psnGPCR

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Orange: nodes, hubs and links specific of nts1_on_allo network

Green: nodes, hubs and links shared by both networks

Purple: nodes, hubs and links specific of nts1_on network

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Owner: the name of the network the link belong to or "Shared" if the corresponding link is present in both networks.

Strength: the interaction strength between the two nodes or 0 if the link is not present.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Owner	nts1_on_allo Int. Strength	nts1_on Int. Strength	nts1_on_allo Hub1?	nts1_on Hub1?	nts1_on_allo Hub2?	nts1_on Hub2?	ConSurf1	ConSurf2
1	7x24	Lig	nts1_on_allo	7.21	0	No	No	Yes	Yes	4	0
2	E1.H132	Lig	nts1_on_allo	4.36	0	Yes	No	Yes	Yes	0	0
3	3x29	Lig	nts1_on_allo	9.42	0	Yes	No	Yes	Yes	4	0
4	E2.R212	NT.L54	nts1_on_allo	4.86	0	No	No	No	No	0	0
5	NT.T58	NT.V56	nts1_on_allo	6.35	0	No	No	No	No	0	0
6	1x36	2x61	nts1_on_allo	4.42	0	No	No	No	No	6	6
7	1x39	2x65	nts1_on_allo	7.25	0	Yes	Yes	Yes	No	7	4
8	1x39	7x38	nts1_on_allo	4.65	0	Yes	Yes	Yes	Yes	7	6
9	1x39	7x42	nts1_on_allo	9.93	0	Yes	Yes	Yes	No	7	7
10	1x45	1x46	nts1_on_allo	3.68	0	No	No	No	No	6	8
11	1x45	7x47	nts1_on_allo	4.76	0	No	No	No	No	6	7
12	1x50	2x47	nts1_on_allo	4.69	0	No	No	No	No	9	9
13	2x39	3x49	nts1_on_allo	4.28	0	No	No	Yes	No	8	8
14	2x39	3x50	nts1_on_allo	6.54	0	No	No	Yes	No	8	9
15	2x40	2x41	nts1_on_allo	18.51	0	No	Yes	No	No	8	5
16	2x41	4x42	nts1_on_allo	6.24	0	No	No	No	No	5	7
17	2x42	I2x57	nts1_on_allo	5.25	0	No	Yes	Yes	No	8	7
18	2x43	7x53	nts1_on_allo	11.72	0	No	No	No	Yes	8	9
19	2x46	2x49	nts1_on_allo	4.5	0	Yes	No	No	No	9	8
20	2x46	3x43	nts1_on_allo	4.47	0	Yes	No	Yes	No	9	8
21	2x46	7x49	nts1_on_allo	6.87	0	Yes	No	No	No	9	9
22	2x50	7x46	nts1_on_allo	8.83	0	Yes	Yes	No	No	9	9
23	2x53	7x41	nts1_on_allo	3.89	0	No	No	No	No	7	7
24	2x54	2x57	nts1_on_allo	5.65	0	No	No	Yes	Yes	7	8
25	2x54	7x46	nts1_on_allo	7.51	0	No	No	No	No	7	9
26	2x56	3x32	nts1_on_allo	4.15	0	No	No	Yes	No	7	7
27	2x56	7x42	nts1_on_allo	4	0	No	No	Yes	No	7	7
28	2x60	2x65	nts1_on_allo	8.2	0	Yes	Yes	Yes	No	6	4
29	2x61	2x65	nts1_on_allo	5.71	0	No	No	Yes	No	6	4
30	2x62	2x66	nts1_on_allo	15.43	0	No	No	Yes	Yes	5	5
31	2x62	E1.H131	nts1_on_allo	8.71	0	No	No	No	No	5	0
32	2x63	E1x51	nts1_on_allo	4.69	0	No	No	No	No	5	3
33	2x65	7x35	nts1_on_allo	10.2	0	Yes	No	No	No	4	3
34	2x66	2x67	nts1_on_allo	12.26	0	Yes	Yes	No	No	5	5
35	2x66	E1.H131	nts1_on_allo	13.75	0	Yes	Yes	No	No	5	0
36	2x67	E1.H131	nts1_on_allo	4.15	0	No	No	No	No	5	0
37	E1.H132	E1x49	nts1_on_allo	16.78	0	Yes	No	No	No	0	5
38	3x28	E1x50	nts1_on_allo	8.68	0	Yes	Yes	Yes	Yes	6	8
39	3x28	3x32	nts1_on_allo	12.35	0	Yes	Yes	Yes	No	6	7
40	3x37	5x461	nts1_on_allo	8.9	0	No	No	No	No	7	6
41	3x41	4x49	nts1_on_allo	8.56	0	No	No	No	No	6	7
42	3x43	6x44	nts1_on_allo	3.93	0	Yes	No	Yes	No	8	9
43	3x43	Allo3	nts1_on_allo	3.86	0	Yes	No	Yes	No	8	0
44	3x46	Allo3	nts1_on_allo	12.56	0	No	No	Yes	No	9	0
45	3x49	I2x57	nts1_on_allo	16.24	0	Yes	No	Yes	No	8	7
46	3x50	3x54	nts1_on_allo	5.01	0	Yes	No	Yes	No	9	9
47	3x50	Allo3	nts1_on_allo	39.37	0	Yes	No	Yes	No	9	0
48	3x52	3x56	nts1_on_allo	3.86	0	No	No	Yes	No	4	6
49	3x54	Allo3	nts1_on_allo	4.63	0	Yes	No	Yes	No	9	0
50	3x55	3x56	nts1_on_allo	4.42	0	Yes	No	Yes	No	7	6
51	I2x51	I2x54	nts1_on_allo	7.44	0	No	No	No	No	7	4
52	4x42	I2x57	nts1_on_allo	7.53	0	No	No	Yes	No	7	7
53	4x43	4x46	nts1_on_allo	4.36	0	No	No	No	No	3	7
54	4x44	4x47	nts1_on_allo	4.59	0	No	No	No	No	4	4
55	4x51	4x55	nts1_on_allo	4.15	0	No	No	No	No	3	4
56	E2.Q210	E2x51	nts1_on_allo	7.09	0	No	No	No	No	0	4
57	E2.G216	E2.N211	nts1_on_allo	5.09	0	No	No	No	Yes	0	0
58	E2.G221	E2.S213	nts1_on_allo	3.71	0	No	No	No	No	0	0
59	E2.A219	E2.H218	nts1_on_allo	5.85	0	No	No	No	No	0	0
60	E2.I228	E2.T227	nts1_on_allo	4.56	0	No	No	No	No	0	0
61	5x47	5x48	nts1_on_allo	3.77	0	Yes	No	No	No	8	5
62	5x47	6x44	nts1_on_allo	4.29	0	Yes	No	Yes	No	8	9
63	5x54	5x58	nts1_on_allo	4.25	0	No	No	Yes	No	8	9
64	5x54	6x44	nts1_on_allo	3.77	0	No	No	Yes	No	8	9
65	5x72	6x26	nts1_on_allo	5.53	0	No	No	No	No	5	4
66	5x74	6x26	nts1_on_allo	13.96	0	No	No	No	No	4	4
67	5x75	5x76	nts1_on_allo	4.06	0	No	No	No	No	3	3
68	6x27	6x31	nts1_on_allo	7.85	0	No	No	No	No	3	5
69	6x28	6x31	nts1_on_allo	11.68	0	No	No	No	No	5	5
70	6x28	6x32	nts1_on_allo	13.6	0	No	No	No	No	5	8
71	6x32	6x35	nts1_on_allo	4.51	0	No	No	No	No	8	7
72	6x35	6x36	nts1_on_allo	3.92	0	No	No	No	No	7	8
73	6x35	7x55	nts1_on_allo	3.64	0	No	No	No	No	7	6
74	6x36	7x56	nts1_on_allo	4.81	0	No	No	No	No	8	7
75	6x40	Allo3	nts1_on_allo	10.62	0	No	No	Yes	No	8	0
76	6x54	7x38	nts1_on_allo	3.62	0	Yes	Yes	Yes	Yes	5	6
