psnGPCR

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Orange: nodes, hubs and links specific of ffa3_on_allo network

Green: nodes, hubs and links shared by both networks

Purple: nodes, hubs and links specific of ffa3_on network

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Owner: the name of the network the link belong to or "Shared" if the corresponding link is present in both networks.

Strength: the interaction strength between the two nodes or 0 if the link is not present.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Owner	ffa3_on_allo Int. Strength	ffa3_on Int. Strength	ffa3_on_allo Hub1?	ffa3_on Hub1?	ffa3_on_allo Hub2?	ffa3_on Hub2?	ConSurf1	ConSurf2
1	1x32	1x33	ffa3_on_allo	8.46	0	No	Yes	No	No	6	2
2	1x35	7x39	ffa3_on_allo	2.98	0	No	No	No	No	5	4
3	1x39	2x57	ffa3_on_allo	5.86	0	Yes	No	No	Yes	7	8
4	1x39	2x61	ffa3_on_allo	8.38	0	Yes	No	No	No	7	7
5	1x42	7x43	ffa3_on_allo	2.95	0	No	No	No	No	7	4
6	1x50	7x50	ffa3_on_allo	4.89	0	No	No	No	No	9	9
7	1x57	2x44	ffa3_on_allo	3.65	0	Yes	No	No	No	7	6
8	1x57	2x47	ffa3_on_allo	3.89	0	Yes	No	Yes	No	7	8
9	1x57	7x53	ffa3_on_allo	7.22	0	Yes	No	Yes	No	7	9
10	1x60	8x53	ffa3_on_allo	11.06	0	No	No	No	No	6	5
11	2x37	I2x53	ffa3_on_allo	3.79	0	No	No	No	No	7	5
12	2x44	2x47	ffa3_on_allo	4.42	0	No	No	Yes	No	6	8
13	2x46	7x53	ffa3_on_allo	4.69	0	No	No	Yes	No	9	9
14	2x47	7x53	ffa3_on_allo	3.75	0	Yes	No	Yes	No	8	9
15	2x49	3x35	ffa3_on_allo	3.2	0	No	No	No	No	8	8
16	2x49	4x50	ffa3_on_allo	4.94	0	No	No	Yes	Yes	8	9
17	2x53	3x32	ffa3_on_allo	4.87	0	Yes	Yes	Yes	Yes	6	6
18	2x55	2x56	ffa3_on_allo	3.65	0	No	No	No	No	4	5
19	2x57	2x60	ffa3_on_allo	3.64	0	No	Yes	Yes	No	8	6
20	2x60	3x28	ffa3_on_allo	5.27	0	Yes	No	No	No	6	5
21	E1x49	E2.T165	ffa3_on_allo	8.21	0	No	No	No	No	4	5
22	E1x49	E2.G167	ffa3_on_allo	3.18	0	No	No	No	No	4	4
23	3x21	3x24	ffa3_on_allo	3.28	0	No	No	No	No	7	6
24	3x25	E2x51	ffa3_on_allo	6.72	0	No	No	No	No	9	4
25	3x28	3x29	ffa3_on_allo	3.71	0	No	No	No	No	5	5
26	3x30	4x57	ffa3_on_allo	9.78	0	Yes	Yes	No	No	5	6
27	3x32	3x33	ffa3_on_allo	5.36	0	Yes	Yes	No	Yes	6	5
28	3x36	3x37	ffa3_on_allo	3.63	0	No	No	Yes	Yes	7	7
29	3x37	Lig	ffa3_on_allo	6.96	0	Yes	Yes	Yes	Yes	7	0
30	3x39	6x48	ffa3_on_allo	3.89	0	No	No	Yes	Yes	9	8
31	3x40	5x50	ffa3_on_allo	3.74	0	No	No	Yes	No	8	9
32	3x43	Allo2	ffa3_on_allo	15.57	0	No	No	Yes	No	8	0
33	3x50	Allo2	ffa3_on_allo	10.79	0	No	No	Yes	No	9	0
34	4x56	5x461	ffa3_on_allo	5.14	0	No	No	Yes	No	4	6
35	4x57	Lig	ffa3_on_allo	3.77	0	No	No	Yes	Yes	6	0
36	4x58	4x61	ffa3_on_allo	7.63	0	No	No	No	No	4	5
37	4x59	5x39	ffa3_on_allo	3.21	0	No	No	No	No	8	4
38	4x62	4x63	ffa3_on_allo	3.07	0	No	No	No	No	4	4
39	E2x50	E2x51	ffa3_on_allo	10.75	0	Yes	No	No	No	9	4
40	5x33	E2.F173	ffa3_on_allo	3.65	0	No	No	No	No	1	5
41	E2.Q177	E2.R174	ffa3_on_allo	9.35	0	Yes	Yes	No	No	4	6
42	5x33	E2.Q177	ffa3_on_allo	3.99	0	No	No	Yes	Yes	1	4
43	5x39	5x42	ffa3_on_allo	4.28	0	No	No	No	No	4	4
44	5x41	5x45	ffa3_on_allo	2.98	0	No	No	No	No	4	5
45	5x47	5x51	ffa3_on_allo	6.09	0	Yes	No	Yes	No	8	6
46	5x47	6x48	ffa3_on_allo	3.22	0	Yes	No	Yes	Yes	8	8
47	5x49	5x53	ffa3_on_allo	3.07	0	No	No	No	No	5	6
48	5x51	Allo2	ffa3_on_allo	4.1	0	Yes	No	Yes	No	6	0
49	5x54	5x58	ffa3_on_allo	4.99	0	No	No	Yes	Yes	8	8
50	5x54	Allo2	ffa3_on_allo	13.09	0	No	No	Yes	No	8	0
51	5x58	Allo2	ffa3_on_allo	16.66	0	Yes	Yes	Yes	No	8	0
52	5x61	5x65	ffa3_on_allo	4.15	0	No	No	Yes	No	8	8
53	6x31	I3.A215	ffa3_on_allo	4.15	0	No	No	No	No	6	4
54	6x32	I3.H217	ffa3_on_allo	5.64	0	No	No	No	No	6	4
55	6x30	6x31	ffa3_on_allo	4.26	0	No	No	No	No	6	6
56	6x41	Allo2	ffa3_on_allo	29.68	0	No	No	Yes	No	7	0
57	6x42	6x46	ffa3_on_allo	4.15	0	No	No	No	No	7	5
58	6x42	Allo2	ffa3_on_allo	4.92	0	No	No	Yes	No	7	0
59	6x44	6x47	ffa3_on_allo	4.72	0	No	No	No	No	6	8
60	6x45	6x48	ffa3_on_allo	5.36	0	Yes	Yes	Yes	Yes	9	8
61	6x45	Allo2	ffa3_on_allo	11.54	0	Yes	Yes	Yes	No	9	0
62	6x50	7x36	ffa3_on_allo	6.95	0	No	No	Yes	No	9	5
63	7x36	7x40	ffa3_on_allo	4.69	0	Yes	No	No	No	5	8
64	7x37	7x38	ffa3_on_allo	2.98	0	No	No	No	No	6	6
65	7x49	Allo2	ffa3_on_allo	3.21	0	No	No	Yes	No	9	0
66	7x52	Allo2	ffa3_on_allo	4.41	0	No	No	Yes	No	8	0
67	7x53	Allo2	ffa3_on_allo	6.25	0	Yes	No	Yes	No	9	0
68	8x54	8x58	ffa3_on_allo	9.74	0	No	No	No	No	6	5
69	7x33	7x36	ffa3_on_allo	2.89	0	Yes	No	Yes	No	4	5
70	7x34	E3.P255	ffa3_on_allo	2.88	0	No	No	No	Yes	5	3
71	1x52	1x56	ffa3_on_allo	2.85	0	No	No	Yes	Yes	6	7
72	5x55	Allo2	ffa3_on_allo	2.67	0	No	No	Yes	No	4	0
73	2x63	E1x52	ffa3_on_allo	2.65	0	No	No	No	No	5	6
74	1x43	1x44	ffa3_on_allo	2.44	0	No	No	No	No	6	4
75	3x51	3x52	ffa3_on_allo	2.44	0	Yes	No	No	No	8	5
76	3x22	E2.E154	ffa3_on_allo	2.33	0	No	No	No	No	4	4
77	I3.H217	I3.R218	ffa3_on_allo	2.26	0	No	No	No	No	4	4
78	7x33	E3.Q251	ffa3_on_allo	2.19	0	Yes	No	No	No	4	1
79	1x46	1x48	ffa3_on_allo	2.03	0	No	No	No	No	8	4
80	6x58	E3.P255	ffa3_on_allo	2.03	0	No	No	No	Yes	4	3
81	1x46	7x47	ffa3_on_allo	1.96	0	No	No	No	No	8	7
