Orange: nodes, hubs and links specific of neurotensin_on_gp network

Green: nodes, hubs and links shared by both networks

Purple: nodes, hubs and links specific of neurotensin_off network

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Owner: the name of the network the hub belong to or "Shared" if the corresponding hub is present in both networks.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub in the corresponding network.

Num Of Links: the number of links of the corresponding hub in the corresponding network.

ConSurf: this column reports the ConSurf conservation grades of each hub.


Index Hub Owner neurotensin_on_gp Avg Int. Strength neurotensin_off Avg Int. Strength neurotensin_on_gp Num Of Links neurotensin_off Num Of Links ConSurf
1G.S1.02 neurotensin_on_gp4.631250405
2G.S1.06 neurotensin_on_gp4.7250408
3G.S2.06 neurotensin_on_gp7.96250409
4G.S2.08 neurotensin_on_gp7.2850505
5G.S3.03 neurotensin_on_gp6.198330607
6G.S3.06 neurotensin_on_gp9.581250405
7G.s3h2.03 neurotensin_on_gp4.41250409
8G.H2.06 neurotensin_on_gp8.1510509
9G.H2.07 neurotensin_on_gp5.387140709
10G.h2s4.01 neurotensin_on_gp6.056430709
11G.S4.03 neurotensin_on_gp4.598750407
12G.S4.06 neurotensin_on_gp5.07250407
13G.s4h3.04 neurotensin_on_gp7.0240508
14G.H3.01 neurotensin_on_gp8.518750409
15G.H3.09 neurotensin_on_gp7.470710709
16G.H3.17 neurotensin_on_gp7.040505
17G.H3.18 neurotensin_on_gp5.823750409
18G.S5.03 neurotensin_on_gp4.241250408
19G.S5.04 neurotensin_on_gp4.621250409
20G.S5.05 neurotensin_on_gp4.668330609
21G.S5.06 neurotensin_on_gp5.893750408
22G.S5.07 neurotensin_on_gp3.516250409
23G.HG.07 neurotensin_on_gp8.251250409
24G.hgh4.02 neurotensin_on_gp5.810830607
25G.hgh4.05 neurotensin_on_gp7.9810507
26G.H4.05 neurotensin_on_gp4.83750404
27G.H4.10 neurotensin_on_gp9.703750406
28G.H4.15 neurotensin_on_gp5.7670508
29G.h4s6.10 neurotensin_on_gp3.648750403
30G.S6.02 neurotensin_on_gp8.0770507
31G.s6h5.01 neurotensin_on_gp5.01250409
32G.s6h5.02 neurotensin_on_gp3.3820507
33G.H5.08 neurotensin_on_gp6.4320508
34G.H5.13 neurotensin_on_gp8.380408
35G.H5.23 neurotensin_on_gp3.671250404
36G.H5.25 neurotensin_on_gp3.97250407
37b.1x11 neurotensin_on_gp1.05250408
38b.lh12x2 neurotensin_on_gp3.216250408
39b.lhb1x3 neurotensin_on_gp2.9750602
40b.lhb1x6 neurotensin_on_gp4.9950403
41b.b1x6 neurotensin_on_gp7.70750409
42b.l1x3 neurotensin_on_gp7.537140709
43b.b2x1 neurotensin_on_gp7.0070508
44b.b2x5 neurotensin_on_gp5.540607
45b.b3x4 neurotensin_on_gp5.70250409
46b.l3x2 neurotensin_on_gp4.171670609
47b.b4x4 neurotensin_on_gp7.3620508
48b.b4x6 neurotensin_on_gp8.995710709
49b.l4x2 neurotensin_on_gp8.22250404
50b.b5x2 neurotensin_on_gp7.208750407
51b.b5x3 neurotensin_on_gp6.1470509
52b.b5x7 neurotensin_on_gp7.231250407
53b.l5x1 neurotensin_on_gp4.31750408
54b.l5x5 neurotensin_on_gp7.005710709
55b.b6x5 neurotensin_on_gp3.968330606
56b.l6x5 neurotensin_on_gp6.0960504
57b.b7x1 neurotensin_on_gp6.3170504
58b.l7x2 neurotensin_on_gp4.5920509
59b.b8x4 neurotensin_on_gp5.4080506
60b.l8x5 neurotensin_on_gp4.961250403
61b.b9x2 neurotensin_on_gp2.8850405
62b.l9x3 neurotensin_on_gp5.50609
63b.l9x6 neurotensin_on_gp5.521250808
64b.l9x7 neurotensin_on_gp3.626250407
65b.b10x3 neurotensin_on_gp4.061250408
66b.b10x5 neurotensin_on_gp4.4990509
67b.l10x4 neurotensin_on_gp3.998750403
68b.b11x4 neurotensin_on_gp3.8350409
69b.b11x6 neurotensin_on_gp4.89750409
70b.l11x2 neurotensin_on_gp5.80409
71b.b12x6 neurotensin_on_gp11.33250408
72b.b13x3 neurotensin_on_gp6.926250404
73b.b13x7 neurotensin_on_gp7.5060507
74b.l13x3 neurotensin_on_gp6.45750609
75b.l13x6 neurotensin_on_gp5.308750409
76b.b14x1 neurotensin_on_gp5.80508
77b.b14x3 neurotensin_on_gp5.986250405
78b.b14x5 neurotensin_on_gp4.1620505
79b.b15x1 neurotensin_on_gp6.1240509
80b.l15x1 neurotensin_on_gp3.7780507
81b.l15x2 neurotensin_on_gp4.848750409
82b.b16x4 neurotensin_on_gp10.4150406
83b.b16x5 neurotensin_on_gp4.648750405
84b.b16x6 neurotensin_on_gp8.191670608
85b.b17x4 neurotensin_on_gp4.1420505
86b.b17x5 neurotensin_on_gp6.70407
87b.b17x7 neurotensin_on_gp7.233750408
88b.l17x3 neurotensin_on_gp7.885830609
89b.l17x6 neurotensin_on_gp7.2910509
90b.b18x3 neurotensin_on_gp4.638750408
91b.b18x5 neurotensin_on_gp5.76750405
