psnGPCR

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Orange: nodes, hubs and links specific of rhodopsin_off network

Green: nodes, hubs and links shared by both networks

Purple: nodes, hubs and links specific of rhodopsin_on network

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Owner: the name of the network the link belong to or "Shared" if the corresponding link is present in both networks.

Strength: the interaction strength between the two nodes or 0 if the link is not present.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Owner	rhodopsin_off Int. Strength	rhodopsin_on Int. Strength	rhodopsin_off Hub1?	rhodopsin_on Hub1?	rhodopsin_off Hub2?	rhodopsin_on Hub2?	ConSurf1	ConSurf2
1	E3.D282	NT.N2	rhodopsin_off	10.77	0	No	No	No	No	2	6
2	NT.N15	NT.T4	rhodopsin_off	4.87333	0	No	No	No	No	7	6
3	E2.T193	NT.E5	rhodopsin_off	10.82	0	No	Yes	No	No	5	6
4	E2.Y192	NT.Y10	rhodopsin_off	10.9233	0	Yes	Yes	No	Yes	5	7
5	NT.Q28	NT.V11	rhodopsin_off	4.3	0	Yes	No	No	Yes	5	8
6	E2.Q184	NT.P12	rhodopsin_off	4.74	0	Yes	Yes	No	No	3	8
7	NT.F13	NT.Y30	rhodopsin_off	5.84333	0	No	No	Yes	Yes	4	4
8	NT.P23	NT.S22	rhodopsin_off	4.15333	0	Yes	Yes	Yes	No	5	5
9	NT.F24	NT.S22	rhodopsin_off	4.4	0	Yes	No	Yes	No	5	5
10	NT.P23	NT.Q28	rhodopsin_off	6.84667	0	Yes	Yes	Yes	No	5	5
11	3x21	NT.F24	rhodopsin_off	4.51667	0	No	No	Yes	No	8	5
12	3x22	NT.F24	rhodopsin_off	13	0	No	No	Yes	No	3	5
13	3x25	NT.F24	rhodopsin_off	4.19333	0	No	No	Yes	No	9	5
14	2x67	NT.Y29	rhodopsin_off	4.35	0	No	No	Yes	No	4	4
15	NT.L31	NT.Y30	rhodopsin_off	7.42333	0	Yes	No	Yes	Yes	4	4
16	1x32	2x67	rhodopsin_off	4.51667	0	No	No	No	No	5	4
17	1x35	2x64	rhodopsin_off	5.00667	0	No	No	No	No	5	5
18	1x35	7x39	rhodopsin_off	15.4233	0	No	No	Yes	No	5	5
19	1x39	2x61	rhodopsin_off	4.24	0	Yes	No	No	No	7	6
20	1x39	7x39	rhodopsin_off	5.39333	0	Yes	No	Yes	No	7	5
21	1x47	1x51	rhodopsin_off	5.36	0	Yes	No	No	No	6	4
22	1x52	8x54	rhodopsin_off	5.18333	0	No	No	Yes	No	6	6
23	1x54	2x44	rhodopsin_off	4.61333	0	No	No	No	No	7	5
24	1x56	8x50	rhodopsin_off	5.67667	0	No	No	Yes	Yes	7	8
25	1x59	1x60	rhodopsin_off	8.65333	0	Yes	No	Yes	No	5	5
26	1x59	8x57	rhodopsin_off	7.08667	0	Yes	No	No	No	5	5
27	1x59	CT.K339	rhodopsin_off	9.94667	0	Yes	No	No	No	5	5
28	1x60	8x57	rhodopsin_off	5.93333	0	Yes	No	No	No	5	5
29	1x60	CT.V337	rhodopsin_off	5.07333	0	Yes	No	No	No	5	5
30	1x60	CT.S338	rhodopsin_off	8.37	0	Yes	No	No	No	5	9
31	CT.V337	I1x49	rhodopsin_off	9.61333	0	No	No	No	No	5	5
32	2x40	I1x50	rhodopsin_off	10.5267	0	No	No	Yes	Yes	8	7
33	8x49	I1x50	rhodopsin_off	3.99	0	Yes	No	Yes	Yes	6	7
34	8x53	I1x50	rhodopsin_off	6.35	0	No	No	Yes	Yes	5	7
35	2x41	I1x51	rhodopsin_off	4.11667	0	Yes	No	No	No	5	6
36	4x39	I1x51	rhodopsin_off	5.42667	0	No	No	No	No	2	6
37	2x38	3x49	rhodopsin_off	10.4767	0	Yes	No	No	No	6	8
38	2x38	I2x56	rhodopsin_off	4.33	0	Yes	No	Yes	No	6	7
39	2x39	6x33	rhodopsin_off	7.45	0	No	No	No	No	8	8
40	2x40	7x53	rhodopsin_off	6.2	0	No	No	Yes	Yes	8	9
41	2x41	4x43	rhodopsin_off	8.06	0	Yes	No	No	No	5	3
42	2x42	3x42	rhodopsin_off	5.16	0	No	Yes	No	No	7	8
43	2x43	6x40	rhodopsin_off	5.65333	0	No	No	No	Yes	8	8
44	2x43	7x53	rhodopsin_off	16.8033	0	No	No	Yes	Yes	8	9
45	2x46	7x49	rhodopsin_off	8.69667	0	No	No	No	No	9	9
46	2x52	3x31	rhodopsin_off	4.29	0	No	No	Yes	No	6	4
47	2x53	3x35	rhodopsin_off	4.65667	0	No	No	No	No	7	8
48	2x551	3x31	rhodopsin_off	9.53333	0	No	No	Yes	No	4	4
49	2x59	3x27	rhodopsin_off	5.40333	0	No	No	No	No	5	4
50	2x60	3x28	rhodopsin_off	11.29	0	No	No	No	No	7	5
51	2x62	E1x51	rhodopsin_off	6.30667	0	No	No	Yes	No	4	4
52	2x62	E1x52	rhodopsin_off	14.0967	0	No	No	No	No	4	7
53	2x66	E1x51	rhodopsin_off	6	0	No	No	Yes	No	4	4
54	E1x50	E2.P180	rhodopsin_off	4.33333	0	No	Yes	Yes	No	8	3
55	E1x51	E1x52	rhodopsin_off	7.86667	0	Yes	No	No	No	4	7
56	3x26	4x61	rhodopsin_off	5.49333	0	No	No	No	No	7	5
57	3x28	7x42	rhodopsin_off	8.55	0	No	No	Yes	No	5	7
58	3x28	Lig	rhodopsin_off	4.91667	0	No	No	Yes	Yes	5	0
59	3x33	Lig	rhodopsin_off	8.78	0	No	No	Yes	Yes	4	0
60	3x36	6x48	rhodopsin_off	4.69	0	No	No	Yes	Yes	7	8
61	3x37	3x40	rhodopsin_off	6.63	0	Yes	Yes	No	No	6	7
62	3x41	5x50	rhodopsin_off	13.06	0	Yes	Yes	No	No	5	9
63	3x42	4x49	rhodopsin_off	5.86667	0	No	No	No	No	8	7
64	3x43	6x41	rhodopsin_off	4.47	0	No	No	No	No	8	8
65	3x43	6x44	rhodopsin_off	4.46333	0	No	No	Yes	Yes	8	9
66	3x45	4x45	rhodopsin_off	4.29333	0	No	No	No	No	7	6
67	3x46	6x37	rhodopsin_off	8.44333	0	No	No	No	No	9	8
68	3x49	3x50	rhodopsin_off	8.53	0	No	No	Yes	No	8	9
69	3x50	3x53	rhodopsin_off	5.23333	0	Yes	No	No	No	9	8
70	3x50	6x30	rhodopsin_off	6.59	0	Yes	No	No	No	9	7
71	3x50	6x33	rhodopsin_off	7.84667	0	Yes	No	No	No	9	8
72	3x50	6x34	rhodopsin_off	12.0767	0	Yes	No	No	No	9	6
73	3x50	6x37	rhodopsin_off	7.40667	0	Yes	No	No	No	9	8
74	3x54	5x64	rhodopsin_off	4.23	0	No	No	No	No	8	6
75	3x54	5x65	rhodopsin_off	6.95	0	No	No	No	No	8	8
76	3x55	5x60	rhodopsin_off	4.07333	0	No	No	No	No	7	4
77	4x59	5x39	rhodopsin_off	6.26	0	No	No	Yes	Yes	7	6
78	4x60	5x39	rhodopsin_off	6.74	0	No	Yes	Yes	Yes	5	6
79	5x38	E2.W175	rhodopsin_off	4.94	0	No	No	No	Yes	4	5
80	E2.P180	E2x50	rhodopsin_off	5.65	0	Yes	No	No	Yes	3	9
81	6x51	E2.E181	rhodopsin_off	9.72667	0	Yes	Yes	Yes	Yes	6	4
82	7x34	E2.E181	rhodopsin_off	9.92333	0	Yes	No	Yes	Yes	4	4
83	7x39	E2.S186	rhodopsin_off	5.72333	0	Yes	No	No	No	5	5
84	E2.Y191	E2x52	rhodopsin_off	5.64	0	Yes	Yes	No	Yes	6	4
85	E2.Y192	E3.F283	rhodopsin_off	4.13	0	Yes	Yes	No	Yes	5	4
86	7x34	E2.Y192	rhodopsin_off	3.99	0	Yes	No	Yes	Yes	4	5
87	5x37	E2.P194	rhodopsin_off	6.29	0	Yes	No	No	No	3	1
88	E2.P194	E3.Q279	rhodopsin_off	5.26333	0	No	No	No	No	1	1
89	5x36	E2.H195	rhodopsin_off	5.95333	0	Yes	Yes	Yes	No	4	4
90	5x36	E2.T198	rhodopsin_off	5.85	0	Yes	Yes	No	No	4	1
91	5x37	E3.Q279	rhodopsin_off	9.77	0	Yes	No	No	No	3	1
92	5x40	6x59	rhodopsin_off	15.2933	0	No	No	No	No	4	4
93	5x43	5x44	rhodopsin_off	4.97333	0	No	Yes	No	No	5	5
94	5x44	6x56	rhodopsin_off	6.43	0	No	No	No	No	5	6
95	5x47	Lig	rhodopsin_off	6.35333	0	No	Yes	Yes	Yes	8	0
96	5x54	6x41	rhodopsin_off	5.12	0	No	No	No	No	8	8
97	5x58	6x38	rhodopsin_off	5.64333	0	No	No	No	No	9	5
98	5x65	6x31	rhodopsin_off	9.61333	0	No	No	Yes	No	8	4
99	5x65	6x34	rhodopsin_off	4.76	0	No	No	No	No	8	6
