psnGPCR

Press and hold down the left mouse button and move the mouse to rotate.
Press and hold down the central mouse button and move the mouse to translate.
Use the mouse wheel to zoom in or out.
Click on any atom on your molecule and the corresponding residue label will be placed beneath the viewer.

Orange: nodes, hubs and links specific of ox1_off_allo network

Green: nodes, hubs and links shared by both networks

Purple: nodes, hubs and links specific of ox1_off network

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Owner: the name of the network the link belong to or "Shared" if the corresponding link is present in both networks.

Strength: the interaction strength between the two nodes or 0 if the link is not present.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Owner	ox1_off_allo Int. Strength	ox1_off Int. Strength	ox1_off_allo Hub1?	ox1_off Hub1?	ox1_off_allo Hub2?	ox1_off Hub2?	ConSurf1	ConSurf2
1	1x53	8x50	ox1_off_allo	100	0	Yes	No	Yes	Yes	9	8
2	1x57	2x40	ox1_off_allo	100	0	No	No	Yes	No	8	9
3	1x58	1x59	ox1_off_allo	100	0	No	No	No	No	3	6
4	1x59	8x61	ox1_off_allo	100	0	No	No	No	No	6	3
5	I1x49	I1x50	ox1_off_allo	100	0	No	No	Yes	Yes	5	8
6	2x42	4x45	ox1_off_allo	100	0	Yes	Yes	No	No	8	6
7	2x50	Na	ox1_off_allo	100	0	Yes	Yes	Yes	No	9	0
8	2x59	E1x52	ox1_off_allo	100	0	No	No	No	No	5	6
9	2x60	2x64	ox1_off_allo	100	0	Yes	No	Yes	No	7	6
10	2x60	7x38	ox1_off_allo	100	0	Yes	No	Yes	Yes	7	7
11	2x66	E1x51	ox1_off_allo	100	0	No	No	No	No	5	3
12	3x33	4x61	ox1_off_allo	100	0	No	No	Yes	No	6	7
13	3x37	4x56	ox1_off_allo	100	0	No	No	No	No	8	6
14	3x47	5x54	ox1_off_allo	100	0	No	No	Yes	No	9	8
15	5x51	5x54	ox1_off_allo	100	0	No	No	Yes	No	6	8
16	5x65	6x30	ox1_off_allo	100	0	No	No	No	No	8	8
17	6x44	Na	ox1_off_allo	100	0	Yes	Yes	Yes	No	9	0
18	6x48	Na	ox1_off_allo	100	0	Yes	Yes	Yes	No	8	0
19	6x50	7x40	ox1_off_allo	100	0	No	No	No	No	9	7
20	7x45	Na	ox1_off_allo	100	0	Yes	Yes	Yes	No	9	0
21	NT.W36	NT.Y41	ox1_off_allo	100	0	No	No	No	No	0	4
22	4x40	4x41	ox1_off_allo	100	0	No	No	No	No	5	7
23	6x51	6x55	ox1_off_allo	100	0	Yes	Yes	No	No	7	7
24	7x28	7x31	ox1_off_allo	100	0	No	No	Yes	No	5	3
25	2x53	3x32	ox1_off_allo	50	0	No	No	Yes	No	8	8
26	I2x52	I2x53	ox1_off_allo	75	0	No	No	No	No	5	7
27	NT.E30	NT.Y34	ox1_off_allo	50	0	No	No	No	No	0	0
28	1x55	1x59	ox1_off_allo	50	0	No	No	No	No	4	6
29	5x58	5x61	ox1_off_allo	50	0	Yes	Yes	No	No	8	9
30	6x49	6x53	ox1_off_allo	0	0	No	No	No	No	6	6
31	1x33	1x36	ox1_off_allo	25	0	No	No	Yes	No	3	7
32	E3.Q329	E3.S331	ox1_off_allo	25	0	No	No	No	No	3	5
33	3x21	E1x50	ox1_off_allo	0	0	No	No	Yes	Yes	8	8
34	E2.V188	E2.V201	ox1_off_allo	0	0	No	No	No	No	1	4
35	2x42	4x42	ox1_off_allo	0	0	Yes	Yes	No	No	8	7
36	NT.L35	NT.L40	ox1_off_allo	50	0	No	No	No	No	0	0
37	NT.Q44	NT.W36	ox1_off_allo	50	0	No	No	No	No	0	0
38	NT.Y41	NT.Y45	ox1_off_allo	50	0	No	No	No	Yes	4	4
39	1x45	7x51	ox1_off_allo	0	0	No	No	No	No	5	7
40	5x66	6x34	ox1_off_allo	0	0	Yes	Yes	No	No	6	7
41	5x68	5x70	ox1_off_allo	25	0	No	No	No	No	7	5
42	NT.E30	NT.S27	ox1_off_allo	50	0	No	No	No	No	0	0
43	2x551	2x56	ox1_off_allo	0	0	No	No	No	No	5	8
44	E2.S187	E2.S200	ox1_off_allo	25	0	No	No	No	No	5	3
45	7x45	I:I:?419	ox1_off_allo	25	0	Yes	Yes	No	No	9	0
46	8x56	8x60	ox1_off_allo	25	0	No	No	No	No	4	9
47	3x30	4x59	ox1_off_allo	0	0	Yes	Yes	No	No	6	5
48	5x44	5x45	ox1_off_allo	25	0	Yes	No	No	No	6	5
49	E2.F199	E2.R197	ox1_off_allo	25	0	Yes	Yes	No	No	3	3
50	NT.L40	NT.Y39	ox1_off_allo	25	0	No	No	No	No	0	0
51	2x45	2x48	ox1_off_allo	0	0	Yes	Yes	No	No	9	5
52	2x41	4x42	ox1_off_allo	0	0	Yes	No	No	No	4	7
53	3x54	3x55	ox1_off_allo	0	0	Yes	Yes	Yes	No	9	7
54	3x55	5x61	ox1_off_allo	0	0	Yes	No	No	No	7	9
55	E2.L192	E2.R195	ox1_off_allo	0	0	No	Yes	No	No	2	2
56	7x27	E3.S331	ox1_off_allo	25	0	No	No	No	No	5	5
57	1x43	1x44	ox1_off_allo	0	0	No	No	No	No	7	5
58	6x24	6x27	ox1_off_allo	25	0	No	No	No	No	4	5
59	E2.E191	E2.L189	ox1_off_allo	25	0	No	No	No	No	1	3
60	5x37	E2.D209	ox1_off_allo	0	0	No	No	No	No	4	4
61	4x43	4x44	ox1_off_allo	0	0	No	No	No	No	4	3
62	1x32	1x36	ox1_off_allo	0	0	No	No	Yes	No	7	7
63	8x55	8x59	ox1_off_allo	0	0	No	No	No	No	5	3
64	7x26	E3.D332	ox1_off_allo	0	0	No	Yes	No	No	3	0
65	5x34	5x37	ox1_off_allo	0	0	No	No	No	No	3	4
