psnGPCR

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Orange: nodes, hubs and links specific of lipid_off network

Green: nodes, hubs and links shared by both networks

Purple: nodes, hubs and links specific of lipid_on network

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Owner: the name of the network the link belong to or "Shared" if the corresponding link is present in both networks.

Strength: the interaction strength between the two nodes or 0 if the link is not present.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Owner	lipid_off Int. Strength	lipid_on Int. Strength	lipid_off Hub1?	lipid_on Hub1?	lipid_off Hub2?	lipid_on Hub2?	ConSurf1	ConSurf2
1	3x32	Lig	lipid_off	100	0	No	No	Yes	Yes	5	0
2	6x55	Lig	lipid_off	100	0	No	No	Yes	Yes	6	0
3	2x64	NT	lipid_off	100	0	Yes	No	Yes	Yes	3	5
4	3x25	NT	lipid_off	100	0	Yes	Yes	Yes	Yes	9	5
5	7x31	NT	lipid_off	100	0	No	No	Yes	Yes	2	5
6	1x39	7x42	lipid_off	100	0	No	No	No	No	6	6
7	2x39	3x50	lipid_off	100	0	No	No	Yes	No	8	9
8	2x41	4x43	lipid_off	100	0	No	Yes	No	No	4	1
9	3x33	5x43	lipid_off	100	0	Yes	No	No	No	4	5
10	3x40	5x50	lipid_off	100	0	No	No	No	No	8	7
11	3x43	6x44	lipid_off	100	0	No	No	No	No	8	9
12	3x46	6x37	lipid_off	100	0	No	No	No	No	9	8
13	3x48	3x52	lipid_off	100	0	No	No	No	No	6	5
14	3x49	3x50	lipid_off	100	0	Yes	Yes	Yes	No	9	9
15	3x49	I2x57	lipid_off	100	0	Yes	Yes	No	No	9	6
16	3x50	3x53	lipid_off	100	0	Yes	No	No	No	9	8
17	3x50	6x33	lipid_off	100	0	Yes	No	No	No	9	7
18	3x50	6x34	lipid_off	100	0	Yes	No	No	No	9	8
19	3x52	3x56	lipid_off	100	0	No	No	No	No	5	5
20	5x40	E2	lipid_off	100	0	No	No	Yes	Yes	5	5
21	5x40	6x59	lipid_off	100	0	No	No	No	Yes	5	3
22	6x51	7x41	lipid_off	100	0	No	No	No	No	6	7
23	Lig	NT	lipid_off	100	0	Yes	Yes	Yes	Yes	0	5
24	7x39	Lig	lipid_off	100	0	No	No	Yes	Yes	5	0
25	1x35	1x39	lipid_off	100	0	No	No	No	No	5	6
26	1x53	7x53	lipid_off	100	0	No	No	Yes	Yes	9	9
27	3x43	6x41	lipid_off	100	0	No	No	No	No	8	7
28	6x51	6x52	lipid_off	100	0	No	No	No	No	6	6
29	7x27	NT	lipid_off	100	0	No	No	Yes	Yes	2	5
30	1x27	7x31	lipid_off	100	0	No	No	No	No	0	2
31	1x27	7x35	lipid_off	100	0	No	No	No	No	0	4
32	1x31	1x32	lipid_off	100	0	No	No	No	No	5	5
33	1x35	2x64	lipid_off	100	0	No	No	Yes	No	5	3
34	2x63	2x64	lipid_off	100	0	No	No	Yes	No	3	3
35	2x63	E1x50	lipid_off	100	0	No	No	Yes	No	3	0
36	E1x50	E1x52	lipid_off	100	0	Yes	No	No	Yes	0	0
37	3x28	E1x50	lipid_off	100	0	No	No	Yes	No	5	0
38	3x36	3x37	lipid_off	100	0	No	No	Yes	No	6	6
39	E2x51	Lig	lipid_off	100	0	No	No	Yes	Yes	0	0
40	6x58	7x31	lipid_off	100	0	Yes	No	No	No	3	2
41	6x58	7x34	lipid_off	100	0	Yes	No	No	No	3	4
42	3x29	4x65	lipid_off	40	0	No	No	No	No	4	0
43	1x31	7x35	lipid_off	23.3333	0	No	No	No	No	5	4
44	3x33	4x61	lipid_off	40	0	Yes	No	No	No	4	6
45	I2x55	I2x57	lipid_off	20	0	No	No	No	No	4	6
46	3x44	5x54	lipid_off	60	0	No	No	No	No	6	8
47	6x54	7x33	lipid_off	30	0	No	No	No	No	4	3
48	I2x53	I2x57	lipid_off	40	0	No	No	No	No	7	6
49	1x40	2x61	lipid_off	60	0	No	No	No	No	5	6
50	2x49	4x50	lipid_off	50	0	No	No	No	No	8	9
51	6x29	6x32	lipid_off	40	0	No	No	No	No	5	8
52	4x59	E2	lipid_off	60	0	No	No	Yes	Yes	5	5
53	3x33	4x57	lipid_off	60	0	Yes	No	No	No	4	7
54	2x38	4x41	lipid_off	20	0	No	No	No	No	5	6
55	6x37	7x55	lipid_off	20	0	No	No	No	No	8	6
56	3x51	5x61	lipid_off	40	0	Yes	No	No	No	8	9
57	6x58	6x62	lipid_off	30	0	Yes	No	No	No	3	0
58	7x26	7x30	lipid_off	20	0	Yes	No	No	No	0	3
59	2x54	7x46	lipid_off	60	0	No	No	No	No	8	9
60	1x45	1x49	lipid_off	40	0	No	No	No	No	4	8
61	1x30	7x32	lipid_off	40	0	No	No	No	No	4	2
62	7x49	7x53	lipid_off	60	0	Yes	No	Yes	Yes	9	9
63	1x43	1x47	lipid_off	50	0	No	No	No	No	7	6
64	6x40	7x49	lipid_off	50	0	No	No	Yes	No	8	9
65	1x57	2x40	lipid_off	55	0	No	No	Yes	Yes	8	8
66	7x26	E3	lipid_off	30	0	Yes	No	Yes	Yes	0	1
67	5x46	5x50	lipid_off	40	0	No	No	No	No	5	7
68	1x28	NT	lipid_off	40	0	No	No	Yes	Yes	7	5
69	6x36	7x53	lipid_off	20	0	No	No	Yes	Yes	8	9
70	6x57	7x30	lipid_off	41.6667	0	No	No	No	No	4	3
71	2x39	2x40	lipid_off	40	0	No	No	Yes	Yes	8	8
72	7x28	NT	lipid_off	40	0	No	No	Yes	Yes	3	5
73	1x32	2x67	lipid_off	25	0	No	No	No	No	5	0
74	8x49	I1x49	lipid_off	30	0	No	No	No	No	6	6
75	5x44	5x48	lipid_off	26.6667	0	No	No	No	No	4	4
76	1x30	1x34	lipid_off	40	0	No	No	No	No	4	5
77	2x53	2x57	lipid_off	30	0	No	No	No	Yes	8	6
78	5x58	5x62	lipid_off	50	0	Yes	Yes	No	No	9	6
79	3x54	5x65	lipid_off	37.5	0	No	No	No	No	9	8
80	6x60	6x61	lipid_off	25	0	No	No	No	No	4	3
81	6x43	7x48	lipid_off	40	0	No	No	No	No	7	6
82	5x65	6x31	lipid_off	20	0	No	No	No	Yes	8	5
83	1x59	1x60	lipid_off	30	0	No	No	No	No	5	7
84	8x47	8x48	lipid_off	20	0	No	Yes	Yes	No	8	4
