psnGPCR

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Orange: nodes, hubs and links specific of mop_off network

Green: nodes, hubs and links shared by both networks

Purple: nodes, hubs and links specific of mop_on network

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Owner: the name of the network the link belong to or "Shared" if the corresponding link is present in both networks.

Strength: the interaction strength between the two nodes or 0 if the link is not present.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Owner	mop_off Int. Strength	mop_on Int. Strength	mop_off Hub1?	mop_on Hub1?	mop_off Hub2?	mop_on Hub2?	ConSurf1	ConSurf2
1	5x36	Lig	mop_off	100	0	No	No	Yes	Yes	4	0
2	5x40	Lig	mop_off	100	0	No	No	Yes	Yes	4	0
3	7x34	Lig	mop_off	100	0	Yes	Yes	Yes	Yes	5	0
4	1x35	1x39	mop_off	100	0	No	Yes	No	Yes	4	7
5	1x39	7x42	mop_off	100	0	No	Yes	Yes	Yes	7	7
6	1x42	7x47	mop_off	100	0	Yes	No	No	No	7	7
7	1x50	2x47	mop_off	100	0	Yes	No	No	No	9	9
8	1x52	8x54	mop_off	100	0	No	No	No	No	6	6
9	1x52	8x57	mop_off	100	0	No	No	No	No	6	5
10	1x53	7x53	mop_off	100	0	No	Yes	Yes	Yes	9	9
11	1x56	8x53	mop_off	100	0	No	No	No	No	7	5
12	1x60	8x53	mop_off	100	0	Yes	No	No	No	5	5
13	1x60	8x56	mop_off	100	0	Yes	No	No	No	5	4
14	2x40	I1x50	mop_off	100	0	No	No	No	No	8	7
15	8x50	I1x50	mop_off	100	0	Yes	Yes	No	No	9	7
16	2x41	4x42	mop_off	100	0	No	No	No	No	6	7
17	2x43	7x53	mop_off	100	0	No	No	Yes	Yes	8	9
18	2x45	3x42	mop_off	100	0	No	No	No	No	9	7
19	2x46	7x53	mop_off	100	0	No	Yes	Yes	Yes	9	9
20	2x56	3x28	mop_off	100	0	No	No	No	No	6	5
21	2x56	3x31	mop_off	100	0	No	No	No	No	6	5
22	3x30	3x34	mop_off	100	0	No	No	Yes	Yes	6	4
23	3x35	3x39	mop_off	100	0	No	No	No	No	8	9
24	3x36	6x52	mop_off	100	0	No	No	No	Yes	7	8
25	3x38	4x49	mop_off	100	0	No	Yes	No	No	7	7
26	3x39	6x44	mop_off	100	0	No	No	Yes	No	9	9
27	3x40	3x41	mop_off	100	0	No	No	No	No	8	6
28	3x40	6x44	mop_off	100	0	No	No	Yes	No	8	9
29	3x42	4x49	mop_off	100	0	No	No	No	No	7	7
30	3x43	6x41	mop_off	100	0	No	No	No	No	8	8
31	3x43	6x44	mop_off	100	0	No	No	Yes	No	8	9
32	3x46	6x37	mop_off	100	0	No	No	No	No	8	7
33	3x50	6x33	mop_off	100	0	No	No	No	No	9	7
34	3x50	6x34	mop_off	100	0	No	No	No	No	9	6
35	3x50	6x37	mop_off	100	0	No	No	No	No	9	7
36	3x54	6x30	mop_off	100	0	No	No	No	No	8	6
37	3x56	I2x52	mop_off	100	0	No	No	No	No	6	4
38	4x38	4x40	mop_off	100	0	No	No	No	No	7	3
39	5x40	6x55	mop_off	100	0	No	No	No	No	4	5
40	5x54	5x58	mop_off	100	0	No	No	Yes	Yes	8	9
41	5x54	6x41	mop_off	100	0	No	No	No	No	8	8
42	5x58	6x38	mop_off	100	0	Yes	Yes	No	No	9	4
43	6x28	6x32	mop_off	100	0	No	No	Yes	No	4	7
44	6x36	8x47	mop_off	100	0	No	No	No	No	8	8
45	6x39	7x56	mop_off	100	0	No	No	No	No	6	6
46	6x40	7x49	mop_off	100	0	No	No	Yes	Yes	8	9
47	6x44	7x45	mop_off	100	0	Yes	No	Yes	No	9	9
48	6x54	7x37	mop_off	100	0	No	No	No	No	4	6
49	6x58	7x30	mop_off	100	0	No	No	No	No	4	4
50	E3	E3	mop_off	100	0	Yes	No	Yes	No	2	2
51	1x55	8x57	mop_off	100	0	No	No	No	No	4	5
52	E2x52	Lig	mop_off	100	0	No	No	Yes	Yes	5	0
53	5x64	5x68	mop_off	100	0	No	No	No	No	5	6
54	6x31	I3	mop_off	100	0	No	No	Yes	Yes	5	4
55	6x27	6x31	mop_off	100	0	No	No	No	No	3	5
56	8x48	8x52	mop_off	100	0	No	No	No	No	4	4
57	E2	Lig	mop_off	100	0	Yes	Yes	Yes	Yes	4	0
58	E3	Lig	mop_off	100	0	Yes	No	Yes	Yes	2	0
59	3x29	E2x50	mop_off	33.3333	0	No	No	No	No	5	9
60	8x53	I1x50	mop_off	66.6667	0	No	No	No	No	5	7
61	1x42	7x43	mop_off	33.3333	0	Yes	No	No	No	7	5
62	2x37	2x39	mop_off	33.3333	0	No	No	No	No	8	8
63	3x33	5x39	mop_off	33.3333	0	No	No	No	No	4	5
64	2x39	6x33	mop_off	66.6667	0	No	No	No	No	8	7
65	5x33	5x37	mop_off	33.3333	0	No	No	No	No	2	3
66	I1x48	I1x51	mop_off	33.3333	0	No	No	No	No	6	6
67	6x43	7x45	mop_off	33.3333	0	No	No	Yes	No	6	9
68	3x51	5x61	mop_off	33.3333	0	Yes	Yes	No	No	8	8
69	E1x50	E2	mop_off	33.3333	0	Yes	Yes	Yes	Yes	8	4
70	2x38	I2x57	mop_off	33.3333	0	No	No	Yes	Yes	6	6
71	1x49	7x50	mop_off	66.6667	0	No	No	No	No	7	9
72	3x26	4x64	mop_off	0	0	No	No	No	No	6	4
73	5x45	5x48	mop_off	33.3333	0	No	No	No	No	4	5
74	6x57	6x61	mop_off	0	0	No	No	No	No	5	3
75	2x60	3x28	mop_off	33.3333	0	No	No	No	No	6	5
76	7x54	8x54	mop_off	33.3333	0	No	No	No	No	7	6
77	7x45	7x48	mop_off	33.3333	0	Yes	No	No	No	9	7
78	8x58	8x59	mop_off	33.3333	0	No	No	No	No	5	2
79	6x47	7x40	mop_off	33.3333	0	No	No	No	No	8	7
80	2x49	3x35	mop_off	0	0	No	No	No	No	8	8
81	1x60	I1x48	mop_off	33.3333	0	Yes	No	No	No	5	6
82	7x55	7x56	mop_off	33.3333	0	No	No	No	No	6	6
83	1x38	1x42	mop_off	33.3333	0	No	No	Yes	No	5	7
84	6x23	6x25	mop_off	33.3333	0	No	No	No	No	0	2
85	5x63	5x66	mop_off	33.3333	0	No	No	No	No	2	4
86	7x31	E3	mop_off	0	0	No	No	Yes	No	4	2
87	3x48	5x57	mop_off	0	0	No	No	No	No	6	7
88	4x59	4x63	mop_off	0	0	No	No	No	No	7	4
89	4x39	I1x51	mop_off	33.3333	0	No	No	No	No	1	6
90	7x28	7x31	mop_off	0	0	No	No	No	No	4	4
