Orange: nodes, hubs and links specific of dop_on_gp network

Green: nodes, hubs and links shared by both networks

Purple: nodes, hubs and links specific of dop_off network

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Owner: the name of the network the hub belong to or "Shared" if the corresponding hub is present in both networks.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub in the corresponding network.

Num Of Links: the number of links of the corresponding hub in the corresponding network.

ConSurf: this column reports the ConSurf conservation grades of each hub.


Index Hub Owner dop_on_gp Avg Int. Strength dop_off Avg Int. Strength dop_on_gp Num Of Links dop_off Num Of Links ConSurf
11x36 dop_on_gp4.8056.18667436
21x53 dop_on_gp3.24255.05418
32x41 dop_on_gp2.952.46333436
42x44 dop_on_gp6.59254.385426
52x56 dop_on_gp3.20255.22667437
62x60 dop_on_gp7.5359.705425
72x64 dop_on_gp6.49257.78424
83x40 dop_on_gp2.767.78427
9I2x57 dop_on_gp6.0583311.795626
10E2x50 dop_on_gp5.64256.09667439
11E2x52 dop_on_gp43.52414
125x40 dop_on_gp8.5056.66667435
13I3 dop_on_gp5.9301103
146x52 dop_on_gp4.13758.12667437
15E3 dop_on_gp11.24211.8333532
167x35 dop_on_gp5.99411.98514
177x49 dop_on_gp5.77.435429
187x51 dop_on_gp3.51750406
198x50 dop_on_gp6.08257.21667438
20G.HN.43 dop_on_gp3.9250409
21G.HN.47 dop_on_gp3.096670606
22G.S1.02 dop_on_gp4.770505
23G.S1.04 dop_on_gp4.450407
24G.S1.06 dop_on_gp7.6350408
25G.S1.07 dop_on_gp4.480409
26G.s1h1.06 dop_on_gp2.65750409
27G.H1.01 dop_on_gp5.8350409
28G.S2.01 dop_on_gp3.8450409
29G.S3.01 dop_on_gp4.50750404
30G.S3.03 dop_on_gp7.5620507
31G.S3.04 dop_on_gp8.2960506
32G.S3.05 dop_on_gp3.92750407
33G.S3.06 dop_on_gp6.4660505
34G.H2.02 dop_on_gp4.3350408
35G.H2.03 dop_on_gp5.110409
36G.H2.06 dop_on_gp5.851670609
37G.H2.07 dop_on_gp6.6720509
38G.h2s4.01 dop_on_gp4.895710709
39G.S4.02 dop_on_gp5.36750408
40G.S4.03 dop_on_gp4.30507
41G.S4.04 dop_on_gp5.2250609
42G.H3.01 dop_on_gp8.050409
43G.H3.09 dop_on_gp6.7150409
44G.H3.15 dop_on_gp5.230408
45G.H3.17 dop_on_gp7.191670605
46G.H3.18 dop_on_gp8.19750409
47G.S5.03 dop_on_gp4.3460508
48G.S5.05 dop_on_gp4.148570709
49G.S5.06 dop_on_gp4.640408
50G.S5.07 dop_on_gp4.170409
51G.HG.04 dop_on_gp5.086670609
52G.HG.15 dop_on_gp5.08750407
53G.hgh4.02 dop_on_gp3.6840507
54G.hgh4.05 dop_on_gp9.10750407
55G.H4.03 dop_on_gp3.9650404
56G.H4.15 dop_on_gp3.3250608
57G.h4s6.02 dop_on_gp6.44250408
58G.S6.02 dop_on_gp6.7650607
59G.S6.03 dop_on_gp5.7350405
60G.s6h5.01 dop_on_gp5.660409
61G.H5.03 dop_on_gp6.59750408
62G.H5.08 dop_on_gp6.9740508
63G.H5.26 dop_on_gp3.47250405
64b.h2x5 dop_on_gp4.09250405
65b.lhb1x3 dop_on_gp3.11250402
66b.lhb1x6 dop_on_gp5.72250403
67b.lhb1x11 dop_on_gp3.91250404
68b.b1x3 dop_on_gp4.35750407
69b.l1x3 dop_on_gp7.122860709
70b.b2x5 dop_on_gp6.0250607
71b.b4x2 dop_on_gp6.050408
72b.b4x4 dop_on_gp7.760408
73b.b4x6 dop_on_gp9.186670609
74b.l4x2 dop_on_gp4.720404
75b.b5x2 dop_on_gp5.920407
