psnGPCR

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Orange: nodes, hubs and links specific of hcar_off network

Green: nodes, hubs and links shared by both networks

Purple: nodes, hubs and links specific of hcar_on network

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Owner: the name of the network the link belong to or "Shared" if the corresponding link is present in both networks.

Strength: the interaction strength between the two nodes or 0 if the link is not present.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Owner	hcar_off Int. Strength	hcar_on Int. Strength	hcar_off Hub1?	hcar_on Hub1?	hcar_off Hub2?	hcar_on Hub2?	ConSurf1	ConSurf2
1	1x20	7x25	hcar_off	100	0	No	No	No	No	5	4
2	1x22	1x23	hcar_off	100	0	No	No	Yes	No	8	3
3	1x23	7x25	hcar_off	100	0	Yes	No	No	No	3	4
4	1x23	7x29	hcar_off	100	0	Yes	No	No	No	3	4
5	1x24	7x28	hcar_off	100	0	No	No	No	No	5	4
6	1x26	1x30	hcar_off	100	0	No	No	No	No	5	4
7	1x26	7x32	hcar_off	100	0	No	No	No	No	5	1
8	1x27	7x28	hcar_off	100	0	No	No	No	No	3	4
9	1x27	7x31	hcar_off	100	0	No	No	No	No	3	4
10	1x31	2x64	hcar_off	100	0	No	No	Yes	Yes	2	4
11	1x31	Lig	hcar_off	100	0	No	No	Yes	Yes	2	0
12	1x32	1x33	hcar_off	100	0	No	No	No	No	4	5
13	1x34	1x38	hcar_off	100	0	No	No	No	No	5	4
14	1x34	7x36	hcar_off	100	0	No	No	No	No	5	5
15	1x34	7x39	hcar_off	100	0	No	No	No	No	5	5
16	1x35	1x39	hcar_off	100	0	No	No	Yes	No	6	8
17	1x39	7x39	hcar_off	100	0	Yes	No	No	No	8	5
18	1x39	Lig	hcar_off	100	0	Yes	No	Yes	Yes	8	0
19	1x47	2x54	hcar_off	100	0	No	No	No	No	6	5
20	1x50	2x47	hcar_off	100	0	Yes	No	No	No	9	8
21	1x53	7x53	hcar_off	100	0	No	No	Yes	Yes	9	9
22	1x57	1x61	hcar_off	100	0	Yes	No	No	No	7	6
23	1x57	2x40	hcar_off	100	0	Yes	No	No	No	7	8
24	1x57	7x53	hcar_off	100	0	Yes	No	Yes	Yes	7	9
25	1x57	8x50	hcar_off	100	0	Yes	No	Yes	No	7	8
26	1x60	8x57	hcar_off	100	0	No	No	No	No	5	5
27	1x61	8x50	hcar_off	100	0	No	No	Yes	No	6	8
28	2x37	2x39	hcar_off	100	0	No	No	No	No	7	7
29	2x37	2x40	hcar_off	100	0	No	No	No	No	7	8
30	2x37	I2x52	hcar_off	100	0	No	No	Yes	No	7	4
31	2x38	3x49	hcar_off	100	0	No	No	No	No	6	8
32	2x39	3x50	hcar_off	100	0	No	No	No	No	7	9
33	2x42	3x46	hcar_off	100	0	Yes	No	No	No	8	9
34	2x42	4x42	hcar_off	100	0	Yes	No	No	No	8	7
35	2x42	4x45	hcar_off	100	0	Yes	No	No	No	8	6
36	2x43	7x53	hcar_off	100	0	No	No	Yes	Yes	8	9
37	2x45	4x50	hcar_off	100	0	No	No	No	No	9	9
38	2x47	7x53	hcar_off	100	0	No	No	Yes	Yes	8	9
39	2x49	3x35	hcar_off	100	0	No	No	No	No	8	8
40	2x49	3x38	hcar_off	100	0	No	No	Yes	No	8	7
41	2x53	2x54	hcar_off	100	0	Yes	No	No	No	7	5
42	2x53	2x57	hcar_off	100	0	Yes	No	No	No	7	7
43	2x53	7x42	hcar_off	100	0	Yes	No	Yes	Yes	7	7
44	2x53	7x46	hcar_off	100	0	Yes	No	No	No	7	8
45	2x56	3x28	hcar_off	100	0	No	No	No	No	6	5
46	2x59	E1x52	hcar_off	100	0	No	No	Yes	No	7	7
47	2x59	3x24	hcar_off	100	0	No	No	No	No	7	6
48	2x64	7x38	hcar_off	100	0	Yes	Yes	Yes	No	4	5
49	2x64	Lig	hcar_off	100	0	Yes	Yes	Yes	Yes	4	0
50	E1x50	Lig	hcar_off	100	0	Yes	Yes	Yes	Yes	8	0
51	3x24	E1x52	hcar_off	100	0	No	No	Yes	No	6	7
52	3x29	E2x50	hcar_off	100	0	Yes	No	Yes	No	6	9
53	3x30	4x54	hcar_off	100	0	No	Yes	No	No	5	4
54	3x33	4x61	hcar_off	100	0	No	No	No	No	5	3
55	3x33	E2	hcar_off	100	0	No	No	Yes	Yes	5	3
56	3x35	7x46	hcar_off	100	0	No	No	No	No	8	8
57	3x36	3x37	hcar_off	100	0	Yes	No	Yes	No	7	7
58	3x36	6x48	hcar_off	100	0	Yes	No	Yes	No	7	8
59	3x36	6x51	hcar_off	100	0	Yes	No	Yes	No	7	6
60	3x36	7x42	hcar_off	100	0	Yes	No	Yes	Yes	7	7
61	3x37	6x52	hcar_off	100	0	Yes	No	Yes	No	7	8
62	3x37	6x55	hcar_off	100	0	Yes	No	Yes	No	7	6
63	3x38	3x42	hcar_off	100	0	Yes	No	Yes	Yes	7	7
64	3x38	4x50	hcar_off	100	0	Yes	No	No	No	7	9
65	3x39	7x45	hcar_off	100	0	No	No	Yes	No	9	9
66	3x40	5x50	hcar_off	100	0	No	No	No	No	8	9
67	3x40	6x44	hcar_off	100	0	No	No	Yes	No	8	9
68	3x43	6x40	hcar_off	100	0	No	No	No	No	8	8
69	3x43	6x44	hcar_off	100	0	No	No	Yes	No	8	9
70	3x43	7x52	hcar_off	100	0	No	No	Yes	No	8	7
71	3x45	4x45	hcar_off	100	0	No	No	No	No	7	6
72	3x46	6x36	hcar_off	100	0	No	No	No	No	9	8
73	3x47	6x37	hcar_off	100	0	No	No	No	No	9	7
74	3x48	5x57	hcar_off	100	0	No	No	No	No	7	8
75	3x49	I2x52	hcar_off	100	0	No	No	Yes	No	8	4
76	3x50	7x56	hcar_off	100	0	No	No	No	No	9	7
77	3x52	I2x57	hcar_off	100	0	No	Yes	Yes	No	5	6
78	3x53	I2x52	hcar_off	100	0	No	No	Yes	No	7	4
79	3x54	5x64	hcar_off	100	0	Yes	No	No	No	8	4
80	3x56	I2x54	hcar_off	100	0	Yes	Yes	No	No	6	5
81	3x56	I2x57	hcar_off	100	0	Yes	Yes	Yes	No	6	6
82	I2x51	I2x53	hcar_off	100	0	No	No	No	No	5	6
83	I2x52	I2x57	hcar_off	100	0	Yes	No	Yes	No	4	6
84	4x41	I2x56	hcar_off	100	0	Yes	No	No	No	3	2
85	4x41	4x45	hcar_off	100	0	Yes	No	No	No	3	6
86	4x56	5x43	hcar_off	100	0	No	No	Yes	No	5	5
87	4x56	5x46	hcar_off	100	0	No	No	No	No	5	4
