Orange: nodes, hubs and links specific of h1_on_gp network

Green: nodes, hubs and links shared by both networks

Purple: nodes, hubs and links specific of h1_off network

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Owner: the name of the network the hub belong to or "Shared" if the corresponding hub is present in both networks.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub in the corresponding network.

Num Of Links: the number of links of the corresponding hub in the corresponding network.

ConSurf: this column reports the ConSurf conservation grades of each hub.


Index Hub Owner h1_on_gp Avg Int. Strength h1_off Avg Int. Strength h1_on_gp Num Of Links h1_off Num Of Links ConSurf
1b.1x1 h1_on_gp1.87750404
2b.lh12x2 h1_on_gp4.380408
3b.h2x1 h1_on_gp3.1050605
4b.lhb1x6 h1_on_gp4.440403
5b.b1x6 h1_on_gp9.57750409
6b.l1x3 h1_on_gp7.790709
7b.b2x5 h1_on_gp6.460507
8b.b3x3 h1_on_gp4.20750408
9b.l3x1 h1_on_gp8.50250409
10b.l3x2 h1_on_gp7.34750409
11b.b4x3 h1_on_gp4.5550407
12b.b4x5 h1_on_gp5.1480507
13b.b4x6 h1_on_gp10.39830609
14b.b5x2 h1_on_gp6.30407
15b.b5x3 h1_on_gp7.40609
16b.b5x5 h1_on_gp6.0220505
17b.l5x1 h1_on_gp4.4750408
18b.l5x5 h1_on_gp7.940709
19b.b6x1 h1_on_gp5.530509
20b.b6x5 h1_on_gp5.067140706
21b.b8x3 h1_on_gp4.83250406
22b.b8x4 h1_on_gp6.6680506
23b.l8x1 h1_on_gp4.7160505
24b.l8x8 h1_on_gp5.730404
25b.l9x3 h1_on_gp6.370609
26b.l9x6 h1_on_gp12.5120508
27b.b10x2 h1_on_gp3.1950406
28b.b10x5 h1_on_gp4.764290709
29b.l10x1 h1_on_gp3.63750403
30b.b11x2 h1_on_gp5.030407
31b.b11x4 h1_on_gp4.6550609
32b.l11x2 h1_on_gp6.3260509
33b.b12x2 h1_on_gp4.06250407
34b.b12x3 h1_on_gp4.7660508
35b.b12x6 h1_on_gp7.548330608
36b.l12x1 h1_on_gp5.250406
37b.b13x7 h1_on_gp8.2440507
38b.l13x3 h1_on_gp8.4380509
39b.l13x6 h1_on_gp7.850409
40b.l13x7 h1_on_gp4.6850409
41b.b14x3 h1_on_gp5.0050405
42b.b15x1 h1_on_gp8.550509
43b.b15x3 h1_on_gp4.60750409
44b.l15x2 h1_on_gp6.01750409
45b.b16x6 h1_on_gp8.930508
46b.b16x7 h1_on_gp7.63750409
47b.b17x5 h1_on_gp7.650507
48b.b17x7 h1_on_gp7.81750408
49b.l17x3 h1_on_gp8.420609
50b.l17x7 h1_on_gp6.59750407
51b.b18x3 h1_on_gp5.9860508
52b.b18x5 h1_on_gp4.6150605
53b.l18x1 h1_on_gp6.794290706
54b.b19x2 h1_on_gp7.071250806
55b.b19x4 h1_on_gp6.7440508
56b.l19x2 h1_on_gp6.8760509
57b.b20x2 h1_on_gp4.070406
58b.b20x4 h1_on_gp8.4760508
59b.l20x1 h1_on_gp4.20750406
60b.b21x1 h1_on_gp10.76750407
61b.b21x7 h1_on_gp7.5840505
62b.l21x5 h1_on_gp5.4050404
63b.b22x4 h1_on_gp3.23250405
64b.b22x5 h1_on_gp5.146670607
65b.l22x5 h1_on_gp5.6360509
66b.b23x2 h1_on_gp5.480406
67b.b23x3 h1_on_gp3.903330607
68b.b23x6 h1_on_gp7.7740507
69b.l23x1 h1_on_gp5.980406
70b.b24x3 h1_on_gp3.420405
71b.b24x5 h1_on_gp3.740505
72b.b24x6 h1_on_gp10.59750408
73b.l24x2 h1_on_gp4.130406
74b.b25x7 h1_on_gp5.8860507
75b.l25x3 h1_on_gp10.4560509
76b.l25x6 h1_on_gp9.2360508
77b.b26x3 h1_on_gp4.50506
78b.l26x1 h1_on_gp5.81250407
79b.b27x1 h1_on_gp3.95750406
80b.b27x3 h1_on_gp5.430408
81b.l27x1 h1_on_gp16.24250409
82b.l27x2 h1_on_gp6.870409
83b.b28x3 h1_on_gp5.086670607