100	5x67	6x35	rhodopsin_off	5.04	0	No	No	No	No	4	7
101	5x70	I3.E239	rhodopsin_off	5.03	0	No	No	Yes	No	4	2
102	5x71	5x72	rhodopsin_off	6.82667	0	No	No	No	No	2	5
103	6x25	I3.Q238	rhodopsin_off	5.67	0	No	No	No	No	4	5
104	6x27	I3.E239	rhodopsin_off	9.34667	0	No	No	Yes	No	4	2
105	6x28	I3.E239	rhodopsin_off	13.05	0	No	No	Yes	No	4	2
106	6x31	I3.E239	rhodopsin_off	5.4	0	Yes	No	Yes	No	4	2
107	6x23	6x27	rhodopsin_off	5.77333	0	No	No	No	No	4	4
108	6x27	6x31	rhodopsin_off	6.78	0	No	No	Yes	No	4	4
109	6x28	6x31	rhodopsin_off	6.22333	0	No	No	Yes	No	4	4
110	6x39	7x56	rhodopsin_off	5.83333	0	No	No	No	No	5	7
111	6x40	7x49	rhodopsin_off	4.67667	0	No	Yes	No	No	8	9
112	6x48	7x41	rhodopsin_off	6.48333	0	Yes	Yes	No	No	8	8
113	6x48	7x45	rhodopsin_off	8.23667	0	Yes	Yes	No	No	8	9
114	6x51	7x34	rhodopsin_off	7.98333	0	Yes	Yes	Yes	No	6	4
115	6x54	7x33	rhodopsin_off	8.74	0	No	No	No	No	5	4
116	6x54	7x34	rhodopsin_off	6.59333	0	No	No	Yes	No	5	4
117	6x54	7x37	rhodopsin_off	6.48	0	No	No	No	No	5	6
118	6x57	7x33	rhodopsin_off	5.84667	0	No	No	No	No	4	4
119	6x61	E3.S281	rhodopsin_off	4.18333	0	No	No	No	No	3	4
120	7x39	7x42	rhodopsin_off	9.1	0	Yes	No	Yes	No	5	7
121	7x48	7x49	rhodopsin_off	15.8933	0	No	Yes	No	No	5	9
122	7x53	8x47	rhodopsin_off	5.04	0	Yes	Yes	Yes	No	9	8
123	7x53	8x50	rhodopsin_off	28.8833	0	Yes	Yes	Yes	Yes	9	8
124	7x54	8x54	rhodopsin_off	6.31667	0	No	Yes	Yes	No	7	6
125	8x47	8x49	rhodopsin_off	4.4	0	Yes	No	Yes	No	8	6
126	8x48	8x51	rhodopsin_off	4.12333	0	Yes	No	No	No	4	8
127	8x48	8x52	rhodopsin_off	5.13	0	Yes	No	No	No	4	5
128	8x48	CT.E332	rhodopsin_off	4.95	0	Yes	No	Yes	No	4	5
129	8x49	CT.E332	rhodopsin_off	5.94667	0	Yes	No	Yes	No	6	5
130	8x56	CT.S338	rhodopsin_off	5.33	0	No	No	No	No	4	9
131	8x56	CT.E341	rhodopsin_off	5.64333	0	No	No	Yes	No	4	5
132	CT.E341	CT.K325	rhodopsin_off	9.9	0	Yes	No	No	No	5	3
133	CT.L328	CT.N326	rhodopsin_off	5.95	0	No	No	No	No	4	3
134	CT.D331	CT.P327	rhodopsin_off	4.83	0	No	No	No	No	4	5
135	CT.E332	CT.S334	rhodopsin_off	7.18333	0	Yes	No	No	No	5	6
136	CT.T336	CT.T342	rhodopsin_off	4.18667	0	No	No	Yes	No	7	6
137	CT.E341	CT.S338	rhodopsin_off	11.98	0	Yes	No	No	No	5	9
138	CT.E341	CT.T342	rhodopsin_off	5.17333	0	Yes	No	Yes	No	5	6
139	CT.Q344	CT.T342	rhodopsin_off	6.61667	0	No	No	Yes	No	5	6
140	CT.P347	CT.V345	rhodopsin_off	4.12333	0	No	No	No	No	4	8
141	8x49	I1x49	rhodopsin_off	7.68333	0	Yes	No	No	No	6	5
142	CT.P327	CT.T342	rhodopsin_off	4.08	0	No	No	Yes	No	5	6
143	E2.I179	E2.P180	rhodopsin_off	3.95333	0	No	No	Yes	No	1	3
144	6x36	8x47	rhodopsin_off	3.73667	0	No	No	Yes	No	8	8
145	2x53	2x57	rhodopsin_off	3.73333	0	No	No	Yes	Yes	7	7
146	7x35	E2.G182	rhodopsin_off	3.64	0	No	No	No	No	4	3
147	3x47	5x57	rhodopsin_off	3.61	0	No	No	No	No	9	8
148	2x56	3x31	rhodopsin_off	3.51333	0	No	No	Yes	No	6	4
149	3x52	I2x56	rhodopsin_off	3.49667	0	No	No	Yes	No	4	7
150	1x43	2x57	rhodopsin_off	3.35	0	No	No	Yes	Yes	6	7
151	8x54	8x58	rhodopsin_off	3.29667	0	Yes	No	No	No	6	6
152	3x30	4x57	rhodopsin_off	3.23333	0	Yes	Yes	No	No	6	7
153	CT.S343	CT.V337	rhodopsin_off	3.23333	0	No	No	No	No	9	5
154	8x48	CT.D330	rhodopsin_off	3.22667	0	Yes	No	No	No	4	5
155	2x59	3x24	rhodopsin_off	3.03333	0	No	No	No	No	5	5
156	CT.T335	I1x49	rhodopsin_off	3.00333	0	No	No	No	No	5	5
157	5x40	E2.Y191	rhodopsin_off	2.94333	0	No	No	Yes	Yes	4	6
158	7x32	7x36	rhodopsin_off	2.94	0	No	No	No	No	1	5
159	4x55	5x461	rhodopsin_off	2.93	0	No	No	Yes	Yes	4	6
160	1x53	7x50	rhodopsin_off	2.91667	0	No	No	No	No	9	9
161	E3.G280	NT.Y10	rhodopsin_off	2.9	0	No	No	No	Yes	1	7
162	1x40	2x61	rhodopsin_off	2.84333	0	No	No	No	No	3	6
163	1x47	2x51	rhodopsin_off	2.84333	0	Yes	No	No	No	6	7
164	6x47	7x43	rhodopsin_off	2.81667	0	No	No	No	No	8	6
165	1x30	1x34	rhodopsin_off	2.71333	0	Yes	No	No	No	3	4
166	CT.C323	CT.K339	rhodopsin_off	2.69333	0	No	No	No	No	9	5
167	5x66	5x68	rhodopsin_off	2.67667	0	No	No	No	No	5	5
168	3x44	5x53	rhodopsin_off	2.67333	0	No	No	No	No	7	6
169	6x51	7x38	rhodopsin_off	2.67	0	Yes	Yes	No	No	6	5
170	4x50	4x54	rhodopsin_off	2.66	0	Yes	No	No	No	9	3
171	2x48	2x52	rhodopsin_off	2.62	0	No	No	No	No	6	6
172	1x57	8x50	rhodopsin_off	2.59333	0	No	No	Yes	Yes	7	8
173	CT.S343	I1x48	rhodopsin_off	2.55	0	No	No	No	No	9	6
174	7x51	7x55	rhodopsin_off	2.53333	0	No	No	No	No	7	6
175	CT.K339	CT.T340	rhodopsin_off	2.50333	0	No	No	No	No	5	9
176	5x35	5x38	rhodopsin_off	2.48333	0	No	No	No	No	3	4
177	1x46	2x54	rhodopsin_off	2.45333	0	No	No	No	No	8	6
178	5x59	5x62	rhodopsin_off	2.45333	0	No	No	No	No	3	5
179	5x48	5x52	rhodopsin_off	2.45	0	No	No	No	No	4	4
180	1x40	1x41	rhodopsin_off	2.43333	0	No	No	No	No	3	5
181	5x58	5x67	rhodopsin_off	2.24333	0	No	No	No	No	9	4
182	CT.N326	CT.P327	rhodopsin_off	2.17333	0	No	No	No	No	3	5
183	5x69	6x28	rhodopsin_off	2.14333	0	No	No	No	No	5	4
184	5x69	6x31	rhodopsin_off	2.14333	0	No	No	Yes	No	5	4
185	6x25	CT.S334	rhodopsin_off	2.13333	0	No	No	No	No	4	6
186	4x38	4x41	rhodopsin_off	2.12	0	No	No	Yes	No	6	5
187	6x52	Lig	rhodopsin_off	2.09333	0	No	No	Yes	Yes	7	0
188	5x45	5x48	rhodopsin_off	2.05	0	No	No	No	No	5	4
189	5x45	5x49	rhodopsin_off	2.04667	0	No	No	No	No	5	5
190	6x42	6x46	rhodopsin_off	1.96	0	No	No	No	No	5	5
191	4x43	4x44	rhodopsin_off	1.94667	0	No	No	No	No	3	2
192	NT.A26	NT.P27	rhodopsin_off	1.87	0	No	No	No	No	2	8
193	2x38	4x42	rhodopsin_off	1.87	0	Yes	No	No	No	6	7
194	3x39	6x44	rhodopsin_off	1.84667	0	No	No	Yes	Yes	9	9
195	5x69	6x35	rhodopsin_off	1.84333	0	No	No	No	No	5	7
196	4x63	E2.T198	rhodopsin_off	1.82	0	No	No	No	No	5	1
197	3x53	I2x55	rhodopsin_off	1.74333	0	No	No	No	No	8	4
198	7x40	7x43	rhodopsin_off	1.73	0	No	No	No	No	7	6
199	5x63	5x64	rhodopsin_off	1.73	0	No	No	No	No	3	6
200	CT.G329	CT.L328	rhodopsin_off	1.71	0	No	No	No	No	4	4
201	6x24	6x26	rhodopsin_off	1.68	0	No	No	No	No	3	5
202	6x46	7x40	rhodopsin_off	1.67333	0	No	No	No	No	5	7
203	CT.E341	CT.G324	rhodopsin_off	1.63667	0	Yes	No	No	No	5	3
204	CT.T335	CT.V345	rhodopsin_off	1.58667	0	No	No	No	No	5	8
205	3x48	3x52	rhodopsin_off	1.54	0	No	No	No	No	6	4
206	1x45	1x49	rhodopsin_off	1.42667	0	No	No	No	No	5	8
207	6x32	8x47	rhodopsin_off	1.31333	0	No	No	Yes	No	7	8
208	6x52	6x53	rhodopsin_off	1.3	0	No	No	No	No	7	5
209	5x37	E2.E196	rhodopsin_off	1.27	0	Yes	No	No	No	3	1