66	E2.A207	E2.R205	ox1_off_allo	0	0	No	No	No	No	5	4
67	NT.F31	NT.L32	ox1_off_allo	0	0	No	No	No	No	0	0
68	1x33	1x37	Shared	100	40	No	No	No	No	3	4
69	1x35	1x39	Shared	100	100	No	No	Yes	Yes	5	7
70	1x36	2x65	Shared	100	20	Yes	No	Yes	Yes	7	5
71	1x38	7x39	Shared	100	100	No	No	Yes	Yes	4	7
72	1x39	2x57	Shared	100	100	Yes	Yes	Yes	Yes	7	8
73	1x39	2x60	Shared	100	100	Yes	Yes	Yes	No	7	7
74	1x39	2x61	Shared	100	100	Yes	Yes	No	No	7	7
75	1x39	2x64	Shared	100	100	Yes	Yes	Yes	No	7	6
76	1x39	7x39	Shared	100	100	Yes	Yes	Yes	Yes	7	7
77	1x39	7x42	Shared	100	100	Yes	Yes	Yes	Yes	7	7
78	1x42	7x39	Shared	100	100	No	No	Yes	Yes	7	7
79	1x43	1x47	Shared	100	100	No	No	No	No	7	6
80	1x43	2x57	Shared	100	100	No	No	Yes	Yes	7	8
81	1x46	2x54	Shared	100	100	No	No	No	No	8	7
82	1x47	2x54	Shared	100	100	No	No	No	No	6	7
83	1x49	7x50	Shared	100	100	No	No	No	No	9	9
84	1x50	2x47	Shared	100	100	Yes	Yes	No	No	9	9
85	1x50	2x50	Shared	100	100	Yes	Yes	Yes	Yes	9	9
86	1x50	7x50	Shared	100	100	Yes	Yes	No	No	9	9
87	1x52	8x54	Shared	100	100	Yes	Yes	No	No	6	7
88	1x52	8x57	Shared	100	20	Yes	Yes	No	No	6	6
89	1x53	2x47	Shared	100	100	Yes	No	No	No	9	9
90	1x53	7x50	Shared	100	100	Yes	No	No	No	9	9
91	1x53	7x53	Shared	100	100	Yes	No	Yes	Yes	9	9
92	1x57	2x44	Shared	100	100	No	No	No	No	8	6
93	1x60	I1x49	Shared	100	100	No	No	No	No	6	5
94	1x60	I1x50	Shared	100	100	No	No	Yes	Yes	6	8
95	1x60	8x53	Shared	100	100	No	No	No	Yes	6	7
96	I1x48	I1x51	Shared	100	100	No	No	No	No	6	7
97	2x40	I1x50	Shared	100	100	Yes	No	Yes	Yes	9	8
98	8x49	I1x50	Shared	100	100	No	No	Yes	Yes	6	8
99	8x50	I1x50	Shared	100	100	Yes	Yes	Yes	Yes	8	8
100	2x41	I1x51	Shared	100	100	Yes	No	No	No	4	7
101	2x37	2x40	Shared	100	100	No	No	Yes	No	7	9
102	2x38	3x49	Shared	100	100	No	No	No	Yes	6	9
103	2x39	3x50	Shared	100	100	No	No	No	Yes	8	9
104	2x39	6x37	Shared	100	100	No	No	Yes	Yes	8	8
105	2x40	8x50	Shared	100	100	Yes	No	Yes	Yes	9	8
106	2x41	4x39	Shared	100	40	Yes	No	No	No	4	4
107	2x41	4x43	Shared	100	100	Yes	No	No	No	4	4
108	2x42	3x42	Shared	100	100	Yes	Yes	No	No	8	8
109	2x42	3x45	Shared	100	100	Yes	Yes	No	No	8	7
110	2x42	3x46	Shared	100	100	Yes	Yes	No	No	8	8
111	2x42	4x46	Shared	100	100	Yes	Yes	No	No	8	8
112	2x43	7x53	Shared	100	100	No	No	Yes	Yes	8	9
113	2x45	3x38	Shared	100	100	Yes	Yes	Yes	Yes	9	7
114	2x45	3x42	Shared	100	100	Yes	Yes	No	No	9	8
115	2x45	4x46	Shared	100	100	Yes	Yes	No	No	9	8
116	2x45	4x50	Shared	100	100	Yes	Yes	No	No	9	9
117	2x46	2x50	Shared	100	100	No	No	Yes	Yes	9	9
118	2x46	7x49	Shared	100	100	No	No	Yes	Yes	9	9
119	2x50	7x46	Shared	100	100	Yes	Yes	No	No	9	9
120	2x50	7x49	Shared	100	100	Yes	Yes	Yes	Yes	9	9
121	2x52	3x31	Shared	100	30	No	No	No	Yes	7	6
122	2x56	3x32	Shared	100	100	No	No	Yes	No	8	8
123	2x56	7x42	Shared	100	100	No	No	Yes	Yes	8	7
124	2x57	2x58	Shared	100	100	Yes	Yes	No	No	8	8
125	2x57	7x42	Shared	100	100	Yes	Yes	Yes	Yes	8	7
126	2x60	7x42	Shared	100	100	Yes	No	Yes	Yes	7	7
127	2x61	2x65	Shared	100	100	No	No	Yes	Yes	7	5
128	2x62	E1x52	Shared	100	100	No	No	No	No	5	6
129	2x64	7x35	Shared	100	100	Yes	No	No	No	6	5
130	2x64	7x38	Shared	100	100	Yes	No	Yes	Yes	6	7
131	2x66	E1x49	Shared	100	100	No	No	No	No	5	4
132	2x67	7x31	Shared	100	100	No	No	Yes	No	4	3
133	E1x49	E1x51	Shared	100	100	No	No	No	No	4	3
134	E1x50	E1x52	Shared	100	100	Yes	Yes	No	No	8	6
135	3x25	E1x50	Shared	100	100	No	No	Yes	Yes	9	8
136	3x28	E1x50	Shared	100	100	No	Yes	Yes	Yes	6	8
137	E1x50	E2x50	Shared	100	100	Yes	Yes	No	No	8	9
138	3x22	E2.C185	Shared	100	100	No	No	No	Yes	4	4
139	3x24	3x28	Shared	100	100	No	No	No	Yes	6	6
140	3x25	E2.C185	Shared	100	100	No	No	No	Yes	9	4
141	3x25	E2x50	Shared	100	100	No	No	No	No	9	9
142	3x26	E2.E184	Shared	100	100	No	No	No	No	7	5
143	3x29	4x65	Shared	100	100	No	No	No	No	6	4
144	3x29	Lig	Shared	100	100	No	No	Yes	Yes	6	0
145	3x30	3x31	Shared	100	50	Yes	Yes	No	Yes	6	6
146	3x30	3x34	Shared	100	100	Yes	Yes	No	No	6	6
147	3x30	4x54	Shared	100	100	Yes	Yes	No	No	6	5
148	3x30	4x62	Shared	100	100	Yes	Yes	No	No	6	5
149	3x32	7x42	Shared	100	100	Yes	No	Yes	Yes	8	7
150	3x32	Lig	Shared	100	100	Yes	No	Yes	Yes	8	0
151	3x33	4x57	Shared	100	100	No	No	Yes	Yes	6	8
152	3x34	4x54	Shared	100	100	No	No	No	No	6	5