85	7x28	7x32	lipid_off	30	0	No	No	No	No	3	2
86	8x50	I1x50	lipid_off	20	0	No	No	No	No	8	8
87	1x60	8x53	lipid_off	40	0	No	No	No	No	7	7
88	5x63	5x64	lipid_off	40	0	No	No	No	Yes	3	6
89	2x66	E1x51	lipid_off	20	0	No	No	No	No	4	0
90	3x50	6x30	lipid_off	30	0	Yes	No	No	No	9	7
91	I2x50	I3	lipid_off	22.5	0	No	No	No	Yes	8	3
92	2x52	3x31	lipid_off	20	0	No	No	No	No	7	4
93	6x35	7x56	lipid_off	35	0	No	No	No	No	7	7
94	1x47	2x55	lipid_off	20	0	No	No	No	No	6	4
95	7x54	8x51	lipid_off	30	0	No	No	No	No	8	8
96	8x49	8x52	lipid_off	25	0	No	No	No	No	6	4
97	1x37	1x41	lipid_off	20	0	No	No	No	No	5	4
98	2x36	7x55	lipid_off	20	0	No	No	No	No	0	6
99	4x40	I2x56	lipid_off	23.3333	0	No	No	No	No	4	4
100	1x44	1x48	lipid_off	0	0	No	No	No	No	5	4
101	5x63	5x67	lipid_off	30	0	No	No	No	Yes	3	5
102	3x23	4x61	lipid_off	25	0	No	No	No	No	1	6
103	5x55	5x59	lipid_off	20	0	No	No	No	No	5	3
104	3x54	5x68	lipid_off	30	0	No	No	No	No	9	7
105	7x23	7x26	lipid_off	25	0	No	No	Yes	No	0	0
106	5x29	E3	lipid_off	20	0	No	No	Yes	Yes	0	1
107	7x29	7x33	lipid_off	17.5	0	No	No	No	No	3	3
108	4x54	4x58	lipid_off	10	0	No	No	No	No	3	4
109	4x43	4x47	lipid_off	20	0	No	No	No	No	1	4
110	3x41	4x52	lipid_off	15.8333	0	No	No	No	No	5	4
111	6x42	6x46	lipid_off	0	0	No	No	No	No	5	5
112	6x26	6x29	lipid_off	20	0	No	No	No	No	0	5
113	5x34	5x35	lipid_off	0	0	No	No	No	No	0	0
114	6x33	7x59	lipid_off	20	0	No	No	No	No	7	0
115	I2x54	I2x55	lipid_off	15.8333	0	No	No	No	No	5	4
116	6x25	6x28	lipid_off	20	0	No	No	No	No	0	4
117	6x28	8x48	lipid_off	20	0	No	No	Yes	No	4	4
118	8x59	8x63	lipid_off	20	0	No	No	No	No	5	2
119	6x461	6x47	lipid_off	1.66667	0	No	No	No	No	0	8
120	1x32	1x33	lipid_off	10	0	No	No	No	No	5	4
121	1x48	1x49	lipid_off	15	0	No	No	No	No	4	8
122	7x36	7x37	lipid_off	10	0	No	No	No	No	4	4
123	5x31	5x35	lipid_off	22.5	0	No	No	No	No	0	0
124	6x64	E2	lipid_off	0	0	No	No	Yes	Yes	0	5
125	4x55	4x56	lipid_off	0	0	No	No	No	No	3	5
126	7x62	CT	lipid_off	10	0	No	No	No	No	0	0
127	2x52	2x551	lipid_off	20	0	No	No	No	No	7	0
128	5x27	5x30	lipid_off	20	0	No	No	No	No	0	0
129	2x39	CT	lipid_off	10	0	No	No	No	No	8	0
130	1x58	2x44	lipid_off	6.66667	0	No	No	No	No	4	7
131	5x48	5x52	lipid_off	5	0	No	No	No	No	4	3
132	7x25	7x26	lipid_off	10	0	No	No	Yes	No	0	0
133	7x61	CT	lipid_off	10	0	No	No	No	No	0	0
134	1x26	7x28	lipid_off	10	0	No	No	No	No	0	3
135	1x55	8x61	lipid_off	10	0	No	No	No	No	5	3
136	7x45	Na1	lipid_off	10	0	Yes	No	No	No	9	0
137	6x27	6x31	lipid_off	0	0	No	No	No	Yes	0	5
138	1x25	1x28	lipid_off	5	0	No	No	No	No	0	7
139	8x58	8x59	lipid_off	0	0	No	No	No	No	6	5
140	5x69	I3	lipid_off	0	0	No	No	No	Yes	5	3
141	1x23	7x24	lipid_off	5	0	No	No	No	No	0	0
142	7x24	NT	lipid_off	0	0	No	No	Yes	Yes	0	5
143	5x28	NT	lipid_off	0	0	No	No	Yes	Yes	0	5
144	1x61	I1	lipid_off	0	0	No	No	No	No	0	7
145	6x24	6x27	lipid_off	0	0	No	No	No	No	0	0
146	4x51	4x55	lipid_off	0	0	No	No	No	No	3	3
147	5x66	5x70	lipid_off	5	0	No	No	No	No	5	5
148	1x24	1x26	lipid_off	2.5	0	No	No	No	No	0	0
149	5x27	5x29	lipid_off	0	0	No	No	No	No	0	0
150	8x54	8x58	lipid_off	0	0	No	No	No	No	6	6
151	6x64	6x65	lipid_off	0	0	No	No	No	No	0	0
152	1x20	1x24	lipid_off	0	0	No	No	No	No	0	0
153	2x60	Lig	Shared	100	100	No	No	Yes	Yes	4	0
154	2x64	Lig	Shared	100	100	Yes	No	Yes	Yes	3	0
155	3x29	Lig	Shared	100	100	No	No	Yes	Yes	4	0
156	3x33	Lig	Shared	100	100	Yes	No	Yes	Yes	4	0
157	E2	Lig	Shared	100	100	Yes	Yes	Yes	Yes	5	0
158	7x38	Lig	Shared	100	100	No	No	Yes	Yes	5	0
159	NT	NT	Shared	100	100	Yes	Yes	Yes	Yes	5	5
160	E2	NT	Shared	100	100	Yes	Yes	Yes	Yes	5	5
161	1x43	2x58	Shared	100	100	No	No	No	No	7	6
162	1x49	7x50	Shared	100	100	No	No	No	No	8	9
163	1x50	2x47	Shared	100	60.4762	Yes	Yes	No	No	9	9
164	1x50	2x50	Shared	100	100	Yes	Yes	Yes	Yes	9	9
165	1x50	7x50	Shared	100	100	Yes	Yes	No	No	9	9
166	1x57	2x44	Shared	100	100	No	No	No	No	8	7
167	1x60	I1x50	Shared	100	40	No	No	No	No	7	8
168	2x40	I1x50	Shared	100	100	Yes	Yes	No	No	8	8
169	2x37	2x40	Shared	100	100	No	No	Yes	Yes	6	8
170	2x42	3x45	Shared	100	100	Yes	Yes	No	No	8	6
171	2x42	3x46	Shared	100	100	Yes	Yes	No	No	8	9
172	2x42	3x49	Shared	100	100	Yes	Yes	Yes	Yes	8	9
173	2x43	7x53	Shared	100	100	No	No	Yes	Yes	8	9
174	2x45	3x42	Shared	100	100	No	No	No	No	9	8
175	2x45	4x46	Shared	100	100	No	No	No	No	9	8
176	2x45	4x50	Shared	100	100	No	No	No	No	9	9
177	2x46	3x42	Shared	100	100	No	Yes	No	No	9	8
178	2x46	7x49	Shared	100	100	No	Yes	Yes	No	9	9
179	2x50	3x39	Shared	100	100	Yes	Yes	No	No	9	9
180	2x50	7x46	Shared	100	100	Yes	Yes	No	No	9	9
181	2x50	7x49	Shared	100	100	Yes	Yes	Yes	No	9	9
182	2x53	3x35	Shared	100	100	No	No	No	No	8	7
183	2x57	7x42	Shared	100	100	No	Yes	No	No	6	6
184	2x61	2x65	Shared	100	20	No	No	No	No	6	4
