psnGPCR

Press and hold down the left mouse button and move the mouse to rotate.
Press and hold down the central mouse button and move the mouse to translate.
Use the mouse wheel to zoom in or out.
Click on any atom on your molecule and the corresponding residue label will be placed beneath the viewer.

Orange: nodes, hubs and links specific of nucleotide_off network

Green: nodes, hubs and links shared by both networks

Purple: nodes, hubs and links specific of nucleotide_on network

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Owner: the name of the network the link belong to or "Shared" if the corresponding link is present in both networks.

Strength: the interaction strength between the two nodes or 0 if the link is not present.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Owner	nucleotide_off Int. Strength	nucleotide_on Int. Strength	nucleotide_off Hub1?	nucleotide_on Hub1?	nucleotide_off Hub2?	nucleotide_on Hub2?	ConSurf1	ConSurf2
1	1x36	2x65	nucleotide_off	100	0	No	No	No	No	5	4
2	1x39	2x60	nucleotide_off	100	0	Yes	Yes	No	No	6	7
3	1x51	2x51	nucleotide_off	100	0	No	No	Yes	No	5	7
4	1x55	8x57	nucleotide_off	100	0	Yes	No	No	No	4	7
5	1x57	2x40	nucleotide_off	100	0	No	Yes	No	Yes	8	8
6	2x38	3x49	nucleotide_off	100	0	No	No	Yes	Yes	6	9
7	2x39	3x50	nucleotide_off	100	0	No	No	Yes	No	8	9
8	2x42	4x46	nucleotide_off	100	0	Yes	Yes	No	No	8	8
9	2x43	7x53	nucleotide_off	100	0	No	No	Yes	No	8	9
10	2x53	2x56	nucleotide_off	100	0	No	No	No	No	8	6
11	2x53	3x35	nucleotide_off	100	0	No	No	No	Yes	8	7
12	2x54	2x57	nucleotide_off	100	0	No	No	Yes	No	7	6
13	2x63	E2x50	nucleotide_off	100	0	Yes	No	Yes	No	3	9
14	E1x51	E2	nucleotide_off	100	0	No	No	Yes	Yes	4	3
15	3x22	3x26	nucleotide_off	100	0	No	No	No	No	3	5
16	3x23	E2	nucleotide_off	100	0	No	No	Yes	Yes	1	3
17	3x32	3x33	nucleotide_off	100	0	No	No	No	No	6	4
18	3x33	4x60	nucleotide_off	100	0	No	No	No	No	4	4
19	3x36	6x48	nucleotide_off	100	0	No	No	Yes	Yes	6	8
20	3x37	4x56	nucleotide_off	100	0	Yes	No	No	No	6	5
21	3x44	5x54	nucleotide_off	100	0	No	No	No	No	7	8
22	3x49	I2x57	nucleotide_off	100	0	Yes	Yes	No	No	9	7
23	3x50	3x53	nucleotide_off	100	0	Yes	No	No	No	9	8
24	3x50	6x30	nucleotide_off	100	0	Yes	No	No	No	9	6
25	3x50	6x33	nucleotide_off	100	0	Yes	No	No	No	9	7
26	3x51	5x61	nucleotide_off	100	0	Yes	No	No	No	7	9
27	3x52	I2x57	nucleotide_off	100	0	No	No	No	No	5	7
28	5x37	6x59	nucleotide_off	100	0	No	No	No	Yes	3	4
29	5x39	5x43	nucleotide_off	100	0	Yes	Yes	No	No	6	5
30	5x42	5x461	nucleotide_off	100	0	No	No	Yes	No	5	8
31	5x51	6x45	nucleotide_off	100	0	No	Yes	No	No	6	6
32	5x68	6x27	nucleotide_off	100	0	No	No	No	No	7	1
33	6x33	8x49	nucleotide_off	100	0	No	No	No	No	7	6
34	6x44	7x45	nucleotide_off	100	0	No	No	Yes	No	9	9
35	6x58	Lig	nucleotide_off	100	0	No	No	Yes	Yes	4	0
36	7x49	7x53	nucleotide_off	100	0	Yes	Yes	Yes	No	9	9
37	1x31	7x35	nucleotide_off	100	0	No	No	Yes	No	4	3
38	1x58	1x59	nucleotide_off	100	0	No	No	No	No	3	5
39	3x52	I2x56	nucleotide_off	100	0	No	No	No	No	5	4
40	5x37	5x41	nucleotide_off	100	0	No	No	No	No	3	4
41	7x31	Lig	nucleotide_off	100	0	Yes	No	Yes	Yes	3	0
42	8x49	8x52	nucleotide_off	100	0	No	No	No	No	6	4
43	7x35	7x38	nucleotide_off	100	0	Yes	No	Yes	No	3	5
44	1x47	2x51	nucleotide_off	100	0	No	No	Yes	No	6	7
45	2x63	E1x50	nucleotide_off	100	0	Yes	No	No	No	3	3
46	Lig	NT	nucleotide_off	100	0	Yes	Yes	Yes	No	0	0
47	7x31	NT	nucleotide_off	100	0	Yes	No	Yes	No	3	0
48	E1	NT	nucleotide_off	100	0	Yes	Yes	Yes	No	0	0
49	1x30	1x35	nucleotide_off	100	0	No	No	Yes	Yes	5	5
50	1x30	7x36	nucleotide_off	100	0	No	No	No	No	5	3
51	1x31	7x31	nucleotide_off	100	0	No	No	Yes	No	4	3
52	1x32	E1	nucleotide_off	100	0	No	Yes	Yes	Yes	4	0
53	I1	I1	nucleotide_off	100	0	Yes	No	Yes	No	0	0
54	2x44	I1	nucleotide_off	100	0	Yes	No	Yes	No	5	0
55	2x37	8x48	nucleotide_off	100	0	No	No	No	No	7	4
56	2x56	3x28	nucleotide_off	100	0	No	No	No	No	6	6
57	2x63	E1	nucleotide_off	100	0	Yes	No	Yes	Yes	3	0
58	3x29	E2x50	nucleotide_off	100	0	No	No	Yes	No	4	9
59	3x30	3x34	nucleotide_off	100	0	No	No	Yes	Yes	6	5
60	3x36	3x37	nucleotide_off	100	0	No	No	Yes	No	6	6
61	3x37	6x52	nucleotide_off	100	0	Yes	No	No	No	6	7
62	4x63	5x36	nucleotide_off	100	0	Yes	No	No	No	5	5
63	7x38	E2x52	nucleotide_off	100	0	Yes	No	Yes	No	5	4
64	5x33	6x62	nucleotide_off	100	0	No	No	No	No	0	0
65	5x34	6x63	nucleotide_off	100	0	No	No	No	No	0	0
66	6x36	7x55	nucleotide_off	100	0	No	No	No	No	8	6
67	7x23	E3	nucleotide_off	100	0	No	No	No	Yes	0	3
68	6x54	7x33	nucleotide_off	51.9231	0	Yes	No	No	No	4	4
69	3x54	6x30	nucleotide_off	50	0	Yes	No	No	No	9	6
70	4x62	4x63	nucleotide_off	50	0	No	No	Yes	No	4	5
71	6x29	8x52	nucleotide_off	50	0	No	No	No	No	6	4
72	1x53	7x53	nucleotide_off	50	0	No	No	Yes	No	9	9
73	1x36	2x64	nucleotide_off	50	0	No	No	No	No	5	3
74	4x39	I1	nucleotide_off	50	0	No	No	Yes	No	3	0
75	2x44	2x48	nucleotide_off	50	0	Yes	No	No	No	5	6
76	8x50	I1x50	nucleotide_off	50	0	Yes	Yes	No	No	9	8
