	100	Yes	Yes	Yes	Yes	9	9
111	2x46	7x49	Shared	100	100	Yes	Yes	Yes	Yes	9	9
112	2x49	4x50	Shared	100	100	No	No	Yes	Yes	8	9
113	2x50	3x39	Shared	100	100	Yes	Yes	No	No	9	9
114	2x50	7x46	Shared	100	100	Yes	Yes	No	No	9	9
115	2x50	7x49	Shared	100	100	Yes	Yes	Yes	Yes	9	9
116	2x53	3x35	Shared	100	100	No	No	No	No	8	7
117	2x53	7x46	Shared	100	100	No	No	No	No	8	9
118	2x55	2x551	Shared	100	44.4444	No	No	No	No	5	6
119	2x551	3x31	Shared	100	100	No	No	No	No	6	5
120	2x56	3x32	Shared	100	100	No	No	Yes	No	8	7
121	2x56	7x42	Shared	100	100	No	No	Yes	Yes	8	7
122	2x57	7x39	Shared	100	100	Yes	Yes	Yes	Yes	7	5
123	2x57	7x42	Shared	100	100	Yes	Yes	Yes	Yes	7	7
124	2x59	E1x52	Shared	100	100	No	Yes	Yes	Yes	5	6
125	2x59	3x24	Shared	100	100	No	Yes	Yes	No	5	5
126	2x59	3x28	Shared	100	100	No	Yes	Yes	No	5	5
127	2x60	3x28	Shared	100	100	Yes	Yes	Yes	No	6	5
128	2x60	7x35	Shared	100	100	Yes	Yes	No	No	6	4
129	2x60	7x39	Shared	100	100	Yes	Yes	Yes	Yes	6	5
130	2x60	7x42	Shared	100	100	Yes	Yes	Yes	Yes	6	7
131	2x64	7x35	Shared	100	100	No	No	No	No	4	4
132	E1x49	E1x51	Shared	100	44.4444	No	No	Yes	No	4	1
133	E1x50	E1x51	Shared	100	100	Yes	Yes	Yes	No	8	1
134	E1x50	E1x52	Shared	100	100	Yes	Yes	Yes	Yes	8	6
135	3x25	E1x50	Shared	100	100	No	No	Yes	Yes	9	8
136	3x28	E1x50	Shared	100	100	Yes	No	Yes	Yes	5	8
137	E1x50	E2x50	Shared	100	100	Yes	Yes	No	No	8	9
138	E1x51	E1x52	Shared	100	100	Yes	No	Yes	Yes	1	6
139	3x24	E1x52	Shared	100	100	Yes	No	Yes	Yes	5	6
140	3x24	3x27	Shared	100	100	Yes	No	No	No	5	6
141	3x25	E2x50	Shared	100	100	No	No	No	No	9	9
142	3x30	4x61	Shared	100	100	No	No	No	No	6	5
143	3x31	4x58	Shared	100	100	No	No	Yes	Yes	5	5
144	3x32	7x42	Shared	100	100	Yes	No	Yes	Yes	7	7
145	3x32	Lig	Shared	100	100	Yes	No	Yes	Yes	7	0
146	3x33	4x57	Shared	100	100	Yes	No	No	No	6	7
147	3x33	5x39	Shared	100	100	Yes	No	Yes	Yes	6	7
148	3x33	Lig	Shared	100	100	Yes	No	Yes	Yes	6	0
149	3x34	4x54	Shared	100	22.2222	No	No	No	No	5	4
150	3x34	4x57	Shared	100	100	No	No	No	No	5	7
151	3x34	4x58	Shared	100	100	No	No	Yes	Yes	5	5
152	3x36	6x48	Shared	100	100	No	No	Yes	Yes	7	8
153	3x36	Lig	Shared	100	100	No	No	Yes	Yes	7	0
154	3x37	4x53	Shared	100	100	Yes	No	No	No	6	8
155	3x37	4x56	Shared	100	66.6667	Yes	No	No	No	6	5
156	3x37	5x461	Shared	100	100	Yes	No	No	No	6	6
157	3x38	4x50	Shared	100	100	No	No	Yes	Yes	7	9
158	3x40	6x44	Shared	100	100	No	No	Yes	Yes	8	9
159	3x40	6x48	Shared	100	100	No	No	Yes	Yes	8	8
160	3x42	4x50	Shared	100	100	No	No	Yes	Yes	8	9
161	3x43	6x44	Shared	100	100	Yes	Yes	Yes	Yes	9	9
162	3x43	7x49	Shared	100	100	Yes	Yes	Yes	Yes	9	9
163	3x43	7x53	Shared	100	100	Yes	Yes	Yes	Yes	9	9
164	3x44	5x50	Shared	100	100	No	No	No	Yes	7	9
165	3x44	5x53	Shared	100	100	No	No	No	No	7	6
166	3x46	3x50	Shared	100	100	No	No	Yes	No	9	9
167	3x46	7x53	Shared	100	100	No	No	Yes	Yes	9	9
168	3x47	5x54	Shared	100	100	No	No	No	Yes	8	8
169	3x47	5x57	Shared	100	100	No	No	No	No	8	7
170	3x47	5x58	Shared	100	100	No	No	Yes	Yes	8	9
171	3x48	3x52	Shared	100	33.3333	No	No	No	No	6	4
172	3x49	I2x53	Shared	100	100	Yes	No	Yes	Yes	9	7
173	3x50	5x58	Shared	100	100	Yes	No	Yes	Yes	9	9
174	3x50	7x53	Shared	100	100	Yes	No	Yes	Yes	9	9
175	3x51	3x55	Shared	100	100	No	Yes	No	No	8	7
176	3x51	5x57	Shared	100	100	No	Yes	No	No	8	7
177	3x51	5x60	Shared	100	100	No	Yes	No	No	8	5
178	3x53	I2x53	Shared	100	100	No	No	Yes	Yes	8	7
179	3x54	5x61	Shared	100	100	No	No	No	No	8	9
180	3x54	5x64	Shared	100	100	No	No	No	No	8	6
181	I2x52	I2x56	Shared	100	44.4444	Yes	No	No	No	5	5
