psnGPCR

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Orange: nodes, hubs and links specific of m4_on_allo network

Green: nodes, hubs and links shared by both networks

Purple: nodes, hubs and links specific of m4_on network

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Owner: the name of the network the link belong to or "Shared" if the corresponding link is present in both networks.

Strength: the interaction strength between the two nodes or 0 if the link is not present.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Owner	m4_on_allo Int. Strength	m4_on Int. Strength	m4_on_allo Hub1?	m4_on Hub1?	m4_on_allo Hub2?	m4_on Hub2?	ConSurf1	ConSurf2
1	1x50	2x51	m4_on_allo	100	0	No	No	Yes	No	9	9
2	1x58	2x44	m4_on_allo	100	0	No	No	Yes	No	5	8
3	2x42	4x46	m4_on_allo	100	0	Yes	No	No	No	8	9
4	2x59	E1x50	m4_on_allo	100	0	No	No	Yes	Yes	7	9
5	2x60	7x35	m4_on_allo	100	0	Yes	Yes	No	No	8	6
6	2x60	7x39	m4_on_allo	100	0	Yes	Yes	No	No	8	9
7	2x60	Allo1	m4_on_allo	100	0	Yes	Yes	Yes	No	8	0
8	2x63	Allo1	m4_on_allo	100	0	No	No	Yes	No	8	0
9	E1x49	E1x51	m4_on_allo	100	0	No	No	No	No	5	5
10	E1x49	E2.N183	m4_on_allo	100	0	No	No	No	No	5	4
11	3x33	4x61	m4_on_allo	100	0	Yes	Yes	No	No	9	8
12	3x53	I2x57	m4_on_allo	100	0	No	No	Yes	Yes	9	9
13	4x61	E2.F189	m4_on_allo	100	0	No	No	Yes	Yes	8	8
14	4x62	4x63	m4_on_allo	100	0	No	No	No	No	6	7
15	E2.P181	E2.V180	m4_on_allo	100	0	No	No	Yes	No	3	5
16	Allo1	E2x51	m4_on_allo	100	0	Yes	No	No	No	0	4
17	E2.S191	E3.Q427	m4_on_allo	100	0	No	No	No	No	7	3
18	5x40	6x59	m4_on_allo	100	0	No	No	No	No	8	7
19	5x48	6x52	m4_on_allo	100	0	Yes	Yes	No	No	8	9
20	6x52	Lig	m4_on_allo	100	0	No	No	Yes	Yes	9	0
21	6x54	7x34	m4_on_allo	100	0	No	No	Yes	No	7	6
22	Allo1	E3.Q427	m4_on_allo	100	0	Yes	No	No	No	0	3
23	7x33	E3.I430	m4_on_allo	100	0	No	No	No	Yes	5	6
24	7x31	Allo1	m4_on_allo	100	0	No	No	Yes	No	3	0
25	7x34	Allo1	m4_on_allo	100	0	Yes	No	Yes	No	6	0
26	7x38	Allo1	m4_on_allo	100	0	Yes	Yes	Yes	No	7	0
27	7x39	7x42	m4_on_allo	100	0	No	No	Yes	Yes	9	9
28	7x52	7x53	m4_on_allo	100	0	No	No	Yes	Yes	9	9
29	1x57	8x50	m4_on_allo	33.3333	0	No	No	Yes	Yes	9	9
30	3x52	3x56	m4_on_allo	66.6667	0	No	No	No	No	7	7
31	2x65	2x66	m4_on_allo	33.3333	0	Yes	No	No	Yes	7	5
32	4x59	4x63	m4_on_allo	33.3333	0	No	No	No	No	9	7
33	I2x50	I2x51	m4_on_allo	0	0	No	No	No	No	9	7
34	3x41	4x49	m4_on_allo	33.3333	0	No	No	No	No	8	9
35	1x53	8x54	m4_on_allo	33.3333	0	No	No	Yes	Yes	9	9
36	1x34	1x37	m4_on_allo	33.3333	0	Yes	No	No	No	4	5
37	1x42	7x47	m4_on_allo	33.3333	0	No	No	Yes	No	6	8
38	2x50	3x39	m4_on_allo	33.3333	0	Yes	Yes	No	No	9	9
39	1x51	1x55	m4_on_allo	0	0	No	No	No	No	7	6
40	1x53	2x47	m4_on_allo	0	0	No	No	No	No	9	9
41	E2.K177	E2.T179	m4_on_allo	33.3333	0	No	No	No	No	3	5
42	8x56	8x60	m4_on_allo	33.3333	0	No	No	No	No	0	0
43	1x32	2x65	m4_on_allo	0	0	No	No	Yes	No	0	7
44	3x51	5x61	m4_on_allo	0	0	Yes	Yes	No	No	9	9
45	2x44	2x48	m4_on_allo	33.3333	0	Yes	No	No	No	8	8
46	6x60	6x61	m4_on_allo	33.3333	0	No	No	No	No	6	7
47	5x44	6x56	m4_on_allo	33.3333	0	No	No	No	No	8	7
48	5x62	5x63	m4_on_allo	0	0	No	No	No	No	8	4
49	7x32	Allo1	m4_on_allo	33.3333	0	No	No	Yes	No	4	0
50	4x42	4x43	m4_on_allo	0	0	No	No	No	No	8	5
51	I1x48	I1x49	m4_on_allo	33.3333	0	No	No	No	No	8	6
52	2x41	4x42	m4_on_allo	0	0	No	No	No	No	7	8
53	1x47	2x55	m4_on_allo	0	0	No	No	No	No	7	5
54	4x68	E2.T179	m4_on_allo	33.3333	0	No	No	No	No	5	5
55	6x47	7x48	m4_on_allo	0	0	No	No	No	No	9	7
56	1x58	1x59	m4_on_allo	33.3333	0	No	No	No	No	5	7
57	3x31	3x35	m4_on_allo	0	0	No	No	No	No	6	8
58	1x48	1x52	m4_on_allo	0	0	No	No	Yes	No	5	8
59	4x41	4x45	m4_on_allo	33.3333	0	No	No	No	No	8	8
60	4x44	4x45	m4_on_allo	0	0	No	No	No	No	3	8
61	1x52	8x57	m4_on_allo	0	0	Yes	No	No	No	8	0