82	E2.G157	E2.S156	ffa3_on_allo	1.86	0	No	No	No	No	1	5
83	2x41	4x42	ffa3_on_allo	1.7	0	No	No	No	No	6	7
84	3x21	3x23	ffa3_on_allo	1.69	0	No	No	No	No	7	3
85	3x34	4x53	ffa3_on_allo	1.68	0	No	No	No	No	5	7
86	5x37	5x38	ffa3_on_allo	1.64	0	No	No	No	No	2	3
87	3x55	5x64	ffa3_on_allo	1.62	0	No	No	No	No	7	5
88	4x46	4x47	ffa3_on_allo	1.62	0	Yes	No	No	No	7	3
89	5x62	6x38	ffa3_on_allo	1.6	0	No	No	No	No	5	7
90	2x42	3x45	ffa3_on_allo	1.58	0	Yes	Yes	No	No	7	6
91	6x56	6x60	ffa3_on_allo	1.54	0	No	No	No	No	5	4
92	E2.E154	E2x50	ffa3_on_allo	1.52	0	No	No	Yes	No	4	9
93	2x42	4x45	ffa3_on_allo	1.49	0	Yes	Yes	No	No	7	5
94	5x46	5x461	ffa3_on_allo	1.49	0	No	No	Yes	No	4	6
95	1x40	2x61	ffa3_on_allo	1.41	0	No	No	No	No	5	7
96	5x51	5x52	ffa3_on_allo	1.38	0	Yes	No	No	No	6	3
97	1x36	1x37	ffa3_on_allo	1.32	0	No	No	No	No	5	5
98	1x58	I1.R44	ffa3_on_allo	1.31	0	No	No	No	No	3	6
99	1x31	1x32	Shared	3.83	1.28	No	No	No	Yes	4	6
100	1x33	1x34	Shared	4.56	5.69	No	No	No	No	2	5
101	1x36	1x40	Shared	3.65	2.44	No	No	No	No	5	5
102	1x38	7x39	Shared	5.96	4.47	No	No	No	No	5	4
103	1x39	2x60	Shared	5.14	4.12	Yes	No	Yes	No	7	6
104	1x39	7x42	Shared	4.99	4.99	Yes	No	No	Yes	7	6
105	1x40	1x41	Shared	6.09	4.87	No	No	No	No	5	5
106	1x42	7x42	Shared	3.14	1.57	No	No	No	Yes	7	6
107	1x42	7x47	Shared	3.38	5.07	No	No	No	No	7	7
108	1x43	1x47	Shared	8.53	8.53	No	No	No	No	6	6
109	1x43	2x58	Shared	7.22	14.45	No	No	No	No	6	9
110	1x49	7x50	Shared	9.85	8.21	No	No	No	No	7	9
111	1x50	2x51	Shared	4.12	6.87	No	No	No	No	9	7
112	1x52	8x54	Shared	7.31	3.65	No	No	No	No	6	6
113	1x54	2x47	Shared	2.95	2.95	No	No	Yes	No	7	8
114	1x54	2x51	Shared	4.15	9.69	No	No	No	No	7	7
115	1x56	8x50	Shared	5.02	7.54	Yes	Yes	No	No	7	8
116	1x56	8x53	Shared	5.6	7	Yes	Yes	No	No	7	5
117	1x56	8x57	Shared	5.71	2.85	Yes	Yes	No	No	7	4
118	1x57	2x43	Shared	6.09	7.31	Yes	No	Yes	Yes	7	8
119	1x57	8x50	Shared	5.36	4.29	Yes	No	No	No	7	8
120	1x59	I1.R44	Shared	3	3	No	No	No	No	4	6
121	1x60	I1.R45	Shared	4.95	6.19	No	No	No	No	6	5
122	1x60	2x40	Shared	4.15	11.06	No	No	No	No	6	7
123	I1.R45	I1.R46	Shared	11.73	6.4	No	No	No	No	5	6
124	4x39	I1.P47	Shared	4.93	4.93	No	No	No	No	3	6
125	2x37	2x39	Shared	4.81	3.21	No	No	No	Yes	7	7
126	2x37	2x40	Shared	4.38	10.22	No	No	No	No	7	7
127	2x38	3x49	Shared	6.03	6.03	No	No	No	Yes	6	8
128	2x39	2x43	Shared	2.98	2.98	No	Yes	Yes	Yes	7	8
129	2x42	3x46	Shared	2.98	4.47	Yes	Yes	No	No	7	8
130	2x42	3x49	Shared	9.28	9.28	Yes	Yes	No	Yes	7	8
131	2x42	4x46	Shared	3	3	Yes	Yes	Yes	No	7	7
132	2x43	3x46	Shared	2.98	2.98	Yes	Yes	No	No	8	8
133	2x43	7x53	Shared	8.21	11.72	Yes	Yes	Yes	No	8	9
134	2x45	2x48	Shared	4.12	6.87	Yes	Yes	No	No	9	6
135	2x45	3x42	Shared	7.25	4.83	Yes	Yes	Yes	Yes	9	7
136	2x45	4x46	Shared	4.47	4.47	Yes	Yes	Yes	No	9	7
137	2x45	4x50	Shared	7.91	9.04	Yes	Yes	Yes	Yes	9	9
138	2x46	3x42	Shared	8.53	7.31	No	No	Yes	Yes	9	7
139	2x49	3x38	Shared	4.5	3	No	No	No	Yes	8	6
140	2x50	7x46	Shared	8.83	8.83	No	No	No	No	9	8
141	2x50	7x49	Shared	5.32	5.32	No	No	No	No	9	9
142	2x52	3x31	Shared	6.92	4.15	No	No	Yes	Yes	7	5
143	2x53	2x54	Shared	4.15	4.15	Yes	Yes	No	Yes	6	5
144	2x53	3x35	Shared	13.27	10.32	Yes	Yes	No	No	6	8
145	2x53	7x46	Shared	3	3	Yes	Yes	No	No	6	8
146	2x54	7x46	Shared	3	6.01	No	Yes	No	No	5	8
147	2x56	3x31	Shared	6.09	4.87	No	No	Yes	Yes	5	5
148	2x59	3x24	Shared	3.65	8.53	No	Yes	No	No	6	6
149	2x59	3x28	Shared	5.28	5.28	No	Yes	No	No	6	5
150	2x60	E1x50	Shared	5	4	Yes	No	No	Yes	6	9
151	2x60	3x32	Shared	11.76	9.62	Yes	No	Yes	Yes	6	6
152	2x63	E1x51	Shared	7.86	3.14	No	No	No	No	5	2
153	E1.M79	E2x52	Shared	7.07	5.65	No	No	No	No	4	5
154	E1x49	E2.T168	Shared	4.11	2.74	No	No	No	No	4	3
155	3x25	E1x50	Shared	13.06	6.53	No	No	No	Yes	9	9
156	E1x50	E2x50	Shared	10.45	5.22	No	Yes	Yes	No	9	9
157	3x21	E1x52	Shared	4.93	4.93	No	No	No	No	7	6
158	3x24	E1x52	Shared	4.15	4.15	No	No	No	No	6	6
159	3x25	E2x50	Shared	7.28	7.28	No	No	Yes	No	9	9
160	3x29	E2x51	Shared	5.79	4.35	No	No	No	No	5	4
161	3x30	3x31	Shared	7.31	6.09	Yes	Yes	Yes	Yes	5	5
162	3x30	4x61	Shared	9.28	11.35	Yes	Yes	No	No	5	5
163	3x32	7x38	Shared	7.31	3.65	Yes	Yes	No	No	6	6
164	3x33	Lig	Shared	24.59	27.43	No	Yes	Yes	Yes	5	0
165	3x34	4x57	Shared	5.07	6.76	No	No	No	No	5	6
166	3x36	6x48	Shared	5.02	3.77	No	No	Yes	Yes	7	8
167	3x36	7x41	Shared	4.64	4.64	No	No	No	No	7	7
168	3x37	5x43	Shared	8.38	3.59	Yes	Yes	No	Yes	7	6
169	3x37	5x461	Shared	8.21	11.72	Yes	Yes	Yes	No	7	6
170	3x37	6x51	Shared	13.9	4.96	Yes	Yes	No	Yes	7	6
171	3x38	3x42	Shared	13.4	13.4	No	Yes	Yes	Yes	6	7
172	3x38	4x50	Shared	10.25	10.25	No	Yes	Yes	Yes	6	9
173	3x41	4x49	Shared	4.76	7.94	No	No	No	No	6	6
174	3x41	5x461	Shared	4.15	2.77	No	No	Yes	No	6	6
175	3x42	4x50	Shared	8.02	5.01	Yes	Yes	Yes	Yes	7	9
176	3x47	5x54	Shared	9.59	6.4	No	No	No	No	9	8
177	3x47	5x57	Shared	5.16	3.44	No	No	No	No	9	6
178	3x47	5x58	Shared	10.17	6.36	No	No	Yes	Yes	9	8
179	3x48	5x57	Shared	3.27	4.91	No	No	No	No	6	6
180	3x50	5x58	Shared	8.23	6.17	No	No	Yes	Yes	9	8