182	I2x53	I2x57	Shared	100	100	Yes	Yes	Yes	No	7	7
183	4x57	4x58	Shared	100	100	No	No	Yes	Yes	7	5
184	4x60	E2.W163	Shared	100	100	No	No	No	No	6	6
185	4x60	5x39	Shared	100	100	No	No	Yes	Yes	6	7
186	4x61	E2.H164	Shared	100	100	No	No	Yes	No	5	5
187	4x63	E2.W163	Shared	100	100	No	No	No	No	4	6
188	4x64	E2.K165	Shared	100	44.4444	No	No	No	No	5	3
189	E2.H164	E2.K165	Shared	100	100	Yes	No	No	No	5	3
190	E2.N185	E2x51	Shared	100	100	No	No	No	No	4	5
191	E2.L190	Lig	Shared	100	100	No	No	Yes	Yes	4	0
192	5x37	6x60	Shared	100	100	No	No	No	No	4	6
193	5x39	5x43	Shared	100	100	Yes	Yes	No	No	7	7
194	5x43	Lig	Shared	100	100	No	No	Yes	Yes	7	0
195	5x44	6x52	Shared	100	100	No	No	Yes	Yes	7	7
196	5x44	6x55	Shared	100	100	No	No	Yes	No	7	6
197	5x461	Lig	Shared	100	100	No	No	Yes	Yes	6	0
198	5x47	5x48	Shared	100	100	Yes	Yes	No	No	8	5
199	5x47	5x51	Shared	100	100	Yes	Yes	No	No	8	7
200	5x47	6x49	Shared	100	100	Yes	Yes	No	No	8	6
201	5x47	6x52	Shared	100	100	Yes	Yes	Yes	Yes	8	7
202	5x51	6x44	Shared	100	100	No	No	Yes	Yes	7	9
203	5x54	6x41	Shared	100	100	No	Yes	No	Yes	8	8
204	5x54	6x44	Shared	100	100	No	Yes	Yes	Yes	8	9
205	5x56	5x60	Shared	100	100	No	No	No	No	4	5
206	5x58	6x37	Shared	100	100	Yes	Yes	No	No	9	8
207	5x58	6x40	Shared	100	100	Yes	Yes	No	No	9	8
208	5x58	6x41	Shared	100	100	Yes	Yes	No	Yes	9	8
209	5x59	5x63	Shared	100	44.4444	No	No	No	No	3	4
210	5x62	5x66	Shared	100	100	Yes	Yes	No	No	7	6
211	5x62	6x34	Shared	100	100	Yes	Yes	No	No	7	7
212	5x66	6x30	Shared	100	100	No	No	No	Yes	6	8
213	5x68	5x71	Shared	100	11.1111	No	No	No	No	7	5
214	5x69	6x29	Shared	100	100	No	No	No	Yes	5	6
215	5x72	6x29	Shared	100	100	No	No	No	Yes	7	6
216	5x76	6x29	Shared	100	33.3333	No	No	No	Yes	3	6
217	6x27	6x30	Shared	100	22.2222	No	No	No	Yes	5	8
218	6x27	6x31	Shared	100	33.3333	No	No	No	No	5	5
219	6x39	7x52	Shared	100	0	No	No	No	No	7	8
220	6x43	7x52	Shared	100	44.4444	No	No	No	No	7	8
221	6x44	6x48	Shared	100	100	Yes	Yes	Yes	Yes	9	8
222	6x47	7x45	Shared	100	100	No	No	Yes	No	9	9
223	6x48	6x51	Shared	100	100	Yes	Yes	Yes	Yes	8	7
224	6x48	6x52	Shared	100	100	Yes	Yes	Yes	Yes	8	7
225	6x48	7x41	Shared	100	100	Yes	Yes	No	No	8	7
226	6x48	7x45	Shared	100	100	Yes	Yes	Yes	No	8	9
227	6x50	7x37	Shared	100	100	No	No	No	No	9	5
228	6x51	6x52	Shared	100	100	Yes	Yes	Yes	Yes	7	7
229	6x51	6x55	Shared	100	100	Yes	Yes	Yes	No	7	6
230	6x51	7x34	Shared	100	100	Yes	Yes	Yes	Yes	7	4
231	6x51	7x38	Shared	100	100	Yes	Yes	No	Yes	7	6
232	6x51	Lig	Shared	100	100	Yes	Yes	Yes	Yes	7	0
233	6x52	Lig	Shared	100	100	Yes	Yes	Yes	Yes	7	0
234	6x54	E3.I308	Shared	100	100	No	No	Yes	Yes	5	4
235	6x54	7x34	Shared	100	100	No	No	Yes	Yes	5	4
236	6x54	7x37	Shared	100	100	No	No	No	No	5	5
237	6x55	Lig	Shared	100	100	Yes	No	Yes	Yes	6	0
238	6x58	7x34	Shared	100	100	No	No	Yes	Yes	3	4
239	6x61	E3.C307	Shared	100	100	No	No	No	Yes	4	3
240	7x33	E3.I308	Shared	100	100	No	No	Yes	Yes	4	4
241	7x34	7x38	Shared	100	100	Yes	Yes	No	Yes	4	6
242	7x38	7x42	Shared	100	100	No	Yes	Yes	Yes	6	7
243	7x39	7x42	Shared	100	100	Yes	Yes	Yes	Yes	5	7
244	7x45	7x49	Shared	100	100	Yes	No	Yes	Yes	9	9
245	7x51	7x55	Shared	100	100	No	No	No	No	7	8
246	7x52	7x53	Shared	100	100	No	No	Yes	Yes	8	9
247	7x54	8x50	Shared	100	100	No	No	Yes	Yes	6	9
248	7x55	8x51	Shared	100	100	No	No	No	No	8	8
249	8x47	8x50	Shared	100	100	No	No	Yes	Yes	8	9
250	3x26	E2.H164	Shared	100	22.2222	No	No	Yes	No	6	5
251	5x64	5x67	Shared	100	22.2222	No	No	No	No	6	5