88	4x60	5x39	hcar_off	100	0	No	No	No	No	8	6
89	4x61	E2	hcar_off	100	0	No	No	Yes	Yes	3	3
90	4x64	4x68	hcar_off	100	0	No	No	No	No	4	2
91	4x64	E2	hcar_off	100	0	No	No	Yes	Yes	4	3
92	4x68	E2	hcar_off	100	0	No	No	Yes	Yes	2	3
93	4x68	E2x51	hcar_off	100	0	No	No	No	No	2	4
94	E2x50	Lig	hcar_off	100	0	Yes	No	Yes	Yes	9	0
95	E2	E2x52	hcar_off	100	0	Yes	Yes	No	No	3	5
96	7x34	E2x52	hcar_off	100	0	Yes	Yes	No	No	5	5
97	5x39	E2	hcar_off	100	0	No	No	Yes	Yes	6	3
98	6x55	E2	hcar_off	100	0	Yes	No	Yes	Yes	6	3
99	6x59	E2	hcar_off	100	0	No	No	Yes	Yes	5	3
100	6x58	E2	hcar_off	100	0	No	No	Yes	Yes	4	3
101	5x32	5x33	hcar_off	100	0	No	No	No	Yes	2	1
102	5x32	5x35	hcar_off	100	0	No	No	No	No	2	3
103	5x34	5x35	hcar_off	100	0	No	No	No	No	1	3
104	5x36	6x59	hcar_off	100	0	No	No	No	No	4	5
105	5x37	5x41	hcar_off	100	0	No	No	No	No	3	4
106	5x39	5x43	hcar_off	100	0	No	No	Yes	No	6	5
107	5x40	6x55	hcar_off	100	0	No	Yes	Yes	No	5	6
108	5x40	6x56	hcar_off	100	0	No	Yes	No	No	5	5
109	5x41	6x56	hcar_off	100	0	No	No	No	No	4	5
110	5x43	6x55	hcar_off	100	0	Yes	No	Yes	No	5	6
111	5x44	6x52	hcar_off	100	0	No	No	Yes	No	5	8
112	5x44	6x56	hcar_off	100	0	No	No	No	No	5	5
113	5x45	5x49	hcar_off	100	0	No	No	No	No	4	6
114	5x47	6x48	hcar_off	100	0	Yes	Yes	Yes	No	8	8
115	5x51	6x41	hcar_off	100	0	No	No	No	No	6	8
116	5x51	6x45	hcar_off	100	0	No	No	No	No	6	6
117	5x56	5x57	hcar_off	100	0	No	No	No	No	5	8
118	5x58	5x62	hcar_off	100	0	No	No	No	No	8	6
119	5x58	6x34	hcar_off	100	0	No	No	No	No	8	6
120	5x59	5x63	hcar_off	100	0	No	No	No	No	3	3
121	5x62	5x66	hcar_off	100	0	No	No	No	No	6	5
122	5x64	5x68	hcar_off	100	0	No	No	No	No	4	5
123	6x36	7x52	hcar_off	100	0	No	No	Yes	No	8	7
124	6x39	6x43	hcar_off	100	0	No	No	No	No	6	6
125	6x44	7x45	hcar_off	100	0	Yes	No	Yes	No	9	9
126	6x48	6x52	hcar_off	100	0	Yes	No	Yes	No	8	8
127	6x51	6x52	hcar_off	100	0	Yes	No	Yes	No	6	8
128	6x51	6x55	hcar_off	100	0	Yes	No	Yes	No	6	6
129	6x52	6x55	hcar_off	100	0	Yes	No	Yes	No	8	6
130	6x54	6x57	hcar_off	100	0	No	No	No	No	5	5
131	6x57	7x30	hcar_off	100	0	No	No	No	No	5	5
132	6x58	7x31	hcar_off	100	0	No	No	No	No	4	4
133	6x58	7x34	hcar_off	100	0	No	No	Yes	Yes	4	5
134	6x61	7x30	hcar_off	100	0	No	No	No	No	3	5
135	7x35	7x38	hcar_off	100	0	No	No	Yes	No	4	5
136	7x53	8x50	hcar_off	100	0	Yes	Yes	Yes	No	9	8
137	7x54	8x50	hcar_off	100	0	No	Yes	Yes	No	7	8
138	8x49	8x52	hcar_off	100	0	No	No	No	No	6	5
139	8x50	8x54	hcar_off	100	0	Yes	No	No	No	8	7
140	8x51	8x55	hcar_off	100	0	No	No	No	No	8	1
141	2x66	E1x49	hcar_off	0	0	No	No	No	No	4	4
142	3x29	4x65	hcar_off	50	0	Yes	No	No	No	6	4
143	7x56	8x48	hcar_off	0	0	No	No	No	No	7	4
144	1x61	8x53	hcar_off	0	0	No	No	No	No	6	4
145	1x51	1x55	hcar_off	50	0	No	No	No	No	3	4
146	1x30	7x35	hcar_off	0	0	No	No	No	No	4	4
147	7x54	8x51	hcar_off	0	0	No	Yes	No	No	7	8
148	1x58	2x44	hcar_off	50	0	No	No	Yes	Yes	4	6
149	5x61	6x34	hcar_off	0	0	Yes	No	No	No	8	6
150	6x36	7x55	hcar_off	0	0	No	No	No	No	8	7
151	6x47	7x43	hcar_off	0	0	No	No	No	No	9	5
152	1x50	2x51	hcar_off	0	0	Yes	No	No	No	9	7
153	5x65	6x31	hcar_off	0	0	No	No	No	No	8	5
154	3x30	4x62	hcar_off	50	0	No	Yes	No	No	5	4
155	6x51	7x41	hcar_off	0	0	Yes	No	No	No	6	8
156	5x58	6x38	hcar_off	0	0	No	No	No	No	8	4
157	E1x49	E1x51	hcar_off	0	0	No	No	No	No	4	3
158	5x59	5x60	hcar_off	0	0	No	No	No	Yes	3	4
159	6x50	7x37	hcar_off	0	0	No	No	No	No	9	7
160	1x24	1x28	hcar_off	0	0	No	No	No	No	5	4
161	3x54	6x33	hcar_off	0	0	Yes	No	No	No	8	8
162	5x61	6x33	hcar_off	0	0	Yes	No	No	No	8	8
163	5x33	6x63	hcar_off	0	0	No	Yes	No	No	1	2
164	4x41	I2x55	hcar_off	0	0	Yes	No	No	No	3	3
165	1x36	2x61	hcar_off	0	0	No	No	No	No	5	7
166	5x67	5x68	hcar_off	50	0	No	No	No	No	5	5
167	2x41	4x43	hcar_off	0	0	No	No	No	No	6	3
168	1x29	1x33	hcar_off	0	0	No	No	No	No	4	5
169	1x56	8x50	hcar_off	0	0	No	No	Yes	No	7	8
170	3x24	3x27	hcar_off	0	0	No	No	No	No	6	5
171	4x57	4x62	hcar_off	0	0	No	No	No	No	6	4
172	1x52	8x54	hcar_off	0	0	No	No	No	No	5	7
173	3x26	E2	hcar_off	0	0	No	No	Yes	Yes	7	3
174	4x39	4x43	hcar_off	0	0	No	No	No	No	3	3
175	5x34	5x38	hcar_off	0	0	No	No	No	No	1	3
176	6x32	6x35	hcar_off	0	0	No	No	No	No	7	6
177	4x41	4x44	hcar_off	0	0	Yes	No	No	No	3	3
178	8x51	8x52	hcar_off	0	0	No	No	No	No	8	5
179	1x23	7x28	hcar_off	0	0	Yes	No	No	No	3	4
180	1x42	7x47	hcar_off	0	0	No	Yes	No	No	7	8
181	3x21	E2	hcar_off	0	0	No	No	Yes	Yes	8	3
182	4x39	4x40	hcar_off	0	0	No	No	No	No	3	4
183	4x64	4x67	hcar_off	0	0	No	No	No	No	4	5
184	1x20	E3	hcar_off	0	0	No	No	No	Yes	5	7
185	1x36	2x65	hcar_off	0	0	No	No	No	No	5	4
186	2x52	3x31	hcar_off	0	0	No	No	No	No	6	6
187	6x32	6x33	hcar_off	0	0	No	No	No	No	7	8
188	5x38	5x42	hcar_off	0	0	No	No	No	No	3	3
189	1x47	2x55	hcar_off	0	0	No	No	No	No	6	5
190	6x38	6x42	hcar_off	0	0	No	No	No	No	4	5
191	7x26	7x30	hcar_off	0	0	No	No	No	No	1	5
