psnGPCR

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Orange: nodes, hubs and links specific of sst_off network

Green: nodes, hubs and links shared by both networks

Purple: nodes, hubs and links specific of sst_on network

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Owner: the name of the network the link belong to or "Shared" if the corresponding link is present in both networks.

Strength: the interaction strength between the two nodes or 0 if the link is not present.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Owner	sst_off Int. Strength	sst_on Int. Strength	sst_off Hub1?	sst_on Hub1?	sst_off Hub2?	sst_on Hub2?	ConSurf1	ConSurf2
1	1x32	2x64	sst_off	4.43	0	Yes	Yes	Yes	No	3	4
2	1x32	E1	sst_off	10.52	0	Yes	Yes	No	No	3	4
3	1x32	Lig	sst_off	16.87	0	Yes	Yes	Yes	Yes	3	0
4	1x35	2x64	sst_off	4.47	0	No	Yes	Yes	No	5	4
5	1x37	1x41	sst_off	6.55	0	No	No	No	No	6	5
6	1x39	2x64	sst_off	5.05	0	Yes	Yes	Yes	No	7	4
7	1x39	7x42	sst_off	4.96	0	Yes	Yes	Yes	Yes	7	7
8	1x40	2x61	sst_off	6.93	0	No	No	No	No	5	6
9	1x46	2x54	sst_off	5.24	0	No	No	No	No	8	6
10	1x52	8x58	sst_off	8.3	0	No	No	No	No	6	7
11	1x54	2x44	sst_off	4.28	0	Yes	No	No	No	7	6
12	1x54	2x48	sst_off	5.89	0	Yes	No	No	No	7	7
13	1x56	8x53	sst_off	6.46	0	No	No	No	No	7	5
14	1x57	2x40	sst_off	4.25	0	No	No	Yes	Yes	7	8
15	1x60	8x56	sst_off	5.81	0	Yes	Yes	No	No	6	4
16	2x40	I1x50	sst_off	7.01	0	Yes	Yes	Yes	No	8	7
17	8x49	I1x50	sst_off	8.41	0	No	Yes	Yes	No	5	7
18	8x50	I1x50	sst_off	8.71	0	Yes	Yes	Yes	No	8	7
19	8x53	I1x50	sst_off	6.13	0	No	No	Yes	No	5	7
20	2x39	3x50	sst_off	6.47	0	No	No	Yes	No	8	9
21	2x39	6x33	sst_off	4.76	0	No	No	No	No	8	8
22	2x42	3x45	sst_off	10.09	0	Yes	Yes	No	No	7	7
23	2x43	3x46	sst_off	4.37	0	No	No	No	No	8	9
24	2x43	7x53	sst_off	13.3	0	No	No	Yes	Yes	8	9
25	2x44	2x45	sst_off	4.12	0	No	No	No	No	6	9
26	2x50	3x35	sst_off	5.45	0	Yes	Yes	No	No	9	7
27	2x50	7x49	sst_off	4.09	0	Yes	Yes	No	No	9	9
28	2x59	3x24	sst_off	7.54	0	No	No	No	No	5	6
29	2x60	3x28	sst_off	4.47	0	No	No	No	No	6	5
30	2x62	2x66	sst_off	5.65	0	No	No	No	No	5	5
31	2x64	Lig	sst_off	7.94	0	Yes	No	Yes	Yes	4	0
32	E1	Lig	sst_off	13.91	0	No	No	Yes	Yes	4	0
33	E1x51	E1x52	sst_off	11.56	0	No	No	Yes	Yes	4	6
34	3x29	E2x50	sst_off	4.86	0	No	No	No	No	5	9
35	3x34	3x38	sst_off	7.6	0	No	Yes	Yes	No	5	7
36	3x35	7x46	sst_off	5.96	0	No	No	No	No	7	8
37	3x36	6x52	sst_off	7.89	0	Yes	Yes	Yes	No	7	7
38	3x37	3x41	sst_off	4.29	0	Yes	Yes	No	No	6	6
39	3x37	5x461	sst_off	4.52	0	Yes	Yes	No	No	6	6