91	5x37	6x59	mop_off	0	0	No	No	No	No	3	4
92	3x55	I2x50	mop_off	33.3333	0	No	No	No	No	7	7
93	4x61	4x62	mop_off	33.3333	0	No	No	No	No	4	5
94	2x67	E1x49	mop_off	0	0	No	No	No	No	4	5
95	2x58	2x61	mop_off	0	0	No	No	No	No	8	6
96	7x31	7x32	mop_off	0	0	No	No	No	No	4	1
97	1x30	1x33	mop_off	0	0	No	No	No	No	2	4
98	1x33	1x36	mop_off	0	0	No	No	Yes	No	4	5
99	6x24	6x26	mop_off	0	0	No	No	No	No	0	4
100	I2x55	I2x56	mop_off	0	0	No	No	No	No	4	4
101	I2x50	I2x51	mop_off	0	0	No	No	No	No	7	5
102	2x54	2x55	mop_off	0	0	No	No	No	No	6	5
103	5x66	5x67	mop_off	0	0	No	No	No	No	4	4
104	5x67	I3	mop_off	0	0	No	No	Yes	Yes	4	4
105	5x58	5x59	mop_off	0	0	Yes	Yes	No	No	9	2
106	8x55	8x58	mop_off	0	0	No	No	No	No	5	5
107	3x32	Lig	Shared	100	100	No	Yes	Yes	Yes	6	0
108	3x33	Lig	Shared	100	100	No	No	Yes	Yes	4	0
109	3x36	Lig	Shared	100	100	No	No	Yes	Yes	7	0
110	5x43	Lig	Shared	100	100	No	No	Yes	Yes	5	0
111	6x51	Lig	Shared	100	100	No	No	Yes	Yes	6	0
112	6x52	Lig	Shared	100	100	No	Yes	Yes	Yes	8	0
113	6x55	Lig	Shared	100	100	No	No	Yes	Yes	5	0
114	7x38	Lig	Shared	100	100	No	No	Yes	Yes	5	0
115	7x42	Lig	Shared	100	100	Yes	Yes	Yes	Yes	7	0
116	1x35	2x64	Shared	100	100	No	Yes	No	Yes	4	5
117	1x36	2x65	Shared	100	100	Yes	No	No	No	5	5
118	1x39	2x57	Shared	100	100	No	Yes	Yes	Yes	7	7
119	1x47	2x54	Shared	100	100	No	No	No	No	6	6
120	1x48	1x49	Shared	100	0	No	No	No	No	4	7
121	1x50	2x50	Shared	100	100	Yes	No	No	Yes	9	9
122	1x50	7x50	Shared	100	100	Yes	No	No	No	9	9
123	1x54	2x44	Shared	100	100	No	No	No	Yes	7	6
124	1x55	1x59	Shared	100	100	No	No	No	No	4	4
125	1x57	2x44	Shared	100	100	No	No	No	Yes	7	6
126	1x57	8x50	Shared	100	100	No	No	Yes	Yes	7	9
127	1x59	1x60	Shared	100	100	No	No	Yes	No	4	5
128	2x37	2x40	Shared	100	100	No	No	No	No	8	8
129	2x40	8x50	Shared	100	100	No	No	Yes	Yes	8	9
130	2x41	4x46	Shared	100	23.0769	No	No	No	No	6	7
131	2x42	3x45	Shared	100	100	Yes	Yes	No	No	7	7
132	2x42	3x46	Shared	100	100	Yes	Yes	No	No	7	8
133	2x42	3x49	Shared	100	100	Yes	Yes	No	No	7	8
134	2x42	4x42	Shared	100	100	Yes	Yes	No	No	7	7
135	2x45	4x46	Shared	100	100	No	No	No	No	9	7
136	2x45	4x50	Shared	100	100	No	No	Yes	Yes	9	9
137	2x50	7x46	Shared	100	100	No	Yes	No	No	9	9
138	2x50	7x49	Shared	100	100	No	Yes	Yes	Yes	9	9
139	2x53	3x35	Shared	100	30.7692	No	No	No	No	7	8
140	2x57	7x42	Shared	100	100	Yes	Yes	Yes	Yes	7	7
141	2x59	E1x52	Shared	100	100	No	No	Yes	Yes	6	7
142	2x60	7x42	Shared	100	100	No	No	Yes	Yes	6	7
143	2x62	E1x52	Shared	100	100	No	No	Yes	Yes	5	7
144	2x63	E1x50	Shared	100	100	No	No	Yes	Yes	6	8
145	2x64	7x35	Shared	100	100	No	Yes	No	Yes	5	4
146	2x66	E1x51	Shared	100	46.1538	No	No	No	No	3	4
147	E1x49	E2	Shared	100	100	No	No	Yes	Yes	5	4
148	E1x50	E1x52	Shared	100	100	Yes	Yes	Yes	Yes	8	7
149	3x25	E1x50	Shared	100	100	No	No	Yes	Yes	9	8
150	E1x50	E2x50	Shared	100	100	Yes	Yes	No	No	8	9
151	E1x51	E1x52	Shared	100	100	No	No	Yes	Yes	4	7
152	3x24	E1x52	Shared	100	100	No	No	Yes	Yes	6	7
153	3x22	E2	Shared	100	100	No	No	Yes	Yes	1	4
154	3x25	E2x50	Shared	100	100	No	No	No	No	9	9
155	3x30	4x61	Shared	100	100	No	No	No	No	6	4
156	3x32	7x42	Shared	100	100	No	Yes	Yes	Yes	6	7
157	3x33	4x60	Shared	100	100	No	No	No	No	4	5
158	3x34	4x50	Shared	100	100	Yes	Yes	Yes	Yes	4	9
159	3x34	4x54	Shared	100	30.7692	Yes	Yes	No	No	4	3
160	3x34	4x57	Shared	100	30.7692	Yes	Yes	No	No	4	7
161	3x36	6x48	Shared	100	100	No	No	Yes	Yes	7	8
162	3x37	4x56	Shared	100	100	No	Yes	No	No	7	4
163	3x37	5x43	Shared	100	100	No	Yes	No	No	7	5
164	3x37	5x461	Shared	100	30.7692	No	Yes	No	No	7	6
165	3x38	4x50	Shared	100	100	No	Yes	Yes	Yes	7	9
166	3x38	4x53	Shared	100	100	No	Yes	No	No	7	8
167	3x40	5x50	Shared	100	53.8462	No	No	No	No	8	9
168	3x41	4x49	Shared	100	100	No	No	No	No	6	7
169	3x44	5x53	Shared	100	30.7692	No	No	No	No	7	7
170	3x47	5x54	Shared	100	100	No	No	No	No	9	8
171	3x47	5x58	Shared	100	100	No	No	Yes	Yes	9	9
172	3x49	I2x57	Shared	100	100	No	No	Yes	Yes	8	6
173	3x51	3x55	Shared	100	100	Yes	Yes	No	No	8	7
174	3x51	3x56	Shared	100	100	Yes	Yes	No	No	8	6
175	3x51	5x60	Shared	100	100	Yes	Yes	No	No	8	4
176	3x53	I2x57	Shared	100	100	No	No	Yes	Yes	8	6
177	3x55	5x64	Shared	100	23.0769	No	No	No	No	7	5
178	4x38	4x39	Shared	100	23.0769	No	No	No	No	7	1
179	4x38	4x41	Shared	100	100	No	No	No	No	7	4
180	4x54	4x58	Shared	100	53.8462	No	No	No	No	3	3
181	E2	E2	Shared	100	100	Yes	Yes	Yes	Yes	4	4
182	E2	E2x51	Shared	100	100	Yes	Yes	No	No	4	3
183	E2	E2x52	Shared	100	100	Yes	Yes	No	No	4	5
184	5x35	E2	Shared	100	100	No	No	Yes	Yes	3	4
185	5x36	E2	Shared	100	100	No	No	Yes	Yes	4	4
186	5x34	5x35	Shared	100	100	No	No	No	No	3	3
187	5x36	5x40	Shared	100	100	No	No	No	No	4	4
188	5x44	5x48	Shared	100	100	No	Yes	No	No	5	5
189	5x44	6x56	Shared	100	100	No	Yes	No	No	5	6
190	5x45	5x46	Shared	100	100	No	No	No	No	4	4
191	5x47	6x49	Shared	100	100	Yes	Yes	Yes	Yes	8	5
