Orange: nodes, hubs and links specific of etb_on_gp network

Green: nodes, hubs and links shared by both networks

Purple: nodes, hubs and links specific of etb_off network

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Owner: the name of the network the hub belong to or "Shared" if the corresponding hub is present in both networks.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub in the corresponding network.

Num Of Links: the number of links of the corresponding hub in the corresponding network.

ConSurf: this column reports the ConSurf conservation grades of each hub.


Index Hub Owner etb_on_gp Avg Int. Strength etb_off Avg Int. Strength etb_on_gp Num Of Links etb_off Num Of Links ConSurf
1G.S1.05 etb_on_gp1000409
2G.S1.06 etb_on_gp500408
3G.S1.07 etb_on_gp1000409
4G.H1.01 etb_on_gp00409
5G.S2.03 etb_on_gp500509
6G.S2.08 etb_on_gp1000505
7G.S3.03 etb_on_gp1000707
8G.S3.04 etb_on_gp500406
9G.S3.06 etb_on_gp1000505
10G.S3.07 etb_on_gp500409
11G.H2.06 etb_on_gp1000709
12G.H2.07 etb_on_gp1000509
13G.H2.09 etb_on_gp1000408
14G.h2s4.01 etb_on_gp1000509
15G.h2s4.02 etb_on_gp00407
16G.S4.02 etb_on_gp1000508
17G.S4.03 etb_on_gp500407
18G.S4.04 etb_on_gp1000609
19G.s4h3.01 etb_on_gp00407
20G.s4h3.03 etb_on_gp500408
21G.H3.17 etb_on_gp500505
22G.H3.18 etb_on_gp500509
23G.S5.02 etb_on_gp1000406
24G.S5.04 etb_on_gp1000509
25G.S5.05 etb_on_gp1000709
26G.S5.07 etb_on_gp00409
27G.HG.05 etb_on_gp500405
28G.HG.07 etb_on_gp1000409
29G.HG.08 etb_on_gp500506
30G.hgh4.02 etb_on_gp1000607
31G.H4.10 etb_on_gp500406
32G.H4.15 etb_on_gp500408
33G.H4.16 etb_on_gp500403
34G.h4s6.11 etb_on_gp500407
35G.h4s6.12 etb_on_gp1000404
36G.S6.01 etb_on_gp1000405
37G.S6.02 etb_on_gp1000507
38G.H5.08 etb_on_gp1000608
39G.H5.13 etb_on_gp00508
40G.H5.17 etb_on_gp1000505
41G.H5.26 etb_on_gp500405
42b.lhb1x6 etb_on_gp500503
43b.b1x3 etb_on_gp500407
44b.l1x3 etb_on_gp1000509
45b.l1x6 etb_on_gp1000409
46b.b2x1 etb_on_gp1000608
47b.b2x3 etb_on_gp1000406
48b.b2x5 etb_on_gp1000607
49b.l3x1 etb_on_gp00409
50b.l3x2 etb_on_gp500409
51b.b4x3 etb_on_gp1000507
52b.b4x4 etb_on_gp1000408
53b.b4x5 etb_on_gp1000407
54b.b4x6 etb_on_gp1000509
55b.b5x2 etb_on_gp500507
56b.b5x3 etb_on_gp1000609
57b.b5x5 etb_on_gp00405
58b.b5x7 etb_on_gp1000407
59b.l5x1 etb_on_gp1000408
60b.l5x5 etb_on_gp1000709
61b.b6x3 etb_on_gp00408
62b.b6x5 etb_on_gp1000406
63b.b7x1 etb_on_gp500404
64b.b7x4 etb_on_gp1000408
65b.b8x3 etb_on_gp1000406
66b.b8x4 etb_on_gp1000506
67b.l8x3 etb_on_gp00403
68b.l8x5 etb_on_gp00403
69b.l9x3 etb_on_gp1000509
70b.l9x6 etb_on_gp1000808
71b.b10x3 etb_on_gp1000408
72b.b10x5 etb_on_gp1000509
73b.l10x1 etb_on_gp1000403
74b.b11x4 etb_on_gp1000409
75b.l11x2 etb_on_gp1000509
76b.b12x5 etb_on_gp500406
77b.b12x6 etb_on_gp1000608
78b.b12x7 etb_on_gp00409
79b.b13x7 etb_on_gp1000507
80b.l13x3 etb_on_gp1000609
81b.l13x6 etb_on_gp1000409
82b.l13x7 etb_on_gp1000509
83b.b14x1 etb_on_gp500408
84b.b14x3 etb_on_gp500505
85b.b15x1 etb_on_gp1000409
86b.b15x2 etb_on_gp1000406
87b.b15x3 etb_on_gp500409
88b.l15x1 etb_on_gp1000607
89b.l15x2 etb_on_gp1000509
90b.b16x4 etb_on_gp1000506
91b.b16x5 etb_on_gp500405