77	2x51	2x55	nucleotide_off	50	0	Yes	No	No	No	7	4
78	2x46	7x53	nucleotide_off	50	0	No	Yes	Yes	No	9	9
79	6x40	7x49	nucleotide_off	50	0	No	No	Yes	Yes	8	9
80	3x37	4x53	nucleotide_off	50	0	Yes	No	No	No	6	8
81	I2x51	I2x52	nucleotide_off	51.9231	0	No	No	No	No	6	5
82	3x34	4x53	nucleotide_off	50	0	Yes	Yes	No	No	5	8
83	4x63	5x35	nucleotide_off	50	0	Yes	No	No	No	5	0
84	3x54	5x65	nucleotide_off	50	0	Yes	No	No	No	9	8
85	2x46	3x39	nucleotide_off	18.2692	0	No	Yes	No	No	9	9
86	3x46	6x37	nucleotide_off	50	0	No	No	No	No	9	8
87	1x33	E1	nucleotide_off	50	0	No	No	Yes	Yes	5	0
88	1x42	2x57	nucleotide_off	12.5	0	No	No	Yes	No	7	6
89	5x41	6x56	nucleotide_off	50	0	No	No	No	No	4	5
90	7x23	7x27	nucleotide_off	50	0	No	No	No	No	0	0
91	8x50	8x54	nucleotide_off	50	0	Yes	Yes	No	Yes	9	7
92	5x62	5x66	nucleotide_off	27.8846	0	No	No	No	Yes	6	5
93	7x30	7x32	nucleotide_off	50	0	No	No	No	No	4	1
94	2x66	E1x49	nucleotide_off	50	0	No	No	No	No	3	0
95	1x54	2x51	nucleotide_off	0	0	No	No	Yes	No	7	7
96	5x38	E2	nucleotide_off	50	0	No	No	Yes	Yes	3	3
97	3x29	4x64	nucleotide_off	50	0	No	No	No	No	4	0
98	7x52	7x56	nucleotide_off	0.961538	0	No	No	No	No	8	7
99	3x43	6x44	nucleotide_off	50	0	No	No	No	No	8	9
100	4x38	4x40	nucleotide_off	50	0	No	No	No	No	8	5
101	5x69	6x27	nucleotide_off	50	0	No	Yes	No	No	4	1
102	6x26	6x30	nucleotide_off	50	0	No	No	No	No	3	6
103	8x58	8x63	nucleotide_off	50	0	No	No	No	No	5	4
104	4x47	4x51	nucleotide_off	50	0	No	No	No	No	4	4
105	7x26	7x27	nucleotide_off	50	0	No	No	No	No	0	0
106	5x61	6x34	nucleotide_off	0	0	No	No	No	No	9	7
107	6x54	7x34	nucleotide_off	50	0	Yes	No	Yes	No	4	4
108	6x50	7x37	nucleotide_off	0	0	No	No	No	No	9	5
109	4x39	4x43	nucleotide_off	50	0	No	No	No	No	3	1
110	5x63	5x67	nucleotide_off	25	0	No	No	No	No	4	4
111	5x33	6x63	nucleotide_off	0	0	No	No	No	No	0	0
112	1x46	7x47	nucleotide_off	12.5	0	No	No	No	No	8	6
113	1x56	1x60	nucleotide_off	0	0	No	No	Yes	Yes	8	6
114	2x551	2x59	nucleotide_off	50	0	No	No	No	No	5	5
115	8x55	8x59	nucleotide_off	50	0	No	No	No	No	5	4
116	3x41	4x52	nucleotide_off	50	0	No	No	No	No	4	4
117	6x39	7x56	nucleotide_off	50	0	No	No	No	No	6	7
118	1x55	8x61	nucleotide_off	50	0	Yes	No	No	No	4	6
119	I2x50	I2x51	nucleotide_off	0	0	No	No	No	No	8	6
120	5x62	6x34	nucleotide_off	50	0	No	No	No	No	6	7
121	8x51	8x55	nucleotide_off	50	0	No	No	No	No	8	5
122	7x45	7x48	nucleotide_off	50	0	Yes	No	No	No	9	6
123	4x38	4x39	nucleotide_off	26.9231	0	No	No	No	No	8	3
124	6x53	6x54	nucleotide_off	0	0	No	No	Yes	No	6	4
125	6x57	7x30	nucleotide_off	0	0	No	No	No	No	4	4
126	7x40	7x43	nucleotide_off	0.961538	0	No	No	No	No	7	5
127	5x69	6x24	nucleotide_off	15.3846	0	No	Yes	Yes	No	4	2
128	6x42	6x46	nucleotide_off	25	0	No	No	No	No	5	6
129	4x48	4x52	nucleotide_off	0	0	No	No	No	No	1	4
130	5x68	6x31	nucleotide_off	0	0	No	No	No	No	7	5
131	3x44	3x48	nucleotide_off	25	0	No	No	No	No	7	6
132	2x50	Na1	nucleotide_off	25	0	Yes	Yes	No	No	9	0
133	1x27	1x30	nucleotide_off	25	0	No	No	No	No	0	5
134	I2x54	I2x55	nucleotide_off	0.961538	0	No	No	No	No	4	5
135	5x55	5x59	nucleotide_off	9.61539	0	No	No	No	No	5	3
136	6x25	6x29	nucleotide_off	14.4231	0	No	No	No	No	3	6
137	8x56	8x60	nucleotide_off	13.4615	0	No	No	No	No	5	6
138	5x56	5x59	nucleotide_off	7.69231	0	No	No	No	No	4	3
139	2x41	I1x51	nucleotide_off	7.69231	0	No	No	No	No	4	7
140	6x21	6x24	nucleotide_off	4.80769	0	No	No	Yes	No	0	2
141	1x55	8x62	nucleotide_off	0	0	Yes	No	No	No	4	3
142	1x29	1x33	nucleotide_off	0	0	No	No	No	No	6	5
143	1x27	1x28	nucleotide_off	0	0	No	No	No	No	0	0
144	1x52	8x58	nucleotide_off	0	0	No	No	No	No	7	5
145	4x44	4x47	nucleotide_off	0	0	No	No	No	No	3	4
146	4x51	4x55	nucleotide_off	0	0	No	No	No	No	4	4
147	5x72	6x24	nucleotide_off	1.92308	0	No	No	Yes	No	0	2
148	6x21	6x22	nucleotide_off	1.92308	0	No	No	No	No	0	3
149	5x70	5x73	nucleotide_off	0	0	No	No	No	No	0	0
150	6x23	6x26	nucleotide_off	0.961538	0	No	No	No	No	4	3
151	8x59	8x64	nucleotide_off	0.961538	0	No	No	No	No	4	5
152	1x35	1x39	Shared	100	100	Yes	Yes	Yes	Yes	5	6
153	1x35	2x64	Shared	100	100	Yes	Yes	No	No	5	3
154	1x35	7x35	Shared	100	100	Yes	Yes	Yes	No	5	3
155	1x39	2x57	Shared	100	100	Yes	Yes	Yes	No	6	6
156	1x39	7x39	Shared	100	100	Yes	Yes	No	No	6	5
157	1x39	7x42	Shared	100	100	Yes	Yes	No	No	6	7
158	1x40	2x61	Shared	100	54.1667	No	No	No	No	4	6
159	1x43	2x57	Shared	100	100	No	Yes	Yes	No	5	6
160	1x47	1x51	Shared	100	0	No	No	No	No	6	5
161	1x49	7x50	Shared	100	16.6667	No	No	No	No	8	9
162	1x50	2x50	Shared	100	100	No	Yes	Yes	Yes	9	9
163	1x50	7x50	Shared	100	100	No	Yes	No	No	9	9
164	1x52	8x54	Shared	100	66.6667	No	No	No	Yes	7	7
165	1x55	1x59	Shared	100	100	Yes	No	No	No	4	5
166	1x57	2x44	Shared	100	100	No	Yes	Yes	No	8	5
167	1x60	I1x50	Shared	100	50	Yes	Yes	No	No	6	8
168	2x40	I1x50	Shared	100	100	No	Yes	No	No	8	8
169	2x37	2x40	Shared	100	100	No	No	No	Yes	7	8
170	2x39	3x49	Shared	100	100	No	No	Yes	Yes	8	9
171	2x42	3x45	Shared	100	100	Yes	Yes	No	No	8	7