181	3x51	3x55	Shared	5.55	4.16	Yes	No	No	No	8	7
182	3x51	5x57	Shared	5.59	6.98	Yes	No	No	No	8	6
183	3x51	5x60	Shared	8.55	11.76	Yes	No	No	No	8	4
184	3x52	I2x52	Shared	3.42	12.53	No	No	No	Yes	5	5
185	3x54	5x61	Shared	4.47	4.47	No	Yes	No	No	8	8
186	3x54	5x65	Shared	4.47	1.49	No	Yes	Yes	No	8	8
187	I2x52	I2x56	Shared	10	14.99	No	Yes	No	Yes	5	4
188	4x38	I2x52	Shared	13.99	15.99	No	No	No	Yes	6	5
189	I2x55	I2x56	Shared	3.88	10.35	No	No	No	Yes	4	4
190	4x38	4x41	Shared	26.87	25.7	No	No	No	No	6	3
191	4x56	5x43	Shared	3.94	6.57	No	No	No	Yes	4	6
192	4x60	Lig	Shared	10.61	11.74	No	No	Yes	Yes	5	0
193	E2.F155	E2.S156	Shared	11.89	15.85	No	No	No	No	4	5
194	E2.D158	E2.S156	Shared	5.89	2.94	No	No	No	No	2	5
195	E2.G157	E2.R174	Shared	3	6	No	No	No	No	1	6
196	E2.T168	E2x52	Shared	10.32	7.37	No	No	No	No	3	5
197	E2.F173	E2.Q177	Shared	7.03	3.51	No	No	Yes	Yes	5	4
198	E2.D176	E2.R174	Shared	3.57	3.57	No	No	No	No	4	6
199	E2.D176	E2.Q177	Shared	11.75	10.44	No	No	Yes	Yes	4	4
200	5x36	5x40	Shared	3.64	12.15	No	Yes	Yes	Yes	4	5
201	5x37	6x59	Shared	8.21	9.38	No	No	No	No	2	5
202	5x40	6x55	Shared	12.41	14.67	Yes	Yes	No	Yes	5	5
203	5x40	7x34	Shared	7.46	8.53	Yes	Yes	No	No	5	5
204	5x40	Lig	Shared	21.64	12.31	Yes	Yes	Yes	Yes	5	0
205	5x41	6x59	Shared	9.38	19.93	No	No	No	No	4	5
206	5x43	Lig	Shared	10.07	4.78	No	Yes	Yes	Yes	6	0
207	5x44	6x55	Shared	7.32	4.39	No	No	No	Yes	5	5
208	5x47	6x45	Shared	6.43	7.5	Yes	No	Yes	Yes	8	9
209	5x47	6x52	Shared	29	30.21	Yes	No	No	No	8	8
210	5x49	5x50	Shared	3.53	3.53	No	No	Yes	No	5	9
211	5x51	6x45	Shared	3.65	9.74	Yes	No	Yes	Yes	6	9
212	5x56	5x60	Shared	16.46	16.46	No	No	No	No	4	4
213	5x58	6x38	Shared	5.05	7.57	Yes	Yes	No	No	8	7
214	5x63	5x67	Shared	10	3	No	No	No	No	3	4
215	5x65	6x30	Shared	3.64	3.64	Yes	No	No	No	8	6
216	5x65	6x34	Shared	4.47	4.47	Yes	No	No	No	8	7
217	5x66	6x31	Shared	7.51	6	No	No	No	No	4	6
218	I3.R218	I3.S216	Shared	7.91	2.64	No	No	No	No	4	4
219	6x30	I3.S216	Shared	3.95	1.32	No	No	No	No	6	4
220	6x37	7x56	Shared	3	4.5	No	No	No	No	7	6
221	6x44	7x48	Shared	7.39	11.82	No	No	No	No	6	7
222	6x47	7x45	Shared	7.87	9.45	No	No	No	No	8	9
223	6x48	7x45	Shared	7.25	4.83	Yes	Yes	No	No	8	9
224	6x49	6x50	Shared	4.06	4.06	No	No	No	No	4	9
225	6x50	7x40	Shared	4.93	3.28	No	No	No	No	9	8
226	6x51	7x37	Shared	6.31	3.79	No	Yes	No	No	6	6
227	6x51	Lig	Shared	15.31	7.92	No	Yes	Yes	Yes	6	0
228	6x54	7x33	Shared	7.41	3.71	No	No	Yes	No	5	4
229	6x55	Lig	Shared	12.21	8.69	No	Yes	Yes	Yes	5	0
230	6x57	E3.Q251	Shared	4.3	4.3	No	No	No	No	5	1
231	E3.E253	E3.Q251	Shared	15.29	11.47	No	No	No	No	3	1
232	E3.P255	E3.S254	Shared	3.56	3.56	No	Yes	No	No	3	4
233	7x34	Lig	Shared	5.77	13.68	No	No	Yes	Yes	5	0
234	7x36	7x37	Shared	8.83	5.05	Yes	No	No	No	5	6
235	7x45	7x49	Shared	6.73	12.12	No	No	No	No	9	9
236	7x54	8x51	Shared	4.51	2.25	No	No	No	No	6	8
237	7x54	8x54	Shared	7.22	8.25	No	No	No	No	6	6
238	8x47	8x50	Shared	3.96	2.64	No	No	No	No	8	8
239	8x53	8x56	Shared	5.2	2.6	No	No	No	No	5	5
240	3x48	5x53	Shared	2.94	2.94	No	No	No	No	6	6
241	4x63	5x35	Shared	2.94	2.94	No	No	No	No	4	1
242	8x48	8x51	Shared	2.89	2.89	No	No	No	No	5	8
243	3x26	4x61	Shared	2.78	2.78	No	No	No	No	7	5
244	1x51	2x51	Shared	2.77	2.77	No	No	No	No	4	7
245	2x44	I1.L43	Shared	2.77	2.77	No	No	No	No	6	5
246	3x55	3x56	Shared	2.67	8.01	No	No	No	No	7	6
247	7x52	7x55	Shared	2.62	5.24	No	No	No	No	8	7
248	3x53	I2x53	Shared	2.54	8.9	No	No	No	No	8	5
249	1x35	1x39	Shared	2.52	2.52	No	No	Yes	No	5	7
250	7x32	7x33	Shared	2.45	2.45	No	No	Yes	No	2	4
251	6x37	7x55	Shared	2.44	3.65	No	No	No	No	7	7
252	5x58	5x61	Shared	2.34	8.21	Yes	Yes	No	No	8	8
253	5x48	5x50	Shared	2.03	2.03	No	No	Yes	No	4	9
254	1x33	1x36	Shared	2	1	No	No	No	No	2	5
255	4x42	4x43	Shared	1.95	1.95	No	No	No	No	7	3
256	8x49	8x52	Shared	1.95	1.95	No	No	No	No	7	5
257	3x44	5x50	Shared	1.87	1.87	No	No	Yes	No	7	9
258	4x43	4x46	Shared	1.86	3.71	No	No	Yes	No	3	7
259	8x47	8x49	Shared	1.86	1.86	No	No	No	No	8	7
260	1x45	1x46	Shared	1.84	3.68	No	No	No	No	5	8
261	2x64	E1.S77	Shared	1.71	1.71	No	No	No	No	5	4
262	4x39	4x40	Shared	1.71	1.71	No	No	No	No	3	4
263	1x47	1x48	Shared	1.64	1.64	No	No	No	No	6	4
264	I1.L43	I1.P47	Shared	1.64	1.64	No	No	No	No	5	6
265	2x57	2x58	Shared	1.64	6.57	No	Yes	No	No	8	9
266	4x40	4x41	Shared	1.64	1.64	No	No	No	No	4	3
267	1x35	7x35	Shared	1.62	3.23	No	No	No	No	5	4
268	5x62	6x34	Shared	1.6	1.6	No	No	No	No	5	7
269	4x51	4x54	Shared	1.5	1.5	No	No	No	No	4	4
270	1x32	2x65	Shared	1.46	1.46	No	Yes	No	No	6	3
271	I2x56	I2x57	Shared	1.44	1.44	No	Yes	No	No	4	7
272	5x42	5x46	Shared	1.43	11.41	No	No	No	No	4	4
273	3x56	I2x50	Shared	1.39	1.39	No	No	No	No	6	8
274	3x27	3x31	Shared	1.38	5.54	No	No	Yes	Yes	5	5
275	5x33	5x37	Shared	1.38	1.38	No	No	No	No	1	2
276	4x63	E2.Q177	Shared	1.37	1.37	No	No	Yes	Yes	4	4
277	3x30	4x54	Shared	1.32	1.32	Yes	Yes	No	No	5	4
278	5x59	5x60	Shared	1.32	2.64	No	No	No	No	1	4
279	6x33	6x37	Shared	1.21	3.64	No	No	No	No	7	7
