psnGPCR

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Orange: nodes, hubs and links specific of ffa4_on_allo network

Green: nodes, hubs and links shared by both networks

Purple: nodes, hubs and links specific of ffa4_on network

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Owner: the name of the network the link belong to or "Shared" if the corresponding link is present in both networks.

Strength: the interaction strength between the two nodes or 0 if the link is not present.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Owner	ffa4_on_allo Int. Strength	ffa4_on Int. Strength	ffa4_on_allo Hub1?	ffa4_on Hub1?	ffa4_on_allo Hub2?	ffa4_on Hub2?	ConSurf1	ConSurf2
1	E3.Q294	NT.R22	ffa4_on_allo	7.01	0	No	No	No	No	1	5
2	E3.Q294	NT.T23	ffa4_on_allo	7.09	0	No	No	No	No	1	8
3	7x31	NT.F25	ffa4_on_allo	4.33	0	No	No	Yes	Yes	4	5
4	4x65	NT.F27	ffa4_on_allo	7.5	0	Yes	No	Yes	No	5	5
5	E2x52	NT.F27	ffa4_on_allo	6.09	0	Yes	No	Yes	No	5	5
6	3x29	NT.F28	ffa4_on_allo	7.5	0	Yes	Yes	Yes	No	5	8
7	E2.I193	NT.S29	ffa4_on_allo	6.19	0	No	No	No	No	4	9
8	E2.R183	NT.V31	ffa4_on_allo	6.54	0	No	No	No	No	3	6
9	1x28	E1.E102	ffa4_on_allo	19.77	0	No	No	No	No	0	4
10	1x31	1x35	ffa4_on_allo	5.3	0	No	No	No	Yes	4	5
11	1x47	2x54	ffa4_on_allo	4.28	0	No	No	No	No	5	6
12	1x56	1x60	ffa4_on_allo	3.64	0	No	No	Yes	No	7	6
13	1x59	I1.R71	ffa4_on_allo	8.53	0	No	No	No	No	6	7
14	2x40	I1.R69	ffa4_on_allo	4.15	0	No	No	No	No	8	7
15	4x39	I1.R69	ffa4_on_allo	5.33	0	No	No	No	No	3	7
16	2x41	2x43	ffa4_on_allo	5.12	0	No	No	No	No	5	8
17	2x46	2x50	ffa4_on_allo	4.07	0	Yes	No	Yes	No	9	9
18	2x46	7x53	ffa4_on_allo	4.69	0	Yes	No	Yes	No	9	9
19	2x48	4x50	ffa4_on_allo	3.92	0	No	No	Yes	Yes	5	9
20	2x48	Alloh124	ffa4_on_allo	7.65	0	No	No	Yes	No	5	0
21	2x51	Alloh124	ffa4_on_allo	4.17	0	No	No	Yes	No	7	0
22	2x53	7x41	ffa4_on_allo	5.19	0	Yes	No	No	No	7	8
23	2x59	E1x52	ffa4_on_allo	4.15	0	No	No	Yes	No	5	6
24	2x60	3x28	ffa4_on_allo	4.47	0	No	No	No	No	6	6
25	2x61	2x65	ffa4_on_allo	4.56	0	Yes	No	No	No	6	5
26	3x24	E1x50	ffa4_on_allo	3.89	0	No	No	Yes	Yes	5	9
27	E1x50	E2.V179	ffa4_on_allo	3.68	0	Yes	Yes	Yes	No	9	5
28	3x25	4x65	ffa4_on_allo	6.98	0	No	No	Yes	No	9	5
29	3x27	3x31	ffa4_on_allo	4.47	0	No	No	No	No	5	4
30	3x29	3x32	ffa4_on_allo	7.46	0	Yes	Yes	Yes	No	5	7
31	3x29	4x61	ffa4_on_allo	7.31	0	Yes	Yes	Yes	No	5	5
32	3x32	7x42	ffa4_on_allo	3.73	0	Yes	No	Yes	No	7	7
33	3x33	5x43	ffa4_on_allo	3.89	0	Yes	No	Yes	No	5	5
34	3x34	4x53	ffa4_on_allo	4.5	0	No	No	No	No	5	8
35	3x36	6x48	ffa4_on_allo	4.22	0	No	No	Yes	No	7	9
36	3x37	5x43	ffa4_on_allo	5.28	0	No	No	Yes	No	6	5
37	3x41	5x461	ffa4_on_allo	8.24	0	No	No	Yes	No	6	6
38	3x43	6x45	ffa4_on_allo	3.65	0	No	No	Yes	Yes	8	9
39	3x46	7x53	ffa4_on_allo	3.79	0	No	No	Yes	No	8	9
40	3x55	5x64	ffa4_on_allo	7.68	0	No	No	No	No	6	5
41	4x50	Alloh124	ffa4_on_allo	4.11	0	Yes	Yes	Yes	No	9	0
42	4x60	E2.W198	ffa4_on_allo	5.4	0	No	No	Yes	Yes	8	7
43	4x61	E2x52	ffa4_on_allo	5.54	0	Yes	No	Yes	No	5	5
44	4x61	Lig	ffa4_on_allo	3.84	0	Yes	No	Yes	Yes	5	0
45	4x64	E2.R178	ffa4_on_allo	7.48	0	Yes	No	No	No	5	4
46	4x65	E2x50	ffa4_on_allo	5.59	0	Yes	No	Yes	No	5	9
47	E2.V179	E2x50	ffa4_on_allo	5.12	0	Yes	No	Yes	No	5	9
48	E2x52	Lig	ffa4_on_allo	3.84	0	Yes	No	Yes	Yes	5	0
49	5x36	E2.I201	ffa4_on_allo	4.1	0	Yes	Yes	Yes	No	5	4
50	E2.I201	E3.N291	ffa4_on_allo	7.08	0	Yes	No	No	No	4	2
51	E2.I201	E3.F292	ffa4_on_allo	3.77	0	Yes	No	No	No	4	1
52	5x36	E3.N291	ffa4_on_allo	6.57	0	Yes	Yes	No	No	5	2
53	5x37	E3.F292	ffa4_on_allo	3.77	0	No	No	No	No	4	1
54	5x42	5x46	ffa4_on_allo	6.01	0	No	No	No	No	4	4
55	5x461	Lig	ffa4_on_allo	3.81	0	Yes	No	Yes	Yes	6	0
56	5x57	5x58	ffa4_on_allo	6.36	0	No	No	Yes	Yes	5	9
57	5x66	6x31	ffa4_on_allo	9.68	0	No	No	No	No	5	7
58	5x71	I3.L245	ffa4_on_allo	3.64	0	No	No	No	No	3	3
59	6x21	6x25	ffa4_on_allo	4.1	0	No	No	No	No	0	3
60	6x22	6x23	ffa4_on_allo	4.18	0	No	No	No	No	5	2
61	6x24	6x28	ffa4_on_allo	4.33	0	No	No	No	No	2	4
62	6x29	6x30	ffa4_on_allo	15.36	0	No	No	No	No	5	6
63	6x32	6x33	ffa4_on_allo	9.62	0	No	No	No	No	6	8
64	6x48	7x41	ffa4_on_allo	3.64	0	Yes	No	No	No	9	8
65	6x48	Lig	ffa4_on_allo	7.1	0	Yes	No	Yes	Yes	9	0
66	6x52	Lig	ffa4_on_allo	4.94	0	No	No	Yes	Yes	7	0
67	6x58	7x34	ffa4_on_allo	3.77	0	No	No	Yes	Yes	5	4
68	6x61	E3.I298	ffa4_on_allo	5.49	0	No	No	Yes	No	4	0
69	E3.I298	E3.L296	ffa4_on_allo	5.71	0	Yes	No	No	No	0	0
70	7x55	8x49	ffa4_on_allo	3.72	0	No	No	No	No	5	8
71	1x55	Alloh124	ffa4_on_allo	3.59	0	No	No	Yes	No	4	0
72	3x49	3x50	ffa4_on_allo	3.49	0	No	Yes	Yes	No	8	9
73	2x44	Alloh124	ffa4_on_allo	3.33	0	No	No	Yes	No	5	0
74	5x74	I3.S244	ffa4_on_allo	3.23	0	No	No	No	No	2	5
75	6x36	8x49	ffa4_on_allo	3.2	0	No	No	No	No	7	8
76	3x53	I2x50	ffa4_on_allo	3.17	0	No	No	No	No	8	8
77	E2.I197	E2.V180	ffa4_on_allo	3.07	0	No	No	No	No	4	4
78	6x51	6x54	ffa4_on_allo	3.04	0	No	No	No	No	6	5
79	1x28	NT.G33	ffa4_on_allo	3	0	No	No	No	No	0	3
80	3x52	I2x50	ffa4_on_allo	2.98	0	No	No	No	No	4	8