153	3x36	6x48	Shared	100	100	No	No	Yes	Yes	7	8
154	3x37	4x53	Shared	100	100	No	No	No	No	8	8
155	3x38	4x49	Shared	100	100	Yes	Yes	No	Yes	7	7
156	3x38	4x50	Shared	100	100	Yes	Yes	No	No	7	9
157	3x38	4x53	Shared	100	100	Yes	Yes	No	No	7	8
158	3x40	5x50	Shared	100	100	No	No	No	No	8	9
159	3x40	6x44	Shared	100	100	No	No	Yes	Yes	8	9
160	3x41	4x49	Shared	100	100	No	No	No	Yes	7	7
161	3x43	6x44	Shared	100	100	No	No	Yes	Yes	9	9
162	3x44	5x54	Shared	100	100	No	No	Yes	No	7	8
163	3x45	4x45	Shared	100	100	No	No	No	No	7	6
164	3x45	4x49	Shared	100	100	No	No	No	Yes	7	7
165	3x46	6x37	Shared	100	100	No	No	Yes	Yes	8	8
166	3x47	5x58	Shared	100	100	No	No	Yes	Yes	9	8
167	3x48	3x52	Shared	100	100	No	No	No	Yes	6	5
168	3x49	3x50	Shared	100	100	No	Yes	No	Yes	9	9
169	3x49	I2.S156	Shared	100	100	No	Yes	No	No	9	5
170	3x50	3x53	Shared	100	100	No	Yes	No	No	9	8
171	3x51	3x52	Shared	100	100	Yes	Yes	No	Yes	8	5
172	3x51	3x55	Shared	100	100	Yes	Yes	Yes	No	8	7
173	3x51	3x56	Shared	100	100	Yes	Yes	No	No	8	6
174	3x51	5x57	Shared	100	100	Yes	Yes	No	No	8	7
175	3x51	5x60	Shared	100	100	Yes	Yes	No	No	8	5
176	3x52	I2x53	Shared	100	100	No	Yes	No	No	5	7
177	3x54	5x61	Shared	100	100	Yes	Yes	No	No	9	9
178	3x54	5x65	Shared	100	100	Yes	Yes	No	No	9	8
179	3x54	6x30	Shared	100	100	Yes	Yes	No	No	9	8
180	3x55	3x56	Shared	100	100	Yes	No	No	No	7	6
181	4x38	4x40	Shared	100	30	No	No	No	No	8	5
182	4x38	4x41	Shared	100	100	No	No	No	No	8	7
183	4x56	4x57	Shared	100	100	No	No	Yes	Yes	6	8
184	4x57	5x43	Shared	100	100	Yes	Yes	Yes	Yes	8	6
185	4x61	E2x52	Shared	100	100	Yes	No	Yes	Yes	7	5
186	4x61	5x39	Shared	100	100	Yes	No	Yes	Yes	7	7
187	4x61	Lig	Shared	100	100	Yes	No	Yes	Yes	7	0
188	4x64	E2x52	Shared	100	100	No	No	Yes	Yes	6	5
189	4x64	E2.W206	Shared	100	100	No	No	Yes	Yes	6	7
190	E2.E184	E2.R205	Shared	100	100	No	No	No	No	5	4
191	E2.F199	E2.V188	Shared	100	10	Yes	Yes	No	No	3	1
192	E2.A198	E2.F199	Shared	100	40	No	No	Yes	Yes	4	3
193	6x59	E2x51	Shared	100	100	Yes	Yes	No	No	6	5
194	E2.W206	E2x52	Shared	100	100	Yes	Yes	Yes	Yes	7	5
195	5x40	E2x52	Shared	100	100	No	No	Yes	Yes	6	5
196	6x59	E2x52	Shared	100	100	Yes	Yes	Yes	Yes	6	5
197	5x36	E2.W206	Shared	100	100	No	No	Yes	Yes	5	7
198	5x39	E2.W206	Shared	100	100	Yes	Yes	Yes	Yes	7	7
199	5x35	E2.D208	Shared	100	100	No	No	No	No	4	4
200	5x34	5x38	Shared	100	100	No	No	No	No	3	4
201	5x39	5x40	Shared	100	100	Yes	Yes	No	No	7	6
202	5x39	5x43	Shared	100	100	Yes	Yes	Yes	Yes	7	6
203	5x40	6x59	Shared	100	100	No	No	Yes	Yes	6	6
204	5x41	6x60	Shared	100	100	No	No	No	Yes	6	5
205	5x43	5x461	Shared	100	100	Yes	Yes	No	No	6	6
206	5x43	Lig	Shared	100	100	Yes	Yes	Yes	Yes	6	0
207	5x44	5x47	Shared	100	100	Yes	No	Yes	Yes	6	8
208	5x44	5x48	Shared	100	100	Yes	No	No	No	6	6
209	5x44	6x56	Shared	100	100	Yes	No	No	No	6	6
210	5x47	5x51	Shared	100	100	Yes	Yes	No	No	8	6
211	5x47	6x49	Shared	100	100	Yes	Yes	No	No	8	6
212	5x47	6x52	Shared	100	100	Yes	Yes	No	No	8	7
213	5x54	6x41	Shared	100	100	Yes	No	No	No	8	8
214	5x58	6x37	Shared	100	100	Yes	Yes	Yes	Yes	8	8
215	5x58	6x38	Shared	100	100	Yes	Yes	No	No	8	6
216	5x59	5x63	Shared	100	100	No	No	No	No	3	5
217	5x62	5x66	Shared	100	100	No	No	Yes	Yes	6	6
218	5x65	5x66	Shared	100	100	No	No	Yes	Yes	8	6
219	5x66	6x31	Shared	100	100	Yes	Yes	No	Yes	6	6
220	6x23	I3.T250	Shared	100	100	No	No	No	No	4	3
221	6x23	I3.T251	Shared	100	100	No	No	No	No	4	4
222	6x26	6x30	Shared	100	100	No	No	No	No	6	8
223	6x27	6x31	Shared	100	100	No	No	No	Yes	5	6
224	6x36	7x53	Shared	100	100	No	No	Yes	Yes	8	9
225	6x36	7x56	Shared	100	100	No	No	No	No	8	7
226	6x39	7x52	Shared	100	100	No	No	No	No	7	8
227	6x39	7x56	Shared	100	100	No	No	No	No	7	7
228	6x40	7x49	Shared	100	100	No	No	Yes	Yes	8	9
229	6x40	7x52	Shared	100	100	No	No	No	No	8	8
230	6x42	6x46	Shared	100	30	No	No	No	No	5	5
231	6x43	7x52	Shared	100	100	No	No	No	No	6	8
232	6x44	6x48	Shared	100	100	Yes	Yes	Yes	Yes	9	8
233	6x44	7x45	Shared	100	100	Yes	Yes	Yes	Yes	9	9
234	6x47	7x45	Shared	100	100	No	No	Yes	Yes	8	9
235	6x48	7x41	Shared	100	100	Yes	Yes	No	No	8	7
236	6x48	7x45	Shared	100	100	Yes	Yes	Yes	Yes	8	9
237	6x51	7x37	Shared	100	100	Yes	Yes	No	No	7	6
238	6x51	7x38	Shared	100	100	Yes	Yes	Yes	Yes	7	7
239	6x51	Lig	Shared	100	100	Yes	Yes	Yes	Yes	7	0
