Orange: nodes, hubs and links specific of peptide_on_gp network

Green: nodes, hubs and links shared by both networks

Purple: nodes, hubs and links specific of peptide_off network

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Owner: the name of the network the hub belong to or "Shared" if the corresponding hub is present in both networks.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub in the corresponding network.

Num Of Links: the number of links of the corresponding hub in the corresponding network.

ConSurf: this column reports the ConSurf conservation grades of each hub.


Index Hub Owner peptide_on_gp Avg Int. Strength peptide_off Avg Int. Strength peptide_on_gp Num Of Links peptide_off Num Of Links ConSurf
1G.HN.11 peptide_on_gp00602
2G.S1.02 peptide_on_gp49.47050405
3G.S1.06 peptide_on_gp33.06020408
4G.s1h1.04 peptide_on_gp10.14490409
5G.H1.01 peptide_on_gp19.56520509
6G.S2.03 peptide_on_gp4.130430409
7G.S2.04 peptide_on_gp4.347830406
8G.S2.06 peptide_on_gp10.86960509
9G.S2.08 peptide_on_gp42.44150505
10G.S3.03 peptide_on_gp90.78590607
11G.S3.04 peptide_on_gp39.66830406
12G.S3.06 peptide_on_gp69.48160505
13G.S3.07 peptide_on_gp8.695650509
14G.H2.06 peptide_on_gp94.84390609
15G.H2.07 peptide_on_gp92.60480609
16G.h2s4.01 peptide_on_gp79.62650509
17G.S4.04 peptide_on_gp31.36180409
18G.s4h3.04 peptide_on_gp61.28210608
19G.H3.01 peptide_on_gp32.21850509
20G.H3.06 peptide_on_gp14.42030506
21G.H3.09 peptide_on_gp85.86960709
22G.H3.13 peptide_on_gp45.9420505
23G.H3.17 peptide_on_gp92.10140605
24G.H3.18 peptide_on_gp59.0580409
25G.S5.04 peptide_on_gp43.86230509
26G.S5.05 peptide_on_gp82.34060709
27G.S5.07 peptide_on_gp19.42030509
28G.s5hg.01 peptide_on_gp7.971010409
29G.HG.07 peptide_on_gp20.65220409
30G.HG.14 peptide_on_gp00405
31G.hgh4.02 peptide_on_gp63.60090507
32G.hgh4.05 peptide_on_gp61.80710607
33G.hgh4.08 peptide_on_gp4.347830503
34G.H4.10 peptide_on_gp48.9130506
35G.H4.12 peptide_on_gp21.01450405
36G.H4.15 peptide_on_gp65.5240408
37G.h4s6.02 peptide_on_gp13.86010408
38G.h4s6.12 peptide_on_gp2.347830404
39G.S6.02 peptide_on_gp90.79710707
40G.S6.05 peptide_on_gp49.53620504
41G.H5.03 peptide_on_gp44.38410508
42G.H5.08 peptide_on_gp76.88410508
43G.H5.23 peptide_on_gp39.42030404
44G.H5.26 peptide_on_gp12.68120505
45b.1x4 peptide_on_gp00408