84b.b28x4 h1_on_gp9.1350406
85b.b28x6 h1_on_gp7.550609
86b.b28x7 h1_on_gp5.49750409
87g.h1x1 h1_on_gp1.99750402
88g.h1x8 h1_on_gp3.72750407
89g.h1x11 h1_on_gp4.490409
90g.l1x4 h1_on_gp6.9140508
91g.ctx3 h1_on_gp8.0760509
92g.ctx5 h1_on_gp5.43750409
93g.ctx6 h1_on_gp3.9150606
94g.ctx15 h1_on_gp7.88250409
95g.ctx16 h1_on_gp5.081110908
961x39 h1_on_gp4.597510.2233428
971x46 h1_on_gp6.2957.49333429
982x40 h1_on_gp5.277.10556439
992x46 h1_on_gp6.14.42444439
1002x59 h1_on_gp6.3546.14833528
1012x60 h1_on_gp8.356.27428
1022x64 h1_on_gp2.64.23167428
103E1x52 h1_on_gp6.63753.95833429
1043x28 h1_on_gp9.56.03222539
1053x29 h1_on_gp4.1783.17333519
1063x32 h1_on_gp10.3958.08439
1073x33 h1_on_gp9.6189.61222539
1083x45 h1_on_gp3.93757.27667428
109I2x56 h1_on_gp10.20756.02556438
1104x50 h1_on_gp4.7945.07889539
1114x53 h1_on_gp2.98755.33333419
112E2.F168 h1_on_gp6.42251.66416
113E2.Q171 h1_on_gp9.06754.01667412
114E2.V174 h1_on_gp7.344.36412
115E2x50 h1_on_gp6.3155.66111439
116E2x51 h1_on_gp5.569.44833427
1175x461 h1_on_gp7.828.41778439
1185x48 h1_on_gp6.6854.08889438
1195x57 h1_on_gp7.84257.05667437
1206x29 h1_on_gp8.8850.826667418
1216x52 h1_on_gp9.5933315.8278639
1227x53 h1_on_gp5.5545.86333539
1238x48 h1_on_gp5.081.8435
1248x50 h1_on_gp5.0556.12667439
125G.S1.04 h1_on_gp4.8080506
126G.S1.06 h1_on_gp5.0340508
127G.H1.01 h1_on_gp4.8760509
128G.H1.04 h1_on_gp7.2080507
129G.S2.03 h1_on_gp8.60750409
130G.S2.06 h1_on_gp5.27750408
131G.S3.03 h1_on_gp5.40750407
132G.S3.05 h1_on_gp6.31750407
133G.H2.06 h1_on_gp8.61250409
134G.H2.07 h1_on_gp9.782860709
135G.h2s4.01 h1_on_gp6.680409
136G.S4.02 h1_on_gp4.59750407
137G.S4.03 h1_on_gp4.3380507
138G.S4.05 h1_on_gp4.78750407
139G.s4h3.03 h1_on_gp9.83250407
140G.s4h3.04 h1_on_gp7.110408
141G.H3.09 h1_on_gp10.130409
142G.H3.17 h1_on_gp4.6550405
143G.S5.05 h1_on_gp5.06750409
144G.S5.06 h1_on_gp4.8580508
145G.HG.15 h1_on_gp6.94250406
146G.hgh4.01 h1_on_gp6.7160505
147G.hgh4.02 h1_on_gp7.3940508
148G.hgh4.05 h1_on_gp7.20250406
149G.H4.12 h1_on_gp4.83750405
150G.S6.01 h1_on_gp3.1150406
151G.S6.02 h1_on_gp5.7880508
152G.s6h5.01 h1_on_gp5.750609
153G.s6h5.05 h1_on_gp7.1040509
154G.H5.20 h1_on_gp5.030408
1552x42 Shared6.373335.95429678
1562x50 Shared7.5566.12833549
1572x57 Shared5.133335.064659
158E1x50 Shared7.943756.22722869
1593x37 Shared7.0366.17549
1603x51 Shared9.45756.9525449
1614x57 Shared7.8247.404558
162E2.F184 Shared5.72258.89083449
1635x39 Shared4.1925.84559
1645x47 Shared11.39810.345549
1655x54 Shared5.875.06333449
1665x58 Shared5.94753.64833449
1676x44 Shared6.13756.28667449
1686x48 Shared6.87.42833769
1696x51 Shared7.693337.58111669
1707x38 Shared5.738335.08417648
1717x39 Shared4.997.02524779
1727x42 Shared6.973756.11333869
1738x54 Shared4.4655.01733459
174Lig Shared10.119.216119120
1752x56 h1_off7.136675.97583349
1762x66 h1_off6.131.33083145
177I2x52 h1_off10.52675.0575345
178I2x53 h1_off4.063333.7375349
179I2x57 h1_off3.973335.77867359
180E2.W165 h1_off3.846675.23167369
1816x31 h1_off03.18667047
1827x34 h1_off6.636.0675147
1837x45 h1_off10.255.94667359
   