92b.l18x1 neurotensin_on_gp5.7250806
93b.l18x3 neurotensin_on_gp5.87250405
94b.b19x2 neurotensin_on_gp6.27750606
95b.b19x4 neurotensin_on_gp4.6540508
96b.b19x6 neurotensin_on_gp6.580409
97b.l19x1 neurotensin_on_gp6.13250409
98b.l19x2 neurotensin_on_gp5.6770509
99b.b20x2 neurotensin_on_gp6.02250406
100b.b20x4 neurotensin_on_gp13.7740508
101b.b20x6 neurotensin_on_gp7.7920506
102b.l20x2 neurotensin_on_gp6.75750409
103b.l20x3 neurotensin_on_gp1.7950407
104b.b21x1 neurotensin_on_gp6.4850407
105b.b21x3 neurotensin_on_gp7.963750406
106b.b21x7 neurotensin_on_gp5.689170605
107b.b22x5 neurotensin_on_gp6.931250407
108b.l22x5 neurotensin_on_gp5.570709
109b.b23x6 neurotensin_on_gp7.385830607
110b.l23x1 neurotensin_on_gp9.120406
111b.b24x4 neurotensin_on_gp8.660406
112b.b24x6 neurotensin_on_gp7.681250408
113b.l24x2 neurotensin_on_gp5.186250406
114b.l24x3 neurotensin_on_gp6.01250405
115b.l25x3 neurotensin_on_gp10.56620409
116b.l25x6 neurotensin_on_gp13.06130408
117b.l26x5 neurotensin_on_gp4.076250405
118b.l27x1 neurotensin_on_gp12.68670609
119b.l27x2 neurotensin_on_gp8.0350409
120b.b28x3 neurotensin_on_gp5.03750407
121b.b28x4 neurotensin_on_gp5.3660506
122b.b28x6 neurotensin_on_gp11.05880409
123g.ctx3 neurotensin_on_gp4.28750409
124g.ctx9 neurotensin_on_gp3.75250606
125NT neurotensin_on_gp9.7462501203
126I1 neurotensin_on_gp3.410405
1272x38 neurotensin_on_gp6.533754.23417
1282x42 neurotensin_on_gp6.5539.915528
1292x50 neurotensin_on_gp5.812510.07439
1302x64 neurotensin_on_gp5.547.22414
1313x29 neurotensin_on_gp6.6429.09333534
1323x32 neurotensin_on_gp5.5711.71537
133I2x51 neurotensin_on_gp3.643570707
1344x39 neurotensin_on_gp6.728755.39333433
1354x59 neurotensin_on_gp2.5853.04333435
136I3 neurotensin_on_gp9.812860705
1376x26 neurotensin_on_gp5.128754.59424
1386x37 neurotensin_on_gp4.318754438
1396x38 neurotensin_on_gp2.19257.285425
1406x44 neurotensin_on_gp5.391256.36333439
1416x51 neurotensin_on_gp7.95756.69426
142E3 neurotensin_on_gp14.01758.65667632
1437x31 neurotensin_on_gp11.29374.92424
1447x33 neurotensin_on_gp3.2246.325524
1457x34 neurotensin_on_gp8.70110.3833534
146H.HA.14 neurotensin_on_gp2.691250400
147H.HA.19 neurotensin_on_gp2.54250400
148H.HA.20 neurotensin_on_gp2.328750400
149H.HA.26 neurotensin_on_gp2.423750400
150H.HB.02 neurotensin_on_gp3.463750400
151H.hbhc.13 neurotensin_on_gp2.31750400
152H.HC.03 neurotensin_on_gp2.5880500
153H.HC.11 neurotensin_on_gp5.0410500
154H.HD.07 neurotensin_on_gp2.616250400
155H.hdhe.01 neurotensin_on_gp3.081250400
156H.HE.04 neurotensin_on_gp6.563750400
157H.HE.05 neurotensin_on_gp3.6250400
158H.hehf.04 neurotensin_on_gp5.196250400
159H.HF.03 neurotensin_on_gp4.653750400
160g.h3x13 neurotensin_on_gp3.333750400
161Lig Shared11.1810.8651680
1621x39 Shared3.6745.19714577
1631x50 Shared4.76256.8625449
1642x57 Shared4.876257.745448
1652x60 Shared5.454175.904656
1662x63 Shared4.938.865445
167E1x50 Shared8.0529.2925548
1683x28 Shared6.247510.27446
1693x30 Shared4.0984.1575546
1703x37 Shared10.11258.5725447
1714x50 Shared4.1164.015549
172E2 Shared21.881813.07441193
1735x47 Shared3.7659.0375448
1745x58 Shared4.6256.6075449
1756x48 Shared6.3757.6925548
1766x54 Shared7.804178.34665
1776x55 Shared6.886677.025646
1787x30 Shared7.9178.1975544
1797x42 Shared5.60311.53547
1808x50 Shared4.86257.42458
1818x54 Shared6.19759.61657
1821x52 neurotensin_off3.08755.7225246
1831x56 neurotensin_off4.4454.318357
1842x41 neurotensin_off5.696.12245
1852x49 neurotensin_off4.3454.262258
1862x62 neurotensin_off5.45755.8275245
1872x66 neurotensin_off4.80258.5725245
188E1x52 neurotensin_off3.668336.666357
1893x49 neurotensin_off6.563337.9675348
1903x50 neurotensin_off6.496676.922359
1913x51 neurotensin_off6.028336.686358
1923x52 neurotensin_off2.416673.9175344
1933x55 neurotensin_off5.16754.3247
1943x56 neurotensin_off3.43753.8625246
1954x49 neurotensin_off2.95253.45247
1964x64 neurotensin_off3.974.565145
1975x461 neurotensin_off7.634.6625146
1986x57 neurotensin_off2.125.41144
1996x59 neurotensin_off4.485.35243
2007x41 neurotensin_off5.98258.83247
2017x49 neurotensin_off7.82254.212259
2027x50 neurotensin_off4.134.335349
2037x53 neurotensin_off10.26259.3249
2048x57 neurotensin_off1.443.9125245
   