40	3x43	6x40	sst_off	5.96	0	No	No	No	Yes	9	8
41	3x44	5x54	sst_off	6.08	0	No	No	Yes	No	7	7
42	3x46	6x37	sst_off	7.61	0	No	No	No	No	9	8
43	3x49	3x50	sst_off	4.76	0	No	No	Yes	No	8	9
44	3x50	6x33	sst_off	3.92	0	Yes	No	No	No	9	8
45	3x50	6x34	sst_off	11.64	0	Yes	No	No	No	9	7
46	3x50	6x37	sst_off	3.92	0	Yes	No	No	No	9	8
47	3x51	3x56	sst_off	4.36	0	Yes	Yes	No	No	8	5
48	3x52	I2x53	sst_off	6.01	0	No	No	No	No	4	5
49	3x54	6x30	sst_off	5.7	0	No	No	Yes	Yes	8	6
50	I2x50	I2x51	sst_off	5.08	0	No	No	No	No	8	5
51	4x56	5x46	sst_off	4.47	0	Yes	No	No	No	4	4
52	4x57	4x62	sst_off	8.75	0	No	No	No	No	7	5
53	4x59	4x62	sst_off	4.24	0	No	No	No	No	4	5
54	4x60	5x42	sst_off	4.17	0	No	No	No	No	8	4
55	5x36	5x40	sst_off	6.04	0	No	No	No	No	4	5
56	5x36	6x58	sst_off	5.09	0	No	No	No	No	4	4
57	5x39	5x43	sst_off	7.78	0	No	Yes	No	No	7	4
58	5x44	6x56	sst_off	6.55	0	No	No	No	No	5	5
59	5x47	5x51	sst_off	7.31	0	No	No	No	No	8	6
60	5x49	5x50	sst_off	5.3	0	No	No	No	No	5	9
61	5x51	5x54	sst_off	4.28	0	No	No	Yes	No	6	7
62	5x51	6x45	sst_off	9.99	0	No	No	No	No	6	6
63	5x58	6x38	sst_off	7.63	0	No	Yes	No	No	9	4
64	5x59	5x60	sst_off	6.09	0	No	No	No	No	4	4
65	5x59	5x63	sst_off	4.28	0	No	No	No	No	4	3
66	5x65	6x26	sst_off	10.46	0	No	No	No	No	8	4
67	6x23	6x24	sst_off	4.89	0	No	No	No	No	3	2
68	6x30	6x34	sst_off	7.06	0	Yes	Yes	No	No	6	7
69	6x39	7x56	sst_off	7.14	0	No	No	No	No	6	6
70	6x43	7x52	sst_off	4.47	0	No	No	No	No	7	8
71	6x44	7x45	sst_off	4.83	0	Yes	No	Yes	No	9	9
72	6x48	6x51	sst_off	5.01	0	Yes	Yes	Yes	Yes	8	6
73	6x48	6x52	sst_off	8.68	0	Yes	Yes	Yes	No	8	7
74	6x51	6x52	sst_off	8.25	0	Yes	Yes	Yes	No	6	7
75	6x51	7x37	sst_off	3.93	0	Yes	Yes	No	No	6	7
76	6x54	7x33	sst_off	9.95	0	No	No	No	No	4	4
77	6x54	Lig	sst_off	9.5	0	No	No	Yes	Yes	4	0
78	6x61	Lig	sst_off	4.41	0	No	No	Yes	Yes	3	0
79	7x31	E3	sst_off	6.69	0	No	No	No	No	3	2
80	7x30	Lig	sst_off	5.4	0	No	No	Yes	Yes	4	0
81	7x31	Lig	sst_off	14.22	0	No	No	Yes	Yes	3	0
82	7x34	7x38	sst_off	7.87	0	No	No	No	No	4	6
83	7x35	Lig	sst_off	15.53	0	No	Yes	Yes	Yes	2	0
84	7x41	7x42	sst_off	4.99	0	No	No	Yes	Yes	7	7
85	7x53	8x50	sst_off	8.25	0	Yes	Yes	Yes	Yes	9	8
86	8x52	8x63	sst_off	5.75	0	No	No	No	No	5	3
87	8x55	8x63	sst_off	4.07	0	No	No	No	No	4	3
88	8x56	8x63	sst_off	9.79	0	No	No	No	No	4	3
89	1x60	8x53	sst_off	3.82	0	Yes	Yes	No	No	6	5
90	1x53	7x53	sst_off	3.79	0	No	No	Yes	Yes	9	9
91	1x55	8x57	sst_off	3.79	0	No	No	Yes	No	3	5
92	1x43	2x58	sst_off	3.77	0	No	No	No	No	6	8
93	1x31	Lig	sst_off	3.74	0	No	No	Yes	Yes	4	0