76b.b5x3 dop_on_gp6.1750609
77b.b5x5 dop_on_gp5.040405
78b.b5x7 dop_on_gp5.31750407
79b.l5x1 dop_on_gp6.0360508
80b.l5x5 dop_on_gp6.705710709
81b.b6x5 dop_on_gp4.383330606
82b.l6x5 dop_on_gp6.88750404
83b.b7x1 dop_on_gp6.1320504
84b.b8x3 dop_on_gp3.190506
85b.b8x4 dop_on_gp5.4150606
86b.b9x2 dop_on_gp3.07750405
87b.l9x3 dop_on_gp6.014290709
88b.l9x6 dop_on_gp5.888330608
89b.b10x5 dop_on_gp5.218330609
90b.b11x6 dop_on_gp6.3250409
91b.l11x1 dop_on_gp3.80409
92b.l11x2 dop_on_gp8.480409
93b.b12x6 dop_on_gp7.061430708
94b.l12x1 dop_on_gp2.7250406
95b.b13x7 dop_on_gp6.7380507
96b.l13x3 dop_on_gp7.156670609
97b.l13x6 dop_on_gp5.360509
98b.b15x1 dop_on_gp5.7160509
99b.b15x2 dop_on_gp5.50250406
100b.l15x1 dop_on_gp5.0450607
101b.l15x2 dop_on_gp5.4250409
102b.b16x4 dop_on_gp9.510406
103b.b16x5 dop_on_gp5.1650405
104b.b16x6 dop_on_gp8.511670608
105b.b16x7 dop_on_gp8.51750409
106b.b17x5 dop_on_gp7.220507
107b.b17x7 dop_on_gp7.3850408
108b.l17x3 dop_on_gp7.203750809
109b.l17x6 dop_on_gp6.240409
110b.b18x3 dop_on_gp4.32250408
111b.l18x1 dop_on_gp7.738330606
112b.b19x2 dop_on_gp4.544290706
113b.b19x4 dop_on_gp5.7840508
114b.l19x2 dop_on_gp7.64750409
115b.b20x2 dop_on_gp5.680506
116b.b20x4 dop_on_gp11.0950408
117b.b20x6 dop_on_gp6.5920506
118b.b20x7 dop_on_gp4.9050409
119b.l20x2 dop_on_gp5.83750409
120b.b21x1 dop_on_gp11.2250407
121b.b21x5 dop_on_gp4.9950404
122b.b21x7 dop_on_gp3.934290705
123b.l21x5 dop_on_gp3.31750404
124b.b22x5 dop_on_gp5.523330607
125b.l22x5 dop_on_gp6.6460509
126b.b23x1 dop_on_gp4.71750405
127b.b23x6 dop_on_gp6.047140707
128b.l23x1 dop_on_gp7.40406
129b.b24x4 dop_on_gp5.6620506
130b.b24x6 dop_on_gp4.01750408
131b.l24x2 dop_on_gp4.8450406
132b.b25x3 dop_on_gp4.440405
133b.l25x3 dop_on_gp9.3480509
134b.l26x5 dop_on_gp5.7350405
135b.l27x1 dop_on_gp10.2350609
136b.l27x2 dop_on_gp8.32750409
137b.b28x3 dop_on_gp4.0620507
138b.b28x4 dop_on_gp6.49750406
139b.b28x6 dop_on_gp10.090409
140g.h1x11 dop_on_gp3.370509
141g.l1x4 dop_on_gp6.770608
142g.h2x9 dop_on_gp2.6150404
143g.ctx3 dop_on_gp5.813330609
144g.ctx6 dop_on_gp2.998330606
145g.ctx15 dop_on_gp4.65250409
146g.ctx16 dop_on_gp3.8620508
1472x42 Shared6.237.906457
1482x57 Shared6.4353.462457
149E1x50 Shared6.658335.352658
150E1x52 Shared8.2668.155547
1513x34 Shared6.8755.43455
1523x37 Shared4.035.06447
1533x51 Shared7.75756.76458
1544x50 Shared7.2488.79549
155E2 Shared10.37212.74415103
1565x44 Shared5.73755.8225445
1575x47 Shared5.1946.138558
1585x58 Shared6.7927.3548
1596x44 Shared5.247510.885449
1606x48 Shared5.828339.24667668
1617x42 Shared9.55258.2225447
162Lig Shared11.869.2320110
1631x39 dop_off9.5553.63247
1642x45 dop_off6.143339.61349
1652x50 dop_off1.956.955149
1663x43 dop_off3.374.49348
1673x49 dop_off10.5559.5425248
1685x61 dop_off5.9254.665248
1696x30 dop_off6.322.62246
1706x34 dop_off3.933336.6725347
1717x27 dop_off4.996673.79343
1727x45 dop_off9.425.655349
1737x53 dop_off6.96.9125349
1748x47 dop_off4.723337.5425348
   
