psnGPCR

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Orange: nodes, hubs and links specific of d3_off network

Green: nodes, hubs and links shared by both networks

Purple: nodes, hubs and links specific of d3_on network

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Owner: the name of the network the link belong to or "Shared" if the corresponding link is present in both networks.

Strength: the interaction strength between the two nodes or 0 if the link is not present.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Owner	d3_off Int. Strength	d3_on Int. Strength	d3_off Hub1?	d3_on Hub1?	d3_off Hub2?	d3_on Hub2?	ConSurf1	ConSurf2
1	1x35	1x39	d3_off	3.97	0	Yes	Yes	Yes	Yes	5	7
2	1x35	2x64	d3_off	6.73	0	Yes	Yes	No	No	5	6
3	1x42	2x57	d3_off	4.24	0	No	No	Yes	No	7	8
4	1x46	7x46	d3_off	6.19	0	Yes	Yes	No	No	8	9
5	1x49	7x50	d3_off	4.06	0	No	No	No	No	9	9
6	1x53	2x47	d3_off	3.39	0	Yes	No	No	No	9	9
7	1x53	7x50	d3_off	3.53	0	Yes	No	No	No	9	9
8	1x53	7x53	d3_off	3.79	0	Yes	No	Yes	Yes	9	9
9	1x53	8x54	d3_off	3.93	0	Yes	No	Yes	Yes	9	9
10	8x49	I1x49	d3_off	6.03	0	No	No	No	No	7	6
11	8x49	I1x50	d3_off	7.95	0	No	No	Yes	No	7	9
12	2x38	3x49	d3_off	4.34	0	No	No	Yes	No	6	9
13	2x39	3x49	d3_off	7.23	0	No	No	Yes	No	8	9
14	2x39	3x50	d3_off	9.06	0	No	No	Yes	No	8	9
15	2x43	7x53	d3_off	11.36	0	No	No	Yes	Yes	8	9
16	2x46	3x42	d3_off	6.87	0	No	No	No	No	9	9
17	2x56	7x42	d3_off	3.79	0	No	No	Yes	Yes	8	8
18	2x62	2x63	d3_off	3.52	0	Yes	No	No	No	6	5
19	2x62	E1x50	d3_off	3.86	0	Yes	No	Yes	Yes	6	9
20	2x62	E1x51	d3_off	5.81	0	Yes	No	No	No	6	4
21	E1x49	E2.T179	d3_off	4.76	0	No	No	No	No	3	2
22	3x22	E2.N173	d3_off	3.62	0	No	No	No	No	3	5
23	3x28	3x29	d3_off	5.24	0	No	No	No	No	7	7
24	3x30	4x61	d3_off	7.37	0	No	No	No	No	7	7
25	3x35	4x50	d3_off	4.65	0	Yes	No	No	No	5	9
26	3x37	4x56	d3_off	6.35	0	No	No	No	No	8	7
27	3x39	6x44	d3_off	3.96	0	No	No	Yes	Yes	9	9
28	3x40	3x41	d3_off	4.7	0	No	No	Yes	No	9	7
29	3x40	5x50	d3_off	8.47	0	No	No	No	No	9	9
30	3x40	6x44	d3_off	7.54	0	No	No	Yes	Yes	9	9
31	3x41	3x44	d3_off	3.92	0	Yes	No	Yes	No	7	7
32	3x41	5x49	d3_off	4.56	0	Yes	No	No	No	7	7
33	3x41	5x50	d3_off	27.02	0	Yes	No	No	No	7	9
34	3x43	6x44	d3_off	4.87	0	No	No	Yes	Yes	8	9
35	3x46	6x37	d3_off	4.61	0	No	No	No	No	9	8
36	3x49	3x50	d3_off	8.34	0	Yes	No	Yes	No	9	9
37	3x50	3x53	d3_off	5.53	0	Yes	No	No	No	9	8
38	3x50	I2x53	d3_off	9.26	0	Yes	No	Yes	Yes	9	8
39	3x50	6x30	d3_off	8.14	0	Yes	No	No	Yes	9	8
40	3x50	6x33	d3_off	4.15	0	Yes	No	No	No	9	8
41	3x50	6x34	d3_off	9.06	0	Yes	No	No	No	9	8
42	3x54	5x65	d3_off	4.47	0	No	No	No	No	8	8
43	6x26	I2x50	d3_off	3.53	0	No	No	No	No	5	8
44	I2x53	I2x57	d3_off	9.99	0	Yes	Yes	No	No	8	6
45	6x30	I2x53	d3_off	5.61	0	No	Yes	Yes	Yes	8	8
46	6x27	I2x54	d3_off	6.32	0	No	No	No	No	5	6
47	I2.Q144	I2x56	d3_off	4.93	0	No	No	No	No	5	4
48	4x56	5x42	d3_off	3.79	0	No	No	No	No	7	6
49	4x60	E2.F172	d3_off	4.33	0	No	No	No	No	7	6
50	4x60	5x39	d3_off	5.78	0	No	No	Yes	No	7	7
51	4x62	4x63	d3_off	3.65	0	No	No	No	No	7	5
52	E2.S184	E2.T175	d3_off	4.8	0	No	No	No	No	5	4
53	E2x52	Lig	d3_off	16.12	0	No	No	Yes	Yes	7	0
54	5x36	5x39	d3_off	3.62	0	Yes	Yes	Yes	No	6	7
55	5x39	5x42	d3_off	7.22	0	Yes	No	No	No	7	6
56	5x43	5x461	d3_off	4.89	0	No	No	No	No	8	8
57	5x54	6x41	d3_off	5.9	0	No	No	No	No	8	8
58	5x58	5x61	d3_off	9.67	0	Yes	Yes	No	No	9	9
59	5x58	6x38	d3_off	4	0	Yes	Yes	No	No	9	6
60	5x65	6x31	d3_off	4.23	0	No	No	No	No	8	7
61	6x26	6x27	d3_off	3.53	0	No	No	No	No	5	5
62	6x28	6x32	d3_off	8.46	0	No	No	No	No	5	8
63	6x36	7x53	d3_off	5.99	0	No	No	Yes	Yes	8	9
64	6x40	7x49	d3_off	5.91	0	No	No	No	No	8	9
65	6x40	7x52	d3_off	4.61	0	No	No	Yes	No	8	8
66	6x44	7x45	d3_off	7.25	0	Yes	Yes	No	No	9	9
67	6x48	6x51	d3_off	5.01	0	Yes	Yes	Yes	Yes	8	8
68	6x50	7x37	d3_off	3.5	0	No	No	No	No	9	6
69	6x51	7x34	d3_off	5.16	0	Yes	Yes	Yes	No	8	4
70	E3.C358	E3.V360	d3_off	3.42	0	No	No	No	No	4	5
71	7x34	7x37	d3_off	3.75	0	Yes	No	No	No	4	6