252	5x66	5x70	Shared	100	100	No	No	No	No	6	5
253	5x77	5x81	Shared	100	11.1111	No	No	No	No	1	1
254	7x30	7x32	Shared	100	22.2222	No	No	No	No	4	1
255	5x62	6x37	Shared	50	100	Yes	Yes	No	No	7	8
256	3x41	4x52	Shared	50	55.5556	No	No	No	No	5	4
257	1x53	2x47	Shared	0	55.5556	No	No	No	No	9	9
258	4x59	4x60	Shared	0	100	No	No	No	No	6	6
259	5x49	5x50	Shared	0	100	No	No	No	Yes	5	9
260	1x46	2x54	Shared	0	100	Yes	Yes	No	No	7	7
261	3x56	I2x52	Shared	50	100	No	No	Yes	No	6	5
262	6x58	6x59	Shared	50	44.4444	No	No	No	No	3	5
263	7x36	7x40	Shared	50	11.1111	No	No	No	No	4	7
264	5x41	6x56	Shared	0	33.3333	No	No	No	No	6	6
265	1x36	2x65	Shared	0	22.2222	No	No	No	No	6	5
266	8x50	8x54	Shared	50	100	Yes	Yes	Yes	Yes	9	7
267	1x59	1x60	Shared	50	33.3333	No	No	Yes	Yes	6	6
268	2x52	3x35	Shared	50	33.3333	No	No	No	No	7	7
269	3x41	4x49	Shared	50	33.3333	No	No	No	No	5	7
270	5x62	6x33	Shared	50	22.2222	Yes	Yes	No	No	7	8
271	1x47	2x54	Shared	0	11.1111	No	No	No	No	7	7
272	4x56	5x46	Shared	0	22.2222	No	No	No	No	5	4
273	3x22	E1x50	Shared	0	0	No	No	Yes	Yes	7	8
274	1x56	8x54	Shared	0	11.1111	No	No	Yes	Yes	8	7
275	I2x52	I2x55	Shared	50	100	Yes	No	No	No	5	4
276	4x38	4x39	Shared	50	100	No	No	No	No	8	1
277	2x63	E1x50	Shared	0	33.3333	No	No	Yes	Yes	5	8
278	5x36	5x39	Shared	50	33.3333	No	No	Yes	Yes	5	7
279	5x65	6x33	Shared	0	44.4444	No	No	No	No	9	8
280	1x42	7x43	Shared	0	22.2222	No	No	No	No	7	4
281	6x43	7x48	Shared	0	0	No	No	No	No	7	6
282	1x35	1x39	Shared	0	11.1111	No	No	No	Yes	5	7
283	7x55	8x54	Shared	50	22.2222	No	No	Yes	Yes	8	7
284	4x55	4x59	Shared	0	0	No	No	No	No	4	6
285	2x66	E1x49	Shared	50	22.2222	No	No	No	No	5	4
286	1x52	8x54	Shared	0	100	No	No	Yes	Yes	7	7
287	3x56	I2x50	Shared	0	0	No	No	No	No	6	8
288	6x41	6x42	Shared	0	11.1111	No	Yes	No	No	8	5
289	E2.A166	E2.S189	Shared	50	0	No	No	No	No	2	4
290	1x54	2x51	Shared	0	11.1111	No	No	No	No	7	8
291	8x58	CT.C347	Shared	0	11.1111	No	No	No	No	7	9
292	1x55	8x57	Shared	0	22.2222	No	No	No	No	5	6
293	1x57	1x58	Shared	0	0	No	Yes	No	No	8	4
294	1x40	1x44	Shared	0	22.2222	No	No	No	No	4	5
295	6x32	6x36	Shared	0	0	No	No	No	No	8	9
296	6x28	6x31	Shared	0	11.1111	No	No	No	No	5	5
297	3x27	4x62	Shared	0	33.3333	No	No	No	No	6	5
298	1x38	1x39	Shared	0	33.3333	No	No	No	Yes	3	7
299	I2x53	I2x54	Shared	0	0	Yes	Yes	No	No	7	5
300	2x66	2x67	Shared	0	0	No	No	No	No	5	4
301	6x46	6x47	Shared	0	0	No	No	No	No	5	9
302	8x58	8x59	Shared	0	0	No	No	No	No	7	5
303	E2.K167	E2.P168	Shared	0	22.2222	No	No	No	No	2	1
304	1x33	1x37	Shared	0	0	No	No	No	No	6	5
305	5x36	5x38	Shared	0	0	No	No	No	No	5	4
306	1x31	1x35	Shared	0	0	No	No	No	No	4	5
307	2x37	I1x52	Shared	0	11.1111	No	No	No	No	5	8
308	6x36	6x40	Shared	0	0	No	No	No	No	9	8
309	5x80	5x84	Shared	0	0	No	No	No	No	4	4
310	1x51	2x51	Shared	0	0	No	No	No	No	5	8
311	6x57	E3.I308	Shared	0	0	No	No	Yes	Yes	5	4
312	4x51	4x55	Shared	0	0	No	No	No	No	3	4
313	E2.S189	E2x51	Shared	0	11.1111	No	No	No	No	4	5
314	6x26	6x27	Shared	0	22.2222	No	No	No	No	0	5
315	1x39	2x61	d1_on	0	100	No	Yes	No	No	7	6
316	2x46	7x53	d1_on	0	100	Yes	Yes	Yes	Yes	9	9
317	3x30	4x58	d1_on	0	100	No	No	Yes	Yes	6	5
318	3x52	I2x53	d1_on	0	100	No	No	Yes	Yes	4	7
319	5x45	5x48	d1_on	0	100	No	No	No	No	4	5
320	5x48	6x56	d1_on	0	100	No	No	No	No	5	6
321	5x54	5x58	d1_on	0	100	No	Yes	Yes	Yes	8	9
322	5x62	6x30	d1_on	0	100	Yes	Yes	No	Yes	7	8
323	2x64	7x39	d1_on	0	100	No	No	Yes	Yes	4	5
324	3x29	Lig	d1_on	0	100	No	No	Yes	Yes	5	0
325	4x40	4x44	d1_on	0	100	No	No	No	No	4	1