Orange: nodes, hubs and links specific of neurotensin_on_gp network

Green: nodes, hubs and links shared by both networks

Purple: nodes, hubs and links specific of neurotensin_off network

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Owner: the name of the network the link belong to or "Shared" if the corresponding link is present in both networks.

Recurrence: the relative Recurrence in the filtered pool of shortest paths.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.


Index Node1 Node2 Owner neurotensin_on_gp Recurrence neurotensin_off Recurrence neurotensin_on_gp Hub1? neurotensin_off Hub1? neurotensin_on_gp Hub2? neurotensin_off Hub2? ConSurf1 ConSurf2
1b.b1x4 g.ctx9 neurotensin_on_gp19.79040NoNoYesNo76
2g.ctx14 g.ctx9 neurotensin_on_gp24.36670NoNoYesNo96
3b.b28x7 g.ctx14 neurotensin_on_gp24.56150NoNoNoNo99
4b.b28x7 b.lhb1x11 neurotensin_on_gp25.1470NoNoNoNo94
5b.lhb1x11 b.lhb1x9 neurotensin_on_gp25.44630NoNoNoNo43
6b.lhb1x6 b.lhb1x9 neurotensin_on_gp25.84510YesNoNoNo33
7b.l22x5 b.lhb1x6 neurotensin_on_gp26.20650YesNoYesNo93
8b.l22x5 b.l24x2 neurotensin_on_gp34.77030YesNoYesNo96
9b.h2x5 b.l24x2 neurotensin_on_gp35.20440NoNoYesNo56
10b.h2x1 b.h2x5 neurotensin_on_gp36.09190NoNoNoNo55
11b.b21x5 b.h2x1 neurotensin_on_gp37.64650NoNoNoNo45
12b.b21x5 b.b21x7 neurotensin_on_gp38.09730NoNoYesNo45
13b.b21x7 b.b24x6 neurotensin_on_gp39.22480YesNoYesNo58
14b.b23x6 b.b24x6 neurotensin_on_gp40.13950YesNoYesNo78
15b.b23x6 b.l23x2 neurotensin_on_gp42.53160YesNoNoNo78
16b.l21x7 b.l23x2 neurotensin_on_gp43.2360NoNoNoNo58
17b.l21x7 b.l23x1 neurotensin_on_gp43.47160NoNoYesNo56
18b.l23x1 b.l25x6 neurotensin_on_gp43.93610YesNoYesNo68
19b.l25x6 b.l27x1 neurotensin_on_gp39.52370YesNoYesNo89
20b.b2x1 b.l27x1 neurotensin_on_gp40.41290YesNoYesNo89
21G.H2.10 b.b2x1 neurotensin_on_gp34.76380NoNoYesNo78
22G.S1.05 G.S1.07 neurotensin_on_gp84.22190NoNoNoNo99
23G.S1.07 G.S4.04 neurotensin_on_gp84.00450NoNoNoNo99
24G.H3.09 G.S4.04 neurotensin_on_gp83.78680YesNoNoNo99
25G.H3.09 G.S5.04 neurotensin_on_gp70.27160YesNoYesNo99
26G.S5.04 G.S5.06 neurotensin_on_gp70.20210YesNoYesNo98
27G.S5.06 G.S6.05 neurotensin_on_gp67.91840YesNoNoNo84
28G.H4.07 G.S6.05 neurotensin_on_gp67.88160NoNoNoNo54
29G.H4.03 G.H4.07 neurotensin_on_gp67.76660NoNoNoNo45
30G.H4.03 G.HG.01 neurotensin_on_gp67.42120NoNoNoNo45
31G.HG.01 G.s6h5.05 neurotensin_on_gp66.66430NoNoNoNo59
32G.s6h5.01 G.s6h5.05 neurotensin_on_gp66.61370YesNoNoNo99
33G.H2.10 G.h2s4.01 neurotensin_on_gp24.97110NoNoYesNo79
34G.S1.05 G.h2s4.01 neurotensin_on_gp79.77220NoNoYesNo99
35G.S6.04 G.s6h5.01 neurotensin_on_gp57.99050NoNoYesNo99