92b.b16x6 etb_on_gp1000608
93b.l16x3 etb_on_gp500403
94b.b17x7 etb_on_gp500408
95b.l17x3 etb_on_gp1000609
96b.l17x6 etb_on_gp1000509
97b.b18x3 etb_on_gp1000408
98b.b18x5 etb_on_gp1000505
99b.l18x1 etb_on_gp1000606
100b.l18x2 etb_on_gp1000407
101b.l18x3 etb_on_gp1000405
102b.b19x2 etb_on_gp1000606
103b.b19x4 etb_on_gp1000408
104b.l19x2 etb_on_gp00409
105b.b20x2 etb_on_gp500406
106b.b20x4 etb_on_gp1000508
107b.b20x5 etb_on_gp00407
108b.b20x6 etb_on_gp1000606
109b.b21x1 etb_on_gp500407
110b.b21x2 etb_on_gp500406
111b.b21x7 etb_on_gp1000605
112b.l21x5 etb_on_gp1000504
113b.l21x7 etb_on_gp500405
114b.b22x5 etb_on_gp1000807
115b.l22x5 etb_on_gp1000509
116b.b23x2 etb_on_gp1000406
117b.b23x6 etb_on_gp1000707
118b.b24x2 etb_on_gp500505
119b.b24x3 etb_on_gp500405
120b.b24x4 etb_on_gp1000606
121b.b24x5 etb_on_gp1000405
122b.b24x6 etb_on_gp1000408
123b.b24x7 etb_on_gp500409
124b.l24x2 etb_on_gp500406
125b.l24x3 etb_on_gp00405
126b.b25x3 etb_on_gp1000405
127b.b25x7 etb_on_gp500407
128b.l25x3 etb_on_gp1000509
129b.b26x3 etb_on_gp1000606
130b.l26x1 etb_on_gp00407
131b.l26x5 etb_on_gp1000605
132b.l27x1 etb_on_gp1000809
133b.l27x2 etb_on_gp500509
134b.b28x4 etb_on_gp1000406
135b.b28x5 etb_on_gp00405
136b.b28x6 etb_on_gp1000609
137g.h2x11 etb_on_gp1000406
138g.ctx3 etb_on_gp1000609
139g.ctx6 etb_on_gp500406
140g.ctx14 etb_on_gp1000709
141g.ctx15 etb_on_gp500409
142g.ctx16 etb_on_gp1000908
143NT.C90 etb_on_gp00417
1441x27 etb_on_gp500535
1451x43 etb_on_gp10033.3333437
1462x39 etb_on_gp500538
1472x50 etb_on_gp10033.3333439
1482x54 etb_on_gp00416
1492x56 etb_on_gp5033.3333426
1502x60 etb_on_gp500427
1512x64 etb_on_gp00434
1523x31 etb_on_gp033.3333435
1533x51 etb_on_gp500428
154I2x52 etb_on_gp00425
1554x56 etb_on_gp5033.3333435
156E2.Q261 etb_on_gp00532
1575x39 etb_on_gp10033.3333437
1585x40 etb_on_gp00415
1595x43 etb_on_gp10033.3333536
1605x461 etb_on_gp1000536
1615x50 etb_on_gp500419
1626x29 etb_on_gp500415
1636x30 etb_on_gp00437
164E3.D354 etb_on_gp500421
165Lig Shared10010032150
1661x32 Shared00446
1671x50 Shared00449
168I1x50 Shared033.3333447
1692x46 Shared10033.3333449
1702x53 Shared50100468
1712x57 Shared10033.3333547
172E1x50 Shared100100479
173E1x52 Shared0100457
1743x30 Shared5033.3333446
1753x33 Shared10066.6667544
1763x50 Shared10066.6667549
1774x41 Shared00445
1784x61 Shared100100555
179E2.H258 Shared00544
1805x32 Shared033.3333454
1815x35 Shared5066.6667453
1825x42 Shared500444
1835x44 Shared066.6667456
1845x46 Shared100100445
1855x47 Shared5066.6667448
1865x57 Shared033.3333457
1875x58 Shared00449
1885x65 Shared5033.3333548
1896x26 Shared1000644
1906x48 Shared100100868
1916x52 Shared5066.6667448
1927x23 Shared033.3333445
1937x35 Shared50100543
1947x49 Shared00449
1958x50 Shared100100469
1968x54 Shared500447
197NT.P88 etb_off00147
1981x31 etb_off033.3333344
1991x35 etb_off5066.6667345
2001x36 etb_off00246
2011x53 etb_off10066.6667369
2022x40 etb_off00248
2033x29 etb_off5033.3333345
204I2x54 etb_off00144
2054x65 etb_off066.6667345
2065x64 etb_off00145
2076x44 etb_off50100349
2086x62 etb_off033.3333352
2097x45 etb_off5033.3333349
2107x54 etb_off00347
   