210	CT.A346	CT.P347	rhodopsin_off	1.24667	0	No	No	No	No	5	4
211	8x55	8x59	rhodopsin_off	1.14	0	No	No	No	No	3	4
212	5x70	5x71	rhodopsin_off	1.01333	0	No	No	No	No	4	2
213	5x72	CT.A333	rhodopsin_off	1.01	0	No	No	No	No	5	4
214	1x54	1x58	rhodopsin_off	0.993333	0	No	No	No	No	7	2
215	1x58	2x44	rhodopsin_off	0.993333	0	No	No	No	No	2	5
216	I2x52	I2x53	rhodopsin_off	0.993333	0	No	No	No	No	4	5
217	4x61	4x62	rhodopsin_off	0.993333	0	No	No	No	No	5	4
218	8x52	8x55	rhodopsin_off	0.986667	0	No	No	No	No	5	3
219	5x58	5x59	rhodopsin_off	0.966667	0	No	No	No	No	9	3
220	6x24	CT.A348	rhodopsin_off	0.596667	0	No	No	No	No	3	5
221	E3.G280	NT.M1	rhodopsin_off	0.583333	0	No	No	No	No	1	6
222	NT.G3	NT.N2	rhodopsin_off	0.566667	0	No	No	No	No	6	6
223	1x49	7x51	rhodopsin_off	0.513333	0	No	No	No	No	8	7
224	3x56	I2x52	rhodopsin_off	0.51	0	No	No	No	No	6	4
225	4x51	4x52	rhodopsin_off	0.506667	0	No	No	No	No	4	4
226	6x29	CT.E332	rhodopsin_off	0.503333	0	No	No	Yes	No	6	5
227	5x66	5x67	rhodopsin_off	0.45	0	No	No	No	No	5	4
228	1x30	1x33	rhodopsin_off	0.413333	0	Yes	No	No	No	3	2
229	NT.G3	NT.Y10	Shared	5.31	4.35	No	No	No	Yes	6	7
230	NT.T4	NT.V20	Shared	10.5767	1.59	No	No	Yes	Yes	6	6
231	NT.G6	NT.P7	Shared	4.06	4.06	No	No	No	No	6	6
232	NT.F9	NT.G6	Shared	9.03	9.03	No	Yes	No	No	7	6
233	NT.F24	NT.N8	Shared	10.07	4.83	Yes	No	No	No	5	4
234	NT.F9	NT.S22	Shared	7.93	9.25	No	Yes	Yes	No	7	5
235	NT.F9	NT.P23	Shared	13.0033	14.45	No	Yes	Yes	Yes	7	5
236	NT.V11	NT.V20	Shared	4.81	3.21	No	Yes	Yes	Yes	8	6
237	E2.Q184	NT.V11	Shared	5.25667	5.73	Yes	Yes	No	Yes	3	8
238	NT.F13	NT.L31	Shared	4.87	3.65	No	No	Yes	No	4	4
239	NT.G18	NT.N15	Shared	5.65667	3.39	No	No	No	No	3	7
240	NT.N15	NT.V20	Shared	11.3333	7.39	No	No	Yes	Yes	7	6
241	NT.V19	NT.Y30	Shared	9.67333	3.79	No	No	Yes	Yes	3	4
242	NT.V20	NT.Y30	Shared	9.25333	6.31	Yes	Yes	Yes	Yes	6	4
243	NT.A26	NT.R21	Shared	6.45	2.77	No	No	No	No	2	4
244	NT.E25	NT.S22	Shared	10.06	4.31	No	No	Yes	No	7	5
245	E2.P180	NT.P23	Shared	7.14	3.9	Yes	No	Yes	Yes	3	5
246	E2.Q184	NT.P23	Shared	11.5767	7.9	Yes	Yes	Yes	Yes	3	5
247	E2.P180	NT.F24	Shared	6.74333	5.78	Yes	No	Yes	No	3	5
248	NT.P27	NT.Y29	Shared	6.95	4.17	No	No	Yes	No	8	4
249	E1x49	NT.P27	Shared	8.81	8.34	No	No	No	No	4	8
250	NT.Q28	NT.Y30	Shared	9.39667	10.15	Yes	No	Yes	Yes	5	4
251	NT.L31	NT.Q28	Shared	5.76333	5.32	Yes	No	Yes	No	4	5
252	E2.Q184	NT.Q28	Shared	6.4	6.4	Yes	Yes	Yes	No	3	5
253	1x29	NT.Y29	Shared	6.95667	5.56	No	No	Yes	No	3	4
254	1x32	NT.Y29	Shared	9.62667	4.13	No	No	Yes	No	5	4
255	7x31	NT.L31	Shared	8.21	11.49	No	No	Yes	No	3	4
256	1x28	1x30	Shared	4.72333	8.72	No	No	Yes	No	3	3
257	1x28	1x31	Shared	5.52	6.37	No	No	No	No	3	2
258	1x30	1x31	Shared	13.87	13.14	Yes	No	No	No	3	2
259	1x32	E2.M183	Shared	5.80667	6.22	No	No	No	Yes	5	2
260	1x38	1x42	Shared	6.25333	14.07	No	No	No	No	4	7
261	1x39	2x57	Shared	6.22	4.98	Yes	No	Yes	Yes	7	7
262	1x39	2x60	Shared	9.03333	3.01	Yes	No	No	No	7	7
263	1x40	1x44	Shared	9.95333	6.22	No	No	No	No	3	5
264	1x42	2x57	Shared	4.46333	10.96	No	No	Yes	Yes	7	7
265	1x43	2x54	Shared	4.61	4.61	No	No	No	No	6	6
266	1x47	1x48	Shared	4.33	5.78	Yes	No	No	No	6	4
267	1x47	2x55	Shared	5.71667	5.36	Yes	No	No	No	6	4
268	1x49	7x50	Shared	4.51667	5.08	No	No	No	No	8	9
269	1x50	2x50	Shared	11.2167	6.73	No	No	No	No	9	9
270	1x50	7x50	Shared	6.52	6.52	No	No	No	No	9	9
271	1x55	1x59	Shared	9.39667	21.42	No	Yes	Yes	No	3	5
272	1x56	8x57	Shared	7.40333	4.76	No	No	No	No	7	5
273	1x57	2x44	Shared	8.84667	10.32	No	No	No	No	7	5
274	1x60	I1x50	Shared	4.71333	2.57	Yes	No	Yes	Yes	5	7
275	1x60	8x53	Shared	9.83	8.85	Yes	No	No	No	5	5
276	2x37	2x38	Shared	4.08333	5.25	No	No	Yes	No	7	6
277	2x37	2x40	Shared	8.77333	8.77	No	No	No	No	7	8
278	2x41	4x39	Shared	11.9733	13.47	Yes	No	No	No	5	2
279	2x41	4x42	Shared	7.11667	2.67	Yes	No	No	No	5	7
280	2x42	3x45	Shared	4.60667	3.07	No	Yes	No	No	7	7
281	2x42	3x46	Shared	7.61	4.28	No	Yes	No	No	7	9
282	2x45	4x46	Shared	10.8367	11.82	No	Yes	No	No	9	7
283	2x45	4x49	Shared	6.33667	7.31	No	Yes	No	No	9	7
284	2x45	4x50	Shared	7.91	4.52	No	Yes	Yes	No	9	9
285	2x46	3x42	Shared	5.50333	6.01	No	No	No	No	9	8
286	2x49	3x38	Shared	5.41333	3.25	No	No	No	Yes	8	7
287	2x52	4x50	Shared	5.68	4.01	No	No	Yes	No	6	9
288	2x53	7x46	Shared	4.29333	4.83	No	No	No	No	7	9
289	2x57	7x42	Shared	8.27	9.93	Yes	Yes	Yes	No	7	7
290	2x61	2x65	Shared	4.61333	2.77	No	No	No	No	6	4
291	2x62	2x66	Shared	14.5167	3.27	No	No	No	No	4	4
292	2x63	E1x50	Shared	15.9933	10.38	No	No	No	Yes	5	8
293	2x64	E2.C185	Shared	4.58667	3.44	No	No	No	No	5	5
294	E1x49	E1x51	Shared	8.83333	7.57	No	No	Yes	No	4	4
295	E1x50	E2x50	Shared	7.91667	4.19	No	Yes	No	Yes	8	9
296	3x21	3x22	Shared	4.06	4.06	No	No	No	No	8	3
297	3x25	E2x50	Shared	7.28	7.28	No	No	No	Yes	9	9
298	3x26	E2.Y178	Shared	5.03667	8.14	No	No	Yes	Yes	7	3
299	3x29	E2.Y178	Shared	5.31	8.69	No	No	Yes	Yes	5	3
300	3x30	3x31	Shared	6.79	4.29	Yes	Yes	Yes	No	6	4
301	3x30	3x34	Shared	6.9	3.65	Yes	Yes	No	No	6	5
302	3x30	4x61	Shared	4.87333	6.09	Yes	Yes	No	No	6	5
303	3x32	Lig	Shared	6.04667	3.14	No	No	Yes	Yes	5	0
304	3x33	E2.Y178	Shared	5.82667	4.99	No	No	Yes	Yes	4	3
305	3x37	3x41	Shared	5.81333	7.63	Yes	Yes	Yes	Yes	6	5
306	3x37	5x461	Shared	7.39	11.08	Yes	Yes	Yes	Yes	6	6
307	3x37	Lig	Shared	5.41667	3.52	Yes	Yes	Yes	Yes	6	0
308	3x38	4x50	Shared	9.79	9.4	No	Yes	Yes	No	7	9
309	3x38	4x53	Shared	4.33	1.62	No	Yes	No	No	7	8
310	3x40	5x50	Shared	8.21	3.28	No	No	No	No	7	9
311	3x40	6x44	Shared	10.15	4.87	No	No	Yes	Yes	7	9
312	3x41	3x44	Shared	4.90333	4.9	Yes	Yes	No	No	5	7
313	3x41	4x48	Shared	4.34333	4.01	Yes	Yes	No	No	5	3
314	3x41	4x52	Shared	22.88	19.78	Yes	Yes	No	No	5	4
315	3x41	5x461	Shared	4.93667	8.46	Yes	Yes	Yes	Yes	5	6
316	3x44	5x54	Shared	4.09333	3.07	No	No	No	No	7	8
317	3x49	I2x56	Shared	10.4933	11.66	No	No	Yes	No	8	7
318	3x51	3x55	Shared	6.72	6.72	Yes	Yes	No	No	7	7
319	3x51	I2x50	Shared	8.80667	9.74	Yes	Yes	No	No	7	8
320	3x51	5x60	Shared	9.02	3.38	Yes	Yes	No	No	7	4
321	3x54	5x61	Shared	9.43667	4.47	No	No	No	No	8	8
322	I2x51	I2x54	Shared	5.80333	13.68	No	No	No	No	6	5
323	4x41	I2x54	Shared	10.1833	6.79	Yes	No	No	No	5	5
324	4x41	I2x56	Shared	7.54	5.66	Yes	No	Yes	No	5	7
325	4x40	4x41	Shared	9.77667	2.55	No	No	Yes	No	4	5
326	4x48	4x52	Shared	7.46333	7.46	No	No	No	No	3	4
