Orange: nodes, hubs and links specific of ox2_on_gp network

Green: nodes, hubs and links shared by both networks

Purple: nodes, hubs and links specific of ox2_off network

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Owner: the name of the network the hub belong to or "Shared" if the corresponding hub is present in both networks.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub in the corresponding network.

Num Of Links: the number of links of the corresponding hub in the corresponding network.

ConSurf: this column reports the ConSurf conservation grades of each hub.


Index Hub Owner ox2_on_gp Avg Int. Strength ox2_off Avg Int. Strength ox2_on_gp Num Of Links ox2_off Num Of Links ConSurf
1G.S1.02 ox2_on_gp66.66670406
2G.S1.06 ox2_on_gp66.66670408
3G.s1h1.04 ox2_on_gp33.33330409
4G.s1h1.05 ox2_on_gp00409
5G.S2.06 ox2_on_gp00409
6G.S2.08 ox2_on_gp1000506
7G.S3.01 ox2_on_gp33.33330405
8G.S3.03 ox2_on_gp1000708
9G.S3.04 ox2_on_gp00407
10G.S3.05 ox2_on_gp33.33330608
11G.S3.06 ox2_on_gp1000507
12G.s3h2.03 ox2_on_gp1000509
13G.H2.04 ox2_on_gp33.33330409
14G.H2.06 ox2_on_gp1000609
15G.H2.07 ox2_on_gp1000709
16G.h2s4.01 ox2_on_gp1000609
17G.S4.02 ox2_on_gp1000408
18G.S4.03 ox2_on_gp66.66670507
19G.S4.07 ox2_on_gp33.33330408
20G.s4h3.02 ox2_on_gp33.33330409
21G.s4h3.03 ox2_on_gp00408
22G.s4h3.04 ox2_on_gp1000608
23G.H3.01 ox2_on_gp66.66670409
24G.H3.06 ox2_on_gp00406
25G.H3.09 ox2_on_gp66.66670509
26G.H3.13 ox2_on_gp1000606
27G.H3.14 ox2_on_gp00408
28G.H3.17 ox2_on_gp66.66670505
29G.H3.18 ox2_on_gp33.33330409
30G.S5.05 ox2_on_gp66.66670509
31G.s5hg.01 ox2_on_gp00409
32G.HG.01 ox2_on_gp33.33330406
33G.HG.04 ox2_on_gp33.33330408
34G.HG.07 ox2_on_gp00409
35G.hgh4.02 ox2_on_gp66.66670708
36G.hgh4.04 ox2_on_gp33.33330406
37G.hgh4.08 ox2_on_gp00406
38G.hgh4.11 ox2_on_gp00405
39G.H4.07 ox2_on_gp66.66670405
40G.H4.10 ox2_on_gp1000607
41G.H4.15 ox2_on_gp1000508
42G.S6.02 ox2_on_gp1000408
43G.S6.05 ox2_on_gp66.66670405
44G.H5.05 ox2_on_gp33.33330405
45G.H5.08 ox2_on_gp1000608
46G.H5.17 ox2_on_gp00505
47G.H5.23 ox2_on_gp33.33330404
48b.1x1 ox2_on_gp00404
49b.1x11 ox2_on_gp00408
50b.h2x1 ox2_on_gp33.33330405
51b.lhb1x3 ox2_on_gp33.33330402
52b.lhb1x6 ox2_on_gp66.66670403
53b.l1x3 ox2_on_gp1000409
54b.l1x6 ox2_on_gp66.66670509
55b.b2x1 ox2_on_gp1000408
56b.b2x5 ox2_on_gp1000707
57b.b3x3 ox2_on_gp1000408
58b.l3x1 ox2_on_gp66.66670409
59b.l3x2 ox2_on_gp1000409
60b.b4x6 ox2_on_gp1000709
61b.b5x2 ox2_on_gp33.33330407
62b.b5x3 ox2_on_gp1000409
63b.b5x5 ox2_on_gp1000405
64b.b5x7 ox2_on_gp1000407
65b.l5x1 ox2_on_gp66.66670408
66b.l5x5 ox2_on_gp1000709
67b.b6x5 ox2_on_gp1000606
68b.l6x5 ox2_on_gp1000404
69b.b7x1 ox2_on_gp66.66670504
70b.b8x3 ox2_on_gp1000506
71b.b8x4 ox2_on_gp1000506
72b.l8x3 ox2_on_gp00403
73b.b9x3 ox2_on_gp00406
74b.l9x3 ox2_on_gp1000609
75b.l9x6 ox2_on_gp1000608
76b.b10x5 ox2_on_gp1000609
77b.l10x1 ox2_on_gp33.33330403
78b.b11x2 ox2_on_gp1000407
79b.b11x3 ox2_on_gp66.66670405
80b.l11x2 ox2_on_gp1000509
81b.b12x6 ox2_on_gp1000708
82b.b12x7 ox2_on_gp00409
83b.b13x7 ox2_on_gp1000507
84b.l13x3 ox2_on_gp1000509
85b.l13x6 ox2_on_gp1000409
86b.b14x3 ox2_on_gp33.33330405
87b.b14x5 ox2_on_gp00405