192	5x47	6x52	Shared	100	100	Yes	Yes	No	Yes	8	8
193	5x58	5x61	Shared	100	46.1538	Yes	Yes	No	No	9	8
194	6x29	6x33	Shared	100	15.3846	No	No	No	No	5	7
195	6x36	7x56	Shared	100	100	No	No	No	No	8	6
196	6x40	7x53	Shared	100	100	No	No	Yes	Yes	8	9
197	6x44	6x48	Shared	100	100	Yes	No	Yes	Yes	9	8
198	6x47	7x45	Shared	100	100	No	No	Yes	No	8	9
199	6x48	7x45	Shared	100	100	Yes	Yes	Yes	No	8	9
200	6x54	7x33	Shared	100	100	No	No	No	No	4	5
201	6x54	7x34	Shared	100	100	No	No	Yes	Yes	4	5
202	6x58	7x34	Shared	100	100	No	No	Yes	Yes	4	5
203	7x30	E3	Shared	100	100	No	No	Yes	No	4	2
204	7x34	7x35	Shared	100	100	Yes	Yes	No	Yes	5	4
205	7x34	7x38	Shared	100	100	Yes	Yes	No	No	5	5
206	7x45	7x49	Shared	100	100	Yes	No	Yes	Yes	9	9
207	7x49	7x53	Shared	100	100	Yes	Yes	Yes	Yes	9	9
208	8x47	8x50	Shared	100	100	No	No	Yes	Yes	8	9
209	8x48	8x51	Shared	100	100	No	No	No	No	4	8
210	8x49	8x52	Shared	100	100	No	No	No	No	6	4
211	2x42	4x45	Shared	100	30.7692	Yes	Yes	No	No	7	5
212	2x60	Lig	Shared	100	100	No	No	Yes	Yes	6	0
213	3x22	3x26	Shared	100	30.7692	No	No	No	No	1	6
214	3x54	5x61	Shared	100	100	No	No	No	No	8	8
215	6x27	I3	Shared	100	23.0769	No	No	Yes	Yes	3	4
216	6x29	6x32	Shared	100	100	No	No	Yes	No	5	7
217	1x60	8x57	Shared	100	100	Yes	No	No	No	5	5
218	Lig	Lig	Shared	100	100	Yes	Yes	Yes	Yes	0	0
219	6x48	7x41	Shared	33.3333	30.7692	Yes	Yes	No	No	8	7
220	3x41	4x52	Shared	66.6667	7.69231	No	No	No	No	6	4
221	5x44	5x47	Shared	66.6667	100	No	Yes	Yes	Yes	5	8
222	5x31	5x33	Shared	33.3333	100	No	No	No	No	1	2
223	3x44	5x50	Shared	66.6667	100	No	No	No	No	7	9
224	3x51	5x57	Shared	66.6667	100	Yes	Yes	No	No	8	7
225	6x32	8x48	Shared	33.3333	100	Yes	No	No	No	7	4
226	7x29	7x33	Shared	66.6667	30.7692	No	No	No	No	2	5
227	6x23	6x26	Shared	33.3333	100	No	No	No	No	0	4
228	1x58	2x44	Shared	66.6667	23.0769	No	No	No	Yes	3	6
229	6x45	6x49	Shared	33.3333	100	No	No	Yes	Yes	5	5
230	6x43	7x52	Shared	33.3333	100	No	No	No	No	6	8
231	3x54	5x65	Shared	66.6667	100	No	No	No	No	8	8
232	6x49	6x50	Shared	66.6667	100	Yes	Yes	No	No	5	9
233	8x51	8x55	Shared	33.3333	7.69231	No	No	No	No	8	5
234	5x42	5x46	Shared	33.3333	38.4615	No	No	No	No	3	4
235	2x48	4x50	Shared	33.3333	100	No	No	Yes	Yes	6	9
236	1x43	2x57	Shared	33.3333	100	No	No	Yes	Yes	6	7
237	4x63	E2	Shared	33.3333	100	No	No	Yes	Yes	4	4
238	6x26	I3	Shared	33.3333	15.3846	No	No	Yes	Yes	4	4
239	1x43	2x58	Shared	66.6667	100	No	No	No	No	6	8
240	1x42	2x57	Shared	33.3333	0	Yes	No	Yes	Yes	7	7
241	2x41	4x43	Shared	0	23.0769	No	No	No	No	6	2
242	I1x49	I1x51	Shared	33.3333	23.0769	No	No	No	No	5	6
243	5x48	5x52	Shared	0	0	No	No	No	No	5	3
244	7x27	7x30	Shared	33.3333	0	No	No	No	No	1	4
245	5x34	5x38	Shared	33.3333	38.4615	No	No	No	No	3	4
246	1x45	7x47	Shared	66.6667	46.1538	No	No	No	No	5	7
247	5x33	5x34	Shared	33.3333	100	No	No	No	No	2	3
248	5x49	5x50	Shared	0	38.4615	No	No	No	No	5	9
249	5x32	E2	Shared	33.3333	23.0769	No	No	Yes	Yes	3	4
250	5x47	5x51	Shared	33.3333	100	Yes	Yes	No	No	8	6
251	5x65	I3	Shared	33.3333	46.1538	No	No	Yes	Yes	8	4
252	3x52	I2x56	Shared	33.3333	100	No	No	No	No	5	4
253	1x50	2x51	Shared	0	100	Yes	No	No	No	9	7
254	3x48	3x52	Shared	33.3333	7.69231	No	No	No	No	6	5
255	4x47	4x51	Shared	33.3333	0	No	No	No	No	4	4
256	1x47	1x51	Shared	33.3333	100	No	No	No	No	6	4
257	7x36	7x40	Shared	33.3333	30.7692	No	No	No	No	5	7
258	1x31	1x35	Shared	33.3333	0	No	No	No	Yes	3	4
259	1x46	7x47	Shared	0	100	No	No	No	No	8	7
260	3x23	3x27	Shared	0	0	No	No	No	No	2	5
261	3x27	3x31	Shared	0	7.69231	No	No	No	No	5	5
262	6x60	6x61	Shared	0	0	No	No	No	No	5	3
263	2x48	2x52	Shared	0	46.1538	No	No	No	No	6	7
264	5x60	5x63	Shared	0	0	No	No	No	No	4	2
265	1x46	2x54	Shared	0	23.0769	No	No	No	No	8	6
266	I2x54	I2x55	Shared	33.3333	0	No	No	No	No	5	4
267	6x32	6x35	Shared	33.3333	7.69231	Yes	No	No	No	7	6
268	1x32	2x64	Shared	33.3333	23.0769	No	No	No	Yes	4	5
269	1x29	1x32	Shared	33.3333	0	No	No	No	No	2	4
270	1x30	1x34	Shared	0	0	No	No	No	No	2	4
271	5x51	5x55	Shared	0	0	No	No	No	No	6	4
272	1x36	2x61	Shared	33.3333	100	Yes	No	No	No	5	6
273	6x49	6x53	Shared	0	7.69231	Yes	Yes	No	No	5	6
274	5x56	5x60	Shared	0	0	No	No	No	No	4	4
275	6x53	6x57	Shared	0	7.69231	No	No	No	No	6	5
276	3x21	E1x50	Shared	0	0	No	No	Yes	Yes	7	8
277	I2x53	I2x57	Shared	0	0	No	No	Yes	Yes	6	6
278	4x44	4x48	Shared	0	0	No	No	No	No	3	4
279	1x44	1x45	Shared	0	0	No	No	No	No	5	5
280	1x38	7x39	Shared	0	100	No	No	No	No	5	4
281	1x36	1x40	Shared	0	7.69231	Yes	No	No	No	5	4
282	5x41	5x45	Shared	0	7.69231	No	No	No	No	4	4
283	4x41	4x44	Shared	0	0	No	No	No	No	4	3
284	7x51	7x55	Shared	0	100	No	No	No	No	6	6
285	2x55	2x56	Shared	0	0	No	No	No	No	5	6
286	1x41	1x45	Shared	0	0	No	No	No	No	5	5
287	2x63	Lig	mop_on	0	100	No	No	Yes	Yes	6	0
288	3x29	Lig	mop_on	0	100	No	No	Yes	Yes	5	0
289	1x35	7x35	mop_on	0	100	No	Yes	No	Yes	4	4