Orange: nodes, hubs and links specific of etb_on_gp network

Green: nodes, hubs and links shared by both networks

Purple: nodes, hubs and links specific of etb_off network

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Owner: the name of the network the link belong to or "Shared" if the corresponding link is present in both networks.

Recurrence: the relative Recurrence in the filtered pool of shortest paths.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.


Index Node1 Node2 Owner etb_on_gp Recurrence etb_off Recurrence etb_on_gp Hub1? etb_off Hub1? etb_on_gp Hub2? etb_off Hub2? ConSurf1 ConSurf2
1b.l2x3 b.l2x5 etb_on_gp23.86290NoNoNoNo85
2b.b3x1 b.l2x3 etb_on_gp23.58890NoNoNoNo58
3b.b3x1 b.b5x4 etb_on_gp11.23780NoNoNoNo55
4G.S1.05 G.h2s4.01 etb_on_gp29.56420YesNoYesNo99
5G.S1.05 G.S1.07 etb_on_gp64.5120YesNoYesNo99
6G.S1.07 G.S4.04 etb_on_gp99.71550YesNoYesNo99
7G.S4.04 G.s1h1.01 etb_on_gp1000YesNoNoNo99
8G.H1.01 G.s1h1.01 etb_on_gp99.84420YesNoNoNo99
9G.H1.01 G.S1.06 etb_on_gp98.54990YesNoYesNo98
10G.S1.06 G.S4.03 etb_on_gp97.32690YesNoYesNo87
11G.H3.18 G.S1.05 etb_on_gp35.40750YesNoYesNo99
12G.H3.15 G.H3.18 etb_on_gp29.19380NoNoYesNo89
13G.H3.15 G.H3.17 etb_on_gp29.27690NoNoYesNo85
14G.H3.17 b.l27x1 etb_on_gp28.78710YesNoYesNo59
15b.b26x1 b.l27x1 etb_on_gp15.52210NoNoYesNo99
16b.b26x1 b.b26x2 etb_on_gp15.40420NoNoNoNo97
17b.b26x2 b.b2x3 etb_on_gp15.29410NoNoYesNo76
18G.S4.03 G.S5.05 etb_on_gp93.14990YesNoYesNo79
19b.l2x5 b.l4x2 etb_on_gp21.50760NoNoNoNo54
20b.l26x5 g.ctx4 etb_on_gp14.27860YesNoNoNo57
21g.ctx3 g.ctx4 etb_on_gp16.82140YesNoNoNo97
22b.l22x2 g.ctx3 etb_on_gp15.75870NoNoYesNo19
23b.l22x2 g.ctx2 etb_on_gp15.70640NoNoNoNo13
24g.ctx2 g.h2x15 etb_on_gp15.65840NoNoNoNo36
25g.h2x11 g.h2x15 etb_on_gp16.52530YesNoNoNo66
26b.l18x1 g.h2x11 etb_on_gp11.0110YesNoYesNo66
27b.b20x5 b.b22x5 etb_on_gp12.28540YesNoYesNo77
28b.b20x5 b.b21x4 etb_on_gp18.40110YesNoNoNo75
29b.b21x4 g.h2x1 etb_on_gp17.50280NoNoNoNo58
30b.b21x2 g.h2x1 etb_on_gp17.35540YesNoNoNo68
31b.1x18 b.b21x2 etb_on_gp17.69670NoNoYesNo46
32b.1x14 b.1x18 etb_on_gp61.21150NoNoNoNo44
33b.1x14 b.1x15 etb_on_gp60.53460NoNoNoNo47
34b.1x12 b.1x15 etb_on_gp60.19590NoNoNoNo67
35b.1x12 g.h1x11 etb_on_gp58.83950NoNoNoNo69
36g.h1x11 g.h1x14 etb_on_gp51.72020NoNoNoNo99
37b.b17x6 g.h1x14 etb_on_gp51.37740NoNoNoNo79
38b.b16x4 b.b17x6 etb_on_gp51.03440YesNoNoNo67
39b.b16x4 b.l13x3 etb_on_gp13.15290YesNoYesNo69
40b.b14x3 b.b15x3 etb_on_gp17.76830YesNoYesNo59
