Orange: nodes, hubs and links specific of mop_on_gp network

Green: nodes, hubs and links shared by both networks

Purple: nodes, hubs and links specific of mop_off network

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Owner: the name of the network the hub belong to or "Shared" if the corresponding hub is present in both networks.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub in the corresponding network.

Num Of Links: the number of links of the corresponding hub in the corresponding network.

ConSurf: this column reports the ConSurf conservation grades of each hub.


Index Hub Owner mop_on_gp Avg Int. Strength mop_off Avg Int. Strength mop_on_gp Num Of Links mop_off Num Of Links ConSurf
1G.HN.11 mop_on_gp00402
2G.HN.45 mop_on_gp00404
3G.S1.02 mop_on_gp84.61540405
4G.S1.06 mop_on_gp61.53850408
5G.H1.01 mop_on_gp30.76920409
6G.H1.07 mop_on_gp15.38460409
7G.S2.01 mop_on_gp46.15380409
8G.S2.04 mop_on_gp7.692310406
9G.S2.05 mop_on_gp00403
10G.S2.08 mop_on_gp84.61540405
11G.S3.01 mop_on_gp76.92310404
12G.S3.03 mop_on_gp92.30770507
13G.S3.04 mop_on_gp46.15380406
14G.S3.06 mop_on_gp92.30770605
15G.s3h2.03 mop_on_gp53.84620409
16G.H2.04 mop_on_gp76.92310509
17G.H2.06 mop_on_gp92.30770509
18G.H2.07 mop_on_gp92.30770709
19G.H2.09 mop_on_gp69.23080408
20G.h2s4.01 mop_on_gp92.30770509
21G.S4.02 mop_on_gp61.53850508
22G.S4.04 mop_on_gp84.61540409
23G.S4.05 mop_on_gp15.38460407
24G.s4h3.04 mop_on_gp84.61540708
25G.s4h3.05 mop_on_gp30.76920409
26G.s4h3.10 mop_on_gp00409
27G.H3.01 mop_on_gp30.76920409
28G.H3.09 mop_on_gp1000609
29G.H3.13 mop_on_gp53.84620405
30G.H3.15 mop_on_gp46.15380408
31G.H3.17 mop_on_gp1000605
32G.H3.18 mop_on_gp1000409
33G.S5.02 mop_on_gp15.38460406
34G.S5.03 mop_on_gp84.61540508
35G.S5.05 mop_on_gp1000609
36G.HG.03 mop_on_gp00406
37G.HG.04 mop_on_gp76.92310509
38G.hgh4.02 mop_on_gp84.61540707
39G.hgh4.05 mop_on_gp76.92310407
40G.H4.03 mop_on_gp46.15380404
41G.H4.10 mop_on_gp30.76920406
42G.H4.15 mop_on_gp61.53850508
43G.h4s6.02 mop_on_gp38.46150408
44G.S6.02 mop_on_gp1000707
45G.H5.08 mop_on_gp1000408
46G.H5.15 mop_on_gp38.46150407
47G.H5.19 mop_on_gp15.38460408