88b.b15x1 ox2_on_gp1000709
89b.b15x2 ox2_on_gp1000406
90b.l15x1 ox2_on_gp66.66670407
91b.l15x2 ox2_on_gp1000409
92b.b16x4 ox2_on_gp1000406
93b.b16x5 ox2_on_gp66.66670405
94b.b16x6 ox2_on_gp1000508
95b.b17x2 ox2_on_gp00403
96b.b17x5 ox2_on_gp66.66670407
97b.b17x7 ox2_on_gp66.66670408
98b.l17x3 ox2_on_gp1000709
99b.l17x6 ox2_on_gp66.66670409
100b.l17x7 ox2_on_gp1000407
101b.b18x3 ox2_on_gp66.66670408
102b.b18x5 ox2_on_gp00405
103b.l18x1 ox2_on_gp1000706
104b.l18x2 ox2_on_gp1000407
105b.b19x2 ox2_on_gp1000606
106b.b19x4 ox2_on_gp1000508
107b.l19x2 ox2_on_gp1000509
108b.b20x2 ox2_on_gp1000406
109b.b20x4 ox2_on_gp1000508
110b.b20x6 ox2_on_gp1000706
111b.b21x1 ox2_on_gp1000507
112b.b21x2 ox2_on_gp00406
113b.b21x5 ox2_on_gp33.33330404
114b.b21x7 ox2_on_gp1000605
115b.b22x5 ox2_on_gp1000507
116b.l22x5 ox2_on_gp1000509
117b.b23x6 ox2_on_gp1000707
118b.l23x1 ox2_on_gp00406
119b.b24x4 ox2_on_gp1000406
120b.b24x6 ox2_on_gp33.33330408
121b.b25x3 ox2_on_gp33.33330405
122b.b25x7 ox2_on_gp1000407
123b.l25x3 ox2_on_gp1000509
124b.l25x6 ox2_on_gp66.66670408
125b.b26x3 ox2_on_gp66.66670506
126b.l27x1 ox2_on_gp1000609
127b.l27x2 ox2_on_gp1000409
128b.b28x3 ox2_on_gp66.66670507
129b.b28x4 ox2_on_gp1000406
130b.b28x6 ox2_on_gp1000509
131g.h1x10 ox2_on_gp00409
132g.h1x11 ox2_on_gp00409
133g.h2x9 ox2_on_gp00404
134g.h2x11 ox2_on_gp1000406
135g.ctx3 ox2_on_gp1000509
136g.ctx4 ox2_on_gp00407
137g.ctx6 ox2_on_gp00506
138g.ctx15 ox2_on_gp66.66670409
139g.ctx16 ox2_on_gp1000608
1401x50 ox2_on_gp1000439
1411x60 ox2_on_gp33.33330536
1422x46 ox2_on_gp33.33330429
1432x50 ox2_on_gp66.66670529
1443x24 ox2_on_gp00415
1453x30 ox2_on_gp025536
1463x38 ox2_on_gp66.666750437
1473x43 ox2_on_gp33.33330429
148I2x51 ox2_on_gp66.66670527
1494x49 ox2_on_gp33.333325436
1506x30 ox2_on_gp33.33330438
1516x38 ox2_on_gp00416
1526x41 ox2_on_gp00418
1536x51 ox2_on_gp66.66670437
1546x60 ox2_on_gp33.33330435
155E3.F333 ox2_on_gp33.333375434
1567x49 ox2_on_gp33.33330439
1571x39 Shared66.6667100567
158I1x50 Shared33.333375448
1592x42 Shared66.6667100458
1602x56 Shared075447
1612x57 Shared66.6667100447
1622x60 Shared0100457
163E1x50 Shared66.6667100467
1643x32 Shared050447
1653x50 Shared33.333350449
1663x51 Shared100100658
1674x61 Shared33.3333100446
168E2x52 Shared100100654
169E2.W214 Shared100100664
1705x39 Shared66.666775558
1715x44 Shared33.333325446
1725x47 Shared10050448
1735x58 Shared10075649
1746x44 Shared10025549
1756x48 Shared66.6667100547
1766x59 Shared33.3333100444
1777x34 Shared33.333350444
1787x38 Shared66.666775445
1797x39 Shared33.333350555
1807x42 Shared100100667
1817x53 Shared10075549
1828x54 Shared025547
183Lig Shared1001001790
184NT.K51 ox2_off00140
1851x31 ox2_off00140
1861x52 ox2_off00246
1872x53 ox2_off00347
1882x551 ox2_off00145
1892x66 ox2_off050345
1903x52 ox2_off025344
1913x56 ox2_off0100356
192I2x53 ox2_off00247
1934x56 ox2_off00345
1944x57 ox2_off66.666725347
195E2.F197 ox2_off00342
196E2.F207 ox2_off00353
1975x40 ox2_off66.666750346
1985x43 ox2_off0100355
1995x66 ox2_off025255
2006x37 ox2_off00248
2017x27 ox2_off025241
2027x40 ox2_off050248
2037x45 ox2_off33.333325349
2048x50 ox2_off66.6667100358
2055x71 ox2_off025050
   