185	2x62	2x66	Shared	100	100	No	No	No	No	5	4
186	2x63	E1	Shared	100	100	No	No	No	No	3	4
187	3x22	E2	Shared	100	100	No	No	Yes	Yes	3	5
188	3x25	E2	Shared	100	100	Yes	Yes	Yes	Yes	9	5
189	3x26	E2	Shared	100	100	No	No	Yes	Yes	5	5
190	3x29	E2	Shared	100	100	No	No	Yes	Yes	4	5
191	3x34	4x54	Shared	100	100	No	No	No	No	5	3
192	3x36	6x48	Shared	100	100	No	No	Yes	Yes	6	8
193	3x37	5x43	Shared	100	100	Yes	No	No	No	6	5
194	3x38	4x50	Shared	100	100	No	No	No	No	7	9
195	3x38	4x53	Shared	100	56.6667	No	No	No	No	7	8
196	3x41	4x49	Shared	100	100	No	No	No	No	5	6
197	3x42	4x49	Shared	100	100	No	No	No	No	8	6
198	3x51	3x55	Shared	100	100	Yes	No	No	No	8	6
199	3x51	5x57	Shared	100	100	Yes	No	No	No	8	6
200	3x51	5x60	Shared	100	100	Yes	No	No	Yes	8	5
201	3x55	3x56	Shared	100	100	No	No	No	No	6	5
202	4x60	E2	Shared	100	100	No	No	Yes	Yes	5	5
203	4x60	5x39	Shared	100	100	No	No	No	No	5	7
204	E2	E2	Shared	100	100	Yes	Yes	Yes	Yes	5	5
205	5x36	E2	Shared	100	100	No	No	Yes	Yes	4	5
206	5x39	E2	Shared	100	100	No	No	Yes	Yes	7	5
207	6x58	E2	Shared	100	100	Yes	No	Yes	Yes	3	5
208	E2	E3	Shared	100	100	Yes	Yes	Yes	Yes	5	1
209	7x34	E2	Shared	100	100	No	No	Yes	Yes	4	5
210	5x40	6x55	Shared	100	100	No	No	No	No	5	6
211	5x51	6x45	Shared	100	60	No	Yes	No	No	7	6
212	5x56	5x60	Shared	100	100	No	No	No	Yes	4	5
213	5x58	6x38	Shared	100	30	Yes	Yes	No	No	9	6
214	6x36	7x56	Shared	100	100	No	No	No	No	8	7
215	6x44	6x48	Shared	100	100	No	No	Yes	Yes	9	8
216	6x47	7x45	Shared	100	100	No	No	Yes	No	8	9
217	6x48	7x41	Shared	100	100	Yes	Yes	No	No	8	7
218	6x48	7x45	Shared	100	100	Yes	Yes	Yes	No	8	9
219	6x50	7x37	Shared	100	53.3333	No	No	No	No	9	4
220	6x54	7x37	Shared	100	100	No	No	No	No	4	4
221	7x45	7x49	Shared	100	100	Yes	No	Yes	No	9	9
222	8x47	8x50	Shared	100	40	No	Yes	No	No	8	8
223	1x43	2x57	Shared	100	60	No	No	No	Yes	7	6
224	3x47	5x58	Shared	100	100	No	No	Yes	Yes	9	9
225	3x54	5x61	Shared	100	100	No	No	No	No	9	9
226	5x42	5x46	Shared	100	100	No	No	No	No	5	5
227	5x44	6x56	Shared	100	41.5873	No	No	No	No	4	5
228	6x51	6x55	Shared	100	100	No	No	No	No	6	6
229	1x35	7x35	Shared	100	30	No	No	No	No	5	4
230	E1x49	E2	Shared	100	20	No	No	Yes	Yes	0	5
231	3x25	E1x50	Shared	100	100	Yes	Yes	Yes	No	9	0
232	E1x50	E2x50	Shared	100	100	Yes	No	No	No	0	0
233	3x25	E2x50	Shared	100	100	Yes	Yes	No	No	9	0
234	3x47	5x54	Shared	100	100	No	No	No	No	9	8
235	E2	E2x52	Shared	100	100	Yes	Yes	No	No	5	0
236	5x47	6x52	Shared	100	100	No	No	No	No	7	6
237	E3	E3	Shared	100	100	Yes	Yes	Yes	Yes	1	1
238	3x37	4x56	Shared	100	100	Yes	No	No	No	6	5
239	3x30	4x62	Shared	100	20	No	No	No	No	6	4
240	6x54	7x34	Shared	52.5	100	No	No	No	No	4	4
241	2x56	3x31	Shared	60	81.1111	No	No	No	No	4	4
242	5x37	6x59	Shared	65	100	No	No	No	Yes	4	3
243	1x45	7x47	Shared	70	50	No	No	No	No	4	6
244	1x39	2x61	Shared	70	41.4286	No	No	No	No	6	6
245	5x58	6x41	Shared	65	100	Yes	Yes	No	No	9	7
246	6x49	6x50	Shared	55	100	No	No	No	No	5	9
247	1x55	1x59	Shared	50	43.3333	No	No	No	No	5	5
248	E1x501	NT	Shared	20	20	No	No	Yes	Yes	0	5
249	5x38	E2	Shared	40	100	No	No	Yes	Yes	4	5
250	1x50	2x51	Shared	40	100	Yes	Yes	No	Yes	9	7
251	5x47	5x51	Shared	40	47.619	No	No	No	Yes	7	7
252	2x38	3x49	Shared	50	65	No	No	Yes	Yes	5	9
253	3x40	6x48	Shared	30	100	No	No	Yes	Yes	8	8
254	3x30	4x61	Shared	45	30	No	No	No	No	6	6
255	5x47	5x48	Shared	20	10	No	No	No	No	7	4
256	1x46	2x54	Shared	35	40	No	No	No	No	7	8
257	6x40	7x52	Shared	70	100	No	No	No	No	8	9
258	4x38	4x41	Shared	34.1667	100	No	No	No	No	9	6
259	5x58	6x37	Shared	45	100	Yes	Yes	No	No	9	8
260	3x24	E1x52	Shared	50	30	No	No	No	Yes	4	0
261	1x42	7x47	Shared	65	43.3333	No	No	No	No	6	6
262	3x34	4x57	Shared	15	100	No	No	No	No	5	7
263	1x38	7x39	Shared	50	100	No	No	No	No	5	5
264	5x60	5x64	Shared	35	100	No	Yes	No	Yes	5	6
265	5x68	I3	Shared	40	40	No	No	No	Yes	7	3
266	2x38	4x42	Shared	35	41.6667	No	No	No	No	5	7
267	I2x52	I2x56	Shared	27.5	100	No	No	No	No	5	4
268	3x21	3x24	Shared	40	50	No	No	No	No	6	4
269	1x54	2x48	Shared	20	40	No	No	No	No	7	7
270	3x56	I2x52	Shared	40	100	No	No	No	No	5	5
271	6x61	E3	Shared	27.5	100	No	No	Yes	Yes	3	1
272	1x54	2x47	Shared	15	100	No	No	No	No	7	9
273	2x59	E1x52	Shared	20	30	No	No	No	Yes	7	0
274	6x39	7x52	Shared	40	10.9524	No	No	No	No	6	9
275	5x41	5x45	Shared	41.6667	21.6667	No	No	No	No	4	3
276	1x51	2x51	Shared	50	44.7619	No	No	No	Yes	5	7
277	2x41	4x42	Shared	45	55	No	Yes	No	No	4	7
278	6x50	7x40	Shared	35	60	No	No	No	No	9	8
279	E1x48	NT	Shared	20	20	No	No	Yes	Yes	0	5
280	5x33	5x36	Shared	40	40	No	No	No	No	0	4
281	E1x49	E1x51	Shared	30	20	No	No	No	No	0	0
282	5x41	6x59	Shared	50	100	No	No	No	Yes	4	3