327	4x56	5x461	Shared	13.2667	7.37	No	No	Yes	Yes	5	6
328	4x59	4x60	Shared	7.14	5.84	No	No	No	Yes	7	5
329	4x60	E2.Y178	Shared	11.5933	18.08	No	Yes	Yes	Yes	5	3
330	5x39	E2.W175	Shared	18.7067	12.03	Yes	Yes	No	Yes	6	5
331	5x42	E2.W175	Shared	9.96667	8.68	Yes	Yes	No	Yes	4	5
332	5x36	E2.S176	Shared	5.46333	2.98	Yes	Yes	No	No	4	5
333	5x39	E2.S176	Shared	11.01	13.21	Yes	Yes	No	No	6	5
334	E2.I179	E2.R177	Shared	5.42667	3.76	No	No	No	Yes	1	5
335	E2.D190	E2.R177	Shared	8.73333	5.96	Yes	Yes	No	Yes	4	5
336	E2.H195	E2.R177	Shared	21.0633	22.57	Yes	No	No	Yes	4	5
337	E2.Y178	E2x52	Shared	6.44667	4.84	Yes	Yes	No	Yes	3	4
338	E2.D190	E2.I179	Shared	8.86333	4.2	Yes	Yes	No	No	4	1
339	E2.P180	E2.Q184	Shared	8.42	3.16	Yes	No	Yes	Yes	3	3
340	E2.E181	E2x51	Shared	5.45667	6.55	Yes	Yes	No	No	4	5
341	E2.E181	E2.Y191	Shared	5.98333	10.1	Yes	Yes	Yes	Yes	4	6
342	E2.E181	E2.Y192	Shared	11.5967	4.49	Yes	Yes	Yes	Yes	4	5
343	7x35	E2.M183	Shared	11.5433	4.52	No	No	No	Yes	4	2
344	5x39	E2x52	Shared	4.18667	5.02	Yes	Yes	No	Yes	6	4
345	E2.D190	E2.T193	Shared	9.63333	13.01	Yes	Yes	No	Yes	4	5
346	5x36	E2.D190	Shared	13.4633	12.12	Yes	Yes	Yes	Yes	4	4
347	E2.Y191	E2.Y192	Shared	5.62667	10.92	Yes	Yes	Yes	Yes	6	5
348	6x51	E2.Y191	Shared	6.95	3.97	Yes	Yes	Yes	Yes	6	6
349	6x55	E2.Y191	Shared	8.89667	1.33	No	No	Yes	Yes	5	6
350	6x58	E2.Y192	Shared	10.88	2.42	No	No	Yes	Yes	4	5
351	E2.E197	E2.H195	Shared	16.0033	6.15	No	No	Yes	No	3	4
352	E2.H195	E2.T198	Shared	7.3	6.85	Yes	No	No	No	4	1
353	5x37	6x59	Shared	7.38333	4.66	Yes	No	No	No	3	4
354	5x39	5x42	Shared	7.22333	4.13	Yes	Yes	Yes	Yes	6	4
355	5x42	5x46	Shared	5.04667	6.31	Yes	Yes	No	No	4	4
356	5x42	5x461	Shared	11.6133	4.36	Yes	Yes	Yes	Yes	4	6
357	5x46	5x461	Shared	11.0733	4.15	No	No	Yes	Yes	4	6
358	5x47	5x51	Shared	4.87333	2.44	No	Yes	No	Yes	8	7
359	5x49	5x50	Shared	5.64333	3.39	No	No	No	No	5	9
360	5x56	5x60	Shared	8.97667	4.68	No	No	No	No	4	4
361	6x36	7x56	Shared	5.77333	7.22	No	No	No	No	8	7
362	6x39	7x52	Shared	4.90667	4.42	No	No	No	No	5	8
363	6x43	7x48	Shared	5.33667	5.34	No	No	No	Yes	7	5
364	6x44	6x48	Shared	16.37	9.02	Yes	Yes	Yes	Yes	9	8
365	6x45	6x49	Shared	7.38	5.54	No	No	No	No	6	6
366	6x48	Lig	Shared	14.0967	3.79	Yes	Yes	Yes	Yes	8	0
367	6x50	7x40	Shared	4.33333	4.33	No	No	No	No	9	7
368	6x51	Lig	Shared	21.77	20.27	Yes	Yes	Yes	Yes	6	0
369	6x56	6x60	Shared	8.21333	6.49	No	No	No	No	6	5
370	6x57	6x61	Shared	23.23	29.4	No	No	No	No	4	3
371	6x58	E3.F283	Shared	8.37333	5.02	No	No	No	Yes	4	4
372	6x60	6x61	Shared	7.75667	2.74	No	No	No	No	5	3
373	7x33	E3.F283	Shared	6.43	16.08	No	No	No	Yes	4	4
374	7x30	7x31	Shared	4.06	4.06	No	No	No	No	4	3
375	7x42	Lig	Shared	8.74333	10.31	Yes	No	Yes	Yes	7	0
376	7x36	7x37	Shared	3.95333	3.39	No	No	No	No	5	6
377	1x36	2x65	Shared	3.67667	3.15	No	No	No	No	5	4
378	1x28	1x29	Shared	3.66667	4.72	No	No	No	No	3	3
379	1x50	2x51	Shared	3.66333	4.12	No	No	No	No	9	7
380	5x51	5x55	Shared	3.65333	10.96	No	Yes	No	No	7	5
381	1x56	8x54	Shared	3.54667	3.04	No	No	Yes	No	7	6
382	6x47	6x48	Shared	3.48333	6.53	No	No	Yes	Yes	8	8
383	1x53	8x50	Shared	3.46	5.19	No	No	Yes	Yes	9	8
384	1x53	2x47	Shared	3.36	1.68	No	No	No	No	9	9
385	NT.T17	NT.V19	Shared	3.17333	4.76	No	No	No	No	6	3
386	3x55	5x61	Shared	3.17	3.17	No	No	No	No	7	8
387	1x31	NT.A32	Shared	3.03	3.03	No	No	No	No	2	3
388	1x35	E2.M183	Shared	2.83	2.83	No	No	No	Yes	5	2
389	3x51	5x57	Shared	2.68667	6.72	Yes	Yes	No	No	7	8
390	5x41	6x59	Shared	2.51	5.02	No	No	No	No	5	4
391	1x46	7x47	Shared	2.45333	3.68	No	No	No	No	8	7
392	6x23	6x26	Shared	2.13333	7.99	No	No	No	No	4	5
393	3x27	3x31	Shared	2.03333	4.87	No	No	Yes	No	4	4
394	4x58	4x59	Shared	1.87	1.87	No	No	No	No	3	7
395	5x51	6x45	Shared	1.84333	4.15	No	Yes	No	No	7	6
396	3x23	3x24	Shared	1.82	1.82	No	No	No	No	1	5
397	NT.K16	NT.S14	Shared	1.53	9.18	No	No	No	No	7	4
398	3x56	I2x50	Shared	1.11333	1.67	No	No	No	No	6	8
399	2x58	2x59	Shared	1.04667	3.14	No	No	No	No	8	5
400	NT.N2	NT.Y10	rhodopsin_on	0	4.65	No	No	No	Yes	6	7
401	NT.E5	NT.Y10	rhodopsin_on	0	6.73	No	No	No	Yes	6	7
402	NT.N8	NT.P7	rhodopsin_on	0	8.15	No	No	No	No	4	6
403	NT.F9	NT.P7	rhodopsin_on	0	5.78	No	Yes	No	No	7	6
404	3x22	NT.N8	rhodopsin_on	0	3.26	No	No	No	No	3	4
405	E2.T193	NT.Y10	rhodopsin_on	0	7.49	No	Yes	No	Yes	5	7
406	E2.P194	NT.Y10	rhodopsin_on	0	9.74	No	No	No	Yes	1	7
407	NT.P23	NT.V11	rhodopsin_on	0	3.53	Yes	Yes	No	Yes	5	8
408	NT.R21	NT.Y30	rhodopsin_on	0	5.14	No	No	Yes	Yes	4	4
409	E1x50	NT.F24	rhodopsin_on	0	3.22	No	Yes	Yes	No	8	5
410	E2.M183	NT.A32	rhodopsin_on	0	3.22	No	Yes	No	No	2	3
411	1x36	2x64	rhodopsin_on	0	3.42	No	No	No	No	5	5
412	1x38	7x39	rhodopsin_on	0	21.66	No	No	Yes	No	4	5
413	1x38	7x43	rhodopsin_on	0	6.24	No	No	No	No	4	6
414	1x39	7x42	rhodopsin_on	0	4.32	Yes	No	Yes	No	7	7
415	1x42	7x47	rhodopsin_on	0	2.98	No	No	No	No	7	7
416	1x45	7x47	rhodopsin_on	0	4.47	No	No	No	No	5	7
417	1x49	7x55	rhodopsin_on	0	2.92	No	No	No	No	8	6
418	1x52	1x55	rhodopsin_on	0	3.52	No	No	No	Yes	6	3
419	1x53	7x54	rhodopsin_on	0	4.56	No	No	No	Yes	9	7
420	1x56	I1x50	rhodopsin_on	0	2.98	No	No	Yes	Yes	7	7
421	1x57	I1x50	rhodopsin_on	0	7.37	No	No	Yes	Yes	7	7
422	1x60	I1x49	rhodopsin_on	0	6.55	Yes	No	No	No	5	5
423	8x53	I1x49	rhodopsin_on	0	3.23	No	No	No	No	5	5
424	8x50	I1x50	rhodopsin_on	0	12.18	Yes	Yes	Yes	Yes	8	7
425	2x40	8x50	rhodopsin_on	0	9.67	No	No	Yes	Yes	8	8
426	2x42	3x49	rhodopsin_on	0	10.93	No	Yes	No	No	7	8
427	2x45	3x38	rhodopsin_on	0	4.25	No	Yes	No	Yes	9	7
428	2x46	2x50	rhodopsin_on	0	5.43	No	No	No	No	9	9
429	2x46	3x43	rhodopsin_on	0	4.15	No	No	No	No	9	8
430	2x50	7x46	rhodopsin_on	0	4.63	No	No	No	No	9	9
431	2x53	3x36	rhodopsin_on	0	3.49	No	No	No	No	7	7
432	2x54	2x57	rhodopsin_on	0	6.55	No	No	Yes	Yes	6	7
433	2x56	3x28	rhodopsin_on	0	4.91	No	No	No	No	6	5
434	2x59	3x28	rhodopsin_on	0	11.29	No	No	No	No	5	5
435	2x60	E2.S186	rhodopsin_on	0	3.2	No	No	No	No	7	5
436	2x63	E2.C185	rhodopsin_on	0	5.07	No	No	No	No	5	5
437	E1x50	E1x52	rhodopsin_on	0	8.57	No	Yes	No	No	8	7
438	3x25	E1x50	rhodopsin_on	0	8.38	No	No	No	Yes	9	8
439	3x24	E1x52	rhodopsin_on	0	3.01	No	No	No	No	5	7
440	3x28	E2x50	rhodopsin_on	0	6.08	No	No	No	Yes	5	9
441	3x30	E2.Y178	rhodopsin_on	0	4.13	Yes	Yes	Yes	Yes	6	3