280	E2.E154	E2.F173	Shared	1.17	19.82	No	No	No	No	4	5
281	1x32	1x36	ffa3_on	0	23.76	No	Yes	No	No	6	5
282	1x37	1x38	ffa3_on	0	3.23	No	No	No	No	5	5
283	1x43	2x61	ffa3_on	0	6.22	No	No	No	No	6	7
284	1x47	2x54	ffa3_on	0	4.15	No	No	No	Yes	6	5
285	1x50	2x47	ffa3_on	0	4.39	No	No	Yes	No	9	8
286	1x50	2x50	ffa3_on	0	6.73	No	No	No	No	9	9
287	1x56	8x54	ffa3_on	0	5.02	Yes	Yes	No	No	7	6
288	1x60	I1.R46	ffa3_on	0	4.95	No	No	No	No	6	6
289	2x37	I1.R46	ffa3_on	0	3.92	No	No	No	No	7	6
290	2x39	3x46	ffa3_on	0	3.21	No	Yes	No	No	7	8
291	2x39	3x49	ffa3_on	0	2.85	No	Yes	No	Yes	7	8
292	2x41	2x42	ffa3_on	0	2.98	No	No	Yes	Yes	6	7
293	2x46	3x39	ffa3_on	0	4.42	No	No	No	No	9	9
294	2x48	4x50	ffa3_on	0	3.42	No	No	Yes	Yes	6	9
295	2x52	3x35	ffa3_on	0	4.42	No	No	No	No	7	8
296	2x53	2x57	ffa3_on	0	2.77	Yes	Yes	No	Yes	6	8
297	2x54	2x57	ffa3_on	0	2.77	No	Yes	No	Yes	5	8
298	2x57	3x32	ffa3_on	0	3.65	No	Yes	Yes	Yes	8	6
299	2x59	E1x50	ffa3_on	0	8.02	No	Yes	No	Yes	6	9
300	2x59	E1x52	ffa3_on	0	4.87	No	Yes	No	No	6	6
301	2x61	2x62	ffa3_on	0	4.56	No	No	No	No	7	4
302	3x22	E2.G167	ffa3_on	0	3.01	No	No	No	No	4	4
303	3x23	3x24	ffa3_on	0	2.85	No	No	No	No	3	6
304	3x30	3x34	ffa3_on	0	6.49	Yes	Yes	No	No	5	5
305	3x32	3x36	ffa3_on	0	6.28	Yes	Yes	No	No	6	7
306	3x33	4x57	ffa3_on	0	2.79	No	Yes	No	No	5	6
307	3x33	E2x51	ffa3_on	0	11.35	No	Yes	No	No	5	4
308	3x33	6x51	ffa3_on	0	3.09	No	Yes	No	Yes	5	6
309	3x37	4x57	ffa3_on	0	4.03	Yes	Yes	No	No	7	6
310	3x38	4x53	ffa3_on	0	3.15	No	Yes	No	No	6	7
311	3x40	6x45	ffa3_on	0	2.77	No	No	Yes	Yes	8	9
312	3x40	6x48	ffa3_on	0	2.77	No	No	Yes	Yes	8	8
313	3x42	4x49	ffa3_on	0	5.59	Yes	Yes	No	No	7	6
314	3x43	6x45	ffa3_on	0	9.74	No	No	Yes	Yes	8	9
315	3x49	I2x53	ffa3_on	0	6.73	No	Yes	No	No	8	5
316	3x53	3x54	ffa3_on	0	3.23	No	No	No	Yes	8	8
317	3x54	5x64	ffa3_on	0	4.61	No	Yes	No	No	8	5
318	I2x52	I2x53	ffa3_on	0	2.89	No	Yes	No	No	5	5
319	4x38	I2x56	ffa3_on	0	4.26	No	No	No	Yes	6	4
320	4x52	4x56	ffa3_on	0	9	No	No	No	No	4	4
321	4x56	5x42	ffa3_on	0	3.69	No	No	No	No	4	4
322	4x61	4x62	ffa3_on	0	3.79	No	No	No	No	5	4
323	E2.E154	E2.Q177	ffa3_on	0	14.02	No	No	Yes	Yes	4	4
324	E2.D176	E2.G157	ffa3_on	0	5.03	No	No	No	No	4	1
325	E2.G167	E2.N166	ffa3_on	0	3.39	No	No	No	No	4	3
326	5x36	5x37	ffa3_on	0	2.77	No	Yes	No	No	4	2
327	5x38	6x59	ffa3_on	0	2.78	No	No	No	No	3	5
328	5x40	E3.P255	ffa3_on	0	2.88	Yes	Yes	No	Yes	5	3
329	5x43	5x461	ffa3_on	0	4.24	No	Yes	Yes	No	6	6
330	5x45	5x46	ffa3_on	0	3.21	No	No	No	No	5	4
331	5x47	5x48	ffa3_on	0	3.01	Yes	No	No	No	8	4
332	5x51	6x46	ffa3_on	0	2.77	Yes	No	No	No	6	5
333	5x58	6x41	ffa3_on	0	3.75	Yes	Yes	No	No	8	7
334	5x64	5x67	ffa3_on	0	10.02	No	No	No	No	5	4
335	6x30	I3.A215	ffa3_on	0	2.77	No	No	No	No	6	4
336	6x33	8x48	ffa3_on	0	5.27	No	No	No	No	7	5
337	6x44	7x52	ffa3_on	0	4.43	No	No	No	No	6	8
338	6x47	6x48	ffa3_on	0	2.79	No	No	Yes	Yes	8	8
339	6x50	7x37	ffa3_on	0	3.53	No	No	No	No	9	6
340	6x51	6x52	ffa3_on	0	3.49	No	Yes	No	No	6	8
341	6x51	6x55	ffa3_on	0	10.89	No	Yes	No	Yes	6	5
342	6x51	7x38	ffa3_on	0	4.69	No	Yes	No	No	6	6
343	6x54	E3.P255	ffa3_on	0	5.34	No	No	No	Yes	5	3
344	7x33	E3.P255	ffa3_on	0	8.11	Yes	No	No	Yes	4	3
345	7x39	7x42	ffa3_on	0	4.42	No	No	No	Yes	4	6
346	7x40	7x43	ffa3_on	0	4.15	No	No	No	No	8	4
347	7x42	7x43	ffa3_on	0	2.95	No	Yes	No	No	6	4
348	8x53	8x57	ffa3_on	0	4.07	No	No	No	No	5	4
349	2x40	I1.L43	ffa3_on	0	2.71	No	No	No	No	7	5
350	E1x50	E1x51	ffa3_on	0	2.7	No	Yes	No	No	9	2
351	3x30	4x58	ffa3_on	0	2.64	Yes	Yes	No	No	5	4
352	E2.R174	E2.S156	ffa3_on	0	2.64	No	No	No	No	6	5
353	5x36	E2.F173	ffa3_on	0	2.44	No	Yes	No	No	4	5
354	6x36	6x39	ffa3_on	0	1.95	No	No	No	No	6	4
355	1x58	1x59	ffa3_on	0	1.84	No	No	No	No	3	4
356	6x57	6x58	ffa3_on	0	1.84	No	No	No	No	5	4
357	E1.G78	E1.M79	ffa3_on	0	1.75	No	No	No	No	3	4
358	1x46	1x49	ffa3_on	0	1.71	No	No	No	No	8	7
359	1x46	2x54	ffa3_on	0	1.71	No	No	No	Yes	8	5
360	4x45	4x49	ffa3_on	0	1.71	No	No	No	No	5	6
361	1x35	2x65	ffa3_on	0	1.7	No	No	No	No	5	3
362	3x45	4x45	ffa3_on	0	1.7	No	No	No	No	6	5
363	5x44	6x56	ffa3_on	0	1.7	No	No	No	No	5	5
364	5x62	6x35	ffa3_on	0	1.7	No	No	No	No	5	6
365	6x40	7x52	ffa3_on	0	1.7	No	No	No	No	5	8
366	1x53	2x47	ffa3_on	0	1.68	No	No	Yes	No	9	8
367	E3.G252	E3.Q251	ffa3_on	0	1.64	No	No	No	No	2	1
368	E3.E253	E3.G252	ffa3_on	0	1.64	No	No	No	No	3	2
369	2x65	E1.M79	ffa3_on	0	1.61	No	No	No	No	3	4
370	4x59	4x63	ffa3_on	0	1.54	No	No	No	No	8	4
371	5x40	6x58	ffa3_on	0	1.5	Yes	Yes	No	No	5	4
372	5x55	6x42	ffa3_on	0	1.5	No	No	No	No	4	7
373	1x44	1x45	ffa3_on	0	1.49	No	No	No	No	4	5
374	4x44	4x47	ffa3_on	0	1.49	No	No	No	No	3	3
375	5x61	6x34	ffa3_on	0	1.49	No	No	No	No	8	7
376	6x38	6x42	ffa3_on	0	1.49	No	No	No	No	7	7
377	6x43	6x461	ffa3_on	0	1.49	No	No	No	No	4	6
378	6x461	7x40	ffa3_on	0	1.49	No	No	No	No	6	8
379	1x32	2x64	ffa3_on	0	1.46	No	Yes	No	No	6	5
380	1x49	7x51	ffa3_on	0	1.38	No	No	No	No	7	6
381	1x52	8x58	ffa3_on	0	1.38	No	No	No	No	6	5
382	5x33	5x36	ffa3_on	0	1.38	No	No	No	Yes	1	4
383	6x32	6x35	ffa3_on	0	1.38	No	No	No	No	6	6