41b.b10x2 b.b14x3 etb_on_gp25.6840NoNoYesNo65
42b.b10x2 b.b6x2 etb_on_gp24.61570NoNoNoNo68
43b.b10x3 b.b6x2 etb_on_gp23.54720YesNoNoNo88
44b.b10x3 b.b11x4 etb_on_gp19.26830YesNoYesNo89
45b.b11x4 b.l9x3 etb_on_gp12.84850YesNoYesNo99
46b.l4x2 g.ctx16 etb_on_gp15.31350NoNoYesNo48
47b.b16x4 b.b16x6 etb_on_gp36.54330YesNoYesNo68
48G.H2.07 G.h2s4.01 etb_on_gp23.03250YesNoYesNo99
49G.H2.06 b.l9x6 etb_on_gp24.90210YesNoYesNo98
50G.H2.05 G.H2.08 etb_on_gp44.9040NoNoNoNo88
51G.H2.05 G.H2.06 etb_on_gp44.45680NoNoYesNo89
52G.H2.06 b.l17x6 etb_on_gp68.45870YesNoYesNo99
53G.S5.03 G.S5.05 etb_on_gp85.03420NoNoYesNo89
54G.H5.10 G.S5.03 etb_on_gp84.69540NoNoNoNo68
55G.H5.10 G.S6.02 etb_on_gp84.5260NoNoYesNo67
56G.H5.13 G.S6.02 etb_on_gp76.53060YesNoYesNo87
576x30 G.H5.13 etb_on_gp74.04760YesNoYesNo78
583x50 G.H5.23 etb_on_gp67.92870YesYesNoNo94
593x50 5x61 etb_on_gp73.49390YesYesNoNo98
605x61 5x65 etb_on_gp73.64211.29435NoNoYesYes88
612x39 G.H5.23 etb_on_gp66.82630YesNoNoNo84
622x39 I1x52 etb_on_gp63.74410YesNoNoNo88
631x56 8x54 etb_on_gp62.26514.37596NoNoYesYes77
641x56 8x53 etb_on_gp62.45351.46367NoNoNoNo74
658x53 I1x50 etb_on_gp62.64180NoNoYesYes47
662x40 I1x50 etb_on_gp63.39331.06107NoYesYesYes87
67b.l17x5 b.l17x6 etb_on_gp68.19650NoNoYesNo69
68b.l17x5 b.l19x2 etb_on_gp68.21810NoNoYesNo69
69b.b19x6 b.l19x2 etb_on_gp35.30890NoNoYesNo99
70b.b19x6 b.l17x3 etb_on_gp35.18750NoNoYesNo99
71b.b20x6 b.l17x3 etb_on_gp31.93480YesNoYesNo69
72b.b17x7 b.b20x6 etb_on_gp53.89080YesNoYesNo86
73b.b17x7 b.b21x1 etb_on_gp51.6840YesNoYesNo87
74b.b20x2 b.l19x2 etb_on_gp32.70640YesNoYesNo69
75b.b20x2 b.b20x4 etb_on_gp32.45960YesNoYesNo68
76b.b20x4 b.b20x6 etb_on_gp31.91040YesNoYesNo86
77b.1x18 b.b21x1 etb_on_gp51.90530NoNoYesNo47
78b.b13x7 b.b16x6 etb_on_gp17.07640YesNoYesNo78
79b.b13x5 b.b13x7 etb_on_gp16.53610NoNoYesNo47
80b.l4x1 g.ctx16 etb_on_gp11.05420NoNoYesNo58
81b.b3x1 b.b6x5 etb_on_gp12.08050NoNoYesNo56
82b.b3x3 b.b6x5 etb_on_gp11.24830NoNoYesNo86
83b.b3x3 b.b4x3 etb_on_gp10.9750NoNoYesNo87
84b.b13x4 b.b13x5 etb_on_gp10.43790NoNoNoNo44
85b.b12x7 b.b13x4 etb_on_gp10.11580YesNoNoNo94
86b.l25x6 b.l27x1 etb_on_gp13.28840NoNoYesNo89
87b.l23x1 b.l25x6 etb_on_gp13.09920NoNoNoNo68
88b.l21x7 b.l23x1 etb_on_gp13.01090YesNoNoNo56
89b.b23x6 b.l21x7 etb_on_gp12.26340YesNoYesNo75
90b.b23x6 b.b24x6 etb_on_gp10.93330YesNoYesNo78
91b.b21x7 b.b24x6 etb_on_gp11.15670YesNoYesNo58
927x49 7x53 etb_on_gp58.47130YesYesNoNo99
932x46 2x50 etb_on_gp27.00719.76032YesYesYesNo99
942x50 7x46 etb_on_gp26.71860YesNoNoNo99