Orange: nodes, hubs and links specific of dop_on_gp network

Green: nodes, hubs and links shared by both networks

Purple: nodes, hubs and links specific of dop_off network

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Owner: the name of the network the link belong to or "Shared" if the corresponding link is present in both networks.

Recurrence: the relative Recurrence in the filtered pool of shortest paths.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.


Index Node1 Node2 Owner dop_on_gp Recurrence dop_off Recurrence dop_on_gp Hub1? dop_off Hub1? dop_on_gp Hub2? dop_off Hub2? ConSurf1 ConSurf2
12x60 Lig dop_on_gp51.62230YesNoYesYes50
22x57 2x60 dop_on_gp54.29140YesYesYesNo75
31x43 2x57 dop_on_gp60.43444.59611NoNoYesYes67
41x43 1x47 dop_on_gp61.10170NoNoNoNo66
51x47 2x54 dop_on_gp61.43516.87114NoNoNoNo66
62x54 7x47 dop_on_gp61.76840NoNoNoNo67
71x50 7x47 dop_on_gp62.43440NoNoNoNo97
81x50 7x51 dop_on_gp63.09980NoNoYesNo96
91x53 7x51 dop_on_gp64.32720YesNoYesNo86
101x53 1x57 dop_on_gp67.74020YesNoNoNo87
111x57 2x44 dop_on_gp73.9890NoNoYesNo76
122x44 I1x50 dop_on_gp74.73320YesNoNoNo67
132x41 I1x50 dop_on_gp75.0590YesNoNoNo67
143x49 I2x57 dop_on_gp88.16294.28295NoYesYesNo86
156x52 Lig dop_on_gp12.4390YesNoYesYes70
16G.H5.19 I2x57 dop_on_gp90.6990NoNoYesNo86
17G.H5.15 G.H5.19 dop_on_gp91.35740NoNoNoNo78
18G.H5.11 G.H5.15 dop_on_gp92.28730NoNoNoNo87
19G.H5.11 G.S1.02 dop_on_gp45.97980NoNoYesNo85
20G.H5.11 G.S3.03 dop_on_gp46.62290NoNoYesNo87
21G.S1.02 G.S1.04 dop_on_gp48.15880YesNoYesNo57
22G.S1.04 G.S4.03 dop_on_gp49.25370YesNoYesNo77
23G.S1.04 G.S3.03 dop_on_gp47.98790YesNoYesNo77
24G.S1.04 G.S3.05 dop_on_gp47.04960YesNoYesNo77
25G.S1.06 G.S3.05 dop_on_gp47.31260YesNoYesNo87
26G.H1.01 G.S1.06 dop_on_gp98.02860YesNoYesNo98
27G.H1.01 G.s1h1.01 dop_on_gp98.16620YesNoNoNo99
28G.S4.04 G.s1h1.01 dop_on_gp1000YesNoNoNo99
29G.S1.07 G.S4.04 dop_on_gp94.06420YesNoYesNo99
30G.S1.05 G.S1.07 dop_on_gp51.97120NoNoYesNo99
31G.S1.05 G.h2s4.01 dop_on_gp52.06880NoNoYesNo99
32G.h2s4.01 b.l5x5 dop_on_gp38.06340YesNoYesNo99
33G.S1.06 G.S4.03 dop_on_gp50.95190YesNoYesNo87
34G.S1.07 G.S4.02 dop_on_gp21.91140YesNoYesNo98
35G.H3.12 G.S1.07 dop_on_gp20.25290NoNoYesNo89
36G.H2.07 G.h2s4.01 dop_on_gp28.51410YesNoYesNo99
37G.H2.04 G.H3.12 dop_on_gp20.14020NoNoNoNo98
38G.H2.04 G.H2.07 dop_on_gp20.02180NoNoYesNo99
39G.H2.02 G.H2.07 dop_on_gp47.96210YesNoYesNo89
40G.H2.02 b.l9x6 dop_on_gp27.90730YesNoYesNo88
41G.H2.02 b.l13x6 dop_on_gp27.90730YesNoYesNo89