326	E2x52	Lig	d1_on	0	100	No	No	Yes	Yes	5	0
327	5x37	6x59	d1_on	0	100	No	No	No	No	4	5
328	7x38	Lig	d1_on	0	100	No	Yes	Yes	Yes	6	0
329	7x30	7x33	d1_on	0	22.2222	No	No	No	No	4	4
330	5x60	5x63	d1_on	0	11.1111	No	No	No	No	5	4
331	3x51	5x61	d1_on	0	44.4444	No	Yes	No	No	8	9
332	5x55	6x41	d1_on	0	33.3333	No	No	No	Yes	6	8
333	3x55	3x56	d1_on	0	44.4444	No	No	No	No	7	6
334	6x49	6x53	d1_on	0	33.3333	No	No	No	No	6	7
335	3x40	5x50	d1_on	0	44.4444	No	No	No	Yes	8	9
336	2x38	2x41	d1_on	0	22.2222	No	No	No	No	6	4
337	5x69	6x30	d1_on	0	22.2222	No	No	No	Yes	5	8
338	1x60	8x57	d1_on	0	44.4444	Yes	Yes	No	No	6	6
339	3x41	5x50	d1_on	0	22.2222	No	No	No	Yes	5	9
340	6x41	6x45	d1_on	0	33.3333	No	Yes	No	No	8	7
341	2x62	E1x52	d1_on	0	33.3333	No	No	Yes	Yes	4	6
342	1x48	1x49	d1_on	0	11.1111	No	No	No	No	4	9
343	5x40	E2.L190	d1_on	0	11.1111	No	No	No	No	5	4
344	2x58	2x59	d1_on	0	33.3333	No	No	No	Yes	8	5
345	2x37	2x39	d1_on	0	22.2222	No	No	No	No	5	8
346	1x38	1x42	d1_on	0	22.2222	No	No	No	No	3	7
347	2x41	4x42	d1_on	0	22.2222	No	No	No	No	4	7
348	2x43	3x46	d1_on	0	11.1111	No	No	No	No	8	9
349	1x57	8x50	d1_on	0	0	No	Yes	Yes	Yes	8	9
350	1x57	I1x51	d1_on	0	22.2222	No	Yes	No	No	8	8
351	6x59	E2.S189	d1_on	0	22.2222	No	No	No	No	5	4
352	E3.C307	E3.I308	d1_on	0	22.2222	No	Yes	Yes	Yes	3	4
353	2x48	4x50	d1_on	0	0	No	No	Yes	Yes	6	9
354	8x52	8x55	d1_on	0	11.1111	No	No	No	No	5	5
355	4x38	4x40	d1_on	0	0	No	No	No	No	8	4
356	8x55	CT.Y348	d1_on	0	11.1111	No	No	No	No	5	0
357	4x44	4x48	d1_on	0	0	No	No	No	No	1	3
358	E3.C307	E3.T303	d1_on	0	11.1111	No	Yes	No	No	3	0
359	4x41	I2x57	d1_on	0	0	No	No	Yes	No	6	7
360	6x35	6x39	d1_on	0	11.1111	No	No	No	No	7	7
361	7x40	7x41	d1_on	0	0	No	No	No	No	7	7
362	8x52	8x56	d1_on	0	11.1111	No	No	No	No	5	4
363	7x31	7x32	d1_on	0	11.1111	No	No	No	No	1	1
364	5x73	5x77	d1_on	0	11.1111	No	No	No	No	4	1
365	5x64	5x68	d1_on	0	0	No	No	No	No	6	7
366	8x60	8x61	d1_on	0	11.1111	No	No	No	No	0	0
367	1x30	NT.F20	d1_on	0	11.1111	No	No	No	No	4	0
368	5x85	6x29	d1_on	0	11.1111	No	No	No	Yes	0	6
369	5x81	5x84	d1_on	0	11.1111	No	No	No	No	1	4
370	E3.P305	E3.T303	d1_on	0	11.1111	No	No	No	No	0	0
371	6x61	E3.F306	d1_on	0	11.1111	No	No	No	No	4	0
372	1x34	1x38	d1_on	0	11.1111	No	No	No	No	4	3
373	3x23	3x26	d1_on	0	11.1111	No	No	No	No	1	6
374	1x52	8x58	d1_on	0	0	No	No	No	No	7	7
375	1x32	NT.F20	d1_on	0	11.1111	No	No	No	No	5	0
376	5x77	6x26	d1_on	0	0	No	No	No	No	1	0
377	2x65	NT.F20	d1_on	0	11.1111	No	No	No	No	5	0
378	1x30	1x31	d1_on	0	11.1111	No	No	No	No	4	4
379	4x47	4x51	d1_on	0	0	No	No	No	No	4	3
380	8x47	8x48	d1_on	0	0	No	No	No	No	8	5
381	I2x51	I2x54	d1_on	0	0	No	No	No	No	7	5
382	1x33	1x34	d1_on	0	0	No	No	No	No	6	4
383	1x43	1x44	d1_on	0	0	No	No	No	No	6	5
384	E3.C307	E3.G299	d1_on	0	0	No	Yes	No	No	3	0
385	8x55	8x61	d1_on	0	0	No	No	No	No	5	0
386	5x39	5x42	d1_on	0	0	Yes	Yes	No	No	7	4
387	5x37	E2.K167	d1_on	0	0	No	No	No	No	4	2
388	E3.G299	E3.S300	d1_on	0	11.1111	No	No	No	No	0	0
389	E3.G301	E3.S300	d1_on	0	11.1111	No	No	No	No	0	0
390	3x22	E2.D184	d1_on	0	11.1111	No	No	No	No	7	0
391	1x37	1x41	d1_on	0	0	No	No	No	No	5	4
392	E3.P305	E3.Q304	d1_on	0	11.1111	No	No	No	No	0	0
393	5x70	5x74	d1_on	0	11.1111	No	No	No	No	5	4
394	5x83	5x86	d1_on	0	0	No	No	No	No	3	0
395	6x62	E3.C307	d1_on	0	0	No	No	No	Yes	0	3
396	6x38	6x39	d1_on	0	0	No	No	No	No	6	7
397	5x74	5x75	d1_on	0	0	No	No	No	No	4	4
398	5x80	5x83	d1_on	0	0	No	No	No	No	4	3
399	5x78	5x81	d1_on	0	0	No	No	No	No	4	1
400	1x29	1x31	d1_on	0	0	No	No	No	No	0	4