46b.1x11 peptide_on_gp00408
47b.h2x1 peptide_on_gp00405
48b.lhb1x3 peptide_on_gp20.28990602
49b.lhb1x11 peptide_on_gp28.26090504
50b.b1x6 peptide_on_gp20.28990409
51b.l1x3 peptide_on_gp98.55070609
52b.l1x6 peptide_on_gp24.24640409
53b.b2x1 peptide_on_gp74.61540508
54b.b2x5 peptide_on_gp99.74920607
55b.b3x3 peptide_on_gp24.34780408
56b.l3x1 peptide_on_gp15.50720409
57b.l3x2 peptide_on_gp46.0580509
58b.b4x3 peptide_on_gp28.40580407
59b.b4x5 peptide_on_gp23.84060407
60b.b4x6 peptide_on_gp1000709
61b.b5x2 peptide_on_gp2.173910407
62b.b5x3 peptide_on_gp91.01450609
63b.b5x5 peptide_on_gp54.27540405
64b.b5x7 peptide_on_gp76.30430407
65b.l5x1 peptide_on_gp78.07410508
66b.l5x5 peptide_on_gp99.27540709
67b.b6x5 peptide_on_gp83.52170606
68b.l6x5 peptide_on_gp35.6990404
69b.b7x1 peptide_on_gp65.04350504
70b.l7x4 peptide_on_gp00409
71b.b8x4 peptide_on_gp99.71020506
72b.l8x3 peptide_on_gp00403
73b.l8x5 peptide_on_gp2.173910503
74b.b9x3 peptide_on_gp10.68840506
75b.l9x3 peptide_on_gp94.0290609
76b.l9x6 peptide_on_gp99.27540808
77b.b10x5 peptide_on_gp55.02790509
78b.b11x4 peptide_on_gp45.28990409
79b.l11x2 peptide_on_gp84.77480409
80b.b12x6 peptide_on_gp99.53620608
81b.b12x7 peptide_on_gp5.072460409
82b.b13x7 peptide_on_gp96.90910507
83b.l13x3 peptide_on_gp1000609
84b.l13x6 peptide_on_gp60.49890509
85b.l13x7 peptide_on_gp49.18060409
86b.b14x3 peptide_on_gp29.13040405
87b.b15x1 peptide_on_gp79.78150509
88b.b15x2 peptide_on_gp47.43590406
89b.b15x3 peptide_on_gp32.17390409
90b.l15x1 peptide_on_gp43.50610407
91b.l15x2 peptide_on_gp66.13990509
92b.b16x4 peptide_on_gp94.11930406
93b.b16x5 peptide_on_gp35.36790405
94b.b16x6 peptide_on_gp1000708
95b.b17x7 peptide_on_gp74.84390408
96b.l17x3 peptide_on_gp99.13040609
97b.l17x6 peptide_on_gp65.31770409
98b.b18x3 peptide_on_gp74.26420408
99b.l18x1 peptide_on_gp95.65220806
100b.l18x2 peptide_on_gp62.27420407
101b.l18x3 peptide_on_gp19.56520405
102b.b19x2 peptide_on_gp92.39130506
103b.b19x4 peptide_on_gp60.54290408
104b.l19x2 peptide_on_gp80.340509
105b.b20x4 peptide_on_gp97.9710508
106b.b20x6 peptide_on_gp95.65220506
107b.b20x7 peptide_on_gp23.9130509
108b.l20x2 peptide_on_gp32.60870509
109b.b21x1 peptide_on_gp77.04570607
110b.b21x4 peptide_on_gp00405
111b.b21x5 peptide_on_gp11.23190404
112b.b21x7 peptide_on_gp89.90520605
113b.l21x2 peptide_on_gp5.79710404