94	1x40	2x62	sst_off	3.73	0	No	No	No	No	5	5
95	3x43	6x44	sst_off	3.65	0	No	No	Yes	No	9	9
96	3x51	5x61	sst_off	3.63	0	Yes	Yes	No	No	8	9
97	6x36	7x53	sst_off	3.59	0	No	No	Yes	Yes	8	9
98	1x53	2x47	sst_off	3.39	0	No	No	No	No	9	9
99	1x30	1x33	sst_off	3.36	0	No	No	No	No	4	4
100	3x29	4x65	sst_off	3.22	0	No	No	No	No	5	4
101	1x36	2x64	sst_off	3.17	0	No	No	Yes	No	5	4
102	5x40	6x59	sst_off	3.07	0	No	No	No	No	5	4
103	5x34	E2	sst_off	3.02	0	No	No	Yes	Yes	1	3
104	4x46	4x47	sst_off	3.01	0	No	No	No	No	7	4
105	1x52	8x57	sst_off	2.98	0	No	No	Yes	No	6	5
106	8x57	8x58	sst_off	2.98	0	Yes	No	No	No	5	7
107	6x43	7x45	sst_off	2.96	0	No	No	Yes	No	7	9
108	3x48	5x53	sst_off	2.94	0	No	No	No	No	6	6
109	5x40	5x41	sst_off	2.94	0	No	No	No	No	5	5
110	5x41	5x45	sst_off	2.94	0	No	No	No	No	5	4
111	1x30	1x32	sst_off	2.92	0	No	No	Yes	Yes	4	3
112	1x47	2x54	sst_off	2.83	0	No	No	No	No	6	6
113	2x54	2x57	sst_off	2.83	0	No	No	No	Yes	6	7
114	4x55	4x59	sst_off	2.77	0	No	No	No	No	3	4
115	7x54	8x54	sst_off	2.77	0	No	No	No	No	7	6
116	2x46	7x49	sst_off	2.75	0	No	No	No	No	9	9
117	8x51	8x55	sst_off	2.71	0	No	No	No	No	8	4
118	6x27	6x30	sst_off	2.7	0	No	No	Yes	Yes	3	6
119	8x55	8x61	sst_off	2.66	0	No	No	No	No	4	4
120	2x53	3x31	sst_off	2.62	0	Yes	Yes	No	No	6	5
121	7x36	7x40	sst_off	2.44	0	No	No	No	No	5	7
122	4x41	I2x56	sst_off	2.43	0	No	No	No	No	5	3
123	2x52	4x50	sst_off	2.28	0	No	No	Yes	Yes	7	9
124	5x32	Lig	sst_off	2.25	0	No	No	Yes	Yes	2	0
125	2x56	2x58	sst_off	2.03	0	No	No	No	No	6	8
126	3x33	4x57	sst_off	1.76	0	No	No	No	No	4	7
127	3x33	4x61	sst_off	1.76	0	No	No	No	No	4	3
128	7x31	7x32	sst_off	1.74	0	No	No	No	No	3	1
129	3x42	4x49	sst_off	1.71	0	No	No	No	No	8	6
130	4x51	4x54	sst_off	1.71	0	No	No	No	No	4	3
131	2x38	4x39	sst_off	1.69	0	No	No	No	No	4	3
132	2x41	4x39	sst_off	1.69	0	No	No	No	No	5	3
133	3x38	3x42	sst_off	1.69	0	Yes	No	No	No	7	8
134	5x64	I2x50	sst_off	1.67	0	No	Yes	No	No	5	8
135	3x23	3x24	sst_off	1.62	0	No	No	No	No	1	6
136	4x52	4x56	sst_off	1.6	0	No	No	Yes	No	4	4
137	8x62	8x64	sst_off	1.6	0	No	No	No	No	2	1
138	7x48	7x52	sst_off	1.58	0	No	No	No	No	6	8
139	3x39	3x40	sst_off	1.55	0	No	No	No	No	9	8
140	4x41	4x45	sst_off	1.52	0	No	No	No	No	5	5
141	5x48	5x52	sst_off	1.47	0	No	No	No	No	4	4
142	4x43	4x47	sst_off	1.44	0	No	No	No	No	1	4
143	6x31	6x32	sst_off	1.44	0	No	No	No	No	5	7
144	8x47	8x48	sst_off	1.33	0	No	No	No	No	8	5
145	5x56	5x60	sst_off	1.22	0	No	No	No	No	5	4
146	1x35	1x39	Shared	8.21	3.02	No	Yes	Yes	Yes	5	7