952x54 7x46 etb_on_gp26.51731.49377YesNoNoNo69
962x54 2x57 etb_on_gp23.9380YesNoYesYes67
971x39 2x57 etb_on_gp23.68342.98378NoNoYesYes77
981x39 7x39 etb_on_gp22.47120NoNoNoNo75
991x35 7x39 etb_on_gp21.86492.87843NoYesNoNo55
1007x35 Lig etb_on_gp19.95330YesYesYesYes30
1013x37 5x461 etb_on_gp12.19880NoNoYesNo66
1023x37 4x53 etb_on_gp12.391.4712NoNoNoNo68
1034x46 4x50 etb_on_gp13.36380NoNoNoNo79
1042x45 4x46 etb_on_gp27.33048.73312NoNoNoNo97
1052x45 3x42 etb_on_gp27.51690NoNoNoNo98
1064x51 4x52 etb_on_gp13.38450NoNoNoNo44
1074x47 4x51 etb_on_gp13.58460.00376265NoNoNoNo34
1084x46 4x47 etb_on_gp13.78560NoNoNoNo73
109E2.Q261 E2x52 etb_on_gp11.92410YesNoNoNo25
1105x39 E2x52 etb_on_gp12.57470YesNoNoNo75
111b.b2x5 b.l4x1 etb_on_gp11.4130YesNoNoNo75
112b.b2x3 b.b2x5 etb_on_gp14.58330YesNoYesNo67
113G.H3.18 G.S4.02 etb_on_gp38.29050YesNoYesNo98
114G.S1.07 G.S4.02 etb_on_gp35.54270YesNoYesNo98
115G.H2.07 b.l9x6 etb_on_gp23.20530YesNoYesNo98
116G.H2.08 G.H3.18 etb_on_gp44.8070NoNoYesNo89
1175x65 6x30 Shared74.382315.1033YesYesYesNo87
1188x50 8x54 Shared60.190119.8555YesYesYesYes97
1192x40 I1x52 Shared63.580839.6734NoYesNoNo88
1207x53 8x50 Shared58.553668.1943NoNoYesYes99
1212x46 7x49 Shared55.030537.7055YesYesYesYes99
1221x35 7x35 Shared20.57731.5574NoYesYesYes53
1233x38 4x53 Shared12.582221.3305NoNoNoNo78
1243x38 4x50 Shared12.971218.5837NoNoNoNo79
1252x46 3x42 Shared27.705128.0656YesYesNoNo98
1264x56 5x42 Shared10.844420.4086YesNoYesYes54
1274x52 4x56 Shared12.986734.733NoNoYesNo45
1282x53 Lig etb_off028.6789YesYesYesYes80
1292x60 Lig etb_off0.45510152.8201YesNoYesYes70
1302x63 Lig etb_off0.23041349.1816NoNoYesYes50
1313x29 Lig etb_off013.6998NoYesYesYes50
1323x33 Lig etb_off0.19360111.9577YesYesYesYes40
1333x36 Lig etb_off027.4034NoNoYesYes70
1344x65 Lig etb_off013.9256NoYesYesYes50
1355x43 Lig etb_off0.53532411.9916YesNoYesYes60
1366x48 Lig etb_off3.123378.8915YesYesYesYes80
1376x52 Lig etb_off3.1924716.9282YesYesYesYes80
1382x60 2x64 etb_off051.823YesNoYesNo74
1391x35 2x64 etb_off1.0856841.5096NoYesYesNo54
1407x31 7x35 etb_off0.21721529.4729NoNoYesYes33
1417x27 7x31 etb_off025.9585NoNoNoNo33
1426x62 7x27 etb_off0.00087458317.5942NoYesNoNo23
1436x62 7x23 etb_off0.0018286718.6439NoYesYesYes25
1441x36 2x64 etb_off011.3369NoYesYesNo64
1452x53 2x57 etb_off010.2307YesYesYesYes87
1461x50 2x50 etb_off0.14422710.3322YesYesYesNo99
1477x45 7x49 etb_off0100NoYesYesYes99
1486x48 7x45 etb_off4.443698.7583YesYesNoYes89