Orange: nodes, hubs and links specific of ffa3_on_allo network

Green: nodes, hubs and links shared by both networks

Purple: nodes, hubs and links specific of ffa3_on network

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Owner: the name of the network the hub belong to or "Shared" if the corresponding hub is present in both networks.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub in the corresponding network.

Num Of Links: the number of links of the corresponding hub in the corresponding network.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Owner	ffa3_on_allo Avg Int. Strength	ffa3_on Avg Int. Strength	ffa3_on_allo Num Of Links	ffa3_on Num Of Links	ConSurf
1	1x39	ffa3_on_allo	5.378	3.87667	5	3	7
2	1x57	ffa3_on_allo	5.242	5.8	5	2	7
3	2x47	ffa3_on_allo	3.7525	3.00667	4	3	8
4	2x60	ffa3_on_allo	6.162	5.91333	5	3	6
5	3x51	ffa3_on_allo	5.5325	7.63333	4	3	8
6	4x46	ffa3_on_allo	2.7375	3.72667	4	3	7
7	E2x50	ffa3_on_allo	7.5	6.25	4	2	9
8	5x461	ffa3_on_allo	4.7475	6.24333	4	3	6
9	5x47	ffa3_on_allo	11.185	13.5733	4	3	8
10	5x50	ffa3_on_allo	2.7925	2.47667	4	3	9
11	5x51	ffa3_on_allo	3.805	6.255	4	2	6
12	5x65	ffa3_on_allo	4.1825	3.2	4	3	8
13	7x33	ffa3_on_allo	3.735	4.75667	4	3	4
14	7x36	ffa3_on_allo	5.84	5.05	4	1	5
15	7x53	ffa3_on_allo	6.024	11.72	5	1	9
16	Allo2	ffa3_on_allo	10.2408	0	12	0	0
17	1x56	Shared	4.795	5.6025	4	4	7
18	2x42	Shared	3.666	4.9325	5	4	7
19	2x43	Shared	5.065	6.2475	4	4	8
20	2x45	Shared	5.9375	6.3025	4	4	9
21	2x53	Shared	6.3225	5.06	4	4	6
22	3x30	Shared	6.9225	5.578	4	5	5
23	3x31	Shared	5.425	5.1625	4	4	5
24	3x32	Shared	7.325	5.8	4	4	6
25	3x37	Shared	8.216	6.075	5	4	7
26	3x42	Shared	9.3	7.228	4	5	7
27	4x50	Shared	7.78	6.93	4	4	9
28	E2.Q177	Shared	6.698	7.335	5	4	4
29	5x40	Shared	11.2875	8.67333	4	6	5
30	5x58	Shared	7.90667	6.412	6	5	8
31	6x45	Shared	6.745	7.4375	4	4	9
32	6x48	Shared	4.948	3.54	5	4	8
33	Lig	Shared	12.3256	12.3643	9	7	0
34	1x32	ffa3_on	4.58333	6.99	3	4	6
35	2x39	ffa3_on	3.895	3.0625	2	4	7
36	2x54	ffa3_on	3.575	3.758	2	5	5
37	2x57	ffa3_on	3.71333	3.94	3	4	8
38	2x59	ffa3_on	4.465	6.675	2	4	6
39	E1x50	ffa3_on	9.50333	5.294	3	5	9
40	3x33	ffa3_on	14.975	11.165	2	4	5
41	3x38	ffa3_on	9.38333	7.45	3	4	6
42	3x49	ffa3_on	7.655	6.2225	2	4	8
43	3x54	ffa3_on	4.47	3.45	2	4	8
44	I2x52	ffa3_on	9.13667	11.6	3	4	5
45	I2x56	ffa3_on	5.10667	7.76	3	4	4
46	5x36	ffa3_on	3.64	4.685	1	4	4
47	5x43	ffa3_on	7.46333	4.795	3	4	6
48	6x51	ffa3_on	11.84	5.54714	3	7	6
49	6x55	ffa3_on	10.6467	9.66	3	4	5
50	E3.P255	ffa3_on	2.82333	4.9725	3	4	3
51	7x42	ffa3_on	4.065	3.4825	2	4	6

Orange: nodes, hubs and links specific of ffa3_on_allo network

Green: nodes, hubs and links shared by both networks

Purple: nodes, hubs and links specific of ffa3_on network

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Owner: the name of the network the link belong to or "Shared" if the corresponding link is present in both networks.

