Orange: nodes, hubs and links specific of kop_on_gp network

Green: nodes, hubs and links shared by both networks

Purple: nodes, hubs and links specific of kop_off network

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Owner: the name of the network the hub belong to or "Shared" if the corresponding hub is present in both networks.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub in the corresponding network.

Num Of Links: the number of links of the corresponding hub in the corresponding network.

ConSurf: this column reports the ConSurf conservation grades of each hub.


Index Hub Owner kop_on_gp Avg Int. Strength kop_off Avg Int. Strength kop_on_gp Num Of Links kop_off Num Of Links ConSurf
11x39 kop_on_gp4.089335.38667536
21x60 kop_on_gp3.21254.075425
32x46 kop_on_gp5.0545.805529
42x50 kop_on_gp6.558676.98333539
52x59 kop_on_gp4.3408310.93425
62x64 kop_on_gp6.33256.63424
73x37 kop_on_gp5.171337.26333536
83x45 kop_on_gp3.753334.435426
9I2x57 kop_on_gp7.579179.145426
10E2.R202 kop_on_gp4.486677.51432
11E2.V207 kop_on_gp2.754.15333533
125x44 kop_on_gp6.637.73667435
135x65 kop_on_gp4.000834.47418
146x30 kop_on_gp2.825333.93526
156x32 kop_on_gp4.5910.81427
166x49 kop_on_gp3.70754.005425
176x51 kop_on_gp3.073334.51333436
186x52 kop_on_gp5.716678.44438
197x34 kop_on_gp8.09259.15667434
207x35 kop_on_gp6.246118.69333634
217x47 kop_on_gp2.7354.83667437
22G.HN.43 kop_on_gp3.78750409
23G.S1.02 kop_on_gp5.001330505
24G.S1.05 kop_on_gp5.263330409
25G.S1.06 kop_on_gp4.410508
26G.S2.08 kop_on_gp9.055830405
27G.S3.01 kop_on_gp3.777330504
28G.S3.03 kop_on_gp6.760670507
29G.S3.04 kop_on_gp7.154170406
30G.S3.06 kop_on_gp6.6650405
31G.S3.07 kop_on_gp4.970830409
32G.s3h2.03 kop_on_gp4.515830409
33G.H2.04 kop_on_gp4.394170409
34G.H2.06 kop_on_gp5.089520709
35G.H2.07 kop_on_gp4.492380709
36G.H2.09 kop_on_gp4.77250408
37G.h2s4.01 kop_on_gp6.334670509
38G.S4.02 kop_on_gp4.938670508
39G.S4.03 kop_on_gp3.725830407
40G.S4.05 kop_on_gp2.739170407
41G.S4.07 kop_on_gp4.38250408
42G.s4h3.04 kop_on_gp7.1540508
43G.s4h3.05 kop_on_gp5.275330509
44G.s4h3.06 kop_on_gp3.779170408
45G.H3.01 kop_on_gp6.170609
46G.H3.09 kop_on_gp5.831430709
47G.H3.13 kop_on_gp5.019170405
48G.H3.15 kop_on_gp4.428330408
49G.H3.17 kop_on_gp6.857780605
50G.H3.18 kop_on_gp6.92750409
51G.S5.02 kop_on_gp4.8350406
52G.S5.03 kop_on_gp2.985330508
53G.S5.04 kop_on_gp4.8550409
54G.S5.05 kop_on_gp3.774290709
55G.S5.07 kop_on_gp4.131670409
56G.s5hg.01 kop_on_gp5.66750409
57G.HG.04 kop_on_gp4.811670409
58G.hgh4.02 kop_on_gp4.908330407
59G.hgh4.05 kop_on_gp6.432670507
60G.H4.03 kop_on_gp6.300830404
61G.H4.10 kop_on_gp6.620506
62G.H4.11 kop_on_gp3.080830407
63G.H4.15 kop_on_gp4.521110608
64G.h4s6.02 kop_on_gp7.49750408
65G.S6.02 kop_on_gp6.115560607
66G.s6h5.02 kop_on_gp2.97250407
67G.H5.03 kop_on_gp3.5980508
68G.H5.05 kop_on_gp6.210405
69G.H5.08 kop_on_gp6.388670508
70G.H5.25 kop_on_gp3.091670407
71b.1x15 kop_on_gp3.5650407
72b.lh12x2 kop_on_gp5.77250408
73b.h2x5 kop_on_gp3.488330405
74b.lhb1x3 kop_on_gp4.618330402
75b.lhb1x6 kop_on_gp3.689170403
76b.lhb1x9 kop_on_gp2.964170403
77b.lhb1x11 kop_on_gp3.680404
78b.b1x4 kop_on_gp3.565830407
79b.l1x3 kop_on_gp7.979440609
80b.b2x1 kop_on_gp7.367330508
81b.b2x5 kop_on_gp6.717220607
82b.l3x2 kop_on_gp5.379330509
83b.b4x6 kop_on_gp9.534760709
84b.b5x2 kop_on_gp5.67750407