72	7x34	7x38	d3_off	6.24	0	Yes	No	No	No	4	6
73	7x39	7x43	d3_off	9.81	0	No	Yes	No	No	8	5
74	7x43	7x48	d3_off	4.47	0	No	No	No	No	5	7
75	7x49	7x53	d3_off	4.65	0	No	No	Yes	Yes	9	9
76	7x53	8x50	d3_off	6.19	0	Yes	Yes	Yes	Yes	9	9
77	4x42	4x46	d3_off	3.07	0	No	No	No	No	7	8
78	5x37	6x60	d3_off	3.05	0	No	No	No	No	4	4
79	2x53	2x57	d3_off	3.04	0	No	No	Yes	No	8	8
80	5x55	5x56	d3_off	2.98	0	No	No	No	No	5	4
81	1x43	1x44	d3_off	2.85	0	No	No	No	No	7	4
82	2x42	4x45	d3_off	2.83	0	No	No	No	No	7	6
83	3x31	3x34	d3_off	2.83	0	No	No	Yes	No	4	7
84	1x56	8x50	d3_off	2.77	0	No	No	Yes	Yes	9	9
85	5x60	5x63	d3_off	2.62	0	No	No	No	No	6	5
86	5x44	5x48	d3_off	2.54	0	No	No	No	No	8	6
87	1x57	2x41	d3_off	2.52	0	No	No	No	No	8	5
88	7x52	7x56	d3_off	2.51	0	Yes	No	No	No	8	7
89	3x52	I2x53	d3_off	2.5	0	No	No	Yes	Yes	5	8
90	2x48	4x50	d3_off	2.45	0	No	No	No	No	6	9
91	5x65	5x68	d3_off	2.43	0	No	No	No	No	8	7
92	2x66	2x67	d3_off	1.82	0	Yes	No	No	No	5	4
93	2x66	E1.G94	d3_off	1.82	0	Yes	No	No	No	5	5
94	1x54	2x47	d3_off	1.81	0	No	No	No	No	7	9
95	1x45	7x47	d3_off	1.79	0	No	No	No	No	4	6
96	2x49	3x38	d3_off	1.79	0	No	No	No	No	8	8
97	5x71	6x25	d3_off	1.74	0	No	No	No	No	4	4
98	3x21	3x24	d3_off	1.72	0	No	No	No	No	7	4
99	6x41	6x42	d3_off	1.71	0	No	No	No	No	8	6
100	2x57	2x58	d3_off	1.68	0	Yes	No	No	No	8	9
101	3x44	3x48	d3_off	1.64	0	Yes	No	No	No	7	6
102	5x44	5x45	d3_off	1.62	0	No	No	No	No	8	5
103	1x54	1x58	d3_off	1.59	0	No	No	No	No	7	4
104	I2x55	I2x56	d3_off	1.59	0	No	No	No	No	5	4
105	1x36	1x37	d3_off	1.58	0	No	No	No	No	7	6
106	3x27	4x62	d3_off	1.49	0	No	No	No	No	5	7
107	6x56	6x57	d3_off	1.49	0	No	No	No	No	6	6
108	4x38	I2.Q144	d3_off	1.44	0	No	No	No	No	8	5
109	7x54	8x51	d3_off	1.29	0	No	Yes	No	No	8	9
110	5x67	5x69	d3_off	1.17	0	No	No	No	No	5	5
111	1x35	7x35	Shared	6.36	1.69667	Yes	Yes	No	No	5	6
112	1x35	7x39	Shared	6.75	2.57333	Yes	Yes	No	Yes	5	8
113	1x39	2x60	Shared	5.05	5.04667	Yes	Yes	No	No	7	8
114	1x39	2x64	Shared	6.73	5.98667	Yes	Yes	No	No	7	6
115	1x39	7x39	Shared	7.72	6.11	Yes	Yes	No	Yes	7	8
116	1x42	1x46	Shared	4.28	4.76	No	No	Yes	Yes	7	8
117	1x43	2x57	Shared	4.37	6.80333	No	No	Yes	No	7	8
118	1x46	2x54	Shared	4.87	2.70333	Yes	Yes	No	No	8	8
119	1x50	2x47	Shared	4.69	3.64667	Yes	Yes	No	No	9	9
120	1x50	2x50	Shared	8.08	13.0133	Yes	Yes	No	Yes	9	9
121	1x50	2x51	Shared	4.12	4.58	Yes	Yes	No	No	9	8
122	1x50	7x50	Shared	9.77	6.51667	Yes	Yes	No	No	9	9
123	1x51	2x51	Shared	3.42	1.71	No	No	No	No	5	8
124	1x52	8x54	Shared	3.65	6.09	No	No	Yes	Yes	7	9
125	1x55	8x57	Shared	5.83	5.83333	No	No	No	No	5	7
126	1x57	2x44	Shared	4.81	4.81	No	No	No	No	8	7
127	1x60	I1x50	Shared	7.95	7.51	No	Yes	Yes	No	8	9
128	1x60	8x53	Shared	4.53	2.51667	No	Yes	No	No	8	8
129	2x40	I1x50	Shared	4.12	4.12	No	Yes	Yes	No	9	9
130	8x50	I1x50	Shared	7.31	11.3667	Yes	Yes	Yes	No	9	9
131	2x41	I1x51	Shared	7.89	1.12667	No	No	No	No	5	8
132	2x37	2x40	Shared	5.85	7.31	No	No	No	Yes	7	9
133	2x38	4x42	Shared	4.76	5.81667	No	No	No	No	6	7
134	2x40	8x50	Shared	6.04	8.05333	No	Yes	Yes	Yes	9	9
135	2x42	3x46	Shared	4.28	4.28333	No	No	No	No	7	9
136	2x45	3x42	Shared	10.43	7.94667	No	No	No	No	9	9
137	2x46	3x43	Shared	4.15	4.61333	No	No	No	No	9	8
138	2x50	7x46	Shared	11.78	8.83333	No	Yes	No	No	9	9
139	2x50	7x49	Shared	4.04	4.93667	No	Yes	No	No	9	9
140	2x52	3x35	Shared	7.07	8.01333	No	No	Yes	No	6	5
141	2x55	2x551	Shared	5.9	5.89667	No	No	No	No	5	6
142	2x56	3x32	Shared	7.3	7.3	No	No	No	No	8	8
143	2x57	7x42	Shared	8.38	7.98333	Yes	No	Yes	Yes	8	8
144	2x59	3x28	Shared	11.02	10.02	No	No	No	No	7	7
145	2x60	7x42	Shared	5.05	4.20667	No	No	Yes	Yes	8	8
146	2x62	2x66	Shared	3.75	4.99333	Yes	No	Yes	No	6	5
147	2x62	E1x52	Shared	12.38	5.15667	Yes	No	No	No	6	6
148	2x63	E1x50	Shared	4.56	3.79667	No	No	Yes	Yes	5	9
149	E1x50	E1x52	Shared	6.01	10.69	Yes	Yes	No	No	9	6
150	3x24	E1x50	Shared	3.92	3.92	No	No	Yes	Yes	4	9
151	3x25	E1x50	Shared	6.53	5.22333	No	No	Yes	Yes	9	9