192	3x26	4x66	hcar_off	0	0	No	No	No	No	7	4
193	4x47	4x51	hcar_off	0	0	No	No	No	No	4	4
194	4x51	4x55	hcar_off	0	0	No	No	No	No	4	4
195	1x44	1x48	hcar_off	0	0	No	No	No	No	5	5
196	4x55	4x59	hcar_off	0	0	No	No	No	No	4	4
197	1x43	1x44	hcar_off	0	0	No	No	No	No	7	5
198	6x32	8x47	hcar_off	0	0	No	No	No	No	7	8
199	5x37	6x60	hcar_off	0	0	No	No	No	No	3	4
200	8x55	8x58	hcar_off	0	0	No	No	No	No	1	5
201	2x67	Lig	hcar_off	0	0	No	No	Yes	Yes	4	0
202	1x35	2x64	Shared	100	100	No	No	Yes	Yes	6	4
203	1x38	1x42	Shared	100	50	No	No	No	Yes	4	7
204	1x38	7x39	Shared	100	10	No	No	No	No	4	5
205	1x39	2x57	Shared	100	100	Yes	No	No	No	8	7
206	1x43	1x47	Shared	100	100	No	No	No	No	7	6
207	1x43	2x58	Shared	100	100	No	No	No	No	7	9
208	1x46	2x54	Shared	100	100	No	No	No	No	8	5
209	1x50	2x50	Shared	100	100	Yes	No	No	Yes	9	9
210	1x50	7x50	Shared	100	100	Yes	No	No	No	9	9
211	1x51	2x51	Shared	100	0	No	No	No	No	3	7
212	1x54	2x44	Shared	100	20	No	No	Yes	Yes	7	6
213	1x57	I1	Shared	100	100	Yes	No	No	Yes	7	6
214	1x57	2x44	Shared	100	100	Yes	No	Yes	Yes	7	6
215	2x40	I1	Shared	100	100	No	No	No	Yes	8	6
216	2x44	I1	Shared	100	100	Yes	Yes	No	Yes	6	6
217	2x39	3x49	Shared	100	100	No	No	No	No	7	8
218	2x42	3x45	Shared	100	100	Yes	No	No	No	8	7
219	2x44	2x48	Shared	100	100	Yes	Yes	No	No	6	6
220	2x45	3x42	Shared	100	100	No	No	Yes	Yes	9	7
221	2x45	4x46	Shared	100	100	No	No	No	Yes	9	8
222	2x46	7x49	Shared	100	100	No	No	No	Yes	9	9
223	2x50	7x46	Shared	100	100	No	Yes	No	No	9	8
224	2x50	7x49	Shared	100	100	No	Yes	No	Yes	9	9
225	2x53	3x35	Shared	100	100	Yes	No	No	No	7	8
226	2x59	3x28	Shared	100	20	No	No	No	No	7	5
227	2x60	Lig	Shared	100	100	No	No	Yes	Yes	6	0
228	2x62	2x66	Shared	100	100	No	No	No	No	4	4
229	2x62	E1x52	Shared	100	50	No	No	Yes	No	4	7
230	2x63	E1x50	Shared	100	100	No	No	Yes	Yes	5	8
231	E1x50	E1x52	Shared	100	100	Yes	Yes	Yes	No	8	7
232	3x28	E1x50	Shared	100	100	No	No	Yes	Yes	5	8
233	E1x50	E2x50	Shared	100	100	Yes	Yes	Yes	No	8	9
234	3x22	E2	Shared	100	100	No	No	Yes	Yes	3	3
235	3x25	E2x50	Shared	100	100	No	No	Yes	No	9	9
236	3x29	E2x52	Shared	100	100	Yes	No	No	No	6	5
237	3x29	Lig	Shared	100	100	Yes	No	Yes	Yes	6	0
238	3x30	3x34	Shared	100	100	No	Yes	No	Yes	5	5
239	3x32	7x42	Shared	100	100	No	Yes	Yes	Yes	7	7
240	3x32	Lig	Shared	100	100	No	Yes	Yes	Yes	7	0
241	3x33	4x57	Shared	100	0	No	No	No	No	5	6
242	3x37	5x43	Shared	100	100	Yes	No	Yes	No	7	5
243	3x38	4x53	Shared	100	70	Yes	No	No	No	7	7
244	3x40	6x48	Shared	100	100	No	No	Yes	No	8	8
245	3x41	4x49	Shared	100	100	No	No	No	No	5	7
246	3x42	4x46	Shared	100	100	Yes	Yes	No	Yes	7	8
247	3x42	4x49	Shared	100	100	Yes	Yes	No	No	7	7
248	3x42	4x50	Shared	100	100	Yes	Yes	No	No	7	9
249	3x44	5x54	Shared	100	100	No	No	No	No	7	8
250	3x47	5x54	Shared	100	0	No	No	No	No	9	8
251	3x51	3x55	Shared	100	100	Yes	Yes	No	Yes	8	8
252	3x51	5x57	Shared	100	100	Yes	Yes	No	No	8	8
253	3x51	5x60	Shared	100	100	Yes	Yes	No	Yes	8	4
254	3x51	5x61	Shared	100	5	Yes	Yes	Yes	No	8	8
255	3x54	5x61	Shared	100	100	Yes	No	Yes	No	8	8
256	3x54	5x65	Shared	100	100	Yes	No	No	No	8	8
257	3x55	3x56	Shared	100	100	No	Yes	Yes	Yes	8	6
258	3x55	5x64	Shared	100	50	No	Yes	No	No	8	4
259	I2x54	I2x57	Shared	100	0	No	No	Yes	No	5	6
260	4x52	4x56	Shared	100	5	No	No	No	No	5	5
261	E2	E2	Shared	100	100	Yes	Yes	Yes	Yes	3	3
262	E2	E2x51	Shared	100	100	Yes	Yes	No	No	3	4
263	7x34	E2	Shared	100	100	Yes	Yes	Yes	Yes	5	3
264	5x33	6x62	Shared	100	100	No	Yes	No	No	1	3
265	5x47	6x52	Shared	100	100	Yes	Yes	Yes	No	8	8
266	5x56	5x60	Shared	100	100	No	No	No	Yes	5	4
267	6x39	7x52	Shared	100	100	No	No	Yes	No	6	7
268	6x44	6x48	Shared	100	100	Yes	No	Yes	No	9	8
269	6x48	7x45	Shared	100	100	Yes	No	Yes	No	8	9
270	6x51	7x37	Shared	100	100	Yes	No	No	No	6	7
271	6x54	7x37	Shared	100	100	No	No	No	No	5	7
272	6x55	7x34	Shared	100	100	Yes	No	Yes	Yes	6	5
273	6x62	7x27	Shared	100	100	No	No	No	Yes	3	3
274	7x34	7x38	Shared	100	100	Yes	Yes	Yes	No	5	5
275	7x38	Lig	Shared	100	100	Yes	No	Yes	Yes	5	0
276	7x42	Lig	Shared	100	100	Yes	Yes	Yes	Yes	7	0
277	7x45	7x49	Shared	100	100	Yes	No	No	Yes	9	9
278	3x37	5x461	Shared	0	100	Yes	No	No	Yes	7	5
279	6x61	7x27	Shared	0	100	No	No	No	Yes	3	3
280	2x41	4x42	Shared	50	100	No	No	No	No	6	7
281	6x54	7x33	Shared	0	0	No	No	No	No	5	5
282	1x42	7x43	Shared	50	100	No	Yes	No	No	7	5
283	5x47	6x49	Shared	0	100	Yes	Yes	No	Yes	8	6
284	7x51	7x52	Shared	0	5	No	No	Yes	No	6	7
285	5x47	5x48	Shared	0	100	Yes	Yes	No	No	8	4
286	5x47	5x51	Shared	0	100	Yes	Yes	No	No	8	6
287	6x49	6x50	Shared	0	10	No	Yes	No	No	6	9
288	5x55	6x41	Shared	0	0	No	No	No	No	5	8
289	5x49	5x50	Shared	0	100	No	No	No	No	6	9
290	6x50	7x40	Shared	0	100	No	No	No	No	9	8
291	1x55	1x59	Shared	0	100	No	No	No	No	4	4
292	2x56	3x31	Shared	0	100	No	No	No	No	6	6