Orange: nodes, hubs and links specific of ox2_on_gp network

Green: nodes, hubs and links shared by both networks

Purple: nodes, hubs and links specific of ox2_off network

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Owner: the name of the network the link belong to or "Shared" if the corresponding link is present in both networks.

Recurrence: the relative Recurrence in the filtered pool of shortest paths.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.


Index Node1 Node2 Owner ox2_on_gp Recurrence ox2_off Recurrence ox2_on_gp Hub1? ox2_off Hub1? ox2_on_gp Hub2? ox2_off Hub2? ConSurf1 ConSurf2
1b.b11x5 b.b14x3 ox2_on_gp23.14660NoNoYesNo65
2b.b10x1 b.b11x5 ox2_on_gp36.77630NoNoNoNo96
3b.b10x1 b.l9x6 ox2_on_gp36.89090NoNoYesNo98
4G.s3h2.03 b.l9x6 ox2_on_gp44.63820YesNoYesNo98
5G.H2.07 G.s3h2.03 ox2_on_gp52.29550YesNoYesNo99
6G.H2.04 G.H2.07 ox2_on_gp52.45470YesNoYesNo99
7G.H2.04 G.H3.08 ox2_on_gp52.64420YesNoNoNo98
8G.H3.08 G.S4.04 ox2_on_gp52.97930NoNoNoNo89
9G.H3.09 G.S4.04 ox2_on_gp53.08830YesNoNoNo99
10G.H3.09 G.H4.15 ox2_on_gp95.59590YesNoYesNo98
11G.H3.02 G.H4.15 ox2_on_gp47.87490NoNoYesNo88
12G.H3.02 G.hgh4.02 ox2_on_gp47.89190NoNoYesNo88
13G.hgh4.01 G.hgh4.02 ox2_on_gp96.95620NoNoYesNo68
14G.hgh4.01 G.s4h3.04 ox2_on_gp97.07650NoNoYesNo68
15G.HG.07 G.s4h3.04 ox2_on_gp99.70290YesNoYesNo98
16G.HG.07 G.s4h3.02 ox2_on_gp49.99460YesNoYesNo99
17G.s4h3.02 G.s5hg.01 ox2_on_gp49.87570YesNoYesNo99
18G.S5.07 G.s5hg.01 ox2_on_gp1000NoNoYesNo99
19G.H1.04 G.S5.07 ox2_on_gp99.79120NoNoNoNo79
20G.H1.04 G.H1.08 ox2_on_gp99.81860NoNoNoNo79
21G.H3.06 G.H4.15 ox2_on_gp47.98260YesNoYesNo68
22G.H3.06 G.hgh4.02 ox2_on_gp47.88920YesNoYesNo68
23G.HG.03 G.HG.07 ox2_on_gp49.86220NoNoYesNo69
24G.HG.03 G.s5hg.01 ox2_on_gp49.87570NoNoYesNo69
25G.S1.03 G.hns1.01 ox2_on_gp10.10120NoNoNoNo94
26G.S3.06 G.h2s4.01 ox2_on_gp10.98460YesNoYesNo79
27G.S1.03 G.S3.06 ox2_on_gp10.22370NoNoYesNo97
28G.H1.08 G.S3.05 ox2_on_gp98.80920NoNoYesNo98
29G.S3.05 G.S4.03 ox2_on_gp98.79440YesNoYesNo87
30G.S1.05 G.h2s4.01 ox2_on_gp12.15180NoNoYesNo99
31G.H3.18 G.S4.02 ox2_on_gp28.78230YesNoYesNo98
32G.S1.05 G.S4.02 ox2_on_gp12.3720NoNoYesNo98