85b.b5x3 kop_on_gp6.587620709
86b.b5x5 kop_on_gp5.089170405
87b.b5x7 kop_on_gp4.82750407
88b.l5x1 kop_on_gp4.930408
89b.l5x5 kop_on_gp6.399580809
90b.b6x5 kop_on_gp3.771670406
91b.l6x5 kop_on_gp6.528330404
92b.b7x1 kop_on_gp5.632670504
93b.b7x2 kop_on_gp3.5250408
94b.l7x2 kop_on_gp3.9060509
95b.l7x4 kop_on_gp3.154170409
96b.b8x4 kop_on_gp4.931110606
97b.l9x3 kop_on_gp7.077220609
98b.l9x6 kop_on_gp4.994440908
99b.l9x7 kop_on_gp3.201670407
100b.b10x5 kop_on_gp4.200670509
101b.b11x4 kop_on_gp5.95250409
102b.l11x2 kop_on_gp7.2040509
103b.b12x6 kop_on_gp8.818570708
104b.l12x1 kop_on_gp3.138330406
105b.b13x7 kop_on_gp8.730507
106b.l13x3 kop_on_gp8.930560609
107b.l13x6 kop_on_gp4.3160509
108b.l13x7 kop_on_gp4.063330509
109b.b14x3 kop_on_gp4.84750405
110b.b14x5 kop_on_gp4.44750405
111b.b15x1 kop_on_gp6.458890609
112b.b15x3 kop_on_gp4.38750409
113b.l15x2 kop_on_gp5.703330509
114b.b16x4 kop_on_gp12.12330406
115b.b16x5 kop_on_gp5.715830405
116b.b16x6 kop_on_gp8.520608
117b.b16x7 kop_on_gp6.931670409
118b.b17x5 kop_on_gp7.0620507
119b.b17x7 kop_on_gp8.39750408
120b.l17x3 kop_on_gp7.657920809
121b.l17x6 kop_on_gp5.524670509
122b.b18x3 kop_on_gp5.35250408
123b.l18x1 kop_on_gp5.485420806
124b.l18x2 kop_on_gp5.475830407
125b.b19x2 kop_on_gp6.224290706
126b.b19x4 kop_on_gp5.323330508
127b.l19x1 kop_on_gp6.420830409
128b.l19x2 kop_on_gp6.181670409
129b.b20x2 kop_on_gp4.857330506
130b.b20x4 kop_on_gp8.560608
131b.b20x6 kop_on_gp6.773330606
132b.b21x1 kop_on_gp10.51250407
133b.b21x3 kop_on_gp6.120406
134b.b21x5 kop_on_gp6.150830404
135b.b21x7 kop_on_gp5.654440605
136b.l21x5 kop_on_gp3.217330504
137b.b22x5 kop_on_gp4.532860707
138b.l22x5 kop_on_gp7.670830409
139b.b23x6 kop_on_gp6.530707
140b.l23x1 kop_on_gp8.3150406
141b.b24x3 kop_on_gp3.389170405
142b.b24x4 kop_on_gp6.679330506
143b.b24x6 kop_on_gp6.54250408
144b.l24x3 kop_on_gp4.680405
145b.b25x3 kop_on_gp7.464170405
146b.l25x3 kop_on_gp9.226670509
147b.l25x6 kop_on_gp12.56920408
148b.l26x5 kop_on_gp5.048330405
149b.l27x1 kop_on_gp10.33240709
150b.l27x2 kop_on_gp7.206670409
151b.b28x3 kop_on_gp4.4320507
152b.b28x4 kop_on_gp6.29250406
153b.b28x6 kop_on_gp7.395330509
154g.h1x5 kop_on_gp2.470830406
155g.h1x14 kop_on_gp4.525830409
156g.l1x4 kop_on_gp5.542670508
157g.h2x11 kop_on_gp8.0350406
158g.ctx3 kop_on_gp5.620560609
159g.ctx14 kop_on_gp4.986670509
160g.ctx15 kop_on_gp7.30409
161g.ctx16 kop_on_gp4.687080808
1621x43 Shared5.004174.2125447
1632x42 Shared5.083336.522657
1642x57 Shared6.606677.902457
165E1x50 Shared8.159.60167568
166E1x52 Shared5.6561111.062657
1673x34 Shared4.554177.2475445
1683x51 Shared7.49256.876457
1694x50 Shared7.72259.795449
170E2.F214 Shared4.264176.828456
1715x47 Shared5.534177.4275448
1725x58 Shared5.986678.7825548
1736x48 Shared4.985247.42375788
1747x38 Shared4.913336.96545
1757x42 Shared7.3110.5725546
1767x49 Shared5.945336.8425549
1777x53 Shared5.271117.1775649
1788x50 Shared5.641677.30667468
179Lig Shared6.843149.2023117130
1801x54 kop_off4.563333.09147
1812x41 kop_off2.885563.034355
1822x45 kop_off7.194449.602359
1832x56 kop_off4.715564.215347
1843x38 kop_off6.666677.08347
1853x41 kop_off3.551114.205346
1863x50 kop_off5.912226.68167369
1874x56 kop_off5.8854.3675245
1885x35 kop_off5.831678.56247
1895x40 kop_off5.303337.38344
1906x44 kop_off4.929.378259
1917x45 kop_off6.776677.86349
1928x48 kop_off5.526675.865344
   