283	2x40	8x49	Shared	20	30	Yes	Yes	No	No	8	6
284	4x39	4x43	Shared	40	35.873	No	No	No	No	3	1
285	2x42	4x45	Shared	40	31.6667	Yes	Yes	No	No	8	6
286	8x48	8x51	Shared	40	53.3333	Yes	No	No	No	4	8
287	3x27	3x31	Shared	30	30	No	No	No	No	4	4
288	5x58	6x42	Shared	25	20	Yes	Yes	No	No	9	5
289	3x47	5x57	Shared	30	51.1111	No	No	No	No	9	6
290	6x32	8x48	Shared	40	20	No	No	Yes	No	8	4
291	1x36	2x65	Shared	30	40	No	Yes	No	No	5	4
292	1x42	7x43	Shared	10	100	No	No	No	No	6	4
293	6x43	7x52	Shared	35	50	No	No	No	No	7	9
294	2x52	3x35	Shared	25	50	No	No	No	No	7	7
295	5x35	E2	Shared	40	30	No	No	Yes	Yes	0	5
296	1x52	1x56	Shared	25	20.4762	No	No	No	Yes	7	8
297	1x59	8x57	Shared	21.6667	30	No	No	No	No	5	6
298	4x64	E2	Shared	20	100	No	No	Yes	Yes	0	5
299	5x51	5x55	Shared	20	50	No	Yes	No	No	7	5
300	2x41	I1x51	Shared	30	25	No	Yes	No	No	4	3
301	5x37	6x63	Shared	25	20	No	No	No	No	4	0
302	4x39	I1	Shared	40	30	No	No	No	No	3	7
303	3x44	5x53	Shared	35	100	No	No	No	No	6	5
304	1x29	1x30	Shared	30	30	No	No	No	No	4	4
305	1x56	8x54	Shared	21.6667	37.619	No	Yes	No	No	8	6
306	5x62	5x66	Shared	15	30	No	No	No	No	6	5
307	7x51	7x55	Shared	20	100	No	No	No	No	6	6
308	1x56	8x53	Shared	20	25	No	Yes	No	No	8	7
309	5x49	5x50	Shared	30	20	No	No	No	No	4	7
310	6x49	6x53	Shared	5	24.4444	No	No	No	No	5	5
311	I1x48	I1x51	Shared	28.3333	23.3333	No	No	No	No	5	3
312	8x51	8x55	Shared	30	8.33333	No	No	No	No	8	4
313	1x41	1x45	Shared	10	10	No	No	No	No	4	4
314	4x63	E2	Shared	10	12.1429	No	No	Yes	Yes	4	5
315	3x37	5x461	Shared	20	20	Yes	No	No	No	6	0
316	5x32	E2	Shared	25	20	No	No	Yes	Yes	0	5
317	4x48	4x52	Shared	10	2.22222	No	No	No	No	3	4
318	I2x50	I2x51	Shared	13.3333	20	No	No	No	No	8	7
319	E1x47	E1x48	Shared	5	13.3333	No	No	No	No	0	0
320	4x40	4x44	Shared	5	21.4286	No	No	No	No	4	3
321	8x58	8x62	Shared	0	3.33333	No	No	No	No	6	4
322	8x56	8x57	Shared	13.3333	5	No	No	No	No	5	6
323	7x57	7x58	Shared	0	0	No	No	No	No	0	0
324	7x58	7x59	Shared	0	0	No	No	No	No	0	0
325	7x32	NT	lipid_on	0	100	No	No	Yes	Yes	2	5
326	1x42	7x42	lipid_on	0	100	No	No	No	No	6	6
327	1x46	7x47	lipid_on	0	100	No	No	No	No	7	6
328	1x47	2x51	lipid_on	0	100	No	No	No	Yes	6	7
329	1x57	2x43	lipid_on	0	100	No	No	No	No	8	8
330	2x38	I2x57	lipid_on	0	100	No	No	No	No	5	6
331	2x39	3x49	lipid_on	0	100	No	No	Yes	Yes	8	9
332	2x46	3x43	lipid_on	0	100	No	Yes	No	No	9	8
333	2x57	2x61	lipid_on	0	100	No	Yes	No	No	6	6
334	2x57	Lig	lipid_on	0	100	No	Yes	Yes	Yes	6	0
335	2x60	3x28	lipid_on	0	100	No	No	No	No	4	5
336	3x25	3x29	lipid_on	0	100	Yes	Yes	No	No	9	4
337	3x36	Lig	lipid_on	0	100	No	No	Yes	Yes	6	0
338	3x41	5x50	lipid_on	0	100	No	No	No	No	5	7
339	3x43	7x53	lipid_on	0	100	No	No	Yes	Yes	8	9
340	3x44	5x50	lipid_on	0	100	No	No	No	No	6	7
341	3x46	7x53	lipid_on	0	100	No	No	Yes	Yes	9	9
342	3x49	I2x53	lipid_on	0	100	Yes	Yes	No	No	9	7
343	3x50	5x58	lipid_on	0	100	Yes	No	Yes	Yes	9	9
344	3x50	7x53	lipid_on	0	100	Yes	No	Yes	Yes	9	9
345	3x53	I2x53	lipid_on	0	100	No	No	No	No	8	7
346	3x55	5x64	lipid_on	0	100	No	No	No	Yes	6	6
347	4x52	4x56	lipid_on	0	100	No	No	No	No	4	5
348	7x31	E2	lipid_on	0	100	No	No	Yes	Yes	2	5
349	5x39	5x43	lipid_on	0	100	No	No	No	No	7	5
350	5x43	Lig	lipid_on	0	100	No	No	Yes	Yes	5	0
351	5x51	6x44	lipid_on	0	100	No	Yes	No	No	7	9
352	6x40	7x53	lipid_on	0	100	No	No	Yes	Yes	8	9
353	7x34	Lig	lipid_on	0	100	No	No	Yes	Yes	4	0
354	2x46	2x50	lipid_on	0	100	No	Yes	Yes	Yes	9	9
355	2x60	3x32	lipid_on	0	100	No	No	No	No	4	5
356	3x22	3x26	lipid_on	0	100	No	No	No	No	3	5
357	4x56	5x42	lipid_on	0	100	No	No	No	No	5	5
358	2x59	3x28	lipid_on	0	100	No	No	No	No	7	5
359	4x65	E2	lipid_on	0	100	No	No	Yes	Yes	0	5
360	E2	E2x51	lipid_on	0	100	Yes	Yes	No	No	5	0
361	7x33	E3	lipid_on	0	100	No	No	Yes	Yes	3	1
362	E3	NT	lipid_on	0	100	Yes	Yes	Yes	Yes	1	5
363	E2x51	E2x52	lipid_on	0	100	No	No	No	No	0	0
364	4x65	E2x52	lipid_on	0	100	No	No	No	No	0	0
365	6x31	6x32	lipid_on	0	100	No	Yes	No	No	5	8
366	7x35	Lig	lipid_on	0	50	No	No	Yes	Yes	4	0
367	2x49	3x38	lipid_on	0	40	No	No	No	No	8	7
368	5x40	Lig	lipid_on	0	33.3333	No	No	Yes	Yes	5	0
369	5x64	5x68	lipid_on	0	35	No	Yes	No	No	6	7
370	6x44	7x48	lipid_on	0	40	No	No	No	No	9	6
371	1x56	8x50	lipid_on	0	45	No	Yes	No	No	8	8
372	1x49	7x51	lipid_on	0	43.3333	No	No	No	No	8	6
373	2x56	3x32	lipid_on	0	51.6667	No	No	No	No	4	5
374	5x62	6x34	lipid_on	0	31.6667	No	No	No	No	6	8
375	6x37	8x47	lipid_on	0	20	No	No	No	Yes	8	8
376	1x39	7x39	lipid_on	0	70	No	No	No	No	6	5
377	5x34	E2	lipid_on	0	20	No	No	Yes	Yes	0	5
378	3x52	I2x53	lipid_on	0	40	No	No	No	No	5	7
379	3x34	4x53	lipid_on	0	43.0952	No	No	No	No	5	8
380	5x37	E2	lipid_on	0	40	No	No	Yes	Yes	4	5
381	3x26	4x61	lipid_on	0	60	No	No	No	No	5	6