293	3x44	5x53	Shared	0	100	No	No	No	No	7	6
294	5x61	6x37	Shared	0	100	Yes	No	No	No	8	7
295	6x49	6x53	Shared	0	0	No	Yes	No	No	6	6
296	7x43	7x48	Shared	0	100	No	No	No	No	5	5
297	3x22	3x23	Shared	0	60	No	No	No	No	3	3
298	4x38	4x40	Shared	0	10	No	No	No	No	7	4
299	1x45	7x47	Shared	0	100	No	No	No	No	5	8
300	1x39	2x61	Shared	0	100	Yes	No	No	No	8	7
301	1x56	1x60	Shared	0	100	No	No	No	No	7	5
302	1x40	2x61	Shared	0	70	No	No	No	No	5	7
303	4x59	4x60	Shared	0	100	No	No	No	No	4	8
304	6x42	6x46	Shared	0	5	No	No	No	No	5	6
305	1x41	1x45	Shared	0	100	No	No	No	No	5	5
306	3x56	I2x50	Shared	0	0	Yes	Yes	No	No	6	8
307	I2x50	I2x51	Shared	0	100	No	No	No	No	8	5
308	1x49	7x50	Shared	0	70	No	No	No	No	7	9
309	NT	NT	hcar_on	0	100	No	Yes	No	Yes	0	0
310	E3	NT	hcar_on	0	100	No	Yes	No	Yes	7	0
311	7x24	NT	hcar_on	0	100	No	No	No	Yes	0	0
312	E2	NT	hcar_on	0	100	Yes	Yes	No	Yes	3	0
313	5x34	NT	hcar_on	0	100	No	No	No	Yes	1	0
314	5x36	NT	hcar_on	0	100	No	No	No	Yes	4	0
315	1x26	NT	hcar_on	0	100	No	No	No	Yes	5	0
316	1x26	7x31	hcar_on	0	100	No	No	No	No	5	4
317	1x27	2x67	hcar_on	0	100	No	No	No	No	3	4
318	1x27	E2	hcar_on	0	100	No	No	Yes	Yes	3	3
319	1x31	1x35	hcar_on	0	100	No	No	No	No	2	6
320	1x31	7x32	hcar_on	0	100	No	No	No	No	2	1
321	1x36	1x37	hcar_on	0	100	No	No	No	No	5	5
322	1x43	2x57	hcar_on	0	100	No	No	No	No	7	7
323	1x52	7x55	hcar_on	0	100	No	No	No	No	5	7
324	1x54	2x51	hcar_on	0	100	No	No	No	No	7	7
325	1x57	7x54	hcar_on	0	100	Yes	No	No	Yes	7	7
326	1x58	1x59	hcar_on	0	100	No	No	No	No	4	4
327	I1	I1	hcar_on	0	100	No	Yes	No	Yes	6	6
328	2x38	I2x57	hcar_on	0	100	No	No	Yes	No	6	6
329	2x43	7x54	hcar_on	0	100	No	No	No	Yes	8	7
330	2x46	7x53	hcar_on	0	100	No	No	Yes	Yes	9	9
331	2x46	7x54	hcar_on	0	100	No	No	No	Yes	9	7
332	2x47	7x54	hcar_on	0	100	No	No	No	Yes	8	7
333	2x50	3x39	hcar_on	0	100	No	Yes	No	No	9	9
334	2x52	3x35	hcar_on	0	100	No	No	No	No	6	8
335	2x57	7x42	hcar_on	0	100	No	No	Yes	Yes	7	7
336	2x60	2x64	hcar_on	0	100	No	No	Yes	Yes	6	4
337	2x63	E1	hcar_on	0	100	No	No	No	No	5	0
338	7x35	E1	hcar_on	0	100	No	No	No	No	4	0
339	E1x49	E2	hcar_on	0	100	No	No	Yes	Yes	4	3
340	3x25	E1x50	hcar_on	0	100	No	No	Yes	Yes	9	8
341	3x21	3x24	hcar_on	0	100	No	No	No	No	8	6
342	3x22	3x26	hcar_on	0	100	No	No	No	No	3	7
343	3x23	3x24	hcar_on	0	100	No	No	No	No	3	6
344	3x25	E2	hcar_on	0	100	No	No	Yes	Yes	9	3
345	3x30	4x57	hcar_on	0	100	No	Yes	No	No	5	6
346	3x30	4x61	hcar_on	0	100	No	Yes	No	No	5	3
347	3x34	4x53	hcar_on	0	100	No	Yes	No	No	5	7
348	3x34	4x54	hcar_on	0	100	No	Yes	No	No	5	4
349	3x36	5x461	hcar_on	0	100	Yes	No	No	Yes	7	5
350	3x36	7x41	hcar_on	0	100	Yes	No	No	No	7	8
351	3x36	Lig	hcar_on	0	100	Yes	No	Yes	Yes	7	0
352	3x37	4x56	hcar_on	0	100	Yes	No	No	No	7	5
353	3x40	5x461	hcar_on	0	100	No	No	No	Yes	8	5
354	3x43	7x53	hcar_on	0	100	No	No	Yes	Yes	8	9
355	3x44	5x50	hcar_on	0	100	No	No	No	No	7	9
356	3x49	3x53	hcar_on	0	100	No	No	No	No	8	7
357	3x50	7x53	hcar_on	0	100	No	No	Yes	Yes	9	9
358	3x51	3x52	hcar_on	0	100	Yes	Yes	No	Yes	8	5
359	3x51	3x56	hcar_on	0	100	Yes	Yes	Yes	Yes	8	6
360	3x52	I2x52	hcar_on	0	100	No	Yes	Yes	No	5	4
361	3x52	I2x54	hcar_on	0	100	No	Yes	No	No	5	5
362	3x53	I2x55	hcar_on	0	100	No	No	No	No	7	3
363	3x55	5x60	hcar_on	0	100	No	Yes	No	Yes	8	4
364	4x38	4x41	hcar_on	0	100	No	No	Yes	No	7	3
365	4x56	5x39	hcar_on	0	100	No	No	No	No	5	6
366	4x59	5x39	hcar_on	0	100	No	No	No	No	4	6
367	4x59	5x40	hcar_on	0	100	No	No	No	Yes	4	5
368	4x60	5x40	hcar_on	0	100	No	No	No	Yes	8	5
369	4x63	E2	hcar_on	0	100	No	No	Yes	Yes	5	3
370	E2x51	Lig	hcar_on	0	100	No	No	Yes	Yes	4	0
371	5x40	E2x52	hcar_on	0	100	No	Yes	No	No	5	5
372	E2x52	Lig	hcar_on	0	100	No	No	Yes	Yes	5	0
373	5x40	E2	hcar_on	0	100	No	Yes	Yes	Yes	5	3
374	5x44	E2	hcar_on	0	100	No	No	Yes	Yes	5	3
375	E2	Lig	hcar_on	0	100	Yes	Yes	Yes	Yes	3	0
376	5x33	6x58	hcar_on	0	100	No	Yes	No	No	1	4
377	5x33	7x27	hcar_on	0	100	No	Yes	No	Yes	1	3
378	5x35	E3	hcar_on	0	100	No	No	No	Yes	3	7
379	5x40	5x43	hcar_on	0	100	No	Yes	Yes	No	5	5
380	5x41	6x55	hcar_on	0	100	No	No	Yes	No	4	6
381	5x41	6x59	hcar_on	0	100	No	No	No	No	4	5
382	5x44	5x461	hcar_on	0	100	No	No	No	Yes	5	5
383	5x44	6x51	hcar_on	0	100	No	No	Yes	No	5	6
384	5x47	6x44	hcar_on	0	100	Yes	Yes	Yes	No	8	9
385	5x54	6x44	hcar_on	0	100	No	No	Yes	No	8	9
386	5x58	6x37	hcar_on	0	100	No	No	No	No	8	7
387	5x62	6x34	hcar_on	0	100	No	No	No	No	6	6
388	5x66	I3	hcar_on	0	100	No	No	No	Yes	5	4
389	I3	I3	hcar_on	0	100	No	Yes	No	Yes	4	4
390	6x32	6x36	hcar_on	0	100	No	No	No	No	7	8
391	6x32	8x48	hcar_on	0	100	No	No	No	No	7	4
392	6x36	7x56	hcar_on	0	100	No	No	No	No	8	7
393	6x40	7x53	hcar_on	0	100	No	No	Yes	Yes	8	9
394	6x47	7x45	hcar_on	0	100	No	No	Yes	No	9	9
395	6x54	7x34	hcar_on	0	100	No	No	Yes	Yes	5	5
396	6x57	6x61	hcar_on	0	100	No	No	No	No	5	3