290	1x39	7x35	mop_on	0	100	No	Yes	No	Yes	7	4
291	1x39	7x38	mop_on	0	100	No	Yes	No	No	7	5
292	1x53	7x54	mop_on	0	100	No	Yes	No	No	9	7
293	1x54	2x48	mop_on	0	100	No	No	No	No	7	6
294	2x40	I1x48	mop_on	0	100	No	No	No	No	8	6
295	2x44	I1x50	mop_on	0	100	No	Yes	No	No	6	7
296	2x42	4x46	mop_on	0	100	Yes	Yes	No	No	7	7
297	2x43	8x50	mop_on	0	100	No	No	Yes	Yes	8	9
298	2x46	2x50	mop_on	0	100	No	Yes	No	Yes	9	9
299	2x46	3x42	mop_on	0	100	No	Yes	No	No	9	7
300	2x46	3x43	mop_on	0	100	No	Yes	No	No	9	8
301	2x46	7x49	mop_on	0	100	No	Yes	Yes	Yes	9	9
302	2x50	3x39	mop_on	0	100	No	Yes	No	No	9	9
303	2x52	3x35	mop_on	0	100	No	No	No	No	7	8
304	2x56	3x32	mop_on	0	100	No	No	No	Yes	6	6
305	2x59	3x28	mop_on	0	100	No	No	No	No	6	5
306	2x60	3x32	mop_on	0	100	No	No	No	Yes	6	6
307	3x31	3x35	mop_on	0	100	No	No	No	No	5	8
308	3x34	3x38	mop_on	0	100	Yes	Yes	No	Yes	4	7
309	3x34	4x53	mop_on	0	100	Yes	Yes	No	No	4	8
310	3x36	3x37	mop_on	0	100	No	No	No	Yes	7	7
311	3x37	3x41	mop_on	0	100	No	Yes	No	No	7	6
312	3x40	6x48	mop_on	0	100	No	No	Yes	Yes	8	8
313	3x43	7x49	mop_on	0	100	No	No	Yes	Yes	8	9
314	3x43	7x53	mop_on	0	100	No	No	Yes	Yes	8	9
315	3x45	4x49	mop_on	0	100	No	No	No	No	7	7
316	3x46	7x53	mop_on	0	100	No	No	Yes	Yes	8	9
317	3x47	5x57	mop_on	0	100	No	No	No	No	9	7
318	3x50	5x58	mop_on	0	100	No	No	Yes	Yes	9	9
319	3x50	7x53	mop_on	0	100	No	No	Yes	Yes	9	9
320	5x31	E2	mop_on	0	100	No	No	Yes	Yes	1	4
321	5x44	6x52	mop_on	0	100	No	Yes	No	Yes	5	8
322	5x54	6x44	mop_on	0	100	No	No	Yes	No	8	9
323	5x58	6x37	mop_on	0	100	Yes	Yes	No	No	9	7
324	5x62	6x34	mop_on	0	100	No	No	No	No	5	6
325	5x62	6x37	mop_on	0	100	No	No	No	No	5	7
326	5x68	I3	mop_on	0	100	No	No	Yes	Yes	6	4
327	6x30	I3	mop_on	0	100	No	No	Yes	Yes	6	4
328	6x25	6x28	mop_on	0	100	No	No	No	No	2	4
329	6x40	7x52	mop_on	0	100	No	No	No	No	8	8
330	6x48	6x52	mop_on	0	100	Yes	Yes	No	Yes	8	8
331	6x51	7x37	mop_on	0	100	No	No	No	No	6	6
332	6x54	7x30	mop_on	0	100	No	No	No	No	4	4
333	8x47	8x49	mop_on	0	100	No	No	No	No	8	6
334	6x48	Lig	mop_on	0	100	Yes	Yes	Yes	Yes	8	0
335	3x28	E1x50	mop_on	0	100	No	No	Yes	Yes	5	8
336	5x39	E2	mop_on	0	61.5385	No	No	Yes	Yes	5	4
337	5x40	6x59	mop_on	0	30.7692	No	No	No	No	4	4
338	3x25	E2	mop_on	0	46.1538	No	No	Yes	Yes	9	4
339	4x41	4x45	mop_on	0	46.1538	No	No	No	No	4	5
340	1x53	2x47	mop_on	0	46.1538	No	Yes	No	No	9	9
341	5x58	6x41	mop_on	0	46.1538	Yes	Yes	No	No	9	8
342	1x39	2x61	mop_on	0	38.4615	No	Yes	No	No	7	6
343	1x52	7x55	mop_on	0	53.8462	No	No	No	No	6	6
344	1x43	1x47	mop_on	0	15.3846	No	No	No	No	6	6
345	4x40	4x44	mop_on	0	38.4615	No	No	No	No	3	3
346	2x49	3x38	mop_on	0	23.0769	No	No	No	Yes	8	7
347	1x56	8x54	mop_on	0	46.1538	No	No	No	No	7	6
348	6x50	7x40	mop_on	0	30.7692	No	No	No	No	9	7
349	1x53	7x50	mop_on	0	61.5385	No	Yes	No	No	9	9
350	1x53	7x55	mop_on	0	30.7692	No	Yes	No	No	9	6
351	2x39	I2x57	mop_on	0	30.7692	No	No	Yes	Yes	8	6
352	6x43	7x48	mop_on	0	30.7692	No	No	No	No	6	7
353	3x29	4x64	mop_on	0	38.4615	No	No	No	No	5	4
354	I2x52	I2x56	mop_on	0	23.0769	No	No	No	No	4	4
355	1x56	8x50	mop_on	0	15.3846	No	No	Yes	Yes	7	9
356	6x56	6x60	mop_on	0	0	No	No	No	No	6	5
357	2x64	7x31	mop_on	0	38.4615	No	Yes	No	No	5	4
358	5x64	5x67	mop_on	0	7.69231	No	No	No	No	5	4
359	3x49	I2x56	mop_on	0	46.1538	No	No	No	No	8	4
360	1x48	1x52	mop_on	0	7.69231	No	No	No	No	4	6
361	6x31	6x35	mop_on	0	23.0769	No	No	No	No	5	6
362	1x31	7x28	mop_on	0	15.3846	No	No	No	No	3	4
363	4x58	4x59	mop_on	0	7.69231	No	No	No	No	3	7
364	1x38	7x36	mop_on	0	23.0769	No	No	No	No	5	5
365	6x47	7x43	mop_on	0	23.0769	No	No	No	No	8	5
366	1x31	7x32	mop_on	0	15.3846	No	No	No	No	3	1
367	8x56	8x57	mop_on	0	7.69231	No	No	No	No	4	5
368	2x38	4x42	mop_on	0	0	No	No	No	No	6	7
369	1x56	1x60	mop_on	0	23.0769	No	No	Yes	No	7	5
370	6x39	7x52	mop_on	0	0	No	No	No	No	6	8
371	5x38	5x42	mop_on	0	7.69231	No	No	No	No	4	3
372	5x62	5x66	mop_on	0	0	No	No	No	No	5	4
373	3x26	4x61	mop_on	0	7.69231	No	No	No	No	6	4
374	7x56	8x51	mop_on	0	15.3846	No	No	No	No	6	8
375	5x65	6x33	mop_on	0	0	No	No	No	No	8	7
376	3x56	I2x50	mop_on	0	0	No	No	No	No	6	7
377	6x34	6x38	mop_on	0	0	No	No	No	No	6	4
378	5x37	5x40	mop_on	0	7.69231	No	No	No	No	3	4
379	1x29	1x33	mop_on	0	15.3846	No	No	No	No	2	4
380	4x58	4x62	mop_on	0	7.69231	No	No	No	No	3	5
381	2x37	I1x51	mop_on	0	0	No	No	No	No	8	6
382	2x66	2x67	mop_on	0	0	No	No	No	No	3	4
383	6x28	6x31	mop_on	0	15.3846	No	No	No	No	4	5
384	6x24	6x28	mop_on	0	7.69231	No	No	No	No	0	4
385	I2x52	I2x55	mop_on	0	7.69231	No	No	No	No	4	4
386	8x57	8x59	mop_on	0	7.69231	No	No	No	No	5	2
387	1x34	1x35	mop_on	0	7.69231	No	No	No	Yes	4	4
388	I2x51	I2x52	mop_on	0	0	No	No	No	No	5	4
389	1x37	1x40	mop_on	0	0	No	No	No	No	5	4
390	8x53	I1x48	mop_on	0	0	No	No	No	No	5	6
391	Lig	NT	mop_on	0	7.69231	Yes	Yes	No	No	0	0
392	4x52	4x55	mop_on	0	0	No	No	No	No	4	4
393	4x51	4x54	mop_on	0	0	No	No	No	No	4	3