77	E3.E332	E3.S330	nts1_on_allo	8.62	0	No	No	No	No	0	0
78	7x30	7x31	nts1_on_allo	5.44	0	Yes	Yes	No	No	4	4
79	7x38	7x42	nts1_on_allo	5.81	0	Yes	Yes	Yes	No	6	7
80	7x53	8x50	nts1_on_allo	4.13	0	No	Yes	Yes	Yes	9	8
81	7x53	Allo3	nts1_on_allo	6.84	0	No	Yes	Yes	No	9	0
82	7x54	8x54	nts1_on_allo	18.12	0	No	No	Yes	No	7	7
83	7x56	Allo3	nts1_on_allo	6.76	0	No	No	Yes	No	7	0
84	8x47	Allo3	nts1_on_allo	4.87	0	No	No	Yes	No	8	0
85	8x50	Allo3	nts1_on_allo	7.1	0	Yes	Yes	Yes	No	8	0
86	3x29	4x61	nts1_on_allo	3.59	0	Yes	No	No	No	4	5
87	4x60	5x39	nts1_on_allo	3.53	0	No	No	No	No	7	6
88	E2.G208	E2.Q210	nts1_on_allo	3.29	0	No	No	No	No	0	0
89	E2.G216	E2.Q217	nts1_on_allo	3.29	0	No	No	No	No	0	0
90	3x54	3x55	nts1_on_allo	3.27	0	Yes	No	Yes	No	9	7
91	NT.S51	NT.S52	nts1_on_allo	3.26	0	No	No	No	No	0	0
92	5x52	5x55	nts1_on_allo	3.23	0	No	No	No	No	3	5
93	1x52	8x57	nts1_on_allo	3.17	0	No	No	No	No	6	5
94	1x54	2x48	nts1_on_allo	3.15	0	No	No	No	No	8	6
95	5x74	5x75	nts1_on_allo	3.14	0	No	No	No	No	4	3
96	1x49	8x54	nts1_on_allo	3.01	0	No	No	Yes	No	9	7
97	1x32	1x36	nts1_on_allo	3	0	No	No	No	No	5	6
98	4x59	4x62	nts1_on_allo	2.98	0	No	No	No	No	5	5
99	5x53	5x57	nts1_on_allo	2.98	0	No	No	No	No	6	7
100	E2.D215	NT.S51	nts1_on_allo	2.94	0	No	No	No	No	0	0
101	8x48	8x52	nts1_on_allo	2.93	0	No	No	No	No	4	4
102	5x63	5x66	nts1_on_allo	2.92	0	No	No	No	No	4	5
103	E2.S213	NT.E53	nts1_on_allo	2.87	0	No	No	No	No	0	0
104	3x54	5x65	nts1_on_allo	2.85	0	Yes	No	No	No	9	8
105	7x48	7x52	nts1_on_allo	2.85	0	No	No	No	No	6	8
106	4x56	5x46	nts1_on_allo	2.83	0	No	No	No	No	6	5
107	5x41	5x44	nts1_on_allo	2.83	0	No	No	No	No	5	6
108	3x21	E1x50	nts1_on_allo	2.81	0	No	No	Yes	Yes	8	8
109	2x52	2x551	nts1_on_allo	2.77	0	No	No	No	No	8	5
110	3x52	I2x56	nts1_on_allo	2.77	0	No	No	No	No	4	4
111	NT.E53	NT.L54	nts1_on_allo	2.65	0	No	No	No	No	0	0
112	5x67	5x70	nts1_on_allo	2.62	0	No	No	No	No	4	4
113	1x55	8x57	nts1_on_allo	2.59	0	No	No	No	No	4	5
114	4x39	I2x55	nts1_on_allo	2.59	0	No	No	No	No	3	4
115	6x57	7x33	nts1_on_allo	2.49	0	No	No	No	No	4	4
116	4x41	4x44	nts1_on_allo	2.48	0	No	No	No	No	5	4
117	7x25	7x26	nts1_on_allo	2.44	0	No	No	No	No	2	1
118	8x54	8x55	nts1_on_allo	2.44	0	Yes	No	No	No	7	4
119	8x51	8x55	nts1_on_allo	2.43	0	No	No	No	No	9	4
120	6x56	6x60	nts1_on_allo	2.34	0	No	No	No	No	6	5
121	1x28	1x30	nts1_on_allo	2.3	0	No	No	No	No	3	2
122	2x44	2x47	nts1_on_allo	1.95	0	No	No	No	No	6	9
123	1x48	1x49	nts1_on_allo	1.84	0	No	No	No	No	5	9
124	4x53	4x54	nts1_on_allo	1.71	0	No	No	No	No	8	4
125	E2.G221	E2.L222	nts1_on_allo	1.71	0	No	No	No	No	0	0
126	3x41	5x50	nts1_on_allo	1.64	0	No	No	Yes	Yes	6	9
127	5x76	6x28	nts1_on_allo	1.64	0	No	No	No	No	3	5
128	I2x53	I2x57	nts1_on_allo	1.61	0	No	No	Yes	No	6	7
129	4x44	4x48	nts1_on_allo	1.61	0	No	No	No	No	4	4
130	5x56	5x59	nts1_on_allo	1.59	0	No	No	No	No	5	3
131	5x62	6x37	nts1_on_allo	1.58	0	No	No	No	No	6	8
132	1x29	2x67	nts1_on_allo	1.54	0	No	No	No	No	2	5
133	4x43	4x47	nts1_on_allo	1.53	0	No	No	No	No	3	4
134	5x42	5x46	nts1_on_allo	1.52	0	No	No	No	No	5	5
135	5x67	5x68	nts1_on_allo	1.52	0	No	No	No	No	4	6
136	I2x52	I2x55	nts1_on_allo	1.5	0	No	No	No	No	4	4
137	1x34	1x38	nts1_on_allo	1.49	0	No	No	No	No	5	4
138	6x46	7x40	nts1_on_allo	1.49	0	No	No	No	No	6	7
139	7x36	7x40	nts1_on_allo	1.49	0	No	No	No	No	6	7
140	5x68	6x30	nts1_on_allo	1.41	0	No	No	No	No	6	7
141	2x48	2x52	nts1_on_allo	1.38	0	No	No	No	No	6	8
142	3x50	3x53	nts1_on_allo	1.38	0	Yes	No	No	No	9	8
143	5x32	5x33	nts1_on_allo	1.37	0	No	No	No	No	4	4
144	4x39	4x40	nts1_on_allo	1.32	0	No	No	No	No	3	4
145	1x31	7x32	nts1_on_allo	1.27	0	No	No	No	No	3	1
146	7x27	Lig	Shared	21.48	29.24	No	Yes	Yes	Yes	2	0
147	Lig	Lig	Shared	15.63	8.19	Yes	Yes	Yes	Yes	0	0
148	5x33	Lig	Shared	5.17	1.5	No	No	Yes	Yes	4	0
149	6x58	Lig	Shared	12.94	17.32	No	No	Yes	Yes	4	0
150	E3.W334	Lig	Shared	31.27	20.47	No	Yes	Yes	Yes	0	0
151	7x30	Lig	Shared	10.91	10.91	Yes	Yes	Yes	Yes	4	0
152	E2.V223	Lig	Shared	6.31	15.14	No	No	Yes	Yes	0	0
153	2x64	Lig	Shared	8.79	10.05	No	Yes	Yes	Yes	4	0
154	7x34	Lig	Shared	9.53	6.04	Yes	Yes	Yes	Yes	4	0
155	6x55	Lig	Shared	6.07	8.5	No	Yes	Yes	Yes	6	0
156	E2.H218	NT.S51	Shared	15.34	8.37	No	No	No	No	0	0
157	E1.H132	NT.L54	Shared	3.86	7.71	Yes	No	No	No	0	0
158	7x31	NT.V56	Shared	12.45	16.61	No	No	No	No	4	0
159	7x28	NT.N57	Shared	13.46	8.08	No	No	No	No	1	0
160	7x32	NT.T58	Shared	13.73	4.99	No	No	No	No	1	0
161	1x28	1x31	Shared	5.89	5.89	No	No	No	No	3	3
162	1x32	2x66	Shared	29.01	12.76	No	No	Yes	Yes	5	5
163	1x35	1x39	Shared	6.31	8.83	No	No	Yes	Yes	5	7
164	1x35	7x35	Shared	4.56	10.65	No	No	No	No	5	3
165	1x39	2x57	Shared	10.78	3.59	Yes	Yes	Yes	Yes	7	8
166	1x39	2x61	Shared	4.69	3.52	Yes	Yes	No	No	7	6
167	1x42	7x47	Shared	4.42	7.37	No	No	No	No	7	7