397	6x58	7x30	hcar_on	0	100	No	No	No	No	4	5
398	6x60	6x64	hcar_on	0	100	No	No	No	No	4	0
399	E3	E3	hcar_on	0	100	No	Yes	No	Yes	7	7
400	7x23	7x25	hcar_on	0	100	No	No	No	No	0	4
401	7x25	7x28	hcar_on	0	100	No	No	No	No	4	4
402	7x26	7x27	hcar_on	0	100	No	No	No	Yes	1	3
403	7x49	7x53	hcar_on	0	100	No	Yes	Yes	Yes	9	9
404	1x30	1x34	hcar_on	0	100	No	No	No	No	4	5
405	1x36	2x64	hcar_on	0	100	No	No	Yes	Yes	5	4
406	1x41	1x42	hcar_on	0	100	No	No	No	Yes	5	7
407	2x43	3x46	hcar_on	0	100	No	No	No	No	8	9
408	2x64	7x35	hcar_on	0	100	Yes	Yes	No	No	4	4
409	2x66	E1x51	hcar_on	0	100	No	No	No	No	4	3
410	E1x50	E2	hcar_on	0	100	Yes	Yes	Yes	Yes	8	3
411	3x46	3x50	hcar_on	0	100	No	No	No	No	9	9
412	3x52	3x56	hcar_on	0	100	No	Yes	Yes	Yes	5	6
413	5x33	7x31	hcar_on	0	100	No	Yes	No	No	1	4
414	5x35	6x62	hcar_on	0	100	No	No	No	No	3	3
415	5x38	5x41	hcar_on	0	100	No	No	No	No	3	4
416	5x62	6x37	hcar_on	0	100	No	No	No	No	6	7
417	5x62	6x38	hcar_on	0	100	No	No	No	No	6	4
418	5x63	5x67	hcar_on	0	100	No	No	No	No	3	5
419	7x35	Lig	hcar_on	0	100	No	No	Yes	Yes	4	0
420	7x43	7x47	hcar_on	0	100	No	No	No	No	5	8
421	2x62	E1x51	hcar_on	0	100	No	No	No	No	4	3
422	5x38	5x40	hcar_on	0	100	No	No	No	Yes	3	5
423	7x28	NT	hcar_on	0	100	No	No	No	Yes	4	0
424	6x26	6x27	hcar_on	0	100	No	No	No	No	0	0
425	E1	NT	hcar_on	0	100	No	No	No	Yes	0	0
426	1x33	NT	hcar_on	0	100	No	No	No	Yes	5	0
427	6x27	6x29	hcar_on	0	50	No	No	No	No	0	0
428	6x26	I3	hcar_on	0	50	No	No	No	Yes	0	4
429	2x44	2x45	hcar_on	0	55	Yes	Yes	No	No	6	9
430	1x35	7x36	hcar_on	0	55	No	No	No	No	6	5
431	1x25	E2	hcar_on	0	50	No	No	Yes	Yes	5	3
432	8x47	8x48	hcar_on	0	60	No	No	No	No	8	4
433	2x54	7x46	hcar_on	0	55	No	No	No	No	5	8
434	3x34	4x50	hcar_on	0	65	No	Yes	No	No	5	9
435	6x35	6x36	hcar_on	0	50	No	No	No	No	6	8
436	5x65	I3	hcar_on	0	20	No	No	No	Yes	8	4
437	1x55	1x60	hcar_on	0	50	No	No	No	No	4	5
438	6x64	E3	hcar_on	0	20	No	No	No	Yes	0	7
439	2x41	I1	hcar_on	0	50	No	No	No	Yes	6	6
440	2x53	3x32	hcar_on	0	60	Yes	No	No	Yes	7	7
441	4x45	4x49	hcar_on	0	10	No	No	No	No	6	7
442	5x51	5x55	hcar_on	0	50	No	No	No	No	6	5
443	2x37	I1	hcar_on	0	50	No	No	No	Yes	7	6
444	6x63	6x64	hcar_on	0	60	No	No	No	No	2	0
445	1x53	7x54	hcar_on	0	20	No	No	No	Yes	9	7
446	3x26	4x64	hcar_on	0	15	No	No	No	No	7	4
447	1x42	7x42	hcar_on	0	50	No	Yes	Yes	Yes	7	7
448	1x28	7x32	hcar_on	0	50	No	No	No	No	4	1
449	2x49	4x50	hcar_on	0	10	No	No	No	No	8	9
450	1x48	1x49	hcar_on	0	5	No	No	No	No	5	7
451	6x43	7x48	hcar_on	0	50	No	No	No	No	6	5
452	2x56	3x32	hcar_on	0	50	No	No	No	Yes	6	7
453	7x50	7x55	hcar_on	0	20	No	No	No	No	9	7
454	4x41	I2x57	hcar_on	0	50	Yes	No	Yes	No	3	6
455	I2x52	I2x55	hcar_on	0	50	Yes	No	No	No	4	3
456	6x45	6x49	hcar_on	0	5	No	No	No	Yes	6	6
457	2x41	4x39	hcar_on	0	50	No	No	No	No	6	3
458	2x42	4x46	hcar_on	0	5	Yes	No	No	Yes	8	8
459	3x48	3x52	hcar_on	0	5	No	No	No	Yes	7	5
460	6x52	6x56	hcar_on	0	0	Yes	No	No	No	8	5
461	5x45	6x56	hcar_on	0	5	No	No	No	No	4	5
462	5x65	6x30	hcar_on	0	15	No	No	No	No	8	0
463	2x51	2x55	hcar_on	0	50	No	No	No	No	7	5
464	1x30	7x32	hcar_on	0	50	No	No	No	No	4	1
465	1x44	1x45	hcar_on	0	20	No	No	No	No	5	5
466	2x38	4x42	hcar_on	0	10	No	No	No	No	6	7
467	4x54	4x55	hcar_on	0	10	No	No	No	No	4	4
468	7x52	7x53	hcar_on	0	20	Yes	No	Yes	Yes	7	9
469	3x30	4x58	hcar_on	0	5	No	Yes	No	No	5	0
470	2x65	2x66	hcar_on	0	20	No	No	No	No	4	4
471	1x29	2x67	hcar_on	0	50	No	No	No	No	4	4
472	1x32	2x67	hcar_on	0	50	No	No	No	No	4	4
473	2x40	8x47	hcar_on	0	0	No	No	No	No	8	8
474	6x28	6x30	hcar_on	0	0	No	No	No	No	0	0
475	5x60	5x63	hcar_on	0	20	No	Yes	No	No	4	3
476	6x31	I3	hcar_on	0	15	No	No	No	Yes	5	4
477	5x32	E2x51	hcar_on	0	15	No	No	No	No	2	4
478	6x46	6x47	hcar_on	0	0	No	No	No	No	6	9
479	1x60	8x53	hcar_on	0	5	No	No	No	No	5	4
480	4x40	4x44	hcar_on	0	15	No	No	No	No	4	3
481	4x48	4x52	hcar_on	0	10	No	No	No	No	3	5
482	1x52	1x56	hcar_on	0	10	No	No	No	No	5	7
483	5x51	5x52	hcar_on	0	0	No	No	No	No	6	3
484	2x40	8x49	hcar_on	0	5	No	No	No	No	8	6
485	5x37	5x42	hcar_on	0	5	No	No	No	No	3	3
486	8x49	8x50	hcar_on	0	10	No	No	Yes	No	6	8
487	5x37	6x59	hcar_on	0	10	No	No	No	No	3	5
488	4x51	4x54	hcar_on	0	10	No	No	No	No	4	4
489	7x29	7x30	hcar_on	0	5	No	No	No	No	4	5
490	5x46	5x49	hcar_on	0	5	No	No	No	No	4	6
491	3x52	I2x56	hcar_on	0	5	No	Yes	No	No	5	2
492	3x23	3x27	hcar_on	0	0	No	No	No	No	3	5
493	4x58	4x62	hcar_on	0	0	No	No	No	No	0	4
494	I2x52	I2x53	hcar_on	0	0	Yes	No	No	No	4	6
495	4x43	4x46	hcar_on	0	0	No	No	No	Yes	3	8
496	4x46	4x47	hcar_on	0	0	No	Yes	No	No	8	4
497	5x58	5x59	hcar_on	0	0	No	No	No	No	8	3
498	6x30	6x33	hcar_on	0	0	No	No	No	No	0	8
499	8x56	8x57	hcar_on	0	0	No	No	No	No	4	5
500	8x50	8x51	hcar_on	0	0	Yes	No	No	No	8	8
501	1x56	8x57	hcar_on	0	0	No	No	No	No	7	5
502	8x54	8x55	hcar_on	0	0	No	No	No	No	7	1