Orange: nodes, hubs and links specific of mop_off network

Green: nodes, hubs and links shared by both networks

Purple: nodes, hubs and links specific of mop_on network

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Owner: the name of the network the hub belong to or "Shared" if the corresponding hub is present in both networks.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub in the corresponding network.

Num Of Links: the number of links of the corresponding hub in the corresponding network.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Owner	mop_off Avg Int. Strength	mop_on Avg Int. Strength	mop_off Num Of Links	mop_on Num Of Links	ConSurf
1	1x36	mop_off	0	0	4	3	5
2	1x42	mop_off	0	0	4	1	7
3	1x50	mop_off	0	15.3846	4	3	9
4	1x60	mop_off	33.3333	0	5	3	5
5	6x32	mop_off	33.3333	0	4	3	7
6	6x44	mop_off	100	23.0769	5	2	9
7	E3	mop_off	0	15.3846	5	1	2
8	7x45	mop_off	33.3333	53.8462	6	3	9
9	Lig	Shared	100	100	18	16	0
10	2x42	Shared	66.6667	92.3077	5	6	7
11	2x57	Shared	0	0	4	4	7
12	E1x50	Shared	66.6667	100	6	6	8
13	E1x52	Shared	66.6667	84.6154	5	5	7
14	3x34	Shared	66.6667	69.2308	4	5	4
15	3x51	Shared	66.6667	76.9231	5	4	8
16	I2x57	Shared	33.3333	0	4	4	6
17	4x50	Shared	66.6667	61.5385	4	4	9
18	E2	Shared	100	100	12	13	4
19	5x47	Shared	66.6667	38.4615	4	4	8
20	5x58	Shared	33.3333	84.6154	5	5	9
21	I3	Shared	33.3333	46.1538	5	5	4
22	6x48	Shared	66.6667	100	4	7	8
23	6x49	Shared	0	7.69231	4	4	5
24	7x34	Shared	66.6667	92.3077	5	4	5
25	7x42	Shared	66.6667	61.5385	5	4	7
26	7x49	Shared	0	69.2308	4	5	9
27	7x53	Shared	66.6667	100	5	5	9
28	8x50	Shared	66.6667	61.5385	4	5	9
29	1x35	mop_on	33.3333	0	3	4	4
30	1x39	mop_on	33.3333	38.4615	3	4	7
31	1x53	mop_on	0	0	1	4	9
32	2x44	mop_on	0	7.69231	3	4	6
33	2x46	mop_on	0	46.1538	1	4	9
34	2x50	mop_on	0	100	3	5	9
35	2x64	mop_on	0	7.69231	3	4	5
36	3x32	mop_on	0	38.4615	2	4	6
37	3x37	mop_on	33.3333	38.4615	3	5	7
38	3x38	mop_on	0	38.4615	3	4	7
39	5x44	mop_on	0	46.1538	3	4	5
40	6x52	mop_on	0	30.7692	3	4	8
41	7x35	mop_on	0	53.8462	2	4	4

Orange: nodes, hubs and links specific of mop_off network

Green: nodes, hubs and links shared by both networks

Purple: nodes, hubs and links specific of mop_on network

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Owner: the name of the network the link belong to or "Shared" if the corresponding link is present in both networks.