168	1x43	1x47	Shared	15.56	5.19	No	Yes	No	No	7	6
169	1x43	2x54	Shared	6.09	4.87	No	Yes	No	No	7	7
170	1x43	2x57	Shared	7.46	6.22	No	Yes	Yes	Yes	7	8
171	1x47	2x51	Shared	4.42	2.95	No	No	No	No	6	7
172	1x47	2x55	Shared	4.42	2.95	No	No	No	No	6	5
173	1x50	2x50	Shared	12.12	4.04	No	No	Yes	Yes	9	9
174	1x50	7x50	Shared	9.77	6.52	No	No	No	No	9	9
175	1x51	2x51	Shared	5.9	2.95	No	No	No	No	4	7
176	1x52	8x54	Shared	7.87	6.55	No	No	Yes	No	6	7
177	1x53	8x50	Shared	5.19	5.19	No	No	Yes	Yes	9	8
178	1x56	8x50	Shared	3.89	7.78	No	No	Yes	Yes	7	8
179	1x56	8x53	Shared	7.6	3.04	No	No	No	No	7	6
180	2x38	3x49	Shared	11.29	4.23	No	Yes	Yes	No	7	8
181	2x38	I2x57	Shared	10.54	1.51	No	Yes	Yes	No	7	7
182	2x42	3x45	Shared	5.58	5.58	No	Yes	No	No	8	7
183	2x42	3x49	Shared	16	8.62	No	Yes	Yes	No	8	8
184	2x43	3x46	Shared	6.92	4.15	No	No	No	No	8	9
185	2x45	3x42	Shared	10.43	8.94	No	No	No	Yes	9	8
186	2x45	4x46	Shared	7.74	4.64	No	No	No	No	9	7
187	2x45	4x50	Shared	4.94	6.18	No	No	No	Yes	9	9
188	2x46	2x50	Shared	5.43	5.43	Yes	No	Yes	Yes	9	9
189	2x46	3x42	Shared	5.49	5.49	Yes	No	No	Yes	9	8
190	2x49	3x39	Shared	7.99	4.8	No	No	No	No	8	9
191	2x49	3x42	Shared	5.96	4.47	No	No	No	Yes	8	8
192	2x50	7x49	Shared	6.73	9.42	Yes	Yes	No	No	9	9
193	2x51	2x55	Shared	6.92	6.92	No	No	No	No	7	5
194	2x53	3x35	Shared	5.07	3.38	No	No	No	No	7	7
195	2x551	3x31	Shared	5.54	6.92	No	No	No	No	5	5
196	2x59	E1x52	Shared	3.93	3.93	No	No	No	Yes	6	7
197	2x59	3x28	Shared	6.31	11.36	No	No	Yes	Yes	6	6
198	2x60	3x28	Shared	6.73	4.49	Yes	Yes	Yes	Yes	6	6
199	2x60	3x32	Shared	8.14	9.3	Yes	Yes	Yes	No	6	7
200	2x60	7x34	Shared	8.98	5.61	Yes	Yes	Yes	Yes	6	4
201	2x60	7x38	Shared	10.52	9.2	Yes	Yes	Yes	Yes	6	6
202	2x60	7x42	Shared	5.61	11.22	Yes	Yes	Yes	No	6	7
203	2x62	2x63	Shared	11.63	5.81	No	No	No	No	5	5
204	2x64	E1x50	Shared	21.05	4.01	No	Yes	Yes	Yes	4	8
205	2x64	3x28	Shared	15.47	4.13	No	Yes	Yes	Yes	4	6
206	E1x49	E2.G220	Shared	4.06	6.09	No	No	No	No	5	0
207	E1x50	E1x52	Shared	4.01	10.02	Yes	Yes	No	Yes	8	7
208	3x25	E1x50	Shared	6.53	9.14	No	No	Yes	Yes	9	8
209	E1x50	E2x50	Shared	5.22	19.59	Yes	Yes	No	No	8	9
210	3x24	E1x52	Shared	9.03	1.51	No	No	No	Yes	6	7
211	3x22	E2.E209	Shared	16.89	5.2	No	No	No	No	3	0
212	3x25	E2x50	Shared	7.28	7.28	No	No	No	No	9	9
213	3x26	E2.G208	Shared	7.51	6	No	No	No	No	7	0
214	3x28	3x29	Shared	9.93	5.96	Yes	Yes	Yes	No	6	4
215	3x29	4x65	Shared	14.37	10.78	Yes	No	No	Yes	4	6
216	3x30	4x62	Shared	13.4	10.96	No	Yes	No	No	6	5
217	3x32	6x51	Shared	4.12	9.26	Yes	No	No	Yes	7	6
218	3x33	4x61	Shared	19.41	9.7	No	No	No	No	5	5
219	3x36	6x48	Shared	3.64	3.64	No	No	Yes	Yes	7	8
220	3x37	4x56	Shared	14.07	14.07	No	No	No	No	7	6
221	3x37	5x43	Shared	11.63	9.3	No	No	No	No	7	6
222	3x38	4x50	Shared	7.78	7.78	No	No	No	Yes	7	9
223	3x39	6x48	Shared	4.85	4.85	No	No	Yes	Yes	9	8
224	3x40	5x50	Shared	3.74	3.74	No	No	Yes	Yes	8	9
225	3x43	5x54	Shared	4.61	3.07	Yes	No	No	No	8	8
226	3x47	5x57	Shared	4.5	6.01	No	No	No	No	9	7
227	3x47	5x58	Shared	4.47	5.96	No	No	Yes	No	9	9
228	3x51	3x55	Shared	9.41	6.72	Yes	Yes	Yes	No	8	7
229	3x51	3x56	Shared	9.8	6.53	Yes	Yes	Yes	No	8	6
230	3x51	5x60	Shared	6.04	3.63	Yes	Yes	No	No	8	5
231	3x51	5x61	Shared	3.63	3.63	Yes	Yes	No	No	8	9
232	3x55	5x64	Shared	6.47	3.23	Yes	No	No	No	7	5
233	3x56	I2x52	Shared	13.1	1.31	Yes	No	No	No	6	4
234	4x38	4x41	Shared	15.81	9.22	No	No	No	No	8	5
235	4x63	4x64	Shared	5.19	3.89	No	No	No	Yes	4	5
236	4x64	E2.I228	Shared	6.08	6.08	No	Yes	No	No	5	0
237	4x65	E2x52	Shared	10.06	10.06	No	Yes	No	Yes	6	5
238	E2.E209	E2.L222	Shared	14.58	10.6	No	No	No	No	0	0
239	E2.Q210	E2.T227	Shared	8.5	5.67	No	No	No	No	0	0
240	E2.L222	E2.N211	Shared	9.61	8.24	No	No	No	Yes	0	0
241	E2.R212	E2x51	Shared	3.88	11.64	No	No	No	No	0	4
242	5x36	E2x52	Shared	8.84	5.3	No	No	No	Yes	5	5
243	6x58	E2x52	Shared	4.33	5.78	No	No	No	Yes	4	5
244	5x35	E2.I228	Shared	12.16	3.04	No	No	No	No	4	0
245	5x37	6x60	Shared	13.14	4.78	No	No	No	No	4	5
246	5x40	6x59	Shared	6.55	8.18	No	No	No	No	6	3
247	5x41	6x60	Shared	4.51	1.13	No	No	No	No	5	5
248	5x43	6x55	Shared	3.62	14.46	No	No	No	Yes	6	6
249	5x44	6x52	Shared	5.48	12.32	No	No	No	Yes	6	7
250	5x45	5x48	Shared	8.79	8.79	No	No	No	No	5	5
251	5x47	5x51	Shared	4.98	7.46	Yes	No	No	No	8	6
252	5x47	6x49	Shared	3.65	7.31	Yes	No	No	No	8	7
253	5x47	6x52	Shared	11.31	4.53	Yes	No	No	Yes	8	7
254	5x49	5x50	Shared	10.11	4.33	No	No	Yes	Yes	6	9
255	5x49	5x53	Shared	3.93	3.93	No	No	No	No	6	6
256	5x51	6x44	Shared	7.46	4.98	No	No	Yes	No	6	9
257	5x51	6x45	Shared	4.56	3.04	No	No	No	No	6	7
258	5x58	6x37	Shared	6.87	9.61	Yes	No	No	No	9	8
259	5x58	6x41	Shared	4.43	4.43	Yes	No	No	No	9	8
260	5x69	6x30	Shared	4.47	2.98	No	No	No	No	6	7