Orange: nodes, hubs and links specific of h1_on_gp network

Green: nodes, hubs and links shared by both networks

Purple: nodes, hubs and links specific of h1_off network

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Owner: the name of the network the link belong to or "Shared" if the corresponding link is present in both networks.

Recurrence: the relative Recurrence in the filtered pool of shortest paths.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.


Index Node1 Node2 Owner h1_on_gp Recurrence h1_off Recurrence h1_on_gp Hub1? h1_off Hub1? h1_on_gp Hub2? h1_off Hub2? ConSurf1 ConSurf2
1b.1x11 g.h1x12 h1_on_gp10.5990NoNoNoNo86
2b.1x11 g.h1x11 h1_on_gp11.27310NoNoYesNo89
3g.h1x11 g.h1x14 h1_on_gp12.2820YesNoNoNo99
4b.b19x2 b.b19x4 h1_on_gp10.7170YesNoYesNo68
5b.b19x4 b.l17x3 h1_on_gp18.23130YesNoYesNo89
6b.b19x6 b.l17x3 h1_on_gp11.07930NoNoYesNo99
7b.b19x6 b.l17x5 h1_on_gp11.25120NoNoNoNo96
8b.l17x5 b.l19x1 h1_on_gp24.20330NoNoNoNo69
9b.l19x1 b.l21x8 h1_on_gp34.00790NoNoNoNo94
10b.l21x8 b.l23x1 h1_on_gp33.88580NoNoYesNo46
11b.l21x7 b.l23x1 h1_on_gp19.59520NoNoYesNo56
12b.l21x7 b.l23x2 h1_on_gp19.36270NoNoNoNo58
13b.b23x6 b.l23x2 h1_on_gp18.43370YesNoNoNo78
14b.b23x6 b.b24x6 h1_on_gp11.46370YesNoYesNo78
15b.b21x7 b.b24x6 h1_on_gp11.22560YesNoYesNo58
16b.l17x3 b.l19x2 h1_on_gp11.14770YesNoYesNo99
17b.l17x5 b.l19x2 h1_on_gp12.79710NoNoYesNo69
18b.b22x1 b.l23x1 h1_on_gp19.51590NoNoYesNo86
19b.b22x1 b.b22x2 h1_on_gp19.32360NoNoNoNo88
20b.b22x2 b.b26x3 h1_on_gp19.14290NoNoYesNo86
21b.b23x3 b.b26x3 h1_on_gp14.42610YesNoYesNo76
22b.b10x2 b.b14x3 h1_on_gp15.05490YesNoYesNo65
23b.b10x1 b.b10x2 h1_on_gp18.49460NoNoYesNo96
24G.H2.07 b.b10x1 h1_on_gp17.15130YesNoNoNo99
25b.l5x5 b.l7x2 h1_on_gp40.11740YesNoNoNo99
26G.S1.03 b.l5x5 h1_on_gp44.90460NoNoYesNo99
27G.S1.03 b.l3x1 h1_on_gp44.79360NoNoYesNo99
28b.l1x5 b.l3x1 h1_on_gp38.32040NoNoYesNo79
29b.l1x5 b.l3x2 h1_on_gp38.06190NoNoYesNo79
30b.l1x3 b.l3x2 h1_on_gp36.53210YesNoYesNo99
31b.b4x6 b.l1x3 h1_on_gp25.04410YesNoYesNo99
32b.b1x6 b.b4x6 h1_on_gp18.87690YesNoYesNo99
33b.b1x6 b.b28x5 h1_on_gp18.01610YesNoNoNo95
34b.b28x5 g.ctx16 h1_on_gp15.87350NoNoYesNo58
35G.H2.07 b.l9x6 h1_on_gp42.4030YesNoYesNo98
36b.l7x2 b.l9x6 h1_on_gp36.44450NoNoYesNo98
37b.l4x2 g.ctx16 h1_on_gp15.99420NoNoYesNo48
38b.l2x5 b.l4x2 h1_on_gp16.44080NoNoNoNo54