240	6x54	7x34	Shared	100	100	No	No	No	Yes	5	5
241	6x54	7x37	Shared	100	100	No	No	No	No	5	6
242	6x55	Lig	Shared	100	100	No	No	Yes	Yes	7	0
243	6x56	6x60	Shared	100	100	No	No	No	Yes	6	5
244	6x57	E3.M326	Shared	100	100	No	No	No	No	5	1
245	6x57	E3.F327	Shared	100	100	No	No	Yes	Yes	5	3
246	6x58	6x59	Shared	100	100	No	No	Yes	Yes	5	6
247	6x60	6x61	Shared	100	100	No	Yes	No	No	5	4
248	E3.F327	E3.M326	Shared	100	100	Yes	Yes	No	No	3	1
249	7x30	E3.F327	Shared	100	100	No	No	Yes	Yes	4	3
250	7x34	E3.F327	Shared	100	100	No	Yes	Yes	Yes	5	3
251	7x34	7x38	Shared	100	100	No	Yes	Yes	Yes	5	7
252	7x36	7x40	Shared	100	100	No	No	No	No	6	7
253	7x38	Lig	Shared	100	100	Yes	Yes	Yes	Yes	7	0
254	7x39	7x40	Shared	100	100	Yes	Yes	No	No	7	7
255	7x39	7x43	Shared	100	100	Yes	Yes	No	No	7	5
256	7x42	Lig	Shared	100	100	Yes	Yes	Yes	Yes	7	0
257	7x45	7x49	Shared	100	100	Yes	Yes	Yes	Yes	9	9
258	7x49	7x53	Shared	100	100	Yes	Yes	Yes	Yes	9	9
259	7x53	8x50	Shared	100	100	Yes	Yes	Yes	Yes	9	8
260	7x54	7x55	Shared	100	100	No	No	No	No	7	5
261	7x54	8x54	Shared	100	100	No	No	No	No	7	7
262	8x47	8x50	Shared	100	100	No	No	Yes	Yes	8	8
263	8x48	8x51	Shared	100	100	No	No	No	No	6	9
264	8x50	8x54	Shared	100	100	Yes	Yes	No	No	8	7
265	NT.K43	NT.Y39	Shared	100	10	No	No	No	No	0	0
266	7x27	7x31	Shared	100	100	No	No	Yes	No	5	3
267	8x60	8x61	Shared	100	10	No	No	No	No	9	3
268	6x51	7x41	Shared	25	100	Yes	Yes	No	No	7	7
269	2x53	3x35	Shared	50	100	No	No	No	No	8	7
270	1x45	7x47	Shared	50	100	No	No	No	No	5	7
271	2x49	3x38	Shared	50	100	No	No	Yes	Yes	8	7
272	3x28	3x29	Shared	50	100	No	Yes	No	No	6	6
273	E3.G325	E3.R328	Shared	50	100	No	No	No	No	2	4
274	NT.D29	NT.R33	Shared	50	20	No	No	No	No	0	0
275	7x35	NT.Y45	Shared	75	30	No	No	No	Yes	5	4
276	7x26	7x29	Shared	50	10	No	Yes	No	No	3	4
277	4x52	4x56	Shared	0	30	No	No	No	No	5	6
278	1x52	8x58	Shared	50	20	Yes	Yes	No	No	6	6
279	3x34	4x57	Shared	0	100	No	No	Yes	Yes	6	8
280	1x56	8x53	Shared	0	100	No	No	No	Yes	7	7
281	7x54	8x51	Shared	50	100	No	No	No	No	7	9
282	3x21	E2.R197	Shared	50	100	No	No	No	No	8	3
283	1x54	2x44	Shared	50	20	No	No	No	No	7	6
284	1x48	1x52	Shared	0	10	No	No	Yes	Yes	4	6
285	3x27	3x31	Shared	0	10	No	No	No	Yes	4	6
286	6x53	6x57	Shared	0	10	No	No	No	No	6	5
287	6x33	6x37	Shared	0	10	No	No	Yes	Yes	8	8
288	3x54	5x64	Shared	0	0	Yes	Yes	No	No	9	5
289	3x39	6x44	Shared	0	0	No	No	Yes	Yes	9	9
290	E2.L189	E2.L192	Shared	50	20	No	No	No	Yes	3	2
291	5x51	6x45	Shared	0	10	No	No	No	No	6	5
292	E2.E191	E2.P190	Shared	50	100	No	No	No	No	1	1
293	2x65	2x66	Shared	0	10	Yes	Yes	No	No	5	5
294	1x50	2x51	Shared	0	20	Yes	Yes	No	No	9	7
295	5x35	E2.W206	Shared	0	20	No	No	Yes	Yes	4	7
296	E2.C185	E2.S200	Shared	25	50	No	Yes	No	No	4	3
297	7x26	E3.S331	Shared	50	50	No	Yes	No	No	3	5
298	NT.L40	NT.W36	Shared	50	10	No	No	No	No	0	0
299	E2.A198	E2.T196	Shared	50	40	No	No	No	No	4	3
300	7x51	7x55	Shared	0	30	No	No	No	No	7	5
301	7x31	7x35	Shared	25	20	Yes	No	No	No	3	5
302	4x41	I2.K155	Shared	50	30	No	No	No	No	7	6
303	2x63	E1x50	Shared	0	0	No	No	Yes	Yes	6	8
304	2x55	2x551	Shared	0	0	No	No	No	No	5	5
305	NT.P42	NT.Y41	Shared	50	30	No	No	No	No	0	4
306	6x25	I3.S252	Shared	25	10	No	No	No	No	4	3
307	8x61	8x62	Shared	25	30	No	No	No	No	3	1
308	4x59	4x60	Shared	25	100	No	No	No	No	5	7
309	6x28	6x32	Shared	25	10	No	Yes	No	No	6	8
310	1x33	1x34	Shared	50	100	No	No	No	No	3	7
311	NT.D38	NT.R37	Shared	25	10	No	No	No	Yes	0	0
312	NT.R37	NT.Y34	Shared	25	100	No	Yes	No	No	0	0
313	5x34	E2.D208	Shared	25	0	No	No	No	No	3	4
314	6x54	7x33	Shared	0	0	No	No	No	No	5	5
315	6x24	6x28	Shared	25	30	No	No	No	Yes	4	6
316	4x48	4x51	Shared	0	0	No	No	No	No	4	4
317	5x49	5x50	Shared	0	30	No	No	No	No	5	9
318	E2.F199	E2.L192	Shared	25	100	Yes	Yes	No	Yes	3	2
319	1x58	I1x51	Shared	25	30	No	No	No	No	3	7
320	E2.A193	E2.S187	Shared	25	30	No	No	No	No	1	5
321	6x43	7x48	Shared	0	0	No	No	No	No	6	6
322	5x70	5x71	Shared	25	50	No	No	No	No	5	3
323	E2.R205	E2.S186	Shared	25	10	No	No	No	No	4	2
324	1x36	1x40	Shared	0	0	Yes	No	No	No	7	3
325	1x51	1x55	Shared	0	0	No	No	No	No	4	4
326	5x52	5x55	Shared	0	0	No	No	No	No	4	5
327	3x26	4x65	Shared	0	0	No	No	No	No	7	4
328	6x35	7x56	Shared	0	40	No	No	No	No	7	7
329	7x32	NT.Y45	Shared	0	20	No	No	No	Yes	2	4