261	6x44	6x48	Shared	19.04	7.02	Yes	No	Yes	Yes	9	8
262	6x47	7x45	Shared	5.16	3.44	No	No	No	No	9	9
263	6x48	7x41	Shared	9.02	12.03	Yes	Yes	No	No	8	7
264	6x48	7x45	Shared	6.18	8.65	Yes	Yes	No	No	8	9
265	6x51	6x54	Shared	9.26	8.23	No	Yes	Yes	Yes	6	5
266	6x51	6x55	Shared	13.38	8.23	No	Yes	No	Yes	6	6
267	6x54	7x30	Shared	7.2	11.32	Yes	Yes	Yes	Yes	5	4
268	6x54	7x33	Shared	7.48	4.28	Yes	Yes	No	No	5	4
269	6x54	7x34	Shared	15.43	11.32	Yes	Yes	Yes	Yes	5	4
270	6x54	7x37	Shared	12.94	7.76	Yes	Yes	No	Yes	5	6
271	6x58	7x30	Shared	8.25	6.19	No	No	Yes	Yes	4	4
272	E3.D331	E3.S330	Shared	5.89	4.42	No	No	No	No	0	0
273	E3.D331	E3.E332	Shared	10.39	1.3	No	No	No	No	0	0
274	7x30	E3.W334	Shared	5.79	4.82	Yes	Yes	No	Yes	4	0
275	7x23	7x24	Shared	5.25	3.5	No	No	No	No	4	4
276	7x23	7x26	Shared	4.42	8.84	No	No	No	No	4	1
277	7x27	7x28	Shared	5.75	2.3	No	Yes	No	No	2	1
278	7x27	7x31	Shared	18.51	18.51	No	Yes	No	No	2	4
279	7x33	7x37	Shared	7.78	7.78	No	No	No	Yes	4	6
280	7x34	7x38	Shared	18.61	10.47	Yes	Yes	Yes	Yes	4	6
281	7x41	7x42	Shared	8.25	5.16	No	No	Yes	No	7	7
282	7x54	8x50	Shared	4.83	13.29	No	No	Yes	Yes	7	8
283	8x50	8x54	Shared	5.36	8.57	Yes	Yes	Yes	No	8	7
284	4x59	4x60	Shared	3.53	3.53	No	No	No	No	5	7
285	6x50	7x37	Shared	3.5	3.5	No	No	No	Yes	9	6
286	2x52	4x50	Shared	3.42	2.28	No	No	No	Yes	8	9
287	3x38	4x53	Shared	3.42	3.42	No	No	No	No	7	8
288	6x47	7x43	Shared	3.42	3.42	No	No	No	No	9	5
289	2x57	2x58	Shared	3.35	3.35	Yes	Yes	No	No	8	9
290	6x50	7x40	Shared	3.28	4.93	No	No	No	No	9	7
291	7x43	7x48	Shared	3.07	1.54	No	No	No	No	5	6
292	1x38	1x42	Shared	2.98	2.98	No	No	No	No	4	7
293	1x42	7x43	Shared	2.98	2.98	No	No	No	No	7	5
294	3x48	5x57	Shared	2.98	2.98	No	No	No	No	7	7
295	5x65	6x34	Shared	2.98	4.47	No	No	No	Yes	8	7
296	6x49	6x53	Shared	2.98	2.98	No	No	No	No	7	5
297	1x36	1x40	Shared	2.95	1.47	No	No	No	No	6	5
298	E2.D215	E2.S213	Shared	2.94	1.47	No	No	No	No	0	0
299	4x60	4x63	Shared	2.89	2.89	No	No	No	No	7	4
300	5x64	5x68	Shared	2.88	4.32	No	No	No	No	5	6
301	5x40	Lig	Shared	2.85	5.71	No	No	Yes	Yes	6	0
302	3x30	4x57	Shared	2.77	4.16	No	Yes	No	No	6	7
303	6x61	E3.W334	Shared	2.35	11.74	No	No	No	Yes	3	0
304	3x44	5x50	Shared	1.87	1.87	No	No	Yes	Yes	8	9
305	3x34	4x57	Shared	1.79	1.79	No	No	No	No	6	7
306	5x55	5x56	Shared	1.62	3.23	No	No	No	No	5	5
307	5x55	6x41	Shared	1.62	1.62	No	No	No	No	5	8
308	6x43	7x48	Shared	1.62	1.62	No	No	No	No	7	6
309	5x66	6x34	Shared	1.59	3.17	No	No	No	Yes	5	7
310	3x56	I2x50	Shared	1.53	1.53	Yes	No	No	No	6	8
311	E2.A214	NT.E53	Shared	1.51	3.02	No	No	No	No	0	0
312	3x27	3x30	Shared	1.51	1.51	No	No	No	Yes	5	6
313	8x47	8x49	Shared	1.49	1.49	No	No	No	No	8	7
314	6x61	E3.Q333	Shared	1.37	5.49	No	No	No	No	3	0
315	1x39	7x39	Shared	1.33	4	Yes	Yes	No	No	7	5
316	3x45	4x45	Shared	1.32	5.28	No	No	No	No	7	6
317	E1.H132	NT.D55	Shared	1.26	11.35	Yes	No	No	No	0	0
318	NT.P50	NT.S52	nts1_on	0	7.13	No	No	No	No	0	0
319	E2.G221	NT.S51	nts1_on	0	3.71	No	No	No	No	0	0
320	Lig	NT.L54	nts1_on	0	5.86	Yes	Yes	No	No	0	0
321	E1.H131	NT.V56	nts1_on	0	19.37	No	No	No	No	0	0
322	7x27	NT.V56	nts1_on	0	5.05	No	Yes	No	No	2	0
323	1x32	NT.T58	nts1_on	0	7.51	No	No	No	No	5	0
324	1x28	7x32	nts1_on	0	10.34	No	No	No	No	3	1
325	1x29	1x30	nts1_on	0	3.63	No	No	No	No	2	2
326	1x36	2x66	nts1_on	0	7.28	No	No	Yes	Yes	6	5
327	1x46	7x47	nts1_on	0	3.64	No	No	No	No	8	7
328	1x53	7x54	nts1_on	0	8.77	No	No	No	No	9	7
329	1x55	1x59	nts1_on	0	13.9	No	No	No	No	4	0
330	1x57	2x40	nts1_on	0	5.14	No	No	No	Yes	7	8
331	1x60	I1.S93	nts1_on	0	4.59	No	No	No	No	0	0
332	I1.K92	I1.L94	nts1_on	0	12.69	No	No	No	Yes	0	0
333	2x36	I1.L94	nts1_on	0	5.32	No	No	No	Yes	0	0
334	2x37	I1.L94	nts1_on	0	7.51	No	No	No	Yes	0	0
335	2x40	I1.L94	nts1_on	0	15.43	No	Yes	No	Yes	8	0
336	4x39	I1.Q95	nts1_on	0	11.68	No	No	No	No	3	0
337	2x34	2x36	nts1_on	0	8.66	No	No	No	No	0	0
338	2x35	I2x54	nts1_on	0	5.64	No	No	No	No	0	4
339	2x35	I2x57	nts1_on	0	5.65	No	No	Yes	No	0	7
340	2x36	2x40	nts1_on	0	7.42	No	No	No	Yes	0	8
341	2x37	2x41	nts1_on	0	5.09	No	No	No	No	0	5
342	2x37	4x39	nts1_on	0	9.22	No	No	No	No	0	3
343	2x38	4x42	nts1_on	0	10.99	No	Yes	No	No	7	7
344	2x41	4x39	nts1_on	0	9.26	No	No	No	No	5	3
345	2x41	4x43	nts1_on	0	7.17	No	No	No	No	5	3
346	2x42	4x45	nts1_on	0	4.53	No	Yes	No	No	8	6
347	2x42	4x46	nts1_on	0	5.3	No	Yes	No	No	8	7
348	2x43	7x54	nts1_on	0	5.49	No	No	No	No	8	7
349	2x46	7x53	nts1_on	0	7.03	Yes	No	No	Yes	9	9
350	2x48	4x50	nts1_on	0	3.42	No	No	No	Yes	6	9
351	2x50	3x39	nts1_on	0	7.23	Yes	Yes	No	No	9	9
352	2x53	7x46	nts1_on	0	6.4	No	No	No	No	7	9
353	2x56	3x28	nts1_on	0	4	No	No	Yes	Yes	7	6
354	2x57	2x61	nts1_on	0	5.65	Yes	Yes	No	No	8	6
355	2x57	7x42	nts1_on	0	7.18	Yes	Yes	Yes	No	8	7