114b.b22x5 peptide_on_gp51.94820507
115b.l22x5 peptide_on_gp87.17390609
116b.b23x6 peptide_on_gp93.47830707
117b.l23x1 peptide_on_gp34.96380406
118b.b24x4 peptide_on_gp64.72410406
119b.b24x6 peptide_on_gp46.65830408
120b.l24x2 peptide_on_gp10.14490406
121b.l25x3 peptide_on_gp98.04350509
122b.l25x6 peptide_on_gp61.66670408
123b.b26x3 peptide_on_gp22.75360406
124b.l27x1 peptide_on_gp1000709
125b.l27x2 peptide_on_gp58.44040409
126b.b28x3 peptide_on_gp40.02790507
127b.b28x4 peptide_on_gp92.70070406
128b.b28x6 peptide_on_gp98.38350609
129g.l1x4 peptide_on_gp13.76810408
130g.h2x11 peptide_on_gp55.80710406
131g.ctx3 peptide_on_gp86.81880509
132g.ctx6 peptide_on_gp18.47830406
133g.ctx14 peptide_on_gp29.91920409
134g.ctx15 peptide_on_gp34.42590409
135g.ctx16 peptide_on_gp80.43480708
1361x59 peptide_on_gp00425
1372x46 peptide_on_gp31.75592.77778429
1383x33 peptide_on_gp26.08713.8889436
1393x43 peptide_on_gp11.95650428
1405x62 peptide_on_gp4.347830416
1416x44 peptide_on_gp38.681241.6667439
1426x51 peptide_on_gp46.637731.25437
1436x52 peptide_on_gp28.589729.8611437
1447x38 peptide_on_gp24.637714.5833416
1457x42 peptide_on_gp57.998957.6389437
1468x50 peptide_on_gp44.202956.9444439
147E1 peptide_on_gp6.086964.16667410
148H.HA.16 peptide_on_gp4.347830500
149H.hahb.06 peptide_on_gp6.521740500
150H.HB.02 peptide_on_gp6.521740400
151H.HB.10 peptide_on_gp4.347830400
152H.hchd.01 peptide_on_gp6.521740400
153H.HD.07 peptide_on_gp4.347830500
154H.hehf.04 peptide_on_gp8.695650400
155H.HF.03 peptide_on_gp8.695650400
156NT Shared36.521716.6667853
1571x39 Shared42.256435.4167447
1581x60 Shared15.9424.16667756
1592x40 Shared24.17398.33333449
1602x42 Shared62.391360.4167658
1612x50 Shared76.050733.3333559
162E1x50 Shared66.884190.9722668
163E1x52 Shared25.133838.8889556
1643x37 Shared49.386827.0833457
1653x50 Shared53.659455.5556569
1663x51 Shared47.017850458
1673x56 Shared04.16667456
168E2 Shared95.652210020163
1695x58 Shared78.91325549
1706x48 Shared96.376892.7083668
171E3 Shared63.623241.66671293
1727x49 Shared46.137112.5549
1737x53 Shared61.594235.7639659
174Lig Shared98.550710025170
1751x31 peptide_off8.695652.77778351
1761x50 peptide_off20.289922.9167349
1772x41 peptide_off2.1739110.4167345
1783x31 peptide_off4.347830345
1795x39 peptide_off24.275429.8611248
1806x27 peptide_off00154
   