147	1x35	7x35	Shared	6.79	4.25167	No	Yes	No	Yes	5	2
148	1x36	2x65	Shared	5.03	2.91333	No	No	No	No	5	5
149	1x39	2x61	Shared	4	3.55667	Yes	Yes	No	No	7	6
150	1x43	2x57	Shared	4.76	4.62	No	No	No	Yes	6	7
151	1x47	2x51	Shared	5.3	4.86	No	No	No	Yes	6	7
152	1x49	7x50	Shared	4.06	1.015	No	No	No	No	8	9
153	1x50	2x50	Shared	8.17	8.08	No	No	Yes	Yes	9	9
154	1x50	7x50	Shared	9.77	10.3167	No	No	No	No	9	9
155	1x51	2x51	Shared	8.47	3.52667	No	No	No	Yes	5	7
156	1x54	2x51	Shared	5.47	2.27833	Yes	No	No	Yes	7	7
157	1x55	1x59	Shared	16.46	4.67167	No	No	No	No	3	4
158	1x56	8x54	Shared	3.93	1.09167	No	No	No	No	7	6
159	1x57	8x50	Shared	5.02	4.395	No	No	Yes	Yes	7	8
160	1x58	2x44	Shared	4.15	2.30833	No	No	No	No	3	6
161	1x59	1x60	Shared	18.52	5.83167	No	No	Yes	Yes	4	6
162	8x49	I1x49	Shared	6.99	3.96333	No	Yes	No	No	5	5
163	2x37	2x40	Shared	13.16	4.14167	No	No	Yes	Yes	7	8
164	2x38	I2x57	Shared	6.26	4.80167	No	No	No	Yes	4	5
165	2x40	8x50	Shared	7.25	3.62167	Yes	Yes	Yes	Yes	8	8
166	2x42	3x46	Shared	4.79	6.47167	Yes	Yes	No	No	7	9
167	2x42	4x45	Shared	6.04	4.03167	Yes	Yes	No	No	7	5
168	2x45	4x46	Shared	14.62	10.9517	No	No	No	No	9	7
169	2x45	4x50	Shared	6.78	5.65	No	No	Yes	Yes	9	9
170	2x50	7x46	Shared	10.43	7.36167	Yes	Yes	No	No	9	8
171	2x53	3x32	Shared	5.97	5.77333	Yes	Yes	No	Yes	6	6
172	2x53	3x35	Shared	21.75	6.64667	Yes	Yes	No	No	6	7
173	2x53	7x42	Shared	12.38	18.3967	Yes	Yes	Yes	Yes	6	7
174	2x57	7x42	Shared	4.69	11.3167	No	Yes	Yes	Yes	7	7
175	2x59	E1x52	Shared	12.86	5.18167	No	No	Yes	Yes	5	6
176	2x59	3x28	Shared	3.93	5.67833	No	No	No	No	5	5
177	2x63	E1x50	Shared	10.95	5.71333	No	No	Yes	Yes	5	8
178	E1x49	E1x51	Shared	4.58	3.56	No	No	No	No	4	4
179	E1x49	E2	Shared	11.22	4.49333	No	No	Yes	Yes	4	3
180	E1x50	E1x52	Shared	11.02	16.0317	Yes	Yes	Yes	Yes	8	6
181	3x25	E1x50	Shared	3.92	9.79333	No	No	Yes	Yes	9	8
182	E1x50	E2	Shared	6.93	4.52667	Yes	Yes	Yes	Yes	8	3
183	E1x50	E2x50	Shared	18.28	3.485	Yes	Yes	No	No	8	9
184	3x22	E2	Shared	5.23	5.75167	No	No	Yes	Yes	3	3
185	3x25	E2x50	Shared	7.28	6.06667	No	No	No	No	9	9
186	3x29	Lig	Shared	5.66	3.96833	No	No	Yes	Yes	5	0
187	3x30	4x62	Shared	6.02	3.26167	No	No	No	No	6	5
188	3x32	7x42	Shared	4.6	6.13167	No	Yes	Yes	Yes	6	7
189	3x32	Lig	Shared	11.06	12.41	No	Yes	Yes	Yes	6	0
190	3x34	4x50	Shared	4.7	4.39333	No	Yes	Yes	Yes	5	9
191	3x36	3x37	Shared	10.54	4.05167	Yes	Yes	Yes	Yes	7	6
192	3x36	6x48	Shared	7.67	7.10833	Yes	Yes	Yes	Yes	7	8
193	3x36	Lig	Shared	8.14	7.735	Yes	Yes	Yes	Yes	7	0