330	NT.E28	NT.L32	Shared	25	30	No	No	No	No	0	0
331	8x51	8x55	Shared	25	20	No	No	No	No	9	5
332	5x38	5x42	Shared	0	0	No	No	No	No	4	4
333	5x53	5x56	Shared	0	0	No	No	No	No	7	5
334	4x47	4x48	Shared	0	0	No	No	No	No	4	4
335	I2x50	I2x51	Shared	0	0	No	No	No	No	9	7
336	5x62	5x63	Shared	0	0	No	No	No	No	6	5
337	6x24	I3.T250	Shared	0	20	No	No	No	No	4	3
338	5x46	5x461	Shared	0	0	No	No	No	No	5	6
339	3x56	I2x50	Shared	0	0	No	No	No	No	6	9
340	5x71	I3.G249	Shared	0	0	No	No	No	No	3	6
341	4x44	4x47	Shared	0	10	No	No	No	No	3	4
342	I3.A253	I3.T251	Shared	0	0	No	No	No	No	0	4
343	8x62	8x63	Shared	0	10	No	No	No	No	1	1
344	1x32	2x65	Shared	0	30	No	No	Yes	Yes	7	5
345	5x70	I3.T250	Shared	0	10	No	No	No	No	5	3
346	7x27	E3.A330	Shared	0	20	No	No	No	No	5	5
347	5x69	6x31	Shared	0	100	No	No	No	Yes	5	6
348	1x43	2x54	ox1_off	0	100	No	No	No	No	7	7
349	1x59	8x53	ox1_off	0	100	No	No	No	Yes	6	7
350	2x60	Lig	ox1_off	0	100	Yes	No	Yes	Yes	7	0
351	E1x50	E2.C185	ox1_off	0	100	Yes	Yes	No	Yes	8	4
352	3x24	E1x52	ox1_off	0	100	No	No	No	No	6	6
353	3x36	Lig	ox1_off	0	100	No	No	Yes	Yes	7	0
354	3x37	4x57	ox1_off	0	100	No	No	Yes	Yes	8	8
355	3x42	4x49	ox1_off	0	100	No	No	No	Yes	8	7
356	4x60	5x39	ox1_off	0	100	No	No	Yes	Yes	7	7
357	5x58	6x41	ox1_off	0	100	Yes	Yes	No	No	8	8
358	6x49	6x50	ox1_off	0	100	No	No	No	No	6	9
359	6x50	7x37	ox1_off	0	100	No	No	No	No	9	6
360	6x58	7x34	ox1_off	0	100	No	No	No	Yes	5	5
361	7x36	7x39	ox1_off	0	100	No	No	Yes	Yes	6	7
362	2x38	I2.S156	ox1_off	0	100	No	No	No	No	6	5
363	NT.W36	NT.Y39	ox1_off	0	100	No	No	No	No	0	0
364	E2.R197	E2.S187	ox1_off	0	100	No	No	No	No	3	5
365	Lig	Lig	ox1_off	0	100	Yes	Yes	Yes	Yes	0	0
366	5x45	5x48	ox1_off	0	40	No	No	No	No	5	6
367	2x59	3x28	ox1_off	0	30	No	No	No	Yes	5	6
368	7x26	7x30	ox1_off	0	50	No	Yes	No	No	3	4
369	3x52	I2x52	ox1_off	0	50	No	Yes	No	No	5	5
370	3x50	3x54	ox1_off	0	30	No	Yes	Yes	Yes	9	9
371	E3.M326	E3.R328	ox1_off	0	20	No	No	No	No	1	4
372	NT.F31	NT.L35	ox1_off	0	30	No	No	No	No	0	0
373	1x54	1x58	ox1_off	0	30	No	No	No	No	7	3
374	NT.Q44	NT.Y45	ox1_off	0	30	No	No	No	Yes	0	4
375	NT.E30	NT.Y27	ox1_off	0	30	No	No	No	No	0	0
376	2x38	4x42	ox1_off	0	30	No	No	No	No	6	7
377	2x52	3x35	ox1_off	0	30	No	No	No	No	7	7
378	E2.L189	NT.R33	ox1_off	0	30	No	No	No	No	3	0
379	E2.N194	E2.T196	ox1_off	0	30	No	No	No	No	0	3
380	7x26	E3.Q329	ox1_off	0	20	No	Yes	No	No	3	3
381	5x64	5x68	ox1_off	0	40	No	No	No	No	5	7
382	2x551	3x31	ox1_off	0	0	No	No	No	Yes	5	6
383	NT.K43	NT.Y45	ox1_off	0	20	No	No	No	Yes	0	4
384	E2.R197	E2.S200	ox1_off	0	20	No	No	No	No	3	3
385	5x37	6x60	ox1_off	0	20	No	No	No	Yes	4	5
386	I2.S156	I2x53	ox1_off	0	30	No	No	No	No	5	7
387	1x57	8x50	ox1_off	0	0	No	No	Yes	Yes	8	8
388	E2.L192	E2.S187	ox1_off	0	40	No	Yes	No	No	2	5
389	1x42	7x47	ox1_off	0	20	No	No	No	No	7	7
390	E2.L189	E2.P190	ox1_off	0	20	No	No	No	No	3	1
391	E2.R195	E2.V188	ox1_off	0	30	No	No	No	No	2	1
392	NT.Y39	NT.Y41	ox1_off	0	30	No	No	No	No	0	4
393	5x66	5x67	ox1_off	0	30	Yes	Yes	No	No	6	4
394	1x54	2x48	ox1_off	0	10	No	No	No	No	7	5
395	5x65	6x34	ox1_off	0	0	No	No	No	No	8	7
396	1x34	NT.Y45	ox1_off	0	20	No	No	No	Yes	7	4
397	E2.L192	NT.E30	ox1_off	0	20	No	Yes	No	No	2	0
398	1x44	1x48	ox1_off	0	0	No	No	No	No	5	4
399	1x59	8x56	ox1_off	0	10	No	No	No	No	6	4
400	NT.L40	NT.R37	ox1_off	0	10	No	No	No	Yes	0	0
401	NT.D26	NT.Y27	ox1_off	0	10	No	No	No	No	0	0
402	E2.L198	NT.R37	ox1_off	0	20	No	No	No	Yes	0	0
403	NT.D29	NT.L32	ox1_off	0	10	No	No	No	No	0	0
404	E2.A207	E2.D208	ox1_off	0	0	No	No	No	No	5	4
405	1x52	1x55	ox1_off	0	0	Yes	Yes	No	No	6	4
406	NT.D38	NT.L35	ox1_off	0	10	No	No	No	No	0	0
407	E2.F199	E2.V201	ox1_off	0	0	Yes	Yes	No	No	3	4
408	8x59	8x63	ox1_off	0	10	No	No	No	No	3	1
409	7x28	NT.K43	ox1_off	0	10	No	No	No	No	5	0
410	6x28	6x31	ox1_off	0	0	No	Yes	No	Yes	6	6
411	8x52	8x53	ox1_off	0	10	No	No	No	Yes	5	7
412	8x58	8x61	ox1_off	0	10	No	No	No	No	6	3
413	6x38	6x42	ox1_off	0	10	No	No	No	No	6	5
414	6x22	I3.T251	ox1_off	0	0	No	No	No	No	0	4
415	E2.A194	E2.E191	ox1_off	0	10	No	No	No	No	1	1
416	4x43	4x47	ox1_off	0	0	No	No	No	No	4	4
417	3x49	4x41	ox1_off	0	10	No	Yes	No	No	9	7
418	5x56	5x60	ox1_off	0	0	No	No	No	No	5	5
419	6x25	6x28	ox1_off	0	0	No	No	No	Yes	4	6
420	5x52	5x56	ox1_off	0	0	No	No	No	No	4	5