442	3x33	4x57	rhodopsin_on	0	3.36	No	No	No	No	4	7
443	3x33	E2x52	rhodopsin_on	0	4.56	No	No	No	Yes	4	4
444	3x34	3x38	rhodopsin_on	0	4.28	No	No	No	Yes	5	7
445	3x37	4x56	rhodopsin_on	0	12.15	Yes	Yes	No	No	6	5
446	3x38	4x49	rhodopsin_on	0	3.04	No	Yes	No	No	7	7
447	3x40	6x48	rhodopsin_on	0	20.5	No	No	Yes	Yes	7	8
448	3x43	7x49	rhodopsin_on	0	4.12	No	No	No	No	8	9
449	3x43	7x53	rhodopsin_on	0	16.41	No	No	Yes	Yes	8	9
450	3x45	4x49	rhodopsin_on	0	3.17	No	No	No	No	7	7
451	3x46	3x50	rhodopsin_on	0	6.07	No	No	Yes	No	9	9
452	3x46	7x53	rhodopsin_on	0	5.86	No	No	Yes	Yes	9	9
453	3x48	5x53	rhodopsin_on	0	3.07	No	No	No	No	6	6
454	3x48	5x57	rhodopsin_on	0	3.27	No	No	No	No	6	8
455	3x50	6x40	rhodopsin_on	0	3.72	Yes	No	No	Yes	9	8
456	3x51	5x56	rhodopsin_on	0	4.13	Yes	Yes	No	No	7	4
457	3x52	I2x50	rhodopsin_on	0	7.07	No	No	No	No	4	8
458	3x52	I2x51	rhodopsin_on	0	4.56	No	No	No	No	4	6
459	3x55	5x64	rhodopsin_on	0	3.38	No	No	No	No	7	6
460	4x56	5x43	rhodopsin_on	0	3.24	No	No	No	Yes	5	5
461	4x59	E2.W175	rhodopsin_on	0	5.4	No	No	No	Yes	7	5
462	4x60	E2.S176	rhodopsin_on	0	3.56	No	Yes	No	No	5	5
463	4x60	E2x52	rhodopsin_on	0	5.08	No	Yes	No	Yes	5	4
464	4x61	E2.Y178	rhodopsin_on	0	3.52	No	No	Yes	Yes	5	3
465	E2.R177	E2.T193	rhodopsin_on	0	3.88	No	Yes	No	Yes	5	5
466	E2.I179	E2.Y192	rhodopsin_on	0	6.04	No	No	Yes	Yes	1	5
467	E2.E181	E2.G182	rhodopsin_on	0	3.27	Yes	Yes	No	No	4	3
468	5x43	E2x52	rhodopsin_on	0	2.92	No	Yes	No	Yes	5	4
469	E2x52	Lig	rhodopsin_on	0	3.8	No	Yes	Yes	Yes	4	0
470	6x54	E2.Y191	rhodopsin_on	0	5.05	No	No	Yes	Yes	5	6
471	5x36	E2.T193	rhodopsin_on	0	4.39	Yes	Yes	No	Yes	4	5
472	5x39	5x43	rhodopsin_on	0	12.44	Yes	Yes	No	Yes	6	5
473	5x42	5x43	rhodopsin_on	0	3.59	Yes	Yes	No	Yes	4	5
474	5x43	5x461	rhodopsin_on	0	3.94	No	Yes	Yes	Yes	5	6
475	5x43	Lig	rhodopsin_on	0	8.46	No	Yes	Yes	Yes	5	0
476	5x44	5x47	rhodopsin_on	0	4.29	No	No	No	Yes	5	8
477	5x44	5x48	rhodopsin_on	0	3.77	No	No	No	No	5	4
478	5x47	5x48	rhodopsin_on	0	3.77	No	Yes	No	No	8	4
479	5x47	6x52	rhodopsin_on	0	8.32	No	Yes	No	No	8	7
480	5x54	6x44	rhodopsin_on	0	7.54	No	No	Yes	Yes	8	9
481	5x55	6x45	rhodopsin_on	0	3.65	No	No	No	No	5	6
482	5x58	6x37	rhodopsin_on	0	7.57	No	No	No	No	9	8
483	5x58	6x40	rhodopsin_on	0	10.78	No	No	No	Yes	9	8
484	5x62	6x37	rhodopsin_on	0	4.81	No	No	No	No	5	8
485	5x65	6x33	rhodopsin_on	0	4.81	No	No	No	No	8	8
486	5x67	5x71	rhodopsin_on	0	3.82	No	No	No	No	4	2
487	5x69	6x30	rhodopsin_on	0	3.02	No	No	No	No	5	7
488	6x30	6x31	rhodopsin_on	0	10.8	No	No	Yes	No	7	4
489	6x32	6x35	rhodopsin_on	0	8.14	No	No	No	No	7	7
490	6x35	6x39	rhodopsin_on	0	5.01	No	No	No	No	7	5
491	6x40	7x52	rhodopsin_on	0	2.92	No	Yes	No	No	8	8
492	6x40	7x53	rhodopsin_on	0	15.57	No	Yes	Yes	Yes	8	9
493	6x47	7x45	rhodopsin_on	0	5.16	No	No	No	No	8	9
494	6x47	7x48	rhodopsin_on	0	6.72	No	No	No	Yes	8	5
495	6x48	6x51	rhodopsin_on	0	3.86	Yes	Yes	Yes	Yes	8	6
496	6x51	7x37	rhodopsin_on	0	8.34	Yes	Yes	No	No	6	6
497	6x51	7x41	rhodopsin_on	0	5.34	Yes	Yes	No	No	6	8
498	6x57	E3.F283	rhodopsin_on	0	4.13	No	No	No	Yes	4	4
499	6x58	7x34	rhodopsin_on	0	2.92	No	No	Yes	No	4	4
500	E3.F283	E3.S281	rhodopsin_on	0	7.93	No	Yes	No	No	4	4
501	7x34	E3.F283	rhodopsin_on	0	3.73	Yes	No	No	Yes	4	4
502	7x39	7x40	rhodopsin_on	0	4.29	Yes	No	No	No	5	7
503	7x43	7x48	rhodopsin_on	0	4.99	No	No	No	Yes	6	5
504	7x45	7x48	rhodopsin_on	0	3.82	No	No	No	Yes	9	5
505	7x45	7x49	rhodopsin_on	0	7.45	No	No	No	No	9	9
506	7x49	7x53	rhodopsin_on	0	5.81	No	No	Yes	Yes	9	9
507	7x50	7x54	rhodopsin_on	0	5.08	No	No	No	Yes	9	7
508	7x52	7x53	rhodopsin_on	0	3.63	No	No	Yes	Yes	8	9
509	7x54	8x50	rhodopsin_on	0	7.54	No	Yes	Yes	Yes	7	8
510	8x47	8x50	rhodopsin_on	0	6.04	Yes	No	Yes	Yes	8	8
511	8x51	8x52	rhodopsin_on	0	3.62	No	No	No	No	8	5
512	8x51	CT.N326	rhodopsin_on	0	3.62	No	No	No	No	8	3
513	2x43	7x54	rhodopsin_on	0	2.85	No	No	No	Yes	8	7
514	1x32	E2.C185	rhodopsin_on	0	2.79	No	No	No	No	5	5
515	3x47	5x58	rhodopsin_on	0	2.67	No	No	No	No	9	9
516	2x39	3x49	rhodopsin_on	0	2.65	No	No	No	No	8	8
517	5x55	6x41	rhodopsin_on	0	2.62	No	No	No	No	5	8
518	1x55	8x57	rhodopsin_on	0	2.5	No	Yes	No	No	3	5
519	I1x48	I1x51	rhodopsin_on	0	2.48	No	No	No	No	6	6
520	2x51	2x55	rhodopsin_on	0	2.44	No	No	No	No	7	4
521	3x30	4x54	rhodopsin_on	0	2.44	Yes	Yes	No	No	6	3
522	5x51	6x44	rhodopsin_on	0	2.44	No	Yes	Yes	Yes	7	9
523	6x46	7x48	rhodopsin_on	0	2.42	No	No	No	Yes	5	5
524	5x60	5x63	rhodopsin_on	0	2.34	No	No	No	No	4	3
525	5x35	E2.W175	rhodopsin_on	0	2.26	No	No	No	Yes	3	5
526	2x551	2x56	rhodopsin_on	0	2.11	No	No	No	No	4	6
527	3x35	3x36	rhodopsin_on	0	2.11	No	No	No	No	8	7
528	1x51	1x55	rhodopsin_on	0	2.06	No	No	No	Yes	4	3
529	2x38	4x38	rhodopsin_on	0	2.03	Yes	No	No	No	6	6
530	3x29	E2x50	rhodopsin_on	0	1.96	No	No	No	Yes	5	9
531	3x36	3x39	rhodopsin_on	0	1.95	No	No	No	No	7	9
532	NT.P12	NT.V11	rhodopsin_on	0	1.77	No	No	No	Yes	8	8
533	2x42	4x45	rhodopsin_on	0	1.76	No	Yes	No	No	7	6
534	5x69	6x26	rhodopsin_on	0	1.68	No	No	No	No	5	5
535	7x35	7x38	rhodopsin_on	0	1.68	No	No	No	No	4	5
536	3x53	3x54	rhodopsin_on	0	1.6	No	No	No	No	8	8
537	5x45	5x46	rhodopsin_on	0	1.6	No	No	No	No	5	4
538	6x33	6x37	rhodopsin_on	0	1.6	No	No	No	No	8	8
539	NT.T4	NT.V11	rhodopsin_on	0	1.59	No	No	No	Yes	6	8
540	6x33	6x34	rhodopsin_on	0	1.59	No	No	No	No	8	6
541	1x54	2x47	rhodopsin_on	0	1.58	No	No	No	No	7	9
542	2x38	4x39	rhodopsin_on	0	1.57	Yes	No	No	No	6	2
543	8x56	8x57	rhodopsin_on	0	1.57	No	No	No	No	4	5
544	5x69	6x27	rhodopsin_on	0	1.52	No	No	No	No	5	4
545	7x32	7x35	rhodopsin_on	0	1.52	No	No	No	No	1	4
546	2x45	2x48	rhodopsin_on	0	1.48	No	Yes	No	No	9	6
547	5x36	5x40	rhodopsin_on	0	1.48	Yes	Yes	No	No	4	4
548	5x72	6x23	rhodopsin_on	0	1.44	No	No	No	No	5	4
549	6x36	6x40	rhodopsin_on	0	1.44	No	No	No	Yes	8	8
550	1x58	1x59	rhodopsin_on	0	1.43	No	No	Yes	No	2	5
551	5x65	6x30	rhodopsin_on	0	1.43	No	No	No	No	8	7
552	1x41	1x45	rhodopsin_on	0	1.38	No	No	No	No	5	5
553	4x39	4x43	rhodopsin_on	0	1.37	No	No	No	No	2	3
554	4x55	5x42	rhodopsin_on	0	1.33	No	No	Yes	Yes	4	4
555	2x40	8x49	rhodopsin_on	0	1.32	No	No	Yes	No	8	6
556	4x48	4x51	rhodopsin_on	0	1.31	No	No	No	No	3	4
557	1x57	I1x51	rhodopsin_on	0	1.29	No	No	No	No	7	6
558	1x40	1x43	rhodopsin_on	0	1.26	No	No	No	No	3	6
559	5x63	5x67	rhodopsin_on	0	1.17	No	No	No	No	3	4