172	2x42	3x46	Shared	100	66.6667	Yes	Yes	No	No	8	9
173	2x42	4x45	Shared	100	20.8333	Yes	Yes	No	No	8	5
174	2x45	3x42	Shared	100	100	No	No	No	Yes	9	8
175	2x45	4x46	Shared	100	100	No	No	No	No	9	8
176	2x45	4x50	Shared	100	100	No	No	Yes	Yes	9	9
177	2x50	7x46	Shared	100	100	Yes	Yes	No	No	9	9
178	2x50	7x49	Shared	100	100	Yes	Yes	Yes	Yes	9	9
179	2x53	7x46	Shared	100	100	No	No	No	No	8	9
180	2x59	3x28	Shared	100	100	No	No	No	No	5	6
181	3x22	E2	Shared	100	100	No	No	Yes	Yes	3	3
182	3x25	E2	Shared	100	50	No	No	Yes	Yes	9	3
183	3x25	E2x50	Shared	100	100	No	No	Yes	No	9	9
184	3x26	E2	Shared	100	100	No	No	Yes	Yes	5	3
185	3x29	E2x52	Shared	100	100	No	No	Yes	No	4	4
186	3x30	4x61	Shared	100	100	No	No	No	No	6	5
187	3x34	4x54	Shared	100	100	Yes	Yes	No	No	5	3
188	3x37	5x461	Shared	100	100	Yes	No	Yes	No	6	8
189	3x38	4x50	Shared	100	100	No	No	Yes	Yes	7	9
190	3x41	4x49	Shared	100	100	No	No	No	No	4	7
191	3x47	5x54	Shared	100	100	No	No	No	No	9	8
192	3x47	5x58	Shared	100	100	No	No	Yes	Yes	9	9
193	3x49	I2x53	Shared	100	100	Yes	Yes	Yes	Yes	9	7
194	3x51	3x55	Shared	100	100	Yes	No	No	No	7	7
195	3x51	5x60	Shared	100	100	Yes	No	No	No	7	4
196	3x53	I2x53	Shared	100	100	No	No	Yes	Yes	8	7
197	3x55	3x56	Shared	100	100	No	No	No	Yes	7	6
198	3x56	I2x52	Shared	100	100	No	Yes	No	No	6	5
199	I2x53	I2x57	Shared	100	100	Yes	Yes	No	No	7	7
200	4x38	4x41	Shared	100	100	No	No	No	No	8	5
201	4x56	5x461	Shared	100	100	No	No	Yes	No	5	8
202	4x59	5x39	Shared	100	100	No	No	Yes	Yes	6	6
203	4x60	5x39	Shared	100	100	No	No	Yes	Yes	4	6
204	4x63	E2	Shared	100	33.3333	Yes	No	Yes	Yes	5	3
205	5x36	E2	Shared	100	100	No	No	Yes	Yes	5	3
206	5x39	E2	Shared	100	100	Yes	Yes	Yes	Yes	6	3
207	E2	E2	Shared	100	100	Yes	Yes	Yes	Yes	3	3
208	E2	E2x51	Shared	100	100	Yes	Yes	No	No	3	4
209	E2	E2x52	Shared	100	100	Yes	Yes	Yes	No	3	4
210	E2x52	Lig	Shared	100	100	Yes	No	Yes	Yes	4	0
211	E2	Lig	Shared	100	100	Yes	Yes	Yes	Yes	3	0
212	5x39	5x42	Shared	100	100	Yes	Yes	No	No	6	5
213	5x40	6x55	Shared	100	100	No	Yes	No	No	5	5
214	5x44	5x48	Shared	100	100	No	No	No	No	5	5
215	5x44	6x52	Shared	100	100	No	No	No	No	5	7
216	5x47	6x52	Shared	100	100	No	No	No	No	5	7
217	5x49	5x50	Shared	100	100	No	No	No	No	4	8
218	5x58	6x37	Shared	100	50	Yes	Yes	No	No	9	8
219	5x58	6x38	Shared	100	50	Yes	Yes	No	No	9	6
220	5x58	6x41	Shared	100	100	Yes	Yes	No	No	9	8
221	5x65	6x31	Shared	100	50	No	No	No	No	8	5
222	6x36	7x56	Shared	100	50	No	No	No	No	8	7
223	6x40	7x52	Shared	100	50	No	No	No	No	8	8
224	6x44	6x48	Shared	100	100	No	No	Yes	Yes	9	8
225	6x47	7x45	Shared	100	100	No	No	Yes	No	8	9
226	6x48	7x41	Shared	100	100	Yes	Yes	No	No	8	7
227	6x48	7x45	Shared	100	100	Yes	Yes	Yes	No	8	9
228	6x51	Lig	Shared	100	100	No	Yes	Yes	Yes	6	0
229	6x54	7x37	Shared	100	33.3333	Yes	No	No	No	4	5
230	6x55	Lig	Shared	100	100	No	No	Yes	Yes	5	0
231	6x59	6x60	Shared	100	50	No	Yes	No	No	4	4
232	6x61	E3	Shared	100	100	No	No	No	Yes	4	3
233	7x31	7x35	Shared	100	100	Yes	No	Yes	No	3	3
234	7x34	7x38	Shared	100	100	Yes	No	Yes	No	4	5
235	7x34	Lig	Shared	100	100	Yes	No	Yes	Yes	4	0
236	7x38	Lig	Shared	100	100	Yes	No	Yes	Yes	5	0
237	E1x50	E1x52	Shared	100	100	No	No	No	No	3	7
238	5x54	5x58	Shared	100	100	No	No	Yes	Yes	8	9
239	7x45	7x49	Shared	100	100	Yes	No	Yes	Yes	9	9
240	E1x50	E2x50	Shared	100	100	No	No	Yes	No	3	9
241	E3	NT	Shared	100	50	No	Yes	Yes	No	3	0
242	7x24	NT	Shared	100	50	No	No	Yes	No	0	0
243	7x28	NT	Shared	100	100	No	No	Yes	No	0	0
244	1x57	I1	Shared	100	50	No	Yes	Yes	No	8	0
245	2x62	2x66	Shared	100	50	No	No	No	No	4	3
246	2x63	2x64	Shared	100	100	Yes	No	No	No	3	3
247	E1x49	E2	Shared	100	100	No	No	Yes	Yes	0	3
248	E1x51	E1x52	Shared	100	50	No	No	No	No	4	7
249	3x40	6x48	Shared	100	100	No	No	Yes	Yes	8	8
250	3x42	4x49	Shared	100	100	No	Yes	No	No	8	7
251	3x42	4x50	Shared	100	100	No	Yes	Yes	Yes	8	9
252	6x45	6x48	Shared	100	50	No	No	Yes	Yes	6	8
253	6x58	7x34	Shared	100	100	No	No	Yes	No	4	4
254	6x60	6x64	Shared	100	50	No	No	No	No	4	0
255	6x62	Lig	Shared	100	100	No	No	Yes	Yes	0	0
256	8x50	8x51	Shared	100	16.6667	Yes	Yes	No	No	9	8
257	5x46	5x461	Shared	50	100	No	No	Yes	No	5	8
258	1x38	7x39	Shared	50	100	No	No	No	No	5	5
259	1x45	7x47	Shared	50	37.5	No	No	No	No	4	6
260	1x43	2x58	Shared	50	100	No	Yes	No	No	5	8
261	3x51	5x57	Shared	51.9231	100	Yes	No	No	No	7	6
262	1x39	2x61	Shared	50	50	Yes	Yes	No	No	6	6
263	2x42	4x42	Shared	50	100	Yes	Yes	No	Yes	8	7
264	5x411	6x59	Shared	50	50	No	No	No	Yes	4	4
265	3x40	5x50	Shared	50	58.3333	No	No	No	No	8	8
266	3x38	4x53	Shared	50	100	No	No	No	No	7	8
267	5x44	5x45	Shared	50	100	No	No	No	No	5	4
268	3x27	3x31	Shared	25	66.6667	No	No	No	No	4	4
269	5x37	6x55	Shared	50	50	No	No	No	No	3	5
270	1x42	7x47	Shared	50	33.3333	No	No	No	No	7	6
271	3x21	E2	Shared	50	50	No	No	Yes	Yes	6	3
272	3x24	E1x52	Shared	50	33.3333	No	No	No	No	5	7
273	5x60	5x63	Shared	62.5	50	No	No	No	No	4	4
274	1x33	1x34	Shared	50	16.6667	No	No	No	No	5	4
