Orange: nodes, hubs and links specific of m1_on_gp network

Green: nodes, hubs and links shared by both networks

Purple: nodes, hubs and links specific of m1_off network

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Owner: the name of the network the hub belong to or "Shared" if the corresponding hub is present in both networks.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub in the corresponding network.

Num Of Links: the number of links of the corresponding hub in the corresponding network.

ConSurf: this column reports the ConSurf conservation grades of each hub.


Index Hub Owner m1_on_gp Avg Int. Strength m1_off Avg Int. Strength m1_on_gp Num Of Links m1_off Num Of Links ConSurf
1b.1x14 m1_on_gp2.01250404
2b.l1x3 m1_on_gp8.6240509
3b.b2x1 m1_on_gp7.5740508
4b.b2x3 m1_on_gp4.4880506
5b.b2x5 m1_on_gp5.621670607
6b.b3x3 m1_on_gp4.8550408
7b.l3x2 m1_on_gp4.750509
8b.b4x2 m1_on_gp4.660408
9b.b4x6 m1_on_gp9.328570709
10b.b5x2 m1_on_gp5.91750407
11b.b5x5 m1_on_gp5.27250405
12b.b5x7 m1_on_gp7.1050407
13b.l5x5 m1_on_gp6.825710709
14b.b6x1 m1_on_gp3.77750409
15b.b6x5 m1_on_gp3.9550406
16b.b7x1 m1_on_gp7.3550404
17b.l7x2 m1_on_gp4.710409
18b.b8x1 m1_on_gp3.73750408
19b.b8x3 m1_on_gp4.410406
20b.b8x4 m1_on_gp4.966670606
21b.l9x6 m1_on_gp4.5380508
22b.b10x4 m1_on_gp6.27250406
23b.b10x5 m1_on_gp5.59750409
24b.b11x4 m1_on_gp5.74250409
25b.l11x2 m1_on_gp7.75750409
26b.b12x3 m1_on_gp4.2350408
27b.b12x5 m1_on_gp4.1850406
28b.b12x6 m1_on_gp9.9720508
29b.b13x5 m1_on_gp5.00750404
30b.b13x7 m1_on_gp9.6080507
31b.l13x3 m1_on_gp7.5420509
32b.l13x7 m1_on_gp4.470509
33b.b14x1 m1_on_gp4.2750408
34b.l15x1 m1_on_gp4.7040507
35b.l15x2 m1_on_gp7.8660509
36b.b16x4 m1_on_gp8.4280506
37b.b16x6 m1_on_gp8.790508
38b.b17x3 m1_on_gp5.99250405
39b.b17x7 m1_on_gp8.57750408
40b.l17x3 m1_on_gp8.908330609
41b.l17x6 m1_on_gp7.56250409
42b.b18x3 m1_on_gp5.0950408
43b.b18x5 m1_on_gp4.65250405
44b.l18x1 m1_on_gp7.230706
45b.l18x2 m1_on_gp6.0150407
46b.l18x3 m1_on_gp8.250405
47b.b19x2 m1_on_gp6.886670606
48b.b19x4 m1_on_gp4.9180508
49b.l19x1 m1_on_gp5.4750409
50b.l19x2 m1_on_gp7.8850409
51b.b20x2 m1_on_gp4.633330606
52b.b20x4 m1_on_gp8.7980508
53b.b20x6 m1_on_gp7.6440506
54b.b21x2 m1_on_gp5.18750406
55b.b21x7 m1_on_gp5.4620505
56b.l21x5 m1_on_gp5.3650404
57b.b22x5 m1_on_gp4.9220507
58b.l22x5 m1_on_gp6.460509
59b.b23x2 m1_on_gp5.00750406
60b.b23x6 m1_on_gp7.2850607
61b.l23x1 m1_on_gp8.780406
62b.l23x2 m1_on_gp8.13250408
63b.b24x4 m1_on_gp5.64250406
64b.b24x5 m1_on_gp3.19250405
65b.b24x6 m1_on_gp7.64250408
66b.b24x7 m1_on_gp7.59250409
67b.b25x3 m1_on_gp7.930405
68b.l25x3 m1_on_gp10.330409
69b.l25x6 m1_on_gp14.6550408
70b.l27x1 m1_on_gp12.060709
71b.l27x2 m1_on_gp8.56750409
72b.b28x3 m1_on_gp4.97250407
73b.b28x4 m1_on_gp9.11750406
74b.b28x5 m1_on_gp4.440405