Orange: nodes, hubs and links specific of rhodopsin_off network

Green: nodes, hubs and links shared by both networks

Purple: nodes, hubs and links specific of rhodopsin_on network

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Owner: the name of the network the hub belong to or "Shared" if the corresponding hub is present in both networks.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub in the corresponding network.

Num Of Links: the number of links of the corresponding hub in the corresponding network.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Owner	rhodopsin_off Avg Int. Strength	rhodopsin_on Avg Int. Strength	rhodopsin_off Num Of Links	rhodopsin_on Num Of Links	ConSurf
1	NT.S22	rhodopsin_off	6.63583	6.78	4	2	5
2	NT.F24	rhodopsin_off	7.15389	4.61	6	3	5
3	NT.Q28	rhodopsin_off	6.54133	7.29	5	3	5
4	NT.Y29	rhodopsin_off	6.97083	4.62	4	3	4
5	NT.L31	rhodopsin_off	6.56667	6.82	4	3	4
6	1x30	rhodopsin_off	5.43	10.93	4	2	3
7	1x39	rhodopsin_off	6.22167	4.10333	4	3	7
8	1x47	rhodopsin_off	4.5625	5.57	4	2	6
9	1x59	rhodopsin_off	8.77083	11.425	4	2	5
10	1x60	rhodopsin_off	7.09555	5.99	6	3	5
11	2x38	rhodopsin_off	5.19	2.95	4	3	6
12	2x41	rhodopsin_off	7.81667	8.07	4	2	5
13	E1x51	rhodopsin_off	7.25167	7.57	4	1	4
14	3x31	rhodopsin_off	5.232	4.58	5	2	4
15	3x50	rhodopsin_off	7.94722	4.895	6	2	9
16	I2x56	rhodopsin_off	6.465	8.66	4	2	7
17	4x41	rhodopsin_off	7.405	5	4	3	5
18	4x50	rhodopsin_off	6.51	5.97667	4	3	9
19	E2.P180	rhodopsin_off	6.04	4.28	6	3	3
20	E2.H195	rhodopsin_off	12.58	11.8567	4	3	4
21	5x37	rhodopsin_off	6.17833	4.66	4	1	3
22	I3.E239	rhodopsin_off	8.20667	0	4	0	2
23	6x31	rhodopsin_off	6.032	10.8	5	1	4
24	7x34	rhodopsin_off	7.1225	3.325	4	2	4
25	7x39	rhodopsin_off	8.91	12.975	4	2	5
26	7x42	rhodopsin_off	8.66583	8.18667	4	3	7
27	8x47	rhodopsin_off	3.6225	6.04	4	1	8
28	8x48	rhodopsin_off	4.3575	0	4	0	4
29	8x49	rhodopsin_off	5.505	1.32	4	1	6
30	8x54	rhodopsin_off	4.58583	3.04	4	1	6
31	CT.E332	rhodopsin_off	4.64583	0	4	0	5
32	CT.E341	rhodopsin_off	6.86667	0	5	0	5
33	CT.T342	rhodopsin_off	5.01417	0	4	0	6
34	NT.V20	Shared	8.99333	4.625	4	4	6
35	NT.P23	Shared	8.544	7.445	5	4	5
36	NT.Y30	Shared	8.318	6.3475	5	4	4
37	I1x50	Shared	6.395	6.275	4	4	7
38	2x57	Shared	5.20733	8.105	5	4	7
39	3x30	Shared	5.44917	4.12	4	5	6
40	3x37	Shared	6.3125	8.595	4	4	6
41	3x41	Shared	9.32278	8.956	6	5	5
42	3x51	Shared	6.80833	6.138	4	5	7
43	E2.Y178	Shared	6.84267	7.48429	5	7	3
44	E2.E181	Shared	8.53733	6.1025	5	4	4
45	E2.Q184	Shared	7.27867	5.7975	5	4	3
46	E2.D190	Shared	10.1733	8.8225	4	4	4
47	E2.Y191	Shared	6.00667	6.274	6	5	6
48	E2.Y192	Shared	7.85778	5.9675	6	4	5
49	5x36	Shared	7.6825	5.2425	4	4	4
50	5x39	Shared	9.02111	9.366	6	5	6
51	5x42	Shared	8.4625	4.73333	4	6	4
52	5x461	Shared	8.535	6.56	6	6	6
53	6x44	Shared	8.2075	5.9675	4	4	9
54	6x48	Shared	8.89333	8.74	6	5	8
55	6x51	Shared	9.82	8.356	5	5	6
56	7x53	Shared	14.2317	9.456	4	5	9
57	8x50	Shared	10.1533	8.124	4	5	8
58	Lig	Shared	8.69074	7.61286	9	7	0
59	NT.F9	rhodopsin_on	9.98778	9.6275	3	4	7
60	NT.Y10	rhodopsin_on	6.37778	6.592	3	5	7
61	NT.V11	rhodopsin_on	4.78889	3.166	3	5	8
62	1x55	rhodopsin_on	9.39667	7.375	1	4	3
63	2x42	rhodopsin_on	5.79222	5.01	3	4	7
64	2x45	rhodopsin_on	8.36111	5.876	3	5	9
65	E1x50	rhodopsin_on	9.41444	6.948	3	5	8
66	3x38	rhodopsin_on	6.51111	4.30667	3	6	7
67	4x60	rhodopsin_on	8.49111	8.14	3	4	5
68	E2.W175	rhodopsin_on	11.2044	7.0925	3	4	5
69	E2.R177	rhodopsin_on	11.7411	9.0425	3	4	5
70	E2.M183	rhodopsin_on	6.72667	4.1975	3	4	2
71	E2x50	rhodopsin_on	6.94889	4.8775	3	4	9
72	E2x52	rhodopsin_on	5.42444	4.37	3	6	4
73	E2.T193	rhodopsin_on	10.2267	7.1925	2	4	5
74	5x43	rhodopsin_on	4.97333	5.765	1	6	5
75	5x47	rhodopsin_on	5.61333	4.705	2	4	8
76	5x51	rhodopsin_on	3.45667	4.9975	3	4	7
77	6x40	rhodopsin_on	5.165	6.886	2	5	8
78	E3.F283	rhodopsin_on	6.31111	7.378	3	5	4
79	7x48	rhodopsin_on	10.615	4.658	2	5	5
80	7x54	rhodopsin_on	6.31667	5.0075	1	4	7

Orange: nodes, hubs and links specific of rhodopsin_off network

Green: nodes, hubs and links shared by both networks

Purple: nodes, hubs and links specific of rhodopsin_on network

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Owner: the name of the network the link belong to or "Shared" if the corresponding link is present in both networks.