Orange: nodes, hubs and links specific of peptide_on_gp network

Green: nodes, hubs and links shared by both networks

Purple: nodes, hubs and links specific of peptide_off network

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Owner: the name of the network the link belong to or "Shared" if the corresponding link is present in both networks.

Recurrence: the relative Recurrence in the filtered pool of shortest paths.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.


Index Node1 Node2 Owner peptide_on_gp Recurrence peptide_off Recurrence peptide_on_gp Hub1? peptide_off Hub1? peptide_on_gp Hub2? peptide_off Hub2? ConSurf1 ConSurf2
1b.l2x3 b.l2x5 peptide_on_gp27.25320NoNoNoNo85
2b.b3x1 b.l2x3 peptide_on_gp27.04240NoNoNoNo58
3b.b3x1 b.b6x5 peptide_on_gp26.83160NoNoYesNo56
4b.b3x3 b.b6x5 peptide_on_gp13.71020YesNoYesNo86
5b.b3x2 b.b4x6 peptide_on_gp10.00620NoNoYesNo59
6b.b2x3 b.b3x2 peptide_on_gp10.17910NoNoNoNo65
7b.b26x2 b.b2x3 peptide_on_gp47.20850NoNoNoNo76
8b.b26x1 b.b26x2 peptide_on_gp47.41480NoNoNoNo97
9b.b26x1 b.l27x1 peptide_on_gp47.62130NoNoYesNo99
10b.l1x6 b.l27x1 peptide_on_gp43.34530YesNoYesNo99
11b.l1x6 b.l3x1 peptide_on_gp43.85330YesNoYesNo99
12b.l3x1 b.l5x5 peptide_on_gp87.79910YesNoYesNo99
13b.b2x1 b.l27x1 peptide_on_gp43.34520YesNoYesNo89
14b.b2x1 b.l3x1 peptide_on_gp43.74940YesNoYesNo89
15G.h2s4.01 b.l5x5 peptide_on_gp44.01050YesNoYesNo99
16G.H2.07 G.h2s4.01 peptide_on_gp45.19670YesNoYesNo99
17G.H2.04 G.H2.07 peptide_on_gp99.96090NoNoYesNo99
18G.H2.04 G.H3.08 peptide_on_gp99.9810NoNoNoNo99
19G.H3.08 G.S4.04 peptide_on_gp1000NoNoYesNo99
20G.S4.04 G.S5.04 peptide_on_gp94.00440YesNoYesNo99
21G.S5.04 G.S5.06 peptide_on_gp92.55780YesNoNoNo98
22G.S5.06 G.s4h3.01 peptide_on_gp92.93030NoNoNoNo87
23G.HG.04 G.s4h3.01 peptide_on_gp92.9530NoNoNoNo97
24G.HG.04 G.s4h3.04 peptide_on_gp92.97580NoNoYesNo98
25G.HG.07 G.s4h3.04 peptide_on_gp96.13150YesNoYesNo98
26G.HG.07 G.s4h3.02 peptide_on_gp96.17940YesNoNoNo99
27G.s4h3.02 G.s5hg.01 peptide_on_gp96.12610NoNoYesNo99
28G.S5.07 G.s5hg.01 peptide_on_gp96.29860YesNoYesNo99
29G.H1.04 G.S5.07 peptide_on_gp47.90430NoNoYesNo79
30G.H1.04 G.S5.05 peptide_on_gp47.93350NoNoYesNo79
31G.H5.07 G.S5.05 peptide_on_gp11.46480NoNoYesNo89
32G.H5.07 G.S4.03 peptide_on_gp11.38480NoNoNoNo87
33b.l5x5 b.l7x2 peptide_on_gp43.98170YesNoNoNo99
34G.H2.07 b.l7x2 peptide_on_gp44.07370YesNoNoNo99
35G.S5.07 G.s6h5.01 peptide_on_gp48.37480YesNoNoNo99
36G.S5.05 G.s6h5.01 peptide_on_gp47.89260YesNoNoNo99
37G.H2.07 b.l9x6 peptide_on_gp33.8720YesNoYesNo98
38G.H2.06 b.l9x6 peptide_on_gp30.19160YesNoYesNo98
39G.H2.06 b.l17x6 peptide_on_gp14.9990YesNoYesNo99
40G.H2.06 b.b18x1 peptide_on_gp14.99910YesNoNoNo99