356	2x60	2x64	nts1_on	0	4.66	Yes	Yes	No	Yes	6	4
357	2x62	2x67	nts1_on	0	8.83	No	No	No	No	5	5
358	2x63	E1x50	nts1_on	0	9.04	No	No	Yes	Yes	5	8
359	2x63	E1x52	nts1_on	0	4.83	No	No	No	Yes	5	7
360	2x64	3x29	nts1_on	0	5.16	No	Yes	Yes	No	4	4
361	2x64	7x34	nts1_on	0	12.38	No	Yes	Yes	Yes	4	4
362	2x65	2x66	nts1_on	0	3.52	Yes	No	Yes	Yes	4	5
363	E1.H131	Lig	nts1_on	0	3.51	No	No	Yes	Yes	0	0
364	E1x51	E1x52	nts1_on	0	4.16	No	No	No	Yes	3	7
365	3x21	E2.E209	nts1_on	0	4.91	No	No	No	No	8	0
366	3x22	3x26	nts1_on	0	14.29	No	No	No	No	3	7
367	3x32	7x38	nts1_on	0	3.62	Yes	No	Yes	Yes	7	6
368	3x33	5x43	nts1_on	0	4.04	No	No	No	No	5	6
369	3x36	7x41	nts1_on	0	7.78	No	No	No	No	7	7
370	3x37	5x46	nts1_on	0	4.79	No	No	No	No	7	5
371	3x41	4x53	nts1_on	0	4.5	No	No	No	No	6	8
372	3x42	4x49	nts1_on	0	4.25	No	Yes	No	No	8	7
373	3x42	4x50	nts1_on	0	4.52	No	Yes	No	Yes	8	9
374	3x43	7x53	nts1_on	0	5.05	Yes	No	No	Yes	8	9
375	3x46	3x50	nts1_on	0	3.64	No	No	Yes	No	9	9
376	3x46	7x53	nts1_on	0	4.69	No	No	No	Yes	9	9
377	3x50	7x53	nts1_on	0	5.14	Yes	No	No	Yes	9	9
378	3x51	5x57	nts1_on	0	10.55	Yes	Yes	No	No	8	7
379	3x54	5x61	nts1_on	0	4.42	Yes	No	No	No	9	9
380	4x64	4x65	nts1_on	0	7.53	No	Yes	No	Yes	5	6
381	4x65	Lig	nts1_on	0	4.24	No	Yes	Yes	Yes	6	0
382	E2.G208	E2.T227	nts1_on	0	3.64	No	No	No	No	0	0
383	E2.Q210	E2.R212	nts1_on	0	8.18	No	No	No	No	0	0
384	E2.N211	E2.S213	nts1_on	0	7.45	No	Yes	No	No	0	0
385	E2.D215	E2.G216	nts1_on	0	5.03	No	No	No	No	0	0
386	E2x51	E2x52	nts1_on	0	5.25	No	No	No	Yes	4	5
387	5x44	6x56	nts1_on	0	7.37	No	No	No	No	6	6
388	5x45	5x46	nts1_on	0	6.22	No	No	No	No	5	5
389	5x461	6x52	nts1_on	0	6.97	No	No	No	Yes	6	7
390	5x50	6x44	nts1_on	0	5.78	Yes	Yes	Yes	No	9	9
391	5x54	6x41	nts1_on	0	4.61	No	No	No	No	8	8
392	5x61	6x37	nts1_on	0	4.28	No	No	No	No	9	8
393	5x66	5x70	nts1_on	0	3.88	No	No	No	No	5	4
394	5x69	6x31	nts1_on	0	3.92	No	No	No	No	6	5
395	6x32	7x56	nts1_on	0	4.15	No	No	No	No	8	7
396	6x40	7x53	nts1_on	0	7.57	No	No	No	Yes	8	9
397	6x51	6x52	nts1_on	0	6.53	No	Yes	No	Yes	6	7
398	6x51	7x38	nts1_on	0	5.81	No	Yes	Yes	Yes	6	6
399	6x54	6x55	nts1_on	0	7.46	Yes	Yes	No	Yes	5	6
400	6x54	Lig	nts1_on	0	4.86	Yes	Yes	Yes	Yes	5	0
401	6x59	6x60	nts1_on	0	5.38	No	No	No	No	3	5
402	7x26	E3.W334	nts1_on	0	3.42	No	No	No	Yes	1	0
403	7x37	7x38	nts1_on	0	4.39	No	Yes	Yes	Yes	6	6
404	7x49	7x53	nts1_on	0	6.98	No	No	No	Yes	9	9
405	7x55	8x54	nts1_on	0	7.31	No	No	Yes	No	6	7
406	8x48	8x51	nts1_on	0	5.53	No	No	No	No	4	9
407	E2.G221	E2.N211	nts1_on	0	3.39	No	No	No	Yes	0	0
408	1x53	2x47	nts1_on	0	3.36	No	No	No	No	9	9
409	7x45	7x46	nts1_on	0	3.26	No	No	No	No	9	9
410	E2.G220	E2.H218	nts1_on	0	3.18	No	No	No	No	0	0
411	2x38	2x39	nts1_on	0	3.17	No	Yes	No	No	7	8
412	1x54	2x47	nts1_on	0	3.15	No	No	No	No	8	9
413	1x29	1x32	nts1_on	0	2.91	No	No	No	No	2	5
414	1x60	8x53	nts1_on	0	2.91	No	No	No	No	0	6
415	5x65	5x68	nts1_on	0	2.83	No	No	No	No	8	6
416	6x32	6x36	nts1_on	0	2.77	No	No	No	No	8	8
417	E1.H131	NT.T58	nts1_on	0	2.74	No	No	No	No	0	0
418	5x68	5x71	nts1_on	0	2.72	No	No	No	No	6	7
419	1x60	2x40	nts1_on	0	2.62	No	No	No	Yes	0	8
420	3x30	4x59	nts1_on	0	2.62	No	Yes	No	No	6	5
421	6x34	6x38	nts1_on	0	2.62	No	Yes	No	No	7	5
422	7x23	7x25	nts1_on	0	2.59	No	No	No	No	4	2
423	6x57	7x29	nts1_on	0	2.49	No	No	No	No	4	4
424	6x33	6x36	nts1_on	0	1.84	No	No	No	No	8	8
425	1x54	2x44	nts1_on	0	1.71	No	No	No	No	8	6
426	1x57	2x44	nts1_on	0	1.71	No	No	No	No	7	6
427	5x62	6x34	nts1_on	0	1.7	No	No	No	Yes	6	7
428	5x72	6x27	nts1_on	0	1.7	No	No	No	No	5	3
429	4x38	4x40	nts1_on	0	1.63	No	No	No	No	8	4
430	3x53	3x54	nts1_on	0	1.62	No	No	Yes	No	8	9
431	1x44	1x45	nts1_on	0	1.6	No	No	No	No	5	6
432	1x48	1x52	nts1_on	0	1.6	No	No	No	No	5	6
433	5x38	5x42	nts1_on	0	1.6	No	No	No	No	4	5
434	5x52	5x56	nts1_on	0	1.6	No	No	No	No	3	5
435	2x551	3x35	nts1_on	0	1.59	No	No	No	No	5	7
436	4x64	5x39	nts1_on	0	1.59	No	Yes	No	No	5	6
437	3x52	I2x53	nts1_on	0	1.58	No	No	No	No	4	6
438	6x39	7x52	nts1_on	0	1.58	No	No	No	No	7	8
439	6x42	6x46	nts1_on	0	1.54	No	No	No	No	5	6
440	7x51	7x56	nts1_on	0	1.54	No	No	No	No	6	7
441	E2.H218	NT.P50	nts1_on	0	1.53	No	No	No	No	0	0
442	5x72	5x75	nts1_on	0	1.52	No	No	No	No	5	3
443	6x40	7x52	nts1_on	0	1.49	No	No	No	No	8	8
444	7x52	7x56	nts1_on	0	1.49	No	No	No	No	8	7
445	5x63	5x67	nts1_on	0	1.48	No	No	No	No	4	4
446	6x57	6x61	nts1_on	0	1.46	No	No	No	No	4	3
447	5x41	5x42	nts1_on	0	1.43	No	No	No	No	5	5
448	5x65	6x30	nts1_on	0	1.38	No	No	No	No	8	7
449	6x26	6x29	nts1_on	0	1.38	No	No	No	No	4	6
450	E2.N211	E2.Q217	nts1_on	0	1.32	No	Yes	No	No	0	0
451	8x47	8x50	nts1_on	0	1.32	No	No	Yes	Yes	8	8
452	1x43	1x44	nts1_on	0	1.31	No	Yes	No	No	7	5
453	1x33	2x66	nts1_on	0	1.23	No	No	Yes	Yes	6	5
454	6x32	8x51	nts1_on	0	1.13	No	No	No	No	8	9