39b.l2x3 b.l2x5 h1_on_gp11.27130NoNoNoNo85
40b.b3x1 b.l2x3 h1_on_gp10.89980NoNoNoNo58
41b.b3x1 b.b6x5 h1_on_gp10.52810NoNoYesNo56
42G.S2.03 b.l5x5 h1_on_gp30.90860YesNoYesNo99
43G.S2.01 G.S2.03 h1_on_gp31.04470NoNoYesNo99
44G.S2.01 G.S3.08 h1_on_gp31.13940NoNoNoNo99
45G.S3.08 b.l9x6 h1_on_gp69.39980NoNoYesNo98
46G.h2s4.01 b.l5x5 h1_on_gp43.76870YesNoYesNo99
47G.H2.07 b.l11x1 h1_on_gp16.7180YesNoNoNo99
48b.b11x6 b.l11x1 h1_on_gp16.56170NoNoNoNo99
49b.b11x6 b.l9x3 h1_on_gp14.52750NoNoYesNo99
50b.b11x4 b.l9x3 h1_on_gp11.34260YesNoYesNo99
51b.b11x2 b.b11x4 h1_on_gp10.65260YesNoYesNo79
52G.H2.06 b.b14x1 h1_on_gp25.48320YesNoNoNo98
53G.H2.06 b.b18x1 h1_on_gp33.60310YesNoNoNo99
542x53 7x42 h1_on_gp20.33680NoNoYesYes99
552x46 2x50 h1_on_gp23.89660YesNoYesYes99
563x46 7x53 h1_on_gp32.37430NoNoYesNo99
572x42 3x46 h1_on_gp16.73931.59701YesYesNoNo89
583x49 3x53 h1_on_gp49.63520NoNoNoNo99
593x53 G.H5.19 h1_on_gp85.06240NoNoNoNo98
60G.H5.15 G.H5.19 h1_on_gp85.19820NoNoNoNo88
61G.H5.11 G.H5.15 h1_on_gp85.34590NoNoNoNo88
62G.H5.11 G.S1.04 h1_on_gp84.95640NoNoYesNo86
63G.S1.04 G.S4.03 h1_on_gp89.41780YesNoYesNo67
64G.S1.06 G.S4.03 h1_on_gp90.11130YesNoYesNo87
65G.H1.01 G.S1.06 h1_on_gp90.00390YesNoYesNo98
66G.H1.01 G.s3h2.01 h1_on_gp99.80110YesNoNoNo99
67G.S3.08 G.s3h2.01 h1_on_gp1000NoNoNoNo99
687x42 Lig h1_on_gp11.07430YesYesYesYes90
693x37 Lig h1_on_gp17.42860YesYesYesYes90
703x37 4x53 h1_on_gp28.17582.94765YesYesYesNo99
714x50 4x53 h1_on_gp29.95470YesNoYesNo99
722x45 4x50 h1_on_gp31.58086.34844NoNoYesNo99
733x46 3x50 h1_on_gp16.38930NoNoNoNo99
743x50 G.H5.23 h1_on_gp35.18650NoNoNoNo94
753x53 G.H5.23 h1_on_gp35.32870NoNoNoNo94
762x60 3x28 h1_on_gp12.14340YesNoYesNo89
773x37 4x57 h1_on_gp10.69899.26089YesYesYesYes98
785x54 6x44 h1_on_gp11.71990YesYesYesYes99
793x47 5x54 h1_on_gp12.49462.20414NoNoYesYes89
803x47 5x58 h1_on_gp14.04490NoNoYesYes89
813x50 5x58 h1_on_gp19.07340NoNoYesYes99
82G.S1.05 G.h2s4.01 h1_on_gp21.91330NoNoYesNo99
83G.S1.05 G.S1.07 h1_on_gp21.63420NoNoNoNo99
84G.H3.18 G.S4.02 h1_on_gp10.68170NoNoYesNo97
85G.H2.08 G.H3.18 h1_on_gp10.88970NoNoNoNo89
86G.H2.08 G.H3.17 h1_on_gp11.57010NoNoYesNo85
87G.H3.02 G.s4h3.03 h1_on_gp20.43530NoNoYesNo87
88G.H3.02 G.H4.11 h1_on_gp21.50790NoNoNoNo88
89G.H4.11 G.s4h3.01 h1_on_gp22.58020NoNoNoNo87
90G.S5.06 G.s4h3.01 h1_on_gp24.7240YesNoNoNo87
91G.S5.04 G.S5.06 h1_on_gp12.83660NoNoYesNo88