48G.H5.26 mop_on_gp69.23080505
49b.1x15 mop_on_gp15.38460407
50b.h2x1 mop_on_gp23.07690405
51b.lhb1x11 mop_on_gp38.46150404
52b.b1x3 mop_on_gp69.23080407
53b.l1x3 mop_on_gp1000709
54b.b2x1 mop_on_gp84.61540508
55b.b2x5 mop_on_gp76.92310607
56b.b3x4 mop_on_gp30.76920409
57b.l3x2 mop_on_gp23.07690509
58b.b4x2 mop_on_gp61.53850408
59b.b4x4 mop_on_gp46.15380408
60b.b4x6 mop_on_gp1000709
61b.l4x2 mop_on_gp69.23080404
62b.b5x2 mop_on_gp30.76920407
63b.b5x3 mop_on_gp1000609
64b.b5x5 mop_on_gp76.92310405
65b.b5x7 mop_on_gp1000407
66b.l5x1 mop_on_gp46.15380408
67b.l5x5 mop_on_gp1000609
68b.b6x5 mop_on_gp1000606
69b.l6x5 mop_on_gp92.30770404
70b.b7x1 mop_on_gp1000504
71b.b7x4 mop_on_gp23.07690408
72b.l7x2 mop_on_gp76.92310409
73b.b8x4 mop_on_gp1000606
74b.l8x3 mop_on_gp00403
75b.l8x5 mop_on_gp00403
76b.l8x8 mop_on_gp69.23080404
77b.l9x3 mop_on_gp1000509
78b.l9x6 mop_on_gp1000808
79b.b10x5 mop_on_gp69.23080609
80b.l10x1 mop_on_gp38.46150403
81b.b11x3 mop_on_gp46.15380405
82b.b11x4 mop_on_gp84.61540409
83b.l11x2 mop_on_gp84.61540509
84b.b12x5 mop_on_gp61.53850406
85b.b12x6 mop_on_gp1000608
86b.b12x7 mop_on_gp15.38460409
87b.b13x7 mop_on_gp92.30770507
88b.l13x3 mop_on_gp1000609
89b.l13x6 mop_on_gp69.23080409
90b.l13x7 mop_on_gp84.61540409
91b.b15x1 mop_on_gp69.23080509
92b.b15x2 mop_on_gp30.76920406
93b.b15x3 mop_on_gp69.23080409
94b.l15x1 mop_on_gp69.23080407
95b.l15x2 mop_on_gp61.53850509
96b.b16x4 mop_on_gp92.30770506
97b.b16x5 mop_on_gp53.84620505
98b.b16x6 mop_on_gp1000608
99b.b17x5 mop_on_gp76.92310507
100b.b17x7 mop_on_gp92.30770408
101b.l17x3 mop_on_gp1000709
102b.l17x6 mop_on_gp69.23080409
103b.l17x7 mop_on_gp23.07690407
104b.b18x3 mop_on_gp92.30770408
105b.l18x1 mop_on_gp1000706
106b.l18x2 mop_on_gp69.23080407
107b.l18x3 mop_on_gp53.84620405
108b.b19x2 mop_on_gp1000706
109b.b19x4 mop_on_gp84.61540508
110b.l19x2 mop_on_gp84.61540609
111b.b20x2 mop_on_gp38.46150406
112b.b20x4 mop_on_gp1000608
113b.b20x6 mop_on_gp1000606
114b.b21x1 mop_on_gp61.53850507
115b.b21x5 mop_on_gp30.76920404
116b.b21x7 mop_on_gp84.61540605
117b.l21x5 mop_on_gp23.07690404
118b.b22x5 mop_on_gp69.23080507
119b.l22x5 mop_on_gp1000509