1496x40 7x53 etb_off077.4316NoNoNoNo89
1506x40 7x49 etb_off1.4086478.1202NoNoYesYes89
1513x41 4x53 etb_off024.0471NoNoNoNo68
1523x41 4x49 etb_off0.44389125.3941NoNoNoNo67
1533x42 4x49 etb_off026.7336NoNoNoNo87
1542x40 8x50 etb_off050.8711NoYesYesYes89
155I1x52 I2x54 etb_off036.1628NoNoNoYes84
1562x39 3x50 etb_off012.8871YesNoYesYes89
1572x40 3x50 etb_off017.6769NoYesYesYes89
1582x45 4x50 etb_off010.1629NoNoNoNo99
1592x53 2x56 etb_off0.23200313.1128YesYesYesNo86
1602x56 3x31 etb_off011.683YesNoYesNo65
1612x63 E1x50 etb_off0.00015901548.1619NoNoYesYes59
162E1x50 E2.I242 etb_off033.9918YesYesNoNo95
163E2.I242 E2.R253 etb_off0.46472232.927NoNoNoNo55
164E1x49 E2.R253 etb_off1.1607325.4844NoNoNoNo55
165E1x49 E2.L252 etb_off024.1713NoNoNoNo53
166E2.I254 E2.L252 etb_off021.5224NoNoNoNo43
167E2.I254 E2x51 etb_off011.3745NoNoNoNo44
1683x29 4x61 etb_off0.89263112.1383NoYesYesYes55
1693x33 4x61 etb_off0.98144112.2625YesYesYesYes45
1704x61 4x65 etb_off0.45231911.382YesYesNoYes55
1713x36 5x461 etb_off5.8807838.5107NoNoYesNo76
1725x42 5x461 etb_off020.3108YesYesYesNo46
1734x48 4x52 etb_off0.23470633.5629NoNoNoNo34
1744x44 4x48 etb_off032.5507NoNoNoNo33
1754x41 4x44 etb_off1.3313531.5837YesYesNoNo53
1763x52 4x41 etb_off021.5675NoNoYesYes55
1773x48 3x52 etb_off022.7189NoNoNoNo65
1783x48 5x57 etb_off0.23693320.6908NoNoYesYes67
1795x46 5x461 etb_off0.093341917.3571YesYesYesNo56
1804x56 5x46 etb_off1.7462215.9574YesNoYesYes55
1812x39 3x49 etb_off2.206111.1901YesNoNoNo88
1825x64 I2x54 etb_off034.3342NoYesNoYes54
1835x64 5x68 etb_off031.2639NoYesNoNo55
1845x68 6x30 etb_off0.46575521.9475NoNoYesNo57
1854x61 5x35 etb_off0.91775632.799YesYesYesYes53
1865x39 5x43 etb_off8.9519111.0998YesNoYesNo76
1875x35 5x39 etb_off4.3734710.2457YesYesYesNo37
1885x32 5x35 etb_off036.7724YesYesYesYes43
1895x32 E2.Q261 etb_off3.3173716.4165YesYesYesNo42
1905x44 6x52 etb_off0.69616813.2709YesYesYesYes68
1915x47 6x52 etb_off2.3207523.1554YesYesYesYes88
1925x47 6x49 etb_off1.6278420.1189YesYesNoNo85
1935x65 6x34 etb_off011.4309YesYesNoNo87
1945x58 6x34 etb_off010.1893YesYesNoNo97
1958x47 8x50 etb_off0.47012814.1701NoNoYesYes89
1966x49 6x53 etb_off1.3957614.6405NoNoNoNo56
1976x53 6x57 etb_off1.1635113.2822NoNoNoNo65
1987x23 E3.D354 etb_off013.3236YesYesYesNo51
199E3.D354 E3.P355 etb_off1.1603311.4422YesNoNoNo11
2006x57 7x30 etb_off0.46583511.9427NoNoNoNo53
2017x54 8x54 etb_off0.939711.525NoYesYesYes77
2023x36 6x48 etb_off2.819112.0066NoNoYesYes78
2036x48 6x52 etb_off0.050010320.8413YesYesYesYes88