36G.H3.09 G.H4.15 neurotensin_on_gp12.02390YesNoYesNo98
37G.H5.06 I3 neurotensin_on_gp54.47980NoNoYesNo35
38G.H5.06 G.S6.04 neurotensin_on_gp54.59870NoNoNoNo39
39G.H2.07 G.h2s4.01 neurotensin_on_gp47.31240YesNoYesNo99
40G.h2s4.01 b.l7x2 neurotensin_on_gp47.13950YesNoYesNo99
41b.l5x5 b.l7x2 neurotensin_on_gp20.27650YesNoYesNo99
42G.H2.07 b.l9x6 neurotensin_on_gp47.28950YesNoYesNo98
43b.l7x2 b.l9x6 neurotensin_on_gp67.46970YesNoYesNo98
44b.l13x6 b.l9x6 neurotensin_on_gp19.34750YesNoYesNo98
45b.l13x6 b.l15x1 neurotensin_on_gp24.10530YesNoYesNo97
46b.b14x1 b.l9x6 neurotensin_on_gp76.84910YesNoYesNo88
47b.b14x1 b.l15x1 neurotensin_on_gp19.1920YesNoYesNo87
48b.l15x1 b.l17x6 neurotensin_on_gp43.15450YesNoYesNo79
49G.H2.06 b.b14x1 neurotensin_on_gp38.35690YesNoYesNo98
50G.H2.06 b.l17x6 neurotensin_on_gp19.14270YesNoYesNo99
51b.b14x1 b.b18x1 neurotensin_on_gp19.22280YesNoNoNo89
52G.H2.06 b.l19x1 neurotensin_on_gp19.17170YesNoYesNo99
53b.b18x1 b.l19x1 neurotensin_on_gp19.15820NoNoYesNo99
54G.H5.13 I3 neurotensin_on_gp52.53470YesNoYesNo85
556x26 G.H5.13 neurotensin_on_gp52.72850YesNoYesNo48
565x68 G.H5.16 neurotensin_on_gp52.40550NoNoNoNo66
576x26 G.H5.16 neurotensin_on_gp52.52660YesNoNoNo46
586x30 G.H5.20 neurotensin_on_gp51.31280NoNoNoNo79
595x65 6x30 neurotensin_on_gp51.79890NoNoNoNo87
605x65 5x68 neurotensin_on_gp51.92030NoNoNoNo86
61G.H5.20 G.H5.25 neurotensin_on_gp51.19110NoNoYesNo97
622x36 2x38 neurotensin_on_gp47.2720NoNoYesNo77
632x38 3x49 neurotensin_on_gp47.64160.954717YesNoNoYes78
642x42 3x49 neurotensin_on_gp47.88770YesNoNoYes88
653x46 3x50 neurotensin_on_gp48.98350NoNoNoYes99
663x50 G.H5.23 neurotensin_on_gp49.36030NoYesYesNo94
67G.H5.23 G.H5.25 neurotensin_on_gp49.72740YesNoYesNo47
68b.l17x5 b.l17x6 neurotensin_on_gp62.11880NoNoYesNo69
69b.l17x5 b.l19x2 neurotensin_on_gp1000NoNoYesNo69
70b.l17x3 b.l19x2 neurotensin_on_gp74.09550YesNoYesNo99
71b.b19x4 b.l17x3 neurotensin_on_gp49.41010YesNoYesNo89
72b.b19x2 b.b19x4 neurotensin_on_gp24.4050YesNoYesNo68
73b.b17x7 b.b19x2 neurotensin_on_gp21.9760YesNoYesNo86
74b.b17x7 b.b21x1 neurotensin_on_gp39.35520YesNoYesNo87
75b.1x19 b.b21x1 neurotensin_on_gp35.91380NoNoYesNo67
76b.1x15 b.1x19 neurotensin_on_gp26.85550NoNoNoNo76
77b.1x15 g.h1x15 neurotensin_on_gp25.73650NoNoNoNo78
78b.1x11 g.h1x15 neurotensin_on_gp24.61760YesNoNoNo88
79b.1x11 g.h1x11 neurotensin_on_gp19.02270YesNoNoNo89
80b.1x12 g.h1x11 neurotensin_on_gp17.90370NoNoNoNo69
81b.1x12 b.1x8 neurotensin_on_gp12.30880NoNoNoNo65
82b.1x8 g.h1x8 neurotensin_on_gp11.18980NoNoNoNo57
83b.l17x5 b.l19x1 neurotensin_on_gp38.17840NoNoYesNo69