41G.S5.03 G.S5.05 peptide_on_gp44.57470NoNoYesNo89
42b.l25x6 b.l27x1 peptide_on_gp38.30460YesNoYesNo89
43G.H5.10 G.S5.03 peptide_on_gp44.46070NoNoNoNo68
44G.H5.10 G.S6.02 peptide_on_gp88.79810NoNoYesNo67
45G.S5.05 G.S6.04 peptide_on_gp44.57470YesNoNoNo99
46G.H5.10 G.S6.04 peptide_on_gp44.46070NoNoNoNo69
47G.S6.02 G.h4s6.12 peptide_on_gp87.0130YesNoYesNo74
483x50 G.H5.25 peptide_on_gp84.11660YesYesNoNo97
49G.H5.20 G.H5.25 peptide_on_gp85.03290NoNoNoNo97
50G.H5.20 G.H5.26 peptide_on_gp85.40470NoNoYesNo95
51G.H5.21 G.H5.26 peptide_on_gp86.14760NoNoYesNo55
52G.H5.21 G.h4s6.12 peptide_on_gp86.27130NoNoYesNo54
533x50 7x53 peptide_on_gp51.0730YesYesYesYes99
54b.l17x6 b.l19x1 peptide_on_gp15.09460YesNoNoNo99
55b.l17x5 b.l19x1 peptide_on_gp29.89260NoNoNoNo69
56b.l17x5 b.l19x2 peptide_on_gp29.75740NoNoYesNo69
57b.l17x3 b.l19x2 peptide_on_gp20.5330YesNoYesNo99
58b.b19x4 b.l17x3 peptide_on_gp11.44410YesNoYesNo89
59b.b17x7 b.b20x6 peptide_on_gp23.14580YesNoYesNo86
60b.b17x7 b.b21x1 peptide_on_gp22.32590YesNoYesNo87
61b.1x19 b.b21x1 peptide_on_gp18.71180NoNoYesNo67
62b.1x15 b.1x19 peptide_on_gp15.80940NoNoNoNo76
63b.1x12 b.1x15 peptide_on_gp15.39470NoNoNoNo67
64b.1x12 g.h1x11 peptide_on_gp14.97990NoNoNoNo69
65b.1x11 g.h1x11 peptide_on_gp13.73550YesNoNoNo89
66b.b18x1 b.l19x1 peptide_on_gp14.93320NoNoNoNo99
67b.b20x4 b.b20x6 peptide_on_gp16.2580YesNoYesNo86
68b.1x10 b.1x11 peptide_on_gp10.41590NoNoYesNo18
69b.1x10 b.1x6 peptide_on_gp10.00080NoNoNoNo13
70b.l2x5 b.l4x2 peptide_on_gp27.66450NoNoNoNo54
71b.l4x2 g.ctx16 peptide_on_gp27.41970NoNoYesNo48
72b.b2x4 b.b6x5 peptide_on_gp12.16240NoNoYesNo66
73b.b10x4 b.b2x4 peptide_on_gp11.94980NoNoNoNo66
74b.b2x5 b.l4x1 peptide_on_gp31.39750YesNoNoNo75
75b.l4x1 g.ctx16 peptide_on_gp31.19220NoNoYesNo58
76b.b3x3 b.b4x3 peptide_on_gp11.58150YesNoYesNo87
77b.l23x1 b.l25x6 peptide_on_gp23.00350YesNoYesNo68
78b.l21x7 b.l23x1 peptide_on_gp22.61610NoNoYesNo56
79b.b23x6 b.l21x7 peptide_on_gp21.56120YesNoNoNo75
80b.b23x6 b.b24x6 peptide_on_gp18.8290YesNoYesNo78
81b.b21x7 b.b24x6 peptide_on_gp18.42850YesNoYesNo58
82b.b22x1 b.l25x6 peptide_on_gp15.12480NoNoYesNo88
83b.b22x1 b.b22x2 peptide_on_gp14.94650NoNoNoNo88
84b.b22x2 b.b26x3 peptide_on_gp14.74010NoNoYesNo86
853x36 Lig peptide_on_gp48.76130.381424NoNoYesYes70
863x36 6x48 peptide_on_gp49.11370.71173NoNoYesYes78
873x43 7x53 peptide_on_gp21.65010YesNoYesYes89
885x54 6x44 peptide_on_gp20.75450NoNoYesNo89
895x54 5x58 peptide_on_gp20.81090NoNoYesYes89
903x50 5x58 peptide_on_gp25.69440YesYesYesYes99
91E2 Lig peptide_on_gp14.29970YesYesYesYes30
92b.b2x3 b.b2x5 peptide_on_gp36.82350NoNoYesNo67
936x44 6x48 Shared40.699991.8289YesNoYesYes98
943x43 6x44 Shared20.756890.0201YesNoYesNo89
956x48 7x45 Shared20.365851.5631YesYesNoNo89