Recurrence: the relative Recurrence in the filtered pool of shortest paths.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Owner	ffa3_on_allo Recurrence	ffa3_on Recurrence	ffa3_on_allo Hub1?	ffa3_on Hub1?	ffa3_on_allo Hub2?	ffa3_on Hub2?	ConSurf1	ConSurf2
1	1x33	1x36	ffa3_on_allo	10.3876	3.27777	No	No	No	No	2	5
2	1x36	1x40	ffa3_on_allo	14.4391	3.27777	No	No	No	No	5	5
3	1x40	2x61	ffa3_on_allo	18.4297	0	No	No	No	No	5	7
4	1x39	2x61	ffa3_on_allo	20.4021	0	Yes	No	No	No	7	7
5	1x42	7x42	ffa3_on_allo	10.3419	5.50686	No	No	No	Yes	7	6
6	2x57	2x58	ffa3_on_allo	10.2201	5.84629	No	Yes	No	No	8	9
7	2x53	3x32	ffa3_on_allo	84.449	0	Yes	Yes	Yes	Yes	6	6
8	2x50	7x49	ffa3_on_allo	70.0784	1.14494	No	No	No	No	9	9
9	7x49	Allo2	ffa3_on_allo	72.6906	0	No	No	Yes	No	9	0
10	7x53	Allo2	ffa3_on_allo	88.7823	0	Yes	No	Yes	No	9	0
11	2x47	7x53	ffa3_on_allo	20.7981	0	Yes	No	Yes	No	8	9
12	1x54	2x47	ffa3_on_allo	13.0607	2.81676	No	No	Yes	No	7	8
13	1x54	2x51	ffa3_on_allo	10.9207	2.81676	No	No	No	No	7	7
14	1x57	7x53	ffa3_on_allo	37.362	0	Yes	No	Yes	No	7	9
15	1x52	1x56	ffa3_on_allo	11.7813	0	No	No	Yes	Yes	6	7
16	1x52	8x54	ffa3_on_allo	10.0525	2.78636	No	No	No	No	6	6
17	2x43	7x53	ffa3_on_allo	25.5655	1.23613	Yes	Yes	Yes	No	8	9
18	1x57	2x44	ffa3_on_allo	10.6923	0	Yes	No	No	No	7	6
19	2x39	2x43	ffa3_on_allo	14.8884	7.20401	No	Yes	Yes	Yes	7	8
20	2x44	I1.L43	ffa3_on_allo	16.0079	2.38107	No	No	No	No	6	5
21	I1.L43	I1.P47	ffa3_on_allo	12.8475	4.5899	No	No	No	No	5	6
22	2x53	3x35	ffa3_on_allo	17.6377	5.77537	Yes	Yes	No	No	6	8
23	2x49	3x35	ffa3_on_allo	16.9142	0	No	No	No	No	8	8
24	2x49	4x50	ffa3_on_allo	14.4163	0	No	No	Yes	Yes	8	9
25	2x45	4x50	ffa3_on_allo	10.9055	2.08217	Yes	Yes	Yes	Yes	9	9
26	2x46	3x42	ffa3_on_allo	13.6852	2.90288	No	No	Yes	Yes	9	7
27	3x32	3x33	ffa3_on_allo	27.0962	0	Yes	Yes	No	Yes	6	5
28	3x33	Lig	ffa3_on_allo	26.7611	4.35179	No	Yes	Yes	Yes	5	0
29	4x57	Lig	ffa3_on_allo	27.911	0	No	No	Yes	Yes	6	0
30	3x30	4x57	ffa3_on_allo	22.0928	0	Yes	Yes	No	No	5	6
31	3x30	3x31	ffa3_on_allo	10.5019	7.70049	Yes	Yes	Yes	Yes	5	5
32	2x60	3x28	ffa3_on_allo	19.6025	0	Yes	No	No	No	6	5
33	2x59	3x28	ffa3_on_allo	15.3987	1.64142	No	Yes	No	No	6	5
34	2x59	3x24	ffa3_on_allo	13.2435	3.25244	No	Yes	No	No	6	6
35	E1x50	E2x50	ffa3_on_allo	39.8142	1.63635	No	Yes	Yes	No	9	9
36	3x37	Lig	ffa3_on_allo	36.5776	0	Yes	Yes	Yes	Yes	7	0
37	3x36	3x37	ffa3_on_allo	56.7512	0	No	No	Yes	Yes	7	7
38	3x36	6x48	ffa3_on_allo	57.4671	7.12802	No	No	Yes	Yes	7	8
39	5x54	Allo2	ffa3_on_allo	38.2301	0	No	No	Yes	No	8	0
40	3x47	5x54	ffa3_on_allo	37.004	1.41851	No	No	No	No	9	8
41	3x48	5x57	ffa3_on_allo	24.4079	2.83196	No	No	No	No	6	6
42	3x48	5x53	ffa3_on_allo	20.9657	1.41851	No	No	No	No	6	6
43	5x49	5x53	ffa3_on_allo	17.5082	0	No	No	No	No	5	6
44	5x49	5x50	ffa3_on_allo	14.0355	1.61609	No	No	Yes	No	5	9
45	5x58	Allo2	ffa3_on_allo	61.8917	0	Yes	Yes	Yes	No	8	0
46	3x51	5x57	ffa3_on_allo	48.3817	9.7472	Yes	No	No	No	8	6
47	3x51	3x55	ffa3_on_allo	13.7461	4.23527	Yes	No	No	No	8	7
48	3x51	5x60	ffa3_on_allo	10.479	4.23527	Yes	No	No	No	8	4
49	3x51	3x52	ffa3_on_allo	22.2298	0	Yes	No	No	No	8	5
50	3x52	I2x52	ffa3_on_allo	18.9095	1.41851	No	No	No	Yes	5	5
51	5x61	5x65	ffa3_on_allo	18.1098	0	No	No	Yes	No	8	8
52	I2x52	I2x56	ffa3_on_allo	10.8903	4.09849	No	Yes	No	Yes	5	4
53	E2.E154	E2x50	ffa3_on_allo	37.7351	0	No	No	Yes	No	4	9
54	E2.E154	E2.F173	ffa3_on_allo	34.1939	1.88459	No	No	No	No	4	5
55	E2.Q177	E2.R174	ffa3_on_allo	10.3039	0	Yes	Yes	No	No	4	6
56	5x33	E2.F173	ffa3_on_allo	12.1925	0	No	No	No	No	1	5
57	5x33	5x37	ffa3_on_allo	10.578	0.0151983	No	No	No	No	1	2
58	6x45	Allo2	ffa3_on_allo	55.7612	0	Yes	Yes	Yes	No	9	0
59	6x45	6x48	ffa3_on_allo	53.545	0	Yes	Yes	Yes	Yes	9	8
60	5x65	6x30	ffa3_on_allo	14.9037	5.75004	Yes	No	No	No	8	6
61	7x52	Allo2	ffa3_on_allo	10.1363	0	No	No	Yes	No	8	0