Orange: nodes, hubs and links specific of ox1_off_allo network

Green: nodes, hubs and links shared by both networks

Purple: nodes, hubs and links specific of ox1_off network

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Owner: the name of the network the hub belong to or "Shared" if the corresponding hub is present in both networks.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub in the corresponding network.

Num Of Links: the number of links of the corresponding hub in the corresponding network.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Owner	ox1_off_allo Avg Int. Strength	ox1_off Avg Int. Strength	ox1_off_allo Num Of Links	ox1_off Num Of Links	ConSurf
1	1x36	ox1_off_allo	0	0	4	2	7
2	1x53	ox1_off_allo	25	30	4	3	9
3	2x40	ox1_off_allo	25	10	4	3	9
4	2x41	ox1_off_allo	0	0	4	3	4
5	2x60	ox1_off_allo	50	20	4	3	7
6	2x64	ox1_off_allo	50	10	4	3	6
7	3x32	ox1_off_allo	50	40	4	3	8
8	3x55	ox1_off_allo	0	10	4	2	7
9	4x61	ox1_off_allo	25	30	4	3	7
10	5x44	ox1_off_allo	25	40	4	3	6
11	5x54	ox1_off_allo	50	0	4	2	8
12	7x31	ox1_off_allo	0	0	4	3	3
13	Na	ox1_off_allo	75	0	4	0	0
14	1x39	Shared	100	100	7	7	7
15	1x50	Shared	0	20	4	4	9
16	1x52	Shared	0	0	4	5	6
17	I1x50	Shared	50	60	5	4	8
18	2x42	Shared	100	100	6	4	8
19	2x45	Shared	100	80	5	4	9
20	2x50	Shared	100	70	5	4	9
21	2x57	Shared	100	90	4	4	8
22	2x65	Shared	0	0	4	4	5
23	E1x50	Shared	100	100	6	6	8
24	3x30	Shared	50	50	5	4	6
25	3x38	Shared	100	80	5	5	7
26	3x51	Shared	100	100	5	5	8
27	3x54	Shared	25	30	5	5	9
28	4x57	Shared	25	30	4	5	8
29	E2.F199	Shared	0	0	4	4	3
30	E2x52	Shared	100	100	5	5	5
31	E2.W206	Shared	100	100	5	5	7
32	5x39	Shared	75	100	4	5	7
33	5x43	Shared	75	50	4	4	6
34	5x47	Shared	100	90	4	4	8
35	5x58	Shared	75	80	4	4	8
36	5x66	Shared	0	0	4	4	6
37	6x37	Shared	0	10	4	4	8
38	6x44	Shared	100	90	6	5	9
39	6x48	Shared	100	50	5	4	8
40	6x51	Shared	25	70	5	4	7
41	6x59	Shared	100	80	4	4	6
42	E3.F327	Shared	100	90	4	4	3
43	7x38	Shared	100	50	5	4	7
44	7x39	Shared	100	100	5	6	7
45	7x42	Shared	100	100	6	6	7
46	7x45	Shared	100	60	6	4	9
47	7x49	Shared	100	70	5	5	9
48	7x53	Shared	100	80	5	5	9
49	8x50	Shared	100	100	6	6	8
50	Lig	Shared	100	100	8	12	0
51	NT.Y45	ox1_off	0	0	3	5	4
52	3x28	ox1_off	25	40	3	4	6
53	3x31	ox1_off	0	0	3	4	6
54	3x49	ox1_off	0	30	3	4	9
55	3x50	ox1_off	25	30	3	4	9
56	3x52	ox1_off	25	40	3	4	5
57	4x49	ox1_off	0	50	3	4	7
58	E2.C185	ox1_off	0	20	3	4	4
59	E2.L192	ox1_off	0	0	3	4	2
60	6x28	ox1_off	0	0	2	4	6
61	6x31	ox1_off	0	0	3	4	6
62	6x60	ox1_off	0	10	3	4	5
63	7x26	ox1_off	0	0	3	4	3
64	7x34	ox1_off	50	60	3	4	5
65	8x53	ox1_off	0	30	2	4	7
66	NT.R37	ox1_off	0	0	2	4	0

Orange: nodes, hubs and links specific of ox1_off_allo network

Green: nodes, hubs and links shared by both networks

Purple: nodes, hubs and links specific of ox1_off network

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Owner: the name of the network the link belong to or "Shared" if the corresponding link is present in both networks.