382	3x54	5x64	lipid_on	0	40	No	No	No	Yes	9	6
383	2x41	4x39	lipid_on	0	40	No	Yes	No	No	4	3
384	1x53	2x47	lipid_on	0	46.1111	No	No	No	No	9	9
385	6x57	6x61	lipid_on	0	53.3333	No	No	No	No	4	3
386	1x32	1x36	lipid_on	0	20	No	No	No	Yes	5	5
387	5x44	6x55	lipid_on	0	42.5397	No	No	No	No	4	6
388	4x59	4x60	lipid_on	0	58.3333	No	No	No	No	5	5
389	6x36	8x47	lipid_on	0	20	No	No	No	Yes	8	8
390	1x31	7x36	lipid_on	0	40	No	No	No	No	5	4
391	5x61	5x65	lipid_on	0	60	No	No	No	No	9	8
392	2x40	8x47	lipid_on	0	40	Yes	Yes	No	Yes	8	8
393	2x53	7x46	lipid_on	0	35	No	No	No	No	8	9
394	3x44	3x48	lipid_on	0	40	No	No	No	No	6	6
395	I2x55	I2x56	lipid_on	0	30	No	No	No	No	4	4
396	I1x49	I1x50	lipid_on	0	46.6667	No	No	No	No	6	8
397	E1	E1x50	lipid_on	0	40	No	No	Yes	No	4	0
398	5x60	5x63	lipid_on	0	40.9524	No	Yes	No	No	5	3
399	5x69	6x28	lipid_on	0	21.6667	No	No	No	No	5	4
400	I2x51	I2x54	lipid_on	0	40	No	No	No	No	7	5
401	3x30	4x58	lipid_on	0	23.3333	No	No	No	No	6	4
402	5x66	6x30	lipid_on	0	43.3333	No	No	No	No	5	7
403	2x43	7x54	lipid_on	0	25	No	No	No	No	8	8
404	5x59	5x63	lipid_on	0	26.6667	No	No	No	No	3	3
405	5x67	6x30	lipid_on	0	20	No	Yes	No	No	5	7
406	6x58	7x30	lipid_on	0	40	Yes	No	No	No	3	3
407	1x35	7x36	lipid_on	0	30.4762	No	No	No	No	5	4
408	4x38	I2x52	lipid_on	0	20	No	No	No	No	9	5
409	5x64	5x67	lipid_on	0	35	No	Yes	No	Yes	6	5
410	6x61	7x26	lipid_on	0	20	No	No	Yes	No	3	0
411	7x28	E2	lipid_on	0	20	No	No	Yes	Yes	3	5
412	4x38	4x40	lipid_on	0	30	No	No	No	No	9	4
413	7x29	7x32	lipid_on	0	25	No	No	No	No	3	2
414	3x56	I2x54	lipid_on	0	20	No	No	No	No	5	5
415	2x51	2x55	lipid_on	0	25	No	Yes	No	No	7	4
416	6x31	I3	lipid_on	0	20	No	Yes	No	Yes	5	3
417	5x62	6x33	lipid_on	0	20	No	No	No	No	6	7
418	1x36	1x40	lipid_on	0	27.0635	No	Yes	No	No	5	5
419	1x36	1x37	lipid_on	0	20	No	Yes	No	No	5	5
420	2x62	E1x52	lipid_on	0	20	No	No	No	Yes	5	0
421	6x31	6x35	lipid_on	0	31.1111	No	Yes	No	No	5	7
422	5x69	6x30	lipid_on	0	20	No	No	No	No	5	7
423	1x47	1x48	lipid_on	0	30	No	No	No	No	6	4
424	1x57	7x62	lipid_on	0	20	No	No	No	No	8	0
425	1x61	2x41	lipid_on	0	20	No	No	No	Yes	0	4
426	7x61	7x62	lipid_on	0	20	No	No	No	No	0	0
427	7x60	7x63	lipid_on	0	20	No	No	No	No	0	0
428	1x55	1x60	lipid_on	0	20	No	No	No	No	5	7
429	1x54	1x58	lipid_on	0	21.1111	No	No	No	No	7	4
430	1x28	1x29	lipid_on	0	20	No	No	No	No	7	4
431	8x56	8x59	lipid_on	0	20	No	No	No	No	5	5
432	1x28	1x31	lipid_on	0	20	No	No	No	No	7	5
433	7x27	7x30	lipid_on	0	10	No	No	No	No	2	3
434	1x33	1x34	lipid_on	0	23.3333	No	No	No	No	4	5
435	1x34	7x36	lipid_on	0	20	No	No	No	No	5	4
436	1x63	1x64	lipid_on	0	30	No	No	No	No	0	0
437	3x21	3x23	lipid_on	0	13.8095	No	No	No	No	6	1
438	5x67	6x27	lipid_on	0	20	No	Yes	No	No	5	0
439	6x32	7x58	lipid_on	0	20	No	No	No	No	8	0
440	5x51	6x46	lipid_on	0	20	No	Yes	No	No	7	5
441	5x31	5x33	lipid_on	0	20	No	No	No	No	0	0
442	1x60	1x63	lipid_on	0	20	No	No	No	No	7	0
443	6x59	6x60	lipid_on	0	15.9524	No	Yes	No	No	3	4
444	1x61	1x65	lipid_on	0	20	No	No	No	No	0	0
445	5x72	I3	lipid_on	0	13.3333	No	No	No	Yes	0	3
446	2x67	E1x52	lipid_on	0	20	No	No	No	Yes	0	0
447	5x69	6x29	lipid_on	0	16.1111	No	No	No	No	5	5
448	6x26	6x31	lipid_on	0	20	No	No	No	Yes	0	5
449	4x47	4x48	lipid_on	0	0	No	No	No	No	4	3
450	5x52	5x56	lipid_on	0	10	No	No	No	No	3	4
451	1x40	1x44	lipid_on	0	10	No	No	No	No	5	5
452	8x51	8x52	lipid_on	0	13.3333	No	No	No	No	8	4
453	4x48	4x51	lipid_on	0	0	No	No	No	No	3	3
454	6x59	6x62	lipid_on	0	10	No	Yes	No	No	3	0
455	5x70	I3	lipid_on	0	10	No	No	No	Yes	5	3
456	7x55	I4	lipid_on	0	20	No	No	No	No	6	0
457	4x55	4x59	lipid_on	0	13.3333	No	No	No	No	3	5
458	4x65	4x68	lipid_on	0	10	No	No	No	No	0	0
459	8x60	8x61	lipid_on	0	10	No	No	No	No	5	3
460	1x59	1x62	lipid_on	0	10	No	No	No	No	5	0
461	8x56	8x60	lipid_on	0	10	No	No	No	No	5	5
462	7x64	I4	lipid_on	0	0	No	No	No	No	0	0
463	7x57	7x63	lipid_on	0	0	No	No	No	No	0	0
464	5x67	5x71	lipid_on	0	0.47619	No	Yes	No	No	5	3
465	6x43	6x461	lipid_on	0	0	No	No	No	No	7	0
466	4x63	4x67	lipid_on	0	10	No	No	No	No	4	0
467	6x25	6x26	lipid_on	0	0	No	No	No	No	0	0
468	7x25	7x29	lipid_on	0	0	No	No	No	No	0	3
469	5x73	I3	lipid_on	0	1.42857	No	No	No	Yes	0	3
470	8x55	8x58	lipid_on	0	0	No	No	No	No	4	6
471	6x23	6x26	lipid_on	0	3.33333	No	No	No	No	0	0
472	8x60	8x63	lipid_on	0	1.66667	No	No	No	No	5	2
473	1x65	1x66	lipid_on	0	0	No	No	No	No	0	0
474	2x68	E1x49	lipid_on	0	0	No	No	No	No	0	0
475	5x70	5x74	lipid_on	0	0	No	No	No	No	5	0
476	4x66	4x67	lipid_on	0	0	No	No	No	No	0	0
477	4x66	E2	lipid_on	0	0	No	No	Yes	Yes	0	5
478	5x76	I3	lipid_on	0	0	No	No	No	Yes	0	3
479	5x75	5x76	lipid_on	0	0	No	No	No	No	0	0
480	6x24	6x25	lipid_on	0	1.11111	No	No	No	No	0	0