120b.b23x6 mop_on_gp1000607
121b.l23x1 mop_on_gp46.15380406
122b.l23x2 mop_on_gp46.15380408
123b.b24x3 mop_on_gp53.84620405
124b.b24x4 mop_on_gp84.61540406
125b.b24x6 mop_on_gp69.23080408
126b.l24x2 mop_on_gp30.76920406
127b.l24x3 mop_on_gp30.76920405
128b.b25x3 mop_on_gp53.84620405
129b.l25x3 mop_on_gp1000509
130b.l25x6 mop_on_gp53.84620408
131b.b26x3 mop_on_gp92.30770406
132b.l27x1 mop_on_gp1000709
133b.l27x2 mop_on_gp53.84620409
134b.b28x3 mop_on_gp69.23080607
135b.b28x4 mop_on_gp38.46150506
136b.b28x6 mop_on_gp84.61540409
137b.b28x7 mop_on_gp46.15380409
138g.h1x5 mop_on_gp00406
139g.h1x12 mop_on_gp00506
140g.l1x4 mop_on_gp46.15380608
141g.h2x11 mop_on_gp76.92310406
142g.ctx3 mop_on_gp1000609
143g.ctx6 mop_on_gp84.61540506
144g.ctx14 mop_on_gp69.23080509
145g.ctx15 mop_on_gp53.84620409
146g.ctx16 mop_on_gp1000908
1471x35 mop_on_gp033.3333436
1481x39 mop_on_gp76.923133.3333437
1491x53 mop_on_gp69.23080419
1502x44 mop_on_gp38.46150436
1512x46 mop_on_gp61.53850519
1522x50 mop_on_gp1000539
1532x56 mop_on_gp00436
1542x64 mop_on_gp23.07690435
1553x32 mop_on_gp38.46150425
1563x35 mop_on_gp61.53850438
1573x37 mop_on_gp76.923133.3333536
1583x38 mop_on_gp76.92310437
1593x50 mop_on_gp46.153866.6667439
1605x44 mop_on_gp53.84620436
1615x50 mop_on_gp23.07690438
1626x52 mop_on_gp76.92310437
1637x35 mop_on_gp69.23080424
164Lig Shared10010016180
1652x42 Shared10066.6667657
1662x57 Shared76.92310447
167E1x50 Shared10066.6667868
168E1x52 Shared92.307766.6667556
1693x34 Shared84.615466.6667645
1703x51 Shared92.307766.6667458
171I2x57 Shared10033.3333647
1724x50 Shared84.615466.6667449
173E2 Shared10010014123
1745x47 Shared84.615466.6667548
1755x58 Shared10033.3333559
176I3 Shared84.615433.33331053
1776x44 Shared76.9231100559
1786x48 Shared10066.6667748
1796x49 Shared53.84620445
1807x34 Shared92.307766.6667454
1817x42 Shared69.230866.6667457
1827x45 Shared69.230833.3333469
1837x49 Shared84.61540549
1847x53 Shared10066.6667659
1858x50 Shared84.615466.6667648
1861x36 mop_off00345
1871x42 mop_off00147
1881x50 mop_off46.15380349
1891x60 mop_off033.3333354
1906x32 mop_off033.3333347
191E3 mop_off38.46150152
   