275	8x47	8x50	Shared	50	66.6667	No	No	Yes	Yes	8	9
276	1x50	2x47	Shared	50	33.3333	No	Yes	No	No	9	9
277	2x49	4x50	Shared	0	0	No	No	Yes	Yes	8	9
278	2x37	2x39	Shared	25	25	No	No	No	No	7	8
279	1x60	I1x49	Shared	50	50	Yes	Yes	No	No	6	6
280	3x47	5x57	Shared	50	33.3333	No	No	No	No	9	6
281	2x41	4x42	Shared	50	66.6667	No	No	No	Yes	4	7
282	3x54	5x61	Shared	50	100	Yes	No	No	No	9	9
283	5x51	5x55	Shared	50	50	No	Yes	No	No	6	5
284	1x58	2x44	Shared	25	50	No	No	Yes	No	3	5
285	6x32	6x36	Shared	0.961538	20.8333	No	No	No	No	7	8
286	3x27	4x61	Shared	50	50	No	No	No	No	4	5
287	4x58	4x59	Shared	50	16.6667	No	No	No	No	4	6
288	7x26	7x30	Shared	50	16.6667	No	No	No	No	0	4
289	1x60	8x53	Shared	50	50	Yes	Yes	No	No	6	6
290	6x49	6x50	Shared	0	50	No	No	No	No	7	9
291	3x34	4x57	Shared	0.961538	100	Yes	Yes	No	No	5	6
292	2x52	3x35	Shared	50	100	No	No	No	Yes	6	7
293	5x58	6x42	Shared	50	50	Yes	Yes	No	No	9	5
294	6x39	6x43	Shared	25	50	No	No	No	No	6	6
295	1x54	2x44	Shared	1.92308	33.3333	No	No	Yes	No	7	5
296	7x51	7x55	Shared	0.961538	33.3333	No	No	No	No	7	6
297	1x42	7x43	Shared	12.5	54.1667	No	No	No	No	7	5
298	3x44	5x53	Shared	0	33.3333	No	No	No	No	7	6
299	6x31	6x35	Shared	37.5	16.6667	No	No	No	No	5	7
300	3x54	5x64	Shared	12.5	50	Yes	No	No	No	9	5
301	6x461	6x47	Shared	0	0	No	No	No	No	0	8
302	1x48	1x49	Shared	0	0	No	No	No	No	4	8
303	1x44	1x48	Shared	0.961538	0	No	No	No	No	5	4
304	I2x53	I2x54	Shared	25	50	Yes	Yes	No	No	7	4
305	I1x48	I1x51	Shared	17.3077	50	No	No	No	No	6	7
306	6x24	6x28	Shared	25	4.16667	Yes	No	No	No	2	3
307	7x54	8x54	Shared	0	50	No	No	No	Yes	7	7
308	8x60	8x61	Shared	18.2692	50	No	No	No	No	6	6
309	1x41	1x45	Shared	0	20.8333	No	No	No	No	5	4
310	1x37	1x40	Shared	12.5	0	No	No	No	No	5	4
311	4x48	4x51	Shared	12.5	16.6667	No	No	No	No	1	4
312	5x48	5x52	Shared	9.61539	66.6667	No	No	No	No	5	3
313	5x72	I3	Shared	1.92308	0	No	No	No	No	0	4
314	5x68	5x71	Shared	0	37.5	No	No	No	No	7	0
315	5x66	5x70	Shared	0	66.6667	No	Yes	No	No	5	0
316	1x31	7x32	nucleotide_on	0	100	No	No	No	No	4	1
317	1x32	2x64	nucleotide_on	0	100	No	Yes	No	No	4	3
318	1x35	7x38	nucleotide_on	0	100	Yes	Yes	Yes	No	5	5
319	1x36	2x61	nucleotide_on	0	100	No	No	No	No	5	6
320	1x57	8x50	nucleotide_on	0	100	No	Yes	Yes	Yes	8	9
321	2x42	3x49	nucleotide_on	0	100	Yes	Yes	Yes	Yes	8	9
322	2x46	2x50	nucleotide_on	0	100	No	Yes	Yes	Yes	9	9
323	2x46	3x42	nucleotide_on	0	100	No	Yes	No	Yes	9	8
324	2x46	3x43	nucleotide_on	0	100	No	Yes	No	No	9	8
325	2x46	7x49	nucleotide_on	0	100	No	Yes	Yes	Yes	9	9
326	2x50	3x39	nucleotide_on	0	100	Yes	Yes	No	No	9	9
327	2x56	3x32	nucleotide_on	0	100	No	No	No	No	6	6
328	2x57	2x58	nucleotide_on	0	100	Yes	No	No	No	6	8
329	3x33	Lig	nucleotide_on	0	100	No	No	Yes	Yes	4	0
330	3x36	Lig	nucleotide_on	0	100	No	No	Yes	Yes	6	0
331	3x37	5x43	nucleotide_on	0	100	Yes	No	No	No	6	5
332	3x43	7x49	nucleotide_on	0	100	No	No	Yes	Yes	8	9
333	3x43	7x53	nucleotide_on	0	100	No	No	Yes	No	8	9
334	3x44	5x50	nucleotide_on	0	100	No	No	No	No	7	8
335	3x46	3x50	nucleotide_on	0	100	No	No	Yes	No	9	9
336	3x46	7x53	nucleotide_on	0	100	No	No	Yes	No	9	9
337	3x49	3x53	nucleotide_on	0	100	Yes	Yes	No	No	9	8
338	3x50	7x53	nucleotide_on	0	100	Yes	No	Yes	No	9	9
339	5x40	Lig	nucleotide_on	0	100	No	Yes	Yes	Yes	5	0
340	5x58	6x40	nucleotide_on	0	100	Yes	Yes	No	No	9	8
341	6x43	7x48	nucleotide_on	0	100	No	No	No	No	6	6
342	6x51	7x37	nucleotide_on	0	100	No	Yes	No	No	6	5
343	6x51	7x41	nucleotide_on	0	100	No	Yes	No	No	6	7
344	E3	E3	nucleotide_on	0	100	No	Yes	No	Yes	3	3
345	7x30	7x33	nucleotide_on	0	100	No	No	No	No	4	4
346	7x54	8x50	nucleotide_on	0	100	No	No	Yes	Yes	7	9
347	7x55	8x51	nucleotide_on	0	100	No	No	No	No	6	8
348	1x32	7x31	nucleotide_on	0	100	No	Yes	Yes	No	4	3
349	2x41	4x39	nucleotide_on	0	100	No	No	No	No	4	3
350	5x59	5x63	nucleotide_on	0	100	No	No	No	No	3	4
351	3x37	Lig	nucleotide_on	0	100	Yes	No	Yes	Yes	6	0
352	1x57	2x43	nucleotide_on	0	100	No	Yes	No	No	8	8
353	2x53	3x32	nucleotide_on	0	100	No	No	No	No	8	6
354	4x64	E2	nucleotide_on	0	100	No	No	Yes	Yes	0	3
355	5x36	5x40	nucleotide_on	0	100	No	No	No	Yes	5	5
356	5x40	6x59	nucleotide_on	0	100	No	Yes	No	Yes	5	4
357	6x58	6x62	nucleotide_on	0	100	No	No	No	No	4	0
358	4x60	Lig	nucleotide_on	0	100	No	No	Yes	Yes	4	0
359	5x69	I3	nucleotide_on	0	100	No	Yes	No	No	4	4
360	1x50	2x51	nucleotide_on	0	66.6667	No	Yes	Yes	No	9	7
361	6x51	6x52	nucleotide_on	0	54.1667	No	Yes	No	No	6	7
362	5x36	5x38	nucleotide_on	0	50	No	No	No	No	5	3
363	5x51	6x49	nucleotide_on	0	66.6667	No	Yes	No	No	6	7
364	1x53	8x50	nucleotide_on	0	50	No	No	Yes	Yes	9	9
365	5x51	6x44	nucleotide_on	0	50	No	Yes	No	No	6	9
366	2x60	3x32	nucleotide_on	0	50	No	No	No	No	7	6
367	7x28	7x32	nucleotide_on	0	50	No	No	No	No	0	1
368	2x66	E1	nucleotide_on	0	50	No	No	Yes	Yes	3	0
369	6x61	7x27	nucleotide_on	0	50	No	No	No	No	4	0
370	1x28	7x31	nucleotide_on	0	50	No	No	Yes	No	0	3
371	3x26	4x61	nucleotide_on	0	66.6667	No	No	No	No	5	5
372	6x58	E3	nucleotide_on	0	50	No	No	No	Yes	4	3