152	E1x50	E2x50	Shared	14.37	11.7533	Yes	Yes	No	No	9	9
153	3x21	3x23	Shared	4.64	5.15667	No	No	No	No	7	4
154	3x22	3x25	Shared	6.96	6.96333	No	No	No	No	3	9
155	3x22	E2.T175	Shared	6.47	4.74333	No	No	No	No	3	4
156	3x25	E2x50	Shared	7.28	7.28	No	No	No	No	9	9
157	3x26	E2.N173	Shared	6.73	7.63	No	No	No	No	6	5
158	3x30	4x62	Shared	7.37	11.3	No	No	No	No	7	7
159	3x32	7x42	Shared	9.2	7.66667	No	No	Yes	Yes	8	8
160	3x32	Lig	Shared	21.08	16.55	No	No	Yes	Yes	8	0
161	3x33	4x57	Shared	6.46	4.31	No	No	No	No	8	8
162	3x33	Lig	Shared	8.41	14.2333	No	No	Yes	Yes	8	0
163	3x34	3x35	Shared	5.78	3.85	Yes	No	Yes	No	7	5
164	3x34	4x54	Shared	4.98	7.46667	Yes	No	No	No	7	6
165	3x34	4x57	Shared	6.13	5.11	Yes	No	No	No	7	8
166	3x36	6x48	Shared	9.14	4.78667	No	No	Yes	Yes	7	8
167	3x37	5x461	Shared	6.4	8.52667	No	No	No	No	8	8
168	3x38	4x50	Shared	6.48	5.18667	No	No	No	No	8	9
169	3x41	4x52	Shared	11.39	6	Yes	No	No	No	7	5
170	3x42	4x49	Shared	8.87	6.89667	No	No	No	No	9	7
171	3x44	5x53	Shared	3.42	3.42	Yes	No	No	No	7	7
172	3x44	5x54	Shared	3.38	3.94333	Yes	No	No	No	7	8
173	3x47	5x54	Shared	6.4	7.99333	No	No	No	No	9	8
174	3x47	5x58	Shared	5.09	8.90333	No	No	Yes	Yes	9	9
175	3x49	I2x53	Shared	10.34	9.96	Yes	No	Yes	Yes	9	8
176	3x51	3x55	Shared	7.57	11.3533	No	Yes	No	No	9	7
177	3x53	I2x53	Shared	9.34	10.2333	No	No	Yes	Yes	8	8
178	4x54	4x59	Shared	6.98	5.12333	No	No	No	No	6	6
179	4x56	5x46	Shared	6.41	2.67333	No	No	No	No	7	4
180	4x59	4x60	Shared	3.77	4.39333	No	No	No	No	6	7
181	4x59	4x63	Shared	5.59	2.79333	No	No	No	No	6	5
182	4x61	5x39	Shared	14.61	10.96	No	No	Yes	No	7	7
183	5x36	E2.T174	Shared	4.39	8.77333	Yes	Yes	No	No	6	5
184	E2.D177	E2.P178	Shared	8.05	7.51333	No	No	No	No	4	4
185	E2.D177	E2.T179	Shared	7.23	10.1167	No	No	No	No	4	2
186	5x36	5x37	Shared	6.52	4.89	Yes	Yes	No	No	6	4
187	5x40	6x55	Shared	4.15	12.9133	No	No	Yes	Yes	7	8
188	5x41	6x60	Shared	5.3	8.83667	No	No	No	No	6	4
189	5x43	Lig	Shared	8.48	6.91333	No	No	Yes	Yes	8	0
190	5x47	5x48	Shared	9.28	9.97333	No	Yes	No	No	9	6
191	5x47	6x49	Shared	3.65	6.90333	No	Yes	No	No	9	7
192	5x47	6x52	Shared	18.22	18.9333	No	Yes	No	Yes	9	7
193	5x51	5x55	Shared	3.93	6.55333	No	Yes	No	No	6	5
194	5x51	6x45	Shared	7.54	4.18667	No	Yes	No	No	6	5
195	5x58	6x37	Shared	3.79	6.31	Yes	Yes	No	No	9	8
196	5x62	5x66	Shared	9.55	14.33	No	No	No	No	6	6
197	5x63	5x67	Shared	4.3	0.476667	No	No	No	No	5	5
198	6x27	6x30	Shared	6.29	4.19333	No	No	No	Yes	5	8
199	6x41	6x45	Shared	4.28	4.76	No	No	No	No	8	5
200	6x44	6x48	Shared	17.04	7.01667	Yes	Yes	Yes	Yes	9	8
201	6x47	7x45	Shared	9.45	7.87333	No	No	No	No	8	9
202	6x48	6x52	Shared	5.01	6.68	Yes	Yes	No	Yes	8	7
203	6x48	7x41	Shared	9.85	1.87667	Yes	Yes	No	No	8	7
204	6x48	7x45	Shared	5.65	12.0533	Yes	Yes	No	No	8	9
205	6x49	6x53	Shared	5.54	2.30667	No	No	No	No	7	6
206	6x50	7x40	Shared	4.93	1.64333	No	No	No	No	9	8
207	6x51	6x55	Shared	12.44	4.14667	Yes	Yes	Yes	Yes	8	8
208	6x51	Lig	Shared	15.47	17.6833	Yes	Yes	Yes	Yes	8	0
209	6x52	Lig	Shared	8.6	6.54333	No	Yes	Yes	Yes	7	0
210	6x54	7x37	Shared	9.42	8.89667	No	No	No	No	6	6
211	6x55	7x34	Shared	9.8	5.80667	Yes	Yes	Yes	No	8	4
212	6x55	Lig	Shared	12.71	7.91	Yes	Yes	Yes	Yes	8	0
213	6x58	E3.V360	Shared	10.35	10.84	No	No	No	No	5	5
214	6x59	6x60	Shared	5.48	5.02	No	No	No	No	6	4
215	6x61	E3.C358	Shared	7.28	7.28	No	No	No	No	5	4
216	E3.Q356	E3.T357	Shared	12.76	5.19667	No	No	No	No	3	4
217	7x30	7x32	Shared	4.31	5.75	No	No	No	No	5	1
218	7x42	Lig	Shared	7.45	12.9	Yes	Yes	Yes	Yes	8	0
219	7x54	8x54	Shared	5.19	6.92	No	Yes	Yes	Yes	8	9
220	7x55	7x56	Shared	15.56	2.16	No	No	No	No	6	7
221	8x47	8x50	Shared	14.5	7.25	No	No	Yes	Yes	9	9
222	8x48	8x52	Shared	4.36	4.36333	No	No	No	No	5	6
223	8x50	8x54	Shared	9.65	10.3633	Yes	Yes	Yes	Yes	9	9
224	3x37	4x53	Shared	3.36	3.36	No	No	No	No	8	8
225	E2.S184	E2x51	Shared	3.26	0.543333	No	No	No	No	5	4
226	3x47	5x57	Shared	3.23	5.38667	No	No	No	No	9	7
227	3x54	5x64	Shared	3.21	2.67333	No	No	No	No	8	7