Orange: nodes, hubs and links specific of mop_on_gp network

Green: nodes, hubs and links shared by both networks

Purple: nodes, hubs and links specific of mop_off network

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Owner: the name of the network the link belong to or "Shared" if the corresponding link is present in both networks.

Recurrence: the relative Recurrence in the filtered pool of shortest paths.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.


Index Node1 Node2 Owner mop_on_gp Recurrence mop_off Recurrence mop_on_gp Hub1? mop_off Hub1? mop_on_gp Hub2? mop_off Hub2? ConSurf1 ConSurf2
1b.b3x2 b.b4x6 mop_on_gp18.760NoNoYesNo59
2b.b2x5 b.b3x2 mop_on_gp18.98870YesNoNoNo75
3b.b2x3 b.b2x5 mop_on_gp24.21660NoNoYesNo67
4b.b26x2 b.b2x3 mop_on_gp24.44860NoNoNoNo76
5b.b26x1 b.b26x2 mop_on_gp24.71150NoNoNoNo97
6b.b26x1 b.l27x1 mop_on_gp25.00630NoNoYesNo99
7G.H3.17 b.l27x1 mop_on_gp17.33080YesNoYesNo59
8G.H3.15 G.H3.17 mop_on_gp42.15010YesNoYesNo85
9G.H2.08 G.H3.15 mop_on_gp34.73330NoNoYesNo88
10G.H2.04 G.H2.08 mop_on_gp35.11880YesNoNoNo98
11G.H2.04 G.H3.08 mop_on_gp81.76460YesNoNoNo99
12G.H3.08 G.S4.04 mop_on_gp81.82110NoNoYesNo99
13G.S4.04 G.s1h1.01 mop_on_gp1000YesNoNoNo99
14G.H1.01 G.s1h1.01 mop_on_gp99.96650YesNoNoNo99
15G.H1.01 G.S1.06 mop_on_gp99.61890YesNoYesNo98
16G.S1.06 G.S4.03 mop_on_gp99.59490YesNoNoNo87
17G.S1.04 G.S4.03 mop_on_gp16.28340NoNoNoNo77
18G.S1.04 G.S3.03 mop_on_gp16.18320NoNoYesNo77
19G.H5.11 G.S3.03 mop_on_gp14.18210NoNoYesNo87
20G.H5.11 G.H5.15 mop_on_gp14.24040NoNoYesNo87
21G.H5.15 G.H5.19 mop_on_gp13.13320YesNoYesNo78
22G.H5.19 I2x57 mop_on_gp12.80260YesNoYesYes87
23G.H3.01 G.s4h3.06 mop_on_gp15.84880YesNoNoNo98
24G.s4h3.05 G.s4h3.06 mop_on_gp17.18520YesNoNoNo98
25G.s4h3.04 G.s4h3.05 mop_on_gp25.17930YesNoYesNo89
26G.HG.04 G.s4h3.01 mop_on_gp12.59740YesNoNoNo97
27G.H4.11 G.s4h3.01 mop_on_gp12.8730NoNoNoNo77
28G.H4.11 G.H4.15 mop_on_gp13.19360NoNoYesNo78
29G.H3.09 G.H4.15 mop_on_gp23.37710YesNoYesNo98
30G.HG.15 G.s4h3.04 mop_on_gp14.62520NoNoYesNo78
31G.HG.15 G.hgh4.02 mop_on_gp17.61310NoNoYesNo77
32G.H3.06 G.hgh4.02 mop_on_gp40.15140NoNoYesNo67
33G.H3.06 G.H4.15 mop_on_gp26.05420NoNoYesNo68
34G.hgh4.01 G.s4h3.04 mop_on_gp14.58780NoNoYesNo68
35G.hgh4.01 G.hgh4.02 mop_on_gp15.08840NoNoYesNo67
36G.H3.06 G.h4s6.01 mop_on_gp14.61110NoNoNoNo64
37G.H3.09 G.h4s6.01 mop_on_gp15.28410YesNoNoNo94
38G.S4.03 G.S5.03 mop_on_gp84.08540NoNoYesNo78
39G.H2.04 G.H2.07 mop_on_gp64.23930YesNoYesNo99
40G.H2.07 b.l9x6 mop_on_gp68.04480YesNoYesNo98
41b.l11x1 b.l9x6 mop_on_gp30.64980NoNoYesNo98
42b.b11x6 b.l11x1 mop_on_gp34.56870NoNoNoNo99
43G.H2.06 b.l9x6 mop_on_gp46.76360YesNoYesNo98