62	7x36	7x37	ffa3_on_allo	20.7067	1.71235	Yes	No	No	No	5	6
63	7x33	7x36	ffa3_on_allo	12.6038	0	Yes	No	Yes	No	4	5
64	2x57	2x60	ffa3_on_allo	11.4157	0	No	Yes	Yes	No	8	6
65	2x46	7x53	ffa3_on_allo	13.7004	0	No	No	Yes	No	9	9
66	1x39	2x60	Shared	39.4182	36.3392	Yes	No	Yes	No	7	6
67	1x39	7x42	Shared	12.3068	11.3684	Yes	No	No	Yes	7	6
68	2x60	3x32	Shared	100	51.6085	Yes	No	Yes	Yes	6	6
69	2x53	7x46	Shared	68.403	12.417	Yes	Yes	No	No	6	8
70	2x50	7x46	Shared	69.652	22.0173	No	No	No	No	9	8
71	1x57	8x50	Shared	31.3381	28.2233	Yes	No	No	No	7	8
72	1x56	8x50	Shared	24.286	23.5017	Yes	Yes	No	No	7	8
73	2x37	2x39	Shared	12.9388	22.5797	No	No	No	Yes	7	7
74	2x45	4x46	Shared	13.6623	95.9978	Yes	Yes	Yes	No	9	7
75	2x42	4x46	Shared	10.578	94.6299	Yes	Yes	Yes	No	7	7
76	2x42	3x46	Shared	12.8779	35.9947	Yes	Yes	No	No	7	8
77	2x43	3x46	Shared	13.9669	24.2819	Yes	Yes	No	No	8	8
78	2x60	E1x50	Shared	45.0994	17.549	Yes	No	No	Yes	6	9
79	3x37	5x461	Shared	16.0536	74.9734	Yes	Yes	Yes	No	7	6
80	6x51	7x37	Shared	16.1678	18.2076	No	Yes	No	No	6	6
81	3x47	5x57	Shared	74.0309	13.7748	No	No	No	No	9	6
82	3x47	5x58	Shared	40.195	16.4091	No	No	Yes	Yes	9	8
83	5x58	5x61	Shared	21.5977	23.679	Yes	Yes	No	No	8	8
84	E2.F173	E2.Q177	Shared	20.0899	18.7446	No	No	Yes	Yes	5	4
85	3x37	6x51	Shared	14.2259	72.4454	Yes	Yes	No	Yes	7	6
86	1x32	2x65	ffa3_on	2.1019	14.4486	No	Yes	No	No	6	3
87	1x35	2x65	ffa3_on	0	23.4358	No	No	No	No	5	3
88	1x35	1x39	ffa3_on	8.06489	26.2121	No	No	Yes	No	5	7
89	2x57	3x32	ffa3_on	0	46.7754	No	Yes	Yes	Yes	8	6
90	2x54	2x57	ffa3_on	0	23.6486	No	Yes	No	Yes	5	8
91	2x53	2x57	ffa3_on	0	16.9968	Yes	Yes	No	Yes	6	8
92	1x50	2x50	ffa3_on	0	19.4995	No	No	No	No	9	9
93	2x54	7x46	ffa3_on	1.10426	12.2448	No	Yes	No	No	5	8
94	3x32	7x38	ffa3_on	9.86216	84.7763	Yes	Yes	No	No	6	6
95	6x51	7x38	ffa3_on	0	85.592	No	Yes	No	No	6	6
96	3x41	5x461	ffa3_on	4.33326	100	No	No	Yes	No	6	6
97	3x41	4x49	ffa3_on	2.17044	99.7062	No	No	No	No	6	6
98	3x42	4x49	ffa3_on	0	98.7639	Yes	Yes	No	No	7	6
99	2x45	3x42	ffa3_on	6.58747	94.7363	Yes	Yes	Yes	Yes	9	7
100	1x57	2x43	ffa3_on	3.30516	29.2619	Yes	No	Yes	Yes	7	8
101	1x56	8x54	ffa3_on	0	18.618	Yes	Yes	No	No	7	6
102	2x39	3x46	ffa3_on	0	10.882	No	Yes	No	No	7	8
103	2x42	3x49	ffa3_on	4.38657	58.088	Yes	Yes	No	Yes	7	8
104	2x39	3x49	ffa3_on	0	18.6585	No	Yes	No	Yes	7	8
105	2x37	2x40	ffa3_on	7.54703	13.3036	No	No	No	No	7	7
106	3x49	I2x53	ffa3_on	0	53.792	No	Yes	No	No	8	5
107	I2x52	I2x53	ffa3_on	0	11.9814	No	Yes	No	No	5	5
108	3x34	4x57	ffa3_on	4.24187	16.9056	No	No	No	No	5	6
109	3x30	3x34	ffa3_on	0	15.5023	Yes	Yes	No	No	5	5
110	3x37	4x57	ffa3_on	0	14.0787	Yes	Yes	No	No	7	6
111	6x51	Lig	ffa3_on	3.26708	20.0567	No	Yes	Yes	Yes	6	0
112	5x43	Lig	ffa3_on	1.80489	26.2273	No	Yes	Yes	Yes	6	0
113	3x53	I2x53	ffa3_on	2.07905	44.5615	No	No	No	No	8	5
114	3x53	3x54	ffa3_on	0	43.5078	No	No	No	Yes	8	8
115	3x54	5x61	ffa3_on	1.7135	28.8262	No	Yes	No	No	8	8
116	6x51	6x55	ffa3_on	0	19.1651	No	Yes	No	Yes	6	5
117	5x40	6x55	ffa3_on	0.0837712	15.7911	Yes	Yes	No	Yes	5	5
118	5x36	5x40	ffa3_on	2.12474	33.0564	No	Yes	Yes	Yes	4	5
119	5x36	E2.F173	ffa3_on	0	22.2605	No	Yes	No	No	4	5
120	5x40	Lig	ffa3_on	4.15048	35.6401	Yes	Yes	Yes	Yes	5	0
121	E2.D176	E2.Q177	ffa3_on	2.1019	11.3177	No	No	Yes	Yes	4	4
122	6x51	6x52	ffa3_on	0	14.864	No	Yes	No	No	6	8
123	5x47	6x52	ffa3_on	3.328	13.3897	Yes	No	No	No	8	8
124	3x54	5x65	ffa3_on	0.0609245	11.3785	No	Yes	Yes	No	8	8
125	7x54	8x54	ffa3_on	6.09245	14.7475	No	No	No	No	6	6
126	7x54	8x51	ffa3_on	4.07433	13.4455	No	No	No	No	6	8
127	8x48	8x51	ffa3_on	2.04097	12.1232	No	No	No	No	5	8
128	6x33	8x48	ffa3_on	0	10.7807	No	No	No	No	7	5
129	6x50	7x40	ffa3_on	0.00761557	12.8375	No	No	No	No	9	8
130	6x50	7x37	ffa3_on	0	15.3909	No	No	No	No	9	6
131	5x43	5x461	ffa3_on	0	25.3052	No	Yes	Yes	No	6	6