62	1x48	1x49	m4_on_allo	0	0	No	No	No	No	5	9
63	7x43	7x47	m4_on_allo	0	0	No	No	Yes	No	6	8
64	1x35	1x39	m4_on_allo	0	0	No	No	No	No	7	7
65	1x43	1x44	m4_on_allo	0	0	Yes	No	No	No	8	5
66	3x23	3x27	m4_on_allo	0	0	No	No	No	No	5	7
67	1x52	8x58	m4_on_allo	0	0	Yes	No	No	No	8	0
68	6x35	6x39	m4_on_allo	0	0	Yes	No	No	No	7	9
69	1x34	1x35	m4_on_allo	0	0	Yes	No	No	No	4	7
70	6x61	E3.S428	m4_on_allo	0	0	No	No	No	No	7	3
71	8x48	8x51	m4_on_allo	0	0	No	No	No	No	5	9
72	1x33	2x65	m4_on_allo	0	0	No	No	Yes	No	6	7
73	4x52	4x55	m4_on_allo	0	0	No	No	No	No	6	5
74	8x52	8x56	m4_on_allo	0	0	No	No	No	No	6	0
75	1x31	1x34	m4_on_allo	0	0	No	Yes	Yes	No	0	4
76	6x35	6x38	m4_on_allo	0	0	Yes	No	No	No	7	8
77	1x39	2x61	Shared	100	100	No	No	No	No	7	8
78	1x39	7x39	Shared	100	100	No	No	No	No	7	9
79	1x43	2x57	Shared	100	25	Yes	No	Yes	Yes	8	9
80	1x46	2x57	Shared	100	100	No	No	Yes	Yes	8	9
81	1x46	7x47	Shared	100	100	No	No	Yes	No	8	8
82	1x50	2x50	Shared	100	100	No	No	Yes	Yes	9	9
83	1x50	7x50	Shared	100	100	No	No	No	No	9	9
84	1x52	8x54	Shared	100	100	Yes	No	Yes	Yes	8	9
85	1x54	2x44	Shared	100	100	No	Yes	Yes	No	8	8
86	1x54	2x51	Shared	100	50	No	Yes	Yes	No	8	9
87	1x56	8x53	Shared	100	100	No	No	No	Yes	9	9
88	1x56	8x54	Shared	100	25	No	No	Yes	Yes	9	9
89	1x57	2x44	Shared	100	100	No	No	Yes	No	9	8
90	1x60	I1x49	Shared	100	100	No	No	No	No	8	6
91	1x60	I1x50	Shared	100	100	No	No	No	Yes	8	9
92	1x60	8x53	Shared	100	100	No	No	No	Yes	8	9
93	8x49	I1x50	Shared	100	100	No	No	No	Yes	8	9
94	8x50	I1x50	Shared	100	100	Yes	Yes	No	Yes	9	9
95	2x37	2x40	Shared	100	100	No	No	No	Yes	8	9
96	2x38	I2x57	Shared	100	100	No	No	Yes	Yes	8	9
97	2x39	3x49	Shared	100	100	No	No	Yes	Yes	9	9
98	2x39	I2x57	Shared	100	100	No	No	Yes	Yes	9	9
99	2x40	8x50	Shared	100	100	No	Yes	Yes	Yes	9	9
100	2x41	4x39	Shared	100	25	No	No	No	No	7	6
101	2x42	3x45	Shared	100	100	Yes	No	No	No	8	8
102	2x42	3x49	Shared	100	100	Yes	No	Yes	Yes	8	9
103	2x42	4x42	Shared	100	50	Yes	No	No	No	8	8
104	2x45	3x42	Shared	100	100	No	No	No	No	9	9
105	2x45	4x46	Shared	100	100	No	No	No	No	9	9
106	2x45	4x50	Shared	100	100	No	No	No	No	9	9
107	2x46	3x42	Shared	100	100	No	Yes	No	No	9	9
108	2x46	3x43	Shared	100	100	No	Yes	No	No	9	9
109	2x46	7x49	Shared	100	100	No	Yes	No	No	9	9
110	2x50	7x46	Shared	100	100	Yes	Yes	No	No	9	9
111	2x50	7x49	Shared	100	100	Yes	Yes	No	No	9	9
112	2x52	3x35	Shared	100	100	No	No	No	No	8	8
113	2x53	2x56	Shared	100	100	No	No	No	No	9	9
114	2x53	3x35	Shared	100	100	No	No	No	No	9	8
115	2x53	7x46	Shared	100	100	No	No	No	No	9	9
116	2x54	2x57	Shared	100	100	No	No	Yes	Yes	9	9
117	2x55	2x551	Shared	100	50	No	No	No	No	5	6
118	2x56	3x32	Shared	100	100	No	No	No	Yes	9	9
119	2x56	7x42	Shared	100	100	No	No	Yes	Yes	9	9
120	2x57	7x42	Shared	100	100	Yes	Yes	Yes	Yes	9	9
121	2x59	3x28	Shared	100	100	No	No	No	Yes	7	7
122	2x60	2x64	Shared	100	100	Yes	Yes	No	No	8	7
123	2x60	7x38	Shared	100	100	Yes	Yes	Yes	Yes	8	7
124	2x62	2x66	Shared	100	25	No	No	No	Yes	8	5
125	2x63	E1x50	Shared	100	100	No	No	Yes	Yes	8	9
126	2x63	E2.Q184	Shared	100	100	No	No	No	No	8	5
127	2x66	E1x51	Shared	100	100	No	Yes	No	No	5	5
128	E1x50	E1x52	Shared	100	100	Yes	Yes	No	No	9	7
129	3x25	E1x50	Shared	100	100	No	No	Yes	Yes	9	9
130	3x28	E1x50	Shared	100	100	No	Yes	Yes	Yes	7	9
131	E1x50	E2x50	Shared	100	100	Yes	Yes	No	No	9	9
132	3x22	E2.R178	Shared	100	100	No	No	Yes	Yes	4	5
133	3x25	E2x50	Shared	100	100	No	No	No	No	9	9
134	3x26	E2.R178	Shared	100	100	No	No	Yes	Yes	8	5
135	3x32	7x42	Shared	100	100	No	Yes	Yes	Yes	9	9
136	3x32	Lig	Shared	100	100	No	Yes	Yes	Yes	9	0
137	3x33	4x57	Shared	100	100	Yes	Yes	Yes	Yes	9	8
138	3x33	E2x52	Shared	100	100	Yes	Yes	Yes	Yes	9	7
139	3x33	6x51	Shared	100	100	Yes	Yes	Yes	Yes	9	9