33G.S4.03 G.S5.05 ox2_on_gp99.8720YesNoYesNo79
34G.H3.17 b.l25x6 ox2_on_gp27.31290YesNoYesNo58
35b.b22x1 b.l25x6 ox2_on_gp12.97920NoNoYesNo88
36b.b22x1 b.b22x2 ox2_on_gp12.89130NoNoNoNo88
37b.b22x2 b.b26x3 ox2_on_gp12.7750NoNoYesNo86
38G.S5.03 G.S5.05 ox2_on_gp49.86690NoNoYesNo99
39G.S4.02 G.S5.02 ox2_on_gp41.47680YesNoNoNo86
40G.H5.10 G.S6.02 ox2_on_gp99.68910NoNoYesNo78
41G.H5.10 G.S5.03 ox2_on_gp49.83430NoNoNoNo79
42G.H5.10 G.S6.04 ox2_on_gp49.90150NoNoNoNo79
43G.S5.05 G.S6.04 ox2_on_gp50.01650YesNoNoNo99
44G.H5.13 G.S6.02 ox2_on_gp49.95660NoNoYesNo88
45G.H5.13 G.H5.17 ox2_on_gp49.90310NoNoYesNo85
466x26 G.h4s6.20 ox2_on_gp49.53950NoNoNoNo44
47G.S6.02 G.h4s6.20 ox2_on_gp49.59210YesNoNoNo84
486x30 G.H5.17 ox2_on_gp49.52880YesNoYesNo85
496x26 6x30 ox2_on_gp49.4861.4246NoNoYesNo48
501x53 7x54 ox2_on_gp10.7780NoNoNoNo97
511x53 2x47 ox2_on_gp11.02275.58976NoNoNoNo99
521x50 2x47 ox2_on_gp11.75684.2054YesNoNoNo99
531x50 2x50 ox2_on_gp12.73545.61391YesNoYesNo99
543x43 7x53 ox2_on_gp39.8040YesNoYesYes99
553x50 7x53 ox2_on_gp40.38060YesYesYesYes99
563x50 G.H5.25 ox2_on_gp69.96380YesYesNoNo98
576x33 G.H5.25 ox2_on_gp98.11110NoNoNoNo88
585x65 6x33 ox2_on_gp98.22510NoNoNoNo88
595x65 6x30 ox2_on_gp98.33910NoNoYesNo88
603x50 5x58 ox2_on_gp27.93760YesYesYesYes99
616x37 G.H5.25 ox2_on_gp28.03570NoYesNoNo88
62b.b15x1 b.b16x6 ox2_on_gp12.55450YesNoYesNo98
63b.b16x6 b.b17x3 ox2_on_gp12.42390YesNoNoNo85
64b.b17x3 g.h1x10 ox2_on_gp24.43350NoNoYesNo59
65g.h1x10 g.h1x13 ox2_on_gp17.9140YesNoNoNo91
66b.b17x2 g.h1x13 ox2_on_gp17.67890YesNoNoNo31
67b.b17x2 b.l16x3 ox2_on_gp16.97290YesNoNoNo33
68b.l16x2 b.l16x3 ox2_on_gp16.7390NoNoNoNo93
69b.l14x5 b.l16x2 ox2_on_gp16.50380NoNoNoNo59
70b.l14x3 b.l14x5 ox2_on_gp16.26860NoNoNoNo55
71b.l14x1 b.l14x3 ox2_on_gp16.03340NoNoNoNo45
72b.b18x5 b.l14x1 ox2_on_gp15.79820YesNoNoNo54
73b.b15x2 b.b18x5 ox2_on_gp14.85710YesNoYesNo65
74b.b12x6 b.l9x3 ox2_on_gp11.10380YesNoYesNo89
75b.b11x5 b.l13x7 ox2_on_gp13.53520NoNoNoNo69
76b.l13x3 b.l13x7 ox2_on_gp13.41750YesNoNoNo99
77b.b16x4 b.l13x3 ox2_on_gp12.60320YesNoYesNo69
78b.b21x7 b.b24x6 ox2_on_gp11.29650YesNoYesNo58
79b.b23x6 b.b24x6 ox2_on_gp11.74850YesNoYesNo78
80b.l21x7 b.l23x1 ox2_on_gp14.11190NoNoYesNo56