228	2x66	E1x49	Shared	3.17	4.23	Yes	No	No	No	5	3
229	2x45	4x46	Shared	3.1	4.64667	No	No	No	No	9	8
230	3x51	5x60	Shared	3.09	4.46	No	Yes	No	No	9	6
231	3x29	E2x52	Shared	3.07	7.17	No	No	No	No	7	7
232	2x53	3x35	Shared	3.04	4.05333	No	No	Yes	No	8	5
233	1x48	1x49	Shared	3.01	2.51	No	No	No	No	5	9
234	1x47	2x51	Shared	2.98	1.98667	No	No	No	No	6	8
235	3x29	E2.N173	Shared	2.96	3.45	No	No	No	No	7	5
236	6x39	7x52	Shared	2.94	1.96	No	No	Yes	No	8	8
237	1x52	8x57	Shared	2.85	1.42667	No	No	No	No	7	7
238	1x56	8x54	Shared	2.77	3.23333	No	No	Yes	Yes	9	9
239	2x52	2x551	Shared	2.77	2.30667	No	No	No	No	6	6
240	2x551	3x31	Shared	2.77	2.76667	No	No	No	No	6	4
241	1x57	8x50	Shared	2.62	2.62	No	No	Yes	Yes	8	9
242	5x60	5x64	Shared	2.62	5.66667	No	No	No	No	6	7
243	1x39	2x61	Shared	2.52	2.94333	Yes	Yes	No	No	7	6
244	3x51	5x57	Shared	2.52	4.21	No	Yes	No	No	9	7
245	2x67	E1.G94	Shared	2.11	2.11	No	No	No	No	4	5
246	E2.G176	E2.T175	Shared	1.82	3.03333	No	No	No	No	3	4
247	7x30	7x31	Shared	1.78	3.56	No	No	No	No	5	2
248	1x40	2x61	Shared	1.71	2.85	No	No	No	No	3	6
249	3x45	4x49	Shared	1.7	1.7	No	No	No	No	7	7
250	3x56	I2x50	Shared	1.68	1.12	No	No	No	No	6	8
251	1x46	7x47	Shared	1.62	2.70667	Yes	Yes	No	No	8	6
252	E2.V180	E2x51	Shared	1.62	1.62	No	No	No	No	4	4
253	5x44	6x56	Shared	1.62	3.23	No	No	No	No	8	6
254	6x43	7x52	Shared	1.62	1.62333	No	No	Yes	No	6	8
255	2x38	4x38	Shared	1.6	6.39667	No	No	No	No	6	8
256	4x47	4x51	Shared	1.59	1.59	No	No	No	No	4	5
257	7x51	7x55	Shared	1.59	5.29	No	No	No	No	6	6
258	7x30	7x33	Shared	1.5	1.5	No	No	No	No	5	5
259	3x27	3x31	Shared	1.49	2.98	No	No	No	No	5	4
260	6x54	7x33	Shared	1.47	4.42	No	No	No	No	6	5
261	5x36	5x38	Shared	1.35	3.59333	Yes	Yes	No	No	6	4
262	1x35	7x36	Shared	1.33	0.89	Yes	Yes	No	No	5	5
263	3x56	I2x52	Shared	1.31	4.81333	No	No	No	No	6	5
264	1x34	1x35	d3_on	0	3.64	No	No	Yes	Yes	0	5
265	1x42	7x39	d3_on	0	4.17667	No	No	No	Yes	7	8
266	1x42	7x43	d3_on	0	3.47667	No	No	No	No	7	5
267	1x46	1x50	d3_on	0	4.25	Yes	Yes	Yes	Yes	8	9
268	1x48	1x52	d3_on	0	3.65667	No	No	No	No	5	7
269	1x53	7x54	d3_on	0	6.87667	Yes	No	No	Yes	9	8
270	I1x48	I1x51	d3_on	0	4.28333	No	No	No	No	7	8
271	2x37	2x39	d3_on	0	5.75667	No	No	No	No	7	8
272	2x39	2x40	d3_on	0	4.87333	No	No	No	Yes	8	9
273	2x39	I2x53	d3_on	0	7.90667	No	No	Yes	Yes	8	8
274	2x42	3x49	d3_on	0	5.43	No	No	Yes	No	7	9
275	2x45	4x50	d3_on	0	5.35333	No	No	No	No	9	9
276	2x46	7x49	d3_on	0	5.03333	No	No	No	No	9	9
277	3x24	E1x52	d3_on	0	3.72333	No	No	No	No	4	6
278	3x22	E2.P178	d3_on	0	6.24333	No	No	No	No	3	4
279	3x29	4x61	d3_on	0	5.96	No	No	No	No	7	7
280	3x30	4x57	d3_on	0	4.8	No	No	No	No	7	8
281	3x33	4x61	d3_on	0	4.47	No	No	No	No	8	7
282	3x36	Lig	d3_on	0	8.37333	No	No	Yes	Yes	7	0
283	3x40	6x48	d3_on	0	14.8733	No	No	Yes	Yes	9	8
284	3x41	4x49	d3_on	0	6.45667	Yes	No	No	No	7	7
285	3x43	7x53	d3_on	0	5.86	No	No	Yes	Yes	8	9
286	3x44	5x50	d3_on	0	3.77	Yes	No	No	No	7	9
287	3x46	3x50	d3_on	0	4.59333	No	No	Yes	No	9	9
288	3x46	7x53	d3_on	0	6.04333	No	No	Yes	Yes	9	9
289	3x49	4x41	d3_on	0	3.97	Yes	No	No	Yes	9	7
290	3x50	5x58	d3_on	0	7.2	Yes	No	Yes	Yes	9	9
291	3x51	5x61	d3_on	0	6.04333	No	Yes	No	No	9	9
292	3x52	4x41	d3_on	0	4.74333	No	No	No	Yes	5	7
293	4x41	I2x53	d3_on	0	5.14333	No	Yes	Yes	Yes	7	8
294	I2x54	I2x55	d3_on	0	4.53333	No	No	No	No	6	5
295	4x40	I2.Q144	d3_on	0	8.56667	No	No	No	No	5	5
296	4x38	4x41	d3_on	0	7.46667	No	No	No	Yes	8	7
297	5x39	E2.F172	d3_on	0	4.28667	Yes	No	No	No	7	6
298	5x39	5x43	d3_on	0	12.77	Yes	No	No	No	7	8
299	5x40	6x59	d3_on	0	13.75	No	No	No	No	7	6
300	5x44	6x52	d3_on	0	5.28	No	No	No	Yes	8	7
301	5x44	6x55	d3_on	0	4.18	No	No	Yes	Yes	8	8
302	5x461	Lig	d3_on	0	4.68	No	No	Yes	Yes	8	0
303	5x47	5x51	d3_on	0	17.8633	No	Yes	No	Yes	9	6
304	5x47	6x44	d3_on	0	5.00333	No	Yes	Yes	Yes	9	9
305	5x49	5x50	d3_on	0	3.83	No	No	No	No	7	9
306	5x51	6x44	d3_on	0	7.5	No	Yes	Yes	Yes	6	9
307	5x54	6x44	d3_on	0	4.75333	No	No	Yes	Yes	8	9