967x45 7x49 Shared20.628849.6677NoNoYesYes99
977x49 7x53 Shared26.47633.6204YesYesYesYes99
981x35 1x39 peptide_off0.15395913.8728NoNoYesYes47
991x39 2x57 peptide_off1.2487835.3506YesYesNoNo77
1002x57 7x42 peptide_off1.805239.676NoNoYesNo77
1012x60 7x42 peptide_off0.19901242.6133NoNoYesNo77
1021x35 7x35 peptide_off0.42267811.3444NoNoNoNo45
1031x39 7x39 peptide_off0.42526613.0117YesYesNoNo77
1041x50 2x50 peptide_off1.1245310.4715NoYesYesYes99
1052x50 7x49 peptide_off4.9919317.5494YesYesYesYes99
1066x48 Lig peptide_off0100YesYesYesYes80
1072x60 Lig peptide_off0.46773243.211NoNoYesYes70
1081x57 2x44 peptide_off0.42338315.9372NoNoNoNo76
1091x54 2x44 peptide_off0.28227718.387NoNoNoNo76
1101x54 2x48 peptide_off0.14114519.5981NoNoNoNo76
1112x48 4x50 peptide_off020.8014NoNoNoNo69
1122x45 4x50 peptide_off0.41938535.7281NoNoNoNo99
1132x45 3x42 peptide_off0.03104888.5809NoNoNoNo98
1142x46 3x42 peptide_off1.3886189.0685YesNoNoNo98
1152x46 3x43 peptide_off0.83743789.5482YesNoYesNo98
1161x57 2x40 peptide_off0.56446314.7065NoNoYesYes79
1171x60 I1x50 peptide_off1.9760610.0822YesYesNoNo68
1182x40 I1x50 peptide_off2.1169111.3444YesYesNoNo98
1192x45 4x46 peptide_off0.54498669.781NoNoNoNo97
1202x42 4x46 peptide_off0.67845669.0339YesYesNoNo87
1212x42 4x42 peptide_off0.69449913.283YesYesNoNo87
1222x41 4x42 peptide_off0.55564812.123NoYesNoNo57
1233x46 6x37 peptide_off057.0564NoNoNoNo98
1242x42 3x46 peptide_off2.9269757.9844YesYesNoNo89
1254x61 Lig peptide_off1.6169435.1028NoNoYesYes70
1264x61 5x39 peptide_off1.2132835.4528NoNoNoYes78
1275x39 E2 peptide_off029.2045NoYesYesYes83
128E1x50 E2 peptide_off4.7848221.8277YesYesYesYes83
129E1x50 E1x52 peptide_off6.3318811.8242YesYesYesYes86
1304x65 Lig peptide_off029.6331NoNoYesYes60
1314x65 E2x52 peptide_off0.40461129.1377NoNoNoNo65
132E2 E2x52 peptide_off0.0016273628.1664YesYesNoNo35
1333x38 4x50 peptide_off0.27961115.5204NoNoNoNo89
1343x38 4x53 peptide_off0.13981213.0117NoNoNoNo88
1353x37 4x53 peptide_off011.7455YesYesNoNo78
1365x58 6x37 peptide_off1.4886249.3099YesYesNoNo98
1375x58 5x61 peptide_off040.7691YesYesNoNo99
1383x51 5x61 peptide_off022.9916YesYesNoNo89
1393x51 3x55 peptide_off0.41265811.2422YesYesNoNo87
1406x48 6x52 peptide_off7.5680617.9977YesYesYesNo87
1415x47 6x52 peptide_off3.2320511.7455NoNoYesNo87
1421x42 7x39 peptide_off010.4715NoNoNoNo77
1437x53 8x50 peptide_off023.3023YesYesYesNo99
1443x54 5x61 peptide_off0.14108119.1774NoNoNoNo99
1458x50 8x54 peptide_off020.1722YesNoNoNo97
1467x54 8x54 peptide_off016.8299NoNoNoNo87
1473x54 5x65 peptide_off013.7824NoNoNoNo99
1485x65 6x31 peptide_off012.5241NoNoNoNo96
1497x54 8x51 peptide_off015.6266NoNoNoNo89
150E3 Lig peptide_off3.9242813.3145YesYesYesYes30