817x41 7x42 ox2_on_gp12.67060NoNoYesYes77
826x48 7x41 ox2_on_gp14.12371.56546YesYesNoNo77
836x44 6x48 ox2_on_gp62.48946.50328YesYesYesYes97
843x43 6x44 ox2_on_gp24.27434.49918YesNoYesYes99
855x54 6x44 ox2_on_gp48.43580NoNoYesYes89
865x54 5x58 ox2_on_gp48.63610NoNoYesYes89
87E1x49 E1x51 ox2_on_gp10.73210.229385NoNoNoNo54
88E1x51 E1x52 ox2_on_gp11.46020NoNoNoNo46
893x24 E1x52 ox2_on_gp18.74030YesNoNoNo56
903x24 3x28 ox2_on_gp20.9241.46082YesNoNoNo55
913x28 3x32 ox2_on_gp10.83720NoNoYesYes57
92G.H3.15 G.H3.17 ox2_on_gp28.45710NoNoYesNo85
93b.l23x1 b.l25x6 ox2_on_gp14.31940YesNoYesNo68
94b.b23x6 b.l21x7 ox2_on_gp13.51550YesNoNoNo75
95G.H3.09 G.S5.02 ox2_on_gp41.45570YesNoNoNo96
96b.b16x4 b.b17x3 ox2_on_gp12.24420YesNoNoNo65
97b.b14x3 b.b15x1 ox2_on_gp13.29020YesNoYesNo59
98G.H3.15 G.H3.18 ox2_on_gp28.51010NoNoYesNo89
995x58 6x37 Shared27.917929.5143YesYesNoYes98
1003x32 Lig Shared11.571321.5059YesYesYesYes70
1013x36 Lig Shared47.706989.2712NoNoYesYes60
1023x36 6x48 Shared48.059988.8366NoNoYesYes67
1033x28 3x29 Shared10.816771.4395NoNoNoNo55
1043x29 Lig Shared11.540273.3792NoNoYesYes50
1054x61 Lig Shared13.506127.0313YesYesYesYes60
106NT.F39 NT.Y42 ox2_off011.421NoNoNoNo00
107NT.E46 NT.Y42 ox2_off022.8742NoNoNoNo00
108NT.E46 NT.K51 ox2_off020.359NoNoNoYes00
1092x67 NT.K51 ox2_off012.4029NoNoNoYes40
1101x39 2x60 ox2_off028.2506YesYesYesYes77
1112x60 Lig ox2_off0.74910333.2569YesYesYesYes70
1123x28 E1x50 ox2_off069.371NoNoYesYes57
113E1x50 E1x52 ox2_off6.554558.2196YesYesNoNo76
1142x62 E1x52 ox2_off055.9781NoNoNoNo46
1152x62 2x66 ox2_off0.72833755.0243NoNoNoYes45
1162x66 NT.Y42 ox2_off034.5688NoYesNoNo50
1171x39 7x39 ox2_off2.5594727.2607YesYesYesYes75
1181x53 8x54 ox2_off013.8476NoNoYesYes97
1198x50 8x54 ox2_off040.5811NoYesYesYes87
1207x53 8x50 ox2_off065.3185YesYesNoYes98
1217x49 7x53 ox2_off095.1185YesNoYesYes99
1227x45 7x49 ox2_off0.29119100NoYesYesNo99
1236x48 7x45 ox2_off0.051872183.5044YesYesNoYes79
1241x58 2x44 ox2_off013.9201NoNoNoNo36
1251x57 2x44 ox2_off0.24546115.2682NoNoNoNo76
1261x57 I1x50 ox2_off0.49091416.6083NoNoYesYes78
1278x50 I1x50 ox2_off3.189825.7636NoYesYesYes88
1282x551 2x56 ox2_off0.60656214.403NoYesYesYes57