Orange: nodes, hubs and links specific of d1_on_allo network

Green: nodes, hubs and links shared by both networks

Purple: nodes, hubs and links specific of d1_on network

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Owner: the name of the network the hub belong to or "Shared" if the corresponding hub is present in both networks.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub in the corresponding network.

Num Of Links: the number of links of the corresponding hub in the corresponding network.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Owner	d1_on_allo Avg Int. Strength	d1_on Avg Int. Strength	d1_on_allo Num Of Links	d1_on Num Of Links	ConSurf
1	I1x49	d1_on_allo	50	0	4	3	6
2	I1x50	d1_on_allo	50	0	4	3	9
3	E1x51	d1_on_allo	0	11.1111	4	3	1
4	3x24	d1_on_allo	0	22.2222	4	3	5
5	3x28	d1_on_allo	100	66.6667	5	3	5
6	3x32	d1_on_allo	100	77.7778	4	3	7
7	3x33	d1_on_allo	0	22.2222	4	3	6
8	3x37	d1_on_allo	0	22.2222	4	3	6
9	3x49	d1_on_allo	50	33.3333	4	3	9
10	3x50	d1_on_allo	50	11.1111	4	3	9
11	I2x52	d1_on_allo	50	0	4	3	5
12	I2x57	d1_on_allo	50	22.2222	4	2	7
13	E2.H164	d1_on_allo	50	22.2222	4	3	5
14	6x55	d1_on_allo	50	22.2222	4	3	6
15	7x45	d1_on_allo	100	44.4444	4	3	9
16	Alloh345	d1_on_allo	100	0	9	0	0
17	1x46	Shared	0	66.6667	4	4	7
18	1x50	Shared	50	55.5556	4	4	9
19	1x60	Shared	100	55.5556	4	5	6
20	2x42	Shared	100	100	6	5	8
21	2x46	Shared	100	55.5556	4	5	9
22	2x50	Shared	100	88.8889	5	5	9
23	2x57	Shared	100	66.6667	5	4	7
24	2x60	Shared	100	55.5556	4	4	6
25	E1x50	Shared	50	77.7778	7	7	8
26	E1x52	Shared	50	33.3333	4	5	6
27	3x43	Shared	100	66.6667	4	4	9
28	I2x53	Shared	100	100	5	6	7
29	4x50	Shared	50	33.3333	4	5	9
30	4x58	Shared	50	22.2222	4	4	5
31	5x39	Shared	100	77.7778	4	5	7
32	5x47	Shared	100	88.8889	5	4	8
33	5x58	Shared	100	66.6667	7	6	9
34	5x62	Shared	0	33.3333	4	5	7
35	6x44	Shared	100	77.7778	7	5	9
36	6x48	Shared	100	100	7	7	8
37	6x51	Shared	100	100	6	6	7
38	6x52	Shared	100	100	7	5	7
39	E3.I308	Shared	0	0	4	4	4
40	7x34	Shared	50	55.5556	4	4	4
41	7x39	Shared	100	77.7778	4	5	5
42	7x42	Shared	100	100	8	6	7
43	7x49	Shared	100	44.4444	4	4	9
44	7x53	Shared	100	100	5	5	9
45	8x50	Shared	100	77.7778	6	6	9
46	8x54	Shared	0	11.1111	5	5	7
47	Lig	Shared	100	100	10	12	0
48	1x39	d1_on	0	11.1111	3	4	7
49	1x57	d1_on	0	0	3	4	8
50	2x59	d1_on	0	33.3333	3	4	5
51	3x51	d1_on	0	55.5556	3	4	8
52	5x50	d1_on	0	0	2	4	9
53	5x54	d1_on	0	44.4444	3	4	8
54	6x29	d1_on	0	0	3	4	6
55	6x30	d1_on	0	0	2	4	8
56	6x41	d1_on	50	22.2222	3	5	8
57	E3.C307	d1_on	0	0	2	5	3
58	7x38	d1_on	0	0	3	4	6

Orange: nodes, hubs and links specific of d1_on_allo network

Green: nodes, hubs and links shared by both networks

Purple: nodes, hubs and links specific of d1_on network

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Owner: the name of the network the link belong to or "Shared" if the corresponding link is present in both networks.