Orange: nodes, hubs and links specific of kop_on_gp network

Green: nodes, hubs and links shared by both networks

Purple: nodes, hubs and links specific of kop_off network

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Owner: the name of the network the link belong to or "Shared" if the corresponding link is present in both networks.

Recurrence: the relative Recurrence in the filtered pool of shortest paths.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.


Index Node1 Node2 Owner kop_on_gp Recurrence kop_off Recurrence kop_on_gp Hub1? kop_off Hub1? kop_on_gp Hub2? kop_off Hub2? ConSurf1 ConSurf2
13x50 7x53 kop_on_gp66.34730NoYesYesYes99
23x50 G.H5.23 kop_on_gp33.41730NoYesNoNo94
3G.H5.23 I2x57 kop_on_gp18.39340NoNoYesNo46
42x59 3x28 kop_on_gp10.41520YesNoNoNo56
53x50 5x58 kop_on_gp33.27850NoYesYesYes98
63x54 5x61 kop_on_gp34.66210NoNoNoNo88
73x54 5x65 kop_on_gp34.81352.11422NoNoYesNo88
8G.H5.23 G.H5.25 kop_on_gp51.56660NoNoYesNo47
9G.H5.20 G.H5.25 kop_on_gp51.86660NoNoYesNo97
105x65 G.H5.20 kop_on_gp52.01940YesNoNoNo89
115x65 I3.L259 kop_on_gp86.86850YesNoNoNo83
125x68 I3.L259 kop_on_gp88.14980NoNoNoNo63
135x68 G.H5.13 kop_on_gp88.29580NoNoNoNo68
14G.H5.13 G.S6.02 kop_on_gp88.44180NoNoYesNo87
15G.S5.03 G.S6.02 kop_on_gp89.72690YesNoYesNo87
16G.S5.03 G.S5.05 kop_on_gp89.25970YesNoYesNo89
17G.S4.05 G.S5.05 kop_on_gp49.41260YesNoYesNo79
18G.S4.05 G.S5.07 kop_on_gp49.63750YesNoYesNo79
19G.S5.07 G.s5hg.01 kop_on_gp99.95290YesNoYesNo99
20G.S4.07 G.s5hg.01 kop_on_gp1000YesNoYesNo89
21G.S4.07 G.s4h3.03 kop_on_gp49.99590YesNoNoNo88
22G.s4h3.03 G.s4h3.06 kop_on_gp49.99810NoNoYesNo88
23G.s4h3.05 G.s4h3.06 kop_on_gp50.27740YesNoYesNo98
24G.s4h3.04 G.s4h3.05 kop_on_gp49.87940YesNoYesNo89
25G.HG.04 G.s4h3.04 kop_on_gp99.53580YesNoYesNo98
26G.HG.04 G.s4h3.01 kop_on_gp98.63940YesNoNoNo97
27G.S5.06 G.s4h3.01 kop_on_gp94.34930NoNoNoNo87
28G.S5.04 G.S5.06 kop_on_gp93.64910YesNoNoNo98
29G.H3.09 G.S5.04 kop_on_gp91.7690YesNoYesNo99
30G.H3.09 G.S5.02 kop_on_gp76.92380YesNoYesNo96
31G.S4.02 G.S5.02 kop_on_gp76.75930YesNoYesNo86
32G.H3.18 G.S4.02 kop_on_gp35.18930YesNoYesNo98
33G.H3.15 G.H3.18 kop_on_gp34.87110YesNoYesNo89
34G.H3.15 G.H3.17 kop_on_gp35.16080YesNoYesNo85
35G.H3.17 b.l27x1 kop_on_gp12.86410YesNoYesNo59
36b.b26x1 b.l27x1 kop_on_gp12.42240NoNoYesNo99
37b.b26x1 b.b26x2 kop_on_gp12.27120NoNoNoNo97
38b.b26x2 b.b2x3 kop_on_gp12.1280NoNoNoNo76
39G.S5.05 G.s6h5.01 kop_on_gp49.3380YesNoNoNo99
40G.S5.07 G.s6h5.01 kop_on_gp50.19410YesNoNoNo99
41G.H3.01 G.S4.07 kop_on_gp50.20480YesNoYesNo98
42G.H3.01 G.s4h3.06 kop_on_gp50.22980YesNoYesNo98