1292x56 3x32 ox2_off0.061872413.1877YesYesYesYes77
1302x39 6x37 ox2_off010.7449NoNoNoYes88
1313x46 6x37 ox2_off040.8548NoNoNoYes88
1322x42 3x46 ox2_off1.465141.8045YesYesNoNo88
1332x42 3x42 ox2_off044.6014YesYesNoNo87
1343x42 4x49 ox2_off0.025129745.2413NoNoYesNo76
1353x38 4x49 ox2_off0.61883247.358YesNoYesNo76
1363x38 4x53 ox2_off0.24899453.2376YesNoNoNo78
1373x37 4x53 ox2_off0.12450154.2638NoNoNoNo78
1383x37 4x56 ox2_off055.2819NoNoNoYes75
1394x56 4x57 ox2_off2.9245159.274NoYesNoYes57
1404x57 5x43 ox2_off1.8270462.5337NoYesNoYes75
1415x43 Lig ox2_off2.1829375.2586NoYesYesYes50
1427x38 Lig ox2_off0.3765318.9746YesYesYesYes50
1432x66 E1x49 ox2_off2.1849810.6322NoYesNoNo55
1443x25 E1x50 ox2_off4.3697610.0527NoNoYesYes97
1453x51 3x55 ox2_off0.24570219.7231YesYesNoNo87
1463x55 5x61 ox2_off021.0029NoNoNoNo79
1475x58 5x61 ox2_off3.4386622.2745YesYesNoNo99
1485x66 6x35 ox2_off036.7741NoYesNoNo58
1496x35 7x56 ox2_off042.5168NoNoNoNo87
1506x36 7x56 ox2_off0.73635143.1848NoNoNoNo87
1516x36 7x53 ox2_off044.2915NoNoYesYes89
1524x60 5x39 ox2_off2.5597614.7732NoNoYesYes68
1534x61 5x39 ox2_off5.843914.4151YesYesYesYes68
1545x39 5x43 ox2_off018.7492YesYesNoYes85
1554x61 E2x52 ox2_off7.299211.916YesYesYesYes64
1565x39 E2.W214 ox2_off2.1904916.1254YesYesYesYes84
157E1x51 NT.E38 ox2_off010.3344NoNoNoNo40
1582x66 E1x51 ox2_off011.4572NoYesNoNo54
1595x35 E2.W214 ox2_off0.73039910.0769NoNoYesYes34
1605x44 5x47 ox2_off4.3988411.1675YesYesYesYes68
1615x47 6x49 ox2_off1.8367317.9404YesYesNoNo86
1626x49 6x50 ox2_off1.1122319.2644NoNoNoNo69
1636x50 7x40 ox2_off0.73209420.5803NoNoNoYes98
1647x39 7x40 ox2_off024.331YesYesNoYes58
1656x27 6x31 ox2_off0.72698217.8398NoNoNoNo45
1665x66 6x31 ox2_off0.97167927.2647NoYesNoNo55
1676x47 7x45 ox2_off0.12339617.6546NoNoNoYes89
1686x54 7x34 ox2_off0.36543211.3928NoNoYesYes54
1697x34 7x38 ox2_off019.6708YesYesYesYes45
1708x61 8x62 ox2_off010.3304NoNoNoNo00
1718x58 8x62 ox2_off011.6946NoNoNoNo00
1721x52 8x58 ox2_off013.0468NoYesNoNo60
1731x52 8x54 ox2_off0.73635118.1979NoYesYesYes67
174NT.F39 NT.L43 ox2_off010.2258NoNoNoNo00
1754x59 4x60 ox2_off2.1941312.3305NoNoNoNo56
1766x47 7x40 ox2_off016.7371NoNoNoYes88