Here, those paths that begin and end at given residue pair(s) or that pass through a residue are used to generate a novel metapath. Such a path filtering is particularly recommended if some information on allosteric residues is available. The selection syntax for a residue pair ("Pairs") is C:C:c534,A:A:?600 (the lower-case "c" stands for cytosine and "?" indicates any non standard amino acid or nucleotide residue). Selection of more than one apical residue pair has the following syntax: C:C:c534,A:A:?600,C:C:c534,A:A:E41. Only one residue can be selected as a tail ("Tail"). For midway residue(s), each residue must be separated by a comma as well e.g. A:A:?600,A:A:E41.

Midway



Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.


2D representation of the interactions of this orthosteric/allosteric ligand.


Node1Node2OwnerNet1LinkStrengthNet2LinkStrengthComm1Comm2Node1ShellNode2Shell
2x53Ligetb_off11.4301210
2x60LigShared5.926.3750210
2x63LigShared5.053334.360210
3x29Ligetb_off4.9466701210
3x32LigShared20.86339.8551210
3x33LigShared14.279.281210
3x36Ligetb_off4.6833301210
4x65Ligetb_off4.3101210
5x43LigShared9.396676.261210
6x48LigShared13.24.6851210
6x51LigShared5.7833321.361210
6x52LigShared4.936675.291210
6x55LigShared9.9233322.711210
7x38LigShared8.032.9450210
7x24NT.C90Shared4.853337.280222
1x247x27etb_off4.3766700021
1x277x31Shared3.806674.9950211
1x277x32etb_off4.6066700212
1x287x35etb_off5.5733300021
1x311x35etb_off5.6404022
1x317x32Shared3.933.9354022
1x317x35etb_off18.226704021
1x32E1.E165etb_off3.600221
1x352x64Shared3.663.434222
1x357x35Shared5.036675.234221
1x427x42Shared5.383335.6550021
2x532x56Shared8.6733310.7151212
2x532x57etb_off3.5333301212
2x533x32etb_off5.7701211
2x533x35Shared5.113.4851212
2x537x46etb_off5.1133301212
2x547x46Shared5.163.09501422
2x59E1x52etb_off12.1400212
2x593x28etb_off5.6333300212
2x63E1x50Shared6.967.540211
E1x49E2.R253Shared14.695.9550212
E1x50E1x51etb_off3.602212
E1x50E1x52etb_off13.363302212
3x25E1x50Shared8.273337.8352221
E1x50E2.I242etb_off4.3066702212
E1x50E2x50Shared8.7066710.452212
E1x51E1x52Shared9.632.892222
3x25E2x50Shared7.287.282222
3x283x29Shared3.534.4150021
3x294x61Shared5.763336.2851212
3x294x65Shared15.419.391211
3x323x33Shared8.136677.461211
3x334x61Shared11.712.151212
3x335x43Shared4.72.821211
3x365x461Shared4.206676.311212
3x366x48Shared6.955.521211
4x614x65Shared7.773338.7451221
4x615x39Shared8.5510.81222
4x65E2x52Shared7.713336.71212
E2.I242E2x50etb_off5.4566702022
E2.I243E2x51etb_off3.8066700021
E2.D246E2.Y251etb_off6.1300212
E2.K248E2.Y247Shared10.746711.940021
5x395x43Shared5.649.1651221
5x425x461etb_off4.1801222
5x445x47Shared6.078.5751222
5x446x52Shared8.296678.4851221
5x476x52Shared17.34679.6151221
6x446x48Shared14.69675.011221
6x447x45Shared6.049.671222
6x486x52Shared6.346674.2351211
6x487x41Shared8.646679.0751212
6x487x45Shared6.786.2151212
6x516x55etb_off4.0501211
6x517x37etb_off3.9901212
6x547x34Shared4.1166710.310021
6x557x34etb_off9.1301211
6x62E3.Q352etb_off10.5207211
6x627x23Shared4.88.237211
6x627x27Shared9.766673.5157211
7x23E3.Q352Shared5.458.1757211
7x317x35Shared7.423335.2750211
7x237x24etb_off3.2507212
6x586x62etb_off3.1833300011
6x627x26etb_off3.1266707212
1x277x28etb_off3.0966700212
E2.I254E2.M245etb_off2.9166700211
E2.I254E2x51Shared2.853334.9950211
E2.M245NT.P88etb_off2.7966700212
2x602x64etb_off2.7466700212
E1x49E2.L252etb_off2.7133300211
7x42Ligetb_off2.14001410
E2.I254E2.L252etb_off1.9033300211
E2.I242E2.R253Shared1.673334.3852022
7x23E3.D354etb_off1.5866707212
3x21E1x50etb_off1.4066700021
E2.Y247NT.P88etb_off1.3900212
7x277x31etb_off1.3833300211
1x221x25etb_off1.3700021
1x251x26etb_off1.3666700212
E2.D246E2.G249Shared1.116670.840212
E2.L252E2.S250Shared0.54.5050212
6x58Ligetb_on_gp011.2550010
E2.M245Ligetb_on_gp013.990210
E3.Q352Ligetb_on_gp011.1257210
6x62Ligetb_on_gp06.027210
7x23Ligetb_on_gp08.7357210
E2.Y247Ligetb_on_gp026.470210
7x27Ligetb_on_gp012.2350210
E2.I254Ligetb_on_gp011.3350210
1x25Ligetb_on_gp08.9150210
E2.L252Ligetb_on_gp04.3850210
7x31Ligetb_on_gp06.730210
7x34Ligetb_on_gp014.670210
E2x51Ligetb_on_gp03.9050210
E1.E165Ligetb_on_gp05.2050010
7x35Ligetb_on_gp07.24210
2x59Ligetb_on_gp04.4150210
E1x50Ligetb_on_gp04.6952210
7x23NT.C90etb_on_gp03.487212
1x257x24etb_on_gp04.910212
1x257x28etb_on_gp03.0950212
1x271x32etb_on_gp02.910212
1x272x64etb_on_gp03.570212
1x322x64etb_on_gp04.230222
2x533x36etb_on_gp04.1551211
2x536x48etb_on_gp03.1751211
2x542x57etb_on_gp02.94501422
2x547x42etb_on_gp05.4201421
2x562x60etb_on_gp05.3850221
2x563x32etb_on_gp013.7050221
2x577x42etb_on_gp03.09511421
2x592x60etb_on_gp04.250211
2x607x38etb_on_gp07.080211
2x647x35etb_on_gp014.6550221
E1x49E1x51etb_on_gp08.8550212
3x335x461etb_on_gp03.5851212
5x406x55etb_on_gp07.740021
5x425x43etb_on_gp03.421221
5x435x461etb_on_gp03.5151212
6x486x51etb_on_gp04.5551211
6x517x34etb_on_gp02.711211
1x27Ligetb_on_gp02.8550210
1x277x35etb_on_gp04.230211
2x567x38etb_on_gp04.20221
E2.M245E2.Y247etb_on_gp02.9950211
5x39E2x52etb_on_gp02.821222
E1x49Ligetb_on_gp02.520210
1x281x31etb_on_gp01.860022
3x21E1x52etb_on_gp01.5050022
E2.D246Ligetb_on_gp01.3850210