Orange: nodes, hubs and links specific of lipid_off network

Green: nodes, hubs and links shared by both networks

Purple: nodes, hubs and links specific of lipid_on network

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Owner: the name of the network the hub belong to or "Shared" if the corresponding hub is present in both networks.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub in the corresponding network.

Num Of Links: the number of links of the corresponding hub in the corresponding network.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Owner	lipid_off Avg Int. Strength	lipid_on Avg Int. Strength	lipid_off Num Of Links	lipid_on Num Of Links	ConSurf
1	2x64	lipid_off	30	10	4	1	3
2	3x33	lipid_off	20	20	4	1	4
3	3x37	lipid_off	42.5	40	4	3	6
4	3x50	lipid_off	60	0	6	2	9
5	3x51	lipid_off	20	5	4	3	8
6	6x58	lipid_off	30	20	4	2	3
7	7x45	lipid_off	10	18.0952	4	3	9
8	7x49	lipid_off	25	0	5	3	9
9	8x48	lipid_off	0	0	4	2	4
10	E1x50	lipid_off	60	20	5	3	0
11	7x26	lipid_off	0	0	4	1	0
12	Lig	Shared	100	100	11	12	0
13	NT	Shared	70	50	14	7	5
14	1x50	Shared	0	15.5556	4	4	9
15	2x40	Shared	20	23.9683	5	4	8
16	2x42	Shared	20	3.33333	4	4	8
17	2x50	Shared	10	60	4	5	9
18	3x25	Shared	20	9.52381	4	4	9
19	3x49	Shared	10	20	4	4	9
20	E2	Shared	100	100	24	28	5
21	5x58	Shared	21.6667	60	6	6	9
22	6x48	Shared	65	68.3333	5	5	8
23	E3	Shared	30	56.6667	6	6	1
24	7x53	Shared	10	63.8889	4	5	9
25	1x36	lipid_on	0	0	1	4	5
26	1x56	lipid_on	0	0	3	4	8
27	2x41	lipid_on	0	0	3	4	4
28	2x46	lipid_on	0	38.3333	2	4	9
29	2x51	lipid_on	0	0	2	4	7
30	2x57	lipid_on	0	55.5556	3	4	6
31	5x51	lipid_on	0	30	3	5	7
32	5x60	lipid_on	0	10	3	4	5
33	5x64	lipid_on	0	0	2	5	6
34	5x67	lipid_on	0	0	1	4	5
35	I3	lipid_on	0	20	3	6	3
36	6x31	lipid_on	0	0	2	4	5
37	6x59	lipid_on	0	0	3	4	3
38	8x47	lipid_on	10	0	2	4	8
39	E1x52	lipid_on	10	20	3	4	0

Orange: nodes, hubs and links specific of lipid_off network

Green: nodes, hubs and links shared by both networks

Purple: nodes, hubs and links specific of lipid_on network

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Owner: the name of the network the link belong to or "Shared" if the corresponding link is present in both networks.