Recurrence: the relative Recurrence in the filtered pool of shortest paths.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Owner	rhodopsin_off Recurrence	rhodopsin_on Recurrence	rhodopsin_off Hub1?	rhodopsin_on Hub1?	rhodopsin_off Hub2?	rhodopsin_on Hub2?	ConSurf1	ConSurf2
1	E2.Y191	E2x52	rhodopsin_off	29.911	0	Yes	Yes	No	Yes	6	4
2	5x36	E2.D190	rhodopsin_off	69.6745	5.5116	Yes	Yes	Yes	Yes	4	4
3	E2.D190	E2.I179	rhodopsin_off	64.0957	5.66983	Yes	Yes	No	No	4	1
4	E2.I179	E2.P180	rhodopsin_off	63.1266	0	No	No	Yes	No	1	3
5	NT.P23	NT.Q28	rhodopsin_off	13.7445	0	Yes	Yes	Yes	No	5	5
6	NT.Q28	NT.Y30	rhodopsin_off	12.1267	7.61603	Yes	No	Yes	Yes	5	4
7	NT.L31	NT.Q28	rhodopsin_off	12.073	6.17616	Yes	No	Yes	No	4	5
8	7x39	7x42	rhodopsin_off	33.1178	0	Yes	No	Yes	No	5	7
9	1x35	7x39	rhodopsin_off	25.1017	0	No	No	Yes	No	5	5
10	1x35	E2.M183	rhodopsin_off	22.0791	1.59283	No	No	No	Yes	5	2
11	1x39	2x61	rhodopsin_off	18.2256	0	Yes	No	No	No	7	6
12	1x53	7x50	rhodopsin_off	10.4072	0	No	No	No	No	9	9
13	1x53	8x50	rhodopsin_off	12.0807	0.416667	No	No	Yes	Yes	9	8
14	7x53	8x50	rhodopsin_off	22.7431	0	Yes	Yes	Yes	Yes	9	8
15	2x43	7x53	rhodopsin_off	52.1225	0	No	No	Yes	Yes	8	9
16	2x43	6x40	rhodopsin_off	52.4756	0	No	No	No	Yes	8	8
17	6x40	7x49	rhodopsin_off	52.9093	0	No	Yes	No	No	8	9
18	2x46	7x49	rhodopsin_off	54.4408	0	No	No	No	No	9	9
19	2x46	3x42	rhodopsin_off	54.9896	1.78797	No	No	No	No	9	8
20	3x42	4x49	rhodopsin_off	93.69	0	No	No	No	No	8	7
21	2x45	4x49	rhodopsin_off	93.9971	3.37025	No	Yes	No	No	9	7
22	2x45	4x50	rhodopsin_off	94.5997	1.34494	No	Yes	Yes	No	9	9
23	2x52	4x50	rhodopsin_off	96.039	2.36814	No	No	Yes	No	6	9
24	2x52	3x31	rhodopsin_off	96.5879	0	No	No	Yes	No	6	4
25	3x30	3x31	rhodopsin_off	98.6298	3.89768	Yes	Yes	Yes	No	6	4
26	3x30	4x61	rhodopsin_off	99.3322	0.427215	Yes	Yes	No	No	6	5
27	3x26	4x61	rhodopsin_off	99.7812	0	No	No	No	No	7	5
28	3x26	E2.Y178	rhodopsin_off	100	1.5981	No	No	Yes	Yes	7	3
29	1x60	I1x50	rhodopsin_off	17.5405	5.33755	Yes	No	Yes	Yes	5	7
30	2x40	I1x50	rhodopsin_off	20.2099	0	No	No	Yes	Yes	8	7
31	2x40	7x53	rhodopsin_off	20.3404	0	No	No	Yes	Yes	8	9
32	8x47	8x49	rhodopsin_off	13.6563	0	Yes	No	Yes	No	8	6
33	7x53	8x47	rhodopsin_off	17.9205	0	Yes	Yes	Yes	No	9	8
34	1x60	CT.S338	rhodopsin_off	11.2747	0	Yes	No	No	No	5	9
35	2x38	3x49	rhodopsin_off	12.3302	0	Yes	No	No	No	6	8
36	3x49	3x50	rhodopsin_off	18.4578	0	No	No	Yes	No	8	9
37	3x50	6x37	rhodopsin_off	37.8157	0	Yes	No	No	No	9	8
38	3x46	6x37	rhodopsin_off	38.2072	0	No	No	No	No	9	8
39	2x42	3x42	rhodopsin_off	40.464	0	No	Yes	No	No	7	8
40	3x33	E2.Y178	rhodopsin_off	57.0814	1.4557	No	No	Yes	Yes	4	3
41	3x33	Lig	rhodopsin_off	56.7974	0	No	No	Yes	Yes	4	0
42	3x37	5x461	rhodopsin_off	11.7314	2.73207	Yes	Yes	Yes	Yes	6	6
43	5x42	5x461	rhodopsin_off	13.852	0.996835	Yes	Yes	Yes	Yes	4	6
44	5x39	5x42	rhodopsin_off	14.8327	3.66561	Yes	Yes	Yes	Yes	6	4
45	3x50	6x34	rhodopsin_off	30.1144	0	Yes	No	No	No	9	6
46	3x54	5x65	rhodopsin_off	12.0615	0	No	No	No	No	8	8
47	5x65	6x34	rhodopsin_off	29.3659	0	No	No	No	No	8	6
48	4x60	5x39	rhodopsin_off	30.9492	0	No	Yes	Yes	Yes	5	6
49	5x65	6x31	rhodopsin_off	17.6787	0	No	No	Yes	No	8	4
50	E2.Y191	E2.Y192	Shared	12.6468	26.1498	Yes	Yes	Yes	Yes	6	5
51	5x39	E2x52	Shared	44.8779	12.6319	Yes	Yes	No	Yes	6	4
52	5x39	E2.S176	Shared	79.4542	14.3671	Yes	Yes	No	No	6	5
53	5x36	E2.S176	Shared	78.107	29.9473	Yes	Yes	No	No	4	5
54	E2.P180	E2.Q184	Shared	23.8658	24.462	Yes	No	Yes	Yes	3	3
55	E2.P180	NT.P23	Shared	22.3651	14.3407	Yes	No	Yes	Yes	3	5
56	E2.P180	NT.F24	Shared	10.5243	40.0949	Yes	No	Yes	No	3	5
57	E2.Q184	NT.Q28	Shared	13.4874	14.8418	Yes	Yes	Yes	No	3	5
58	6x51	Lig	Shared	21.8872	16.0338	Yes	Yes	Yes	Yes	6	0
59	7x42	Lig	Shared	50.2629	23.1224	Yes	No	Yes	Yes	7	0
60	1x32	E2.M183	Shared	19.0662	12.384	No	No	No	Yes	5	2
61	1x32	NT.Y29	Shared	16.9782	10.8544	No	No	Yes	No	5	4
62	6x51	E2.Y191	Shared	15.7001	34.2194	Yes	Yes	Yes	Yes	6	6
63	2x57	7x42	Shared	17.3179	16.8302	Yes	Yes	Yes	No	7	7
64	E2.Y178	E2x52	Shared	46.8527	73.3386	Yes	Yes	No	Yes	3	4
65	2x42	3x46	Shared	38.6332	34.8523	No	Yes	No	No	7	9
66	6x48	Lig	Shared	12.8829	78.8977	Yes	Yes	Yes	Yes	8	0
67	3x37	Lig	Shared	22.3209	10.9863	Yes	Yes	Yes	Yes	6	0
68	4x60	E2.Y178	Shared	32.3367	14.7574	No	Yes	Yes	Yes	5	3
69	NT.F24	NT.N8	rhodopsin_on	1.56982	11.7458	Yes	No	No	No	5	4
70	E1x50	NT.F24	rhodopsin_on	0	52.2679	No	Yes	Yes	No	8	5
71	E1x50	E2x50	rhodopsin_on	0.00575727	80.0475	No	Yes	No	Yes	8	9
72	3x29	E2x50	rhodopsin_on	0	86.73	No	No	No	Yes	5	9
73	3x29	E2.Y178	rhodopsin_on	0.877025	87.5949	No	No	Yes	Yes	5	3
74	4x60	E2.S176	rhodopsin_on	0	18.2384	No	Yes	No	No	5	5
75	5x36	E2.T193	rhodopsin_on	0	19.3143	Yes	Yes	No	Yes	4	5
76	E2.T193	NT.Y10	rhodopsin_on	0	19.7838	No	Yes	No	Yes	5	7
77	2x63	E1x50	rhodopsin_on	1.55254	32.8323	No	No	No	Yes	5	8
78	2x63	E2.C185	rhodopsin_on	0	31.4504	No	No	No	No	5	5
79	1x32	E2.C185	rhodopsin_on	0	24.3829	No	No	No	No	5	5
80	1x42	2x57	rhodopsin_on	2.23958	12.1835	No	No	Yes	Yes	7	7
81	E2x52	Lig	rhodopsin_on	0	78.9135	No	Yes	Yes	Yes	4	0
82	5x43	Lig	rhodopsin_on	0	17.0992	No	Yes	Yes	Yes	5	0
83	7x43	7x48	rhodopsin_on	0	10.6118	No	No	No	Yes	6	5
84	6x47	6x48	rhodopsin_on	6.48077	96.097	No	No	Yes	Yes	8	8
85	6x48	6x51	rhodopsin_on	0	23.3597	Yes	Yes	Yes	Yes	8	6
86	E2.I179	E2.Y192	rhodopsin_on	0	13.2648	No	No	Yes	Yes	1	5
87	1x50	2x50	rhodopsin_on	0.88662	64.7521	No	No	No	No	9	9
88	2x46	2x50	rhodopsin_on	0	72.7584	No	No	No	No	9	9
89	2x46	3x43	rhodopsin_on	0	75.3428	No	No	No	No	9	8
90	3x43	7x49	rhodopsin_on	0	58.75	No	No	No	No	8	9
91	7x45	7x49	rhodopsin_on	0	100	No	No	No	No	9	9
92	6x47	7x45	rhodopsin_on	0	90.4061	No	No	No	No	8	9
93	1x50	7x50	rhodopsin_on	6.13725	57.7901	No	No	No	No	9	9
94	1x56	8x57	rhodopsin_on	5.04529	12.2468	No	No	No	No	7	5
95	1x56	I1x50	rhodopsin_on	0	15.6804	No	No	Yes	Yes	7	7
96	8x50	I1x50	rhodopsin_on	0	28.9768	Yes	Yes	Yes	Yes	8	7
97	7x54	8x50	rhodopsin_on	0	45.6593	No	Yes	Yes	Yes	7	8
98	7x50	7x54	rhodopsin_on	0	53.4863	No	No	No	Yes	9	7
99	2x37	2x40	rhodopsin_on	9.75282	12.3259	No	No	No	No	7	8
100	2x40	8x50	rhodopsin_on	0	15.6857	No	No	Yes	Yes	8	8
101	2x37	2x38	rhodopsin_on	9.72212	10.596	No	No	Yes	No	7	6
102	2x42	3x45	rhodopsin_on	1.8903	28.2595	No	Yes	No	No	7	7
103	3x45	4x49	rhodopsin_on	0	28.2911	No	No	No	No	7	7
104	3x38	4x49	rhodopsin_on	0	25.2584	No	Yes	No	No	7	7
105	3x34	3x38	rhodopsin_on	0	30.0422	No	No	No	Yes	5	7
106	3x30	3x34	rhodopsin_on	0.900054	30.385	Yes	Yes	No	No	6	5
107	3x30	E2.Y178	rhodopsin_on	0	32.3154	Yes	Yes	Yes	Yes	6	3
108	3x46	7x53	rhodopsin_on	0	31.693	No	No	Yes	Yes	9	9
109	7x49	7x53	rhodopsin_on	0	40.6751	No	No	Yes	Yes	9	9
110	2x42	3x49	rhodopsin_on	0	39.9789	No	Yes	No	No	7	8
111	6x44	6x48	rhodopsin_on	2.57734	18.6709	Yes	Yes	Yes	Yes	9	8
112	6x40	7x53	rhodopsin_on	0	29.0401	No	Yes	Yes	Yes	8	9
113	3x51	I2x50	rhodopsin_on	3.52153	24.0665	Yes	Yes	No	No	7	8
114	3x52	I2x50	rhodopsin_on	0	27.347	No	No	No	No	4	8
115	3x52	I2x51	rhodopsin_on	0	28.9715	No	No	No	No	4	6
116	I2x51	I2x54	rhodopsin_on	0.882782	30.5854	No	No	No	No	6	5
117	4x41	I2x54	rhodopsin_on	1.70415	32.1203	Yes	No	No	No	5	5
118	4x41	I2x56	rhodopsin_on	4.32371	35.3006	Yes	No	Yes	No	5	7
119	3x49	I2x56	rhodopsin_on	5.59991	36.8724	No	No	Yes	No	8	7
120	5x51	6x44	rhodopsin_on	0	15.3745	No	Yes	Yes	Yes	7	9
121	5x58	6x40	rhodopsin_on	0	26.9673	No	No	No	Yes	9	8
122	5x58	6x37	rhodopsin_on	0	23.27	No	No	No	No	9	8
123	5x65	6x33	rhodopsin_on	0	15.6857	No	No	No	No	8	8
124	6x33	6x37	rhodopsin_on	0	19.4568	No	No	No	No	8	8
125	5x65	6x30	rhodopsin_on	0	13.8291	No	No	No	No	8	7
126	6x58	E3.F283	rhodopsin_on	0.0230291	11.4399	No	No	No	Yes	4	4
127	6x58	E2.Y192	rhodopsin_on	1.1457	14.5675	No	No	Yes	Yes	4	5
128	7x45	7x48	rhodopsin_on	0	10.1582	No	No	No	Yes	9	5
129	3x43	7x53	rhodopsin_on	0	17.8534	No	No	Yes	Yes	8	9