42G.H3.18 G.S4.02 dop_on_gp21.8150YesNoYesNo98
43G.H3.15 G.H3.18 dop_on_gp21.55070YesNoYesNo89
44G.H2.10 b.l5x5 dop_on_gp10.70910NoNoYesNo79
45G.H2.09 G.H2.10 dop_on_gp10.81180NoNoNoNo87
46G.H3.15 G.H3.17 dop_on_gp21.40030YesNoYesNo85
47G.S4.04 G.S4.06 dop_on_gp11.62070YesNoNoNo97
48G.S4.04 G.S5.04 dop_on_gp13.42670YesNoNoNo99
49G.H4.15 G.S4.06 dop_on_gp11.30370YesNoNoNo87
50G.H4.15 G.S5.04 dop_on_gp11.30170YesNoNoNo89
51G.H3.17 b.l25x6 dop_on_gp19.60980YesNoNoNo58
52G.HG.15 G.hgh4.05 dop_on_gp11.80920YesNoYesNo77
53b.l5x3 b.l5x5 dop_on_gp28.8790NoNoYesNo89
54b.l5x3 b.l7x3 dop_on_gp28.72410NoNoNoNo89
55b.l7x3 b.l7x5 dop_on_gp28.5730NoNoNoNo96
56b.b9x3 b.l7x5 dop_on_gp28.29430NoNoNoNo66
57b.b9x3 b.l8x10 dop_on_gp28.00870NoNoNoNo64
58b.b8x4 b.l8x10 dop_on_gp27.91740YesNoNoNo64
59b.b7x2 b.b8x4 dop_on_gp27.2650NoNoYesNo86
60b.b6x5 b.b7x2 dop_on_gp26.88370YesNoNoNo68
61b.b2x4 b.b6x5 dop_on_gp29.06170NoNoYesNo66
62b.b10x4 b.b2x4 dop_on_gp28.90610NoNoNoNo66
63b.b10x4 b.b14x5 dop_on_gp27.57870NoNoNoNo65
64b.b14x5 b.b15x1 dop_on_gp26.78190NoNoYesNo59
65b.b15x1 b.b16x6 dop_on_gp25.34840YesNoYesNo98
66b.b16x4 b.b16x6 dop_on_gp23.23350YesNoYesNo68
67b.b16x4 b.b17x6 dop_on_gp23.25220YesNoNoNo67
68b.b17x6 g.h1x14 dop_on_gp23.09040NoNoNoNo79
69g.h1x11 g.h1x14 dop_on_gp22.92840YesNoNoNo99
70b.1x15 g.h1x11 dop_on_gp20.15150NoNoYesNo79
71b.1x15 g.l1x4 dop_on_gp11.81820NoNoYesNo78
72b.l23x1 b.l25x6 dop_on_gp24.11040YesNoNoNo68
73b.l21x7 b.l23x1 dop_on_gp18.33770NoNoYesNo56
74b.b23x6 b.l21x7 dop_on_gp17.51790YesNoNoNo75
75b.b23x6 b.b24x6 dop_on_gp14.92720YesNoYesNo78
76b.b21x7 b.b24x6 dop_on_gp14.43370YesNoYesNo58
77b.l11x1 b.l9x6 dop_on_gp25.0750YesNoYesNo98
78b.b11x6 b.l11x1 dop_on_gp46.32610YesNoYesNo99
79b.b11x6 b.l9x3 dop_on_gp39.25330YesNoYesNo99
80b.b12x6 b.l9x3 dop_on_gp34.15080YesNoYesNo89
81b.b11x2 b.b12x6 dop_on_gp29.67260NoNoYesNo78
82b.b10x5 b.b11x2 dop_on_gp14.19290YesNoNoNo97
83b.l11x1 b.l13x6 dop_on_gp25.0750YesNoYesNo99
84b.b7x1 b.b8x3 dop_on_gp16.78860YesNoYesNo46
85b.b11x2 b.l12x1 dop_on_gp14.8380NoNoYesNo76
862x41 4x46 Shared76.688610.6751YesNoNoNo67
872x42 4x46 Shared81.727241.6413YesYesNoNo77
882x42 3x49 Shared87.842616.3028YesYesNoYes78
893x36 Lig dop_off9.5919614.9489NoNoYesYes80
905x40 Lig dop_off1.4301539.9834YesNoYesYes50
915x43 Lig dop_off2.4938439.7439NoNoYesYes50
926x48 Lig dop_off080.1418YesYesYesYes80
931x39 2x57 dop_off022.2806NoYesYesYes77
942x57 7x42 dop_off3.132546.5967YesYesYesYes77
951x36 2x61 dop_off0.36022811.3659YesNoNoNo66
961x39 2x61 dop_off013.5857NoYesNoNo76