75b.b28x6 m1_on_gp9.16250409
76b.b28x7 m1_on_gp7.4350409
77g.h2x11 m1_on_gp9.430406
78g.ctx3 m1_on_gp6.3760509
79g.ctx6 m1_on_gp4.6460506
80g.ctx14 m1_on_gp5.98750409
81g.ctx16 m1_on_gp5.083330908
821x46 m1_on_gp4.7855.86438
831x48 m1_on_gp2.32752.95415
842x38 m1_on_gp4.25754.79333437
852x63 m1_on_gp4.90257.24427
863x43 m1_on_gp4.9666.57333538
874x64 m1_on_gp9.498.02667437
884x68 m1_on_gp4.5053.95434
895x48 m1_on_gp5.1365.3527
905x58 m1_on_gp6.632.70333639
915x62 m1_on_gp6.58250407
926x40 m1_on_gp4.11255.995428
936x49 m1_on_gp3.8053.19333437
946x51 m1_on_gp6.9449.63667538
957x39 m1_on_gp8.3988.49518
967x53 m1_on_gp5.3510.8639
97CT.W437 m1_on_gp6.148.68533
98G.H1.01 m1_on_gp6.0450409
99G.H1.12 m1_on_gp7.2050408
100G.S2.03 m1_on_gp7.2450409
101G.S2.04 m1_on_gp8.3950407
102G.S2.06 m1_on_gp7.2460508
103G.S3.04 m1_on_gp7.78750407
104G.S3.05 m1_on_gp4.99250407
105G.S3.07 m1_on_gp6.1820509
106G.s3h2.03 m1_on_gp6.3260509
107G.H2.06 m1_on_gp5.441670609
108G.H2.07 m1_on_gp6.438330609
109G.H2.10 m1_on_gp5.3080507
110G.h2s4.01 m1_on_gp7.9850409
111G.S4.01 m1_on_gp4.280408
112G.S4.04 m1_on_gp7.830409
113G.s4h3.03 m1_on_gp5.4380507
114G.s4h3.04 m1_on_gp7.760508
115G.H3.01 m1_on_gp9.03250409
116G.H3.09 m1_on_gp7.18250409
117G.H3.15 m1_on_gp3.63750408
118G.H3.17 m1_on_gp5.130405
119G.S5.03 m1_on_gp4.650408
120G.S5.05 m1_on_gp5.00750409
121G.s5hg.01 m1_on_gp4.7320509
122G.HG.15 m1_on_gp4.95750406
123G.hgh4.02 m1_on_gp4.230508
124G.hgh4.05 m1_on_gp6.1720506
125G.H4.12 m1_on_gp3.8950405
126G.S6.02 m1_on_gp5.883330608
127G.S6.05 m1_on_gp6.66750405
128G.s6h5.01 m1_on_gp5.73750409
129G.H5.08 m1_on_gp6.528330608
1301x39 Shared4.69255.7175446
1311x50 Shared5.5056.8449
1321x60 Shared8.7557.53448
1332x42 Shared7.186.445448
1342x50 Shared6.27756.9275449
1352x53 Shared5.075.42458
1362x60 Shared7.3849.5175547
137E1x50 Shared6.466676.26571679
1383x28 Shared6.12257.652457
1393x33 Shared9.2583310.688658
1403x37 Shared6.271675.698658
1413x50 Shared11.0255.585449
142I2x57 Shared8.548.822658
1434x57 Shared8.1687.826558
1444x61 Shared3.6654.0725447
145E2.R171 Shared8.33259.2625447
146E2x52 Shared6.3256.158457
147E2.F182 Shared5.2846.6275546
1485x47 Shared9.9510.8025649
1495x68 Shared6.2555.7458
1506x44 Shared5.6427.656559
1516x48 Shared8.718.51625888
1527x34 Shared3.59256.582457
1537x38 Shared7.1510.13567
1547x42 Shared9.353337.36429678
1558x50 Shared8.317.965449
156Lig Shared8.576928.6721413140
157NT.K20 m1_off04.525040
1582x57 m1_off7.706676.25348
1593x32 m1_off9.737.7625349
1603x51 m1_off12.896.16368
1613x52 m1_off7.2857.3275247
1623x56 m1_off4.0155.88247
163I2x53 m1_off13.36677.006359
1644x50 m1_off5.716675.5925349
165E2.L183 m1_off7.146.56147
1665x41 m1_off4.9255.9725247
1676x47 m1_off4.706674.215348
168E3.V395 m1_off3.2855.975246
1698x54 m1_off4.933336.6925349
   