Orange: nodes, hubs and links specific of nts1_on_allo network

Green: nodes, hubs and links shared by both networks

Purple: nodes, hubs and links specific of nts1_on network

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Owner: the name of the network the hub belong to or "Shared" if the corresponding hub is present in both networks.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub in the corresponding network.

Num Of Links: the number of links of the corresponding hub in the corresponding network.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Owner	nts1_on_allo Avg Int. Strength	nts1_on Avg Int. Strength	nts1_on_allo Num Of Links	nts1_on Num Of Links	ConSurf
1	2x46	nts1_on_allo	5.352	5.98333	5	3	9
2	2x65	nts1_on_allo	7.84	3.52	4	1	4
3	E1.H132	nts1_on_allo	6.565	9.53	4	2	0
4	3x29	nts1_on_allo	9.3275	7.3	4	3	4
5	3x32	nts1_on_allo	7.19	7.39333	4	3	7
6	3x43	nts1_on_allo	4.2175	4.06	4	2	8
7	3x49	nts1_on_allo	11.9525	6.425	4	2	8
8	3x50	nts1_on_allo	13.075	4.39	4	2	9
9	3x54	nts1_on_allo	3.94	3.02	4	2	9
10	3x55	nts1_on_allo	5.8925	4.975	4	2	7
11	3x56	nts1_on_allo	6.542	3.12333	5	3	6
12	I2x57	nts1_on_allo	8.234	3.58	5	2	7
13	5x47	nts1_on_allo	5.6	6.43333	5	3	8
14	5x58	nts1_on_allo	5.005	6.66667	4	3	9
15	6x44	nts1_on_allo	7.698	5.92667	5	3	9
16	7x42	nts1_on_allo	6.72	7.85333	5	3	7
17	8x54	nts1_on_allo	7.36	7.47667	5	3	7
18	Allo3	nts1_on_allo	10.7344	0	9	0	0
19	Lig	Shared	11.1713	9.98312	15	16	0
20	1x39	Shared	6.42	4.985	7	4	7
21	2x50	Shared	8.2775	6.53	4	4	9
22	2x57	Shared	6.81	5.198	4	5	8
23	2x60	Shared	8.03	7.41333	6	6	6
24	2x66	Shared	17.6125	6.1975	4	4	5
25	E1x50	Shared	8.05	10.36	6	5	8
26	3x28	Shared	9.91167	5.988	6	5	6
27	3x51	Shared	7.22	6.212	4	5	8
28	5x50	Shared	4.34	3.93	4	4	9
29	6x48	Shared	8.546	7.238	5	5	8
30	6x54	Shared	9.32167	7.89	6	7	5
31	7x30	Shared	7.518	8.31	5	4	4
32	7x34	Shared	13.1375	9.164	4	5	4
33	7x38	Shared	8.642	6.698	5	5	6
34	8x50	Shared	5.08333	7.23	6	5	8
35	1x43	nts1_on	9.70333	4.3975	3	4	7
36	I1.L94	nts1_on	0	10.2375	0	4	0
37	2x38	nts1_on	10.915	4.975	2	4	7
38	2x40	nts1_on	18.51	7.6525	1	4	8
39	2x42	nts1_on	8.94333	6.0075	3	4	8
40	2x64	nts1_on	15.1033	6.73167	3	6	4
41	E1x52	nts1_on	5.65667	4.89	3	5	7
42	3x30	nts1_on	5.89333	4.8125	3	4	6
43	3x42	nts1_on	7.29333	5.534	3	5	8
44	4x50	nts1_on	5.38	4.836	3	5	9
45	4x64	nts1_on	5.635	4.7725	2	4	5
46	4x65	nts1_on	12.215	8.1525	2	4	6
47	E2.N211	nts1_on	7.35	5.1	2	4	0
48	E2x52	nts1_on	7.74333	6.5975	3	4	5
49	6x34	nts1_on	2.285	2.99	2	4	7
50	6x51	nts1_on	8.92	7.612	3	5	6
51	6x52	nts1_on	8.395	7.5875	2	4	7
52	6x55	nts1_on	7.69	9.6625	3	4	6
53	E3.W334	nts1_on	13.1367	10.1125	3	4	0
54	7x27	nts1_on	15.2467	13.775	3	4	2
55	7x37	nts1_on	8.07333	5.8575	3	4	6
56	7x53	nts1_on	7.56333	6.07667	3	6	9

Orange: nodes, hubs and links specific of nts1_on_allo network

Green: nodes, hubs and links shared by both networks

Purple: nodes, hubs and links specific of nts1_on network

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Owner: the name of the network the link belong to or "Shared" if the corresponding link is present in both networks.