Orange: nodes, hubs and links specific of hcar_off network

Green: nodes, hubs and links shared by both networks

Purple: nodes, hubs and links specific of hcar_on network

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Owner: the name of the network the hub belong to or "Shared" if the corresponding hub is present in both networks.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub in the corresponding network.

Num Of Links: the number of links of the corresponding hub in the corresponding network.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Owner	hcar_off Avg Int. Strength	hcar_on Avg Int. Strength	hcar_off Num Of Links	hcar_on Num Of Links	ConSurf
1	1x23	hcar_off	0	0	4	0	3
2	1x39	hcar_off	100	0	5	2	8
3	1x50	hcar_off	0	0	4	2	9
4	1x57	hcar_off	100	0	6	3	7
5	2x42	hcar_off	100	0	4	2	8
6	2x53	hcar_off	100	0	5	2	7
7	E1x52	hcar_off	100	0	4	2	7
8	3x29	hcar_off	50	0	4	2	6
9	3x36	hcar_off	100	0	4	3	7
10	3x37	hcar_off	100	15	5	3	7
11	3x38	hcar_off	50	0	4	1	7
12	3x54	hcar_off	0	0	4	2	8
13	I2x52	hcar_off	100	0	4	3	4
14	I2x57	hcar_off	100	0	4	3	6
15	4x41	hcar_off	0	0	4	2	3
16	E2x50	hcar_off	50	0	4	2	9
17	5x43	hcar_off	100	0	4	2	5
18	5x61	hcar_off	0	0	5	3	8
19	6x44	hcar_off	100	0	4	3	9
20	6x48	hcar_off	100	45	6	3	8
21	6x51	hcar_off	100	0	5	2	6
22	6x52	hcar_off	100	0	6	2	8
23	6x55	hcar_off	100	40	7	2	6
24	7x38	hcar_off	100	0	4	2	5
25	7x45	hcar_off	100	0	4	3	9
26	7x52	hcar_off	0	0	4	3	7
27	8x50	hcar_off	100	0	6	2	8
28	2x44	Shared	100	50	5	5	6
29	2x64	Shared	100	95	4	4	4
30	E1x50	Shared	100	95	5	6	8
31	3x42	Shared	100	50	5	4	7
32	3x51	Shared	100	95	4	6	8
33	3x56	Shared	0	0	4	4	6
34	E2	Shared	100	100	16	15	3
35	5x47	Shared	0	90	5	5	8
36	7x34	Shared	100	50	5	4	5
37	7x42	Shared	50	0	4	4	7
38	7x53	Shared	100	95	5	6	9
39	Lig	Shared	100	95	11	10	0
40	NT	hcar_on	0	100	0	11	0
41	1x42	hcar_on	0	0	3	4	7
42	I1	hcar_on	0	85	3	7	6
43	2x50	hcar_on	0	50	3	4	9
44	3x30	hcar_on	0	0	3	4	5
45	3x32	hcar_on	0	0	2	4	7
46	3x34	hcar_on	0	30	1	4	5
47	3x52	hcar_on	0	15	1	6	5
48	3x55	hcar_on	0	30	3	4	8
49	4x46	hcar_on	0	0	2	5	8
50	5x33	hcar_on	0	50	3	4	1
51	5x40	hcar_on	0	50	2	6	5
52	5x461	hcar_on	0	10	1	4	5
53	5x60	hcar_on	0	0	3	4	4
54	I3	hcar_on	0	25	0	6	4
55	6x49	hcar_on	0	0	3	4	6
56	E3	hcar_on	0	25	1	5	7
57	7x27	hcar_on	0	85	2	4	3
58	7x49	hcar_on	50	90	3	4	9
59	7x54	hcar_on	0	95	2	5	7

Orange: nodes, hubs and links specific of hcar_off network

Green: nodes, hubs and links shared by both networks

Purple: nodes, hubs and links specific of hcar_on network

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Owner: the name of the network the link belong to or "Shared" if the corresponding link is present in both networks.