44G.H2.06 b.l17x6 mop_on_gp45.9360YesNoYesNo99
45G.S4.04 G.S4.06 mop_on_gp18.73520YesNoNoNo97
46G.HG.07 G.s4h3.04 mop_on_gp10.68850NoNoYesNo98
47G.H3.01 G.s4h3.08 mop_on_gp10.50050YesNoNoNo98
48G.S5.03 G.S6.02 mop_on_gp80.88550YesNoYesNo87
49G.S6.02 I3 mop_on_gp80.68430YesNoYesYes73
50G.H5.26 I3 mop_on_gp29.82760YesNoYesYes53
51G.H5.20 G.H5.26 mop_on_gp28.1140NoNoYesNo95
525x65 G.H5.20 mop_on_gp27.38670NoNoNoNo89
53G.H5.20 G.H5.25 mop_on_gp55.25150NoNoNoNo97
543x50 G.H5.25 mop_on_gp54.78880YesNoNoNo97
55b.l17x5 b.l17x6 mop_on_gp49.66870NoNoYesNo69
56b.l17x5 b.l19x2 mop_on_gp49.49790NoNoYesNo69
57b.b20x4 b.l19x2 mop_on_gp18.63070YesNoYesNo89
58b.b20x4 b.b20x6 mop_on_gp17.93140YesNoYesNo86
59b.b17x7 b.b20x6 mop_on_gp23.58390YesNoYesNo86
60b.b17x7 b.b21x1 mop_on_gp18.22990YesNoYesNo87
61b.1x19 b.b21x1 mop_on_gp14.35890NoNoYesNo67
62b.1x15 b.1x19 mop_on_gp13.88850YesNoNoNo76
63b.1x15 g.h1x11 mop_on_gp10.9140YesNoNoNo79
64b.l17x3 b.l19x2 mop_on_gp28.95280YesNoYesNo99
65b.b20x6 b.l17x3 mop_on_gp17.93090YesNoYesNo69
66b.b10x2 b.b10x4 mop_on_gp10.26080NoNoNoNo66
67b.b10x2 b.b6x2 mop_on_gp20.46370NoNoNoNo68
68b.b10x3 b.b6x2 mop_on_gp20.66720NoNoNoNo88
69b.b10x3 b.b11x2 mop_on_gp10.42680NoNoNoNo87
70b.b10x3 b.b11x4 mop_on_gp29.88070NoNoYesNo89
71b.b11x4 b.l9x3 mop_on_gp29.89530YesNoYesNo99
72b.b11x6 b.l9x3 mop_on_gp32.0840NoNoYesNo99
73b.b10x2 b.b14x3 mop_on_gp10.60370NoNoNoNo65
74b.b19x4 b.l17x3 mop_on_gp10.09220YesNoYesNo89
75b.b19x2 b.b20x6 mop_on_gp11.82620YesNoYesNo66
76b.b15x2 b.b19x2 mop_on_gp10.38670YesNoYesNo66
77b.b16x5 b.b17x4 mop_on_gp11.12710YesNoNoNo55
78b.l23x1 b.l25x6 mop_on_gp13.17140YesNoYesNo68
79b.l21x7 b.l23x1 mop_on_gp13.06920NoNoYesNo56
80b.l21x7 b.l23x2 mop_on_gp12.8790NoNoYesNo58
81b.b23x6 b.l23x2 mop_on_gp10.92180YesNoYesNo78
82b.b22x1 b.l25x6 mop_on_gp12.05260NoNoYesNo88
83b.b22x2 b.b26x3 mop_on_gp11.96430NoNoYesNo86
843x50 7x53 mop_on_gp55.31030YesNoYesYes99
857x49 7x53 mop_on_gp48.48215.9873YesYesYesYes99
866x48 Lig mop_on_gp54.51560YesYesYesYes80
873x47 5x58 mop_on_gp22.39830.193529NoNoYesYes99
883x47 5x54 mop_on_gp22.38291.37889NoNoNoNo98
895x54 6x44 mop_on_gp22.26240NoNoYesYes89
903x33 Lig mop_on_gp11.56184.33626NoNoYesYes40
917x38 Lig mop_on_gp17.65211.37285NoNoYesYes50
922x63 Lig mop_on_gp15.50340NoNoYesYes40
932x63 E1x50 mop_on_gp15.06151.58452NoNoYesYes48
94E2 E2x52 mop_on_gp10.22470.133051YesYesNoNo34
953x33 E2x52 mop_on_gp10.6620NoNoNoNo44
96b.b22x1 b.b22x2 mop_on_gp12.14740NoNoNoNo88
97G.H3.09 G.S4.04 mop_on_gp32.51880YesNoYesNo99
98G.H4.15 G.S4.06 mop_on_gp18.40930YesNoNoNo87
99G.H3.17 b.l25x6 mop_on_gp23.94620YesNoYesNo58
1005x65 I3 Shared50.679610.88NoNoYesYes83
1017x45 7x49 Shared44.65620.8406YesYesYesYes99