972x54 2x57 dop_off013.5857NoNoYesYes67
981x50 2x50 dop_off010.6751NoNoNoYes99
992x50 7x49 dop_off020.899NoYesYesNo99
1007x49 7x53 dop_off0.71359422.8885YesNoNoYes99
1016x36 7x53 dop_off028.728NoNoNoYes89
1026x36 8x47 dop_off038.1137NoNoNoYes88
1036x32 8x47 dop_off058.6166NoNoNoYes78
1046x32 6x33 dop_off063.2127NoNoNoNo78
1053x50 6x33 dop_off064.7508NoNoNoNo98
1063x50 6x34 dop_off067.6983NoNoNoYes97
1075x61 6x34 dop_off083.6603NoYesNoYes87
1085x58 5x61 dop_off0100YesYesNoYes88
1093x47 5x58 dop_off0.36069675.8865NoNoYesYes98
1103x47 5x54 dop_off076.2826NoNoNoNo98
1115x54 6x41 dop_off077.4431NoNoNoNo87
1123x43 6x41 dop_off078.9352NoYesNoNo87
1133x43 6x44 dop_off2.1382187.5748NoYesYesYes89
1146x44 6x48 dop_off2.8471282.4169YesYesYesYes98
1152x45 4x50 dop_off3.1520732.4123NoYesYesYes99
1162x45 4x49 dop_off036.1978NoYesNoNo96
1173x41 4x49 dop_off037.7176NoNoNoNo66
1183x37 3x41 dop_off0.71523137.865YesYesNoNo76
1193x37 5x43 dop_off2.1381338.3347YesYesNoNo75
1201x60 I1x50 dop_off010.6751NoNoNoNo57
1218x50 I1x50 dop_off012.7567YesNoNoNo87
1228x47 8x50 dop_off020.899NoYesYesNo88
1232x45 4x46 dop_off4.8624544.9019NoYesNoNo97
1242x42 3x46 dop_off030.4228YesYesNoNo79
1252x42 4x45 dop_off5.7498412.2133YesYesNoNo75
1262x46 3x43 dop_off015.9805NoNoNoYes98
1272x46 3x42 dop_off1.0966716.4318NoNoNoNo98
1283x28 E1x50 dop_off011.1817NoNoYesYes58
1292x63 E1x50 dop_off0.00077971438.5005NoNoYesYes48
1302x60 2x63 dop_off044.248YesNoNoNo54
1312x60 7x42 dop_off0.023157546.0072YesNoYesYes57
132E1x50 E1x52 dop_off2.1682313.5489YesYesYesYes87
1335x36 E2 dop_off0.3659227.9267NoNoYesYes43
1345x36 5x40 dop_off0.35929229.9991NoNoYesNo45
135E1x50 E2x50 dop_off0.0013255111.2094YesYesYesNo89
1363x34 4x50 dop_off1.0810718.8081YesYesYesYes59
1373x36 6x52 dop_off013.9265NoNoYesNo87
1386x48 6x52 dop_off7.1251834.1255YesYesYesNo87
1395x58 6x37 dop_off0.36077431.0859YesYesNoNo87
1403x51 5x61 dop_off022.8885YesYesNoYes88
1414x41 I2x56 dop_off012.3238NoNoNoNo43
1425x35 E2 dop_off0.36085111.3659NoNoYesYes43
1435x47 6x52 dop_off2.4996845.3809YesYesYesNo87
1445x44 5x47 dop_off0.0024171117.3989YesYesYesYes58
1455x44 5x48 dop_off1.0745211.7804YesYesNoNo54
1466x30 6x34 dop_off0.46798420.7055NoYesNoYes67
1475x65 6x30 dop_off012.4528NoNoNoYes86
1485x65 5x66 dop_off010.6751NoNoNoNo84
1496x58 Lig dop_off3.223115.3818NoNoYesYes40
1506x58 E3 dop_off1.4380313.3831NoNoYesNo42
1517x42 Lig dop_off084.8116YesYesYesYes70
1522x45 3x42 dop_off1.4734314.8015NoYesNoNo98
1533x46 6x37 dop_off029.8425NoNoNoNo97