308	5x55	6x41	d3_on	0	3.47667	No	No	No	No	5	8
309	5x58	6x40	d3_on	0	6.73	Yes	Yes	No	No	9	8
310	5x62	6x34	d3_on	0	6.65667	No	No	No	No	6	8
311	5x66	5x70	d3_on	0	5.77667	No	No	No	No	6	6
312	5x69	6x30	d3_on	0	17.8333	No	No	No	Yes	5	8
313	5x72	6x30	d3_on	0	3.87667	No	No	No	Yes	0	8
314	6x36	7x56	d3_on	0	6.63667	No	No	No	No	8	7
315	6x40	7x53	d3_on	0	4.62667	No	No	Yes	Yes	8	9
316	6x51	6x52	d3_on	0	7.14333	Yes	Yes	No	Yes	8	7
317	6x51	7x37	d3_on	0	3.89	Yes	Yes	No	No	8	6
318	6x51	7x38	d3_on	0	4.32333	Yes	Yes	No	No	8	6
319	7x38	Lig	d3_on	0	4.65	No	No	Yes	Yes	6	0
320	7x45	7x49	d3_on	0	11.35	No	No	No	No	9	9
321	7x52	7x53	d3_on	0	5.64333	Yes	No	Yes	Yes	8	9
322	7x54	8x50	d3_on	0	14.2667	No	Yes	Yes	Yes	8	9
323	8x47	8x49	d3_on	0	7.01	No	No	No	No	9	7
324	2x58	2x59	d3_on	0	3.60333	No	No	No	No	9	7
325	5x36	E2.F172	d3_on	0	5.23667	Yes	Yes	No	No	6	6
326	5x66	6x30	d3_on	0	3.6	No	No	No	Yes	6	8
327	6x53	6x57	d3_on	0	4.15333	No	No	No	No	6	6
328	7x31	7x32	d3_on	0	6.28667	No	No	No	No	2	1
329	E1x49	E1x51	d3_on	0	3.44667	No	No	No	No	3	4
330	2x38	4x39	d3_on	0	3.38	No	No	No	No	6	4
331	2x42	4x46	d3_on	0	3.33	No	No	No	No	7	8
332	4x41	4x45	d3_on	0	3.30667	No	Yes	No	No	7	6
333	6x49	6x50	d3_on	0	3.28333	No	No	No	No	7	9
334	I2.S145	I2x52	d3_on	0	3.25	No	No	No	No	7	5
335	6x35	6x39	d3_on	0	3.20333	No	No	No	No	7	8
336	6x47	7x48	d3_on	0	3.17333	No	No	No	No	8	7
337	6x58	7x34	d3_on	0	3.1	No	No	Yes	No	5	4
338	3x28	E1x50	d3_on	0	3.00667	No	No	Yes	Yes	7	9
339	2x41	4x42	d3_on	0	2.94333	No	No	No	No	5	7
340	2x50	3x39	d3_on	0	2.94333	No	Yes	No	No	9	9
341	8x48	8x51	d3_on	0	2.92333	No	No	No	No	5	9
342	3x48	4x45	d3_on	0	2.91667	No	No	No	No	6	6
343	1x38	7x39	d3_on	0	2.88333	No	No	No	Yes	4	8
344	5x61	5x65	d3_on	0	2.85	No	No	No	No	9	8
345	2x60	3x28	d3_on	0	2.62	No	No	No	No	8	7
346	1x60	I1x49	d3_on	0	2.51667	No	Yes	No	No	8	6
347	3x52	3x56	d3_on	0	2.51	No	No	No	No	5	6
348	5x51	5x52	d3_on	0	2.51	No	Yes	No	No	6	4
349	2x48	2x52	d3_on	0	2.48333	No	No	No	No	6	6
350	4x52	4x56	d3_on	0	2.48333	No	No	No	No	5	7
351	I2x57	I2x58	d3_on	0	2.42667	No	No	No	No	6	3
352	6x42	6x45	d3_on	0	2.35333	No	No	No	No	6	5
353	2x49	3x39	d3_on	0	2.28	No	No	No	No	8	9
354	2x63	E1.G94	d3_on	0	2.28	No	No	No	No	5	5
355	5x41	5x42	d3_on	0	2.01667	No	No	No	No	6	6
356	I2x51	I2x52	d3_on	0	1.84333	No	No	No	No	6	5
357	I2x56	I2x57	d3_on	0	1.82	No	No	No	No	4	6
358	1x60	8x56	d3_on	0	1.8	No	Yes	No	No	8	6
359	1x36	2x65	d3_on	0	1.7	No	No	No	No	7	5
360	6x39	7x56	d3_on	0	1.67333	No	No	No	No	8	7
361	2x61	2x65	d3_on	0	1.6	No	No	No	No	6	5
362	2x43	7x54	d3_on	0	1.59	No	No	No	Yes	8	8
363	6x57	6x61	d3_on	0	1.58667	No	No	No	No	6	5
364	6x57	E3.C358	d3_on	0	1.58667	No	No	No	No	6	4
365	5x41	5x45	d3_on	0	1.54	No	No	No	No	6	5
366	E2.D177	E2.V180	d3_on	0	1.46	No	No	No	No	4	4
367	6x32	6x36	d3_on	0	1.44	No	No	No	No	8	8
368	1x55	1x59	d3_on	0	1.44	No	No	No	No	5	5
369	5x65	6x30	d3_on	0	1.32667	No	No	No	Yes	8	8
370	1x51	1x54	d3_on	0	1.30667	No	No	No	No	5	7
371	5x69	5x73	d3_on	0	1.25333	No	No	No	No	5	0
372	4x38	I2x56	d3_on	0	1.24	No	No	No	No	8	4
373	6x46	6x47	d3_on	0	1.14	No	No	No	No	4	8
374	4x64	E2.N173	d3_on	0	1.13333	No	No	No	No	5	5
375	3x23	3x27	d3_on	0	1.02667	No	No	No	No	4	5
376	5x56	5x57	d3_on	0	0.993333	No	No	No	No	4	7
377	I2x51	I2x54	d3_on	0	0.956667	No	No	No	No	6	6
378	8x47	8x48	d3_on	0	0.946667	No	No	No	No	9	5
379	5x67	5x70	d3_on	0	0.78	No	No	No	No	5	6
380	5x68	5x72	d3_on	0	0.713333	No	No	No	No	7	0
381	8x56	CT.C400	d3_on	0	0.54	No	No	No	No	6	9
382	4x52	4x55	d3_on	0	0.526667	No	No	No	No	5	5
383	5x65	6x33	d3_on	0	0.526667	No	No	No	No	8	8
384	4x39	I2.Q144	d3_on	0	0.51	No	No	No	No	4	5
385	1x44	1x47	d3_on	0	0.496667	No	No	No	No	4	6
386	6x28	6x31	d3_on	0	0.47	No	No	No	No	5	7
387	8x55	8x58	d3_on	0	0.46	No	No	No	No	5	7
388	5x67	5x71	d3_on	0	0.453333	No	No	No	No	5	4
389	6x30	6x31	d3_on	0	0.45	No	Yes	No	No	8	7
390	8x51	8x55	d3_on	0	0.403333	No	No	No	No	9	5