Orange: nodes, hubs and links specific of m1_on_gp network

Green: nodes, hubs and links shared by both networks

Purple: nodes, hubs and links specific of m1_off network

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Owner: the name of the network the link belong to or "Shared" if the corresponding link is present in both networks.

Recurrence: the relative Recurrence in the filtered pool of shortest paths.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.


Index Node1 Node2 Owner m1_on_gp Recurrence m1_off Recurrence m1_on_gp Hub1? m1_off Hub1? m1_on_gp Hub2? m1_off Hub2? ConSurf1 ConSurf2
1b.b15x2 b.b18x5 m1_on_gp17.70330NoNoYesNo65
2b.b18x5 b.l18x4 m1_on_gp28.99660YesNoNoNo57
3b.l18x3 b.l18x4 m1_on_gp29.74330YesNoNoNo57
4b.l18x1 b.l18x3 m1_on_gp32.34020YesNoYesNo65
5b.b22x5 b.l18x1 m1_on_gp34.57770YesNoYesNo76
6b.b22x5 b.b23x2 m1_on_gp37.20060YesNoYesNo76
7b.b21x7 b.b23x2 m1_on_gp38.68680YesNoYesNo56
8b.b21x5 b.b21x7 m1_on_gp16.25610NoNoYesNo45
9b.b21x5 b.h2x1 m1_on_gp14.37360NoNoNoNo45
10b.b21x4 b.h2x1 m1_on_gp12.4890NoNoNoNo55
11b.b20x7 b.b21x4 m1_on_gp11.73470NoNoNoNo95
12b.b20x7 b.l20x3 m1_on_gp10.97990NoNoNoNo97
13b.l20x3 g.h2x1 m1_on_gp10.60250NoNoNoNo78
14b.b21x2 g.h2x1 m1_on_gp10.22490YesNoNoNo68
15b.b18x5 b.l20x1 m1_on_gp10.54670YesNoNoNo56
16b.b21x7 b.b24x6 m1_on_gp55.29930YesNoYesNo58
17b.b23x6 b.b24x6 m1_on_gp56.00960YesNoYesNo78
18b.b23x6 b.l23x2 m1_on_gp60.46390YesNoYesNo78
19b.l21x7 b.l23x2 m1_on_gp63.39430NoNoYesNo58
20b.l21x7 b.l23x1 m1_on_gp63.76020NoNoYesNo56
21b.l23x1 b.l25x6 m1_on_gp25.79260YesNoYesNo68
22b.l25x6 b.l27x1 m1_on_gp26.15020YesNoYesNo89
23b.b2x1 b.l27x1 m1_on_gp22.04360YesNoYesNo89
24G.H2.10 b.b2x1 m1_on_gp21.08550YesNoYesNo78
25G.H2.10 b.l7x2 m1_on_gp21.79690YesNoYesNo79
26G.H2.07 b.l7x2 m1_on_gp24.02940YesNoYesNo99
27G.H2.04 G.H2.07 m1_on_gp81.95950NoNoYesNo99
28G.H2.04 G.H3.12 m1_on_gp82.23370NoNoNoNo97
29G.H3.12 G.S4.04 m1_on_gp82.26550NoNoYesNo79
30G.H3.09 G.S4.04 m1_on_gp83.37080YesNoYesNo99
31G.H3.09 G.S5.04 m1_on_gp84.19780YesNoNoNo98
32G.S5.04 G.S5.06 m1_on_gp84.26630NoNoNoNo88
33G.S5.06 G.s4h3.01 m1_on_gp83.9830NoNoNoNo87
34G.HG.04 G.s4h3.01 m1_on_gp85.0190NoNoNoNo87
35G.HG.04 G.s4h3.04 m1_on_gp85.09150NoNoYesNo88
36G.HG.07 G.s4h3.04 m1_on_gp85.59980NoNoYesNo98
37G.HG.07 G.s4h3.02 m1_on_gp85.99910NoNoNoNo99
38G.s4h3.02 G.s5hg.01 m1_on_gp86.07360NoNoYesNo99
39G.S5.07 G.s5hg.01 m1_on_gp88.77430NoNoYesNo99
40G.S4.05 G.S5.07 m1_on_gp29.79080NoNoNoNo79
41G.H1.04 G.S4.05 m1_on_gp29.80650NoNoNoNo77
42G.H1.04 G.S5.05 m1_on_gp40.96730NoNoYesNo79
43G.S5.03 G.S5.05 m1_on_gp70.30840YesNoYesNo89
44G.H5.10 G.S5.03 m1_on_gp1000NoNoYesNo78
45G.H5.10 G.S6.02 m1_on_gp99.9120NoNoYesNo78
46G.H5.13 G.S6.02 m1_on_gp98.95080NoNoYesNo78
475x68 G.H5.13 m1_on_gp98.92850YesYesNoNo87