Here, those paths that begin and end at given residue pair(s) or that pass through a residue are used to generate a novel metapath. Such a path filtering is particularly recommended if some information on allosteric residues is available. The selection syntax for a residue pair ("Pairs") is C:C:c534,A:A:?600 (the lower-case "c" stands for cytosine and "?" indicates any non standard amino acid or nucleotide residue). Selection of more than one apical residue pair has the following syntax: C:C:c534,A:A:?600,C:C:c534,A:A:E41. Only one residue can be selected as a tail ("Tail"). For midway residue(s), each residue must be separated by a comma as well e.g. A:A:?600,A:A:E41.

Midway



Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.


2D representation of the interactions of this orthosteric/allosteric ligand.


Node1Node2OwnerNet1LinkStrengthNet2LinkStrengthComm1Comm2Node1ShellNode2Shell
2x60LigShared6.580976.631951210
3x29LigShared5.876535.428661210
3x32LigShared12.64685.591051210
3x33LigShared4.681945.78041210
4x61LigShared5.384723.300221210
6x51LigShared6.016396.578511210
6x55LigShared11.5918.30861210
6x58LigShared6.328687.990851210
7x34LigShared5.3392410.35451210
7x38LigShared5.227675.226210210
NTNTShared7.638443.650741211
1x357x35Shared3.746634.476360022
2x607x42Shared4.030142.884451212
2x63E1x50Shared6.522994.903860212
E1x49E2Shared7.955945.371981221
E1x50E2Shared3.746283.054021221
3x22E2Shared9.560145.938661221
3x294x65Shared8.840498.592961211
3x366x48Shared7.434834.371011211
3x406x44peptide_off6.4629900022
4x615x39Shared5.167993.129281212
4x64E2Shared9.787858.405131221
4x65E2x52Shared4.049035.279511011
E2E2Shared54.914848.58461211
E2E2x51Shared8.96678.442441211
E2E2x52Shared5.75174.813911211
5x36E2Shared8.27847.559820021
5x35E2Shared8.967786.31441221
5x39E2peptide_off3.9331601021
5x395x43peptide_off5.0450301021
5x406x59Shared6.453095.147531012
6x446x48Shared12.72628.137130021
6x486x52Shared4.717083.088011012
6x487x41Shared8.12175.014771012
6x487x45Shared6.377747.861551012
6x516x55Shared6.398446.467731211
6x547x34Shared6.084066.069920021
E3E3Shared6.557478.482641211
1x352x64peptide_off3.6715300021
3x334x61Shared5.708375.850391211
3x36LigShared4.242083.997811210
4x65Ligpeptide_off3.7774701010
E2NTShared3.990876.307391211
6x48Ligpeptide_off4.4799301010
7x30E3Shared3.679972.693081021
3x334x57Shared3.549933.553781212
6x517x37peptide_off3.5197901212
6x57E3Shared3.444653.088691021
6x576x61peptide_off3.3015601022
5x40Ligpeptide_off3.2268401010
2x563x32Shared3.183654.511120021
E3LigShared2.778968.587151210
7x317x35peptide_off2.4360800212
1x32E1peptide_off2.1720800221
5x345x35peptide_off2.1566300222
5x33E3peptide_off2.0293800021
2x67E1x49peptide_off1.909100022
5x32E2peptide_off1.7547900021
7x277x30peptide_off1.5739600012
6x586x62peptide_off1.3840301212
7x26E3Shared1.215382.465991221
7x24NTShared1.184031.063040021
7x28NTpeptide_off1.0627400021
6x63E3Shared0.8520830.3267831021
7x25E3peptide_off0.71722200021
5x31E2Shared0.4665280.8813760021
1x277x32peptide_off0.38388900022
1x247x27peptide_off0.36472200221
5x29E2peptide_off0.33361100021
2x68E2Shared0.23750.3027540021
1x221x25peptide_off0.11416700021
2x607x38peptide_on_gp02.935221211
2x63Ligpeptide_on_gp05.190870210
2x64Ligpeptide_on_gp03.119790210
E2Ligpeptide_on_gp017.18691210
E2x51Ligpeptide_on_gp05.951760210
E2x52Ligpeptide_on_gp04.472881210
6x516x52peptide_on_gp03.989091212
6x517x41peptide_on_gp03.55071212
6x547x37peptide_on_gp03.087490022
6x58E3peptide_on_gp03.085471211
6x61E3peptide_on_gp04.895790021
7x347x38peptide_on_gp04.14821211
7x387x42peptide_on_gp04.133740212
2x647x35peptide_on_gp03.269220212
5x43Ligpeptide_on_gp04.672880010
7x31Ligpeptide_on_gp07.299140210
LigNTpeptide_on_gp03.562371201
E1Ligpeptide_on_gp03.755420210
3x333x37peptide_on_gp03.094131212
3x406x48peptide_on_gp04.268730021
E2E3peptide_on_gp03.325181211
5x406x55peptide_on_gp02.841081011
7x32NTpeptide_on_gp02.084220221
7x287x32peptide_on_gp02.058190022
7x27Ligpeptide_on_gp01.99940010
5x325x35peptide_on_gp01.861230022
2x67E2peptide_on_gp01.76620021
1x32NTpeptide_on_gp01.635580221
5x34E2peptide_on_gp01.456820221
6x62E2peptide_on_gp01.366670021
5x335x34peptide_on_gp00.6540130022
7x257x26peptide_on_gp00.6086520022
5x27E2peptide_on_gp00.3926090221
5x29E3peptide_on_gp00.2898910021
5x28E2peptide_on_gp00.2577540221
3x29Ca5peptide_on_gp00.2495221212
2x69E1peptide_on_gp00.2241010021
1x25Ligpeptide_on_gp00.1938040010
1x24NTpeptide_on_gp00.1919570221
3x20E1peptide_on_gp00.1732320021
1x277x31peptide_on_gp00.1396740021
6x65E3peptide_on_gp00.09521740021
2x70E1peptide_on_gp00.005652170021