81	1x58	Alloh124	ffa4_on_allo	2.85	0	No	No	Yes	No	1	0
82	6x53	6x56	ffa4_on_allo	2.85	0	No	No	No	No	5	6
83	6x60	E3.L296	ffa4_on_allo	2.85	0	No	No	No	No	4	0
84	3x48	3x51	ffa4_on_allo	2.83	0	No	No	Yes	Yes	5	8
85	2x40	4x42	ffa4_on_allo	2.77	0	No	No	No	Yes	8	6
86	2x42	4x46	ffa4_on_allo	2.77	0	No	No	No	No	7	7
87	4x56	5x43	ffa4_on_allo	2.77	0	No	No	Yes	No	5	5
88	6x41	7x52	ffa4_on_allo	2.77	0	No	No	Yes	Yes	8	8
89	5x71	I3.S244	ffa4_on_allo	2.64	0	No	No	No	No	3	5
90	3x51	3x56	ffa4_on_allo	2.63	0	Yes	Yes	No	Yes	8	5
91	1x57	2x47	ffa4_on_allo	2.62	0	No	No	Yes	Yes	7	9
92	E1.E102	NT.D30	ffa4_on_allo	2.6	0	No	No	Yes	Yes	4	6
93	7x36	7x39	ffa4_on_allo	2.59	0	No	No	No	No	4	4
94	5x73	I3.Y247	ffa4_on_allo	2.5	0	No	No	Yes	Yes	4	4
95	2x42	4x42	ffa4_on_allo	2.43	0	No	No	No	Yes	7	6
96	3x30	4x59	ffa4_on_allo	2.34	0	No	No	No	No	5	5
97	5x69	6x30	ffa4_on_allo	2.34	0	No	Yes	No	No	4	6
98	6x35	6x39	ffa4_on_allo	2.14	0	No	No	No	No	7	5
99	1x59	1x60	ffa4_on_allo	2.13	0	No	No	Yes	No	6	6
100	5x34	5x35	ffa4_on_allo	2.03	0	No	Yes	No	No	3	3
101	1x49	1x52	ffa4_on_allo	1.96	0	No	No	No	No	9	6
102	4x51	4x54	ffa4_on_allo	1.95	0	No	No	No	No	4	3
103	6x49	6x50	ffa4_on_allo	1.78	0	No	No	No	No	7	9
104	2x56	3x31	ffa4_on_allo	1.7	0	No	No	No	No	6	4
105	3x45	4x49	ffa4_on_allo	1.62	0	No	No	No	No	7	7
106	5x41	5x45	ffa4_on_allo	1.59	0	No	No	No	No	4	5
107	5x44	5x45	ffa4_on_allo	1.59	0	No	No	No	No	6	5
108	1x31	1x32	ffa4_on_allo	1.58	0	No	No	No	No	4	5
109	1x36	1x37	ffa4_on_allo	1.57	0	No	No	No	No	6	4
110	6x25	6x28	ffa4_on_allo	1.55	0	No	No	No	No	3	4
111	3x54	3x55	ffa4_on_allo	1.54	0	No	No	No	No	8	6
112	5x61	5x65	ffa4_on_allo	1.52	0	No	No	No	No	8	8
113	1x41	1x45	ffa4_on_allo	1.49	0	No	No	No	No	4	5
114	5x52	5x53	ffa4_on_allo	1.49	0	No	No	No	No	2	6
115	7x32	NT.D30	ffa4_on_allo	1.47	0	No	No	Yes	Yes	2	6
116	E2.I191	E2.I193	ffa4_on_allo	1.47	0	No	No	No	No	4	4
117	7x33	E3.I298	ffa4_on_allo	1.43	0	No	No	Yes	No	5	0
118	1x60	I1.A73	ffa4_on_allo	1.38	0	Yes	No	No	No	6	0
119	E1x51	E1x52	ffa4_on_allo	1.38	0	No	No	Yes	No	4	6
120	5x72	I3.L245	ffa4_on_allo	1.38	0	No	Yes	No	No	5	3
121	5x68	5x69	ffa4_on_allo	1.32	0	No	No	No	Yes	6	4
122	1x33	2x65	ffa4_on_allo	1.3	0	No	No	No	No	3	5
123	1x42	7x42	ffa4_on_allo	1.26	0	No	No	Yes	No	7	7
124	8x49	8x50	ffa4_on_allo	1.21	0	No	No	No	No	8	6
125	E2x51	NT.R24	Shared	6.47	6.1	No	No	No	Yes	4	5
126	E2.I197	NT.R24	Shared	6.26	3.04143	No	No	No	Yes	4	5
127	NT.F25	NT.P26	Shared	5.78	4.53714	Yes	Yes	No	No	5	5
128	NT.F25	NT.F27	Shared	7.5	6.73714	Yes	Yes	Yes	No	5	5
129	6x58	NT.F25	Shared	5.02	4.12571	No	No	Yes	Yes	5	5
130	7x34	NT.F25	Shared	9.65	3.82714	Yes	Yes	Yes	Yes	4	5
131	3x29	NT.F27	Shared	9.65	3.67286	Yes	Yes	Yes	No	5	5
132	2x60	NT.F28	Shared	13.11	7.30571	No	No	Yes	No	6	8
133	7x34	NT.F28	Shared	5.36	4.74714	Yes	Yes	Yes	No	4	8
134	7x38	NT.F28	Shared	7.87	4.68286	No	No	Yes	No	5	8
135	2x64	NT.D30	Shared	14.29	4.25429	No	No	Yes	Yes	4	6
136	7x31	NT.D30	Shared	4.83	4.37	No	No	Yes	Yes	4	6
137	1x27	NT.D34	Shared	21.43	3.06143	No	Yes	No	No	0	3
138	1x35	2x64	Shared	12.79	9.63857	No	Yes	No	No	5	4
139	1x35	7x35	Shared	11.66	11.8286	No	Yes	Yes	Yes	5	4
140	1x36	2x61	Shared	5.9	4.21143	No	No	Yes	No	6	6
141	1x36	2x65	Shared	18.19	5.54429	No	No	No	No	6	5
142	1x39	2x57	Shared	8.56	5.91143	No	Yes	Yes	Yes	6	7
143	1x39	7x35	Shared	6.09	4.34857	No	Yes	Yes	Yes	6	4
144	1x43	1x47	Shared	4.87	1.39143	No	No	No	No	6	5
145	1x43	2x54	Shared	3.77	4.12714	No	No	No	No	6	6
146	1x43	2x57	Shared	6.28	6.99571	No	No	Yes	Yes	6	7
147	1x46	2x54	Shared	9.29	8.40429	No	No	No	No	8	6
148	1x46	7x46	Shared	4.89	5.12286	No	No	No	No	8	9
149	1x49	7x50	Shared	4.06	0.87	No	No	No	No	9	9
150	1x50	2x47	Shared	3.62	4.83143	Yes	Yes	Yes	Yes	9	9
151	1x50	2x50	Shared	12.12	10.77	Yes	Yes	Yes	No	9	9
152	1x50	2x51	Shared	4.12	5.10143	Yes	Yes	No	No	9	7
153	1x50	7x50	Shared	14.66	7.68143	Yes	Yes	No	No	9	9
154	1x53	2x47	Shared	8.32	6.14143	No	No	Yes	Yes	8	9
155	1x54	2x47	Shared	7.31	3.65286	No	No	Yes	Yes	6	9
156	1x60	8x47	Shared	3.64	1.21429	Yes	No	No	No	6	8
157	2x43	2x47	Shared	5.24	5.24143	No	No	Yes	Yes	8	9
158	2x45	3x42	Shared	10.24	7.93714	No	Yes	No	No	9	8
159	2x45	4x46	Shared	9.61	5.68857	No	Yes	No	No	9	7
160	2x45	4x50	Shared	6.78	10.4929	No	Yes	Yes	Yes	9	9
161	2x46	3x42	Shared	4.42	5.89714	Yes	No	No	No	9	8
162	2x46	3x43	Shared	5.54	4.54857	Yes	No	No	No	9	8
163	2x46	7x49	Shared	9.61	3.92286	Yes	No	No	No	9	9
164	2x47	7x54	Shared	7.25	2.93429	Yes	Yes	No	Yes	9	7
165	2x50	7x46	Shared	8.83	4.62571	Yes	No	No	No	9	9
166	2x50	7x49	Shared	12.12	7.11857	Yes	No	No	No	9	9
167	2x52	2x55	Shared	6.01	1.07143	No	No	No	No	6	4
168	2x52	3x35	Shared	4.5	6.00571	No	No	No	No	6	8
169	2x53	3x35	Shared	9.25	6.98286	Yes	No	No	No	7	8
170	2x53	7x42	Shared	7.5	8.88143	Yes	No	Yes	No	7	7
171	2x53	Lig	Shared	4.22	3.44571	Yes	No	Yes	Yes	7	0
172	2x57	2x58	Shared	5.08	4.11429	Yes	Yes	No	No	7	9
173	2x57	7x42	Shared	7.54	7.71571	Yes	Yes	Yes	No	7	7