Orange: nodes, hubs and links specific of d3_off network

Green: nodes, hubs and links shared by both networks

Purple: nodes, hubs and links specific of d3_on network

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Owner: the name of the network the hub belong to or "Shared" if the corresponding hub is present in both networks.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub in the corresponding network.

Num Of Links: the number of links of the corresponding hub in the corresponding network.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Owner	d3_off Avg Int. Strength	d3_on Avg Int. Strength	d3_off Num Of Links	d3_on Num Of Links	ConSurf
1	1x53	d3_off	3.66	6.87667	4	1	9
2	I1x50	d3_off	6.8325	7.66556	4	3	9
3	2x57	d3_off	4.342	7.39333	5	2	8
4	2x62	d3_off	5.864	5.075	5	2	6
5	2x66	d3_off	2.64	4.61167	4	2	5
6	3x34	d3_off	4.93	5.47556	4	3	7
7	3x35	d3_off	5.135	5.30556	4	3	5
8	3x41	d3_off	10.318	6.22833	5	2	7
9	3x44	d3_off	3.09	3.71111	4	3	7
10	3x49	d3_off	7.5625	6.45333	4	3	9
11	3x50	d3_off	7.64857	5.89667	7	2	9
12	5x39	d3_off	7.8075	9.33889	4	3	7
13	7x34	d3_off	6.2375	4.45333	4	2	4
14	7x52	d3_off	2.92	3.07556	4	3	8
15	1x35	Shared	5.028	2.2	5	4	5
16	1x39	Shared	5.198	5.02167	5	4	7
17	1x46	Shared	4.24	3.605	4	4	8
18	1x50	Shared	6.665	6.40133	4	5	9
19	E1x50	Shared	6.54167	6.39833	6	6	9
20	I2x53	Shared	7.84	8.31083	6	4	8
21	5x36	Shared	3.97	5.62333	4	4	6
22	5x58	Shared	5.6375	7.28583	4	4	9
23	6x44	Shared	8.132	6.06833	5	4	9
24	6x48	Shared	8.61667	7.88111	6	6	8
25	6x51	Shared	9.52	7.43733	4	5	8
26	6x55	Shared	9.775	6.99133	4	5	8
27	7x42	Shared	6.774	8.18917	5	4	8
28	7x53	Shared	6.396	5.54333	5	4	9
29	8x50	Shared	7.01143	8.98667	7	6	9
30	8x54	Shared	5.038	6.65167	5	4	9
31	Lig	Shared	12.29	10.0437	8	10	0
32	1x60	d3_on	6.24	3.58583	2	4	8
33	2x40	d3_on	5.33667	6.08917	3	4	9
34	2x50	d3_on	7.96667	7.43167	3	4	9
35	3x51	d3_on	4.39333	6.51667	3	4	9
36	4x41	d3_on	0	4.926	0	5	7
37	5x47	d3_on	10.3833	11.7353	3	5	9
38	5x51	d3_on	5.735	7.72267	2	5	6
39	6x30	d3_on	6.68	5.21333	3	6	8
40	6x52	d3_on	10.61	8.916	3	5	7
41	7x39	d3_on	8.09333	3.93583	3	4	8
42	7x54	d3_on	3.24	7.41333	2	4	8

Orange: nodes, hubs and links specific of d3_off network

Green: nodes, hubs and links shared by both networks

Purple: nodes, hubs and links specific of d3_on network

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Owner: the name of the network the link belong to or "Shared" if the corresponding link is present in both networks.