140	3x33	Lig	Shared	100	100	Yes	Yes	Yes	Yes	9	0
141	3x36	Lig	Shared	100	100	No	No	Yes	Yes	8	0
142	3x37	4x53	Shared	100	100	Yes	Yes	No	No	9	9
143	3x37	4x57	Shared	100	100	Yes	Yes	Yes	Yes	9	8
144	3x37	Lig	Shared	100	100	Yes	Yes	Yes	Yes	9	0
145	3x38	4x50	Shared	100	100	No	No	No	No	9	9
146	3x40	6x44	Shared	100	100	No	No	Yes	Yes	9	9
147	3x43	7x53	Shared	100	100	No	No	Yes	Yes	9	9
148	3x44	3x48	Shared	100	100	No	No	No	No	8	7
149	3x44	5x53	Shared	100	25	No	No	No	No	8	8
150	3x45	4x45	Shared	100	25	No	No	No	No	8	8
151	3x46	3x50	Shared	100	100	No	No	No	No	9	9
152	3x46	7x53	Shared	100	100	No	No	Yes	Yes	9	9
153	3x47	5x54	Shared	100	25	No	No	No	No	9	9
154	3x47	5x57	Shared	100	100	No	No	No	No	9	8
155	3x47	5x58	Shared	100	100	No	No	Yes	Yes	9	9
156	3x48	5x57	Shared	100	100	No	No	No	No	7	8
157	3x49	I2x53	Shared	100	100	Yes	Yes	Yes	Yes	9	9
158	3x49	I2x57	Shared	100	100	Yes	Yes	Yes	Yes	9	9
159	3x50	5x58	Shared	100	100	No	No	Yes	Yes	9	9
160	3x50	7x53	Shared	100	100	No	No	Yes	Yes	9	9
161	3x51	3x55	Shared	100	100	Yes	Yes	No	No	9	9
162	3x51	5x57	Shared	100	100	Yes	Yes	No	No	9	8
163	3x51	5x60	Shared	100	100	Yes	Yes	No	No	9	7
164	3x52	I2x53	Shared	100	100	No	No	Yes	Yes	7	9
165	I2x53	I2x57	Shared	100	100	Yes	Yes	Yes	Yes	9	9
166	4x54	4x58	Shared	100	100	No	No	No	No	7	7
167	4x56	4x57	Shared	100	100	No	No	Yes	Yes	8	8
168	4x57	5x43	Shared	100	100	Yes	Yes	No	No	8	9
169	4x57	Lig	Shared	100	100	Yes	Yes	Yes	Yes	8	0
170	4x61	E2x52	Shared	100	50	No	No	Yes	Yes	8	7
171	4x64	E2.Q188	Shared	100	100	No	Yes	Yes	Yes	7	8
172	4x64	E2.F189	Shared	100	100	No	Yes	Yes	Yes	7	8
173	4x65	4x66	Shared	100	100	No	No	No	No	7	6
174	4x65	E2.R178	Shared	100	100	No	No	Yes	Yes	7	5
175	4x65	E2.Q188	Shared	100	100	No	No	Yes	Yes	7	8
176	E2.R178	E2.V180	Shared	100	100	Yes	Yes	Yes	No	5	5
177	E2.Q188	E2.T179	Shared	100	100	Yes	Yes	No	No	8	5
178	E2.V180	E2x51	Shared	100	100	Yes	No	No	No	5	4
179	E2.Q188	E2.V180	Shared	100	100	Yes	Yes	Yes	No	8	5
180	E2.N183	E2.Q184	Shared	100	100	No	No	No	No	4	5
181	E2.F189	E2x52	Shared	100	100	Yes	Yes	Yes	Yes	8	7
182	5x36	5x37	Shared	100	100	No	Yes	No	No	7	5
183	5x36	5x39	Shared	100	100	No	Yes	No	No	7	8
184	5x37	6x59	Shared	100	100	No	No	No	No	5	7
185	5x41	6x56	Shared	100	100	No	No	No	No	7	7
186	5x45	5x48	Shared	100	100	No	No	Yes	Yes	7	8
187	5x461	Lig	Shared	100	50	No	No	Yes	Yes	9	0
188	5x47	5x48	Shared	100	100	Yes	Yes	Yes	Yes	9	8
189	5x47	5x51	Shared	100	100	Yes	Yes	No	No	9	8
190	5x47	6x44	Shared	100	100	Yes	Yes	Yes	Yes	9	9
191	5x47	6x49	Shared	100	100	Yes	Yes	No	No	9	7
192	5x47	6x52	Shared	100	100	Yes	Yes	No	No	9	9
193	5x51	6x44	Shared	100	100	No	No	Yes	Yes	8	9
194	5x58	6x37	Shared	100	100	Yes	Yes	No	No	9	9
195	5x58	6x40	Shared	100	100	Yes	Yes	No	Yes	9	9
196	5x58	6x41	Shared	100	100	Yes	Yes	No	No	9	8
197	5x65	6x30	Shared	100	0	No	No	No	Yes	9	9
198	5x66	5x68	Shared	100	50	No	No	No	No	7	8
199	5x66	6x30	Shared	100	100	No	No	No	Yes	7	9
200	6x40	7x53	Shared	100	100	No	Yes	Yes	Yes	9	9
201	6x42	6x46	Shared	100	25	No	No	No	No	8	5
202	6x44	6x48	Shared	100	100	Yes	Yes	Yes	Yes	9	9
203	6x45	6x49	Shared	100	100	No	No	No	No	8	7
204	6x47	7x45	Shared	100	100	No	No	No	Yes	9	9
205	6x48	7x41	Shared	100	100	Yes	Yes	No	No	9	9
206	6x48	7x45	Shared	100	100	Yes	Yes	No	Yes	9	9
207	6x48	Lig	Shared	100	100	Yes	Yes	Yes	Yes	9	0
208	6x50	7x40	Shared	100	25	No	No	No	No	9	9
209	6x51	6x55	Shared	100	100	Yes	Yes	No	No	9	8
210	6x51	7x38	Shared	100	100	Yes	Yes	Yes	Yes	9	7
211	6x51	7x41	Shared	100	100	Yes	Yes	No	No	9	9
212	6x51	Lig	Shared	100	100	Yes	Yes	Yes	Yes	9	0
213	6x58	7x34	Shared	100	100	No	No	Yes	No	5	6
214	6x61	E3.C429	Shared	100	100	No	No	No	No	7	7
215	7x34	E3.I430	Shared	100	100	Yes	No	No	Yes	6	6
216	7x30	7x33	Shared	100	100	No	No	No	No	6	5