373	8x48	8x51	nucleotide_on	0	66.6667	No	No	No	No	4	8
374	3x50	5x58	nucleotide_on	0	66.6667	Yes	No	Yes	Yes	9	9
375	7x30	E3	nucleotide_on	0	66.6667	No	No	No	Yes	4	3
376	1x43	1x47	nucleotide_on	0	50	No	Yes	No	No	5	6
377	1x56	8x54	nucleotide_on	0	66.6667	No	No	No	Yes	8	7
378	5x62	6x30	nucleotide_on	0	50	No	No	No	No	6	6
379	5x69	6x30	nucleotide_on	0	20.8333	No	Yes	No	No	4	6
380	2x551	3x35	nucleotide_on	0	50	No	No	No	Yes	5	7
381	1x29	1x32	nucleotide_on	0	50	No	No	No	Yes	6	4
382	2x40	8x50	nucleotide_on	0	50	No	Yes	Yes	Yes	8	9
383	8x48	8x52	nucleotide_on	0	50	No	No	No	No	4	4
384	5x41	6x59	nucleotide_on	0	50	No	No	No	Yes	4	4
385	3x31	3x35	nucleotide_on	0	50	No	No	No	Yes	4	7
386	5x33	E2	nucleotide_on	0	50	No	No	Yes	Yes	0	3
387	4x52	4x56	nucleotide_on	0	50	No	No	No	No	4	5
388	2x38	4x42	nucleotide_on	0	33.3333	No	No	No	Yes	6	7
389	1x42	7x42	nucleotide_on	0	50	No	No	No	No	7	7
390	3x20	E1	nucleotide_on	0	50	No	No	Yes	Yes	0	0
391	1x43	2x54	nucleotide_on	0	33.3333	No	Yes	No	No	5	7
392	3x34	3x35	nucleotide_on	0	54.1667	Yes	Yes	No	Yes	5	7
393	8x49	I1x50	nucleotide_on	0	50	No	No	No	No	6	8
394	1x46	7x46	nucleotide_on	0	50	No	No	No	No	8	9
395	3x55	5x64	nucleotide_on	0	33.3333	No	No	No	No	7	5
396	5x56	5x60	nucleotide_on	0	54.1667	No	No	No	No	4	4
397	E1	E2	nucleotide_on	0	50	Yes	Yes	Yes	Yes	0	3
398	5x66	6x30	nucleotide_on	0	50	No	Yes	No	No	5	6
399	5x66	5x67	nucleotide_on	0	33.3333	No	Yes	No	No	5	4
400	4x40	4x43	nucleotide_on	0	41.6667	No	No	No	No	5	1
401	2x55	2x551	nucleotide_on	0	50	No	No	No	No	4	5
402	3x52	3x56	nucleotide_on	0	50	No	No	No	Yes	5	6
403	4x59	5x35	nucleotide_on	0	50	No	No	No	No	6	0
404	5x51	6x46	nucleotide_on	0	50	No	Yes	No	No	6	6
405	5x34	5x38	nucleotide_on	0	50	No	No	No	No	0	3
406	6x63	E2	nucleotide_on	0	50	No	No	Yes	Yes	0	3
407	2x41	4x43	nucleotide_on	0	33.3333	No	No	No	No	4	1
408	5x64	5x67	nucleotide_on	0	16.6667	No	No	No	No	5	4
409	4x41	I2x56	nucleotide_on	0	25	No	No	No	No	5	4
410	6x25	6x26	nucleotide_on	0	50	No	No	No	No	3	3
411	2x59	3x23	nucleotide_on	0	50	No	No	No	No	5	1
412	7x26	7x29	nucleotide_on	0	50	No	No	No	No	0	0
413	5x69	6x29	nucleotide_on	0	50	No	Yes	No	No	4	6
414	5x65	6x34	nucleotide_on	0	50	No	No	No	No	8	7
415	1x59	1x60	nucleotide_on	0	25	No	No	Yes	Yes	5	6
416	3x22	3x23	nucleotide_on	0	50	No	No	No	No	3	1
417	5x66	6x35	nucleotide_on	0	50	No	Yes	No	No	5	7
418	4x42	I2x56	nucleotide_on	0	50	No	Yes	No	No	7	4
419	7x23	7x25	nucleotide_on	0	33.3333	No	No	No	No	0	0
420	5x62	6x39	nucleotide_on	0	16.6667	No	No	No	No	6	6
421	3x48	5x57	nucleotide_on	0	16.6667	No	No	No	No	6	6
422	6x57	E3	nucleotide_on	0	8.33333	No	No	No	Yes	4	3
423	6x56	6x60	nucleotide_on	0	16.6667	No	No	No	No	5	4
424	8x54	8x58	nucleotide_on	0	16.6667	No	Yes	No	No	7	5
425	6x50	7x40	nucleotide_on	0	25	No	No	No	No	9	7
426	6x37	7x56	nucleotide_on	0	33.3333	No	No	No	No	8	7
427	3x34	4x58	nucleotide_on	0	16.6667	Yes	Yes	No	No	5	4
428	7x36	7x39	nucleotide_on	0	16.6667	No	No	No	No	3	5
429	1x34	1x38	nucleotide_on	0	33.3333	No	No	No	No	4	5
430	2x65	E1x50	nucleotide_on	0	16.6667	No	No	No	No	4	3
431	5x73	6x26	nucleotide_on	0	16.6667	No	No	No	No	0	3
432	3x56	I2x50	nucleotide_on	0	0	No	Yes	No	No	6	8
433	8x52	8x55	nucleotide_on	0	16.6667	No	No	No	No	4	5
434	2x48	4x50	nucleotide_on	0	8.33333	No	No	Yes	Yes	6	9
435	4x38	I2x55	nucleotide_on	0	16.6667	No	No	No	No	8	5
436	5x65	6x33	nucleotide_on	0	16.6667	No	No	No	No	8	7
437	1x30	1x34	nucleotide_on	0	16.6667	No	No	No	No	5	4
438	6x49	6x53	nucleotide_on	0	16.6667	No	No	No	No	7	6
439	7x23	7x26	nucleotide_on	0	16.6667	No	No	No	No	0	0
440	4x40	4x44	nucleotide_on	0	0	No	No	No	No	5	3
441	4x58	4x62	nucleotide_on	0	8.33333	No	No	No	No	4	4
442	I2x51	I2x54	nucleotide_on	0	16.6667	No	No	No	No	6	4
443	6x27	6x31	nucleotide_on	0	16.6667	No	No	No	No	1	5
444	1x56	8x57	nucleotide_on	0	0	No	No	No	No	8	7
445	4x63	5x32	nucleotide_on	0	16.6667	Yes	No	No	No	5	0
446	5x68	I3	nucleotide_on	0	0	No	No	No	No	7	4
447	1x32	2x67	nucleotide_on	0	16.6667	No	Yes	No	No	4	0
448	3x19	E1	nucleotide_on	0	16.6667	No	No	Yes	Yes	0	0
449	3x18	3x19	nucleotide_on	0	16.6667	No	No	No	No	0	0
450	5x31	5x34	nucleotide_on	0	16.6667	No	No	No	No	0	0
451	6x25	6x28	nucleotide_on	0	16.6667	No	No	No	No	3	3
452	8x52	8x56	nucleotide_on	0	4.16667	No	No	No	No	4	5
453	8x58	8x59	nucleotide_on	0	0	No	No	No	No	5	4
454	8x57	8x61	nucleotide_on	0	8.33333	No	No	No	No	7	6
455	5x69	5x73	nucleotide_on	0	16.6667	No	Yes	No	No	4	0
456	1x58	I1x51	nucleotide_on	0	8.33333	No	No	No	No	3	7
457	7x57	7x59	nucleotide_on	0	16.6667	No	No	No	No	0	0
458	4x55	4x56	nucleotide_on	0	0	No	No	No	No	4	5
459	7x57	8x50	nucleotide_on	0	16.6667	No	No	Yes	Yes	0	9
460	4x46	4x47	nucleotide_on	0	0	No	No	No	No	8	4
461	4x44	4x48	nucleotide_on	0	0	No	No	No	No	3	1
462	6x33	7x58	nucleotide_on	0	0	No	No	No	No	7	0
463	1x61	2x40	nucleotide_on	0	0	No	No	No	Yes	0	8
464	5x30	E2	nucleotide_on	0	0	No	No	Yes	Yes	0	3