Recurrence: the relative Recurrence in the filtered pool of shortest paths.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Owner	lipid_off Recurrence	lipid_on Recurrence	lipid_off Hub1?	lipid_on Hub1?	lipid_off Hub2?	lipid_on Hub2?	ConSurf1	ConSurf2
1	1x35	1x39	lipid_off	23.0955	0	No	No	No	No	5	6
2	1x35	2x64	lipid_off	26.861	0	No	No	Yes	No	5	3
3	2x64	Lig	lipid_off	27.1405	0.746817	Yes	No	Yes	Yes	3	0
4	1x39	7x42	lipid_off	16.6371	0	No	No	No	No	6	6
5	1x49	7x50	lipid_off	12.5052	5.63015	No	No	No	No	8	9
6	1x50	7x50	lipid_off	13.8573	6.98448	Yes	Yes	No	No	9	9
7	6x48	7x41	lipid_off	99.0558	1.38916	Yes	Yes	No	No	8	7
8	6x51	7x41	lipid_off	99.1691	0	No	No	No	No	6	7
9	6x51	6x55	lipid_off	100	1.38916	No	No	No	No	6	6
10	6x55	Lig	lipid_off	68.0402	0	No	No	Yes	Yes	6	0
11	2x39	2x40	lipid_off	30.4037	0	No	No	Yes	Yes	8	8
12	2x39	3x50	lipid_off	33.6405	0	No	No	Yes	No	8	9
13	3x49	3x50	lipid_off	40.6088	0	Yes	Yes	Yes	No	9	9
14	3x46	6x37	lipid_off	57.8955	0	No	No	No	No	9	8
15	5x58	6x41	lipid_off	85.9538	1.08733	Yes	Yes	No	No	9	7
16	3x43	6x41	lipid_off	86.6072	0	No	No	No	No	8	7
17	3x43	6x44	lipid_off	87.204	0	No	No	No	No	8	9
18	2x38	4x42	lipid_off	10.0427	9.90984	No	No	No	No	5	7
19	5x40	6x55	lipid_off	33.8029	5.5218	No	No	No	No	5	6
20	5x40	E2	lipid_off	31.956	0	No	No	Yes	Yes	5	5
21	6x51	6x52	lipid_off	13.8573	0	No	No	No	No	6	6
22	5x47	6x52	lipid_off	12.5052	1.38916	No	No	No	No	7	6
23	7x34	E2	lipid_off	17.9212	1.45494	No	No	Yes	Yes	4	5
24	6x54	7x34	lipid_off	17.1281	8.12212	No	No	No	No	4	4
25	6x54	7x37	lipid_off	11.4854	6.78714	No	No	No	No	4	4
26	3x51	5x61	lipid_off	11.5043	0	Yes	No	No	No	8	9
27	3x54	5x61	lipid_off	10.1447	4.4809	No	No	No	No	9	9
28	E1x50	E1x52	lipid_off	12.4485	0	Yes	No	No	Yes	0	0
29	3x25	E2	lipid_off	10.7905	3.94691	Yes	Yes	Yes	Yes	9	5
30	3x25	E1x50	lipid_off	13.1208	4.3919	Yes	Yes	Yes	No	9	0
31	Lig	NT	lipid_off	14.7562	0	Yes	Yes	Yes	Yes	0	5
32	E2	E3	lipid_off	15.7495	5.63402	Yes	Yes	Yes	Yes	5	1
33	2x57	7x42	Shared	15.7193	10.9237	No	Yes	No	No	6	6
34	1x50	2x50	Shared	21.8114	21.3714	Yes	Yes	Yes	Yes	9	9
35	2x50	7x49	Shared	28.232	12.9977	Yes	Yes	Yes	No	9	9
36	7x45	7x49	Shared	55.3461	97.4384	Yes	No	Yes	No	9	9
37	6x48	7x45	Shared	58.3979	96.9663	Yes	Yes	Yes	No	8	9
38	2x42	3x49	Shared	54.7494	17.9081	Yes	Yes	Yes	Yes	8	9
39	2x42	3x46	Shared	56.9778	21.0811	Yes	Yes	No	No	8	9
40	5x58	6x37	Shared	61.053	22.4858	Yes	Yes	No	No	9	8
41	6x44	6x48	Shared	87.7932	12.2548	No	No	Yes	Yes	9	8
42	2x38	3x49	Shared	13.4079	11.9297	No	No	Yes	Yes	5	9
43	2x46	3x42	Shared	15.2019	22.6251	No	Yes	No	No	9	8
44	2x46	7x49	Shared	16.5389	84.6612	No	Yes	Yes	No	9	9
45	E2	Lig	Shared	36.1861	45.908	Yes	Yes	Yes	Yes	5	0
46	3x47	5x58	Shared	33.8822	78.7757	No	No	Yes	Yes	9	9
47	3x47	5x57	Shared	29.0327	77.5607	No	No	No	No	9	6
48	3x51	5x57	Shared	27.8015	76.9415	Yes	No	No	No	8	6
49	1x60	I1x50	Shared	13.1133	10.1807	No	No	No	No	7	8
50	2x40	I1x50	Shared	22.14	11.6511	Yes	Yes	No	No	8	8
51	2x57	2x61	lipid_on	0	12.3283	No	Yes	No	No	6	6
52	2x57	Lig	lipid_on	0	25.7517	No	Yes	Yes	Yes	6	0
53	3x36	6x48	lipid_on	9.17778	93.4837	No	No	Yes	Yes	6	8
54	3x36	Lig	lipid_on	0	92.8723	No	No	Yes	Yes	6	0
55	3x43	7x53	lipid_on	0	99.7949	No	No	Yes	Yes	8	9
56	2x46	3x43	lipid_on	0	100	No	Yes	No	No	9	8
57	2x40	8x47	lipid_on	0	14.4759	Yes	Yes	No	Yes	8	8
58	6x37	8x47	lipid_on	0	21.7854	No	No	No	Yes	8	8
59	3x50	5x58	lipid_on	0	90.984	Yes	No	Yes	Yes	9	9
60	3x50	7x53	lipid_on	0	91.1349	Yes	No	Yes	Yes	9	9
61	3x46	7x53	lipid_on	0	22.1994	No	No	Yes	Yes	9	9
62	2x45	3x42	lipid_on	8.40352	12.2548	No	No	No	No	9	8
63	2x60	3x28	lipid_on	0	10.4632	No	No	No	No	4	5
64	2x60	Lig	lipid_on	0.728935	16.1669	No	No	Yes	Yes	4	0
65	3x37	4x56	lipid_on	3.70133	11.0397	Yes	No	No	No	6	5
66	3x37	5x43	lipid_on	8.31287	12.9397	Yes	No	No	No	6	5
67	5x43	Lig	lipid_on	0	12.959	No	No	Yes	Yes	5	0
68	3x51	3x55	lipid_on	9.27598	41.5896	Yes	No	No	No	8	6
69	3x51	5x60	lipid_on	7.02119	35.1855	Yes	No	No	Yes	8	5
70	3x55	5x64	lipid_on	0	31.4902	No	No	No	Yes	6	6
71	5x60	5x64	lipid_on	4.23386	30.9097	No	Yes	No	Yes	5	6
72	3x55	3x56	lipid_on	7.90875	12.8623	No	No	No	No	6	5
73	6x31	6x32	lipid_on	0	17.4167	No	Yes	No	No	5	8
74	6x31	I3	lipid_on	0	25.9297	No	Yes	No	Yes	5	3
75	5x68	I3	lipid_on	4.32828	34.8412	No	No	No	Yes	7	3
76	5x64	5x68	lipid_on	0	36.9771	No	Yes	No	No	6	7
77	5x67	6x30	lipid_on	0	14.0696	No	Yes	No	No	5	7
78	5x64	5x67	lipid_on	0	18.7943	No	Yes	No	Yes	6	5
79	2x46	2x50	lipid_on	0	15.8225	No	Yes	Yes	Yes	9	9

Here, those paths that begin and end at given residue pair(s) or that pass through a residue are used to generate a novel metapath. Such a path filtering is particularly recommended if some information on allosteric residues is available. The selection syntax for a residue pair ("Pairs") is C:C:c534,A:A:?600 (the lower-case "c" stands for cytosine and "?" indicates any non standard amino acid or nucleotide residue). Selection of more than one apical residue pair has the following syntax: C:C:c534,A:A:?600,C:C:c534,A:A:E41. Only one residue can be selected as a tail ("Tail"). For midway residue(s), each residue must be separated by a comma as well e.g. A:A:?600,A:A:E41.