217	7x38	Lig	Shared	100	100	Yes	Yes	Yes	Yes	7	0
218	7x41	Lig	Shared	100	100	No	No	Yes	Yes	9	0
219	7x45	7x49	Shared	100	100	No	Yes	No	No	9	9
220	7x54	8x50	Shared	100	100	No	No	Yes	Yes	9	9
221	8x47	8x49	Shared	100	100	No	No	No	No	9	8
222	8x47	8x50	Shared	100	100	No	No	Yes	Yes	9	9
223	6x36	7x56	Shared	33.3333	25	No	No	No	No	9	8
224	5x39	E2.F189	Shared	66.6667	100	No	No	Yes	Yes	8	8
225	5x48	6x56	Shared	66.6667	100	Yes	Yes	No	No	8	7
226	E2.L190	E2x52	Shared	66.6667	100	No	No	Yes	Yes	5	7
227	3x28	3x29	Shared	33.3333	100	No	Yes	No	No	7	8
228	3x37	3x41	Shared	66.6667	100	Yes	Yes	No	No	9	8
229	3x54	5x61	Shared	33.3333	100	No	No	No	No	9	9
230	3x56	I2x52	Shared	66.6667	25	No	No	No	No	7	7
231	3x34	4x54	Shared	33.3333	100	No	No	No	No	8	7
232	1x34	1x38	Shared	66.6667	100	Yes	No	No	No	4	5
233	5x55	6x41	Shared	33.3333	25	No	No	No	No	7	8
234	3x41	4x52	Shared	33.3333	0	No	No	No	No	8	6
235	3x44	5x50	Shared	33.3333	50	No	No	No	No	8	9
236	5x49	5x50	Shared	0	100	No	No	No	No	8	9
237	I2x53	I2x54	Shared	33.3333	100	Yes	Yes	No	No	9	7
238	5x56	5x60	Shared	33.3333	25	No	No	No	No	5	7
239	2x43	7x53	Shared	0	75	No	No	Yes	Yes	8	9
240	6x59	6x60	Shared	66.6667	100	No	No	No	No	7	6
241	4x38	4x40	Shared	0	100	No	No	No	No	9	6
242	1x43	2x58	Shared	33.3333	100	Yes	No	No	No	8	9
243	8x52	8x55	Shared	66.6667	100	No	No	No	No	6	0
244	1x51	2x51	Shared	0	100	No	No	Yes	No	7	9
245	5x63	5x66	Shared	33.3333	25	No	No	No	No	4	7
246	4x60	E2.F189	Shared	33.3333	25	No	No	Yes	Yes	8	8
247	5x65	6x33	Shared	0	100	No	No	No	No	9	9
248	5x62	6x34	Shared	33.3333	100	No	No	No	No	8	9
249	5x36	5x38	Shared	33.3333	25	No	Yes	No	No	7	5
250	2x49	4x50	Shared	0	0	No	No	No	No	9	9
251	6x57	E3.I430	Shared	0	0	No	No	No	Yes	7	6
252	1x47	2x51	Shared	0	0	No	No	Yes	No	7	9
253	3x24	E1x52	Shared	0	100	No	No	No	No	6	7
254	1x40	1x43	Shared	33.3333	25	No	No	Yes	No	6	8
255	5x58	5x61	Shared	0	100	Yes	Yes	No	No	9	9
256	6x49	6x50	Shared	0	50	No	No	No	No	7	9
257	6x54	7x37	Shared	0	0	No	No	No	No	7	7
258	1x36	2x65	Shared	0	0	No	No	Yes	No	6	7
259	6x34	6x38	Shared	33.3333	25	No	No	No	No	9	8
260	3x34	4x53	Shared	0	0	No	No	No	No	8	9
261	4x63	4x66	Shared	0	25	No	No	No	No	7	6
262	3x30	4x62	Shared	0	75	No	No	No	No	8	6
263	6x38	6x42	Shared	0	0	No	No	No	No	8	8
264	4x38	4x41	Shared	0	0	No	No	No	No	9	8
265	5x41	5x42	Shared	33.3333	0	No	No	No	No	7	7
266	3x21	3x24	Shared	0	0	No	No	No	No	8	6
267	5x67	6x29	Shared	0	25	No	No	No	No	6	7
268	3x54	5x64	Shared	0	0	No	No	No	No	9	8
269	3x56	I2x50	Shared	0	0	No	No	No	No	7	9
270	1x38	1x41	Shared	0	0	No	No	No	No	5	5
271	I1x48	I1x51	Shared	0	100	No	No	No	No	8	8
272	7x35	7x36	Shared	0	0	No	No	No	No	6	5
273	6x31	6x35	Shared	33.3333	25	No	No	Yes	No	7	7
274	5x48	6x53	Shared	0	0	Yes	Yes	No	No	8	7
275	7x55	8x54	Shared	0	100	No	No	Yes	Yes	8	9
276	8x55	8x58	Shared	0	25	No	No	No	No	0	0
277	5x67	5x69	Shared	0	0	No	No	No	No	6	6
278	6x43	7x48	Shared	0	0	No	No	No	No	8	7
279	5x51	5x52	Shared	0	0	No	No	No	No	8	5
280	1x45	7x47	Shared	0	0	No	No	Yes	No	5	8
281	6x47	7x43	Shared	0	25	No	No	No	No	9	6
282	7x51	7x55	Shared	0	0	No	No	No	No	7	8
283	4x56	5x46	Shared	0	0	No	No	No	No	8	7
284	5x62	6x37	Shared	0	0	No	No	No	No	8	9
285	3x22	E2.D182	Shared	0	25	No	No	No	No	4	3
286	5x55	5x59	Shared	0	0	No	No	No	No	7	4
287	6x27	6x30	Shared	0	25	No	No	No	Yes	5	9
288	6x28	6x31	Shared	0	25	No	No	No	No	6	7
289	6x32	6x35	Shared	0	25	No	No	Yes	No	9	7
290	4x68	4x69	Shared	0	0	No	No	No	No	5	4
291	8x48	8x52	Shared	0	0	No	No	No	No	5	6
292	4x51	4x55	Shared	0	0	No	No	No	No	5	5
293	1x29	1x32	Shared	0	0	No	No	No	No	0	0
294	1x30	1x31	Shared	0	25	No	No	No	Yes	0	0
295	3x27	4x62	Shared	0	25	No	No	No	No	7	6
296	I2x52	I2x56	Shared	0	25	No	No	No	No	7	6
297	6x29	6x32	Shared	0	25	No	No	No	No	7	9