43G.HG.07 G.s4h3.06 kop_on_gp49.9150NoNoYesNo98
44G.HG.07 G.s4h3.04 kop_on_gp49.85980NoNoYesNo98
45G.S1.05 G.S4.02 kop_on_gp41.19640YesNoYesNo98
46G.S1.05 G.h2s4.01 kop_on_gp40.92320YesNoYesNo99
47G.h2s4.01 b.l5x5 kop_on_gp38.61770YesNoYesNo99
48b.l5x3 b.l5x5 kop_on_gp38.37890NoNoYesNo89
49b.l5x3 b.l7x3 kop_on_gp38.22320NoNoNoNo89
50b.l7x3 b.l7x5 kop_on_gp38.06890NoNoNoNo96
51b.b9x3 b.l7x5 kop_on_gp37.76250NoNoNoNo66
52b.b9x3 b.l8x10 kop_on_gp37.45110NoNoNoNo64
53b.b8x4 b.l8x10 kop_on_gp37.31460YesNoNoNo64
54G.H3.09 G.S4.04 kop_on_gp13.82250YesNoNoNo99
55G.H3.08 G.S4.04 kop_on_gp13.79290NoNoNoNo99
56G.H2.04 G.H3.08 kop_on_gp13.51120YesNoNoNo99
57G.H2.04 G.H2.07 kop_on_gp13.29440YesNoYesNo99
58G.H2.07 b.l9x6 kop_on_gp10.72920YesNoYesNo98
59G.H3.17 b.l25x6 kop_on_gp21.26710YesNoYesNo58
60b.b7x2 b.b8x4 kop_on_gp34.99550YesNoYesNo86
61b.b6x5 b.b7x2 kop_on_gp36.57370YesNoYesNo68
62b.b2x4 b.b6x5 kop_on_gp36.07340NoNoYesNo66
63b.b10x4 b.b2x4 kop_on_gp35.90640NoNoNoNo66
64b.b10x4 b.b14x5 kop_on_gp34.35540NoNoYesNo65
65b.b14x5 b.b15x1 kop_on_gp32.9990YesNoYesNo59
66b.b15x1 b.b16x6 kop_on_gp31.82530YesNoYesNo98
67b.b16x4 b.b16x6 kop_on_gp13.89950YesNoYesNo68
68b.b16x4 b.b17x6 kop_on_gp13.75850YesNoNoNo67
69b.b17x6 g.h1x14 kop_on_gp13.5870NoNoYesNo79
70b.1x15 g.h1x14 kop_on_gp24.40680YesNoYesNo79
71b.b16x6 b.b17x3 kop_on_gp16.42810YesNoNoNo85
72b.b17x3 g.h1x10 kop_on_gp16.26190NoNoNoNo59
73g.h1x10 g.h1x14 kop_on_gp13.59160NoNoYesNo99
74b.1x15 b.1x19 kop_on_gp19.8960YesNoNoNo76
75b.1x19 b.b21x1 kop_on_gp18.15230NoNoYesNo67
76b.l23x1 b.l25x6 kop_on_gp13.06170YesNoYesNo68
77b.l21x7 b.l23x1 kop_on_gp12.78170NoNoYesNo56
78b.b23x6 b.l21x7 kop_on_gp12.11570YesNoNoNo75
79b.b17x7 b.b21x1 kop_on_gp11.87280YesNoYesNo87
806x48 Lig Shared41.510179.6917YesYesYesYes80
816x48 7x45 Shared57.145336.0091YesYesNoYes89
827x45 7x49 Shared58.113440.3344NoYesYesYes99
837x49 7x53 Shared61.003833.8149YesYesYesYes99
843x28 Lig Shared11.028434.017NoNoYesYes60
855x58 5x61 Shared34.504826.8784YesYesNoNo88
865x40 6x55 Shared10.567338.6877NoYesNoNo45
871x42 2x57 kop_off3.5459924.482NoNoYesYes77
881x38 1x42 kop_off011.8219NoNoNoNo57
891x34 1x38 kop_off010.3731NoNoNoNo55
901x42 7x47 kop_off2.2079711.8219NoNoYesNo77
912x50 7x49 kop_off2.6715112.9001YesNoYesYes99
927x42 Lig kop_off6.1156433.0231YesYesYesYes60
932x57 7x42 kop_off5.5027433.7727YesYesYesYes76
941x52 8x54 kop_off014.9469NoNoNoNo66
958x50 8x54 kop_off017.8361YesYesNoNo86
962x43 8x50 kop_off034.7161NoNoYesYes88
972x43 7x53 kop_off035.0699NoNoYesYes89
981x52 8x57 kop_off013.4897NoNoNoNo60