174	2x59	3x28	Shared	8.3	7.51286	No	No	No	No	5	6
175	2x63	E1x50	Shared	7.36	8.23143	No	No	Yes	Yes	5	9
176	2x64	7x35	Shared	24.59	18.6286	No	No	Yes	Yes	4	4
177	2x66	E1x51	Shared	10.32	3.37	No	No	No	No	4	4
178	E1x50	E1x52	Shared	11.39	6.34571	Yes	Yes	Yes	No	9	6
179	3x25	E1x50	Shared	11.75	7.64857	No	No	Yes	Yes	9	9
180	E1x50	E2x50	Shared	11.75	13.4314	Yes	Yes	Yes	No	9	9
181	3x24	E1x52	Shared	4.73	3.15286	No	No	Yes	No	5	6
182	3x21	3x22	Shared	4.06	4.06	No	No	No	No	8	3
183	3x25	E2x50	Shared	7.28	5.72	No	No	Yes	No	9	9
184	3x29	4x65	Shared	18.22	13.1643	Yes	Yes	Yes	No	5	5
185	3x29	Lig	Shared	11.81	3.95857	Yes	Yes	Yes	Yes	5	0
186	3x30	4x62	Shared	9.41	7.87143	No	No	No	No	5	4
187	3x32	Lig	Shared	9.79	6.88143	Yes	No	Yes	Yes	7	0
188	3x33	4x61	Shared	5.9	5.89428	Yes	No	Yes	No	5	5
189	3x33	Lig	Shared	11.23	4.69	Yes	No	Yes	Yes	5	0
190	3x34	4x50	Shared	5.69	2.76714	No	No	Yes	Yes	5	9
191	3x37	5x461	Shared	8.94	6.17286	No	No	Yes	No	6	6
192	3x38	4x50	Shared	14.71	13.8343	No	No	Yes	Yes	7	9
193	3x38	4x53	Shared	6.46	4.15571	No	No	No	No	7	8
194	3x39	6x48	Shared	4.85	3.12	No	No	Yes	No	9	9
195	3x40	6x45	Shared	5.02	4.12429	No	No	Yes	Yes	8	9
196	3x40	6x48	Shared	16.44	12.0786	No	No	Yes	No	8	9
197	3x43	7x53	Shared	8.21	7.36857	No	No	Yes	No	8	9
198	3x44	5x50	Shared	3.74	2.40429	No	No	No	No	7	9
199	3x46	3x50	Shared	6.54	4.85714	No	No	Yes	No	8	9
200	3x47	5x54	Shared	9.29	5.97143	No	No	No	No	8	8
201	3x47	5x57	Shared	4.89	4.89	No	No	No	No	8	5
202	3x47	5x58	Shared	12.72	8.54	No	No	Yes	Yes	8	9
203	3x50	5x58	Shared	5.14	5.88	Yes	No	Yes	Yes	9	9
204	3x50	7x53	Shared	6.17	4.55571	Yes	No	Yes	No	9	9
205	3x51	5x57	Shared	6.13	6.35286	Yes	Yes	No	No	8	5
206	3x51	5x60	Shared	5.76	5.96571	Yes	Yes	No	Yes	8	5
207	3x51	5x61	Shared	4.37	3.12143	Yes	Yes	No	No	8	8
208	3x52	3x56	Shared	6.92	2.17286	No	No	No	Yes	4	5
209	3x55	3x56	Shared	12.45	1.18571	No	No	No	Yes	6	5
210	4x60	5x39	Shared	12.16	9.84286	No	No	Yes	Yes	8	6
211	4x63	4x64	Shared	7.87	8.24	No	No	Yes	No	4	5
212	4x64	E2.W198	Shared	11.02	3.00571	Yes	No	Yes	Yes	5	7
213	4x64	E2.P199	Shared	7.22	9.49286	Yes	No	No	No	5	6
214	4x65	E2x52	Shared	8.53	13.0486	Yes	No	Yes	No	5	5
215	E2.I197	E2.R178	Shared	7.52	1.96857	No	No	No	No	4	4
216	E2.Q182	E2.R183	Shared	8.18	1.00143	No	No	No	No	2	3
217	E2.I193	E2.Q182	Shared	8.23	3.72571	No	No	No	No	4	2
218	E2.W198	E2x52	Shared	10.25	9.11	Yes	Yes	Yes	No	7	5
219	5x36	E2.W198	Shared	11.99	18.07	Yes	Yes	Yes	Yes	5	7
220	5x39	E2.W198	Shared	14.99	5.22	Yes	Yes	Yes	Yes	6	7
221	5x34	E2.T200	Shared	5.25	0.5	No	Yes	No	No	3	3
222	5x35	5x38	Shared	3.71	0.795714	No	No	No	No	3	4
223	5x36	6x59	Shared	5.3	3.97714	Yes	Yes	No	No	5	4
224	5x36	Lig	Shared	4.59	5.18571	Yes	Yes	Yes	Yes	5	0
225	5x39	5x40	Shared	7.82	4.78857	Yes	Yes	Yes	Yes	6	5
226	5x39	5x43	Shared	11.02	13.1729	Yes	Yes	Yes	No	6	5
227	5x40	6x55	Shared	5.6	3.4	Yes	Yes	No	No	5	5
228	5x40	6x59	Shared	16.29	9.30714	Yes	Yes	No	No	5	4
229	5x40	Lig	Shared	7.52	11.1271	Yes	Yes	Yes	Yes	5	0
230	5x43	5x461	Shared	9.67	8.97714	Yes	No	Yes	No	5	6
231	5x43	Lig	Shared	9.28	6.25571	Yes	No	Yes	Yes	5	0
232	5x44	6x52	Shared	4.61	4.16857	No	No	No	No	6	7
233	5x47	5x48	Shared	3.65	2.26286	No	Yes	No	No	8	4
234	5x47	6x52	Shared	18.84	12.0229	No	Yes	No	No	8	7
235	5x51	6x45	Shared	4.52	3.66	No	No	Yes	Yes	6	9
236	5x54	6x45	Shared	7.54	3.94857	No	No	Yes	Yes	8	9
237	5x58	6x41	Shared	9.38	5.69429	Yes	Yes	No	No	9	8
238	5x58	6x42	Shared	5.99	5.30286	Yes	Yes	No	No	9	8
239	5x62	5x66	Shared	5.64	1.61143	No	No	No	No	6	5
240	5x62	6x35	Shared	7.31	2.96	No	No	No	No	6	7
241	5x62	6x38	Shared	9.69	5.33857	No	No	No	No	6	8
242	5x65	6x34	Shared	4.42	3.99857	No	No	No	No	8	8
243	5x70	5x74	Shared	4.55	0.434286	No	No	No	No	5	2
244	5x73	6x24	Shared	11.34	2.83286	No	No	No	No	4	2
245	6x27	I3.Y247	Shared	3.79	3.42571	No	No	Yes	Yes	5	4
246	6x20	6x23	Shared	12.55	2.38857	No	No	No	No	0	2
247	6x32	6x36	Shared	11.76	4.58143	No	No	No	No	6	7
248	6x33	6x36	Shared	6.4	1.67571	No	No	No	No	8	7
249	6x39	6x43	Shared	13.11	5.43143	No	No	No	No	5	5
250	6x44	7x52	Shared	4.5	2.78571	No	No	Yes	Yes	6	8
251	6x45	6x46	Shared	11.79	9.49143	Yes	Yes	No	No	9	6
252	6x47	7x40	Shared	11.2	5.15429	Yes	Yes	No	No	8	7
253	6x47	7x45	Shared	7.01	12.0214	Yes	Yes	No	No	8	9
254	6x47	7x48	Shared	4.24	3.63429	Yes	Yes	No	No	8	6
255	6x48	7x45	Shared	19.21	19.8557	Yes	No	No	No	9	9
256	6x50	7x40	Shared	8.67	6.81	No	No	No	No	9	7
257	6x51	7x41	Shared	12.16	4.99429	No	No	No	No	6	8
258	6x51	Lig	Shared	18.79	8.04714	No	No	Yes	Yes	6	0
259	6x54	7x37	Shared	7.93	5.21429	No	No	No	No	5	6
260	6x55	Lig	Shared	15.82	8.3	No	No	Yes	Yes	5	0
261	6x58	Lig	Shared	9.89	6.78	No	No	Yes	Yes	5	0
262	6x61	E3.L296	Shared	13.31	1.52143	No	No	No	No	4	0
263	7x34	7x38	Shared	5.24	5.05429	Yes	Yes	No	No	4	5
264	7x35	7x36	Shared	10.02	5.58286	Yes	Yes	No	No	4	4
265	7x38	7x42	Shared	3.93	4.67857	No	No	Yes	No	5	7
266	7x54	8x47	Shared	6.87	1.56857	No	Yes	No	No	7	8