485x68 G.H5.20 m1_on_gp98.49340YesYesNoNo88
495x65 G.H5.20 m1_on_gp97.9560NoNoNoNo88
505x65 5x66 m1_on_gp97.86610NoNoNoNo87
515x62 5x66 m1_on_gp97.68620YesNoNoNo77
525x62 6x37 m1_on_gp97.41560YesNoNoNo79
535x58 6x37 m1_on_gp97.14440YesNoNoNo99
543x47 5x58 m1_on_gp52.57530NoNoYesNo99
553x47 5x57 m1_on_gp16.00480NoNoNoNo98
56b.l21x8 b.l23x1 m1_on_gp38.85190NoNoYesNo46
57b.l19x1 b.l21x8 m1_on_gp39.0610YesNoNoNo94
58G.H2.06 b.l19x1 m1_on_gp38.29820YesNoYesNo99
59G.H2.06 b.l9x6 m1_on_gp38.91860YesNoYesNo98
60G.s3h2.03 b.l9x6 m1_on_gp21.75630YesNoYesNo98
61G.H2.07 G.s3h2.03 m1_on_gp37.8590YesNoYesNo99
62G.H2.02 b.l9x6 m1_on_gp20.3520NoNoYesNo88
63G.H2.02 G.H2.07 m1_on_gp20.4440NoNoYesNo89
64b.b4x4 b.b4x6 m1_on_gp10.89380NoNoYesNo89
65G.HN.47 b.b4x4 m1_on_gp10.72030NoNoNoNo68
66G.HN.47 b.b4x2 m1_on_gp10.74030NoNoYesNo68
67G.HN.50 b.b4x2 m1_on_gp11.75930NoNoYesNo58
68G.HN.50 G.HN.53 m1_on_gp11.77750NoNoNoNo51
69G.HN.53 G.hns1.03 m1_on_gp11.79570NoNoNoNo14
70G.hns1.03 I2x55 m1_on_gp11.81480NoNoNoNo46
71G.S3.01 I2x55 m1_on_gp11.83450NoNoNoNo46
72G.H5.08 G.S3.01 m1_on_gp11.76590YesNoNoNo84
73G.H5.08 G.S2.08 m1_on_gp12.09710YesNoNoNo85
74G.H1.12 G.S2.08 m1_on_gp12.21950YesNoNoNo85
75G.H1.12 G.S2.06 m1_on_gp12.28470YesNoYesNo88
76G.H1.08 G.S2.06 m1_on_gp12.52180NoNoYesNo98
77G.H1.04 G.H1.08 m1_on_gp12.10830NoNoNoNo79
78G.S5.07 G.s6h5.01 m1_on_gp59.06510NoNoYesNo99
79G.S6.04 G.s6h5.01 m1_on_gp58.7880NoNoYesNo99
80G.S5.05 G.S6.04 m1_on_gp29.41360YesNoNoNo99
81G.H5.06 G.S6.04 m1_on_gp29.40660NoNoNoNo49
82G.H5.06 G.S5.03 m1_on_gp29.40530NoNoYesNo48
83b.b11x4 b.l9x3 m1_on_gp19.95060YesNoNoNo99
84b.b10x3 b.b6x2 m1_on_gp15.43040NoNoNoNo88
85b.b10x2 b.b6x2 m1_on_gp15.16670NoNoNoNo68
86b.b11x2 b.b11x4 m1_on_gp10.72630NoNoYesNo79
87G.s3h2.03 b.l9x5 m1_on_gp18.45920YesNoNoNo98
88b.l9x4 b.l9x5 m1_on_gp18.36050NoNoNoNo58
89b.l11x2 b.l9x4 m1_on_gp18.24260YesNoNoNo95
90b.b10x2 b.b14x3 m1_on_gp12.24160NoNoNoNo65
91b.b11x3 b.b14x3 m1_on_gp11.99570NoNoNoNo55
92b.b11x3 b.b12x5 m1_on_gp11.73090NoNoYesNo56
933x40 Lig m1_on_gp32.28180NoNoYesYes90
943x40 6x44 m1_on_gp32.52680NoNoYesYes99
953x43 7x53 m1_on_gp40.15380YesNoYesNo89
965x58 7x53 m1_on_gp42.67330YesNoYesNo99
975x54 6x44 m1_on_gp38.62261.67736NoNoYesYes99
983x47 5x54 m1_on_gp38.79881.04496NoNoNoNo99
99b.l11x2 b.l9x3 m1_on_gp17.78170YesNoNoNo99
1003x48 5x57 Shared15.214140.6902NoNoNoNo78
1013x48 3x52 Shared14.55439.308NoNoNoYes77
1023x52 I2x53 Shared14.422478.9201NoYesNoYes79
103I2x53 I2x57 Shared13.407845.5777NoYesYesYes98
1047x42 Lig Shared19.857381.6063YesYesYesYes80
1053x43 6x44 Shared37.722115.9244YesNoYesYes89
1066x48 Lig Shared32.296868.0941YesYesYesYes80
1076x44 6x48 Shared38.805915.4245YesYesYesYes98
1082x60 3x28 Shared17.339532.195YesYesYesYes77