298	1x57	2x40	m4_on	0	100	No	No	No	Yes	9	9
299	2x40	I1x50	m4_on	0	100	No	Yes	No	Yes	9	9
300	2x46	2x50	m4_on	0	100	No	Yes	Yes	Yes	9	9
301	2x57	7x39	m4_on	0	100	Yes	Yes	No	No	9	9
302	2x60	2x63	m4_on	0	100	Yes	Yes	No	No	8	8
303	2x60	3x28	m4_on	0	100	Yes	Yes	No	Yes	8	7
304	2x66	E1x49	m4_on	0	100	No	Yes	No	No	5	5
305	E1x50	E1x51	m4_on	0	100	Yes	Yes	No	No	9	5
306	3x29	E2x52	m4_on	0	100	No	No	Yes	Yes	8	7
307	3x33	7x38	m4_on	0	100	Yes	Yes	Yes	Yes	9	7
308	3x40	6x48	m4_on	0	100	No	No	Yes	Yes	9	9
309	3x51	3x52	m4_on	0	100	Yes	Yes	No	No	9	7
310	3x53	I2x53	m4_on	0	100	No	No	Yes	Yes	9	9
311	4x64	4x68	m4_on	0	100	No	Yes	No	No	7	5
312	4x64	5x39	m4_on	0	100	No	Yes	No	No	7	8
313	E2.P181	E2.Q184	m4_on	0	100	No	No	No	No	3	5
314	5x40	E2.L190	m4_on	0	100	No	No	No	No	8	5
315	5x47	6x48	m4_on	0	100	Yes	Yes	Yes	Yes	9	9
316	6x44	7x45	m4_on	0	100	Yes	Yes	No	Yes	9	9
317	6x48	6x52	m4_on	0	100	Yes	Yes	No	No	9	9
318	6x51	6x52	m4_on	0	100	Yes	Yes	No	No	9	9
319	6x54	E3.I430	m4_on	0	100	No	No	No	Yes	7	6
320	6x58	E3.Q427	m4_on	0	100	No	No	No	No	5	3
321	7x38	7x42	m4_on	0	100	Yes	Yes	Yes	Yes	7	9
322	3x28	3x32	m4_on	0	100	No	Yes	No	Yes	7	9
323	E2x51	Lig	m4_on	0	100	No	No	Yes	Yes	4	0
324	7x34	Lig	m4_on	0	100	Yes	No	Yes	Yes	6	0
325	4x41	4x44	m4_on	0	50	No	No	No	No	8	3
326	7x30	E3.I430	m4_on	0	25	No	No	No	Yes	6	6
327	6x40	7x52	m4_on	0	25	No	Yes	No	No	9	9
328	1x54	2x48	m4_on	0	0	No	Yes	No	No	8	8
329	1x42	7x39	m4_on	0	50	No	No	No	No	6	9
330	2x64	7x35	m4_on	0	50	No	No	No	No	7	6
331	1x53	7x50	m4_on	0	25	No	No	No	No	9	9
332	2x40	2x43	m4_on	0	75	No	Yes	No	No	9	8
333	1x54	2x47	m4_on	0	0	No	Yes	No	No	8	9
334	3x26	4x62	m4_on	0	25	No	No	No	No	8	6
335	2x46	3x39	m4_on	0	0	No	Yes	No	No	9	9
336	1x55	1x59	m4_on	0	25	No	No	No	No	6	7
337	7x31	Lig	m4_on	0	25	No	No	Yes	Yes	3	0
338	4x58	4x59	m4_on	0	25	No	No	No	No	7	9
339	6x32	6x36	m4_on	0	25	No	No	No	No	9	9
340	3x55	3x56	m4_on	0	25	No	No	No	No	9	7
341	8x54	8x55	m4_on	0	25	Yes	Yes	No	No	9	0
342	7x55	8x51	m4_on	0	0	No	No	No	No	8	9
343	3x45	4x49	m4_on	0	0	No	No	No	No	8	9
344	5x44	5x48	m4_on	0	0	No	No	Yes	Yes	8	8
345	2x38	4x39	m4_on	0	0	No	No	No	No	8	6
346	4x68	E2.K177	m4_on	0	25	No	No	No	No	5	3
347	1x44	1x48	m4_on	0	0	No	No	No	No	5	5
348	4x41	I2x57	m4_on	0	25	No	No	Yes	Yes	8	9
349	I2x51	I2x52	m4_on	0	25	No	No	No	No	7	7
350	1x35	2x65	m4_on	0	25	No	No	Yes	No	7	7
351	6x30	6x34	m4_on	0	25	No	Yes	No	No	9	9
352	4x43	4x46	m4_on	0	0	No	No	No	No	5	9
353	8x53	8x56	m4_on	0	25	No	Yes	No	No	9	0
354	1x49	1x52	m4_on	0	25	No	No	Yes	No	9	8
355	6x57	6x61	m4_on	0	25	No	No	No	No	7	7
356	2x41	I1x51	m4_on	0	25	No	No	No	No	7	8
357	7x48	7x52	m4_on	0	25	No	No	No	No	7	9
358	1x47	1x48	m4_on	0	0	No	No	No	No	7	5
359	1x32	2x66	m4_on	0	25	No	No	No	Yes	0	5
360	2x52	3x31	m4_on	0	25	No	No	No	No	8	6
361	1x58	I1x51	m4_on	0	25	No	No	No	No	5	8
362	7x30	7x32	m4_on	0	25	No	No	No	No	6	4
363	4x63	4x67	m4_on	0	25	No	No	No	No	7	5
364	2x65	E1x51	m4_on	0	25	Yes	No	No	No	7	5
365	1x26	1x31	m4_on	0	25	No	No	No	Yes	0	0
366	1x33	1x37	m4_on	0	0	No	No	No	No	6	5
367	8x53	8x57	m4_on	0	25	No	Yes	No	No	9	0
368	1x29	1x31	m4_on	0	25	No	No	No	Yes	0	0
369	6x26	6x29	m4_on	0	25	No	No	No	No	0	7
370	2x551	3x31	m4_on	0	25	No	No	No	No	6	6
371	E3.S428	Lig	m4_on	0	0	No	No	Yes	Yes	3	0
372	6x36	6x40	m4_on	0	0	No	No	No	Yes	9	9
373	1x32	1x33	m4_on	0	0	No	No	No	No	0	6
374	1x41	1x42	m4_on	0	0	No	No	No	No	5	6
375	1x59	8x57	m4_on	0	0	No	No	No	No	7	0
376	2x66	2x67	m4_on	0	0	No	Yes	No	No	5	7
377	3x23	3x24	m4_on	0	0	No	No	No	No	5	6
378	5x36	E2.S191	m4_on	0	0	No	Yes	No	No	7	7
379	4x55	4x56	m4_on	0	0	No	No	No	No	5	8
380	I2x55	I2x56	m4_on	0	0	No	No	No	No	6	6
381	8x56	8x59	m4_on	0	0	No	No	No	No	0	0
382	1x27	1x31	m4_on	0	0	No	No	No	Yes	0	0