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Difference Members
Id Description
etb_on_gp 8IY5-ETB-Endothelin-1-Gi1/β1/γ2
8HBD-ETB-IRL1620-Gi1/β1/γ2
etb_off 5X93-ETB-K-8794
5XPR-ETB-Bosentan
6K1Q-ETB-IRL2500
Network Difference
Value etb_on_gp etb_off
Imin 2.665 3.42333
Number of Linked Nodes 908 307
Number of Specific Nodes 607 (66.85%) 6  (1.95%)
Number of Shared Nodes 301 (33.15%) 301  (98.05%)
Number of Links 1147 345
Number of Specific Links 959 (83.61%) 157  (45.51%)
Number of Shared Links 188 (16.39%) 188  (54.49%)
Number of Hubs 196 46
Number of Specific Hubs 164 (83.67%) 14  (30.43%)
Number of Shared Hubs 32 (16.33%) 32  (69.57%)
Average % Shared Neighbours (Jaccard) 13.76
Average % Shared Neighbours (Otsuka) 17.09
Average % Shared Neighbours (Overlap Coefficient) 20.11
Average % Shared Cliques (k3-6) 51.82
Graphlets Similarity 0.669589
Paths Difference
Value etb_on_gp etb_off
Number Of Nodes in MetaPath 128 83
Specific Nodes in MetaPath 101 (78.91%) 56  (67.47%)
Shared Nodes in MetaPath 301 (33.15%) 301  (33.15%)
Number Of Links MetaPath 127 87
Specific Links in MetaPath 116 (91.34%) 76  (87.36%)
Shared Links in MetaPath 188 (16.39%) 188  (16.39%)
Number of Shortest Paths 1861959 67693
Length Of Smallest Path 3 3
Average Path Length 39.5373 13.4476
Length of Longest Path 82 31
Minimum Path Strength 0.625 0.543333
Average Path Strength 5.58214 5.75945
Maximum Path Strength 25.67 17.0317
Minimum Path Correlation 0.7 0.7
Average Path Correlation 0.980616 0.931708
Maximum Path Correlation 1 0.99
Minimum % Of Corr. Nodes 1.51515 4
Average % Of Corr. Nodes 36.455 50.1086
Maximum % Of Corr. Nodes 100 100
Minimum Path Hubs % 0 0
Average Path Hubs % 54.5401 44.3061
Maximum Path Hubs % 100 100

Details about the values in these tables can be found in the corresponding documentation page .

You can download a compressed (zip) file with structure(s), 3D outputs (as PyMol and VMD scripts) and numerical data files (as csv and plain text files).

Download etb_off_on_gp.zip<



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