267	NT.P26	NT.S29	Shared	3.56	3.30571	No	No	No	No	5	9
268	3x22	E2.V179	Shared	3.53	1.76857	No	No	Yes	No	3	5
269	5x49	5x50	Shared	3.53	4.03571	No	No	No	No	5	9
270	1x48	1x49	Shared	3.42	2.19857	No	No	No	No	4	9
271	3x40	5x50	Shared	3.39	3.39	No	No	No	No	8	9
272	5x34	E2.I201	Shared	3.39	0.484286	No	Yes	Yes	No	3	4
273	3x33	4x57	Shared	3.36	3.12	Yes	No	No	No	5	7
274	6x23	I3.Y247	Shared	3.27	4.2	No	No	Yes	Yes	2	4
275	E1x49	E2.I191	Shared	3.25	0.925714	No	No	No	No	5	4
276	2x56	3x32	Shared	3.22	2.76	No	No	Yes	No	6	7
277	5x55	6x42	Shared	3.04	3.25857	No	No	No	No	5	8
278	1x40	2x61	Shared	2.98	1.06429	No	No	Yes	No	4	6
279	1x47	1x51	Shared	2.98	1.49	No	No	No	No	5	3
280	6x461	6x47	Shared	2.92	1.25143	No	No	Yes	Yes	5	8
281	4x42	I2x57	Shared	2.88	1.23571	No	Yes	No	No	6	6
282	3x41	4x49	Shared	2.85	2.44571	No	No	No	No	6	7
283	4x45	4x49	Shared	2.85	1.02	No	No	No	No	5	7
284	6x57	6x60	Shared	2.85	1.83429	No	No	No	No	5	4
285	6x57	E3.I298	Shared	2.85	2.03714	No	No	Yes	No	5	0
286	1x27	1x30	Shared	2.77	1.97571	No	Yes	No	No	0	0
287	1x39	2x61	Shared	2.77	4.15286	No	Yes	Yes	No	6	6
288	6x34	6x38	Shared	2.77	2.76714	No	No	No	No	8	8
289	6x40	7x52	Shared	2.77	1.97714	No	No	Yes	Yes	6	8
290	E3.D295	E3.K293	Shared	2.77	0.592857	No	No	No	No	0	1
291	7x48	7x52	Shared	2.77	4.15143	No	No	Yes	Yes	6	8
292	3x30	4x57	Shared	2.67	2.66857	No	No	No	No	5	7
293	5x69	6x28	Shared	2.64	1.13	No	Yes	No	No	4	4
294	7x30	7x32	Shared	2.47	2.29571	No	No	No	No	4	2
295	1x38	7x36	Shared	2.45	2.62571	No	No	No	No	6	4
296	4x52	5x46	Shared	2.34	5.19143	No	No	No	No	4	4
297	5x72	I3.Y247	Shared	2.34	3.51714	No	Yes	Yes	Yes	5	4
298	4x52	5x461	Shared	2.33	7.80571	No	No	Yes	No	4	6
299	3x26	E2.R178	Shared	2.26	2.25714	No	No	No	No	7	4
300	4x38	4x41	Shared	1.95	0.278571	No	No	No	No	7	5
301	E2.P181	E2.V180	Shared	1.77	2.52429	No	No	No	No	2	4
302	NT.G33	NT.K32	Shared	1.74	0.497143	No	No	No	Yes	3	3
303	1x46	7x47	Shared	1.71	1.71	No	No	No	No	8	6
304	1x45	7x47	Shared	1.7	1.94143	No	No	No	No	5	6
305	2x49	3x38	Shared	1.7	3.14857	No	No	No	No	8	7
306	3x44	5x53	Shared	1.7	1.69571	No	No	No	No	7	6
307	1x42	7x43	Shared	1.62	1.15714	No	No	No	No	7	5
308	E2.S192	E2.V179	Shared	1.62	1.84714	No	No	Yes	No	3	5
309	3x34	4x54	Shared	1.58	1.58	No	No	No	No	5	3
310	I2x52	I2x53	Shared	1.5	0.214286	No	No	No	No	5	6
311	5x44	6x56	Shared	1.49	1.70286	No	No	No	No	6	6
312	5x52	5x56	Shared	1.43	3.46714	No	No	No	No	2	4
313	7x30	7x33	Shared	1.14	4.06857	No	No	No	No	4	5
314	1x32	2x65	ffa4_on	0	5.18857	No	No	No	No	5	5
315	1x35	7x36	ffa4_on	0	7.01	No	Yes	No	No	5	4
316	2x42	3x49	ffa4_on	0	4.54429	No	No	No	Yes	7	8
317	2x54	7x46	ffa4_on	0	4.86714	No	No	No	No	6	9
318	3x28	3x29	ffa4_on	0	3.65286	No	No	Yes	Yes	6	5
319	3x36	Lig	ffa4_on	0	3.44	No	No	Yes	Yes	7	0
320	3x37	4x53	ffa4_on	0	3.72571	No	No	No	No	6	8
321	3x48	5x53	ffa4_on	0	3.40571	No	No	No	No	5	6
322	3x49	4x42	ffa4_on	0	4.32	No	Yes	No	Yes	8	6
323	4x61	4x65	ffa4_on	0	3.30571	Yes	No	Yes	No	5	5
324	4x61	5x39	ffa4_on	0	5.69429	Yes	No	Yes	Yes	5	6
325	E2	E2	ffa4_on	0	4.11857	No	No	No	No	0	0
326	5x36	E2	ffa4_on	0	4.67286	Yes	Yes	No	No	5	0
327	5x32	5x34	ffa4_on	0	3.74714	No	No	No	Yes	0	3
328	5x47	6x45	ffa4_on	0	4.13714	No	Yes	Yes	Yes	8	9
329	5x47	6x49	ffa4_on	0	3.58286	No	Yes	No	No	8	7
330	5x54	5x58	ffa4_on	0	3.28286	No	No	Yes	Yes	8	9
331	5x58	6x38	ffa4_on	0	6.36429	Yes	Yes	No	No	9	8
332	5x66	5x70	ffa4_on	0	3.48857	No	No	No	No	5	5
333	5x69	6x27	ffa4_on	0	5.04429	No	Yes	No	No	4	5
334	6x41	7x53	ffa4_on	0	5.19	No	No	Yes	No	8	9
335	7x30	7x31	ffa4_on	0	3.66571	No	No	No	No	4	4
336	7x34	Lig	ffa4_on	0	3.79	Yes	Yes	Yes	Yes	4	0
337	E2.I193	NT.R24	ffa4_on	0	4.47286	No	No	No	Yes	4	5
338	6x61	NT.F25	ffa4_on	0	4.01429	No	No	Yes	Yes	4	5
339	E3.I298	NT.F25	ffa4_on	0	4.84429	Yes	No	Yes	Yes	0	5
340	E2.I193	NT.P26	ffa4_on	0	3.38571	No	No	No	No	4	5
341	7x34	NT.F27	ffa4_on	0	5.05286	Yes	Yes	Yes	No	4	5
342	NT.D30	NT.K32	ffa4_on	0	4.14857	Yes	Yes	No	Yes	6	3
343	1x28	NT.K32	ffa4_on	0	5.12857	No	No	No	Yes	0	3
344	1x27	1x31	ffa4_on	0	6.42857	No	Yes	No	No	0	4
345	E2.W198	Lig	ffa4_on	0	4.22429	Yes	Yes	Yes	Yes	7	0
346	5x36	6x62	ffa4_on	0	6.57143	Yes	Yes	No	No	5	0
347	6x23	6x26	ffa4_on	0	5.96286	No	No	No	Yes	2	4
348	7x45	7x49	ffa4_on	0	4.86429	No	No	No	No	9	9
349	5x69	I3.Y247	ffa4_on	0	3.96857	No	Yes	Yes	Yes	4	4
350	5x69	6x31	ffa4_on	0	7.99714	No	Yes	No	No	4	7
351	6x64	E3.D295	ffa4_on	0	3.55571	No	Yes	No	No	0	0
352	1x57	2x44	ffa4_on	0	3.19286	No	No	No	No	7	5
353	3x54	5x61	ffa4_on	0	3.15429	No	No	No	No	8	8
354	4x59	4x60	ffa4_on	0	3.04857	No	No	No	No	5	8
355	1x28	E1	ffa4_on	0	2.99	No	No	No	No	0	0
356	E2.V180	NT.R24	ffa4_on	0	2.99	No	No	No	Yes	4	5
357	1x54	2x44	ffa4_on	0	2.96429	No	No	No	No	6	5
358	6x64	I3.D295	ffa4_on	0	2.96286	No	Yes	No	No	0	0
359	5x45	5x48	ffa4_on	0	2.94714	No	No	No	No	5	4
360	3x28	E1x50	ffa4_on	0	2.93	No	No	Yes	Yes	6	9
361	E1.E102	E2.I191	ffa4_on	0	2.92857	No	No	No	No	4	4
362	5x33	5x34	ffa4_on	0	2.90571	No	No	No	Yes	0	3