1092x60 7x38 Shared13.280128.9126YesYesYesYes77
1107x38 Lig Shared17.281925.2055YesYesYesYes70
1112x60 7x42 Shared13.239133.249YesYesYesYes78
1123x28 E1x50 Shared13.261726.9582YesYesYesYes79
1133x33 Lig Shared13.166215.313YesYesYesYes80
1143x37 Lig m1_off8.407548.6765YesYesYesYes80
1156x51 Lig m1_off1.0205116.6772YesNoYesYes80
1166x52 Lig m1_off012.6901NoNoYesYes80
1172x64 NT.K20 m1_off028.9999NoNoNoYes70
1182x60 2x64 m1_off8.160132.2733YesYesNoNo77
1191x32 NT.K20 m1_off022.5193NoNoNoYes40
1201x32 2x65 m1_off013.9639NoNoNoNo46
1212x61 2x65 m1_off0.51327310.5068NoNoNoNo86
1222x57 7x42 m1_off0.55179216.4995NoYesYesYes88
1232x53 7x42 m1_off059.0538YesYesYesYes88
1241x50 2x50 m1_off2.0226543.8763YesYesYesYes99
1252x50 7x46 m1_off1.9975651.0856YesYesNoNo99
1262x53 7x46 m1_off1.7515152.0914YesYesNoNo89
1271x50 2x47 m1_off039.6242YesYesNoNo99
1281x60 I1x50 m1_off7.1509816.1261YesYesNoNo89
1298x50 I1x50 m1_off7.2919617.2403YesYesNoNo99
1301x56 8x50 m1_off1.0004325.4434NoNoYesYes99
1311x56 8x54 m1_off026.5938NoNoNoYes99
1321x53 8x54 m1_off1.4497232.0264NoNoNoYes99
1331x53 2x47 m1_off1.738738.5461NoNoNoNo99
1341x57 2x41 m1_off2.6036618.5834NoNoNoNo87
1352x41 4x39 m1_off021.7033NoNoNoNo75
1362x38 4x39 m1_off0.87079831.0236YesNoNoNo75
1372x38 I2x57 m1_off3.895636.9049YesNoYesYes78
1385x53 5x57 m1_off093.8597NoNoNoNo78
1393x44 5x53 m1_off0.14150895.0914NoNoNoNo77
1403x44 5x50 m1_off0.28297696.3231NoNoNoNo79
1413x40 5x50 m1_off0100NoNoNoNo99
1423x37 3x40 m1_off053.8411YesYesNoNo89
1433x51 3x52 m1_off042.3736NoYesNoYes87
1443x51 5x57 m1_off0.70729652.0975NoYesNoNo88
1453x40 6x48 m1_off0.00097929648.8632NoNoYesYes98
1462x42 3x49 m1_off0.75589415.6895YesYesNoNo89
1473x49 I2x53 m1_off0.88377418.5503NoNoNoYes99
1482x63 E1x50 m1_off0.0038763818.8755YesNoYesYes79
1492x63 E2.Q177 m1_off2.0422817.1891YesNoNoNo74
150E2.V173 E2x51 m1_off1.0211210.3834NoNoNoNo44
151E2.L174 E2x51 m1_off012.0938NoNoNoNo34
152E2.L174 E2.Q177 m1_off1.0211613.7983NoNoNoNo34
1533x33 E2x52 m1_off9.810314.256YesYesYesYes87
1543x30 4x61 m1_off5.0074220.571NoNoYesYes87
1553x33 4x61 m1_off2.9941610.6785YesYesYesYes87
1564x57 4x61 m1_off3.1013112.5124YesYesYesYes87
1573x30 4x58 m1_off012.7895NoNoNoNo86
1583x43 6x41 m1_off015.5509YesNoNoNo87
1596x37 6x41 m1_off014.8402NoNoNoNo97
1603x50 6x37 m1_off014.0964YesYesNoNo99
1613x50 5x61 m1_off010.7116YesYesNoNo99
162E2.F182 E2x52 m1_off8.8650315.0059YesYesYesYes67
1635x43 Lig m1_off010.022NoNoYesYes80
1644x64 E2.F182 m1_off5.2175716.62YesNoYesYes76
1656x51 7x34 m1_off022.3899YesNoYesYes87
1666x58 7x34 m1_off0.51294711.3079NoNoYesYes57
1675x37 6x58 m1_off010.0521NoNoNoNo55
1685x48 6x52 m1_off0.017953812.8617YesNoNoNo78
1695x45 5x48 m1_off1.536811.2747NoNoYesNo67
1706x47 6x48 m1_off0.51751711.8891NoYesYesYes88