Recurrence: the relative Recurrence in the filtered pool of shortest paths.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Owner	mop_off Recurrence	mop_on Recurrence	mop_off Hub1?	mop_on Hub1?	mop_off Hub2?	mop_on Hub2?	ConSurf1	ConSurf2
1	2x58	2x61	mop_off	10.9162	0	No	No	No	No	8	6
2	1x43	2x58	mop_off	12.4282	2.02515	No	No	No	No	6	8
3	1x42	2x57	mop_off	13.9159	2.02515	Yes	No	Yes	Yes	7	7
4	2x56	3x28	mop_off	11.8778	0	No	No	No	No	6	5
5	2x60	3x28	mop_off	13.0813	0	No	No	No	No	6	5
6	2x60	Lig	mop_off	13.3293	1.7852	No	No	Yes	Yes	6	0
7	3x36	6x48	mop_off	100	3.46003	No	No	Yes	Yes	7	8
8	1x60	8x53	mop_off	26.4469	0	Yes	No	No	No	5	5
9	8x53	I1x50	mop_off	29.1684	0	No	No	No	No	5	7
10	2x40	I1x50	mop_off	29.1261	0	No	No	No	No	8	7
11	2x37	2x40	mop_off	45.4732	6.97764	No	No	No	No	8	8
12	2x37	2x39	mop_off	46.6586	0	No	No	No	No	8	8
13	2x39	6x33	mop_off	47.8077	0	No	No	No	No	8	7
14	3x50	6x33	mop_off	60.5624	0	No	No	No	No	9	7
15	3x50	6x37	mop_off	62.4493	0	No	No	No	No	9	7
16	3x46	6x37	mop_off	63.3263	0	No	No	No	No	8	7
17	2x42	4x42	mop_off	71.5331	4.65976	Yes	Yes	No	No	7	7
18	2x41	4x42	mop_off	72.404	0	No	No	No	No	6	7
19	2x41	4x46	mop_off	74.1095	4.65976	No	No	No	No	6	7
20	2x45	3x42	mop_off	71.1823	0	No	No	No	No	9	7
21	3x42	4x49	mop_off	71.8718	0	No	No	No	No	7	7
22	3x40	3x41	mop_off	87.2815	0	No	No	No	No	8	6
23	3x40	6x44	mop_off	90.2449	0	No	No	Yes	No	8	9
24	3x38	4x49	mop_off	13.5047	0	No	Yes	No	No	7	7
25	3x38	4x50	mop_off	12.1379	6.84807	No	Yes	Yes	Yes	7	9
26	E1x50	E2	mop_off	17.7926	0	Yes	Yes	Yes	Yes	8	4
27	E2	Lig	mop_off	38.7179	0	Yes	Yes	Yes	Yes	4	0
28	7x34	Lig	mop_off	13.2991	0	Yes	Yes	Yes	Yes	5	0
29	3x43	6x44	mop_off	49.0112	0	No	No	Yes	No	8	9
30	3x43	6x41	mop_off	47.8621	0	No	No	No	No	8	8
31	5x54	6x41	mop_off	46.7009	0	No	No	No	No	8	8
32	5x54	5x58	mop_off	44.1427	0	No	No	Yes	Yes	8	9
33	3x51	5x61	mop_off	26.1687	0	Yes	Yes	No	No	8	8
34	1x60	I1x48	mop_off	13.8071	0	Yes	No	No	No	5	6
35	I1x48	I1x51	mop_off	12.3193	0	No	No	No	No	6	6
36	5x44	5x47	mop_off	12.3314	0.340724	No	Yes	Yes	Yes	5	8
37	6x32	8x48	mop_off	10.6259	6.56013	Yes	No	No	No	7	4
38	5x65	I3	mop_off	10.88	7.88943	No	No	Yes	Yes	8	4
39	3x36	6x52	mop_off	17.345	0	No	No	No	Yes	7	8
40	6x44	7x45	mop_off	15.9298	0	Yes	No	Yes	No	9	9
41	1x43	2x57	Shared	13.928	19.8628	No	No	Yes	Yes	6	7
42	2x57	7x42	Shared	26.8521	22.1374	Yes	Yes	Yes	Yes	7	7
43	2x50	7x49	Shared	12.3314	17.732	No	Yes	Yes	Yes	9	9
44	7x45	7x49	Shared	20.8406	62.0357	Yes	No	Yes	Yes	9	9
45	6x48	7x45	Shared	14.3211	62.3956	Yes	Yes	Yes	No	8	9
46	3x36	Lig	Shared	82.2558	39.3464	No	No	Yes	Yes	7	0
47	2x42	3x46	Shared	64.3302	68.5478	Yes	Yes	No	No	7	8
48	2x45	4x46	Shared	74.9441	94.3133	No	No	No	No	9	7
49	3x41	4x49	Shared	86.0115	74.4169	No	No	No	No	6	7
50	6x44	6x48	Shared	86.0962	27.7762	Yes	No	Yes	Yes	9	8
51	2x40	8x50	Shared	15.1376	13.8641	No	No	Yes	Yes	8	9
52	3x34	4x50	Shared	10.8316	20.5538	Yes	Yes	Yes	Yes	4	9
53	5x58	5x61	Shared	40.6592	27.2387	Yes	Yes	No	No	9	8
54	3x54	5x61	Shared	15.0045	26.0726	No	No	No	No	8	8
55	5x35	E2	Shared	10.3538	14.0752	No	No	Yes	Yes	3	4
56	6x52	Lig	Shared	10.5171	10.932	No	Yes	Yes	Yes	8	0
57	5x47	6x52	Shared	26.6646	16.062	Yes	Yes	No	Yes	8	8
58	5x47	6x49	Shared	10.8316	12.434	Yes	Yes	Yes	Yes	8	5