Recurrence: the relative Recurrence in the filtered pool of shortest paths.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Owner	ox1_off_allo Recurrence	ox1_off Recurrence	ox1_off_allo Hub1?	ox1_off Hub1?	ox1_off_allo Hub2?	ox1_off Hub2?	ConSurf1	ConSurf2
1	1x36	2x65	ox1_off_allo	12.1153	2.8241	Yes	No	Yes	Yes	7	5
2	2x61	2x65	ox1_off_allo	23.8018	9.84029	No	No	Yes	Yes	7	5
3	1x39	2x64	ox1_off_allo	16.3094	1.93199	Yes	Yes	Yes	No	7	6
4	1x43	2x57	ox1_off_allo	11.8606	3.04645	No	No	Yes	Yes	7	8
5	2x60	7x38	ox1_off_allo	17.3919	0	Yes	No	Yes	Yes	7	7
6	6x51	7x38	ox1_off_allo	34.9747	5.05572	Yes	Yes	Yes	Yes	7	7
7	6x51	7x41	ox1_off_allo	92.9957	6.59047	Yes	Yes	No	No	7	7
8	6x48	7x41	ox1_off_allo	91.7137	6.01155	Yes	Yes	No	No	8	7
9	6x48	Na	ox1_off_allo	13.9407	0	Yes	Yes	Yes	No	8	0
10	2x50	Na	ox1_off_allo	12.8921	0	Yes	Yes	Yes	No	9	0
11	4x56	4x57	ox1_off_allo	99.6604	1.49001	No	No	Yes	Yes	6	8
12	3x37	4x56	ox1_off_allo	99.7368	0	No	No	No	No	8	6
13	2x42	4x42	ox1_off_allo	55.6013	0	Yes	Yes	No	No	8	7
14	2x41	4x42	ox1_off_allo	52.7104	0	Yes	No	No	No	4	7
15	2x41	I1x51	ox1_off_allo	32.2367	5.68345	Yes	No	No	No	4	7
16	1x58	I1x51	ox1_off_allo	26.3106	7.28328	No	No	No	No	3	7
17	1x58	1x59	ox1_off_allo	23.3349	0	No	No	No	No	3	6
18	1x59	8x61	ox1_off_allo	14.3524	0	No	No	No	No	6	3
19	8x50	I1x50	ox1_off_allo	10.5404	7.25887	Yes	Yes	Yes	Yes	8	8
20	7x34	E3.F327	ox1_off_allo	61.1496	8.90073	No	Yes	Yes	Yes	5	3
21	6x57	E3.F327	ox1_off_allo	58.5346	1.65813	No	No	Yes	Yes	5	3
22	6x53	6x57	ox1_off_allo	58.1228	0.833808	No	No	No	No	6	5
23	6x49	6x53	ox1_off_allo	57.3757	0	No	No	No	No	6	6
24	5x47	6x49	ox1_off_allo	56.6583	9.32102	Yes	Yes	No	No	8	6
25	5x47	5x51	ox1_off_allo	49.9724	1.57949	Yes	Yes	No	No	8	6
26	5x51	5x54	ox1_off_allo	48.4272	0	No	No	Yes	No	6	8
27	3x47	5x54	ox1_off_allo	46.1476	0	No	No	Yes	No	9	8
28	3x47	5x58	ox1_off_allo	45.5533	1.59576	No	No	Yes	Yes	9	8
29	2x41	4x43	ox1_off_allo	15.1293	4.07278	Yes	No	No	No	4	4
30	3x34	4x57	ox1_off_allo	16.424	8.06692	No	No	Yes	Yes	6	8
31	3x30	3x34	ox1_off_allo	12.803	6.61216	Yes	Yes	No	No	6	6
32	7x31	7x35	ox1_off_allo	14.8958	3.35828	Yes	No	No	No	3	5
33	4x61	Lig	ox1_off_allo	22.6175	8.21741	Yes	No	Yes	Yes	7	0
34	5x58	5x61	ox1_off_allo	59.5789	0	Yes	Yes	No	No	8	9
35	3x55	5x61	ox1_off_allo	18.7672	0	Yes	No	No	No	7	9
36	3x51	3x55	ox1_off_allo	12.6841	1.59169	Yes	Yes	Yes	No	8	7
37	3x54	5x61	ox1_off_allo	39.2537	1.59576	Yes	Yes	No	No	9	9
38	4x61	E2x52	ox1_off_allo	17.2051	4.41444	Yes	No	Yes	Yes	7	5
39	5x39	E2.W206	ox1_off_allo	23.8188	8.63093	Yes	Yes	Yes	Yes	7	7
40	3x21	E1x50	ox1_off_allo	17.3621	0	No	No	Yes	Yes	8	8
41	3x21	E2.R197	ox1_off_allo	15.8254	0.749749	No	No	No	No	8	3
42	E2.F199	E2.R197	ox1_off_allo	14.467	0	Yes	Yes	No	No	3	3
43	5x35	E2.W206	ox1_off_allo	23.7976	7.88118	No	No	Yes	Yes	4	7
44	5x35	E2.D208	ox1_off_allo	20.4228	6.5742	No	No	No	No	4	4
45	5x34	E2.D208	ox1_off_allo	17.0395	3.95211	No	No	No	No	3	4
46	5x44	5x47	ox1_off_allo	10.8418	6.25695	Yes	No	Yes	Yes	6	8
47	6x27	6x31	ox1_off_allo	20.2148	1.58762	No	No	No	Yes	5	6
48	6x24	6x27	ox1_off_allo	18.4616	0	No	No	No	No	4	5
49	7x54	8x54	ox1_off_allo	15.8891	4.87947	No	No	No	No	7	7
50	NT.Y41	NT.Y45	ox1_off_allo	10.5956	0	No	No	No	Yes	4	4
51	7x27	7x31	ox1_off_allo	10.4725	1.69338	No	No	Yes	No	5	3
52	4x43	4x44	ox1_off_allo	12.1195	0	No	No	No	No	4	3
53	2x57	7x42	ox1_off_allo	11.5252	4.066	Yes	Yes	Yes	Yes	8	7
54	1x39	2x61	Shared	26.1621	11.2354	Yes	Yes	No	No	7	7
55	1x39	7x39	Shared	16.9334	11.2354	Yes	Yes	Yes	Yes	7	7
56	1x39	2x60	Shared	13.2912	11.7303	Yes	Yes	Yes	No	7	7
57	1x39	7x42	Shared	22.5538	11.8387	Yes	Yes	Yes	Yes	7	7
58	2x64	7x38	Shared	39.7334	18.5553	Yes	No	Yes	Yes	6	7
59	7x42	Lig	Shared	36.8086	17.0436	Yes	Yes	Yes	Yes	7	0
60	6x51	Lig	Shared	61.2302	10.8517	Yes	Yes	Yes	Yes	7	0
61	6x48	7x45	Shared	65.8828	50.0651	Yes	Yes	Yes	Yes	8	9
62	7x45	7x49	Shared	63.2466	49.3818	Yes	Yes	Yes	Yes	9	9
63	7x49	7x53	Shared	53.3387	39.9157	Yes	Yes	Yes	Yes	9	9
64	7x53	8x50	Shared	44.5091	34.1644	Yes	Yes	Yes	Yes	9	8
65	8x50	8x54	Shared	24.4216	14.3605	Yes	Yes	No	No	8	7
66	5x43	Lig	Shared	86.5136	94.9117	Yes	Yes	Yes	Yes	6	0
67	4x57	5x43	Shared	92.6349	99.4699	Yes	Yes	Yes	Yes	8	6
68	3x37	4x53	Shared	99.7962	99.9905	No	No	No	No	8	8
69	3x38	4x53	Shared	100	100	Yes	Yes	No	No	7	8
70	2x45	3x38	Shared	65.2927	49.5119	Yes	Yes	Yes	Yes	9	7
71	2x45	3x42	Shared	32.848	24.7322	Yes	Yes	No	No	9	8
72	2x42	3x42	Shared	32.3216	48.7906	Yes	Yes	No	No	8	8
73	2x45	4x46	Shared	32.848	24.7878	Yes	Yes	No	No	9	8
74	2x42	4x46	Shared	32.3216	24.5058	Yes	Yes	No	No	8	8
75	3x38	4x49	Shared	34.3253	50.1464	Yes	Yes	No	Yes	7	7
76	3x45	4x49	Shared	33.247	25.0508	No	No	No	Yes	7	7
77	2x42	3x45	Shared	31.965	24.5397	Yes	Yes	No	No	8	7
78	7x34	7x38	Shared	63.565	10.9331	No	Yes	Yes	Yes	5	7
79	5x58	6x37	Shared	34.7795	12.6996	Yes	Yes	Yes	Yes	8	8
80	2x39	6x37	Shared	19.0262	80.5838	No	No	Yes	Yes	8	8
81	2x39	3x50	Shared	15.9103	79.1101	No	No	No	Yes	8	9
82	2x42	3x46	Shared	49.7517	96.3855	Yes	Yes	No	No	8	8
83	3x46	6x37	Shared	47.3532	94.9646	No	No	Yes	Yes	8	8
84	3x29	Lig	Shared	46.6783	28.9406	No	No	Yes	Yes	6	0
85	3x28	3x29	Shared	37.3222	25.0617	No	Yes	No	No	6	6
86	3x28	E1x50	Shared	34.5035	21.6654	No	Yes	Yes	Yes	6	8
87	2x64	7x35	Shared	29.0572	17.8557	Yes	No	No	No	6	5
88	3x54	5x65	Shared	33.7012	33.1517	Yes	Yes	No	No	9	8
89	5x39	5x43	Shared	22.8722	11.375	Yes	Yes	Yes	Yes	7	6
90	5x65	5x66	Shared	32.1815	30.3221	No	No	Yes	Yes	8	6
91	5x66	6x31	Shared	23.6066	22.5806	Yes	Yes	No	Yes	6	6
92	6x24	I3.T250	Shared	13.1086	10.727	No	No	No	No	4	3
93	7x35	NT.Y45	Shared	13.4313	13.8575	No	No	No	Yes	5	4
94	7x38	Lig	Shared	36.7152	22.9765	Yes	Yes	Yes	Yes	7	0
95	3x36	Lig	ox1_off	0	49.5146	No	No	Yes	Yes	7	0
96	3x36	6x48	ox1_off	1.78715	48.9601	No	No	Yes	Yes	7	8
97	1x57	8x50	ox1_off	0	11.2354	No	No	Yes	Yes	8	8
98	1x57	2x44	ox1_off	3.58704	10.4504	No	No	No	No	8	6
99	3x37	4x57	ox1_off	0	99.9783	No	No	Yes	Yes	8	8
100	3x49	3x50	ox1_off	9.57253	35.8266	No	Yes	No	Yes	9	9
101	3x42	4x49	ox1_off	0	24.7336	No	No	No	Yes	8	7
102	E1x50	E2.C185	ox1_off	0	17.651	Yes	Yes	No	Yes	8	4
103	E2.C185	E2.S200	ox1_off	4.57189	16.3169	No	Yes	No	No	4	3
104	E2.R197	E2.S200	ox1_off	0	15.6078	No	No	No	No	3	3
105	3x49	I2.S156	ox1_off	3.1965	25.1837	No	Yes	No	No	9	5
106	I2.S156	I2x53	ox1_off	0	23.6707	No	No	No	No	5	7
107	3x52	I2x53	ox1_off	3.68892	22.1115	No	Yes	No	No	5	7
108	3x51	3x52	ox1_off	7.34813	17.4178	Yes	Yes	No	Yes	8	5
109	3x50	3x54	ox1_off	0	42.1012	No	Yes	Yes	Yes	9	9
110	E2.R197	E2.S187	ox1_off	0	14.2751	No	No	No	No	3	5
111	E2.L192	E2.S187	ox1_off	0	12.964	No	Yes	No	No	2	5
112	6x51	7x37	ox1_off	3.43422	12.4258	Yes	Yes	No	No	7	6
113	6x50	7x37	ox1_off	0	10.8368	No	No	No	No	9	6
114	6x49	6x50	ox1_off	0	10.0803	No	No	No	No	6	9
115	6x28	6x31	ox1_off	0	18.1363	No	Yes	No	Yes	6	6
116	6x24	6x28	ox1_off	3.68892	12.0678	No	No	No	Yes	4	6
117	2x60	Lig	ox1_off	0	12.2495	Yes	No	Yes	Yes	7	0