1026x48 7x45 Shared43.717814.3211YesYesYesYes89
1033x54 5x65 Shared23.223712.3677NoNoNoNo88
1043x54 5x61 Shared23.120515.0045NoNoNoNo88
1055x58 5x61 Shared23.020940.6592YesYesNoNo98
1066x44 6x48 Shared21.451386.0962YesYesYesYes98
107E1x50 E2 Shared10.364417.7926YesYesYesYes83
1082x58 2x61 mop_off010.9162NoNoNoNo86
1091x43 2x58 mop_off0.45860112.4282NoNoNoNo68
1101x43 2x57 mop_off4.5760813.928NoNoYesYes67
1112x57 7x42 mop_off5.5384126.8521YesYesYesYes77
1121x42 2x57 mop_off0.45860113.9159NoYesYesYes77
1132x56 3x28 mop_off0.69979611.8778YesNoNoNo65
1142x60 3x28 mop_off013.0813NoNoNoNo65
1152x60 Lig mop_off0.45136713.3293NoNoYesYes60
1162x50 7x49 mop_off4.332812.3314YesNoYesYes99
1173x36 6x48 mop_off0.527269100NoNoYesYes78
1183x36 Lig mop_off0.58048682.2558NoNoYesYes70
1191x60 8x53 mop_off026.4469NoYesNoNo46
1208x53 I1x50 mop_off029.1684NoNoNoNo67
1212x40 I1x50 mop_off029.1261NoNoNoNo87
1222x37 2x40 mop_off3.5584545.4732NoNoNoNo78
1232x37 2x39 mop_off046.6586NoNoNoNo78
1242x39 6x33 mop_off047.8077NoNoNoNo88
1253x50 6x33 mop_off060.5624YesNoNoNo98
1263x50 6x37 mop_off062.4493YesNoNoNo98
1273x46 6x37 mop_off063.3263NoNoNoNo98
1282x42 3x46 mop_off1.2074564.3302YesYesNoNo79
1292x42 4x42 mop_off0.43346471.5331YesYesNoNo77
1302x41 4x42 mop_off072.404NoNoNoNo57
1312x41 4x46 mop_off0.42880574.1095NoNoNoNo57
1322x45 4x46 mop_off3.1740474.9441NoNoNoNo97
1332x45 3x42 mop_off0.56368771.1823NoNoNoNo98
1343x42 4x49 mop_off071.8718NoNoNoNo87
1353x41 4x49 mop_off1.9421986.0115NoNoNoNo57
1363x40 3x41 mop_off087.2815NoNoNoNo75
1373x40 6x44 mop_off0.16308690.2449NoNoYesYes79
1382x40 8x50 mop_off3.0541115.1376NoNoYesYes88
1393x38 4x49 mop_off013.5047YesNoNoNo77
1403x38 4x50 mop_off0.48778512.1379YesNoYesYes79
141E2 Lig mop_off038.7179YesYesYesYes30
1427x34 Lig mop_off013.2991YesYesYesYes40
1433x34 4x50 mop_off2.3036710.8316YesYesYesYes59
1443x43 6x44 mop_off049.0112NoNoYesYes89
1453x43 6x41 mop_off047.8621NoNoNoNo88
1465x54 6x41 mop_off046.7009NoNoNoNo88
1475x54 5x58 mop_off044.1427NoNoYesYes89
1483x51 5x61 mop_off026.1687YesYesNoNo88
1491x60 I1x48 mop_off013.8071NoYesNoNo46
150I1x48 I1x51 mop_off012.3193NoNoNoNo67
1515x35 E2 mop_off6.2838210.3538NoNoYesYes13
1526x52 Lig mop_off0.49244510.5171YesNoYesYes70
1535x47 6x52 mop_off6.7832526.6646YesYesYesNo87
1545x44 5x47 mop_off0.0062536612.3314YesNoYesYes68
1555x47 6x49 mop_off4.0795910.8316YesYesYesYes85
1566x29 6x33 mop_off016.5528NoNoNoNo58
1576x29 6x32 mop_off0.54014415.0892NoNoNoYes57
1586x32 8x48 mop_off0.54161610.6259NoYesNoNo75
1597x42 Lig mop_off5.7993531.2005YesYesYesYes70
1603x36 6x52 mop_off017.345NoNoYesNo77
1616x44 7x45 mop_off0.13684515.9298YesYesYesYes99