Here, those paths that begin and end at given residue pair(s) or that pass through a residue are used to generate a novel metapath. Such a path filtering is particularly recommended if some information on allosteric residues is available. The selection syntax for a residue pair ("Pairs") is C:C:c534,A:A:?600 (the lower-case "c" stands for cytosine and "?" indicates any non standard amino acid or nucleotide residue). Selection of more than one apical residue pair has the following syntax: C:C:c534,A:A:?600,C:C:c534,A:A:E41. Only one residue can be selected as a tail ("Tail"). For midway residue(s), each residue must be separated by a comma as well e.g. A:A:?600,A:A:E41.

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Node1	Node2	Owner	Net1LinkStrength	Net2LinkStrength	Comm1	Comm2	Node1Shell	Node2Shell
3x30	3x34	ffa3_on	6.49	0	0	0	2	2
3x32	3x36	ffa3_on	6.28	0	0	0	2	2
3x32	7x38	Shared	3.65	7.31	0	0	2	2
3x33	4x57	ffa3_on	2.79	0	1	0	1	1
3x33	E2x51	ffa3_on	11.35	0	1	0	1	2
3x33	6x51	ffa3_on	3.09	0	1	0	1	1
3x33	Lig	Shared	27.43	24.59	1	0	1	0
3x34	4x57	Shared	6.76	5.07	0	0	2	1
3x37	4x57	ffa3_on	4.03	0	1	3	1	1
3x37	5x43	Shared	3.59	8.38	1	3	1	1
3x37	5x461	Shared	11.72	8.21	1	3	1	2
3x37	6x51	Shared	4.96	13.9	1	3	1	1
4x56	5x43	Shared	6.57	3.94	0	0	2	1
4x60	Lig	Shared	11.74	10.61	0	0	1	0
5x36	5x40	Shared	12.15	3.64	1	0	2	1
5x40	6x55	Shared	14.67	12.41	1	3	1	1
5x40	E3.P255	ffa3_on	2.88	0	1	3	1	2
5x40	7x34	Shared	8.53	7.46	1	3	1	1
5x40	Lig	Shared	12.31	21.64	1	3	1	0
5x43	5x461	ffa3_on	4.24	0	1	3	1	2
5x43	Lig	Shared	4.78	10.07	1	3	1	0
5x44	6x55	Shared	4.39	7.32	0	0	2	1
6x51	6x52	ffa3_on	3.49	0	1	3	1	2
6x51	6x55	ffa3_on	10.89	0	1	3	1	1
6x51	7x37	Shared	3.79	6.31	1	3	1	2
6x51	7x38	ffa3_on	4.69	0	1	3	1	2
6x51	Lig	Shared	7.92	15.31	1	3	1	0
6x55	Lig	Shared	8.69	12.21	1	3	1	0
7x34	Lig	Shared	13.68	5.77	1	3	1	0
5x40	6x58	ffa3_on	1.5	0	1	3	1	2
3x30	4x57	ffa3_on_allo	0	9.78	0	0	2	1
3x32	3x33	ffa3_on_allo	0	5.36	0	0	2	1
3x36	3x37	ffa3_on_allo	0	3.63	0	0	2	1
3x37	Lig	ffa3_on_allo	0	6.96	1	3	1	0
4x56	5x461	ffa3_on_allo	0	5.14	0	0	2	2
4x57	Lig	ffa3_on_allo	0	3.77	0	0	1	0
7x37	7x38	ffa3_on_allo	0	2.98	0	0	2	2
7x34	E3.P255	ffa3_on_allo	0	2.88	1	3	1	2
6x58	E3.P255	ffa3_on_allo	0	2.03	0	0	2	2

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Difference Members
	Id	Description
	ffa3_on_allo	8J20-FFA3-Valeric acid-AR420626-Gi1/&β;1/&γ;2
	ffa3_on	8J21-FFA3-Butyric acid-Gi1/&β;1/&γ;2

Network Difference
Value	ffa3_on_allo	ffa3_on
I_min	2.95	2.77
Number of Linked Nodes	250	257
Number of Specific Nodes	7 (2.80%)	14 (5.45%)
Number of Shared Nodes	243 (97.20%)	243 (94.55%)
Number of Links	280	285
Number of Specific Links	98 (35.00%)	103 (36.14%)
Number of Shared Links	182 (65.00%)	182 (63.86%)
Number of Hubs	33	35
Number of Specific Hubs	16 (48.48%)	18 (51.43%)
Number of Shared Hubs	17 (51.52%)	17 (48.57%)
Average % Shared Neighbours (Jaccard)	50.17
Average % Shared Neighbours (Otsuka)	60.37
Average % Shared Neighbours (Overlap Coefficient)	70.22
Average % Shared Cliques (k3-6)	78.66
Graphlets Similarity	0.598997

Paths Difference
Value	ffa3_on_allo	ffa3_on
Number Of Nodes in MetaPath	83	63
Specific Nodes in MetaPath	47 (56.63%)	27 (42.86%)
Shared Nodes in MetaPath	243 (97.20%)	243 (97.20%)
Number Of Links MetaPath	85	66
Specific Links in MetaPath	65 (76.47%)	46 (69.70%)
Shared Links in MetaPath	182 (65.00%)	182 (65.00%)
Number of Shortest Paths	36265	42254
Length Of Smallest Path	3	3
Average Path Length	11.7774	14.3576
Length of Longest Path	25	34
Minimum Path Strength	1.345	1.37
Average Path Strength	6.24705	5.74064
Maximum Path Strength	23.17	20.845
Minimum Path Correlation	0.7	0.7
Average Path Correlation	0.923973	0.930241
Maximum Path Correlation	0.99	1
Minimum % Of Corr. Nodes	4.54545	3.44828
Average % Of Corr. Nodes	50.7827	48.5682
Maximum % Of Corr. Nodes	100	100
Minimum Path Hubs %	0	0
Average Path Hubs %	42.6741	41.5795
Maximum Path Hubs %	100	100

Details about the values in these tables can be found in the corresponding documentation page .

You can download a compressed (zip) file with structure(s), 3D outputs (as PyMol and VMD scripts) and numerical data files (as csv and plain text files).

Download ffa3_on_ortoallo.zip<

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