Recurrence: the relative Recurrence in the filtered pool of shortest paths.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Owner	d1_on_allo Recurrence	d1_on Recurrence	d1_on_allo Hub1?	d1_on Hub1?	d1_on_allo Hub2?	d1_on Hub2?	ConSurf1	ConSurf2
1	1x50	7x50	d1_on_allo	33.5993	1.19542	Yes	Yes	No	No	9	9
2	2x53	7x42	d1_on_allo	19.3114	0	No	No	Yes	Yes	8	7
3	2x53	7x46	d1_on_allo	18.9308	3.92594	No	No	No	No	8	9
4	2x50	7x46	d1_on_allo	19.0815	5.22508	Yes	Yes	No	No	9	9
5	1x53	7x50	d1_on_allo	31.4166	0	No	No	No	No	9	9
6	1x53	8x54	d1_on_allo	29.2234	3.30619	No	No	Yes	Yes	9	7
7	2x42	I2x57	d1_on_allo	20.2838	0	Yes	Yes	Yes	No	8	7
8	2x38	I2x57	d1_on_allo	13.1306	0	No	No	Yes	No	6	7
9	2x38	4x39	d1_on_allo	11.2702	8.23047	No	No	No	No	6	1
10	2x42	4x45	d1_on_allo	27.7145	1.65439	Yes	Yes	No	No	8	7
11	2x50	7x49	d1_on_allo	15.3423	5.65035	Yes	Yes	Yes	Yes	9	9
12	3x43	7x49	d1_on_allo	11.0932	2.09003	Yes	Yes	Yes	Yes	9	9
13	7x42	Lig	d1_on_allo	29.6065	0	Yes	Yes	Yes	Yes	7	0
14	5x47	6x52	d1_on_allo	39.2252	5.48439	Yes	Yes	Yes	Yes	8	7
15	5x47	6x44	d1_on_allo	42.5442	0	Yes	Yes	Yes	Yes	8	9
16	2x59	3x28	d1_on_allo	14.6077	8.68686	No	Yes	Yes	No	5	5
17	3x31	4x58	d1_on_allo	10.2608	7.06099	No	No	Yes	Yes	5	5
18	E1x50	E1x51	d1_on_allo	26.7474	5.00726	Yes	Yes	Yes	No	8	1
19	E1x49	E1x51	d1_on_allo	22.1785	3.81703	No	No	Yes	No	4	1
20	3x29	3x33	d1_on_allo	19.3801	0	No	No	Yes	No	5	6
21	3x29	E2.H164	d1_on_allo	14.6606	0	No	No	Yes	No	5	5
22	3x37	5x461	d1_on_allo	18.6428	9.2703	Yes	No	No	No	6	6
23	3x43	7x53	d1_on_allo	63.161	6.29603	Yes	Yes	Yes	Yes	9	9
24	5x58	7x53	d1_on_allo	46.1248	0	Yes	Yes	Yes	Yes	9	9
25	3x47	5x58	d1_on_allo	32.6243	6.40234	No	No	Yes	Yes	8	9
26	5x54	6x41	d1_on_allo	33.2188	3.93891	No	Yes	No	Yes	8	8
27	5x58	6x41	d1_on_allo	30.6715	1.5014	Yes	Yes	No	Yes	9	8
28	4x45	Alloh345	d1_on_allo	25.9202	0	No	No	Yes	No	7	0
29	5x58	6x40	d1_on_allo	15.7361	3.21025	Yes	Yes	No	No	9	8
30	5x58	5x61	d1_on_allo	23.6213	0	Yes	Yes	No	No	9	9
31	3x54	5x61	d1_on_allo	19.6972	6.59683	No	No	No	No	8	9
32	3x54	5x64	d1_on_allo	15.7678	5.28731	No	No	No	No	8	6
33	5x36	5x39	d1_on_allo	29.2339	9.28586	No	No	Yes	Yes	5	7
34	5x36	E2.A166	d1_on_allo	19.5096	0	No	No	No	No	5	2
35	E2.A166	E2.S189	d1_on_allo	14.6394	1.11503	No	No	No	No	2	4
36	5x62	5x66	d1_on_allo	26.6575	4.08412	Yes	Yes	No	No	7	6
37	5x66	6x30	d1_on_allo	18.8119	0.168551	No	No	No	Yes	6	8
38	5x64	5x67	d1_on_allo	11.8331	1.32766	No	No	No	No	6	5
39	5x62	6x33	d1_on_allo	23.032	2.1393	Yes	Yes	No	No	7	8
40	5x69	6x33	d1_on_allo	15.1785	0	No	No	No	No	5	8
41	5x69	6x29	d1_on_allo	11.6825	4.00892	No	No	No	Yes	5	6
42	1x32	2x65	d1_on_allo	12.3907	0	No	No	No	No	5	5
43	1x32	2x67	d1_on_allo	14.7161	0	No	No	No	No	5	4
44	2x66	2x67	d1_on_allo	17.2106	1.2758	No	No	No	No	5	4
45	2x66	E1x49	d1_on_allo	19.6972	2.54901	No	No	No	No	5	4
46	6x36	6x40	d1_on_allo	16.6609	2.14449	No	No	No	No	9	8
47	3x28	3x32	d1_on_allo	40.2822	0	Yes	No	Yes	No	5	7
48	5x461	6x52	d1_on_allo	14.6632	0	No	No	Yes	Yes	6	7
49	1x39	7x39	Shared	10.0362	15.9242	No	Yes	Yes	Yes	7	5
50	1x46	2x57	Shared	26.2717	21.8572	Yes	Yes	Yes	Yes	7	7
51	1x46	1x50	Shared	26.2215	21.6731	Yes	Yes	Yes	Yes	7	9
52	1x50	2x50	Shared	27.4582	22.2435	Yes	Yes	Yes	Yes	9	9
53	8x50	8x54	Shared	23.9384	20.9522	Yes	Yes	Yes	Yes	9	7
54	8x50	I1x50	Shared	15.7995	22.1943	Yes	Yes	Yes	No	9	9
55	2x46	2x50	Shared	30.6001	21.8494	Yes	Yes	Yes	Yes	9	9
56	2x46	3x42	Shared	71.3395	100	Yes	Yes	No	No	9	8