Here, those paths that begin and end at given residue pair(s) or that pass through a residue are used to generate a novel metapath. Such a path filtering is particularly recommended if some information on allosteric residues is available. The selection syntax for a residue pair ("Pairs") is C:C:c534,A:A:?600 (the lower-case "c" stands for cytosine and "?" indicates any non standard amino acid or nucleotide residue). Selection of more than one apical residue pair has the following syntax: C:C:c534,A:A:?600,C:C:c534,A:A:E41. Only one residue can be selected as a tail ("Tail"). For midway residue(s), each residue must be separated by a comma as well e.g. A:A:?600,A:A:E41.

Midway



Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.


2D representation of the interactions of this orthosteric/allosteric ligand.


Node1Node2OwnerNet1LinkStrengthNet2LinkStrengthComm1Comm2Node1ShellNode2Shell
1x392x60ox2_off4.682501321
1x397x42Shared5.46254.31322
2x532x56Shared5.97753.413331022
2x533x32ox2_off3.9401021
2x537x42ox2_off3.4701022
2x563x32Shared6.17.121021
2x567x42Shared3.6956.271022
2x602x64Shared3.97752.891312
2x607x38Shared4.118.216671311
2x607x42Shared10.30257.073331312
2x60LigShared8.114.276671310
2x647x38ox2_off8.50501021
2x677x27ox2_off4.652502021
2x677x31Shared10.102511.22332021
3x28E1x50ox2_off4.40500022
3x294x65Shared8.38753.913330012
3x29LigShared14.053.863330010
3x327x42ox2_off7.047501012
3x32LigShared16.0815.29671010
3x334x57Shared9.7858.026671312
3x334x61Shared6.73256.141311
3x335x43ox2_off5.51501311
3x366x48Shared5.9952.943330012
3x36LigShared4.8410.57330010
4x575x43Shared5.294.981021
4x61E2x52Shared7.9654.246670312
4x615x39Shared9.5853.756670312
4x61LigShared5.363.370310
5x40E2x52Shared9.54259.034322
5x395x40Shared6.5354.716670022
5x395x43ox2_off4.12500021
5x406x55ox2_off6.057504321
5x435x461Shared14.9153.891311
5x43LigShared11.60256.406671310
6x487x41Shared8.834.203337522
6x517x37Shared5.8054.130312
6x517x41Shared3.4553.586670312
6x51LigShared13.545.706670310
6x55LigShared11.269.913330010
7x277x31Shared8.7456.862311
7x347x38ox2_off3.957500321
7x38LigShared14.90757.786671310
3x283x29Shared3.393.953330021
E2.F207E2.V209ox2_off2.947500021
7x27NT.H49ox2_off2.5402312
2x63E1x50ox2_off2.4500012
7x27E3.T336ox2_off2.262502311
E3.A334E3.H335Shared0.3651.463330012
2x63Ligox2_on_gp05.056670010
3x283x32ox2_on_gp03.203330021
3x33Ligox2_on_gp05.166671310
4x65E2x52ox2_on_gp03.610022
6x517x38ox2_on_gp05.303330311
7x31Ligox2_on_gp07.892310
7x387x42ox2_on_gp05.443331312
7x417x42ox2_on_gp04.210022
5x461Ligox2_on_gp03.183330310
7x27Ligox2_on_gp06.016672310
E3.T336Ligox2_on_gp02.283330010
E2.V209Ligox2_on_gp02.113330010
2x593x32ox2_on_gp02.023330021
7x26E3.T336ox2_on_gp01.446670021
E2.S194E2.V209ox2_on_gp01.080021
E3.A334Ligox2_on_gp00.520010