363	4x52	4x56	ffa4_on	0	2.85857	No	No	No	No	4	5
364	7x31	NT	ffa4_on	0	2.80857	No	No	No	No	4	0
365	1x56	7x54	ffa4_on	0	2.74714	No	No	No	Yes	7	7
366	5x60	5x63	ffa4_on	0	2.71286	No	Yes	No	No	5	4
367	6x20	6x21	ffa4_on	0	2.67	No	No	No	No	0	0
368	6x24	6x27	ffa4_on	0	2.66143	No	No	No	No	2	5
369	3x49	I1.T74	ffa4_on	0	2.62143	No	Yes	No	No	8	0
370	6x64	E3.V297	ffa4_on	0	2.60143	No	Yes	No	No	0	0
371	6x54	7x34	ffa4_on	0	2.59143	No	No	Yes	Yes	5	4
372	1x27	NT	ffa4_on	0	2.52143	No	Yes	No	No	0	0
373	5x68	5x71	ffa4_on	0	2.44714	No	No	No	No	6	3
374	3x51	3x55	ffa4_on	0	2.38857	Yes	Yes	No	No	8	6
375	5x60	5x64	ffa4_on	0	2.28429	No	Yes	No	No	5	5
376	NT.R22	NT.R24	ffa4_on	0	2.28429	No	No	No	Yes	5	5
377	E2.R183	NT.T23	ffa4_on	0	2.21714	No	No	No	No	3	8
378	5x72	I3	ffa4_on	0	2.20714	No	Yes	No	No	5	0
379	4x39	4x43	ffa4_on	0	2.17286	No	No	No	No	3	3
380	E2.E190	E2.R183	ffa4_on	0	2.16	No	No	No	No	0	3
381	I3.D295	I3.V297	ffa4_on	0	2.08714	No	No	No	No	0	0
382	6x36	6x40	ffa4_on	0	2.08286	No	No	No	No	7	6
383	1x34	1x35	ffa4_on	0	2.03714	No	No	No	Yes	5	5
384	3x53	I2x51	ffa4_on	0	1.96286	No	No	No	No	8	6
385	2x42	3x46	ffa4_on	0	1.91571	No	No	No	No	7	8
386	2x52	3x31	ffa4_on	0	1.91571	No	No	No	No	6	4
387	6x31	6x35	ffa4_on	0	1.87714	No	No	No	No	7	7
388	5x37	6x59	ffa4_on	0	1.83571	No	No	No	No	4	4
389	2x45	4x49	ffa4_on	0	1.82143	No	Yes	No	No	9	7
390	6x37	7x55	ffa4_on	0	1.72	No	No	No	No	8	5
391	3x25	E2.V179	ffa4_on	0	1.71	No	No	Yes	No	9	5
392	1x55	1x59	ffa4_on	0	1.68143	No	No	No	No	4	6
393	5x33	5x37	ffa4_on	0	1.68	No	No	No	No	0	4
394	I3.I298	NT.F25	ffa4_on	0	1.61429	No	No	Yes	Yes	0	5
395	E1.E102	NT.K32	ffa4_on	0	1.54286	No	No	No	Yes	4	3
396	1x38	1x42	ffa4_on	0	1.53571	No	No	No	No	6	7
397	3x49	R:R:L77	ffa4_on	0	1.51429	No	Yes	No	No	8	0
398	1x56	7x56	ffa4_on	0	1.47429	No	No	No	No	7	7
399	E2.L184	E2.P185	ffa4_on	0	1.40857	No	No	No	No	0	0
400	I1.R70	I1.R71	ffa4_on	0	1.37143	No	No	No	No	7	7
401	6x25	6x29	ffa4_on	0	1.37143	No	No	No	No	3	5
402	3x56	I2x56	ffa4_on	0	1.36286	No	Yes	No	No	5	0
403	1x48	1x52	ffa4_on	0	1.35857	No	No	No	No	4	6
404	2x42	3x45	ffa4_on	0	1.35429	No	No	No	No	7	7
405	1x39	7x39	ffa4_on	0	1.35286	No	Yes	No	No	6	4
406	5x72	I3.A246	ffa4_on	0	1.35143	No	Yes	No	No	5	4
407	6x49	6x53	ffa4_on	0	1.32714	No	No	No	No	7	5
408	1x29	2x65	ffa4_on	0	1.30286	No	No	No	No	0	5
409	5x32	5x35	ffa4_on	0	1.3	No	No	No	No	0	3
410	3x23	3x27	ffa4_on	0	1.27714	No	No	No	No	2	5
411	6x37	6x41	ffa4_on	0	1.26429	No	No	No	No	8	8
412	5x33	E3.F292	ffa4_on	0	1.25571	No	No	No	No	0	1
413	4x39	4x42	ffa4_on	0	1.22	No	No	No	Yes	3	6
414	1x60	I1.R71	ffa4_on	0	1.21857	Yes	No	No	No	6	7
415	1x37	1x38	ffa4_on	0	1.13571	No	No	No	No	4	6
416	6x43	6x461	ffa4_on	0	1.09714	No	No	No	No	5	5
417	6x63	6x64	ffa4_on	0	1.06286	No	No	No	Yes	0	0
418	3x53	3x56	ffa4_on	0	1.05286	No	No	No	Yes	8	5
419	NT.D30	NT.V31	ffa4_on	0	1.04286	Yes	Yes	No	No	6	6
420	6x60	6x64	ffa4_on	0	1.03857	No	No	No	Yes	4	0
421	3x49	I1	ffa4_on	0	1.00857	No	Yes	No	No	8	0
422	3x56	I2x54	ffa4_on	0	0.988571	No	Yes	No	No	5	0
423	E1x49	E1x51	ffa4_on	0	0.902857	No	No	No	No	5	4
424	2x45	2x48	ffa4_on	0	0.898571	No	Yes	No	No	9	5
425	5x37	5x41	ffa4_on	0	0.88	No	No	No	No	4	4
426	2x41	3x49	ffa4_on	0	0.868571	No	No	No	Yes	5	8
427	E3.N291	NT.R22	ffa4_on	0	0.861429	No	No	No	No	2	5
428	7x51	7x52	ffa4_on	0	0.815714	No	No	Yes	Yes	7	8
429	4x50	4x51	ffa4_on	0	0.805714	Yes	Yes	No	No	9	4
430	6x61	E3	ffa4_on	0	0.784286	No	No	No	No	4	0
431	I1.R69	I1.R70	ffa4_on	0	0.761429	No	No	No	No	7	7
432	6x22	6x26	ffa4_on	0	0.754286	No	No	No	Yes	5	4
433	1x33	1x36	ffa4_on	0	0.72	No	No	No	No	3	6
434	1x51	1x55	ffa4_on	0	0.685714	No	No	No	No	3	4
435	7x54	8x48	ffa4_on	0	0.674286	No	Yes	No	No	7	5
436	6x26	6x30	ffa4_on	0	0.668571	No	Yes	No	No	4	6
437	3x56	I2x52	ffa4_on	0	0.644286	No	Yes	No	No	5	5
438	I1.G72	I1.R71	ffa4_on	0	0.642857	No	No	No	No	0	7
439	E2.L184	NT.V31	ffa4_on	0	0.638571	No	No	No	No	0	6
440	1x37	1x41	ffa4_on	0	0.631429	No	No	No	No	4	4
441	5x56	5x60	ffa4_on	0	0.622857	No	No	No	Yes	4	5
442	8x48	8x49	ffa4_on	0	0.597143	No	No	No	No	5	8
443	4x41	4x42	ffa4_on	0	0.592857	No	No	No	Yes	5	6
444	I1.A73	I1.G72	ffa4_on	0	0.557143	No	No	No	No	0	0
445	5x39	5x42	ffa4_on	0	0.53	Yes	Yes	No	No	6	4
446	5x71	5x72	ffa4_on	0	0.52	No	No	No	Yes	3	5
447	6x26	6x29	ffa4_on	0	0.501429	No	Yes	No	No	4	5
448	4x39	4x40	ffa4_on	0	0.457143	No	No	No	No	3	5
449	3x24	3x27	ffa4_on	0	0.45	No	No	No	No	5	5
450	I2x55	I2x56	ffa4_on	0	0.428571	No	No	No	No	0	0
451	1x58	1x59	ffa4_on	0	0.395714	No	No	No	No	1	6
452	1x60	2x40	ffa4_on	0	0.395714	Yes	No	No	No	6	8
453	E3.K293	E3.Q294	ffa4_on	0	0.387143	No	No	No	No	1	1
454	4x40	4x44	ffa4_on	0	0.374286	No	No	No	No	5	4
455	E2.E190	E2.Q189	ffa4_on	0	0.362857	No	No	No	No	0	0
456	E2.A187	E2.I191	ffa4_on	0	0.231429	No	No	No	No	0	4
457	5x55	5x59	ffa4_on	0	0.231429	No	No	No	No	5	3
458	5x63	5x67	ffa4_on	0	0.217143	No	No	No	No	4	4
459	4x45	4x48	ffa4_on	0	0.197143	No	No	No	No	5	2