Orange: nodes, hubs and links specific of m4_on_allo network

Green: nodes, hubs and links shared by both networks

Purple: nodes, hubs and links specific of m4_on network

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Owner: the name of the network the hub belong to or "Shared" if the corresponding hub is present in both networks.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub in the corresponding network.

Num Of Links: the number of links of the corresponding hub in the corresponding network.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Owner	m4_on_allo Avg Int. Strength	m4_on Avg Int. Strength	m4_on_allo Num Of Links	m4_on Num Of Links	ConSurf
1	1x34	m4_on_allo	0	0	4	1	4
2	1x43	m4_on_allo	0	0	4	3	8
3	1x52	m4_on_allo	0	0	4	2	8
4	2x42	m4_on_allo	66.6667	50	4	3	8
5	2x44	m4_on_allo	33.3333	0	4	2	8
6	2x51	m4_on_allo	0	0	4	3	9
7	2x65	m4_on_allo	0	0	4	3	7
8	E2.V180	m4_on_allo	0	0	4	3	5
9	6x35	m4_on_allo	0	0	4	2	7
10	7x34	m4_on_allo	33.3333	25	4	3	6
11	7x47	m4_on_allo	0	0	4	2	8
12	Allo1	m4_on_allo	100	0	8	0	0
13	2x50	Shared	100	100	4	4	9
14	2x57	Shared	66.6667	50	4	5	9
15	2x60	Shared	100	75	5	4	8
16	E1x50	Shared	100	100	6	6	9
17	3x33	Shared	66.6667	75	5	5	9
18	3x37	Shared	66.6667	25	4	4	9
19	3x49	Shared	100	100	4	4	9
20	3x51	Shared	66.6667	50	4	4	9
21	I2x53	Shared	33.3333	100	4	5	9
22	I2x57	Shared	100	100	5	5	9
23	4x57	Shared	100	100	5	5	8
24	E2.R178	Shared	66.6667	25	4	4	5
25	E2x52	Shared	33.3333	100	4	5	7
26	E2.Q188	Shared	33.3333	25	4	4	8
27	E2.F189	Shared	66.6667	25	5	4	8
28	5x47	Shared	100	100	5	6	9
29	5x48	Shared	0	25	5	5	8
30	5x58	Shared	66.6667	75	6	6	9
31	6x44	Shared	100	100	4	5	9
32	6x48	Shared	100	100	4	7	9
33	6x51	Shared	66.6667	100	5	6	9
34	7x38	Shared	66.6667	75	4	5	7
35	7x42	Shared	100	100	4	4	9
36	7x53	Shared	66.6667	100	6	5	9
37	8x50	Shared	66.6667	100	5	4	9
38	8x54	Shared	0	25	4	4	9
39	Lig	Shared	100	100	11	14	0
40	1x54	m4_on	0	0	2	4	8
41	I1x50	m4_on	33.3333	50	3	4	9
42	2x40	m4_on	33.3333	50	2	5	9
43	2x46	m4_on	0	75	3	5	9
44	2x66	m4_on	0	0	3	5	5
45	3x28	m4_on	33.3333	50	3	5	7
46	3x32	m4_on	100	50	3	4	9
47	4x64	m4_on	33.3333	0	2	4	7
48	5x36	m4_on	0	0	3	4	7
49	6x30	m4_on	0	0	3	4	9
50	6x40	m4_on	0	0	2	4	9
51	E3.I430	m4_on	33.3333	0	3	4	6
52	7x45	m4_on	0	50	3	4	9
53	8x53	m4_on	0	0	2	4	9
54	1x31	m4_on	0	0	2	4	0

Orange: nodes, hubs and links specific of m4_on_allo network

Green: nodes, hubs and links shared by both networks

Purple: nodes, hubs and links specific of m4_on network

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Owner: the name of the network the link belong to or "Shared" if the corresponding link is present in both networks.