Recurrence: the relative Recurrence in the filtered pool of shortest paths.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Owner	d3_off Recurrence	d3_on Recurrence	d3_off Hub1?	d3_on Hub1?	d3_off Hub2?	d3_on Hub2?	ConSurf1	ConSurf2
1	1x39	2x60	d3_off	13.2581	8.5419	Yes	Yes	No	No	7	8
2	2x57	7x42	d3_off	76.2222	3.04084	Yes	No	Yes	Yes	8	8
3	1x42	2x57	d3_off	74.5571	0	No	No	Yes	No	7	8
4	1x42	1x46	d3_off	73.7324	5.2683	No	No	Yes	Yes	7	8
5	1x46	7x46	d3_off	70.3547	0	Yes	Yes	No	No	8	9
6	2x50	7x46	d3_off	69.4906	0.848433	No	Yes	No	No	9	9
7	1x50	7x50	d3_off	11.8494	0.845931	Yes	Yes	No	No	9	9
8	1x50	2x47	d3_off	11.8494	0.845931	Yes	Yes	No	No	9	9
9	1x53	8x54	d3_off	21.2445	0	Yes	No	Yes	Yes	9	9
10	1x52	8x54	d3_off	13.9328	9.55801	No	No	Yes	Yes	7	9
11	7x49	7x53	d3_off	34.3448	0	No	No	Yes	Yes	9	9
12	7x53	8x50	d3_off	23.8646	0	Yes	Yes	Yes	Yes	9	9
13	6x51	Lig	d3_off	56.7218	1.46912	Yes	Yes	Yes	Yes	8	0
14	6x48	6x51	d3_off	53.9321	0	Yes	Yes	Yes	Yes	8	8
15	3x43	6x44	d3_off	55.3328	0	No	No	Yes	Yes	8	9
16	2x46	3x42	d3_off	52.5628	0	No	No	No	No	9	9
17	4x42	4x46	d3_off	45.4997	0	No	No	No	No	7	8
18	2x38	4x42	d3_off	44.0358	6.49715	No	No	No	No	6	7
19	2x38	3x49	d3_off	36.8465	0	No	No	Yes	No	6	9
20	3x49	3x50	d3_off	16.8883	0	Yes	No	Yes	No	9	9
21	3x40	6x44	d3_off	53.2494	0	No	No	Yes	Yes	9	9
22	3x40	3x41	d3_off	50.3176	0	No	No	Yes	No	9	7
23	3x41	3x44	d3_off	46.1863	0	Yes	No	Yes	No	7	7
24	3x44	5x54	d3_off	41.8538	4.85284	Yes	No	No	No	7	8
25	2x53	2x57	d3_off	15.8466	0	No	No	Yes	No	8	8
26	2x53	3x35	d3_off	14.7299	1.60927	No	No	Yes	No	8	5
27	E2x52	Lig	d3_off	36.3848	0	No	No	Yes	Yes	7	0
28	3x29	E2x52	d3_off	35.3825	1.46661	No	No	No	No	7	7
29	3x29	E2.N173	d3_off	32.143	4.81279	No	No	No	No	7	5
30	3x22	E2.N173	d3_off	29.7597	0	No	No	No	No	3	5
31	2x62	E1x50	d3_off	12.0704	0	Yes	No	Yes	Yes	6	9
32	5x43	5x461	d3_off	15.8466	0	No	No	No	No	8	8
33	3x37	5x461	d3_off	14.6234	3.21604	No	No	No	No	8	8
34	3x37	4x56	d3_off	12.1848	0	No	No	No	No	8	7
35	3x50	6x30	d3_off	10.8551	0	Yes	No	No	Yes	9	8
36	6x30	I2x53	d3_off	10.9892	0	No	Yes	Yes	Yes	8	8
37	3x51	5x60	d3_off	14.5129	3.52888	No	Yes	No	No	9	6
38	6x27	6x30	d3_off	19.0072	1.21884	No	No	No	Yes	5	8
39	6x26	6x27	d3_off	12.8122	0	No	No	No	No	5	5
40	6x51	7x34	d3_off	10.0896	0	Yes	Yes	Yes	No	8	4
41	7x34	7x37	d3_off	13.6606	0	Yes	No	No	No	4	6
42	2x60	7x42	Shared	14.4458	42.5718	No	No	Yes	Yes	8	8
43	1x50	2x50	Shared	27.2304	10.6042	Yes	Yes	No	Yes	9	9
44	2x50	7x49	Shared	42.5206	12.9768	No	Yes	No	No	9	9
45	7x42	Lig	Shared	83.4708	46.1933	Yes	Yes	Yes	Yes	8	0
46	6x44	6x48	Shared	100	54.5625	Yes	Yes	Yes	Yes	9	8
47	2x46	3x43	Shared	53.9518	45.46	No	No	No	No	9	8
48	2x45	3x42	Shared	48.3487	12.9317	No	No	No	No	9	9
49	2x45	4x46	Shared	46.9281	17.6995	No	No	No	No	9	8
50	6x52	Lig	Shared	56.0036	65.5846	No	Yes	Yes	Yes	7	0
51	6x48	6x52	Shared	52.7562	56.8075	Yes	Yes	No	Yes	8	7
52	3x47	5x54	Shared	31.4683	83.5569	No	No	No	No	9	8
53	3x47	5x58	Shared	11.3325	64.9114	No	No	Yes	Yes	9	9
54	3x22	3x25	Shared	22.4007	13.9103	No	No	No	No	3	9
55	3x25	E1x50	Shared	19.824	15.422	No	No	Yes	Yes	9	9
56	3x34	3x35	Shared	12.5202	15.89	Yes	No	Yes	No	7	5
57	3x33	Lig	Shared	18.8297	38.1219	No	No	Yes	Yes	8	0
58	3x33	4x57	Shared	17.7643	28.2436	No	No	No	No	8	8
59	3x34	4x57	Shared	16.9278	23.6485	Yes	No	No	No	7	8
60	5x43	Lig	Shared	16.9514	10.7143	No	No	Yes	Yes	8	0
61	3x49	I2x53	Shared	17.0501	47.242	Yes	No	Yes	Yes	9	8
62	3x47	5x57	Shared	19.2716	28.5789	No	No	No	No	9	7
63	3x51	5x57	Shared	17.6932	26.3715	No	Yes	No	No	9	7
64	2x46	7x49	d3_on	0	45.8179	No	No	No	No	9	9
65	3x43	7x53	d3_on	0	45.1121	No	No	Yes	Yes	8	9
66	3x46	7x53	d3_on	0	41.0251	No	No	Yes	Yes	9	9
67	2x42	3x46	d3_on	3.16064	100	No	No	No	No	7	9
68	2x42	3x49	d3_on	0	82.7786	No	No	Yes	No	7	9
69	2x39	I2x53	d3_on	0	46.0757	No	No	Yes	Yes	8	8
70	2x39	2x40	d3_on	0	43.0323	No	No	No	Yes	8	9
71	2x40	8x50	d3_on	2.60427	32.3306	No	Yes	Yes	Yes	9	9
72	8x50	8x54	d3_on	7.91145	12.5538	Yes	Yes	Yes	Yes	9	9
73	3x49	4x41	d3_on	0	34.1651	Yes	No	No	Yes	9	7
74	4x38	4x41	d3_on	0	19.1035	No	No	No	Yes	8	7
75	2x38	4x38	d3_on	6.5817	12.9092	No	No	No	No	6	8
76	2x42	4x46	d3_on	0	19.2787	No	No	No	No	7	8
77	2x52	3x35	d3_on	2.93967	12.7515	No	No	Yes	No	6	5
78	2x60	3x28	d3_on	0	36.2974	No	No	No	No	8	7
79	3x28	E1x50	d3_on	0	32.0202	No	No	Yes	Yes	7	9
80	3x36	Lig	d3_on	0	40.3269	No	No	Yes	Yes	7	0
81	3x36	6x48	d3_on	1.66121	40.6447	No	No	Yes	Yes	7	8
82	3x42	4x49	d3_on	3.31847	11.3325	No	No	No	No	9	7
83	5x54	6x44	d3_on	0	86.8355	No	No	Yes	Yes	8	9
84	5x47	6x52	d3_on	8.67695	34.8408	No	Yes	No	Yes	9	7
85	5x47	6x44	d3_on	0	32.5458	No	Yes	Yes	Yes	9	9
86	3x46	3x50	d3_on	0	60.4515	No	No	Yes	No	9	9
87	3x51	5x61	d3_on	0	20.878	No	Yes	No	No	9	9
88	3x52	4x41	d3_on	0	12.9167	No	No	No	Yes	5	7
89	3x52	3x56	d3_on	0	11.33	No	No	No	No	5	6
90	6x55	Lig	d3_on	7.8641	15.8024	Yes	Yes	Yes	Yes	8	0
91	5x40	6x55	d3_on	1.02592	19.519	No	No	Yes	Yes	7	8
92	5x40	6x59	d3_on	0	16.2779	No	No	No	No	7	6
93	6x59	6x60	d3_on	1.36527	13.0318	No	No	No	No	6	4
94	5x44	6x52	d3_on	0	10.3339	No	No	No	Yes	8	7
95	5x61	5x65	d3_on	0	19.7342	No	No	No	No	9	8
96	5x65	6x30	d3_on	0	17.6644	No	No	No	Yes	8	8
97	7x45	7x49	d3_on	0	46.8015	No	No	No	No	9	9
98	8x47	8x50	d3_on	1.36921	11.3325	No	No	Yes	Yes	9	9
99	3x50	5x58	d3_on	0	61.0997	Yes	No	Yes	Yes	9	9
100	6x48	7x45	d3_on	2.73448	48.3332	Yes	Yes	No	No	8	9
101	6x51	6x52	d3_on	0	14.9264	Yes	Yes	No	Yes	8	7