Orange: nodes, hubs and links specific of nucleotide_off network

Green: nodes, hubs and links shared by both networks

Purple: nodes, hubs and links specific of nucleotide_on network

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Owner: the name of the network the hub belong to or "Shared" if the corresponding hub is present in both networks.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub in the corresponding network.

Num Of Links: the number of links of the corresponding hub in the corresponding network.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Owner	nucleotide_off Avg Int. Strength	nucleotide_on Avg Int. Strength	nucleotide_off Num Of Links	nucleotide_on Num Of Links	ConSurf
1	1x55	nucleotide_off	0	0	4	1	4
2	2x44	nucleotide_off	0	0	5	3	5
3	2x51	nucleotide_off	0	0	4	1	7
4	2x57	nucleotide_off	47.1154	33.3333	4	3	6
5	2x63	nucleotide_off	0	16.6667	4	1	3
6	3x37	nucleotide_off	100	29.1667	5	3	6
7	3x50	nucleotide_off	39.4231	0	4	3	9
8	3x51	nucleotide_off	50	0	4	3	7
9	3x54	nucleotide_off	0	0	4	2	9
10	4x63	nucleotide_off	50	0	4	2	5
11	E2x50	nucleotide_off	0	0	4	2	9
12	E2x52	nucleotide_off	0	0	4	3	4
13	5x461	nucleotide_off	25	33.3333	4	3	8
14	6x24	nucleotide_off	0	0	4	1	2
15	6x54	nucleotide_off	0	0	4	1	4
16	7x31	nucleotide_off	50	0	4	3	3
17	7x34	nucleotide_off	0	33.3333	4	3	4
18	7x35	nucleotide_off	0	50	4	2	3
19	7x38	nucleotide_off	0	33.3333	4	3	5
20	7x45	nucleotide_off	12.5	0	5	3	9
21	7x53	nucleotide_off	87.5	79.1667	4	3	9
22	NT	nucleotide_off	50	16.6667	6	3	0
23	I1	nucleotide_off	50	0	5	1	0
24	1x35	Shared	12.5	45.8333	4	4	5
25	1x39	Shared	74.0385	70.8333	6	5	6
26	1x60	Shared	25	0	4	4	6
27	2x42	Shared	50	0	5	5	8
28	2x50	Shared	50	50	4	5	9
29	3x34	Shared	0	0	4	4	5
30	3x49	Shared	20.1923	0	4	4	9
31	I2x53	Shared	22.1154	50	4	4	7
32	4x50	Shared	0	16.6667	4	5	9
33	E2	Shared	100	100	16	18	3
34	5x39	Shared	100	41.6667	5	4	6
35	5x58	Shared	50	58.3333	6	8	9
36	6x48	Shared	81.7308	50	6	5	8
37	7x49	Shared	12.5	37.5	4	4	9
38	8x50	Shared	37.5	29.1667	4	7	9
39	Lig	Shared	100	100	10	12	0
40	E1	Shared	50	33.3333	4	4	0
41	1x32	nucleotide_on	0	0	1	4	4
42	1x43	nucleotide_on	0	0	2	4	5
43	1x50	nucleotide_on	0	0	3	4	9
44	1x57	nucleotide_on	50	16.6667	3	4	8
45	2x40	nucleotide_on	0	33.3333	3	4	8
46	2x46	nucleotide_on	0	20.8333	2	4	9
47	3x35	nucleotide_on	0	16.6667	2	4	7
48	3x42	nucleotide_on	50	50	3	4	8
49	3x56	nucleotide_on	0	0	2	4	6
50	4x42	nucleotide_on	0	0	2	4	7
51	5x40	nucleotide_on	40.3846	29.1667	1	4	5
52	5x51	nucleotide_on	0	16.6667	2	4	6
53	5x66	nucleotide_on	0	0	2	4	5
54	5x69	nucleotide_on	0	0	2	4	4
55	6x51	nucleotide_on	0	16.6667	1	4	6
56	6x59	nucleotide_on	36.5385	8.33333	3	4	4
57	E3	nucleotide_on	69.2308	45.8333	3	7	3
58	8x54	nucleotide_on	0	0	3	4	7

Orange: nodes, hubs and links specific of nucleotide_off network

Green: nodes, hubs and links shared by both networks

Purple: nodes, hubs and links specific of nucleotide_on network

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Owner: the name of the network the link belong to or "Shared" if the corresponding link is present in both networks.