Recurrence: the relative Recurrence in the filtered pool of shortest paths.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Owner	m4_on_allo Recurrence	m4_on Recurrence	m4_on_allo Hub1?	m4_on Hub1?	m4_on_allo Hub2?	m4_on Hub2?	ConSurf1	ConSurf2
1	1x39	7x39	m4_on_allo	17.2201	2.18622	No	No	No	No	7	9
2	7x39	7x42	m4_on_allo	14.8273	0	No	No	Yes	Yes	9	9
3	2x56	7x42	m4_on_allo	10.4843	9.29212	No	No	Yes	Yes	9	9
4	1x50	2x50	m4_on_allo	43.0625	3.10189	No	No	Yes	Yes	9	9
5	1x50	2x51	m4_on_allo	41.3217	0	No	No	Yes	No	9	9
6	1x54	2x51	m4_on_allo	35.9355	5.17433	No	Yes	Yes	No	8	9
7	1x54	2x44	m4_on_allo	35.0196	8.25454	No	Yes	Yes	No	8	8
8	1x57	2x44	m4_on_allo	31.271	9.27045	No	No	Yes	No	9	8
9	1x57	8x50	m4_on_allo	30.3218	0	No	No	Yes	Yes	9	9
10	8x50	I1x50	m4_on_allo	24.5838	0.162544	Yes	Yes	No	Yes	9	9
11	1x52	8x54	m4_on_allo	11.3274	2.11037	Yes	No	Yes	Yes	8	9
12	2x60	7x39	m4_on_allo	12.3101	0	Yes	Yes	No	No	8	9
13	7x38	Lig	m4_on_allo	51.2177	9.47363	Yes	Yes	Yes	Yes	7	0
14	2x46	3x42	m4_on_allo	33.2757	7.29824	No	Yes	No	No	9	9
15	2x45	3x42	m4_on_allo	32.2385	6.2715	No	No	No	No	9	9
16	2x45	4x46	m4_on_allo	28.029	2.11037	No	No	No	No	9	9
17	2x42	4x46	m4_on_allo	26.9615	0	Yes	No	No	No	8	9
18	2x42	3x49	m4_on_allo	14.7879	7.47975	Yes	No	Yes	Yes	8	9
19	3x32	7x42	m4_on_allo	10.3388	4.31826	No	Yes	Yes	Yes	9	9
20	2x50	7x49	m4_on_allo	49.0553	1.58752	Yes	Yes	No	No	9	9
21	2x63	Allo1	m4_on_allo	22.1848	0	No	No	Yes	No	8	0
22	2x63	E1x50	m4_on_allo	10.0082	1.09988	No	No	Yes	Yes	8	9
23	2x63	E2.Q184	m4_on_allo	11.843	3.48387	No	No	No	No	8	5
24	E2.N183	E2.Q184	m4_on_allo	10.7512	1.1649	No	No	No	No	4	5
25	Allo1	E2x51	m4_on_allo	24.9507	0	Yes	No	No	No	0	4
26	E2.R178	E2.V180	m4_on_allo	10.4025	9.73099	Yes	Yes	Yes	No	5	5
27	3x37	Lig	m4_on_allo	10.915	7.64771	Yes	Yes	Yes	Yes	9	0
28	6x44	6x48	m4_on_allo	10.5329	1.23534	Yes	Yes	Yes	Yes	9	9
29	3x48	5x57	m4_on_allo	10.2175	7.84006	No	No	No	No	7	8
30	5x58	5x61	m4_on_allo	13.9508	4.55937	Yes	Yes	No	No	9	9
31	4x65	4x66	m4_on_allo	21.9058	5.75136	No	No	No	No	7	6
32	4x63	4x66	m4_on_allo	18.7396	3.83876	No	No	No	No	7	6
33	4x62	4x63	m4_on_allo	12.3889	0	No	No	No	No	6	7
34	E2.Q188	E2.V180	m4_on_allo	12.856	8.4496	Yes	Yes	Yes	No	8	5
35	4x65	E2.Q188	m4_on_allo	18.4909	4.40495	No	No	Yes	Yes	7	8
36	4x64	E2.Q188	m4_on_allo	20.5016	4.13946	No	Yes	Yes	Yes	7	8
37	3x33	4x61	m4_on_allo	23.2251	0	Yes	Yes	No	No	9	8
38	4x61	E2.F189	m4_on_allo	22.4305	0	No	No	Yes	Yes	8	8
39	5x39	E2.F189	m4_on_allo	23.2281	6.9569	No	No	Yes	Yes	8	8
40	5x36	5x39	m4_on_allo	20.9323	6.40154	No	Yes	No	No	7	8
41	5x36	5x37	m4_on_allo	16.3224	3.2238	No	Yes	No	No	7	5
42	5x37	6x59	m4_on_allo	14.0084	2.15371	No	No	No	No	5	7
43	6x52	Lig	m4_on_allo	12.3768	0	No	No	Yes	Yes	9	0
44	5x62	5x63	m4_on_allo	13.6839	0	No	No	No	No	8	4
45	5x63	5x66	m4_on_allo	11.6641	1.57939	No	No	No	No	4	7
46	6x34	6x38	m4_on_allo	21.7087	4.72733	No	No	No	No	9	8
47	1x34	1x35	m4_on_allo	11.6247	0	Yes	No	No	No	4	7
48	1x35	1x39	m4_on_allo	13.6293	0	No	No	No	No	7	7
49	6x35	6x38	m4_on_allo	15.7038	0	Yes	No	No	No	7	8
50	4x64	E2.F189	m4_on_allo	21.8118	4.78964	No	Yes	Yes	Yes	7	8
51	7x38	Allo1	m4_on_allo	45.6525	0	Yes	Yes	Yes	No	7	0
52	2x57	7x42	Shared	10.0992	17.1295	Yes	Yes	Yes	Yes	9	9
53	2x53	2x56	Shared	13.2775	25.7985	No	No	No	No	9	9
54	2x53	7x46	Shared	12.3313	25.7822	No	No	No	No	9	9
55	2x50	7x46	Shared	12.1463	25.8987	Yes	Yes	No	No	9	9
56	1x60	I1x50	Shared	22.6822	18.419	No	No	No	Yes	8	9
57	1x60	8x53	Shared	18.6425	16.4739	No	No	No	Yes	8	9
58	1x56	8x53	Shared	17.6235	11.2101	No	No	No	Yes	9	9
59	1x56	8x54	Shared	16.5863	10.1969	No	No	Yes	Yes	9	9
60	6x48	Lig	Shared	89.1335	64.1183	Yes	Yes	Yes	Yes	9	0
61	6x48	7x45	Shared	96.8489	66.8193	Yes	Yes	No	Yes	9	9
62	7x45	7x49	Shared	100	75.3312	No	Yes	No	No	9	9
63	2x46	7x49	Shared	99.2175	73.8277	No	Yes	No	No	9	9
64	3x32	Lig	Shared	14.0145	23.4064	No	Yes	Yes	Yes	9	0
65	2x46	3x43	Shared	81.0421	100	No	Yes	No	No	9	9
66	E2.V180	E2x51	Shared	24.1956	18.2564	Yes	No	No	No	5	4
67	3x33	Lig	Shared	41.5461	12.5999	Yes	Yes	Yes	Yes	9	0
68	3x43	7x53	Shared	80.299	99.8347	No	No	Yes	Yes	9	9
69	3x50	7x53	Shared	38.5801	41.4894	No	No	Yes	Yes	9	9
70	3x50	5x58	Shared	37.9492	41.2456	No	No	Yes	Yes	9	9
71	3x47	5x58	Shared	16.1253	59.2881	No	No	Yes	Yes	9	9
72	3x47	5x57	Shared	12.1402	56.5519	No	No	No	No	9	8
73	6x40	7x53	Shared	38.571	50.0312	No	Yes	Yes	Yes	9	9
74	5x58	6x40	Shared	37.8491	43.2368	Yes	Yes	No	Yes	9	9
75	3x33	E2x52	Shared	24.3351	14.9432	Yes	Yes	Yes	Yes	9	7
76	E2.F189	E2x52	Shared	22.5851	13.4343	Yes	Yes	Yes	Yes	8	7
77	5x58	6x37	Shared	40.609	19.657	Yes	Yes	No	No	9	9
78	5x62	6x37	Shared	38.8196	18.3079	No	No	No	No	8	9
79	5x62	6x34	Shared	23.6982	16.7881	No	No	No	No	8	9
80	2x46	2x50	m4_on	0	26.8767	No	Yes	Yes	Yes	9	9
81	2x43	7x53	m4_on	1.15852	34.4946	No	No	Yes	Yes	8	9
82	2x40	2x43	m4_on	0	33.6927	No	Yes	No	No	9	8
83	1x57	2x40	m4_on	0	10.2809	No	No	No	Yes	9	9
84	2x40	I1x50	m4_on	0	20.1067	No	Yes	No	Yes	9	9
85	3x51	5x57	m4_on	0.148606	48.1998	Yes	Yes	No	No	9	8
86	3x51	3x52	m4_on	0	33.8688	Yes	Yes	No	No	9	7
87	3x52	I2x53	m4_on	7.20286	32.4059	No	No	Yes	Yes	7	9
88	I2x53	I2x57	m4_on	0.0940163	17.8609	Yes	Yes	Yes	Yes	9	9
89	3x49	I2x53	m4_on	9.28335	10.1211	Yes	Yes	Yes	Yes	9	9
90	3x28	3x32	m4_on	0	32.6172	No	Yes	No	Yes	7	9
91	3x28	E1x50	m4_on	2.14721	30.6504	No	Yes	Yes	Yes	7	9
92	E1x50	E1x51	m4_on	0	21.5182	Yes	Yes	No	No	9	5
93	2x66	E1x51	m4_on	7.43942	16.2626	No	Yes	No	No	5	5
94	E2x51	Lig	m4_on	0	18.9527	No	No	Yes	Yes	4	0
95	3x51	3x55	m4_on	2.05319	10.9582	Yes	Yes	No	No	9	9
96	5x47	6x48	m4_on	0	11.7601	Yes	Yes	Yes	Yes	9	9
97	5x47	5x48	m4_on	3.74852	10.8851	Yes	Yes	Yes	Yes	9	8
98	6x30	6x34	m4_on	0	10.6439	No	Yes	No	No	9	9
99	7x34	Lig	m4_on	0	11.2264	Yes	No	Yes	Yes	6	0
100	1x32	2x66	m4_on	0	10.4841	No	No	No	Yes	0	5
101	2x56	3x32	m4_on	3.03885	16.5118	No	No	No	Yes	9	9

Here, those paths that begin and end at given residue pair(s) or that pass through a residue are used to generate a novel metapath. Such a path filtering is particularly recommended if some information on allosteric residues is available. The selection syntax for a residue pair ("Pairs") is C:C:c534,A:A:?600 (the lower-case "c" stands for cytosine and "?" indicates any non standard amino acid or nucleotide residue). Selection of more than one apical residue pair has the following syntax: C:C:c534,A:A:?600,C:C:c534,A:A:E41. Only one residue can be selected as a tail ("Tail"). For midway residue(s), each residue must be separated by a comma as well e.g. A:A:?600,A:A:E41.