Here, those paths that begin and end at given residue pair(s) or that pass through a residue are used to generate a novel metapath. Such a path filtering is particularly recommended if some information on allosteric residues is available. The selection syntax for a residue pair ("Pairs") is C:C:c534,A:A:?600 (the lower-case "c" stands for cytosine and "?" indicates any non standard amino acid or nucleotide residue). Selection of more than one apical residue pair has the following syntax: C:C:c534,A:A:?600,C:C:c534,A:A:E41. Only one residue can be selected as a tail ("Tail"). For midway residue(s), each residue must be separated by a comma as well e.g. A:A:?600,A:A:E41.

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Node1	Node2	Owner	Net1LinkStrength	Net2LinkStrength	Comm1	Comm2	Node1Shell	Node2Shell
1x39	2x57	Shared	5.393	5.86	1	2	2	2
1x39	2x60	Shared	5.342	6.36	1	2	2	1
1x39	2x64	Shared	3.91	4.8875	1	2	2	2
1x39	7x42	Shared	4.366	4.715	1	2	2	1
2x56	3x32	Shared	6.408	8.0125	1	2	2	1
2x56	7x42	Shared	4.03	4.03	1	2	2	1
2x57	7x42	Shared	12.66	14.36	1	2	2	1
2x60	7x42	Shared	9.028	8.9	1	2	1	1
2x60	Lig	ox1_off	5.482	0	1	2	1	0
2x64	7x38	Shared	10.715	9.4525	0	2	2	1
3x28	3x29	Shared	3.39	3.39	0	0	2	1
3x29	4x65	Shared	8.221	8.8075	1	0	1	2
3x29	Lig	Shared	11.682	11.985	1	0	1	0
3x32	7x42	Shared	7.326	8.455	1	2	1	1
3x32	Lig	Shared	18.03	14.66	1	2	1	0
3x33	4x57	Shared	5.957	7.0875	0	0	2	2
3x36	6x48	Shared	5.3	5.995	1	0	1	2
3x36	Lig	ox1_off	3.526	0	1	0	1	0
4x57	5x43	Shared	4.851	5.6	0	0	2	1
4x61	E2x52	Shared	5.734	6.37	1	0	1	2
4x61	5x39	Shared	9.808	9.02	1	0	1	2
4x61	Lig	Shared	8.785	9.5325	1	0	1	0
5x39	5x43	Shared	5.468	4.1275	0	0	2	1
5x43	5x461	Shared	11.543	12.32	1	0	1	2
5x43	Lig	Shared	6.448	11.1975	1	0	1	0
6x48	7x41	Shared	8.453	9.775	1	1	2	2
6x51	7x37	Shared	5.417	4.2575	1	2	1	2
6x51	7x38	Shared	3.846	4.31	1	2	1	1
6x51	7x41	Shared	3.379	3.455	1	2	1	2
6x51	Lig	Shared	10.91	12.175	1	2	1	0
6x55	Lig	Shared	9.142	10.8825	0	2	1	0
7x34	7x38	Shared	3.845	3.675	0	0	2	1
7x38	Lig	Shared	12	11.035	1	2	1	0
7x42	Lig	Shared	4.352	4.8375	1	2	1	0
2x60	2x64	ox1_off_allo	0	3.68	1	2	1	2
2x60	7x38	ox1_off_allo	0	3.8325	1	2	1	1
3x33	4x61	ox1_off_allo	0	3.6675	0	0	2	1
6x51	6x55	ox1_off_allo	0	3.54	1	2	1	1
2x53	3x32	ox1_off_allo	0	3.4125	0	0	2	1

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Difference Members
	Id	Description
	ox1_off_allo	6TOD-OX₁-EMPA-Na 6TOS-OX₁-GSK1059865-Na 6TQ4-OX₁-PubChem 16046844-Na 6TO7-OX₁-Suvorexant-Na
	ox1_off	6TOT-OX₁-Lemborexant 6TP4-OX₁-ACT-462206 6TP6-OX₁-Filorexant 6V9S-OX₁-GTPL11403 6TP3-OX₁-Nemorexant 6TQ6-OX₁-PubChem 145714283 6TQ7-OX₁-SB-334867 6TQ9-OX₁-SB-408124 4ZJC-OX₁-SB-674042 4ZJ8-OX₁-Suvorexant

Network Difference
Value	ox1_off_allo	ox1_off
I_min	3.4675	3.34
Number of Linked Nodes	316	319
Number of Specific Nodes	5 (1.58%)	8 (2.51%)
Number of Shared Nodes	311 (98.42%)	311 (97.49%)
Number of Links	347	353
Number of Specific Links	67 (19.31%)	73 (20.68%)
Number of Shared Links	280 (80.69%)	280 (79.32%)
Number of Hubs	50	53
Number of Specific Hubs	13 (26.00%)	16 (30.19%)
Number of Shared Hubs	37 (74.00%)	37 (69.81%)
Average % Shared Neighbours (Jaccard)	68.95
Average % Shared Neighbours (Otsuka)	76.54
Average % Shared Neighbours (Overlap Coefficient)	84.94
Average % Shared Cliques (k3-6)	61.03
Graphlets Similarity	0.580672

Paths Difference
Value	ox1_off_allo	ox1_off
Number Of Nodes in MetaPath	89	61
Specific Nodes in MetaPath	42 (47.19%)	14 (22.95%)
Shared Nodes in MetaPath	311 (98.42%)	311 (98.42%)
Number Of Links MetaPath	94	64
Specific Links in MetaPath	53 (56.38%)	23 (35.94%)
Shared Links in MetaPath	280 (80.69%)	280 (80.69%)
Number of Shortest Paths	68379	118119
Length Of Smallest Path	3	3
Average Path Length	15.2228	18.2253
Length of Longest Path	35	39
Minimum Path Strength	0.4275	0.2235
Average Path Strength	5.97768	5.47047
Maximum Path Strength	18.4938	17.927
Minimum Path Correlation	0.705	0.7
Average Path Correlation	0.930453	0.920675
Maximum Path Correlation	0.99	0.99
Minimum % Of Corr. Nodes	3.33333	2.94118
Average % Of Corr. Nodes	45.7081	37.8941
Maximum % Of Corr. Nodes	100	100
Minimum Path Hubs %	0	0
Average Path Hubs %	49.3329	53.7568
Maximum Path Hubs %	100	100

Details about the values in these tables can be found in the corresponding documentation page .

You can download a compressed (zip) file with structure(s), 3D outputs (as PyMol and VMD scripts) and numerical data files (as csv and plain text files).

Download ox1_off_ortoallo.zip<

You can click to copy the link of this page to easily come back here later

or use this QR code to link and share this page.

You can also read or download a guide explaining the meaning of all files and numerical data.