Orange: nodes, hubs and links specific of ffa4_on_allo network

Green: nodes, hubs and links shared by both networks

Purple: nodes, hubs and links specific of ffa4_on network

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Owner: the name of the network the hub belong to or "Shared" if the corresponding hub is present in both networks.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub in the corresponding network.

Num Of Links: the number of links of the corresponding hub in the corresponding network.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Owner	ffa4_on_allo Avg Int. Strength	ffa4_on Avg Int. Strength	ffa4_on_allo Num Of Links	ffa4_on Num Of Links	ConSurf
1	NT.F27	ffa4_on_allo	7.685	5.15429	4	3	5
2	NT.F28	ffa4_on_allo	8.46	5.57857	4	3	8
3	1x60	ffa4_on_allo	2.6975	0.942857	4	3	6
4	2x46	ffa4_on_allo	5.666	4.78952	5	3	9
5	2x50	ffa4_on_allo	9.285	7.50476	4	3	9
6	2x53	ffa4_on_allo	6.54	6.43667	4	3	7
7	2x61	ffa4_on_allo	4.0525	3.14286	4	3	6
8	E1x52	ffa4_on_allo	5.4125	4.74929	4	2	6
9	3x32	ffa4_on_allo	6.05	4.82071	4	2	7
10	3x33	ffa4_on_allo	6.095	4.56809	4	3	5
11	3x50	ffa4_on_allo	5.335	5.09762	4	3	9
12	4x61	ffa4_on_allo	5.6475	4.96476	4	3	5
13	4x64	ffa4_on_allo	8.3975	6.91286	4	3	5
14	4x65	ffa4_on_allo	9.364	9.83952	5	3	5
15	E2.V179	ffa4_on_allo	3.4875	1.77524	4	3	5
16	E2x50	ffa4_on_allo	7.435	9.57571	4	2	9
17	E2x52	ffa4_on_allo	6.85	11.0793	5	2	5
18	E2.I201	ffa4_on_allo	4.585	0.484286	4	1	4
19	5x43	ffa4_on_allo	6.985	9.46857	6	3	5
20	5x461	ffa4_on_allo	6.598	7.65191	5	3	6
21	6x48	ffa4_on_allo	9.24333	11.6848	6	3	9
22	E3.I298	ffa4_on_allo	3.87	3.44071	4	2	0
23	7x42	ffa4_on_allo	4.792	7.09191	5	3	7
24	7x53	ffa4_on_allo	5.715	5.70476	4	3	9
25	Alloh124	ffa4_on_allo	4.28333	0	6	0	0
26	NT.F25	Shared	6.456	4.24286	5	7	5
27	NT.D30	Shared	5.7975	3.45393	4	4	6
28	1x50	Shared	8.63	7.09607	4	4	9
29	2x47	Shared	5.72667	4.56029	6	5	9
30	2x57	Shared	6.865	6.18429	4	4	7
31	E1x50	Shared	8.30333	7.71743	6	5	9
32	3x29	Shared	10.325	6.11214	6	4	5
33	3x51	Shared	4.344	4.45714	5	4	8
34	4x50	Shared	7.042	6.975	5	4	9
35	E2.W198	Shared	10.73	7.926	5	5	7
36	5x36	Shared	6.51	7.69543	5	5	5
37	5x39	Shared	11.4975	6.54143	4	6	6
38	5x40	Shared	9.3075	7.15571	4	4	5
39	5x58	Shared	7.918	5.84405	5	6	9
40	I3.Y247	Shared	2.975	3.77786	4	4	4
41	6x45	Shared	6.504	5.07229	5	5	9
42	6x47	Shared	6.3425	5.51536	4	4	8
43	7x34	Shared	6.005	4.17714	4	6	4
44	7x35	Shared	13.09	10.0971	4	4	4
45	7x52	Shared	3.2025	2.4325	4	4	8
46	Lig	Shared	8.43133	5.85582	15	13	0
47	1x27	ffa4_on	12.1	3.49679	2	4	0
48	1x35	ffa4_on	9.91667	7.62857	3	4	5
49	1x39	ffa4_on	5.80667	3.94143	3	4	6
50	2x45	ffa4_on	8.87667	5.36771	3	5	9
51	3x49	ffa4_on	3.49	2.47952	1	6	8
52	3x56	ffa4_on	7.33333	1.23452	3	6	5
53	4x42	ffa4_on	2.69333	1.84214	3	4	6
54	5x34	ffa4_on	3.55667	1.90929	3	4	3
55	5x47	ffa4_on	11.245	5.50143	2	4	8
56	5x60	ffa4_on	5.76	2.89643	1	4	5
57	5x69	ffa4_on	2.1	4.535	3	4	4
58	5x72	ffa4_on	1.86	1.89893	2	4	5
59	6x26	ffa4_on	0	1.97179	0	4	4
60	7x54	ffa4_on	7.06	1.98107	2	4	7
61	NT.R24	ffa4_on	6.365	3.77771	2	5	5
62	NT.K32	ffa4_on	1.74	2.82929	1	4	3
63	6x64	ffa4_on	0	2.24429	0	5	0

Orange: nodes, hubs and links specific of ffa4_on_allo network

Green: nodes, hubs and links shared by both networks

Purple: nodes, hubs and links specific of ffa4_on network

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Owner: the name of the network the link belong to or "Shared" if the corresponding link is present in both networks.