92G.H3.09 G.S5.04 h1_on_gp13.37150YesNoNoNo98
93G.H3.09 G.S6.01 h1_on_gp32.06480YesNoYesNo96
94G.S5.02 G.S6.01 h1_on_gp48.52940NoNoYesNo66
95G.S4.02 G.S5.02 h1_on_gp52.2480YesNoNoNo76
96G.H4.12 G.S5.06 h1_on_gp12.8450YesNoYesNo58
97G.H4.12 G.H4.16 h1_on_gp15.50030YesNoNoNo53
98G.H4.16 G.S6.01 h1_on_gp16.03520NoNoYesNo36
99G.S4.07 G.s4h3.03 h1_on_gp12.91880NoNoYesNo87
100G.h2s4.01 G.h2s4.04 h1_on_gp21.62290YesNoNoNo99
101G.h2s4.04 G.h3s5.03 h1_on_gp21.3420NoNoNoNo97
102G.H3.09 G.H4.15 h1_on_gp17.65150YesNoNoNo99
103G.H3.06 G.H4.14 h1_on_gp14.58130NoNoNoNo75
104G.H3.06 G.H4.15 h1_on_gp16.72330NoNoNoNo79
105b.b18x1 b.l19x1 h1_on_gp33.52550NoNoNoNo99
106G.H2.07 b.b14x1 h1_on_gp24.04650YesNoNoNo98
107G.S1.07 G.S4.02 h1_on_gp21.20480NoNoYesNo97
108G.S4.02 G.h3s5.03 h1_on_gp21.11790YesNoNoNo77
1092x57 7x42 Shared15.928626.674YesYesYesYes99
1102x53 7x46 Shared21.15126.4364NoNoNoNo99
1112x50 7x46 Shared21.542826.41YesYesNoNo99
1122x46 7x53 Shared28.480254.0519YesNoYesNo99
1132x42 3x49 Shared49.49137.4747YesYesNoNo89
1142x45 4x46 Shared31.643752.1205NoNoNoNo99
1152x42 4x46 Shared31.832148.2402YesYesNoNo89
1161x39 7x39 h1_off1.7784715.4509YesNoYesYes89
1177x39 7x42 h1_off4.4336139.2301YesYesYesYes99
1182x56 7x42 h1_off0.030280615.4817NoYesYesYes99
1192x53 2x56 h1_off0.42789828.6274NoNoNoYes99
1201x50 2x50 h1_off3.7590615.0418NoNoYesYes99
1211x50 7x50 h1_off1.354110.1672NoNoNoNo99
1222x50 7x49 h1_off0.54299336.9688YesYesNoNo99
1232x46 7x49 h1_off4.39775100YesNoNoNo99
1242x43 7x53 h1_off051.8038NoNoYesNo99
1252x40 2x43 h1_off0.44847750.5279YesNoNoNo99
1262x40 I1x50 h1_off0.0091135947.9323YesNoNoNo99
1278x50 I1x50 h1_off0.059091345.6269YesNoNoNo99
1288x50 8x54 h1_off3.0249835.033YesNoYesYes99
1293x32 7x42 h1_off0.049095822.6661YesNoYesYes99
1303x32 Lig h1_off0.24753747.3647YesNoYesYes90
1316x48 Lig h1_off074.4215YesYesYesYes90
1326x48 7x45 h1_off3.1084766.7708YesYesNoYes99
1337x45 7x49 h1_off4.5472484.4699NoYesNoNo99
1347x38 7x42 h1_off0.058944338.7989YesYesYesYes89
1357x38 Lig h1_off5.2085627.6375YesYesYesYes80
1366x51 7x38 h1_off0.62560413.3656YesYesYesYes98
1376x48 6x51 h1_off3.3930522.4593YesYesYesYes99
1381x53 8x54 h1_off011.0031NoNoYesYes99
1391x56 8x54 h1_off010.6775NoNoYesYes99
1402x46 3x42 h1_off059.6436YesNoNoNo98
1412x45 3x42 h1_off0.12038858.4118NoNoNoNo98
1422x54 2x57 h1_off5.8247610.2508NoNoYesYes99