84b.b19x4 b.b20x6 neurotensin_on_gp22.26410YesNoYesNo86
85b.b17x7 b.b20x6 neurotensin_on_gp65.87750YesNoYesNo86
86b.b20x4 b.l17x3 neurotensin_on_gp23.78770YesNoYesNo89
87b.b20x4 b.b20x6 neurotensin_on_gp44.52240YesNoYesNo86
88b.b20x2 b.l19x2 neurotensin_on_gp24.69870YesNoYesNo69
89b.b20x2 b.b20x4 neurotensin_on_gp23.78780YesNoYesNo68
90b.b1x6 b.b28x3 neurotensin_on_gp15.29930YesNoYesNo97
91b.b27x4 b.b28x3 neurotensin_on_gp16.42850NoNoYesNo57
92b.b27x4 b.b27x5 neurotensin_on_gp15.96080NoNoNoNo59
93b.b27x5 b.l25x3 neurotensin_on_gp10.30960NoNoYesNo99
94b.b14x5 b.l10x1 neurotensin_on_gp11.80250YesNoNoNo53
95b.b11x1 b.l10x1 neurotensin_on_gp11.99370NoNoNoNo53
96b.b11x1 b.l10x4 neurotensin_on_gp12.08540NoNoYesNo53
97b.l10x4 b.l12x2 neurotensin_on_gp12.22810YesNoNoNo36
98b.b9x2 b.l12x2 neurotensin_on_gp12.82310YesNoNoNo56
99b.b9x2 b.l12x1 neurotensin_on_gp20.62020YesNoNoNo56
100b.b8x3 b.l12x1 neurotensin_on_gp20.7140NoNoNoNo66
101b.b7x1 b.b8x3 neurotensin_on_gp20.90470YesNoNoNo46
102b.b10x5 b.b7x1 neurotensin_on_gp22.43020YesNoYesNo94
103b.b10x5 b.b11x2 neurotensin_on_gp22.82240YesNoNoNo97
104b.b10x3 b.b11x2 neurotensin_on_gp22.92150YesNoNoNo87
105b.l11x1 b.l9x6 neurotensin_on_gp19.04590NoNoYesNo98
106b.b11x6 b.l11x1 neurotensin_on_gp23.97770YesNoNoNo99
107b.b11x6 b.l9x3 neurotensin_on_gp11.93880YesNoYesNo99
108b.b11x6 b.l9x7 neurotensin_on_gp11.70830YesNoYesNo97
109b.b11x4 b.l9x3 neurotensin_on_gp11.6710YesNoYesNo99
110b.b11x4 b.l9x7 neurotensin_on_gp11.60990YesNoYesNo97
111b.b10x3 b.b11x4 neurotensin_on_gp23.22010YesNoYesNo89
112b.b17x5 b.b17x7 neurotensin_on_gp47.27590YesNoYesNo78
113b.b16x5 b.b17x5 neurotensin_on_gp40.05440YesNoYesNo57
114b.b16x5 b.l20x1 neurotensin_on_gp36.38560YesNoNoNo56
115b.l18x5 b.l20x1 neurotensin_on_gp35.1610NoNoNoNo26
116b.l18x3 b.l18x5 neurotensin_on_gp26.00110YesNoNoNo52
117b.l18x1 b.l18x3 neurotensin_on_gp14.49410YesNoYesNo65
1182x36 2x40 neurotensin_on_gp47.02540NoNoNoNo78
1191x57 2x40 neurotensin_on_gp46.83910.988385NoNoNoNo78
1201x53 1x57 neurotensin_on_gp45.00672.27497NoNoNoNo97
1211x53 7x50 neurotensin_on_gp43.0763.24411NoNoNoYes99
1222x54 7x46 neurotensin_on_gp34.72636.81048NoNoNoNo79
1232x54 7x42 neurotensin_on_gp34.60060NoNoYesYes77
1242x60 2x64 neurotensin_on_gp10.96440YesYesYesNo64
1252x64 Lig neurotensin_on_gp10.29060YesNoYesYes40
1262x60 7x34 neurotensin_on_gp15.23110YesYesYesNo64
1272x42 3x46 Shared48.747645.3551YesNoNoNo89
1281x50 7x50 Shared42.70239.0857YesYesNoYes99
1291x50 2x50 Shared42.078747.2284YesYesYesNo99
1302x50 7x46 Shared35.110447.7383YesNoNoNo99
1312x60 7x42 Shared33.158231.876YesYesYesYes67