Here, those paths that begin and end at given residue pair(s) or that pass through a residue are used to generate a novel metapath. Such a path filtering is particularly recommended if some information on allosteric residues is available. The selection syntax for a residue pair ("Pairs") is C:C:c534,A:A:?600 (the lower-case "c" stands for cytosine and "?" indicates any non standard amino acid or nucleotide residue). Selection of more than one apical residue pair has the following syntax: C:C:c534,A:A:?600,C:C:c534,A:A:E41. Only one residue can be selected as a tail ("Tail"). For midway residue(s), each residue must be separated by a comma as well e.g. A:A:?600,A:A:E41.

Midway



Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.


2D representation of the interactions of this orthosteric/allosteric ligand.


Node1Node2OwnerNet1LinkStrengthNet2LinkStrengthComm1Comm2Node1ShellNode2Shell
3x32LigShared15.036712.33621210
3x33LigShared6.436679.196151210
3x36LigShared7.763337.784611210
5x36Ligmop_off4.2901210
5x40Ligmop_off9.2166701010
5x43LigShared4.626674.500771210
6x51LigShared5.196674.614620210
6x52LigShared4.163333.872311210
6x55LigShared16.16674.363851010
7x34Ligmop_off5.1233301010
7x38LigShared3.386675.816151210
7x42LigShared5.997.944621210
1x392x57Shared10.94334.958461022
1x397x42mop_off3.6401021
2x563x28Shared4.762.686150022
2x577x42Shared7.426679.287691021
2x607x42Shared8.266676.937691211
2x63E1x50Shared10.54677.475390212
E1x49E2Shared9.896.934621021
3x25E1x50Shared3.485.826151222
E1x50E2x50Shared8.2714.56541222
3x22E2Shared11.69678.383851221
3x25E2x50Shared7.286.861222
3x327x42Shared7.283337.960771211
3x334x60Shared8.415.630771212
3x366x48Shared6.595.369231211
3x366x52mop_off3.5033301211
3x375x43Shared5.244.939230021
3x406x44Shared4.606673.188460222
E2E2Shared44.666739.00541211
E2E2x51Shared135.936921212
E2E2x52Shared4.463333.558461211
5x35E2Shared9.283338.106921221
5x36E2Shared12.058.436921211
5x365x40Shared5.46.438461211
5x406x55mop_off4.5533301011
5x476x52Shared15.849.573080221
6x446x48Shared16.03338.405391221
6x447x45Shared6.043.251541222
6x487x45Shared3.766679.041212
6x547x34Shared7.393337.866150021
6x547x37mop_off4.4800022
6x587x30mop_off4.9733300022
6x587x34Shared8.8933310.70850021
E3E3mop_off3.3866701011
7x30E3Shared7.5833314.43851021
7x347x35Shared5.293334.476151012
7x347x38Shared6.266676.866921011
2x60LigShared6.2513.46081210
E2x52Ligmop_off6.0133301210
E2Ligmop_off19.5201210
E3Ligmop_off6.1301010
6x487x41Shared3.283332.380771212
3x29E2x50Shared3.273.396150212
5x445x47Shared3.216673.874620222
3x335x39mop_off3.1233301212
E1x50E2Shared2.776672.926921221
4x63E2Shared2.576673.561541021
2x603x28mop_off2.3866701212
5x32E2Shared2.212.656150021
7x31E3mop_off1.8801021
5x376x59mop_off1.5633300022
2x63Ligmop_on_gp03.801540210
3x29Ligmop_on_gp05.131540210
1x397x35mop_on_gp011.39231022
1x397x38mop_on_gp06.786921021
2x563x32mop_on_gp05.338460021
2x603x32mop_on_gp03.616151211
3x25E2mop_on_gp03.381221
3x294x64mop_on_gp02.748460212
3x33E2x52mop_on_gp02.795381211
3x363x37mop_on_gp03.636151212
3x406x48mop_on_gp06.596150221
4x60E2x52mop_on_gp03.209230221
5x39E2mop_on_gp03.465380021
5x31E2mop_on_gp03.559230221
5x315x35mop_on_gp02.909230222
5x406x59mop_on_gp03.458461012
5x446x52mop_on_gp05.050770221
6x486x52mop_on_gp06.428461211
6x517x37mop_on_gp03.523080212
6x547x30mop_on_gp05.290022
6x48Ligmop_on_gp03.621541210
3x28E1x50mop_on_gp03.866920222
5x375x40mop_on_gp01.40021
LigNTmop_on_gp00.2738461201