Recurrence: the relative Recurrence in the filtered pool of shortest paths.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Owner	ffa4_on_allo Recurrence	ffa4_on Recurrence	ffa4_on_allo Hub1?	ffa4_on Hub1?	ffa4_on_allo Hub2?	ffa4_on Hub2?	ConSurf1	ConSurf2
1	E2.I197	E2.R178	ffa4_on_allo	14.2258	2.7773	No	No	No	No	4	4
2	4x64	E2.R178	ffa4_on_allo	19.8411	0	Yes	No	No	No	5	4
3	4x64	E2.W198	ffa4_on_allo	28.1814	5.9742	Yes	No	Yes	Yes	5	7
4	E2.W198	E2x52	ffa4_on_allo	19.7915	1.99235	Yes	Yes	Yes	No	7	5
5	6x58	Lig	ffa4_on_allo	24.1216	7.91802	No	No	Yes	Yes	5	0
6	E2x52	Lig	ffa4_on_allo	31.1931	0	Yes	No	Yes	Yes	5	0
7	5x36	E2.W198	ffa4_on_allo	15.0918	0.27402	Yes	Yes	Yes	Yes	5	7
8	7x31	NT.F25	ffa4_on_allo	20.5637	0	No	No	Yes	Yes	4	5
9	3x29	4x65	ffa4_on_allo	20.3321	1.54136	Yes	Yes	Yes	No	5	5
10	4x65	E2x52	ffa4_on_allo	19.6867	0.205515	Yes	No	Yes	No	5	5
11	3x32	7x42	ffa4_on_allo	22.2516	0	Yes	No	Yes	No	7	7
12	3x32	Lig	ffa4_on_allo	22.4282	3.04847	Yes	No	Yes	Yes	7	0
13	NT.P26	NT.S29	ffa4_on_allo	10.0336	1.39008	No	No	No	No	5	9
14	7x31	NT.D30	ffa4_on_allo	19.5157	9.64492	No	No	Yes	Yes	4	6
15	1x39	2x61	ffa4_on_allo	15.1856	8.04932	No	Yes	Yes	No	6	6
16	1x46	2x54	ffa4_on_allo	19.626	1.49569	No	No	No	No	8	6
17	1x46	7x46	ffa4_on_allo	16.1619	1.94953	No	No	No	No	8	9
18	2x46	2x50	ffa4_on_allo	34.1552	0	Yes	No	Yes	No	9	9
19	3x43	6x45	ffa4_on_allo	53.5551	0	No	No	Yes	Yes	8	9
20	6x48	Lig	ffa4_on_allo	100	0	Yes	No	Yes	Yes	9	0
21	1x50	2x51	ffa4_on_allo	10.9162	1.16458	Yes	Yes	No	No	9	7
22	2x42	4x46	ffa4_on_allo	10.4198	0	No	No	No	No	7	7
23	2x45	4x46	ffa4_on_allo	12.1187	1.22452	No	Yes	No	No	9	7
24	2x53	7x41	ffa4_on_allo	10.5963	0	Yes	No	No	No	7	8
25	6x48	7x41	ffa4_on_allo	12.1077	0	Yes	No	No	No	9	8
26	E1x50	E1x52	ffa4_on_allo	13.8949	6.174	Yes	Yes	Yes	No	9	6
27	3x25	E1x50	ffa4_on_allo	13.6853	7.68967	No	No	Yes	Yes	9	9
28	3x25	4x65	ffa4_on_allo	15.8917	0	No	No	Yes	No	9	5
29	E1x50	E2x50	ffa4_on_allo	13.6632	1.53565	Yes	Yes	Yes	No	9	9
30	4x65	E2x50	ffa4_on_allo	24.9821	0	Yes	No	Yes	No	5	9
31	5x461	Lig	ffa4_on_allo	14.9374	0	Yes	No	Yes	Yes	6	0
32	3x40	5x50	ffa4_on_allo	11.2472	4.74967	No	No	No	No	8	9
33	3x51	5x61	ffa4_on_allo	18.0429	5.01513	Yes	Yes	No	No	8	8
34	3x51	3x56	ffa4_on_allo	12.7144	0	Yes	Yes	No	Yes	8	5
35	5x36	E2.I201	ffa4_on_allo	12.3504	0	Yes	Yes	Yes	No	5	4
36	6x52	Lig	ffa4_on_allo	13.8507	0	No	No	Yes	Yes	7	0
37	6x34	6x38	ffa4_on_allo	12.8137	3.45664	No	No	No	No	8	8
38	5x65	6x34	ffa4_on_allo	14.5016	1.48427	No	No	No	No	8	8
39	5x61	5x65	ffa4_on_allo	16.2778	0	No	No	No	No	8	8
40	7x30	7x32	ffa4_on_allo	11.1589	1.18171	No	No	No	No	4	2
41	7x32	NT.D30	ffa4_on_allo	12.5048	0	No	No	Yes	Yes	2	6
42	6x58	NT.F25	ffa4_on_allo	21.2367	6.86191	No	No	Yes	Yes	5	5
43	2x46	7x53	ffa4_on_allo	11.2417	0	Yes	No	Yes	No	9	9
44	NT.F25	NT.P26	Shared	11.4237	20.7284	Yes	Yes	No	No	5	5
45	5x36	Lig	Shared	28.7164	18.5334	Yes	Yes	Yes	Yes	5	0
46	3x29	Lig	Shared	22.3013	21.4363	Yes	Yes	Yes	Yes	5	0
47	2x53	7x42	Shared	26.7362	53.2254	Yes	No	Yes	No	7	7
48	2x53	Lig	Shared	24.1381	51.5299	Yes	No	Yes	Yes	7	0
49	1x39	7x35	Shared	19.3502	32.5569	No	Yes	Yes	Yes	6	4
50	1x39	2x57	Shared	34.5689	41.1943	No	Yes	Yes	Yes	6	7
51	2x57	7x42	Shared	44.6026	79.9652	Yes	Yes	Yes	No	7	7
52	1x43	2x57	Shared	24.0278	92.7271	No	No	Yes	Yes	6	7
53	1x43	2x54	Shared	19.5819	93.7546	No	No	No	No	6	6
54	2x50	7x46	Shared	15.842	94.511	Yes	No	No	No	9	9
55	2x46	3x43	Shared	48.3479	100	Yes	No	No	No	9	8
56	3x40	6x45	Shared	89.5802	22.7579	No	No	Yes	Yes	8	9
57	3x40	6x48	Shared	95.7968	25.4638	No	No	Yes	No	8	9
58	1x50	2x50	Shared	35.4515	25.0813	Yes	Yes	Yes	No	9	9
59	1x50	2x47	Shared	21.2036	18.8132	Yes	Yes	Yes	Yes	9	9
60	2x47	7x54	Shared	11.6057	12.3394	Yes	Yes	No	Yes	9	7
61	2x45	3x42	Shared	29.6872	42.1505	No	Yes	No	No	9	8
62	2x46	3x42	Shared	31.1159	42.3674	Yes	No	No	No	9	8
63	2x45	4x50	Shared	18.6993	40.6719	No	Yes	Yes	Yes	9	9
64	3x50	7x53	Shared	12.8082	55.0437	Yes	No	Yes	No	9	9
65	3x47	5x54	Shared	33.5098	12.4336	No	No	No	No	8	8
66	5x54	6x45	Shared	35.0212	17.3574	No	No	Yes	Yes	8	9
67	3x47	5x57	Shared	27.8614	45.7812	No	No	No	No	8	5
68	3x51	5x57	Shared	34.9881	43.3779	Yes	Yes	No	No	8	5
69	6x47	7x45	Shared	15.6434	12.9046	Yes	Yes	No	No	8	9
70	6x48	7x45	Shared	17.3369	26.3373	Yes	No	No	No	9	9
71	5x62	6x38	Shared	11.0155	44.2941	No	No	No	No	6	8
72	3x50	5x58	Shared	10.5797	44.962	Yes	No	Yes	Yes	9	9
73	2x64	7x35	ffa4_on	5.8525	23.5143	No	No	Yes	Yes	4	4
74	2x54	7x46	ffa4_on	0	92.4159	No	No	No	No	6	9
75	2x50	7x49	ffa4_on	0.37509	97.0257	Yes	No	No	No	9	9
76	2x46	7x49	ffa4_on	1.28523	70.1661	Yes	No	No	No	9	9
77	3x43	7x53	ffa4_on	4.30801	99.5347	No	No	Yes	No	8	9
78	3x46	3x50	ffa4_on	0.204093	16.1072	No	No	Yes	No	8	9
79	2x42	3x46	ffa4_on	0	15.0425	No	No	No	No	7	8
80	2x42	3x49	ffa4_on	0	12.8789	No	No	No	Yes	7	8
81	5x43	Lig	ffa4_on	6.83987	33.6587	Yes	No	Yes	Yes	5	0
82	5x43	5x461	ffa4_on	0.877048	40.7119	Yes	No	Yes	No	5	6
83	3x37	5x461	ffa4_on	1.56655	40.3009	No	No	Yes	No	6	6
84	3x37	4x53	ffa4_on	0	40.2609	No	No	No	No	6	8
85	3x38	4x53	ffa4_on	1.84235	40.2381	No	No	No	No	7	8
86	3x38	4x50	ffa4_on	5.4388	40.2152	No	No	Yes	Yes	7	9
87	3x28	3x29	ffa4_on	0	21.0424	No	No	Yes	Yes	6	5
88	3x28	E1x50	ffa4_on	0	18.0796	No	No	Yes	Yes	6	9
89	2x64	NT.D30	ffa4_on	8.93596	23.2431	No	No	Yes	Yes	4	6
90	NT.D30	NT.K32	ffa4_on	0	10.5126	Yes	Yes	No	Yes	6	3
91	7x45	7x49	ffa4_on	0	33.8728	No	No	No	No	9	9
92	3x47	5x58	ffa4_on	4.50659	35.7424	No	No	Yes	Yes	8	9
93	6x41	7x53	ffa4_on	0	44.3369	No	No	Yes	No	8	9
94	5x58	6x41	ffa4_on	3.43097	42.2675	Yes	Yes	No	No	9	8
95	3x51	5x60	ffa4_on	1.8589	14.9826	Yes	Yes	No	Yes	8	5
96	5x40	Lig	ffa4_on	5.3009	19.2242	Yes	Yes	Yes	Yes	5	0
97	5x39	5x43	ffa4_on	3.442	12.2909	Yes	Yes	Yes	No	6	5
98	5x36	6x59	ffa4_on	1.8258	15.4821	Yes	Yes	No	No	5	4
99	5x37	6x59	ffa4_on	0	31.9233	No	No	No	No	4	4
100	5x33	5x37	ffa4_on	0	25.0271	No	No	No	No	0	4
101	5x33	5x34	ffa4_on	0	19.0301	No	No	No	Yes	0	3
102	5x32	5x34	ffa4_on	0	10.4698	No	No	No	Yes	0	3
103	5x40	6x59	ffa4_on	1.63274	19.895	Yes	Yes	No	No	5	4
104	5x58	6x38	ffa4_on	0	49.3007	Yes	Yes	No	No	9	8
105	5x62	6x35	ffa4_on	5.5436	36.8756	No	No	No	No	6	7
106	6x31	6x35	ffa4_on	0	34.9946	No	No	No	No	7	7
107	5x69	6x31	ffa4_on	0	33.5959	No	Yes	No	No	4	7
108	7x38	7x42	ffa4_on	5.90215	26.4286	No	No	Yes	No	5	7
109	7x34	7x38	ffa4_on	2.7525	24.5019	Yes	Yes	No	No	4	5
110	7x34	NT.F25	ffa4_on	2.47118	28.5837	Yes	Yes	Yes	Yes	4	5
111	E2.I193	NT.P26	ffa4_on	0	18.1195	No	No	No	No	4	5
112	E2.I193	NT.R24	ffa4_on	0	11.3404	No	No	No	Yes	4	5
113	E3.I298	NT.F25	ffa4_on	0	12.0255	Yes	No	Yes	Yes	0	5
114	5x69	I3.Y247	ffa4_on	0	24.559	No	Yes	Yes	Yes	4	4
115	6x23	I3.Y247	ffa4_on	0.275801	14.6372	No	No	Yes	Yes	2	4
116	6x57	E3.I298	ffa4_on	2.82972	10.9779	No	No	Yes	No	5	0
117	3x51	3x55	ffa4_on	0	21.4906	Yes	Yes	No	No	8	6
118	3x55	3x56	ffa4_on	5.45535	19.0301	No	No	No	Yes	6	5

Here, those paths that begin and end at given residue pair(s) or that pass through a residue are used to generate a novel metapath. Such a path filtering is particularly recommended if some information on allosteric residues is available. The selection syntax for a residue pair ("Pairs") is C:C:c534,A:A:?600 (the lower-case "c" stands for cytosine and "?" indicates any non standard amino acid or nucleotide residue). Selection of more than one apical residue pair has the following syntax: C:C:c534,A:A:?600,C:C:c534,A:A:E41. Only one residue can be selected as a tail ("Tail"). For midway residue(s), each residue must be separated by a comma as well e.g. A:A:?600,A:A:E41.