1327x34 Lig Shared10.300423.8102YesNoYesYes40
1332x65 2x66 neurotensin_off0.54723511.673NoNoNoYes45
1342x60 2x65 neurotensin_off012.8706YesYesNoNo64
1352x60 3x32 neurotensin_off036.8492YesYesYesNo67
1363x32 7x41 neurotensin_off055.4097YesNoNoYes77
1376x48 7x41 neurotensin_off0.53821724.2527YesYesNoYes87
1387x41 7x42 neurotensin_off0.4102637.2051NoYesYesYes77
1392x53 7x41 neurotensin_off0100NoNoNoYes77
1402x53 7x46 neurotensin_off0.28227849.4216NoNoNoNo79
1417x49 7x50 neurotensin_off037.3422NoYesNoYes99
1427x49 7x53 neurotensin_off015.2851NoYesNoYes99
1437x53 8x50 neurotensin_off011.8197NoYesYesYes98
1442x53 3x35 neurotensin_off0.14115152.9904NoNoNoNo77
1452x49 3x35 neurotensin_off051.6726NoYesNoNo87
1462x49 4x50 neurotensin_off0.22036249.8617NoYesYesYes89
1472x45 4x50 neurotensin_off0.14105249.5924NoNoYesYes99
1482x45 3x42 neurotensin_off0.00037060546.9831NoNoNoNo98
1493x42 4x49 neurotensin_off048.4741NoNoNoYes87
1503x45 4x49 neurotensin_off046.4348NoNoNoYes77
1512x42 3x45 neurotensin_off0.14115145.9803YesNoNoNo87
1523x46 6x37 neurotensin_off044.7082NoNoYesNo98
1533x50 6x37 neurotensin_off031.0968NoYesYesNo98
1543x28 3x32 neurotensin_off4.8834131.1618YesYesYesNo67
1552x60 7x38 neurotensin_off0.1353761.3809YesYesNoNo66
1563x28 3x29 neurotensin_off0.54385122.3769YesYesYesNo64
1573x36 6x48 neurotensin_off0.14095310.6823NoNoYesYes78
1583x36 5x461 neurotensin_off010.1724NoNoNoYes76
1596x54 7x38 neurotensin_off035.6444YesYesNoNo56
1606x40 7x49 neurotensin_off027.1217NoNoNoYes89
1613x43 6x40 neurotensin_off0.14112626.4916NoNoNoNo88
1623x43 6x41 neurotensin_off025.8615NoNoNoNo88
1635x54 6x41 neurotensin_off025.2315NoNoNoNo88
1643x47 5x54 neurotensin_off023.3485NoNoNoNo98
1655x58 6x37 neurotensin_off1.8496420.7657YesYesYesNo98
1665x58 5x61 neurotensin_off032.1862YesYesNoNo99
1673x51 5x61 neurotensin_off021.2491NoYesNoNo89
1683x47 5x58 neurotensin_off1.5499222.7569NoNoYesYes99
1693x54 3x55 neurotensin_off012.7047NoNoNoYes97
1705x40 6x55 neurotensin_off4.8899610.4538NoNoYesYes66
1715x40 6x59 neurotensin_off4.3468318.0819NoNoNoYes63
1726x54 Lig neurotensin_off025.3277YesYesYesYes50
1735x40 Lig neurotensin_off013.758NoNoYesYes60
1747x34 7x38 neurotensin_off0.0028660124.8299YesNoNoNo46
1756x44 6x48 neurotensin_off4.9213911.4085YesNoYesYes98
1763x55 5x64 neurotensin_off017.4711NoYesNoNo75
1773x50 3x53 neurotensin_off018.3681NoYesNoNo98
1783x53 6x30 neurotensin_off017.3821NoNoNoNo87
1795x72 6x30 neurotensin_off016.5043NoNoNoNo57
1807x27 Lig neurotensin_off0.27306211.5023NoNoYesYes20
1817x30 Lig neurotensin_off0.280413.8206YesYesYesYes40
1823x29 4x61 neurotensin_off013.9312YesNoNoNo45