59	6x29	6x33	Shared	16.5528	15.5677	No	No	No	No	5	7
60	6x29	6x32	Shared	15.0892	14.3104	No	No	Yes	No	5	7
61	3x54	5x65	Shared	12.3677	25.0072	No	No	No	No	8	8
62	7x42	Lig	Shared	31.2005	23.1596	Yes	Yes	Yes	Yes	7	0
63	1x35	7x35	mop_on	0	22.6269	No	Yes	No	Yes	4	4
64	1x39	7x35	mop_on	0	23.5531	No	Yes	No	Yes	7	4
65	1x39	7x38	mop_on	0	32.959	No	Yes	No	No	7	5
66	7x38	Lig	mop_on	1.37285	69.2437	No	No	Yes	Yes	5	0
67	7x34	7x35	mop_on	5.38857	22.6893	Yes	Yes	No	Yes	5	4
68	7x34	7x38	mop_on	0.0786211	36.1887	Yes	Yes	No	No	5	5
69	1x39	2x61	mop_on	0	10.1449	No	Yes	No	No	7	6
70	1x46	2x54	mop_on	0.852737	10.0489	No	No	No	No	8	6
71	1x47	2x54	mop_on	3.18718	12.0309	No	No	No	No	6	6
72	1x43	1x47	mop_on	0	15.966	No	No	No	No	6	6
73	1x50	2x50	mop_on	9.31962	14.248	Yes	No	No	Yes	9	9
74	6x48	Lig	mop_on	0	72.1854	Yes	Yes	Yes	Yes	8	0
75	1x50	7x50	mop_on	4.71122	11.743	Yes	No	No	No	9	9
76	1x53	7x50	mop_on	0	10.4761	No	Yes	No	No	9	9
77	1x54	2x48	mop_on	0	52.0875	No	No	No	No	7	6
78	2x48	4x50	mop_on	3.15089	66.6331	No	No	Yes	Yes	6	9
79	2x45	4x50	mop_on	4.69912	92.3985	No	No	Yes	Yes	9	9
80	2x42	4x46	mop_on	0	100	Yes	Yes	No	No	7	7
81	2x42	3x45	mop_on	1.57847	73.006	Yes	Yes	No	No	7	7
82	3x45	4x49	mop_on	0	73.6731	No	No	No	No	7	7
83	3x37	3x41	mop_on	0	77.6994	No	Yes	No	No	7	6
84	3x36	3x37	mop_on	0	42.2545	No	No	No	Yes	7	7
85	3x37	5x43	mop_on	4.71122	39.2792	No	Yes	No	No	7	5
86	5x43	Lig	mop_on	6.09011	39.7351	No	No	Yes	Yes	5	0
87	3x46	7x53	mop_on	0	69.0085	No	No	Yes	Yes	8	9
88	7x49	7x53	mop_on	5.9873	59.5595	Yes	Yes	Yes	Yes	9	9
89	1x54	2x44	mop_on	1.57847	49.9712	No	No	No	Yes	7	6
90	1x56	1x60	mop_on	0	12.8371	No	No	Yes	No	7	5
91	1x56	8x50	mop_on	0	17.4009	No	No	Yes	Yes	7	9
92	1x57	8x50	mop_on	6.25945	41.4003	No	No	Yes	Yes	7	9
93	1x57	2x44	mop_on	4.71122	43.5646	No	No	No	Yes	7	6
94	2x42	3x49	mop_on	7.59601	27.3827	Yes	Yes	No	No	7	8
95	2x48	2x52	mop_on	1.57847	13.8737	No	No	No	No	6	7
96	2x52	3x35	mop_on	0	11.5846	No	No	No	No	7	8
97	E1x50	E1x52	mop_on	9.35591	14.0369	Yes	Yes	Yes	Yes	8	7
98	2x63	E1x50	mop_on	1.58452	68.1975	No	No	Yes	Yes	6	8
99	2x63	Lig	mop_on	0	69.6996	No	No	Yes	Yes	6	0
100	3x25	E2	mop_on	0	45.3642	No	No	Yes	Yes	9	4
101	3x25	E1x50	mop_on	1.57242	47.0967	No	No	Yes	Yes	9	8
102	3x47	5x54	mop_on	1.37889	26.6436	No	No	No	No	9	8
103	5x54	6x44	mop_on	0	26.8404	No	No	Yes	No	8	9
104	3x47	5x57	mop_on	0	12.9571	No	No	No	No	9	7
105	3x47	5x58	mop_on	0.193529	25.9766	No	No	Yes	Yes	9	9
106	3x51	5x57	mop_on	9.31962	11.6902	Yes	Yes	No	No	8	7
107	3x49	I2x56	mop_on	0	16.1532	No	No	No	No	8	4
108	4x41	4x45	mop_on	0	13.8737	No	No	No	No	4	5
109	2x42	4x45	mop_on	1.57847	16.1532	Yes	Yes	No	No	7	5
110	5x34	5x35	mop_on	8.8358	12.0933	No	No	No	No	3	3
111	5x34	5x38	mop_on	1.58452	10.1449	No	No	No	No	3	4
112	5x65	6x33	mop_on	0	16.6571	No	No	No	No	8	7
113	6x54	7x34	mop_on	5.9752	12.1029	No	No	Yes	Yes	4	5
114	3x34	4x54	mop_on	3.15089	13.8449	Yes	Yes	No	No	4	3
115	2x64	7x35	mop_on	3.98549	18.5382	No	Yes	No	Yes	5	4
116	1x31	1x35	mop_on	1.59661	11.4166	No	No	No	Yes	3	4
117	1x32	2x64	mop_on	2.99365	11.4262	No	No	No	Yes	4	5
118	6x48	6x52	mop_on	0	14.3104	Yes	Yes	No	Yes	8	8
119	3x50	7x53	mop_on	0	21.0673	No	No	Yes	Yes	9	9
120	3x50	5x58	mop_on	0	20.2419	No	No	Yes	Yes	9	9