Here, those paths that begin and end at given residue pair(s) or that pass through a residue are used to generate a novel metapath. Such a path filtering is particularly recommended if some information on allosteric residues is available. The selection syntax for a residue pair ("Pairs") is C:C:c534,A:A:?600 (the lower-case "c" stands for cytosine and "?" indicates any non standard amino acid or nucleotide residue). Selection of more than one apical residue pair has the following syntax: C:C:c534,A:A:?600,C:C:c534,A:A:E41. Only one residue can be selected as a tail ("Tail"). For midway residue(s), each residue must be separated by a comma as well e.g. A:A:?600,A:A:E41.

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Node1	Node2	Owner	Net1LinkStrength	Net2LinkStrength	Comm1	Comm2	Node1Shell	Node2Shell
1x39	2x57	Shared	6.22	4.98	0	1	2	2
1x39	2x60	Shared	9.03333	3.01	0	1	2	2
1x39	7x39	rhodopsin_off	5.39333	0	0	1	2	2
2x57	7x42	Shared	8.27	9.93	0	1	2	1
2x60	3x28	rhodopsin_off	11.29	0	0	0	2	1
3x28	7x42	rhodopsin_off	8.55	0	2	0	1	1
3x28	Lig	rhodopsin_off	4.91667	0	2	0	1	0
3x32	Lig	Shared	6.04667	3.14	0	0	1	0
3x33	E2.Y178	Shared	5.82667	4.99	0	1	1	2
3x33	Lig	rhodopsin_off	8.78	0	0	1	1	0
3x36	6x48	rhodopsin_off	4.69	0	0	0	2	1
3x37	3x40	rhodopsin_off	6.63	0	2	1	1	2
3x37	3x41	Shared	5.81333	7.63	2	1	1	2
3x37	5x461	Shared	7.39	11.08	2	1	1	2
3x37	Lig	Shared	5.41667	3.52	2	1	1	0
3x40	6x44	Shared	10.15	4.87	0	1	2	2
3x41	5x461	Shared	4.93667	8.46	2	1	2	2
4x56	5x461	Shared	13.2667	7.37	0	1	2	2
4x60	E2.Y178	Shared	11.5933	18.08	2	1	2	2
4x60	5x39	rhodopsin_off	6.74	0	2	1	2	2
E2.Y178	E2x52	Shared	6.44667	4.84	0	1	2	1
E2.E181	E2.Y191	Shared	5.98333	10.1	2	1	2	2
6x51	E2.E181	rhodopsin_off	9.72667	0	2	1	1	2
7x34	E2.E181	rhodopsin_off	9.92333	0	2	1	2	2
E2.Y191	E2x52	rhodopsin_off	5.64	0	2	1	2	1
5x39	E2x52	Shared	4.18667	5.02	2	1	2	1
6x51	E2.Y191	Shared	6.95	3.97	2	1	1	2
5x39	5x42	Shared	7.22333	4.13	2	1	2	2
5x42	5x461	Shared	11.6133	4.36	2	1	2	2
5x43	5x44	rhodopsin_off	4.97333	0	0	1	1	2
5x47	5x51	Shared	4.87333	2.44	0	1	1	2
5x47	Lig	rhodopsin_off	6.35333	0	0	1	1	0
6x44	6x48	Shared	16.37	9.02	0	1	2	1
6x48	7x41	rhodopsin_off	6.48333	0	0	1	1	2
6x48	7x45	rhodopsin_off	8.23667	0	0	1	1	2
6x48	Lig	Shared	14.0967	3.79	0	1	1	0
6x51	7x34	rhodopsin_off	7.98333	0	2	1	1	2
6x51	Lig	Shared	21.77	20.27	2	1	1	0
7x39	7x42	rhodopsin_off	9.1	0	0	0	2	1
7x42	Lig	Shared	8.74333	10.31	2	1	1	0
6x47	6x48	Shared	3.48333	6.53	0	1	2	1
6x51	7x38	rhodopsin_off	2.67	0	2	1	1	2
6x52	Lig	rhodopsin_off	2.09333	0	0	0	1	0
6x52	6x53	rhodopsin_off	1.3	0	0	0	1	2
1x39	7x42	rhodopsin_on	0	4.32	0	1	2	1
2x56	3x28	rhodopsin_on	0	4.91	0	0	2	1
2x59	3x28	rhodopsin_on	0	11.29	0	0	2	1
3x28	E2x50	rhodopsin_on	0	6.08	2	0	1	2
3x33	4x57	rhodopsin_on	0	3.36	0	1	1	2
3x33	E2x52	rhodopsin_on	0	4.56	0	1	1	1
3x37	4x56	rhodopsin_on	0	12.15	2	1	1	2
3x40	6x48	rhodopsin_on	0	20.5	0	1	2	1
4x56	5x43	rhodopsin_on	0	3.24	0	1	2	1
4x60	E2x52	rhodopsin_on	0	5.08	2	1	2	1
5x43	E2x52	rhodopsin_on	0	2.92	0	1	1	1
E2x52	Lig	rhodopsin_on	0	3.8	0	1	1	0
5x39	5x43	rhodopsin_on	0	12.44	2	1	2	1
5x42	5x43	rhodopsin_on	0	3.59	2	1	2	1
5x43	5x461	rhodopsin_on	0	3.94	0	1	1	2
5x43	Lig	rhodopsin_on	0	8.46	0	1	1	0
5x44	5x47	rhodopsin_on	0	4.29	0	1	2	1
5x44	5x48	rhodopsin_on	0	3.77	0	1	2	2
5x47	5x48	rhodopsin_on	0	3.77	0	1	1	2
5x47	6x52	rhodopsin_on	0	8.32	0	1	1	1
6x47	7x45	rhodopsin_on	0	5.16	0	1	2	2
6x48	6x51	rhodopsin_on	0	3.86	0	1	1	1
6x51	7x37	rhodopsin_on	0	8.34	2	1	1	2
6x51	7x41	rhodopsin_on	0	5.34	2	1	1	2
5x51	6x44	rhodopsin_on	0	2.44	0	1	2	2

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Difference Members
	Id	Description
	rhodopsin_off	1U19-Rhodopsin-11-cis-Retinal 2PED-Rhodopsin-9-cis-Retinal 5TE5-Rhodopsin-20-Methanoretinal
	rhodopsin_on	6OYA-Rhodopsin-All-trans-Retinal-Gt/β1/γ1

Network Difference
Value	rhodopsin_off	rhodopsin_on
I_min	3.98667	2.92
Number of Linked Nodes	347	288
Number of Specific Nodes	59 (17.00%)	0 (0.00%)
Number of Shared Nodes	288 (83.00%)	288 (100.00%)
Number of Links	399	331
Number of Specific Links	228 (57.14%)	160 (48.34%)
Number of Shared Links	171 (42.86%)	171 (51.66%)
Number of Hubs	58	47
Number of Specific Hubs	33 (56.90%)	22 (46.81%)
Number of Shared Hubs	25 (43.10%)	25 (53.19%)
Average % Shared Neighbours (Jaccard)	31.72
Average % Shared Neighbours (Otsuka)	40.13
Average % Shared Neighbours (Overlap Coefficient)	48.29
Average % Shared Cliques (k3-6)	78.03
Graphlets Similarity	0.65275

Paths Difference
Value	rhodopsin_off	rhodopsin_on
Number Of Nodes in MetaPath	66	77
Specific Nodes in MetaPath	27 (40.91%)	38 (49.35%)
Shared Nodes in MetaPath	288 (83.00%)	288 (83.00%)
Number Of Links MetaPath	68	80
Specific Links in MetaPath	49 (72.06%)	61 (76.25%)
Shared Links in MetaPath	171 (42.86%)	171 (42.86%)
Number of Shortest Paths	103239	50607
Length Of Smallest Path	3	3
Average Path Length	18.4548	13.9603
Length of Longest Path	37	30
Minimum Path Strength	0.751667	1.47
Average Path Strength	7.19037	6.10385
Maximum Path Strength	22.8433	17.865
Minimum Path Correlation	0.7	0.7
Average Path Correlation	0.937289	0.936249
Maximum Path Correlation	1	1
Minimum % Of Corr. Nodes	3.125	4.34783
Average % Of Corr. Nodes	47.1766	55.9685
Maximum % Of Corr. Nodes	100	100
Minimum Path Hubs %	0	0
Average Path Hubs %	44.4792	42.6517
Maximum Path Hubs %	100	100

Details about the values in these tables can be found in the corresponding documentation page .

You can download a compressed (zip) file with structure(s), 3D outputs (as PyMol and VMD scripts) and numerical data files (as csv and plain text files).

Download rhodopsin_off_on.zip<

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