Recurrence: the relative Recurrence in the filtered pool of shortest paths.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Owner	nucleotide_off Recurrence	nucleotide_on Recurrence	nucleotide_off Hub1?	nucleotide_on Hub1?	nucleotide_off Hub2?	nucleotide_on Hub2?	ConSurf1	ConSurf2
1	1x39	2x57	nucleotide_off	29.3117	7.60878	Yes	Yes	Yes	No	6	6
2	1x35	7x35	nucleotide_off	60.4012	3.37129	Yes	Yes	Yes	No	5	3
3	7x31	7x35	nucleotide_off	21.7439	2.12281	Yes	No	Yes	No	3	3
4	7x31	Lig	nucleotide_off	21.9502	0	Yes	No	Yes	Yes	3	0
5	5x39	5x42	nucleotide_off	99.8552	2.35868	Yes	Yes	No	No	6	5
6	5x42	5x461	nucleotide_off	100	0	No	No	Yes	No	5	8
7	3x37	5x461	nucleotide_off	99.7031	6.39284	Yes	No	Yes	No	6	8
8	3x37	4x53	nucleotide_off	95.8431	0	Yes	No	No	No	6	8
9	3x38	4x53	nucleotide_off	93.3809	1.35014	No	No	No	No	7	8
10	3x38	4x50	nucleotide_off	93.0405	2.69622	No	No	Yes	Yes	7	9
11	2x45	4x50	nucleotide_off	85.0708	0.0569337	No	No	Yes	Yes	9	9
12	2x45	4x46	nucleotide_off	88.3912	2.69622	No	No	No	No	9	8
13	2x42	4x46	nucleotide_off	87.9567	0	Yes	Yes	No	No	8	8
14	3x46	6x37	nucleotide_off	84.4444	0	No	No	No	No	9	8
15	5x58	6x37	nucleotide_off	83.9954	4.9939	Yes	Yes	No	No	9	8
16	3x51	5x61	nucleotide_off	72.3974	0	Yes	No	No	No	7	9
17	3x54	5x61	nucleotide_off	68.4108	1.40708	Yes	No	No	No	9	9
18	3x54	6x30	nucleotide_off	58.2648	0	Yes	No	No	No	9	6
19	3x50	6x30	nucleotide_off	56.2914	0	Yes	No	No	No	9	6
20	2x39	3x50	nucleotide_off	44.1829	0	No	No	Yes	No	8	9
21	1x57	2x40	nucleotide_off	23.2502	0	No	Yes	No	Yes	8	8
22	1x57	2x44	nucleotide_off	15.7874	6.01464	No	Yes	Yes	No	8	5
23	7x35	7x38	nucleotide_off	41.0689	0	Yes	No	Yes	No	3	5
24	7x38	E2x52	nucleotide_off	20.1543	0	Yes	No	Yes	No	5	4
25	E2	E2x52	nucleotide_off	21.5012	0.235868	Yes	Yes	Yes	No	3	4
26	3x36	3x37	nucleotide_off	50.7296	0	No	No	Yes	No	6	6
27	3x36	6x48	nucleotide_off	49.8171	0	No	No	Yes	Yes	6	8
28	2x40	I1x50	nucleotide_off	15.0234	7.49085	No	Yes	No	No	8	8
29	8x50	I1x50	nucleotide_off	10.3849	0	Yes	Yes	No	No	9	8
30	3x54	5x65	nucleotide_off	12.916	0	Yes	No	No	No	9	8
31	5x65	6x31	nucleotide_off	11.75	5.12403	No	No	No	No	8	5
32	6x40	7x49	nucleotide_off	11.0113	0	No	No	Yes	Yes	8	9
33	1x42	2x57	nucleotide_off	18.7529	0	No	No	Yes	No	7	6
34	1x42	7x47	nucleotide_off	10.7579	3.83896	No	No	No	No	7	6
35	Lig	NT	nucleotide_off	11.0403	0	Yes	Yes	Yes	No	0	0
36	1x35	1x39	Shared	50.0815	27.5885	Yes	Yes	Yes	Yes	5	6
37	E2	Lig	Shared	66.4156	46.6775	Yes	Yes	Yes	Yes	3	0
38	5x39	E2	Shared	98.4973	14.2619	Yes	Yes	Yes	Yes	6	3
39	2x42	3x46	Shared	84.7449	62.2163	Yes	Yes	No	No	8	9
40	3x47	5x58	Shared	77.713	45.5876	No	No	Yes	Yes	9	9
41	3x47	5x57	Shared	78.5169	44.6767	No	No	No	No	9	6
42	3x51	5x57	Shared	77.9375	42.4888	Yes	No	No	No	7	6
43	2x37	2x39	Shared	39.0738	40.3416	No	No	No	No	7	8
44	2x37	2x40	Shared	37.39	39.2355	No	No	No	Yes	7	8
45	7x38	Lig	Shared	21.3347	34.6401	Yes	No	Yes	Yes	5	0
46	6x48	7x45	Shared	38.049	98.8288	Yes	Yes	Yes	No	8	9
47	7x45	7x49	Shared	34.5331	98.4465	Yes	No	Yes	Yes	9	9
48	2x50	7x49	Shared	18.5465	18.2676	Yes	Yes	Yes	Yes	9	9
49	6x58	E3	nucleotide_on	0	26.5555	No	No	No	Yes	4	3
50	6x58	7x34	nucleotide_on	0.119492	15.2745	No	No	Yes	No	4	4
51	1x35	7x38	nucleotide_on	0	35.9536	Yes	Yes	Yes	No	5	5
52	6x58	6x62	nucleotide_on	0	12.802	No	No	No	No	4	0
53	6x62	Lig	nucleotide_on	3.4037	13.599	No	No	Yes	Yes	0	0
54	6x51	Lig	nucleotide_on	1.03559	99.5039	No	Yes	Yes	Yes	6	0
55	6x51	7x41	nucleotide_on	0	100	No	Yes	No	No	6	7
56	6x48	7x41	nucleotide_on	1.24923	99.9878	Yes	Yes	No	No	8	7
57	1x50	2x50	nucleotide_on	7.40486	12.6922	No	Yes	Yes	Yes	9	9
58	7x34	Lig	nucleotide_on	6.32944	14.1114	Yes	No	Yes	Yes	4	0
59	3x43	7x49	nucleotide_on	0	84.9614	No	No	Yes	Yes	8	9
60	3x43	7x53	nucleotide_on	0	97.3404	No	No	Yes	No	8	9
61	3x46	7x53	nucleotide_on	0	51.7771	No	No	Yes	No	9	9
62	2x42	3x49	nucleotide_on	0	47.3811	Yes	Yes	Yes	Yes	8	9
63	2x39	3x49	nucleotide_on	6.34754	41.4274	No	No	Yes	Yes	8	9
64	2x40	8x50	nucleotide_on	0	31.0573	No	Yes	Yes	Yes	8	9
65	2x46	3x42	nucleotide_on	0	14.4449	No	Yes	No	Yes	9	8
66	2x50	7x46	nucleotide_on	9.50501	10.2481	Yes	Yes	No	No	9	9
67	3x26	E2	nucleotide_on	0.923344	10.2399	No	No	Yes	Yes	5	3
68	4x59	5x39	nucleotide_on	2.49484	23.2452	No	No	Yes	Yes	6	6
69	4x58	4x59	nucleotide_on	1.24923	20.0041	No	No	No	No	4	6
70	3x34	4x58	nucleotide_on	0	15.4575	Yes	Yes	No	No	5	4
71	4x60	Lig	nucleotide_on	0	13.4933	No	No	Yes	Yes	4	0
72	4x60	5x39	nucleotide_on	3.59199	12.8426	No	No	Yes	Yes	4	6
73	3x50	7x53	nucleotide_on	0	44.9248	Yes	No	Yes	No	9	9
74	3x50	5x58	nucleotide_on	0	55.5226	Yes	No	Yes	Yes	9	9
75	3x51	3x55	nucleotide_on	6.18822	36.8768	Yes	No	No	No	7	7
76	3x55	5x64	nucleotide_on	0	30.9963	No	No	No	No	7	5
77	2x42	4x42	nucleotide_on	4.15324	16.771	Yes	Yes	No	Yes	8	7
78	5x40	Lig	nucleotide_on	0	10.7117	No	Yes	Yes	Yes	5	0
79	5x64	5x67	nucleotide_on	0	27.7715	No	No	No	No	5	4
80	5x66	5x67	nucleotide_on	0	26.5596	No	Yes	No	No	5	4
81	5x66	6x30	nucleotide_on	0	16.7629	No	Yes	No	No	5	6
82	6x44	6x48	nucleotide_on	2.24137	10.6019	No	No	Yes	Yes	9	8
83	7x30	E3	nucleotide_on	0	10.8865	No	No	No	Yes	4	3
84	5x69	6x30	nucleotide_on	0	10.9679	No	Yes	No	No	4	6
85	2x46	3x43	nucleotide_on	0	12.863	No	Yes	No	No	9	8
86	3x46	3x50	nucleotide_on	0	11.3095	No	No	Yes	No	9	9

Here, those paths that begin and end at given residue pair(s) or that pass through a residue are used to generate a novel metapath. Such a path filtering is particularly recommended if some information on allosteric residues is available. The selection syntax for a residue pair ("Pairs") is C:C:c534,A:A:?600 (the lower-case "c" stands for cytosine and "?" indicates any non standard amino acid or nucleotide residue). Selection of more than one apical residue pair has the following syntax: C:C:c534,A:A:?600,C:C:c534,A:A:E41. Only one residue can be selected as a tail ("Tail"). For midway residue(s), each residue must be separated by a comma as well e.g. A:A:?600,A:A:E41.