992x48 4x50 kop_off0.53705210.9628NoNoYesYes69
1002x45 4x50 kop_off3.5763826.6552NoYesYesYes99
1012x45 4x49 kop_off097.6078NoYesNoNo97
1023x41 4x49 kop_off1.36584100NoYesNoNo67
1033x37 3x41 kop_off1.0534841.6189YesNoNoYes66
1043x37 4x56 kop_off1.0029541.2315YesNoNoYes65
1053x33 4x56 kop_off042.7729NoNoNoYes55
1063x33 Lig kop_off0.67304943.2488NoNoYesYes50
1073x40 3x41 kop_off062.8327NoNoNoYes76
1083x40 6x44 kop_off066.5179NoNoNoYes79
1096x44 6x48 kop_off0.66767861.1734NoYesYesYes98
1101x57 8x50 kop_off022.6541NoNoYesYes78
1112x42 4x46 kop_off5.5333567.9372YesYesNoNo77
1122x45 4x46 kop_off4.8225577.9523NoYesNoNo97
1133x50 6x37 kop_off022.5615NoYesNoNo98
1143x46 6x37 kop_off063.2202NoNoNoNo88
1152x42 3x46 kop_off0.23058765.0691YesYesNoNo78
1162x41 4x46 kop_off0.53793827.2785NoYesNoNo57
1172x41 4x42 kop_off010.8406NoYesNoNo57
1182x42 4x42 kop_off0.17935210.7564YesYesNoNo77
1197x38 Lig kop_off5.6692316.7242YesYesYesYes50
1207x34 7x38 kop_off0.011687223.2311YesNoYesYes45
1212x66 E1x51 kop_off046.5423NoNoNoNo41
122E1x51 E1x52 kop_off0.33810449.0482NoNoYesYes17
123E1x49 E2.V207 kop_off1.0141921.02NoNoYesNo43
1242x66 E1x49 kop_off044.028NoNoNoNo44
1253x28 E1x50 kop_off032.9009NoNoYesYes68
126E1x50 E2x50 kop_off0.33745432.9894YesYesNoNo89
127E2x50 Lig kop_off035.4195NoNoYesYes90
1283x22 E2.T199 kop_off6.7119913.1991NoNoNoNo24
129E2.I208 E2.T199 kop_off015.8145NoNoNoNo44
130E1x49 E2.I208 kop_off0.67617821.02NoNoNoNo44
1313x34 4x50 kop_off2.3264414.551YesYesYesYes59
1326x48 6x52 kop_off4.930116.421YesYesYesNo88
1333x47 5x58 kop_off0.34397710.5037NoNoYesYes98
1345x58 6x37 kop_off0.17200340.625YesYesNoNo88
1353x51 5x61 kop_off024.861YesYesNoNo78
1363x51 5x64 kop_off010.5037YesYesNoNo75
1372x41 4x39 kop_off011.8977NoYesNoNo52
1385x32 E2.F214 kop_off021.8918NoNoYesYes16
1395x32 5x36 kop_off026.0487NoNoNoNo14
1405x36 5x40 kop_off9.239828.1755NoNoNoYes44
1416x55 Lig kop_off5.6940828.1418NoNoYesYes50
142E2.R202 E2.V205 kop_off013.1991YesNoNoNo21
143E2.V205 E2.V207 kop_off015.8145NoNoYesNo13
1445x35 E2.F214 kop_off4.6509913.237NoYesYesYes76
1455x47 6x52 kop_off2.3448321.8287YesYesYesNo88
1466x27 6x30 kop_off010.3689NoNoYesNo36
1473x50 6x30 kop_off012.2978NoYesYesNo96
1488x48 8x49 kop_off010.3479NoYesNoNo46
1498x47 8x49 kop_off0.34976111.8219NoNoNoNo86
1508x47 8x50 kop_off0.69943417.6255NoNoYesYes88
1516x48 6x51 kop_off6.5469219.9587YesYesYesNo86
1526x51 6x55 kop_off5.5611213.3465YesNoNoNo65
1536x54 7x34 kop_off2.6706811.6745NoNoYesNo54
1541x57 I1x51 kop_off022.1782NoNoNoNo77
155E1x50 E1x52 kop_off0.0035120858.5622YesYesYesYes87
1562x41 I1x51 kop_off021.3191NoYesNoNo57