57	2x45	3x42	Shared	64.395	92.9209	No	No	No	No	9	8
58	2x45	4x46	Shared	62.9681	92.2389	No	No	No	No	9	8
59	2x42	4x46	Shared	61.2504	90.8982	Yes	Yes	No	No	8	8
60	2x46	3x43	Shared	44.4494	42.3711	Yes	Yes	Yes	Yes	9	9
61	7x38	7x42	Shared	10.0732	24.235	No	Yes	Yes	Yes	6	7
62	6x48	6x51	Shared	45.5751	57.6989	Yes	Yes	Yes	Yes	8	7
63	6x44	6x48	Shared	100	74.191	Yes	Yes	Yes	Yes	9	8
64	3x43	6x44	Shared	77.3564	50.6872	Yes	Yes	Yes	Yes	9	9
65	6x51	Lig	Shared	37.6794	32.7741	Yes	Yes	Yes	Yes	7	0
66	3x36	Lig	Shared	33.787	29.429	No	No	Yes	Yes	7	0
67	3x36	6x48	Shared	34.0248	29.5872	No	No	Yes	Yes	7	8
68	6x52	Lig	Shared	65.3859	32.8856	Yes	Yes	Yes	Yes	7	0
69	6x48	6x52	Shared	45.266	30.6607	Yes	Yes	Yes	Yes	8	7
70	2x60	3x28	Shared	10.7312	24.4425	Yes	Yes	Yes	No	6	5
71	3x33	Lig	Shared	71.0858	59.317	Yes	No	Yes	Yes	6	0
72	3x33	4x57	Shared	22.0992	32.5615	Yes	No	No	No	6	7
73	4x57	4x58	Shared	14.8773	25.612	No	No	Yes	Yes	7	5
74	3x28	E1x50	Shared	41.3234	14.7495	Yes	No	Yes	Yes	5	8
75	5x43	Lig	Shared	31.1365	27.5127	No	No	Yes	Yes	7	0
76	5x39	5x43	Shared	28.7662	25.2515	Yes	Yes	No	No	7	7
77	5x54	6x44	Shared	74.9597	43.0324	No	Yes	Yes	Yes	8	9
78	3x47	5x54	Shared	40.2664	17.9805	No	No	No	Yes	8	8
79	3x47	5x57	Shared	10.9769	23.1485	No	No	No	No	8	7
80	3x33	5x39	Shared	29.2419	25.6483	Yes	No	Yes	Yes	6	7
81	4x60	5x39	Shared	24.2845	32.4162	No	No	Yes	Yes	6	7
82	5x58	6x37	Shared	61.1183	26.3043	Yes	Yes	No	No	9	8
83	5x62	6x37	Shared	57.247	25.363	Yes	Yes	No	No	7	8
84	6x27	6x30	Shared	15.3238	12.0553	No	No	No	Yes	5	8
85	6x48	7x45	Shared	23.2883	39.7314	Yes	Yes	Yes	No	8	9
86	6x54	7x34	Shared	12.5809	19.3497	No	No	Yes	Yes	5	4
87	2x57	7x42	Shared	22.6488	12.7528	Yes	Yes	Yes	Yes	7	7
88	2x60	7x42	Shared	13.297	19.889	Yes	Yes	Yes	Yes	6	7
89	7x45	7x49	Shared	24.4907	38.1911	Yes	No	Yes	Yes	9	9
90	6x51	7x34	Shared	12.3061	22.1009	Yes	Yes	Yes	Yes	7	4
91	2x46	7x49	Shared	19.174	34.0706	Yes	Yes	Yes	Yes	9	9
92	3x32	Lig	Shared	35.6341	11.2048	Yes	No	Yes	Yes	7	0
93	2x57	7x39	d1_on	5.54132	10.8313	Yes	Yes	Yes	Yes	7	5
94	2x42	3x49	d1_on	9.28573	74.4062	Yes	Yes	Yes	No	8	9
95	2x39	3x49	d1_on	1.87882	60.7172	No	No	Yes	No	8	9
96	2x37	2x39	d1_on	0	60.0819	No	No	No	No	5	8
97	2x37	2x40	d1_on	2.48659	57.1569	No	No	No	No	5	9
98	2x40	8x50	d1_on	3.72328	55.6867	No	No	Yes	Yes	9	9
99	I1x49	I1x50	d1_on	9.8063	18.9788	Yes	No	Yes	No	6	9
100	1x60	I1x49	d1_on	7.40163	17.41	Yes	Yes	Yes	No	6	6
101	3x49	I2x53	d1_on	5.57831	12.2783	Yes	No	Yes	Yes	9	7
102	2x42	4x42	d1_on	1.89467	14.7236	Yes	Yes	No	No	8	7
103	2x41	4x42	d1_on	0	13.1081	No	No	No	No	4	7
104	7x39	7x42	d1_on	9.96486	11.5885	Yes	Yes	Yes	Yes	5	7
105	6x51	7x38	d1_on	4.12758	11.936	Yes	Yes	No	Yes	7	6
106	2x46	7x53	d1_on	0	16.282	Yes	Yes	Yes	Yes	9	9
107	7x38	Lig	d1_on	0	12.382	No	Yes	Yes	Yes	6	0
108	3x30	4x58	d1_on	0	16.4065	No	No	Yes	Yes	6	5
109	3x30	4x61	d1_on	2.48923	14.0779	No	No	No	No	6	5
110	5x461	Lig	d1_on	5.29556	11.5444	No	No	Yes	Yes	6	0
111	3x50	7x53	d1_on	8.05433	14.3476	Yes	No	Yes	Yes	9	9
112	5x54	5x58	d1_on	0	20.7162	No	Yes	Yes	Yes	8	9
113	3x51	5x57	d1_on	8.79159	21.9064	No	Yes	No	No	8	7
114	4x59	4x60	d1_on	9.75346	18.5536	No	No	No	No	6	6
115	4x61	E2.H164	d1_on	4.97582	11.7441	No	No	Yes	No	5	5
116	6x58	7x34	d1_on	4.97582	10.6809	No	No	Yes	Yes	3	4
117	5x62	6x30	d1_on	0	17.4359	Yes	Yes	No	Yes	7	8
118	6x54	E3.I308	d1_on	6.60888	16.2613	No	No	Yes	Yes	5	4
119	4x55	4x59	d1_on	4.97054	13.9223	No	No	No	No	4	6
120	3x50	5x58	d1_on	0.171762	14.3657	Yes	No	Yes	Yes	9	9