Here, those paths that begin and end at given residue pair(s) or that pass through a residue are used to generate a novel metapath. Such a path filtering is particularly recommended if some information on allosteric residues is available. The selection syntax for a residue pair ("Pairs") is C:C:c534,A:A:?600 (the lower-case "c" stands for cytosine and "?" indicates any non standard amino acid or nucleotide residue). Selection of more than one apical residue pair has the following syntax: C:C:c534,A:A:?600,C:C:c534,A:A:E41. Only one residue can be selected as a tail ("Tail"). For midway residue(s), each residue must be separated by a comma as well e.g. A:A:?600,A:A:E41.

Midway



Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.


2D representation of the interactions of this orthosteric/allosteric ligand.


Node1Node2OwnerNet1LinkStrengthNet2LinkStrengthComm1Comm2Node1ShellNode2Shell
3x32LigShared4.339.681110
3x33LigShared20.9613.381110
3x36LigShared9.5911.781110
3x37LigShared5.110.441110
4x57LigShared87.311110
5x43Ligm1_off4.7100010
5x461LigShared4.023.371110
6x48LigShared10.9116.251110
6x51LigShared14.228.361110
6x52Ligm1_off10.5200110
7x38LigShared16.4710.031110
7x41LigShared6.084.531110
7x42LigShared4.495.851110
2x532x56Shared7.743.11022
2x537x42m1_off4.8401021
2x563x32Shared11.7810.311121
2x567x42Shared3.823.821121
2x577x42Shared13.1711.970121
2x607x38Shared19.8611.911121
2x607x42Shared7.946.951121
3x327x38m1_off4.601111
3x327x42Shared10.349.21111
3x334x57Shared15.4316.41111
3x334x61Shared3.633.631112
3x33E2x52Shared8.467.251112
3x337x38Shared4.966.951111
3x366x48Shared6.183.711111
3x373x40m1_off4.301111
3x374x53Shared5.785.781112
3x374x57Shared8.768.761111
3x375x461Shared4.554.551111
3x405x50m1_off3.5300112
3x406x48Shared3.684.90111
4x574x61Shared3.523.521112
4x61E2x52Shared5.895.891122
E2.L183E2x52Shared7.147.141022
5x43E2.L183m1_off4.4200012
5x475x51Shared7.877.871112
5x476x44m1_off5.3601112
5x476x48Shared7.026.011111
5x476x52Shared22.9625.371111
5x486x52Shared5.813.490121
6x446x48Shared17.048.021121
6x447x45m1_off3.6201122
6x476x48Shared3.643.641121
6x477x45Shared5.857.311122
6x487x41Shared11.7516.981111
6x487x45Shared7.9110.171112
6x517x34m1_off6.7501112
6x517x38Shared7.943.971111
7x387x42m1_off6.9501111
4x564x57m1_off3.4200021
3x414x53m1_off3.0700022
5x44Ligm1_off2.0100010
2x533x36m1_on_gp04.641021
2x577x39m1_on_gp08.140122
2x607x39m1_on_gp04.821122
3x336x51m1_on_gp07.941111
3x373x41m1_on_gp05.441112
3x406x44m1_on_gp03.930112