Recurrence: the relative Recurrence in the filtered pool of shortest paths.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Owner	nts1_on_allo Recurrence	nts1_on Recurrence	nts1_on_allo Hub1?	nts1_on Hub1?	nts1_on_allo Hub2?	nts1_on Hub2?	ConSurf1	ConSurf2
1	6x55	Lig	nts1_on_allo	10.0538	8.25551	No	Yes	Yes	Yes	6	0
2	E1.H132	Lig	nts1_on_allo	50.5949	0	Yes	No	Yes	Yes	0	0
3	E1.H132	NT.L54	nts1_on_allo	45.8066	1.49118	Yes	No	No	No	0	0
4	NT.E53	NT.L54	nts1_on_allo	21.1331	0	No	No	No	No	0	0
5	E2.S213	NT.E53	nts1_on_allo	18.3794	0	No	No	No	No	0	0
6	E2.R212	NT.L54	nts1_on_allo	25.2056	0	No	No	No	No	0	0
7	1x36	2x61	nts1_on_allo	11.9595	0	No	No	No	No	6	6
8	1x39	7x38	nts1_on_allo	10.7245	0	Yes	Yes	Yes	Yes	7	6
9	7x34	7x38	nts1_on_allo	36.6749	0.428814	Yes	Yes	Yes	Yes	4	6
10	1x39	2x57	nts1_on_allo	10.5762	2.81971	Yes	Yes	Yes	Yes	7	8
11	7x38	7x42	nts1_on_allo	44.2234	0	Yes	Yes	Yes	No	6	7
12	6x47	7x43	nts1_on_allo	12.024	4.91941	No	No	No	No	9	5
13	6x47	7x45	nts1_on_allo	13.1912	5.61325	No	No	No	No	9	9
14	6x48	7x45	nts1_on_allo	14.352	9.72849	Yes	Yes	No	No	8	9
15	6x44	6x48	nts1_on_allo	79.3248	8.72755	Yes	No	Yes	Yes	9	8
16	3x43	6x44	nts1_on_allo	58.4239	0	Yes	No	Yes	No	8	9
17	3x43	Allo3	nts1_on_allo	67.5717	0	Yes	No	Yes	No	8	0
18	8x50	Allo3	nts1_on_allo	14.4327	0	Yes	Yes	Yes	No	8	0
19	2x39	3x49	nts1_on_allo	11.521	0	No	No	Yes	No	8	8
20	2x39	3x50	nts1_on_allo	12.5431	0	No	No	Yes	No	8	9
21	3x50	Allo3	nts1_on_allo	13.7813	0	Yes	No	Yes	No	9	0
22	2x45	3x42	nts1_on_allo	20.5527	6.95315	No	No	No	Yes	9	8
23	2x49	3x42	nts1_on_allo	13.7523	9.52376	No	No	No	Yes	8	8
24	2x49	3x39	nts1_on_allo	15.9095	9.87522	No	No	No	No	8	9
25	2x45	4x50	nts1_on_allo	11.1115	0.080758	No	No	No	Yes	9	9
26	2x46	3x43	nts1_on_allo	13.0074	0	Yes	No	Yes	No	9	8
27	6x51	6x55	nts1_on_allo	11.6113	9.57949	No	Yes	No	Yes	6	6
28	E2.Q210	E2x51	nts1_on_allo	22.6453	0	No	No	No	No	0	4
29	4x60	4x63	nts1_on_allo	11.5274	9.17115	No	No	No	No	7	4
30	4x64	E2.I228	nts1_on_allo	14.3456	2.63089	No	Yes	No	No	5	0
31	E2.I228	E2.T227	nts1_on_allo	17.138	0	No	No	No	No	0	0
32	3x37	5x43	nts1_on_allo	14.7164	9.03011	No	No	No	No	7	6
33	5x54	5x58	nts1_on_allo	20.8332	0	No	No	Yes	No	8	9
34	5x54	6x44	nts1_on_allo	15.4355	0	No	No	Yes	No	8	9
35	3x54	3x55	nts1_on_allo	20.3689	0	Yes	No	Yes	No	9	7
36	3x54	Allo3	nts1_on_allo	24.5478	0	Yes	No	Yes	No	9	0
37	5x47	6x44	nts1_on_allo	13.0494	0	Yes	No	Yes	No	8	9
38	6x32	6x35	nts1_on_allo	10.5117	0	No	No	No	No	8	7
39	6x35	6x36	nts1_on_allo	12.8075	0	No	No	No	No	7	8
40	6x36	7x56	nts1_on_allo	13.8039	0	No	No	No	No	8	7
41	7x56	Allo3	nts1_on_allo	14.9421	0	No	No	Yes	No	7	0
42	6x54	7x30	nts1_on_allo	10.228	1.16473	Yes	Yes	Yes	Yes	5	4
43	6x54	7x38	nts1_on_allo	17.4443	0	Yes	Yes	Yes	Yes	5	6
44	7x34	Lig	Shared	70.6542	32.0257	Yes	Yes	Yes	Yes	4	0
45	2x60	7x34	Shared	33.5924	35.2662	Yes	Yes	Yes	Yes	6	4
46	6x48	7x41	Shared	99.2745	97.0051	Yes	Yes	No	No	8	7
47	7x41	7x42	Shared	100	97.5932	No	No	Yes	No	7	7
48	2x60	7x42	Shared	44.0331	100	Yes	Yes	Yes	No	6	7
49	3x39	6x48	Shared	16.6898	98.0118	No	No	Yes	Yes	9	8
50	E2.R212	E2x51	Shared	23.8513	42.0863	No	No	No	No	0	4
51	4x63	4x64	Shared	12.9397	10.4724	No	No	No	Yes	4	5
52	E2.Q210	E2.T227	Shared	18.5245	38.2941	No	No	No	No	0	0
53	5x43	6x55	Shared	17.641	14.4216	No	No	No	Yes	6	6
54	3x47	5x57	Shared	10.6762	20.475	No	No	No	No	9	7
55	3x47	5x58	Shared	11.8305	21.4896	No	No	Yes	No	9	9
56	2x60	3x28	Shared	11.7338	12.6267	Yes	Yes	Yes	Yes	6	6
57	E2.H218	NT.S51	nts1_on	2.91813	10.1562	No	No	No	No	0	0
58	E2.G221	NT.S51	nts1_on	0	12.1808	No	No	No	No	0	0
59	4x65	Lig	nts1_on	0	25.2943	No	Yes	Yes	Yes	6	0
60	4x65	E2x52	nts1_on	1.1737	30.7915	No	Yes	No	Yes	6	5
61	E2x51	E2x52	nts1_on	0	44.0745	No	No	No	Yes	4	5
62	E2.Q210	E2.R212	nts1_on	0	40.2869	No	No	No	No	0	0
63	E2.G208	E2.T227	nts1_on	0	36.299	No	No	No	No	0	0
64	3x26	E2.G208	nts1_on	1.46068	34.3017	No	No	No	No	7	0
65	3x22	3x26	nts1_on	0	32.3021	No	No	No	No	3	7
66	3x22	E2.E209	nts1_on	1.46068	30.3002	No	No	No	No	3	0
67	E2.E209	E2.L222	nts1_on	2.77303	26.2896	No	No	No	No	0	0
68	E2.L222	E2.N211	nts1_on	4.36914	24.2809	No	No	No	Yes	0	0
69	E2.G221	E2.N211	nts1_on	0	14.2032	No	No	No	Yes	0	0
70	6x58	Lig	nts1_on	3.79841	16.9319	No	No	Yes	Yes	4	0
71	6x58	E2x52	nts1_on	3.7049	17.2151	No	No	No	Yes	4	5
72	E1.H131	Lig	nts1_on	0	10.2904	No	No	Yes	Yes	0	0
73	2x57	7x42	nts1_on	0	10.4064	Yes	Yes	Yes	No	8	7
74	2x60	2x64	nts1_on	0	45.5521	Yes	Yes	No	Yes	6	4
75	2x64	3x29	nts1_on	0	11.2891	No	Yes	Yes	No	4	4
76	3x29	4x65	nts1_on	2.10879	21.7159	Yes	No	No	Yes	4	6
77	3x28	3x29	nts1_on	4.83346	11.0365	Yes	Yes	Yes	No	6	4
78	2x64	Lig	nts1_on	2.95038	33.4224	No	Yes	Yes	Yes	4	0
79	2x50	3x39	nts1_on	0	87.9079	Yes	Yes	No	No	9	9
80	7x54	8x50	nts1_on	1.17693	22.0708	No	No	Yes	Yes	7	8
81	2x43	7x54	nts1_on	0	28.3699	No	No	No	No	8	7
82	2x43	3x46	nts1_on	1.1608	29.3914	No	No	No	No	8	9
83	3x46	7x53	nts1_on	0	30.3366	No	No	No	Yes	9	9
84	2x46	7x53	nts1_on	0	45.3587	Yes	No	No	Yes	9	9
85	2x46	2x50	nts1_on	7.53233	43.6457	Yes	No	Yes	Yes	9	9
86	7x49	7x53	nts1_on	0	43.2033	No	No	No	Yes	9	9
87	2x50	7x49	nts1_on	0.596524	43.5786	Yes	Yes	No	No	9	9
88	1x56	8x50	nts1_on	2.26034	14.9163	No	No	Yes	Yes	7	8
89	1x60	2x40	nts1_on	0	10.7101	No	No	No	Yes	0	8
90	1x60	8x53	nts1_on	0	12.8155	No	No	No	No	0	6
91	1x56	8x53	nts1_on	1.20272	13.8676	No	No	No	No	7	6
92	4x64	4x65	nts1_on	0	15.6545	No	Yes	No	Yes	5	6
93	3x43	7x53	nts1_on	0	50.9458	Yes	No	No	Yes	8	9
94	5x58	6x41	nts1_on	5.99426	45.08	Yes	No	No	No	9	8
95	5x54	6x41	nts1_on	0	49.0019	No	No	No	No	8	8
96	3x43	5x54	nts1_on	6.49083	49.9767	Yes	No	No	No	8	8
97	3x51	5x57	nts1_on	0	18.4481	Yes	Yes	No	No	8	7
98	3x51	5x61	nts1_on	1.20595	18.6505	Yes	Yes	No	No	8	9
99	5x61	6x37	nts1_on	0	21.5999	No	No	No	No	9	8
100	5x58	6x37	nts1_on	2.41512	22.6168	Yes	No	No	No	9	8
101	3x51	3x55	nts1_on	3.52755	26.7468	Yes	Yes	Yes	No	8	7
102	3x55	5x64	nts1_on	6.87776	24.6721	Yes	No	No	No	7	5
103	5x64	5x68	nts1_on	5.83949	22.6896	No	No	No	No	5	6
104	5x65	5x68	nts1_on	0	18.5334	No	No	No	No	8	6
105	5x65	6x34	nts1_on	3.52433	10.378	No	No	No	Yes	8	7
106	6x40	7x53	nts1_on	0	10.6339	No	No	No	Yes	8	9

Here, those paths that begin and end at given residue pair(s) or that pass through a residue are used to generate a novel metapath. Such a path filtering is particularly recommended if some information on allosteric residues is available. The selection syntax for a residue pair ("Pairs") is C:C:c534,A:A:?600 (the lower-case "c" stands for cytosine and "?" indicates any non standard amino acid or nucleotide residue). Selection of more than one apical residue pair has the following syntax: C:C:c534,A:A:?600,C:C:c534,A:A:E41. Only one residue can be selected as a tail ("Tail"). For midway residue(s), each residue must be separated by a comma as well e.g. A:A:?600,A:A:E41.