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Difference Members
Id Description
peptide_on_gp cck_on_gp
angiotensin_on_gp
apelin_on_gp
bombesin_on_gp
bradykinin_on_gp
compl-peptide_on_gp
endothelin_on_gp
formylpeptide_on_gp
galanin_on_gp
ghrelin_on_gp
kisspeptin_on_gp
melanocortin_on_gp
motilin_on_gp
neuromedin-u_on_gp
npy_on_gp
neurotensin_on_gp
opioid_on_gp
orexin_on_gp
relaxin_on_gp
somatostatin_on_gp
tachykinin_on_gp
trh_on_gp
vasop-oxy_on_gp
peptide_off cck_off
angiotensin_off
bombesin_off
endothelin_off
ghrelin_off
npy_off
opioid_off
orexin_off
somatostatin_off
tachykinin_off
vasop-oxy_off
neurotensin_off
Network Difference
Value peptide_on_gp peptide_off
Imin 2.8668 3.66285
Number of Linked Nodes 1150 309
Number of Specific Nodes 845 (73.48%) 4  (1.29%)
Number of Shared Nodes 305 (26.52%) 305  (98.71%)
Number of Links 1319 319
Number of Specific Links 1124 (85.22%) 124  (38.87%)
Number of Shared Links 195 (14.78%) 195  (61.13%)
Number of Hubs 174 25
Number of Specific Hubs 155 (89.08%) 6  (24.00%)
Number of Shared Hubs 19 (10.92%) 19  (76.00%)
Average % Shared Neighbours (Jaccard) 12.51
Average % Shared Neighbours (Otsuka) 14.70
Average % Shared Neighbours (Overlap Coefficient) 17.00
Average % Shared Cliques (k3-6) 75.71
Graphlets Similarity 0.388369
Paths Difference
Value peptide_on_gp peptide_off
Number Of Nodes in MetaPath 92 58
Specific Nodes in MetaPath 83 (90.22%) 49  (84.48%)
Shared Nodes in MetaPath 305 (26.52%) 305  (26.52%)
Number Of Links MetaPath 97 58
Specific Links in MetaPath 92 (94.85%) 53  (91.38%)
Shared Links in MetaPath 195 (14.78%) 195  (14.78%)
Number of Shortest Paths 9727898 48990
Length Of Smallest Path 3 3
Average Path Length 41.9825 14.2843
Length of Longest Path 72 30
Minimum Path Strength 0.293725 0.548264
Average Path Strength 5.08667 4.88222
Maximum Path Strength 21.0849 10.424
Minimum Path Correlation 0.700056 0.700729
Average Path Correlation 0.987352 0.901728
Maximum Path Correlation 1 0.986111
Minimum % Of Corr. Nodes 1.49254 3.57143
Average % Of Corr. Nodes 23.3242 39.1703
Maximum % Of Corr. Nodes 100 100
Minimum Path Hubs % 0 0
Average Path Hubs % 54.4746 29.9091
Maximum Path Hubs % 100 100

Details about the values in these tables can be found in the corresponding documentation page .

You can download a compressed (zip) file with structure(s), 3D outputs (as PyMol and VMD scripts) and numerical data files (as csv and plain text files).

Download peptide_off_on_gp.zip<



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