Here, those paths that begin and end at given residue pair(s) or that pass through a residue are used to generate a novel metapath. Such a path filtering is particularly recommended if some information on allosteric residues is available. The selection syntax for a residue pair ("Pairs") is C:C:c534,A:A:?600 (the lower-case "c" stands for cytosine and "?" indicates any non standard amino acid or nucleotide residue). Selection of more than one apical residue pair has the following syntax: C:C:c534,A:A:?600,C:C:c534,A:A:E41. Only one residue can be selected as a tail ("Tail"). For midway residue(s), each residue must be separated by a comma as well e.g. A:A:?600,A:A:E41.

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Node1	Node2	Owner	Net1LinkStrength	Net2LinkStrength	Comm1	Comm2	Node1Shell	Node2Shell
2x56	3x32	Shared	7.3	7.3	1	0	2	1
2x56	7x42	d3_off	3.79	0	1	0	2	1
2x57	7x42	Shared	8.38	7.98333	0	0	2	1
2x60	7x42	Shared	5.05	4.20667	0	0	2	1
3x32	7x42	Shared	9.2	7.66667	1	2	1	1
3x32	Lig	Shared	21.08	16.55	1	2	1	0
3x33	4x57	Shared	6.46	4.31	0	0	1	2
3x33	Lig	Shared	8.41	14.2333	0	0	1	0
3x36	6x48	Shared	9.14	4.78667	0	0	1	2
3x37	5x461	Shared	6.4	8.52667	0	0	2	1
4x61	5x39	Shared	14.61	10.96	0	0	2	2
E2x52	Lig	d3_off	16.12	0	0	0	1	0
5x40	6x55	Shared	4.15	12.9133	0	0	2	1
5x43	5x461	d3_off	4.89	0	0	0	1	1
5x43	Lig	Shared	8.48	6.91333	0	0	1	0
5x47	6x52	Shared	18.22	18.9333	0	2	2	1
6x48	6x51	d3_off	5.01	0	1	0	2	1
6x48	6x52	Shared	5.01	6.68	1	0	2	1
6x51	6x55	Shared	12.44	4.14667	1	2	1	1
6x51	7x34	d3_off	5.16	0	1	2	1	2
6x51	Lig	Shared	15.47	17.6833	1	2	1	0
6x52	Lig	Shared	8.6	6.54333	0	2	1	0
6x55	7x34	Shared	9.8	5.80667	1	2	1	2
6x55	Lig	Shared	12.71	7.91	1	2	1	0
7x34	7x37	d3_off	3.75	0	1	0	2	2
7x34	7x38	d3_off	6.24	0	1	0	2	1
7x42	Lig	Shared	7.45	12.9	1	2	1	0
3x29	E2x52	Shared	3.07	7.17	0	0	2	1
3x29	4x61	d3_on	0	5.96	0	0	2	2
3x33	4x61	d3_on	0	4.47	0	0	1	2
3x36	Lig	d3_on	0	8.37333	0	0	1	0
5x39	5x43	d3_on	0	12.77	0	0	2	1
5x44	6x52	d3_on	0	5.28	0	0	2	1
5x44	6x55	d3_on	0	4.18	0	0	2	1
5x461	Lig	d3_on	0	4.68	0	0	1	0
6x51	6x52	d3_on	0	7.14333	1	2	1	1
6x51	7x37	d3_on	0	3.89	1	2	1	2
6x51	7x38	d3_on	0	4.32333	1	2	1	1
7x38	Lig	d3_on	0	4.65	0	2	1	0

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Difference Members
	Id	Description
	d3_off	3PBL-D₃-Eticlopride
	d3_on	8IRT-D₃-Rotigotine-Gi1/&β;1/&γ;2 7CMV-D₃-PD128907-Gi1/&β;1/&γ;2 7CMU-D₃-Pramipexole-Gi1/&β;1/&γ;2

Network Difference
Value	d3_off	d3_on
I_min	3.38	3.45
Number of Linked Nodes	245	262
Number of Specific Nodes	6 (2.45%)	23 (8.78%)
Number of Shared Nodes	239 (97.55%)	239 (91.22%)
Number of Links	263	280
Number of Specific Links	110 (41.83%)	127 (45.36%)
Number of Shared Links	153 (58.17%)	153 (54.64%)
Number of Hubs	31	28
Number of Specific Hubs	14 (45.16%)	11 (39.29%)
Number of Shared Hubs	17 (54.84%)	17 (60.71%)
Average % Shared Neighbours (Jaccard)	41.45
Average % Shared Neighbours (Otsuka)	51.38
Average % Shared Neighbours (Overlap Coefficient)	61.77
Average % Shared Cliques (k3-6)	78.70
Graphlets Similarity	0.485804

Paths Difference
Value	d3_off	d3_on
Number Of Nodes in MetaPath	62	58
Specific Nodes in MetaPath	26 (41.94%)	22 (37.93%)
Shared Nodes in MetaPath	239 (97.55%)	239 (97.55%)
Number Of Links MetaPath	63	60
Specific Links in MetaPath	41 (65.08%)	38 (63.33%)
Shared Links in MetaPath	153 (58.17%)	153 (58.17%)
Number of Shortest Paths	46612	72035
Length Of Smallest Path	3	3
Average Path Length	15.6462	15.7659
Length of Longest Path	32	31
Minimum Path Strength	1.485	0.431667
Average Path Strength	6.39869	6.39634
Maximum Path Strength	19.205	18.3983
Minimum Path Correlation	0.7	0.7
Average Path Correlation	0.919694	0.922216
Maximum Path Correlation	0.99	0.99
Minimum % Of Corr. Nodes	3.7037	3.44828
Average % Of Corr. Nodes	43.7032	40.0821
Maximum % Of Corr. Nodes	100	100
Minimum Path Hubs %	0	0
Average Path Hubs %	40.2361	34.8925
Maximum Path Hubs %	100	100

Details about the values in these tables can be found in the corresponding documentation page .

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