Here, those paths that begin and end at given residue pair(s) or that pass through a residue are used to generate a novel metapath. Such a path filtering is particularly recommended if some information on allosteric residues is available. The selection syntax for a residue pair ("Pairs") is C:C:c534,A:A:?600 (the lower-case "c" stands for cytosine and "?" indicates any non standard amino acid or nucleotide residue). Selection of more than one apical residue pair has the following syntax: C:C:c534,A:A:?600,C:C:c534,A:A:E41. Only one residue can be selected as a tail ("Tail"). For midway residue(s), each residue must be separated by a comma as well e.g. A:A:?600,A:A:E41.

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Node1	Node2	Owner	Net1LinkStrength	Net2LinkStrength	Comm1	Comm2	Node1Shell	Node2Shell
3x32	Lig	Shared	15.0367	12.3362	1	1	1	0
3x33	Lig	Shared	6.43667	9.19615	1	1	1	0
3x36	Lig	Shared	7.76333	7.78461	1	1	1	0
5x36	Lig	mop_off	4.29	0	1	1	1	0
5x40	Lig	mop_off	9.21667	0	1	0	1	0
5x43	Lig	Shared	4.62667	4.50077	1	1	1	0
6x51	Lig	Shared	5.19667	4.61462	0	1	1	0
6x52	Lig	Shared	4.16333	3.87231	1	1	1	0
6x55	Lig	Shared	16.1667	4.36385	1	0	1	0
7x34	Lig	mop_off	5.12333	0	1	0	1	0
7x38	Lig	Shared	3.38667	5.81615	1	1	1	0
7x42	Lig	Shared	5.99	7.94462	1	1	1	0
1x39	2x57	Shared	10.9433	4.95846	1	0	2	2
1x39	7x42	mop_off	3.64	0	1	0	2	1
2x56	3x28	mop_off	4.76	0	0	0	2	2
2x57	7x42	Shared	7.42667	9.28769	1	0	2	1
2x60	7x42	Shared	8.26667	6.93769	1	1	1	1
2x63	E1x50	Shared	10.5467	7.47539	0	1	1	2
E1x49	E2	Shared	9.89	6.93462	1	0	2	1
3x25	E1x50	Shared	3.48	5.82615	1	1	2	2
E1x50	E2x50	Shared	8.27	14.5654	1	1	2	2
3x22	E2	Shared	11.6967	8.38385	1	1	2	1
3x25	E2x50	Shared	7.28	6.86	1	1	2	2
3x32	7x42	Shared	7.28333	7.96077	1	1	1	1
3x33	4x60	Shared	8.41	5.63077	1	1	1	2
3x36	6x48	Shared	6.59	5.36923	1	1	1	1
3x36	6x52	mop_off	3.50333	0	1	1	1	1
3x37	5x43	Shared	5.24	4.93923	0	0	2	1
3x40	6x44	mop_off	4.60667	0	0	0	2	2
E2	E2	Shared	44.6667	39.0054	1	1	1	1
E2	E2x51	Shared	13	5.93692	1	1	1	2
E2	E2x52	Shared	4.46333	3.55846	1	1	1	1
5x35	E2	Shared	9.28333	8.10692	1	1	2	1
5x36	E2	Shared	12.05	8.43692	1	1	1	1
5x36	5x40	Shared	5.4	6.43846	1	1	1	1
5x40	6x55	mop_off	4.55333	0	1	0	1	1
5x47	6x52	Shared	15.84	9.57308	0	1	2	1
6x44	6x48	Shared	16.0333	8.40539	1	0	2	1
6x44	7x45	mop_off	6.04	0	1	0	2	2
6x48	7x45	Shared	3.76667	9.04	1	1	1	2
6x54	7x34	Shared	7.39333	7.86615	0	0	2	1
6x54	7x37	mop_off	4.48	0	0	0	2	2
6x58	7x30	mop_off	4.97333	0	0	0	2	2
6x58	7x34	Shared	8.89333	10.7085	0	0	2	1
E3	E3	mop_off	3.38667	0	1	0	1	1
7x30	E3	Shared	7.58333	14.4385	1	0	2	1
7x34	7x35	Shared	5.29333	4.47615	1	0	1	2
7x34	7x38	Shared	6.26667	6.86692	1	0	1	1
2x60	Lig	Shared	6.25	13.4608	1	1	1	0
E2x52	Lig	mop_off	6.01333	0	1	0	1	0
E2	Lig	mop_off	19.52	0	1	1	1	0
E3	Lig	mop_off	6.13	0	1	0	1	0
6x48	7x41	Shared	3.28333	2.38077	1	1	1	2
3x29	E2x50	mop_off	3.27	0	0	1	1	2
5x44	5x47	Shared	3.21667	3.87462	0	1	2	2
3x33	5x39	mop_off	3.12333	0	1	1	1	2
E1x50	E2	mop_off	2.77667	0	1	1	2	1
4x63	E2	Shared	2.57667	3.56154	1	0	2	1
2x60	3x28	mop_off	2.38667	0	1	1	1	2
5x32	E2	Shared	2.21	2.65615	0	0	2	1
7x31	E3	mop_off	1.88	0	1	0	2	1
5x37	6x59	mop_off	1.56333	0	0	0	2	2
2x63	Lig	mop_on	0	3.80154	0	1	1	0
3x29	Lig	mop_on	0	5.13154	0	1	1	0
1x39	7x35	mop_on	0	11.3923	1	0	2	2
1x39	7x38	mop_on	0	6.78692	1	0	2	1
2x56	3x32	mop_on	0	5.33846	0	0	2	1
2x60	3x32	mop_on	0	3.61615	1	1	1	1
3x36	3x37	mop_on	0	3.63615	1	1	1	2
3x40	6x48	mop_on	0	6.59615	0	0	2	1
5x31	E2	mop_on	0	3.55923	0	1	2	1
5x44	6x52	mop_on	0	5.05077	0	1	2	1
6x48	6x52	mop_on	0	6.42846	1	1	1	1
6x51	7x37	mop_on	0	3.52308	0	1	1	2
6x54	7x30	mop_on	0	5.29	0	0	2	2
6x48	Lig	mop_on	0	3.62154	1	1	1	0
3x28	E1x50	mop_on	0	3.86692	0	0	2	2
5x39	E2	mop_on	0	3.46538	0	0	2	1
5x40	6x59	mop_on	0	3.45846	1	0	1	2
3x25	E2	mop_on	0	3.38	1	1	2	1
3x29	4x64	mop_on	0	2.74846	0	1	1	2
5x37	5x40	mop_on	0	1.4	0	0	2	1
Lig	NT	mop_on	0	0.273846	1	1	0	1

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Difference Members
	Id	Description
	mop_off	4DKL-μ-β-Funaltrexamine 8QOT-μ-Nanobody-E 7UL4-μ-Alvimopan
	mop_on	8F7R-μ-Endomorphin-Gi1/β1/γ2 8EF5-μ-Fentanyl-Gi1/β1/γ2 7SCG-μ-FH210-Gi1/β1/γ2 7T2H-μ-Lofentanil-Gi1/β1/γ2 7T2G-μ-Mitragynine Pseudoindoxyl-Gi1/β1/γ2 8EF6-μ-Morphine-Gi1/β1/γ2 8EFB-μ-Oliceridine-Gi1/β1/γ2 7U2L-μ-PubChem 163201242-Gi1/β1/γ2 8EFO-μ-PZM21-Gi1/β1/γ2 8EFL-μ-SR17018-Gi1/β1/γ2 8F7Q-μ-β-Endorphin-Gi1/β1/γ2 7U2K-μ-C6-guano-Gi1/β1/γ2 8EFQ-μ-Damgo-Gi1/β1/γ2

Network Difference
Value	mop_off	mop_on
I_min	3.28667	3.49231
Number of Linked Nodes	264	266
Number of Specific Nodes	2 (0.76%)	4 (1.50%)
Number of Shared Nodes	262 (99.24%)	262 (98.50%)
Number of Links	286	287
Number of Specific Links	106 (37.06%)	107 (37.28%)
Number of Shared Links	180 (62.94%)	180 (62.72%)
Number of Hubs	28	33
Number of Specific Hubs	8 (28.57%)	13 (39.39%)
Number of Shared Hubs	20 (71.43%)	20 (60.61%)
Average % Shared Neighbours (Jaccard)	50.36
Average % Shared Neighbours (Otsuka)	59.81
Average % Shared Neighbours (Overlap Coefficient)	69.28
Average % Shared Cliques (k3-6)	52.88
Graphlets Similarity	0.482277

Paths Difference
Value	mop_off	mop_on
Number Of Nodes in MetaPath	61	76
Specific Nodes in MetaPath	22 (36.07%)	37 (48.68%)
Shared Nodes in MetaPath	262 (99.24%)	262 (99.24%)
Number Of Links MetaPath	62	80
Specific Links in MetaPath	40 (64.52%)	58 (72.50%)
Shared Links in MetaPath	180 (62.94%)	180 (62.94%)
Number of Shortest Paths	33361	53506
Length Of Smallest Path	3	3
Average Path Length	15.1553	13.7756
Length of Longest Path	39	30
Minimum Path Strength	0.51	0.53
Average Path Strength	6.07978	5.695
Maximum Path Strength	14.99	16.0323
Minimum Path Correlation	0.706667	0.703077
Average Path Correlation	0.929468	0.920443
Maximum Path Correlation	0.99	0.99
Minimum % Of Corr. Nodes	3.22581	4
Average % Of Corr. Nodes	48.1602	44.3834
Maximum % Of Corr. Nodes	100	100
Minimum Path Hubs %	0	0
Average Path Hubs %	32.2605	39.7868
Maximum Path Hubs %	100	100

Details about the values in these tables can be found in the corresponding documentation page .

You can download a compressed (zip) file with structure(s), 3D outputs (as PyMol and VMD scripts) and numerical data files (as csv and plain text files).

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