Here, those paths that begin and end at given residue pair(s) or that pass through a residue are used to generate a novel metapath. Such a path filtering is particularly recommended if some information on allosteric residues is available. The selection syntax for a residue pair ("Pairs") is C:C:c534,A:A:?600 (the lower-case "c" stands for cytosine and "?" indicates any non standard amino acid or nucleotide residue). Selection of more than one apical residue pair has the following syntax: C:C:c534,A:A:?600,C:C:c534,A:A:E41. Only one residue can be selected as a tail ("Tail"). For midway residue(s), each residue must be separated by a comma as well e.g. A:A:?600,A:A:E41.

Midway



Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.


2D representation of the interactions of this orthosteric/allosteric ligand.


Node1Node2OwnerNet1LinkStrengthNet2LinkStrengthComm1Comm2Node1ShellNode2Shell
3x32Ligdop_off16.8101010
3x33LigShared12.113.680210
3x36LigShared13.628.381210
5x40LigShared5.8212.160210
5x43LigShared4.15.050210
6x48Ligdop_off7.0601210
6x51Ligdop_off4.9101010
6x55LigShared17.434.040210
7x38LigShared6.8810.251210
7x42Ligdop_off8.8801210
1x351x39dop_off4.8400222
2x563x28dop_off9.5200221
2x577x42Shared4.6915.240221
2x59E1x52Shared10.729.650222
2x602x63dop_off8.1400211
2x607x42Shared11.2711.270211
2x63E1x50Shared4.644.640211
2x647x35Shared11.988.710221
E1x49E2Shared6.534.852021
E1x50E1x52Shared9.0217.040212
E1x50E2x50Shared7.846.530211
3x22E2Shared16.998.490221
3x25E2x50Shared7.287.280221
3x327x42Shared8.059.21011
3x334x60Shared9.6712.090212
3x366x48Shared8.145.821211
3x366x52dop_off6.5701211
3x375x43Shared5.242.620021
3x406x44Shared8.792.510222
E2E2Shared36.4533.942211
E2E2x51Shared5.925.242212
5x35E2Shared4.019.772021
5x36E2Shared9.5514.332221
5x39E2Shared6.499.080021
5x365x40Shared9.688.32221
5x406x59Shared4.59.010212
5x445x47Shared4.299.651222
5x476x52Shared13.583.391221
6x446x48Shared25.0511.021221
6x447x45dop_off4.8301222
6x486x52Shared4.234.231211
6x487x41dop_off4.2201212
6x487x45Shared6.787.911212
6x517x38dop_off4.4201011
6x547x34Shared8.539.740021
6x58E3Shared20.0450212
7x31E3dop_off13.0800022
6x58LigShared3.926.130210
4x63E2Shared3.733.730221
2x632x64dop_off3.5800212
1x392x57dop_off3.5200022
3x33E2x52dop_off3.5200211
3x29E2x50Shared3.173.170211
3x294x64dop_off3.1500212
7x347x38Shared2.854.280211
3x21E1x50Shared2.812.810021
3x28E1x50dop_off2.4500211
5x32E2Shared1.322.640021
1x352x64dop_on_gp012.090222
1x357x35dop_on_gp02.650221
1x397x35dop_on_gp013.070021
1x397x38dop_on_gp06.040021
2x562x60dop_on_gp05.670221
2x567x42dop_on_gp02.50221
2x572x60dop_on_gp02.660221
2x593x28dop_on_gp03.930221
2x60Ligdop_on_gp010.540210
2x63Ligdop_on_gp015.20210
3x25E1x50dop_on_gp03.920221
E1x50Ligdop_on_gp05.010210
3x25E2dop_on_gp03.380221
3x28Ligdop_on_gp02.620210
3x29E2x52dop_on_gp02.770211
3x29Ligdop_on_gp04.870210
3x363x37dop_on_gp03.731212
3x406x48dop_on_gp03.520221
4x60E2x52dop_on_gp04.280021
E2E3dop_on_gp011.732212
E2Ligdop_on_gp03.682210
E2x50Ligdop_on_gp05.590210
E2E2x52dop_on_gp03.652211
E2x52Ligdop_on_gp05.30210
5x31E2dop_on_gp07.130221
5x366x59dop_on_gp02.892222
5x406x55dop_on_gp04.550211
5x446x52dop_on_gp05.661221
6x487x46dop_on_gp02.471212
6x516x55dop_on_gp03.071011
6x517x37dop_on_gp03.271012
6x52Ligdop_on_gp03.271210
6x547x30dop_on_gp02.620022
6x587x30dop_on_gp02.450212
E3E3dop_on_gp016.670222
7x317x35dop_on_gp02.770021
7x34Ligdop_on_gp05.960210
7x35Ligdop_on_gp02.770210