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Difference Members
Id Description
mop_on_gp 8F7R-μ-Endomorphin-Gi1/β1/γ2
8EF5-μ-Fentanyl-Gi1/β1/γ2
7SCG-μ-FH210-Gi1/β1/γ2
7T2H-μ-Lofentanil-Gi1/β1/γ2
7T2G-μ-Mitragynine Pseudoindoxyl-Gi1/β1/γ2
8EF6-μ-Morphine-Gi1/β1/γ2
8EFB-μ-Oliceridine-Gi1/β1/γ2
7U2L-μ-PubChem 163201242-Gi1/β1/γ2
8EFO-μ-PZM21-Gi1/β1/γ2
8EFL-μ-SR17018-Gi1/β1/γ2
8F7Q-μ-β-Endorphin-Gi1/β1/γ2
7U2K-μ-C6-guano-Gi1/β1/γ2
8EFQ-μ-Damgo-Gi1/β1/γ2
mop_off 4DKL-μ-β-Funaltrexamine
8QOT-μ-Nanobody-E
7UL4-μ-Alvimopan
Network Difference
Value mop_on_gp mop_off
Imin 2.65 3.28667
Number of Linked Nodes 878 264
Number of Specific Nodes 616 (70.16%) 2  (0.76%)
Number of Shared Nodes 262 (29.84%) 262  (99.24%)
Number of Links 1094 286
Number of Specific Links 911 (83.27%) 103  (36.01%)
Number of Shared Links 183 (16.73%) 183  (63.99%)
Number of Hubs 185 28
Number of Specific Hubs 163 (88.11%) 6  (21.43%)
Number of Shared Hubs 22 (11.89%) 22  (78.57%)
Average % Shared Neighbours (Jaccard) 14.65
Average % Shared Neighbours (Otsuka) 17.69
Average % Shared Neighbours (Overlap Coefficient) 20.71
Average % Shared Cliques (k3-6) 50.65
Graphlets Similarity 0.547894
Paths Difference
Value mop_on_gp mop_off
Number Of Nodes in MetaPath 102 61
Specific Nodes in MetaPath 88 (86.27%) 47  (77.05%)
Shared Nodes in MetaPath 262 (29.84%) 262  (29.84%)
Number Of Links MetaPath 107 62
Specific Links in MetaPath 99 (92.52%) 54  (87.10%)
Shared Links in MetaPath 183 (16.73%) 183  (16.73%)
Number of Shortest Paths 1459913 33361
Length Of Smallest Path 3 3
Average Path Length 25.6173 15.1553
Length of Longest Path 52 39
Minimum Path Strength 0.303462 0.51
Average Path Strength 5.12024 6.07978
Maximum Path Strength 21.1346 14.99
Minimum Path Correlation 0.702308 0.706667
Average Path Correlation 0.978196 0.929468
Maximum Path Correlation 1 0.99
Minimum % Of Corr. Nodes 2.32558 3.22581
Average % Of Corr. Nodes 43.2876 48.1602
Maximum % Of Corr. Nodes 100 100
Minimum Path Hubs % 0 0
Average Path Hubs % 57.3027 32.2605
Maximum Path Hubs % 100 100

Details about the values in these tables can be found in the corresponding documentation page .

You can download a compressed (zip) file with structure(s), 3D outputs (as PyMol and VMD scripts) and numerical data files (as csv and plain text files).

Download mop_off_on_gp.zip<



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