Here, those paths that begin and end at given residue pair(s) or that pass through a residue are used to generate a novel metapath. Such a path filtering is particularly recommended if some information on allosteric residues is available. The selection syntax for a residue pair ("Pairs") is C:C:c534,A:A:?600 (the lower-case "c" stands for cytosine and "?" indicates any non standard amino acid or nucleotide residue). Selection of more than one apical residue pair has the following syntax: C:C:c534,A:A:?600,C:C:c534,A:A:E41. Only one residue can be selected as a tail ("Tail"). For midway residue(s), each residue must be separated by a comma as well e.g. A:A:?600,A:A:E41.

Midway



Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.


2D representation of the interactions of this orthosteric/allosteric ligand.


Node1Node2OwnerNet1LinkStrengthNet2LinkStrengthComm1Comm2Node1ShellNode2Shell
1x392x57Shared5.993.193330322
2x563x31kop_off4.5601312
2x567x42Shared4.993.746671311
2x56Ligkop_off5.7401310
2x577x42Shared17.9611.57331021
2x607x38Shared5.494.571311
2x607x42Shared5.6411.27331311
2x60LigShared9.514.54331310
3x25E1x50Shared5.226.093331322
3x28E1x50kop_off7.3600312
E1x50E2x50Shared23.5112.62331321
3x25E2x50Shared7.287.281321
3x28LigShared3.874.680310
3x32LigShared33.4717.14330310
3x334x56kop_off5.0500312
3x33LigShared6.098.370310
3x356x48kop_off4.5200021
3x366x48Shared6.985.043331311
3x366x52kop_off5.2501311
3x36LigShared11.018.093331310
3x374x56Shared9.189.616670022
3x406x44kop_off7.5400022
E2x50Ligkop_off4.1201310
5x32E2x51kop_off3.8200012
5x32E2.F214kop_off12.3800012
5x39E2.F214kop_off6.2200022
5x325x36kop_off12.6400012
5x365x40Shared16.596.450022
5x406x55Shared7.276.783330021
5x406x58kop_off4.0500021
5x43LigShared8.74.283330310
5x476x52Shared15.846.033330321
6x446x48Shared22.056.346671021
6x447x45kop_off7.2501022
6x486x51Shared4.73.916671312
6x486x52Shared4.234.936671311
6x487x41kop_off4.2201312
6x487x45Shared6.789.041312
6x48LigShared5.912.873331310
6x516x55Shared4.423.926670021
6x517x38kop_off4.4200021
6x547x34Shared7.228.596670021
6x55LigShared10.196.103330310
7x347x35Shared6.954.633330312
7x347x38Shared13.37.653330311
7x38LigShared4.634.683331310
7x42LigShared13.76.506671310
E2.F214E2x52kop_off3.6500022
3x29LigShared2.77.176670310
5x445x47Shared2.147.860322
2x552x56kop_off1.5700021
1x397x35kop_on_gp06.950322
1x397x38kop_on_gp02.823330321
2x563x28kop_on_gp03.173331311
2x563x32kop_on_gp07.226671311