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Difference Members
Id Description
dop_on_gp 8F7S-δ-Deltorphin-Gi1/β1/γ2
dop_off 4EJ4-δ-Naltrindole
Network Difference
Value dop_on_gp dop_off
Imin 2.44 4
Number of Linked Nodes 812 241
Number of Specific Nodes 586 (72.17%) 15  (6.22%)
Number of Shared Nodes 226 (27.83%) 226  (93.78%)
Number of Links 1018 250
Number of Specific Links 890 (87.43%) 122  (48.80%)
Number of Shared Links 128 (12.57%) 128  (51.20%)
Number of Hubs 162 28
Number of Specific Hubs 146 (90.12%) 12  (42.86%)
Number of Shared Hubs 16 (9.88%) 16  (57.14%)
Average % Shared Neighbours (Jaccard) 10.66
Average % Shared Neighbours (Otsuka) 13.30
Average % Shared Neighbours (Overlap Coefficient) 16.12
Average % Shared Cliques (k3-6) 50.00
Graphlets Similarity 0.498449
Paths Difference
Value dop_on_gp dop_off
Number Of Nodes in MetaPath 86 67
Specific Nodes in MetaPath 75 (87.21%) 56  (83.58%)
Shared Nodes in MetaPath 226 (27.83%) 226  (27.83%)
Number Of Links MetaPath 88 68
Specific Links in MetaPath 85 (96.59%) 65  (95.59%)
Shared Links in MetaPath 128 (12.57%) 128  (12.57%)
Number of Shortest Paths 1911482 28708
Length Of Smallest Path 3 3
Average Path Length 32.4273 12.4765
Length of Longest Path 65 30
Minimum Path Strength 1.295 1.295
Average Path Strength 5.51013 7.21262
Maximum Path Strength 21.12 17.12
Minimum Path Correlation 0.7 0.7
Average Path Correlation 0.984092 0.922362
Maximum Path Correlation 1 0.99
Minimum % Of Corr. Nodes 2.12766 4.7619
Average % Of Corr. Nodes 40.7425 51.5426
Maximum % Of Corr. Nodes 100 100
Minimum Path Hubs % 0 0
Average Path Hubs % 53.9093 43.3544
Maximum Path Hubs % 100 100

Details about the values in these tables can be found in the corresponding documentation page .

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