Here, those paths that begin and end at given residue pair(s) or that pass through a residue are used to generate a novel metapath. Such a path filtering is particularly recommended if some information on allosteric residues is available. The selection syntax for a residue pair ("Pairs") is C:C:c534,A:A:?600 (the lower-case "c" stands for cytosine and "?" indicates any non standard amino acid or nucleotide residue). Selection of more than one apical residue pair has the following syntax: C:C:c534,A:A:?600,C:C:c534,A:A:E41. Only one residue can be selected as a tail ("Tail"). For midway residue(s), each residue must be separated by a comma as well e.g. A:A:?600,A:A:E41.

Midway



Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.


2D representation of the interactions of this orthosteric/allosteric ligand.


Node1Node2OwnerNet1LinkStrengthNet2LinkStrengthComm1Comm2Node1ShellNode2Shell
1x32E1neurotensin_off5.2400221
2x603x32neurotensin_off4.6501222
2x607x38Shared3.947.231222
2x643x28neurotensin_off7.2200212
E1E1x49Shared7.6311.444212
E1E2neurotensin_off7.3304211
3x25E1x50neurotensin_off3.9203222
3x21E2neurotensin_off3.2700021
3x223x26neurotensin_off10.7204222
3x22E2Shared8.183.9854221
3x283x29Shared12.916.4550221
3x283x32Shared13.385.1450222
3x294x61neurotensin_off3.5900212
3x294x65Shared10.7813.170211
4x614x64neurotensin_off7.5300022
4x644x65neurotensin_off4.5204021
4x64E2neurotensin_off3.0404021
4x65E2x52Shared8.399.2250212
E2E2Shared36.9475.054211
E2E2x51Shared11.315.944211
E2x51E2x52Shared6.994.3754212
5x35E2Shared7.615.034021
5x36E2neurotensin_off3.0700021
5x406x55Shared7.526.890011
5x406x59Shared3.275.7250012
5x40Ligneurotensin_off4.6500010
5x436x55Shared6.036.631021
6x516x54Shared3.097.7151221
6x516x55Shared10.299.7751221
6x546x55Shared4.264.2651211
6x547x34Shared12.3511.8351211
6x547x37Shared11.648.411212
6x547x38neurotensin_off6.0301212
6x54Ligneurotensin_off12.6701210
6x576x61neurotensin_off4.3700012
6x577x33neurotensin_off7.4600012
6x57Ligneurotensin_off8.2900010
6x58LigShared30.1721.170210
7x27E3neurotensin_off5.7901211
7x30E3Shared13.54.8251211
E3LigShared6.6835.61210
7x267x30neurotensin_off4.6900221
7x27LigShared3.0615.41210
7x287x32neurotensin_off3.4500022
7x297x30neurotensin_off6.1900021
7x30LigShared8.4113.9251210
7x317x32neurotensin_off3.2700212
7x317x35neurotensin_off6.5700212
7x337x37Shared5.197.1350222
7x347x38Shared5.8112.7951212
7x34LigShared12.996.6451210
7x277x28neurotensin_off2.301212
1x311x32neurotensin_off1.5300222
6x536x57neurotensin_off1.5200021
LigNTneurotensin_on_gp011.391201
7x31Ligneurotensin_on_gp05.9050210
E1Ligneurotensin_on_gp06.3454210
E2Ligneurotensin_on_gp013.884210
E2x51Ligneurotensin_on_gp03.1254210
2x64Ligneurotensin_on_gp04.3950210
3x29Ligneurotensin_on_gp05.860210
4x65Ligneurotensin_on_gp04.9450210
6x55Ligneurotensin_on_gp07.8951210
E2NTneurotensin_on_gp019.0754211
E1NTneurotensin_on_gp025.2854211
NTNTneurotensin_on_gp04.4050211
7x27NTneurotensin_on_gp03.811211
7x31NTneurotensin_on_gp019.3750211
1x32NTneurotensin_on_gp05.2550221
7x32NTneurotensin_on_gp014.6350221
1x317x32neurotensin_on_gp03.820222
2x602x64neurotensin_on_gp06.4151221
2x603x28neurotensin_on_gp03.931222
2x607x34neurotensin_on_gp04.491221
2x643x29neurotensin_on_gp03.610211
2x647x34neurotensin_on_gp07.740211
3x21E1x50neurotensin_on_gp03.5150022
3x25E2neurotensin_on_gp03.5453221
3x26E2neurotensin_on_gp030221
3x326x51neurotensin_on_gp06.1750222
5x36E2x52neurotensin_on_gp05.1150022
6x547x30neurotensin_on_gp09.261211
6x547x33neurotensin_on_gp05.341212
6x587x30neurotensin_on_gp07.220211
6x61E3neurotensin_on_gp018.220021
E3E3neurotensin_on_gp011.021211
7x26E3neurotensin_on_gp03.420221
7x277x31neurotensin_on_gp015.541211
7x307x31neurotensin_on_gp04.3551211
1x30NTneurotensin_on_gp03.450021
1x31NTneurotensin_on_gp03.680221
E1x50E2neurotensin_on_gp015.3753221
3x293x32neurotensin_on_gp04.1150212
3x326x55neurotensin_on_gp05.8650221
7x28NTneurotensin_on_gp02.190021
6x566x57neurotensin_on_gp02.120021
6x537x33neurotensin_on_gp01.9650022
7x297x33neurotensin_on_gp01.070022
5x34E2neurotensin_on_gp00.770221