Here, those paths that begin and end at given residue pair(s) or that pass through a residue are used to generate a novel metapath. Such a path filtering is particularly recommended if some information on allosteric residues is available. The selection syntax for a residue pair ("Pairs") is C:C:c534,A:A:?600 (the lower-case "c" stands for cytosine and "?" indicates any non standard amino acid or nucleotide residue). Selection of more than one apical residue pair has the following syntax: C:C:c534,A:A:?600,C:C:c534,A:A:E41. Only one residue can be selected as a tail ("Tail"). For midway residue(s), each residue must be separated by a comma as well e.g. A:A:?600,A:A:E41.

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Node1	Node2	Owner	Net1LinkStrength	Net2LinkStrength	Comm1	Comm2	Node1Shell	Node2Shell
2x56	3x32	Shared	7.13889	4.38	1	1	2	1
2x56	7x42	Shared	5.58444	4.9	1	1	2	1
2x57	7x39	Shared	4.52444	6.395	1	1	2	2
2x57	7x42	Shared	5.3	6.98	1	1	2	1
2x60	3x28	Shared	6.70222	11.6	1	1	2	2
2x60	7x39	Shared	5.41333	5.8	1	1	2	2
2x60	7x42	Shared	5.8	6.38	1	1	2	1
3x32	7x42	Shared	11.1656	12.84	1	1	1	1
3x32	Lig	Shared	12.83	15.09	1	1	1	0
3x33	4x57	Shared	4.30222	4.645	0	0	1	2
3x33	5x39	Shared	4.96889	5.44	0	0	1	2
3x33	Lig	Shared	10.8267	7.78	0	0	1	0
3x36	6x48	Shared	4.25556	6.175	0	0	1	2
3x36	Lig	Shared	6.91889	11.485	0	0	1	0
3x37	5x461	Shared	6.75222	7.995	0	0	2	1
E2.L190	Lig	Shared	10.0022	8.88	0	0	1	0
5x39	5x43	Shared	10.4567	12.08	0	0	2	1
5x43	Lig	Shared	7.82444	7.985	0	0	1	0
5x44	6x52	Shared	5.86889	6.605	0	1	2	1
5x44	6x55	Shared	4.13889	3.725	0	1	2	1
5x461	Lig	Shared	4.45778	6.995	0	1	1	0
5x47	6x52	Shared	24.1722	26.26	0	1	2	1
6x48	6x51	Shared	3.67556	4.51	1	1	2	1
6x48	6x52	Shared	6.34889	7.52	1	1	2	1
6x51	6x52	Shared	9.40778	12.86	1	1	1	1
6x51	6x55	Shared	5.77222	7.25	1	1	1	1
6x51	7x34	Shared	5.00222	5.36	1	1	1	2
6x51	7x38	Shared	4.36667	4.585	1	1	1	1
6x51	Lig	Shared	13.4622	19.165	1	1	1	0
6x52	Lig	Shared	8.12556	11.89	1	1	1	0
6x55	Lig	Shared	7.29333	9.78	1	1	1	0
7x34	7x38	Shared	3.78556	5.9	1	1	2	1
7x38	7x42	Shared	7.90222	7.97	1	1	1	1
7x39	7x42	Shared	11.3511	12.185	1	1	2	1
3x29	Lig	d1_on	3.47556	0	0	0	1	0
E2x52	Lig	d1_on	3.40889	0	0	0	1	0
7x38	Lig	d1_on	3.48222	0	1	1	1	0
5x40	E2.L190	d1_on	2.27889	0	0	0	2	1
2x53	7x42	d1_on_allo	0	3.68	0	0	2	1
2x56	3x28	d1_on_allo	0	3.68	1	1	2	2
3x28	3x32	d1_on_allo	0	8.375	0	1	2	1
3x29	E2.H164	d1_on_allo	0	4.15	0	0	1	2
5x461	6x52	d1_on_allo	0	3.96	0	1	1	1
6x52	6x55	d1_on_allo	0	3.625	1	1	1	1
7x42	Lig	d1_on_allo	0	4.805	1	1	1	0
3x29	E2x52	d1_on_allo	0	3.23	0	0	1	1
3x29	3x33	d1_on_allo	0	3.07	0	0	1	1

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Difference Members
	Id	Description
	d1_on_allo	7LJC-D₁-PubChem 86764103-Mevidalen-Gs/&β;1/&γ;2 7CKZ-D₁-Dopamine-Mevidalen-Gs/&β;1/&γ;2
	d1_on	7F0T-D₁-Dopamine-Gs/&β;1/&γ;2 7CKY-D₁-PW0464-Gs/&β;1/&γ;2 8IRR-D₁-Rotigotine-Gs/&β;1/&γ;2 7JV5-D₁-SKF81297-Gs/&β;1/&γ;2 7JVP-D₁-SKF83959-Gs/&β;1/&γ;2 7X2D-D₁-Tavapadon-Gs/&β;1/&γ;2 7JOZ-D₁-VFP-Gs/&β;1/&γ;2 7CKX-D₁-A77636-Gs/&β;1/&γ;2 7JVQ-D₁-Apomorphine-Gs/&β;1/&γ;2

Network Difference
Value	d1_on_allo	d1_on
I_min	3.58	3.32
Number of Linked Nodes	270	295
Number of Specific Nodes	1 (0.37%)	26 (8.81%)
Number of Shared Nodes	269 (99.63%)	269 (91.19%)
Number of Links	314	327
Number of Specific Links	73 (23.25%)	86 (26.30%)
Number of Shared Links	241 (76.75%)	241 (73.70%)
Number of Hubs	47	42
Number of Specific Hubs	16 (34.04%)	11 (26.19%)
Number of Shared Hubs	31 (65.96%)	31 (73.81%)
Average % Shared Neighbours (Jaccard)	60.31
Average % Shared Neighbours (Otsuka)	68.36
Average % Shared Neighbours (Overlap Coefficient)	77.26
Average % Shared Cliques (k3-6)	61.25
Graphlets Similarity	0.697938

Paths Difference
Value	d1_on_allo	d1_on
Number Of Nodes in MetaPath	82	65
Specific Nodes in MetaPath	34 (41.46%)	17 (26.15%)
Shared Nodes in MetaPath	269 (99.63%)	269 (99.63%)
Number Of Links MetaPath	92	72
Specific Links in MetaPath	48 (52.17%)	28 (38.89%)
Shared Links in MetaPath	241 (76.75%)	241 (76.75%)
Number of Shortest Paths	107379	85955
Length Of Smallest Path	3	3
Average Path Length	13.0315	14.2146
Length of Longest Path	27	31
Minimum Path Strength	0.715	0.241667
Average Path Strength	6.76295	5.65018
Maximum Path Strength	25.91	16.79
Minimum Path Correlation	0.705	0.704444
Average Path Correlation	0.928672	0.933164
Maximum Path Correlation	0.99	0.991111
Minimum % Of Corr. Nodes	4.34783	3.7037
Average % Of Corr. Nodes	47.0803	48.7713
Maximum % Of Corr. Nodes	100	100
Minimum Path Hubs %	0	0
Average Path Hubs %	54.4647	47.2386
Maximum Path Hubs %	100	100

Details about the values in these tables can be found in the corresponding documentation page .

You can download a compressed (zip) file with structure(s), 3D outputs (as PyMol and VMD scripts) and numerical data files (as csv and plain text files).

Download d1_on_ortoallo.zip<

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