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Node1	Node2	Owner	Net1LinkStrength	Net2LinkStrength	Comm1	Comm2	Node1Shell	Node2Shell
1x35	7x35	Shared	6.1201	11.99	0	0	2	2
E1x51	E2	nucleotide_off	4.52365	0	1	0	2	1
3x22	3x26	nucleotide_off	7.27096	0	1	1	2	2
3x22	E2	Shared	16.1365	15.7342	1	1	2	1
3x23	E2	nucleotide_off	4.385	0	0	0	2	1
3x25	E2	Shared	6.46558	2.96333	1	1	2	1
3x26	E2	Shared	8.86288	4.91958	1	1	2	1
3x29	E2x52	Shared	10.0005	3.59708	0	0	2	1
3x32	3x33	nucleotide_off	5.39894	0	0	0	2	1
3x33	4x60	nucleotide_off	4.59	0	0	0	1	1
3x36	6x48	nucleotide_off	4.94587	0	0	0	1	2
3x37	4x56	nucleotide_off	4.10577	0	7	0	1	2
3x37	5x461	Shared	8.2899	4.19667	7	0	1	2
4x56	5x461	Shared	6.93683	5.40667	7	0	2	2
4x60	5x39	Shared	9.85615	8.19042	0	0	1	2
4x63	E2	Shared	6.1325	2.0725	1	1	2	1
5x36	E2	Shared	15.351	9.08	1	1	2	1
5x39	E2	Shared	6.95538	5.095	1	1	2	1
E2	E2	Shared	65.8613	54.7033	1	1	1	1
E2	E2x51	Shared	13.143	10.5054	1	1	1	2
E2	E2x52	Shared	6.30212	8.78333	1	1	1	1
E2x52	Lig	Shared	20.8043	18.6508	1	1	1	0
E2	Lig	Shared	12.8483	8.52583	1	1	1	0
5x37	6x59	nucleotide_off	4.37096	0	0	0	2	2
5x39	5x43	nucleotide_off	5.58058	0	1	1	2	2
5x40	6x55	Shared	6.63971	4.82417	0	1	1	1
6x48	7x41	Shared	5.38721	3.27667	6	0	2	2
6x51	Lig	Shared	8.31135	3.69875	0	0	1	0
6x54	7x37	Shared	5.315	2.03917	0	0	2	2
6x55	Lig	Shared	6.40288	5.13375	0	1	1	0
6x58	Lig	nucleotide_off	8.09808	0	1	1	1	0
7x31	7x35	Shared	8.89923	6.86667	1	0	1	2
7x34	7x38	Shared	6.89933	4.34333	1	1	1	1
7x34	Lig	Shared	4.37548	5.31792	1	1	1	0
7x38	Lig	Shared	6.65212	7.71083	1	1	1	0
1x31	7x35	nucleotide_off	9.49019	0	1	0	2	2
7x31	Lig	nucleotide_off	6.22683	0	1	0	1	0
7x35	7x38	nucleotide_off	4.88442	0	1	0	2	1
E3	NT	Shared	10.995	2.81167	0	1	2	1
7x24	NT	Shared	5.035	2.12333	0	0	2	1
Lig	NT	nucleotide_off	13.085	0	1	1	0	1
7x28	NT	Shared	5.015	4	0	0	2	1
7x31	NT	nucleotide_off	10.575	0	1	0	1	1
E1	NT	nucleotide_off	4.505	0	0	1	2	1
1x31	7x31	nucleotide_off	5.075	0	1	0	2	1
1x32	E1	nucleotide_off	8.8	0	0	0	2	2
E1x49	E2	Shared	6.46	3.44833	1	0	2	1
3x36	3x37	nucleotide_off	7.035	0	0	0	1	1
3x37	6x52	nucleotide_off	3.81	0	7	0	1	2
4x63	5x36	nucleotide_off	8.44	0	1	1	2	2
7x38	E2x52	nucleotide_off	4.765	0	1	1	1	1
5x33	6x62	nucleotide_off	7.29	0	0	0	2	1
6x58	7x34	Shared	8.72	11.215	1	1	1	1
6x62	Lig	Shared	12.145	4.24	0	0	1	0
3x37	4x53	nucleotide_off	3.31087	0	7	0	1	2
5x37	6x55	Shared	3.23606	2.68792	0	0	2	1
3x21	E2	Shared	3.015	2.10417	0	0	2	1
5x38	E2	nucleotide_off	2.65202	0	0	0	2	1
3x29	4x64	nucleotide_off	2.635	0	0	0	2	2
6x54	7x34	nucleotide_off	2.36279	0	0	0	2	1
5x33	6x63	nucleotide_off	2.075	0	0	0	2	2
1x35	7x38	nucleotide_on	0	4.25708	0	0	2	1
3x33	Lig	nucleotide_on	0	8.42333	0	0	1	0
3x36	Lig	nucleotide_on	0	5.36667	0	0	1	0
3x37	5x43	nucleotide_on	0	3.7725	7	0	1	2
5x40	Lig	nucleotide_on	0	3.92208	0	1	1	0
6x51	7x37	nucleotide_on	0	3.4125	0	0	1	2
6x51	7x41	nucleotide_on	0	5.04208	0	0	1	2
E3	E3	nucleotide_on	0	3.80375	0	1	2	2
1x32	7x31	nucleotide_on	0	3.30875	0	0	2	1
3x37	Lig	nucleotide_on	0	3.46042	7	0	1	0
4x64	E2	nucleotide_on	0	5.965	0	0	2	1
5x36	5x40	nucleotide_on	0	3.4	1	1	2	1
5x40	6x59	nucleotide_on	0	3.69667	0	1	1	2
6x58	6x62	nucleotide_on	0	5.265	1	1	1	1
4x60	Lig	nucleotide_on	0	4.04833	0	0	1	0
6x51	6x52	nucleotide_on	0	3.16083	0	0	1	2
5x36	5x38	nucleotide_on	0	3.0825	1	1	2	2
1x28	7x31	nucleotide_on	0	2.75	0	0	2	1
6x58	E3	nucleotide_on	0	2.70208	1	1	1	2
5x33	E2	nucleotide_on	0	2.36333	0	0	2	1
E1	E2	nucleotide_on	0	2.11833	0	1	2	1
6x63	E2	nucleotide_on	0	1.87	0	0	2	1
3x22	3x23	nucleotide_on	0	1.71875	1	1	2	2
5x30	E2	nucleotide_on	0	0.24	0	0	2	1

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Difference Members
	Id	Description
	nucleotide_off	adenosine_off p2y_off
	nucleotide_on	adenosine_on p2y_on

Network Difference
Value	nucleotide_off	nucleotide_on
I_min	3.76933	3.24583
Number of Linked Nodes	292	297
Number of Specific Nodes	8 (2.74%)	13 (4.38%)
Number of Shared Nodes	284 (97.26%)	284 (95.62%)
Number of Links	315	313
Number of Specific Links	151 (47.94%)	149 (47.60%)
Number of Shared Links	164 (52.06%)	164 (52.40%)
Number of Hubs	40	35
Number of Specific Hubs	23 (57.50%)	18 (51.43%)
Number of Shared Hubs	17 (42.50%)	17 (48.57%)
Average % Shared Neighbours (Jaccard)	38.51
Average % Shared Neighbours (Otsuka)	47.25
Average % Shared Neighbours (Overlap Coefficient)	56.12
Average % Shared Cliques (k3-6)	79.55
Graphlets Similarity	0.471559

Paths Difference
Value	nucleotide_off	nucleotide_on
Number Of Nodes in MetaPath	47	49
Specific Nodes in MetaPath	25 (53.19%)	27 (55.10%)
Shared Nodes in MetaPath	284 (97.26%)	284 (97.26%)
Number Of Links MetaPath	48	51
Specific Links in MetaPath	35 (72.92%)	38 (74.51%)
Shared Links in MetaPath	164 (52.06%)	164 (52.06%)
Number of Shortest Paths	50535	48334
Length Of Smallest Path	3	3
Average Path Length	18.6618	14.2254
Length of Longest Path	42	32
Minimum Path Strength	0.426875	0.4225
Average Path Strength	5.51434	4.66426
Maximum Path Strength	16.6579	13.0077
Minimum Path Correlation	0.700673	0.704167
Average Path Correlation	0.914217	0.908486
Maximum Path Correlation	0.99	0.986667
Minimum % Of Corr. Nodes	2.63158	3.44828
Average % Of Corr. Nodes	36.6939	37.9251
Maximum % Of Corr. Nodes	100	100
Minimum Path Hubs %	0	0
Average Path Hubs %	46.2158	39.9531
Maximum Path Hubs %	100	100

Details about the values in these tables can be found in the corresponding documentation page .

You can download a compressed (zip) file with structure(s), 3D outputs (as PyMol and VMD scripts) and numerical data files (as csv and plain text files).

Download nucleotide_off_on.zip<

You can click to copy the link of this page to easily come back here later

or use this QR code to link and share this page.

You can also read or download a guide explaining the meaning of all files and numerical data.