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Node1	Node2	Owner	Net1LinkStrength	Net2LinkStrength	Comm1	Comm2	Node1Shell	Node2Shell
E1.H132	NT.L54	Shared	7.71	3.86	0	1	1	1
Lig	NT.L54	nts1_on	5.86	0	1	1	0	1
E1.H132	NT.D55	Shared	11.35	1.26	0	1	1	2
E1.H131	NT.V56	nts1_on	19.37	0	1	3	1	2
7x27	NT.V56	nts1_on	5.05	0	1	1	1	2
7x31	NT.V56	Shared	16.61	12.45	1	0	2	2
2x60	2x64	nts1_on	4.66	0	1	1	2	1
2x60	3x28	Shared	4.49	6.73	1	1	2	2
2x60	7x34	Shared	5.61	8.98	1	1	2	1
2x60	7x38	Shared	9.2	10.52	1	1	2	2
2x62	2x67	nts1_on	8.83	0	0	3	2	2
2x64	E1x50	Shared	4.01	21.05	1	1	1	2
2x64	3x28	Shared	4.13	15.47	1	1	1	2
2x64	3x29	nts1_on	5.16	0	1	1	1	1
2x64	7x34	nts1_on	12.38	0	1	1	1	1
2x64	Lig	Shared	10.05	8.79	1	1	1	0
E1.H131	Lig	nts1_on	3.51	0	1	3	1	0
3x28	3x29	Shared	5.96	9.93	1	1	2	1
3x29	4x65	Shared	10.78	14.37	1	1	1	1
4x64	4x65	nts1_on	7.53	0	0	0	2	1
4x65	E2x52	Shared	10.06	10.06	1	0	1	2
4x65	Lig	nts1_on	4.24	0	1	0	1	0
E2.V223	Lig	Shared	15.14	6.31	0	0	1	0
6x58	E2x52	Shared	5.78	4.33	1	1	1	2
5x40	6x59	Shared	8.18	6.55	1	1	1	2
5x40	Lig	Shared	5.71	2.85	1	1	1	0
5x43	6x55	Shared	14.46	3.62	0	0	2	1
6x51	6x54	Shared	8.23	9.26	1	0	2	1
6x51	6x55	Shared	8.23	13.38	1	0	2	1
6x51	7x38	nts1_on	5.81	0	1	0	2	2
6x54	6x55	nts1_on	7.46	0	1	1	1	1
6x54	7x30	Shared	11.32	7.2	1	1	1	1
6x54	7x33	Shared	4.28	7.48	1	1	1	2
6x54	7x34	Shared	11.32	15.43	1	1	1	1
6x54	7x37	Shared	7.76	12.94	1	1	1	2
6x54	Lig	nts1_on	4.86	0	1	1	1	0
6x55	Lig	Shared	8.5	6.07	1	1	1	0
6x58	7x30	Shared	6.19	8.25	1	1	1	1
6x58	Lig	Shared	17.32	12.94	1	1	1	0
6x61	E3.W334	Shared	11.74	2.35	0	0	2	1
7x26	E3.W334	nts1_on	3.42	0	0	0	2	1
7x30	E3.W334	Shared	4.82	5.79	1	1	1	1
E3.W334	Lig	Shared	20.47	31.27	1	1	1	0
7x23	7x24	Shared	3.5	5.25	0	0	2	1
7x23	7x26	Shared	8.84	4.42	0	0	2	2
7x27	7x31	Shared	18.51	18.51	1	1	1	2
7x27	Lig	Shared	29.24	21.48	1	1	1	0
7x30	Lig	Shared	10.91	10.91	1	1	1	0
7x33	7x37	Shared	7.78	7.78	1	1	2	2
7x34	7x38	Shared	10.47	18.61	1	1	1	2
7x34	Lig	Shared	6.04	9.53	1	1	1	0
7x37	7x38	nts1_on	4.39	0	1	1	2	2
E1.H131	NT.T58	nts1_on	2.74	0	1	3	1	2
7x27	7x28	Shared	2.3	5.75	1	1	1	2
5x33	Lig	Shared	1.5	5.17	0	1	1	0
7x24	Lig	nts1_on_allo	0	7.21	0	1	1	0
E1.H132	Lig	nts1_on_allo	0	4.36	0	1	1	0
3x29	Lig	nts1_on_allo	0	9.42	1	1	1	0
E2.R212	NT.L54	nts1_on_allo	0	4.86	0	0	2	1
NT.T58	NT.V56	nts1_on_allo	0	6.35	0	0	2	2
2x62	2x66	nts1_on_allo	0	15.43	0	3	2	2
2x62	E1.H131	nts1_on_allo	0	8.71	0	3	2	1
2x66	2x67	nts1_on_allo	0	12.26	0	3	2	2
2x66	E1.H131	nts1_on_allo	0	13.75	0	3	2	1
2x67	E1.H131	nts1_on_allo	0	4.15	0	3	2	1
E1.H132	E1x49	nts1_on_allo	0	16.78	0	1	1	2
3x28	E1x50	nts1_on_allo	0	8.68	1	1	2	2
6x54	7x38	nts1_on_allo	0	3.62	1	1	1	2
7x30	7x31	nts1_on_allo	0	5.44	1	1	1	2
3x29	4x61	nts1_on_allo	0	3.59	1	1	1	2
NT.E53	NT.L54	nts1_on_allo	0	2.65	0	0	2	1
5x32	5x33	nts1_on_allo	0	1.37	0	0	2	1

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Difference Members
	Id	Description
	nts1_on_allo	8JPB-NTS₁-Neurotensin 8-13-PubChem 118610427; GDP; Mg-Gq; GRK2
	nts1_on	6OS9-NTS₁-JMV449-Gi1/&β;1/&γ;2

Network Difference
Value	nts1_on_allo	nts1_on
I_min	3.62	3.42
Number of Linked Nodes	281	281
Number of Specific Nodes	23 (8.19%)	23 (8.19%)
Number of Shared Nodes	258 (91.81%)	258 (91.81%)
Number of Links	317	309
Number of Specific Links	145 (45.74%)	137 (44.34%)
Number of Shared Links	172 (54.26%)	172 (55.66%)
Number of Hubs	34	38
Number of Specific Hubs	18 (52.94%)	22 (57.89%)
Number of Shared Hubs	16 (47.06%)	16 (42.11%)
Average % Shared Neighbours (Jaccard)	39.24
Average % Shared Neighbours (Otsuka)	47.26
Average % Shared Neighbours (Overlap Coefficient)	54.56
Average % Shared Cliques (k3-6)	78.26
Graphlets Similarity	0.545231

Paths Difference
Value	nts1_on_allo	nts1_on
Number Of Nodes in MetaPath	57	59
Specific Nodes in MetaPath	32 (56.14%)	34 (57.63%)
Shared Nodes in MetaPath	258 (91.81%)	258 (91.81%)
Number Of Links MetaPath	56	63
Specific Links in MetaPath	43 (76.79%)	50 (79.37%)
Shared Links in MetaPath	172 (54.26%)	172 (54.26%)
Number of Shortest Paths	55721	122074
Length Of Smallest Path	3	3
Average Path Length	13.0216	19.3482
Length of Longest Path	34	41
Minimum Path Strength	1.465	1.28
Average Path Strength	7.27501	6.74773
Maximum Path Strength	23.105	23.875
Minimum Path Correlation	0.7	0.7
Average Path Correlation	0.923888	0.931475
Maximum Path Correlation	0.99	0.99
Minimum % Of Corr. Nodes	4	3.84615
Average % Of Corr. Nodes	52.988	41.8708
Maximum % Of Corr. Nodes	100	100
Minimum Path Hubs %	0	0
Average Path Hubs %	46.2752	36.19
Maximum Path Hubs %	100	100

Details about the values in these tables can be found in the corresponding documentation page .

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