Recurrence: the relative Recurrence in the filtered pool of shortest paths.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Owner	hcar_off Recurrence	hcar_on Recurrence	hcar_off Hub1?	hcar_on Hub1?	hcar_off Hub2?	hcar_on Hub2?	ConSurf1	ConSurf2
1	1x23	7x28	hcar_off	12.8629	0	Yes	No	No	No	3	4
2	1x27	7x28	hcar_off	19.1998	0	No	No	No	No	3	4
3	1x27	7x31	hcar_off	20.8565	0	No	No	No	No	3	4
4	6x58	7x31	hcar_off	22.7624	0	No	No	No	No	4	4
5	6x58	7x34	hcar_off	15.6092	0	No	No	Yes	Yes	4	5
6	7x34	7x38	hcar_off	17.5191	2.29999	Yes	Yes	Yes	No	5	5
7	7x38	Lig	hcar_off	18.2147	3.05916	Yes	No	Yes	Yes	5	0
8	1x39	Lig	hcar_off	12.0466	0	Yes	No	Yes	Yes	8	0
9	1x39	7x39	hcar_off	13.1765	0	Yes	No	No	No	8	5
10	2x53	7x42	hcar_off	45.2312	0	Yes	No	Yes	Yes	7	7
11	2x53	2x54	hcar_off	10.8524	0	Yes	No	No	No	7	5
12	6x55	E2	hcar_off	26.8758	0	Yes	No	Yes	Yes	6	3
13	6x52	6x55	hcar_off	32.7463	0	Yes	No	Yes	No	8	6
14	6x48	6x52	hcar_off	47.6196	0	Yes	No	Yes	No	8	8
15	6x55	7x34	hcar_off	12.7986	6.86402	Yes	No	Yes	Yes	6	5
16	2x53	7x46	hcar_off	37.2095	0	Yes	No	No	No	7	8
17	2x50	7x46	hcar_off	41.9984	4.05193	No	Yes	No	No	9	8
18	1x50	2x47	hcar_off	94.0893	0	Yes	No	No	No	9	8
19	2x47	7x53	hcar_off	93.1202	0	No	No	Yes	Yes	8	9
20	1x57	7x53	hcar_off	74.2019	0	Yes	No	Yes	Yes	7	9
21	7x53	8x50	hcar_off	16.2686	0	Yes	Yes	Yes	No	9	8
22	1x57	2x40	hcar_off	68.7455	0	Yes	No	No	No	7	8
23	2x37	2x40	hcar_off	68.8138	0	No	No	No	No	7	8
24	2x37	I2x52	hcar_off	61.1178	0	No	No	Yes	No	7	4
25	3x43	6x44	hcar_off	28.0177	0	No	No	Yes	No	8	9
26	3x43	7x52	hcar_off	25.5368	0	No	No	Yes	No	8	7
27	6x36	7x52	hcar_off	20.5871	0	No	No	Yes	No	8	7
28	3x46	6x36	hcar_off	18.1825	0	No	No	No	No	9	8
29	2x42	3x46	hcar_off	16.8838	0	Yes	No	No	No	8	9
30	2x53	3x35	hcar_off	10.9208	2.77166	Yes	No	No	No	7	8
31	2x49	3x35	hcar_off	14.6723	0	No	No	No	No	8	8
32	2x49	3x38	hcar_off	13.2409	0	No	No	Yes	No	8	7
33	E1x50	Lig	hcar_off	17.7282	0	Yes	Yes	Yes	Yes	8	0
34	E1x50	E1x52	hcar_off	10.5629	6.84605	Yes	Yes	Yes	No	8	7
35	3x36	3x37	hcar_off	15.4564	0	Yes	No	Yes	No	7	7
36	3x36	6x51	hcar_off	23.8641	0	Yes	No	Yes	No	7	6
37	5x39	5x43	hcar_off	12.8589	0	No	No	Yes	No	6	5
38	I2x52	I2x57	hcar_off	57.4548	0	Yes	No	Yes	No	4	6
39	3x56	I2x57	hcar_off	53.6751	0	Yes	Yes	Yes	No	6	6
40	3x55	3x56	hcar_off	48.8983	2.22362	No	Yes	Yes	Yes	8	6
41	3x51	3x55	hcar_off	34.5195	2.32694	Yes	Yes	No	Yes	8	8
42	3x55	5x64	hcar_off	13.3092	1.95409	No	Yes	No	No	8	4
43	4x60	5x39	hcar_off	15.8665	0	No	No	No	No	8	6
44	6x51	7x37	hcar_off	32.887	2.72674	Yes	No	No	No	6	7
45	6x54	7x37	hcar_off	30.2493	2.25057	No	No	No	No	5	7
46	6x54	6x57	hcar_off	26.2686	0	No	No	No	No	5	5
47	6x57	7x30	hcar_off	24.2622	0	No	No	No	No	5	5
48	6x61	7x30	hcar_off	20.6152	0	No	No	No	No	3	5
49	6x61	7x27	hcar_off	18.5887	4.97282	No	No	No	Yes	3	3
50	6x62	7x27	hcar_off	16.5581	4.95485	No	No	No	Yes	3	3
51	5x33	6x62	hcar_off	14.5195	0.116796	No	Yes	No	No	1	3
52	5x32	5x33	hcar_off	10.4101	0	No	No	No	Yes	2	1
53	5x61	6x34	hcar_off	10.4664	0	Yes	No	No	No	8	6
54	4x59	4x60	hcar_off	13.2167	0.0179686	No	No	No	No	4	8
55	3x36	7x42	hcar_off	36.1319	0	Yes	No	Yes	Yes	7	7
56	3x36	6x48	hcar_off	26.3731	0	Yes	No	Yes	No	7	8
57	6x51	6x52	hcar_off	10.6353	0	Yes	No	Yes	No	6	8
58	3x37	5x43	hcar_off	14.9618	7.34918	Yes	No	Yes	No	7	5
59	6x44	7x45	hcar_off	10.965	0	Yes	No	Yes	No	9	9
60	7x42	Lig	Shared	34.4712	22.9864	Yes	Yes	Yes	Yes	7	0
61	6x48	7x45	Shared	53.1403	97.7494	Yes	No	Yes	No	8	9
62	7x45	7x49	Shared	63.1122	96.8869	Yes	No	No	Yes	9	9
63	2x50	7x49	Shared	62.694	23.485	No	Yes	No	Yes	9	9
64	1x50	2x50	Shared	100	17.3981	Yes	No	No	Yes	9	9
65	6x44	6x48	Shared	19.4129	27.784	Yes	No	Yes	No	9	8
66	3x51	5x61	Shared	23.8721	22.4294	Yes	Yes	Yes	No	8	8
67	1x31	1x35	hcar_on	0	12.1288	No	No	No	No	2	6
68	1x35	2x64	hcar_on	0.763973	17.1151	No	No	Yes	Yes	6	4
69	2x64	7x35	hcar_on	0	12.9015	Yes	Yes	No	No	4	4
70	E2	Lig	hcar_on	0	13.8673	Yes	Yes	Yes	Yes	3	0
71	E2	NT	hcar_on	0	29.6213	Yes	Yes	No	Yes	3	0
72	1x42	7x42	hcar_on	0	13.5169	No	Yes	Yes	Yes	7	7
73	3x40	6x48	hcar_on	5.01407	100	No	No	Yes	No	8	8
74	3x40	5x461	hcar_on	0	99.9865	No	No	No	Yes	8	5
75	5x44	5x461	hcar_on	0	53.6948	No	No	No	Yes	5	5
76	5x44	E2	hcar_on	0	51.552	No	No	Yes	Yes	5	3
77	1x50	7x50	hcar_on	3.02774	16.1538	Yes	No	No	No	9	9
78	1x52	7x55	hcar_on	0	11.0732	No	No	No	No	5	7
79	7x50	7x55	hcar_on	0	12.3669	No	No	No	No	9	7
80	1x57	2x44	hcar_on	5.93888	28.6196	Yes	No	Yes	Yes	7	6
81	1x57	7x54	hcar_on	0	85.6386	Yes	No	No	Yes	7	7
82	2x46	7x54	hcar_on	0	87.0356	No	No	No	Yes	9	7
83	2x46	7x49	hcar_on	1.48774	84.6458	No	No	No	Yes	9	9
84	2x40	I1	hcar_on	0.997185	11.9851	No	No	No	Yes	8	6
85	1x57	I1	hcar_on	1.10173	56.6731	Yes	No	No	Yes	7	6
86	2x38	4x42	hcar_on	0	52.994	No	No	No	No	6	7
87	2x41	4x42	hcar_on	6.91194	53.9374	No	No	No	No	6	7
88	2x41	I1	hcar_on	0	55.7971	No	No	No	Yes	6	6
89	2x38	I2x57	hcar_on	0	52.0147	No	No	Yes	No	6	6
90	3x52	I2x54	hcar_on	0	46.112	No	Yes	No	No	5	5
91	I2x54	I2x57	hcar_on	1.37113	47.1183	No	No	Yes	No	5	6
92	2x44	2x45	hcar_on	0	30.1918	Yes	Yes	No	No	6	9
93	2x45	3x42	hcar_on	1.48774	22.7977	No	No	Yes	Yes	9	7
94	E1x50	E2	hcar_on	0	12.1513	Yes	Yes	Yes	Yes	8	3
95	5x40	E2	hcar_on	0	11.9896	No	Yes	Yes	Yes	5	3
96	3x34	4x50	hcar_on	0	15.7899	No	Yes	No	No	5	9
97	3x42	4x50	hcar_on	0.0120627	18.2966	Yes	Yes	No	No	7	9
98	3x36	Lig	hcar_on	0	37.9992	Yes	No	Yes	Yes	7	0
99	3x37	5x461	hcar_on	2.19944	12.3355	Yes	No	No	Yes	7	5
100	3x51	3x52	hcar_on	0	31.0768	Yes	Yes	No	Yes	8	5
101	3x54	5x61	hcar_on	0.390028	14.1054	Yes	No	Yes	No	8	8
102	3x54	5x65	hcar_on	2.79453	12.8386	Yes	No	No	No	8	8
103	E3	NT	hcar_on	0	11.4326	No	Yes	No	Yes	7	0
104	1x26	7x31	hcar_on	0	10.4533	No	No	No	No	5	4
105	1x26	NT	hcar_on	0	11.3966	No	No	No	Yes	5	0
106	5x38	5x40	hcar_on	0	10.5341	No	No	No	Yes	3	5
107	7x34	E2	hcar_on	5.9228	10.0175	Yes	Yes	Yes	Yes	5	3
108	5x41	6x59	hcar_on	0	10.2107	No	No	No	No	4	5
109	5x47	6x44	hcar_on	0	18.2337	Yes	Yes	Yes	No	8	9
110	2x60	2x64	hcar_on	0	11.4191	No	No	Yes	Yes	6	4
111	2x60	Lig	hcar_on	1.24246	12.3714	No	No	Yes	Yes	6	0
112	7x35	Lig	hcar_on	0	12.9779	No	No	Yes	Yes	4	0
113	3x36	5x461	hcar_on	0	38.417	Yes	No	No	Yes	7	5

Here, those paths that begin and end at given residue pair(s) or that pass through a residue are used to generate a novel metapath. Such a path filtering is particularly recommended if some information on allosteric residues is available. The selection syntax for a residue pair ("Pairs") is C:C:c534,A:A:?600 (the lower-case "c" stands for cytosine and "?" indicates any non standard amino acid or nucleotide residue). Selection of more than one apical residue pair has the following syntax: C:C:c534,A:A:?600,C:C:c534,A:A:E41. Only one residue can be selected as a tail ("Tail"). For midway residue(s), each residue must be separated by a comma as well e.g. A:A:?600,A:A:E41.