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Node1	Node2	Owner	Net1LinkStrength	Net2LinkStrength	Comm1	Comm2	Node1Shell	Node2Shell
2x60	Lig	Shared	10.8539	5.68138	0	0	1	0
2x64	Lig	Shared	4.4205	5.15023	1	0	1	0
3x29	Lig	Shared	5.56742	3.16207	1	1	1	0
3x32	Lig	lipid_off	10.0023	0	0	0	1	0
3x33	Lig	Shared	5.51317	7.7937	0	0	1	0
E2	Lig	Shared	9.914	9.93233	1	1	1	0
6x55	Lig	lipid_off	4.56267	0	0	0	1	0
7x38	Lig	Shared	10.8258	5.67712	0	0	1	0
NT	NT	Shared	26.0698	18.4444	1	1	1	1
E2	NT	Shared	29.4972	18.7026	1	1	1	1
2x64	NT	lipid_off	3.7345	0	1	0	1	1
3x25	NT	lipid_off	4.70417	0	1	1	2	1
7x31	NT	lipid_off	4.082	0	1	0	2	1
1x39	7x42	lipid_off	4.13367	0	0	0	2	2
2x57	7x42	Shared	5.035	4.20832	0	0	1	2
3x22	E2	Shared	7.04158	4.64731	0	1	2	1
3x25	E2	Shared	12.2572	6.103	1	1	2	1
3x26	E2	Shared	7.41617	3.8266	0	1	2	1
3x29	E2	Shared	4.284	5.27722	1	1	1	1
3x33	5x43	lipid_off	3.831	0	0	0	1	1
3x36	6x48	Shared	9.14142	3.99965	0	0	1	2
3x37	5x43	Shared	4.308	3.23033	0	0	2	1
4x60	E2	Shared	3.6555	6.09498	1	1	2	1
4x60	5x39	Shared	8.61408	7.12736	1	1	2	2
E2	E2	Shared	66.4906	44.3584	1	1	1	1
5x36	E2	Shared	10.4912	8.67044	1	1	2	1
5x39	E2	Shared	7.964	7.52839	1	1	2	1
6x58	E2	Shared	9.86908	7.16575	1	1	2	1
E2	E3	Shared	3.6805	3.10067	1	1	1	2
7x34	E2	Shared	4.86542	4.72339	1	1	1	1
5x40	E2	lipid_off	3.639	0	1	0	1	1
5x40	6x55	Shared	4.74275	4.75994	1	0	1	1
5x40	6x59	lipid_off	6.67925	0	1	0	1	2
Lig	NT	lipid_off	5.37183	0	1	1	0	1
7x39	Lig	lipid_off	4.9555	0	0	0	1	0
1x35	1x39	lipid_off	3.7725	0	0	0	2	2
1x43	2x57	Shared	4.75467	2.26297	0	0	2	1
6x51	6x55	Shared	5.9635	6.28913	0	0	2	1
7x27	NT	lipid_off	5.039	0	0	0	2	1
1x27	7x31	lipid_off	4.11025	0	0	0	2	2
1x27	7x35	lipid_off	3.79483	0	0	0	2	1
1x35	2x64	lipid_off	7.33958	0	0	0	2	1
1x35	7x35	Shared	3.8865	1.40562	0	0	2	1
2x63	2x64	lipid_off	3.67425	0	0	0	2	1
E1x49	E2	Shared	4.69125	1.196	1	1	2	1
3x36	3x37	lipid_off	3.9155	0	0	0	1	2
E2	E2x52	Shared	4.10133	3.861	1	1	1	2
E2x51	Lig	lipid_off	3.62225	0	0	1	1	0
6x58	7x31	lipid_off	4.46317	0	1	1	2	2
6x58	7x34	lipid_off	11.4186	0	1	1	2	1
E3	E3	Shared	5.763	5.23743	1	1	2	2
6x54	7x34	Shared	3.59967	3.27298	0	0	2	1
3x29	4x65	lipid_off	3.575	0	1	1	1	2
1x31	7x35	lipid_off	3.5675	0	0	0	2	1
5x37	6x59	Shared	3.54475	3.00843	0	1	2	2
1x39	2x61	Shared	3.51267	2.86694	0	0	2	2
3x33	4x61	lipid_off	3.48425	0	0	0	1	2
E1x501	NT	Shared	3.2965	2.05122	0	0	2	1
5x38	E2	Shared	3.288	3.08553	0	0	2	1
4x59	E2	lipid_off	3.11	0	0	0	2	1
3x33	4x57	lipid_off	3.083	0	0	0	1	2
1x38	7x39	Shared	2.81967	5.4625	0	0	2	1
1x28	NT	lipid_off	2.563	0	1	0	2	1
7x28	NT	lipid_off	2.518	0	1	0	2	1
E1x48	NT	Shared	2.4485	0.8105	1	1	2	1
2x53	2x57	lipid_off	2.37767	0	0	0	2	1
7x28	7x32	lipid_off	2.127	0	1	0	2	2
5x35	E2	Shared	1.8425	1.635	1	0	2	1
4x64	E2	Shared	1.6425	9.013	0	0	2	1
4x63	E2	Shared	1.0095	0.702294	0	1	2	1
5x34	5x35	lipid_off	1.002	0	0	0	2	2
5x32	E2	Shared	0.9225	2.75	0	0	2	1
6x64	E2	lipid_off	0.698	0	1	0	2	1
7x24	NT	lipid_off	0.306	0	1	0	2	1
5x28	NT	lipid_off	0.288	0	0	0	2	1
7x32	NT	lipid_on	0	3.58995	0	1	2	1
2x57	2x61	lipid_on	0	3.22021	0	0	1	2
2x57	Lig	lipid_on	0	4.12133	0	0	1	0
2x60	3x28	lipid_on	0	5.40331	0	0	1	2
3x25	3x29	lipid_on	0	4.36507	1	1	2	1
3x36	Lig	lipid_on	0	3.96804	0	0	1	0
7x31	E2	lipid_on	0	3.40783	1	0	2	1
5x39	5x43	lipid_on	0	2.98939	1	1	2	1
5x43	Lig	lipid_on	0	7.04382	0	0	1	0
7x34	Lig	lipid_on	0	4.32764	1	1	1	0
2x60	3x32	lipid_on	0	3.34566	0	0	1	1
3x22	3x26	lipid_on	0	4.12297	0	1	2	2
4x65	E2	lipid_on	0	4.466	0	1	2	1
E2	E2x51	lipid_on	0	4.24933	1	1	1	1
E3	NT	lipid_on	0	3.51003	1	1	2	1
E2x51	E2x52	lipid_on	0	3.322	0	1	1	2
4x65	E2x52	lipid_on	0	3.17	0	1	2	2
7x35	Lig	lipid_on	0	2.80081	0	0	1	0
5x40	Lig	lipid_on	0	2.77233	1	0	1	0
2x56	3x32	lipid_on	0	2.70889	0	0	2	1
1x39	7x39	lipid_on	0	2.65962	0	0	2	1
5x34	E2	lipid_on	0	2.515	0	0	2	1
5x37	E2	lipid_on	0	2.47685	0	1	2	1
3x26	4x61	lipid_on	0	2.47086	0	1	2	2
5x44	6x55	lipid_on	0	2.35957	0	0	2	1
4x59	4x60	lipid_on	0	2.29931	0	0	2	2
7x28	E2	lipid_on	0	1.543	1	0	2	1
1x28	1x31	lipid_on	0	1.06217	1	0	2	2
4x66	E2	lipid_on	0	0.137	0	1	2	1

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Difference Members
	Id	Description
	lipid_off	cannabinoid_off paf_off lpl_off prostanoid_off leukotriene_off
	lipid_on	cannabinoid_on ffa_on lpl_on prostanoid_on leukotriene_on

Network Difference
Value	lipid_off	lipid_on
I_min	3.61392	2.95627
Number of Linked Nodes	310	313
Number of Specific Nodes	18 (5.81%)	21 (6.71%)
Number of Shared Nodes	292 (94.19%)	292 (93.29%)
Number of Links	324	328
Number of Specific Links	152 (46.91%)	156 (47.56%)
Number of Shared Links	172 (53.09%)	172 (52.44%)
Number of Hubs	24	28
Number of Specific Hubs	11 (45.83%)	15 (53.57%)
Number of Shared Hubs	13 (54.17%)	13 (46.43%)
Average % Shared Neighbours (Jaccard)	37.87
Average % Shared Neighbours (Otsuka)	46.30
Average % Shared Neighbours (Overlap Coefficient)	54.94
Average % Shared Cliques (k3-6)	80.36
Graphlets Similarity	0.443733

Paths Difference
Value	lipid_off	lipid_on
Number Of Nodes in MetaPath	50	46
Specific Nodes in MetaPath	24 (48.00%)	20 (43.48%)
Shared Nodes in MetaPath	292 (94.19%)	292 (94.19%)
Number Of Links MetaPath	50	47
Specific Links in MetaPath	32 (64.00%)	29 (61.70%)
Shared Links in MetaPath	172 (53.09%)	172 (53.09%)
Number of Shortest Paths	50163	49290
Length Of Smallest Path	3	3
Average Path Length	14.3117	14.4203
Length of Longest Path	34	31
Minimum Path Strength	0.454833	0.369339
Average Path Strength	4.7161	4.17795
Maximum Path Strength	19.9942	13.6865
Minimum Path Correlation	0.702833	0.702127
Average Path Correlation	0.895039	0.898315
Maximum Path Correlation	0.985333	0.988254
Minimum % Of Corr. Nodes	3.125	3.57143
Average % Of Corr. Nodes	37.9424	37.264
Maximum % Of Corr. Nodes	100	100
Minimum Path Hubs %	0	0
Average Path Hubs %	34.1201	35.8435
Maximum Path Hubs %	100	100

Details about the values in these tables can be found in the corresponding documentation page .

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Download lipid_off_on.zip<

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