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Difference Members
Id Description
ox2_on_gp 7L1V-OX2-PubChem 155491009-chim(NtGi1-Gs-CtGq)/β1/γ2
7SQO-OX2-TAK-925-Gi1/β1/γ2
7L1U-OX2-Orexin-chim(NtGi1-Gs-CtGq)/β1/γ2
ox2_off 5WQC-OX2-EMPA
6TPN-OX2-HTL6641
7XRR-OX2-Lemborexant
6TPJ-OX2-Suvorexant
Network Difference
Value ox2_on_gp ox2_off
Imin 2.86667 3.4025
Number of Linked Nodes 907 322
Number of Specific Nodes 623 (68.69%) 38  (11.80%)
Number of Shared Nodes 284 (31.31%) 284  (88.20%)
Number of Links 1103 351
Number of Specific Links 922 (83.59%) 170  (48.43%)
Number of Shared Links 181 (16.41%) 181  (51.57%)
Number of Hubs 183 49
Number of Specific Hubs 156 (85.25%) 22  (44.90%)
Number of Shared Hubs 27 (14.75%) 27  (55.10%)
Average % Shared Neighbours (Jaccard) 13.16
Average % Shared Neighbours (Otsuka) 16.18
Average % Shared Neighbours (Overlap Coefficient) 19.30
Average % Shared Cliques (k3-6) 51.09
Graphlets Similarity 0.675685
Paths Difference
Value ox2_on_gp ox2_off
Number Of Nodes in MetaPath 100 77
Specific Nodes in MetaPath 86 (86.00%) 63  (81.82%)
Shared Nodes in MetaPath 284 (31.31%) 284  (31.31%)
Number Of Links MetaPath 105 78
Specific Links in MetaPath 98 (93.33%) 71  (91.03%)
Shared Links in MetaPath 181 (16.41%) 181  (16.41%)
Number of Shortest Paths 12757241 61089
Length Of Smallest Path 3 3
Average Path Length 49.4722 15.0486
Length of Longest Path 74 37
Minimum Path Strength 0.72 0.49
Average Path Strength 4.71712 5.97843
Maximum Path Strength 20.9667 19.79
Minimum Path Correlation 0.703333 0.7025
Average Path Correlation 0.995975 0.924255
Maximum Path Correlation 1 0.99
Minimum % Of Corr. Nodes 1.47059 2.85714
Average % Of Corr. Nodes 24.8077 46.2346
Maximum % Of Corr. Nodes 100 100
Minimum Path Hubs % 0 0
Average Path Hubs % 57.5156 45.7495
Maximum Path Hubs % 100 100

Details about the values in these tables can be found in the corresponding documentation page .

You can download a compressed (zip) file with structure(s), 3D outputs (as PyMol and VMD scripts) and numerical data files (as csv and plain text files).

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