1432x56 3x28 h1_off035.9569NoYesYesNo99
1443x28 E1x50 h1_off6.0877332.4593YesNoYesYes99
1452x63 E1x50 h1_off0.0042628111.1703NoNoYesYes79
1461x35 1x39 h1_off0.88945712.5913NoNoYesNo98
147E1x50 E1x52 h1_off2.6395616.2121YesYesYesNo99
1483x33 Lig h1_off2.2015215.8293YesNoYesYes90
1493x33 E2x52 h1_off014.8482YesNoNoNo99
150E2.F184 E2x52 h1_off1.0680513.7527YesYesNoNo99
1514x61 E2.F184 h1_off024.7514NoNoYesYes99
1523x30 4x61 h1_off022.3317NoNoNoNo99
1533x30 4x58 h1_off0.78171119.6216NoNoNoNo95
1544x58 4x62 h1_off0.52138516.7136NoNoNoNo57
1553x26 4x62 h1_off0.26076613.8011NoNoNoNo87
1563x22 3x26 h1_off011.2978NoNoNoNo58
1575x43 Lig h1_off030.7215NoNoYesYes80
1585x39 5x43 h1_off1.2219630.4619YesYesNoNo98
1595x39 E2.F184 h1_off013.8099YesYesYesYes99
1603x37 3x41 h1_off0.23107411.751YesYesNoNo98
1613x40 Lig h1_off027.6023NoNoYesYes90
1623x40 6x44 h1_off1.7224726.6344NoNoYesYes99
1636x44 6x48 h1_off030.1672YesYesYesYes99
1643x43 6x44 h1_off069.6612NoNoYesYes99
1653x43 5x54 h1_off0.36057567.7519NoNoYesYes99
1663x44 5x54 h1_off1.4389229.4897NoNoYesYes89
1673x44 3x48 h1_off025.363NoNoNoNo86
1683x48 5x57 h1_off0.28604923.3128NoNoYesNo67
1693x51 5x57 h1_off2.6738117.0656YesYesYesNo97
1703x51 5x61 h1_off0.45479710.9107YesYesNoNo99
1713x49 I2x57 h1_off018.7813NoNoNoYes99
1723x52 I2x57 h1_off015.0682NoNoNoYes89
1733x49 I2x53 h1_off017.6067NoNoNoYes99
1743x52 I2x53 h1_off015.0374NoNoNoYes89
1756x52 Lig h1_off1.6476528.8341YesNoYesYes90
1765x47 6x52 h1_off6.3404125.9481YesYesYesNo99
1775x47 5x48 h1_off2.7324612.5253YesYesYesNo98
1785x54 6x41 h1_off035.3806YesYesNoNo99
1795x58 6x41 h1_off0.87078831.2758YesYesNoNo99
1808x47 8x50 h1_off010.7039NoNoYesNo99
1816x54 7x34 h1_off015.7633NoNoNoYes77
1827x54 8x54 h1_off012.2305NoNoYesYes99
1835x58 6x37 h1_off6.2057623.0048YesYesNoNo99
1843x52 I2x52 h1_off0.039835227.1535NoNoNoYes85
185I2x52 I2x56 h1_off5.4102415.1694NoYesYesNo58
1863x50 6x37 h1_off020.9283NoNoNoNo99
1873x50 6x34 h1_off017.7211NoNoNoNo99
1885x65 6x34 h1_off015.6621NoNoNoNo99
1895x65 6x31 h1_off014.0915NoNoNoYes97
1902x62 E1x52 h1_off014.8438NoNoYesNo69
1912x62 2x66 h1_off013.6912NoNoNoYes65
1927x54 8x51 h1_off010.6907NoNoNoNo98
1937x35 7x39 h1_off011.8038NoNoYesYes69
1942x56 3x32 h1_off0.04439223.9067NoYesYesNo99
1956x44 7x45 h1_off019.3709YesYesNoYes99
1966x51 7x34 h1_off011.5662YesYesNoYes97