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Node1	Node2	Owner	Net1LinkStrength	Net2LinkStrength	Comm1	Comm2	Node1Shell	Node2Shell
2x56	3x32	Shared	9.94	11.29	1	1	2	1
2x56	7x42	Shared	6.9975	5.93667	1	1	2	2
2x60	3x28	m4_on	5.305	0	0	1	2	2
2x60	7x38	Shared	17.6225	15.5533	0	1	2	1
3x32	7x42	Shared	10.915	9.96	1	1	1	2
3x32	Lig	Shared	4.765	7.42	1	1	1	0
3x33	4x57	Shared	13.8625	19.6133	1	1	1	1
3x33	E2x52	Shared	5.6525	6.85	1	1	1	2
3x33	6x51	Shared	6.4525	6.28667	1	1	1	1
3x33	7x38	m4_on	5.46	0	1	1	1	1
3x33	Lig	Shared	8.63	13.9367	1	1	1	0
3x36	Lig	Shared	6.8575	8.92667	0	0	1	0
3x37	3x41	Shared	5.6075	3.74	1	1	1	2
3x37	4x53	Shared	5.5875	4.96667	1	1	1	2
3x37	4x57	Shared	8.475	9.04	1	1	1	1
3x37	Lig	Shared	3.9725	7.18333	1	1	1	0
3x40	6x44	Shared	4.5875	4.80333	1	0	2	2
3x40	6x48	m4_on	4.29	0	1	0	2	1
4x56	4x57	Shared	5.9775	6.45333	0	0	2	1
4x57	5x43	Shared	8.185	9.3	1	1	1	2
4x57	Lig	Shared	11.645	4.6	1	1	1	0
E2.V180	E2x51	Shared	10.4875	5.68333	0	0	2	1
5x47	5x48	Shared	9.03	10.3167	1	1	2	2
5x47	6x44	Shared	4.825	5.00333	1	1	2	2
5x47	6x48	m4_on	6.015	0	1	1	2	1
5x47	6x52	Shared	17.2175	16.11	1	1	2	1
6x44	6x48	Shared	7.515	8.35333	1	1	2	1
6x44	7x45	m4_on	4.2275	0	1	1	2	2
6x48	6x52	m4_on	3.6725	0	1	1	1	1
6x48	7x41	Shared	8.1625	8.70667	1	1	1	1
6x48	7x45	Shared	9.04	14.3133	1	1	1	2
6x48	Lig	Shared	8.99	13	1	1	1	0
6x51	6x52	m4_on	5.2325	0	1	1	1	1
6x51	6x55	Shared	6.625	5.04667	1	1	1	2
6x51	7x38	Shared	6.455	4.96333	1	1	1	1
6x51	7x41	Shared	4.03	4.03	1	1	1	1
6x51	Lig	Shared	11.2	8.64333	1	1	1	0
6x54	E3.I430	m4_on	4.0075	0	0	0	2	2
6x58	7x34	Shared	4.8025	7.91	0	0	2	1
7x34	E3.I430	Shared	8.515	9.78667	0	0	1	2
7x38	7x42	m4_on	6.7	0	1	1	1	2
7x38	Lig	Shared	7.9225	5.57333	1	1	1	0
7x41	Lig	Shared	4.9125	6.04	1	1	1	0
3x28	3x32	m4_on	4.1875	0	0	2	2	1
E2x51	Lig	m4_on	7.925	0	0	0	1	0
7x34	Lig	m4_on	4.875	0	0	0	1	0
5x461	Lig	Shared	3.0025	4.87	0	0	1	0
4x61	E2x52	Shared	2.945	5.4	0	1	2	2
7x31	Lig	m4_on	2.5575	0	0	0	1	0
E3.S428	Lig	m4_on	0.7725	0	0	0	1	0
2x60	Allo1	m4_on_allo	0	5.05333	0	1	2	2
3x33	4x61	m4_on_allo	0	4.43333	1	1	1	2
Allo1	E2x51	m4_on_allo	0	31.98	0	1	2	1
5x48	6x52	m4_on_allo	0	5.42667	0	1	2	1
6x52	Lig	m4_on_allo	0	4.57333	1	1	1	0
6x54	7x34	m4_on_allo	0	5.04	0	0	2	1
7x31	Allo1	m4_on_allo	0	7.32667	0	0	1	2
7x34	Allo1	m4_on_allo	0	29.32	0	0	1	2
7x38	Allo1	m4_on_allo	0	5.56	1	1	1	2
6x61	E3.S428	m4_on_allo	0	0.573333	0	0	2	1

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Difference Members
	Id	Description
	m4_on_allo	7TRP-M₄-Iperoxo-LY2033298-Gi1/&β;1/&γ;2 7TRQ-M₄-Iperoxo-VU0467154-Gi1/&β;1/&γ;2 7V68-M₄-Iperoxo-PubChem 57664406-Gi1/&β;1/&γ;2
	m4_on	7TRS-M₄-Acetylcholine-Gi1/&β;1/&γ;2 7TRK-M₄-Iperoxo-Gi1/&β;1/&γ;2 8E9X-M₄-2-Deoxycytidine-chim(NtGi1-Go)/&β;1/&γ;2 7V6A-M₄-PubChem 9864275-Gi1/&β;1/&γ;2

Network Difference
Value	m4_on_allo	m4_on
I_min	3.99333	3.58
Number of Linked Nodes	273	277
Number of Specific Nodes	3 (1.10%)	7 (2.53%)
Number of Shared Nodes	270 (98.90%)	270 (97.47%)
Number of Links	297	306
Number of Specific Links	76 (25.59%)	85 (27.78%)
Number of Shared Links	221 (74.41%)	221 (72.22%)
Number of Hubs	39	42
Number of Specific Hubs	12 (30.77%)	15 (35.71%)
Number of Shared Hubs	27 (69.23%)	27 (64.29%)
Average % Shared Neighbours (Jaccard)	61.60
Average % Shared Neighbours (Otsuka)	69.49
Average % Shared Neighbours (Overlap Coefficient)	78.00
Average % Shared Cliques (k3-6)	61.54
Graphlets Similarity	0.611478

Paths Difference
Value	m4_on_allo	m4_on
Number Of Nodes in MetaPath	76	50
Specific Nodes in MetaPath	41 (53.95%)	15 (30.00%)
Shared Nodes in MetaPath	270 (98.90%)	270 (98.90%)
Number Of Links MetaPath	79	50
Specific Links in MetaPath	51 (64.56%)	22 (44.00%)
Shared Links in MetaPath	221 (74.41%)	221 (74.41%)
Number of Shortest Paths	65669	63257
Length Of Smallest Path	3	3
Average Path Length	14.9281	13.963
Length of Longest Path	33	29
Minimum Path Strength	0.486667	0.38625
Average Path Strength	6.57738	6.2759
Maximum Path Strength	30.65	15.1962
Minimum Path Correlation	0.7	0.7
Average Path Correlation	0.923324	0.915009
Maximum Path Correlation	0.99	0.99
Minimum % Of Corr. Nodes	3.22581	3.7037
Average % Of Corr. Nodes	43.7148	41.0635
Maximum % Of Corr. Nodes	100	100
Minimum Path Hubs %	0	0
Average Path Hubs %	38.1115	49.0896
Maximum Path Hubs %	100	100

Details about the values in these tables can be found in the corresponding documentation page .

You can download a compressed (zip) file with structure(s), 3D outputs (as PyMol and VMD scripts) and numerical data files (as csv and plain text files).

Download m4_on_ortoallo.zip<

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