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Node1	Node2	Owner	Net1LinkStrength	Net2LinkStrength	Comm1	Comm2	Node1Shell	Node2Shell
1x31	2x64	hcar_off	11.785	0	1	0	1	1
1x31	Lig	hcar_off	5.2	0	1	0	1	0
1x35	1x39	hcar_off	4.69	0	0	0	2	1
1x35	2x64	Shared	10.55	9.73	0	0	2	1
1x39	2x57	Shared	7.03	4.982	0	0	1	2
1x39	7x39	hcar_off	11.13	0	0	0	1	2
1x39	Lig	hcar_off	6.675	0	0	0	1	0
2x53	2x57	hcar_off	9.74	0	1	0	2	2
2x53	7x42	hcar_off	15	0	1	0	2	1
2x56	3x28	hcar_off	5.85	0	0	0	2	2
2x60	Lig	Shared	10.625	5.56	0	0	1	0
2x63	E1x50	Shared	4.94	7.843	0	0	2	1
2x64	7x38	hcar_off	5.14	0	1	0	1	1
2x64	Lig	hcar_off	17.435	0	1	0	1	0
E1x50	E1x52	Shared	12.54	8.466	1	1	1	2
3x28	E1x50	Shared	4.52	3.61	0	0	2	1
E1x50	E2x50	Shared	9.14	7.8375	1	1	1	1
E1x50	Lig	hcar_off	10.165	0	1	1	1	0
3x22	E2	Shared	6.8	6.684	1	1	2	1
3x25	E2x50	Shared	7.28	7.098	0	1	2	1
3x29	E2x50	hcar_off	7.66	0	1	1	1	1
3x29	E2x52	Shared	5.96	5.406	1	1	1	1
3x29	Lig	Shared	27.39	8.265	1	1	1	0
3x32	7x42	Shared	7.31	5.238	1	1	1	1
3x32	Lig	Shared	11.995	14.6955	1	1	1	0
3x33	4x61	hcar_off	11.165	0	1	0	2	2
3x33	E2	hcar_off	8.71	0	1	0	2	1
3x36	3x37	hcar_off	5.86	0	0	0	1	2
3x36	6x48	hcar_off	8.53	0	0	0	1	2
3x36	6x51	hcar_off	4.69	0	0	0	1	2
3x36	7x42	hcar_off	9.135	0	0	0	1	1
3x37	6x55	hcar_off	5.655	0	1	0	2	2
4x61	E2	hcar_off	7.18	0	1	0	2	1
4x64	4x68	hcar_off	5.19	0	1	0	2	2
4x64	E2	hcar_off	6.39	0	1	0	2	1
4x68	E2	hcar_off	5.82	0	1	0	2	1
4x68	E2x51	hcar_off	4.76	0	1	0	2	1
E2	E2	Shared	20.305	31.3295	1	1	1	1
E2	E2x51	Shared	9.7	3.6225	1	1	1	1
E2x50	Lig	hcar_off	4.72	0	1	1	1	0
E2	E2x52	hcar_off	11.51	0	1	1	1	1
7x34	E2x52	hcar_off	8.05	0	1	1	2	1
5x39	E2	hcar_off	9.435	0	1	0	2	1
6x55	E2	hcar_off	11.155	0	1	0	2	1
6x59	E2	hcar_off	5.67	0	1	0	2	1
6x58	E2	hcar_off	12.58	0	1	0	2	1
7x34	E2	Shared	5.27	9.1645	1	1	2	1
5x40	6x55	hcar_off	11.86	0	0	1	2	2
6x51	6x55	hcar_off	9.26	0	1	0	2	2
6x55	7x34	Shared	5.14	10.368	1	0	2	2
6x58	7x34	hcar_off	8.23	0	1	0	2	2
7x34	7x38	Shared	13.89	3.7775	1	1	2	1
7x35	7x38	hcar_off	5.635	0	0	0	1	1
7x38	Lig	Shared	13.855	8.288	1	0	1	0
7x42	Lig	Shared	4.535	5.6155	1	1	1	0
3x29	4x65	hcar_off	4.385	0	1	1	1	2
3x37	5x461	Shared	4.35	3.631	1	0	2	2
1x30	7x35	hcar_off	4.28	0	0	0	2	1
6x51	7x41	hcar_off	4	0	1	0	2	2
1x36	2x61	hcar_off	3.1	0	0	0	2	2
3x26	E2	hcar_off	2.94	0	1	0	2	1
1x39	2x61	Shared	2.42	4.7355	0	0	1	2
3x21	E2	hcar_off	2.11	0	0	0	2	1
2x67	Lig	hcar_off	0.42	0	0	0	1	0
NT	NT	hcar_on	0	21.496	0	1	2	2
E2	NT	hcar_on	0	16.2495	1	1	1	2
1x27	2x67	hcar_on	0	5.1175	0	1	2	1
1x27	E2	hcar_on	0	3.6145	0	1	2	1
1x31	1x35	hcar_on	0	4.4945	1	0	1	2
1x31	7x32	hcar_on	0	7.9225	1	0	1	2
2x57	7x42	hcar_on	0	4.221	0	0	2	1
2x60	2x64	hcar_on	0	5.353	0	0	1	1
2x63	E1	hcar_on	0	7.0355	0	0	2	2
7x35	E1	hcar_on	0	4.2085	0	0	1	2
E1x49	E2	hcar_on	0	6.4375	0	0	2	1
3x25	E1x50	hcar_on	0	6.7895	0	1	2	1
3x22	3x26	hcar_on	0	4.0485	1	1	2	2
3x25	E2	hcar_on	0	7.769	0	1	2	1
3x36	5x461	hcar_on	0	4.4195	0	0	1	2
3x36	7x41	hcar_on	0	5.1075	0	0	1	2
3x36	Lig	hcar_on	0	10.001	0	0	1	0
4x63	E2	hcar_on	0	4.1885	0	0	2	1
E2x51	Lig	hcar_on	0	4.3735	1	1	1	0
5x40	E2x52	hcar_on	0	4.4635	0	1	2	1
E2x52	Lig	hcar_on	0	4.8195	1	1	1	0
5x40	E2	hcar_on	0	6.167	0	1	2	1
5x44	E2	hcar_on	0	6.163	0	1	2	1
E2	Lig	hcar_on	0	11.268	1	1	1	0
5x44	5x461	hcar_on	0	5.3075	0	1	2	2
5x44	6x51	hcar_on	0	4.885	0	1	2	2
1x36	2x64	hcar_on	0	3.475	0	0	2	1
2x64	7x35	hcar_on	0	5.156	1	0	1	1
E1x50	E2	hcar_on	0	4.6085	1	1	1	1
7x35	Lig	hcar_on	0	4.33	0	0	1	0
E1	NT	hcar_on	0	3.955	0	1	2	2
1x25	E2	hcar_on	0	3.1915	0	0	2	1
2x53	3x32	hcar_on	0	2.862	1	0	2	1
3x26	4x64	hcar_on	0	2.787	1	0	2	2
1x42	7x42	hcar_on	0	2.7495	0	0	2	1
2x56	3x32	hcar_on	0	2.604	0	0	2	1
1x30	7x32	hcar_on	0	2.1315	0	0	2	2
1x29	2x67	hcar_on	0	1.846	0	0	2	1
1x32	2x67	hcar_on	0	1.7655	0	0	2	1
5x32	E2x51	hcar_on	0	1.141	0	0	2	1

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Difference Members
	Id	Description
	hcar_off	succinate_off
	hcar_on	hca_on

Network Difference
Value	hcar_off	hcar_on
I_min	4.46	3.427
Number of Linked Nodes	265	271
Number of Specific Nodes	12 (4.53%)	18 (6.64%)
Number of Shared Nodes	253 (95.47%)	253 (93.36%)
Number of Links	308	301
Number of Specific Links	201 (65.26%)	194 (64.45%)
Number of Shared Links	107 (34.74%)	107 (35.55%)
Number of Hubs	39	32
Number of Specific Hubs	27 (69.23%)	20 (62.50%)
Number of Shared Hubs	12 (30.77%)	12 (37.50%)
Average % Shared Neighbours (Jaccard)	22.74
Average % Shared Neighbours (Otsuka)	30.63
Average % Shared Neighbours (Overlap Coefficient)	38.63
Average % Shared Cliques (k3-6)	76.83
Graphlets Similarity	0.582669

Paths Difference
Value	hcar_off	hcar_on
Number Of Nodes in MetaPath	63	54
Specific Nodes in MetaPath	44 (69.84%)	35 (64.81%)
Shared Nodes in MetaPath	253 (95.47%)	253 (95.47%)
Number Of Links MetaPath	66	54
Specific Links in MetaPath	59 (89.39%)	47 (87.04%)
Shared Links in MetaPath	107 (34.74%)	107 (34.74%)
Number of Shortest Paths	52483	42955
Length Of Smallest Path	3	3
Average Path Length	14.1198	13.8796
Length of Longest Path	36	32
Minimum Path Strength	1.27	0.1285
Average Path Strength	8.21559	5.76926
Maximum Path Strength	22.4125	14.071
Minimum Path Correlation	0.7	0.701
Average Path Correlation	0.910277	0.914192
Maximum Path Correlation	0.99	0.99
Minimum % Of Corr. Nodes	3.84615	3.7037
Average % Of Corr. Nodes	42.3905	41.8539
Maximum % Of Corr. Nodes	100	100
Minimum Path Hubs %	0	0
Average Path Hubs %	46.9527	35.6947
Maximum Path Hubs %	100	100

Details about the values in these tables can be found in the corresponding documentation page .

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