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Node1	Node2	Owner	Net1LinkStrength	Net2LinkStrength	Comm1	Comm2	Node1Shell	Node2Shell
2x53	3x35	Shared	6.98286	9.25	0	0	1	2
2x53	7x42	Shared	8.88143	7.5	0	0	1	2
2x53	Lig	Shared	3.44571	4.22	0	0	1	0
3x28	3x29	ffa4_on	3.65286	0	0	0	2	1
3x29	4x65	Shared	13.1643	18.22	0	1	1	2
3x29	Lig	Shared	3.95857	11.81	0	1	1	0
3x32	Lig	Shared	6.88143	9.79	0	1	1	0
3x33	4x61	Shared	5.89428	5.9	0	1	1	1
3x33	Lig	Shared	4.69	11.23	0	1	1	0
3x36	Lig	ffa4_on	3.44	0	0	0	1	0
3x37	5x461	Shared	6.17286	8.94	0	1	2	1
3x40	6x48	Shared	12.0786	16.44	0	0	2	1
4x52	5x461	Shared	7.80571	2.33	0	0	2	1
4x60	5x39	Shared	9.84286	12.16	0	1	2	2
4x61	4x65	ffa4_on	3.30571	0	0	1	1	2
4x61	5x39	ffa4_on	5.69429	0	0	1	1	2
4x65	E2x52	Shared	13.0486	8.53	0	1	2	1
E2	E2	ffa4_on	4.11857	0	1	0	2	2
5x36	E2	ffa4_on	4.67286	0	1	1	1	2
5x36	6x59	Shared	3.97714	5.3	1	1	1	2
5x36	Lig	Shared	5.18571	4.59	1	1	1	0
5x39	5x40	Shared	4.78857	7.82	0	1	2	1
5x39	5x43	Shared	13.1729	11.02	0	1	2	1
5x40	6x55	Shared	3.4	5.6	1	1	1	1
5x40	6x59	Shared	9.30714	16.29	1	1	1	2
5x40	Lig	Shared	11.1271	7.52	1	1	1	0
5x43	5x461	Shared	8.97714	9.67	0	1	1	1
5x43	Lig	Shared	6.25571	9.28	0	1	1	0
5x44	6x52	Shared	4.16857	4.61	0	0	2	1
5x47	6x52	Shared	12.0229	18.84	0	0	2	1
6x48	7x45	Shared	19.8557	19.21	0	0	1	2
6x51	7x41	Shared	4.99429	12.16	0	0	1	2
6x51	Lig	Shared	8.04714	18.79	0	0	1	0
6x55	Lig	Shared	8.3	15.82	1	1	1	0
6x58	Lig	Shared	6.78	9.89	0	1	1	0
7x34	7x38	Shared	5.05429	5.24	1	1	1	2
7x34	Lig	ffa4_on	3.79	0	1	1	1	0
7x38	7x42	Shared	4.67857	3.93	1	1	2	2
NT.F25	NT.F27	Shared	6.73714	7.5	1	1	2	2
6x58	NT.F25	Shared	4.12571	5.02	0	1	1	2
7x34	NT.F25	Shared	3.82714	9.65	1	1	1	2
3x29	NT.F27	Shared	3.67286	9.65	0	1	1	2
7x34	NT.F27	ffa4_on	5.05286	0	1	1	1	2
7x34	NT.F28	Shared	4.74714	5.36	1	1	1	2
7x38	NT.F28	Shared	4.68286	7.87	1	1	2	2
E2.W198	E2x52	Shared	9.11	10.25	1	1	1	1
5x36	E2.W198	Shared	18.07	11.99	1	1	1	1
5x39	E2.W198	Shared	5.22	14.99	0	1	2	1
E2.W198	Lig	ffa4_on	4.22429	0	1	1	1	0
5x36	6x62	ffa4_on	6.57143	0	1	1	1	2
3x33	4x57	Shared	3.12	3.36	0	1	1	2
3x39	6x48	Shared	3.12	4.85	0	0	2	1
4x64	E2.W198	Shared	3.00571	11.02	0	0	2	1
4x52	4x56	ffa4_on	2.85857	0	0	0	2	2
2x56	3x32	Shared	2.76	3.22	0	0	2	1
6x54	7x34	ffa4_on	2.59143	0	0	0	2	1
4x65	NT.F27	ffa4_on_allo	0	7.5	0	1	2	2
E2x52	NT.F27	ffa4_on_allo	0	6.09	0	1	1	2
3x29	NT.F28	ffa4_on_allo	0	7.5	0	1	1	2
2x53	7x41	ffa4_on_allo	0	5.19	0	0	1	2
3x29	3x32	ffa4_on_allo	0	7.46	0	1	1	1
3x29	4x61	ffa4_on_allo	0	7.31	0	1	1	1
3x32	7x42	ffa4_on_allo	0	3.73	0	1	1	2
3x33	5x43	ffa4_on_allo	0	3.89	0	1	1	1
3x36	6x48	ffa4_on_allo	0	4.22	0	0	1	1
3x37	5x43	ffa4_on_allo	0	5.28	0	1	2	1
3x41	5x461	ffa4_on_allo	0	8.24	0	0	2	1
4x60	E2.W198	ffa4_on_allo	0	5.4	0	1	2	1
4x61	E2x52	ffa4_on_allo	0	5.54	0	1	1	1
4x61	Lig	ffa4_on_allo	0	3.84	0	1	1	0
E2x52	Lig	ffa4_on_allo	0	3.84	0	1	1	0
5x36	E2.I201	ffa4_on_allo	0	4.1	1	1	1	2
E2.I201	E3.N291	ffa4_on_allo	0	7.08	0	1	2	2
5x36	E3.N291	ffa4_on_allo	0	6.57	1	1	1	2
5x461	Lig	ffa4_on_allo	0	3.81	0	1	1	0
6x48	7x41	ffa4_on_allo	0	3.64	0	0	1	2
6x48	Lig	ffa4_on_allo	0	7.1	0	0	1	0
6x52	Lig	ffa4_on_allo	0	4.94	0	0	1	0
6x58	7x34	ffa4_on_allo	0	3.77	0	1	1	1
6x51	6x54	ffa4_on_allo	0	3.04	0	0	1	2
4x56	5x43	ffa4_on_allo	0	2.77	0	0	2	1

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Difference Members
	Id	Description
	ffa4_on_allo	8T3O-FFA4-TUG-891-2Y5-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
	ffa4_on	8H4K-FFA4-GW9508-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 8ID9-FFA4 (GPR120)-Eicosapentaenoic acid-Gi1/&β;1/&γ;2 8ID4-FFA4 (GPR120)-Linoleic acid-Gi1/&β;1/&γ;2 8ID6-FFA4 (GPR120)-Oleic acid-Gi1/&β;1/&γ;2 8G59-FFA4 (GPR120)-TUG-891-Gi1/&β;1/&γ;2 8ID3-FFA4 (GPR120)-9-Hydroxystearic acid-Gi1/&β;1/&γ;2 8H4I-FFA4-Doconexent-chim(NtGi1-Gs)/&β;1/&γ;2

Network Difference
Value	ffa4_on_allo	ffa4_on
I_min	3.62	3.26571
Number of Linked Nodes	274	313
Number of Specific Nodes	5 (1.82%)	44 (14.06%)
Number of Shared Nodes	269 (98.18%)	269 (85.94%)
Number of Links	313	335
Number of Specific Links	124 (39.62%)	146 (43.58%)
Number of Shared Links	189 (60.38%)	189 (56.42%)
Number of Hubs	46	38
Number of Specific Hubs	25 (54.35%)	17 (44.74%)
Number of Shared Hubs	21 (45.65%)	21 (55.26%)
Average % Shared Neighbours (Jaccard)	41.60
Average % Shared Neighbours (Otsuka)	50.18
Average % Shared Neighbours (Overlap Coefficient)	58.87
Average % Shared Cliques (k3-6)	77.94
Graphlets Similarity	0.529297

Paths Difference
Value	ffa4_on_allo	ffa4_on
Number Of Nodes in MetaPath	67	72
Specific Nodes in MetaPath	26 (38.81%)	31 (43.06%)
Shared Nodes in MetaPath	269 (98.18%)	269 (98.18%)
Number Of Links MetaPath	72	75
Specific Links in MetaPath	43 (59.72%)	46 (61.33%)
Shared Links in MetaPath	189 (60.38%)	189 (60.38%)
Number of Shortest Paths	44760	77118
Length Of Smallest Path	3	3
Average Path Length	10.8419	16.2496
Length of Longest Path	26	32
Minimum Path Strength	1.285	0.415714
Average Path Strength	6.88928	5.36614
Maximum Path Strength	19.44	15.9671
Minimum Path Correlation	0.7	0.7
Average Path Correlation	0.939216	0.90479
Maximum Path Correlation	1	0.99
Minimum % Of Corr. Nodes	5.26316	3.44828
Average % Of Corr. Nodes	68.0485	40.8105
Maximum % Of Corr. Nodes	100	100
Minimum Path Hubs %	0	0
Average Path Hubs %	50.9118	29.2595
Maximum Path Hubs %	100	100

Details about the values in these tables can be found in the corresponding documentation page .

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