3x40Ligm1_on_gp05.310110
4x575x43m1_on_gp04.851111
5x475x48m1_on_gp011.351112
5x476x49m1_on_gp03.891112
5x47Ligm1_on_gp05.211110
5x516x44m1_on_gp03.930022
6x516x52m1_on_gp08.141111
6x516x55m1_on_gp06.311112
7x397x42m1_on_gp018.330121
7x347x38m1_on_gp02.891021
3x374x56m1_on_gp02.661112
5x445x48m1_on_gp01.330012

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Difference Members
Id Description
m1_on_gp 6OIJ-M1-Iperoxo-chim(NtGi1L-G11)/β1/γ2
m1_off 5CXV-M1-Tiotropium
Network Difference
Value m1_on_gp m1_off
Imin 3.01 3.5
Number of Linked Nodes 861 261
Number of Specific Nodes 622 (72.24%) 22  (8.43%)
Number of Shared Nodes 239 (27.76%) 239  (91.57%)
Number of Links 1021 299
Number of Specific Links 850 (83.25%) 128  (42.81%)
Number of Shared Links 171 (16.75%) 171  (57.19%)
Number of Hubs 156 40
Number of Specific Hubs 129 (82.69%) 13  (32.50%)
Number of Shared Hubs 27 (17.31%) 27  (67.50%)
Average % Shared Neighbours (Jaccard) 12.45
Average % Shared Neighbours (Otsuka) 15.04
Average % Shared Neighbours (Overlap Coefficient) 17.52
Average % Shared Cliques (k3-6) 52.80
Graphlets Similarity 0.735361
Paths Difference
Value m1_on_gp m1_off
Number Of Nodes in MetaPath 108 69
Specific Nodes in MetaPath 91 (84.26%) 52  (75.36%)
Shared Nodes in MetaPath 239 (27.76%) 239  (27.76%)
Number Of Links MetaPath 113 71
Specific Links in MetaPath 99 (87.61%) 57  (80.28%)
Shared Links in MetaPath 171 (16.75%) 171  (16.75%)
Number of Shortest Paths 2872443 70747
Length Of Smallest Path 3 3
Average Path Length 46.0177 14.5152
Length of Longest Path 84 34
Minimum Path Strength 1.33 1.32
Average Path Strength 6.28084 6.3387
Maximum Path Strength 25.18 18.1467
Minimum Path Correlation 0.7 0.7
Average Path Correlation 0.98595 0.923326
Maximum Path Correlation 1 0.99
Minimum % Of Corr. Nodes 1.81818 4.16667
Average % Of Corr. Nodes 26.5782 45.2905
Maximum % Of Corr. Nodes 100 100
Minimum Path Hubs % 0 0
Average Path Hubs % 48.916 44.888
Maximum Path Hubs % 100 100

Details about the values in these tables can be found in the corresponding documentation page .

You can download a compressed (zip) file with structure(s), 3D outputs (as PyMol and VMD scripts) and numerical data files (as csv and plain text files).

Download m1_off_on_gp.zip<



You can click to copy the link of this page to easily come back here later

or use this QR code to link and share this page.



You can also  read or  download a guide explaining the meaning of all files and numerical data.