2x59E1x50kop_on_gp03.006670322
2x593x28kop_on_gp08.30321
3x293x33kop_on_gp03.150311
3x29E2x52kop_on_gp02.783330312
3x313x35kop_on_gp03.303330022
3x327x42kop_on_gp03.450311
3x33E2x52kop_on_gp03.910312
3x363x37kop_on_gp03.733331312
3x375x43kop_on_gp05.240021
3x406x48kop_on_gp02.740021
5x36E2.F214kop_on_gp09.153330022
5x32Ligkop_on_gp08.230010
5x446x52kop_on_gp08.673330321
6x546x58kop_on_gp06.220021
6x58Ligkop_on_gp03.490310
7x34Ligkop_on_gp011.48670310
7x357x38kop_on_gp04.836670321
6x52Ligkop_on_gp03.223331310
5x395x43kop_on_gp02.026670021
6x517x41kop_on_gp01.176670022

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Difference Members
Id Description
kop_on_gp 8F7W-κ-Dynorphin-Gi1/β1/γ2
8DZS-κ-GR89,696-chim(NtGi2-Gz)/β1/γ2
8DZP-κ-momSalB-Gi1/β1/γ2
kop_off 4DJH-κ-JDTic
Network Difference
Value kop_on_gp kop_off
Imin 2.58333 3.77
Number of Linked Nodes 882 267
Number of Specific Nodes 626 (70.98%) 11  (4.12%)
Number of Shared Nodes 256 (29.02%) 256  (95.88%)
Number of Links 1105 283
Number of Specific Links 967 (87.51%) 145  (51.24%)
Number of Shared Links 138 (12.49%) 138  (48.76%)
Number of Hubs 179 31
Number of Specific Hubs 161 (89.94%) 13  (41.94%)
Number of Shared Hubs 18 (10.06%) 18  (58.06%)
Average % Shared Neighbours (Jaccard) 10.09
Average % Shared Neighbours (Otsuka) 12.75
Average % Shared Neighbours (Overlap Coefficient) 15.28
Average % Shared Cliques (k3-6) 50.61
Graphlets Similarity 0.619884
Paths Difference
Value kop_on_gp kop_off
Number Of Nodes in MetaPath 83 73
Specific Nodes in MetaPath 72 (86.75%) 62  (84.93%)
Shared Nodes in MetaPath 256 (29.02%) 256  (29.02%)
Number Of Links MetaPath 86 77
Specific Links in MetaPath 79 (91.86%) 70  (90.91%)
Shared Links in MetaPath 138 (12.49%) 138  (12.49%)
Number of Shortest Paths 3844399 56638
Length Of Smallest Path 3 3
Average Path Length 41.8731 13.5668
Length of Longest Path 75 28
Minimum Path Strength 0.561111 1.19
Average Path Strength 5.36353 7.49257
Maximum Path Strength 21.6256 23.585
Minimum Path Correlation 0.7 0.7
Average Path Correlation 0.987962 0.927016
Maximum Path Correlation 1 0.99
Minimum % Of Corr. Nodes 1.63934 4.16667
Average % Of Corr. Nodes 30.7381 51.1576
Maximum % Of Corr. Nodes 100 100
Minimum Path Hubs % 0 0
Average Path Hubs % 59.0425 42.6738
Maximum Path Hubs % 100 100

Details about the values in these tables can be found in the corresponding documentation page .

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