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Difference Members
Id Description
neurotensin_on_gp nts1_on_gp
neurotensin_off nts1_off
Network Difference
Value neurotensin_on_gp neurotensin_off
Imin 2.99 2.96
Number of Linked Nodes 1001 256
Number of Specific Nodes 749 (74.83%) 4  (1.56%)
Number of Shared Nodes 252 (25.17%) 252  (98.44%)
Number of Links 1177 296
Number of Specific Links 1024 (87.00%) 143  (48.31%)
Number of Shared Links 153 (13.00%) 153  (51.69%)
Number of Hubs 181 44
Number of Specific Hubs 160 (88.40%) 23  (52.27%)
Number of Shared Hubs 21 (11.60%) 21  (47.73%)
Average % Shared Neighbours (Jaccard) 10.07
Average % Shared Neighbours (Otsuka) 12.73
Average % Shared Neighbours (Overlap Coefficient) 15.54
Average % Shared Cliques (k3-6) 51.09
Graphlets Similarity 0.664423
Paths Difference
Value neurotensin_on_gp neurotensin_off
Number Of Nodes in MetaPath 124 55
Specific Nodes in MetaPath 112 (90.32%) 43  (78.18%)
Shared Nodes in MetaPath 252 (25.17%) 252  (25.17%)
Number Of Links MetaPath 132 56
Specific Links in MetaPath 126 (95.45%) 50  (89.29%)
Shared Links in MetaPath 153 (13.00%) 153  (13.00%)
Number of Shortest Paths 5625556 66264
Length Of Smallest Path 3 3
Average Path Length 43.7092 15.8683
Length of Longest Path 85 32
Minimum Path Strength 0.63 1.295
Average Path Strength 6.02454 6.05968
Maximum Path Strength 28.385 21.58
Minimum Path Correlation 0.7 0.7
Average Path Correlation 0.987041 0.9332
Maximum Path Correlation 1 0.99
Minimum % Of Corr. Nodes 1.31579 3.84615
Average % Of Corr. Nodes 29.7969 47.5072
Maximum % Of Corr. Nodes 100 100
Minimum Path Hubs % 0 0
Average Path Hubs % 53.2755 39.9957
Maximum Path Hubs % 100 100

Details about the values in these tables can be found in the corresponding documentation page .

You can download a compressed (zip) file with structure(s), 3D outputs (as PyMol and VMD scripts) and numerical data files (as csv and plain text files).

Download neurotensin_off_on_gp.zip<



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