Here, those paths that begin and end at given residue pair(s) or that pass through a residue are used to generate a novel metapath. Such a path filtering is particularly recommended if some information on allosteric residues is available. The selection syntax for a residue pair ("Pairs") is C:C:c534,A:A:?600 (the lower-case "c" stands for cytosine and "?" indicates any non standard amino acid or nucleotide residue). Selection of more than one apical residue pair has the following syntax: C:C:c534,A:A:?600,C:C:c534,A:A:E41. Only one residue can be selected as a tail ("Tail"). For midway residue(s), each residue must be separated by a comma as well e.g. A:A:?600,A:A:E41.

Midway



Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.


2D representation of the interactions of this orthosteric/allosteric ligand.


Node1Node2OwnerNet1LinkStrengthNet2LinkStrengthComm1Comm2Node1ShellNode2Shell
2x532x56Shared3.743333.210122
2x563x32Shared7.313.151121
2x567x42Shared6.735.051121
2x577x39Shared5.044.651122
2x577x42Shared6.783333.591121
2x607x39Shared8.663333.391122
2x607x42Shared3.8766711.631121
3x327x42Shared5.3666713.791111
3x32LigShared11.573310.221110
3x334x57Shared8.3615.431111
3x33E2x52h1_off4.5766701112
3x33LigShared15.919.861110
3x366x48Shared4.124.941111
3x36LigShared9.957.071110
3x373x41Shared4.756676.491112
3x374x53Shared5.333333.21112
3x374x57Shared7.289.71111
3x375x461Shared7.3110.241111
3x405x50h1_off6.2066700012
3x406x44Shared7.953333.770012
3x40Ligh1_off4.5900010
4x575x43Shared7.683337.281111
4x575x461h1_off9.0401111
4x57Ligh1_off4.6566701110
E2.F184E2x52Shared14.69675.191122
5x39E2.F184h1_off12.503301022
5x395x43Shared3.893337.781021
5x43Ligh1_off3.6266701010
5x461LigShared8.903337.751110
5x476x52Shared27.866723.580121
6x446x48h1_off6.0133301121
6x447x45h1_off7.2466701122
6x486x51Shared7.396672.891111
6x487x41Shared11.268.441112
6x487x45Shared3.766679.041112
6x48Ligh1_off12.013301110
6x516x55h1_off10.6601111
6x517x34h1_off4.7166701112
6x517x37Shared6.243334.991112
6x517x38Shared5.244.841111
6x51LigShared11.2324.271110
6x52LigShared16.84679.170110
6x55Ligh1_off6.3066701010
7x347x38Shared4.866.631021
7x387x42Shared5.249.671111
7x38LigShared4.996672.691110
7x397x42Shared8.683333.861121
5x406x55Shared7.0333317.370021
4x61E2.F184h1_off3.3500022
5x446x52h1_off2.7700121
4x605x39Shared1.443334.330022
2x537x42h1_on_gp03.790121
2x607x38h1_on_gp07.081121
3x323x36h1_on_gp04.421111
3x334x61h1_on_gp03.631112
3x33E2.F184h1_on_gp06.191112
3x336x51h1_on_gp02.981111
3x37Ligh1_on_gp05.551110
3x406x48h1_on_gp015.270011
3x415x461h1_on_gp07.250121
4x574x60h1_on_gp02.71112
4x57E2.F184h1_on_gp04.011112
5x4616x52h1_on_gp06.041111
5x476x44h1_on_gp04.290122
5x476x48h1_on_gp03.010121
6x486x52h1_on_gp04.011111
6x516x52h1_on_gp06.191111
6x526x55h1_on_gp08.570111
7x387x39h1_on_gp03.521112
7x42Ligh1_on_gp04.411110

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Difference Members
Id Description
h1_on_gp 7DFL-H1-Histamine-chim(NtGi1L-Gq)/β1/γ2
h1_off 8X63-H1-Mepyramine
3RZE-H1-Cidoxepin
8X5Y-H1-Astemizole
Network Difference
Value h1_on_gp h1_off
Imin 2.65 3.58
Number of Linked Nodes 848 275
Number of Specific Nodes 598 (70.52%) 25  (9.09%)
Number of Shared Nodes 250 (29.48%) 250  (90.91%)
Number of Links 1067 295
Number of Specific Links 915 (85.75%) 143  (48.47%)
Number of Shared Links 152 (14.25%) 152  (51.53%)
Number of Hubs 174 29
Number of Specific Hubs 154 (88.51%) 9  (31.03%)
Number of Shared Hubs 20 (11.49%) 20  (68.97%)
Average % Shared Neighbours (Jaccard) 10.50
Average % Shared Neighbours (Otsuka) 13.78
Average % Shared Neighbours (Overlap Coefficient) 16.90
Average % Shared Cliques (k3-6) 50.93
Graphlets Similarity 0.627071
Paths Difference
Value h1_on_gp h1_off
Number Of Nodes in MetaPath 112 82
Specific Nodes in MetaPath 94 (83.93%) 64  (78.05%)
Shared Nodes in MetaPath 250 (29.48%) 250  (29.48%)
Number Of Links MetaPath 115 88
Specific Links in MetaPath 108 (93.91%) 81  (92.05%)
Shared Links in MetaPath 152 (14.25%) 152  (14.25%)
Number of Shortest Paths 1230188 56529
Length Of Smallest Path 3 3
Average Path Length 26.6297 13.657
Length of Longest Path 53 28
Minimum Path Strength 1.25 0.413333
Average Path Strength 5.88483 5.98084
Maximum Path Strength 23.02 22.3567
Minimum Path Correlation 0.7 0.7
Average Path Correlation 0.979142 0.9098
Maximum Path Correlation 1 0.99
Minimum % Of Corr. Nodes 2.77778 4
Average % Of Corr. Nodes 46.2825 42.8823
Maximum % Of Corr. Nodes 100 100
Minimum Path Hubs % 0 0
Average Path Hubs % 47.5752 36.2269
Maximum Path Hubs % 100 100

Details about the values in these tables can be found in the corresponding documentation page .

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