194	3x37	4x56	Shared	9.18	7.64833	Yes	Yes	Yes	No	6	4
195	3x37	4x57	Shared	5.02	4.29167	Yes	Yes	No	No	6	7
196	3x38	4x50	Shared	9.7	17.5883	Yes	No	Yes	Yes	7	9
197	3x38	4x53	Shared	9.59	3.99833	Yes	No	No	Yes	7	7
198	3x40	5x50	Shared	8.47	2.895	No	No	No	No	8	9
199	3x40	6x44	Shared	16.33	2.80167	No	No	Yes	No	8	9
200	3x47	5x54	Shared	4.64	7.74	No	No	Yes	No	9	7
201	3x47	5x58	Shared	10.17	6.35833	No	No	No	Yes	9	9
202	3x49	I2x57	Shared	11.91	7.94333	No	No	No	Yes	8	5
203	3x51	3x55	Shared	10.09	9.04167	Yes	Yes	No	No	8	7
204	3x51	5x57	Shared	4.03	4.92833	Yes	Yes	No	No	8	7
205	3x51	5x60	Shared	4.13	7.88667	Yes	Yes	No	No	8	4
206	3x53	I2x57	Shared	6.91	4.84	No	No	No	Yes	8	5
207	3x54	5x61	Shared	4.61	7.16667	No	No	No	No	8	9
208	3x55	3x56	Shared	9.69	8.765	No	No	No	No	7	5
209	3x55	5x64	Shared	6.07	6.57833	No	No	No	Yes	7	5
210	4x38	4x39	Shared	12.97	1.68	No	Yes	No	No	6	3
211	4x56	5x42	Shared	6.31	1.68333	Yes	No	No	No	4	4
212	4x61	E2x52	Shared	7.36	4.57167	No	No	No	Yes	3	5
213	4x63	4x64	Shared	8.46	5.51167	No	No	No	No	4	4
214	4x64	E2	Shared	23.02	15.78	No	No	Yes	Yes	4	3
215	E2	E2	Shared	57.61	44.205	Yes	Yes	Yes	Yes	3	3
216	E2	E2x51	Shared	5.81	3.795	Yes	Yes	No	No	3	4
217	E2x51	Lig	Shared	8.26	5.40167	No	No	Yes	Yes	4	0
218	E2	E2x52	Shared	15.27	4.59	Yes	Yes	No	Yes	3	5
219	E2x52	Lig	Shared	8	3.78167	No	Yes	Yes	Yes	5	0
220	5x35	E2	Shared	38.4	7.78333	No	No	Yes	Yes	3	3
221	5x39	E2	Shared	15.03	9.85667	No	Yes	Yes	Yes	7	3
222	5x36	Lig	Shared	23.3	5.91833	No	No	Yes	Yes	4	0
223	5x37	6x59	Shared	9.52	2.36833	No	No	No	No	3	4
224	5x42	5x46	Shared	8.21	6.25167	No	No	No	No	4	4
225	5x44	6x52	Shared	5.16	10.1467	No	No	Yes	No	5	7
226	5x47	6x49	Shared	8.53	5.33167	No	No	No	Yes	8	5
227	5x47	6x52	Shared	20.63	10.8317	No	No	Yes	No	8	7
228	5x54	6x41	Shared	4.61	2.81833	Yes	No	No	No	7	7
229	6x26	6x30	Shared	11.63	4.07333	No	No	Yes	Yes	4	6
230	6x26	6x31	Shared	13.61	8.665	No	No	No	No	4	5
231	6x27	6x29	Shared	4.59	7.25	No	No	No	No	3	5
232	6x35	6x39	Shared	5.01	0.835	No	No	No	No	6	6
233	6x36	7x56	Shared	5.65	3.505	No	No	No	No	8	6
234	6x44	6x48	Shared	18.04	8.68833	Yes	No	Yes	Yes	9	8
235	6x46	6x47	Shared	4.19	1.02833	No	No	No	No	6	8
236	6x47	7x45	Shared	11.02	7.35	No	No	Yes	No	8	9
237	6x48	7x41	Shared	18.19	8.75167	Yes	Yes	No	No	8	7
238	6x48	7x45	Shared	6.78	9.79333	Yes	Yes	Yes	No	8	9
239	6x49	6x50	Shared	4.93	3.04167	No	Yes	No	No	5	9
240	6x49	6x53	Shared	4.28	2.66333	No	Yes	No	No	5	5
241	6x51	6x55	Shared	14.5	6.58833	Yes	Yes	No	Yes	6	6
242	6x51	7x41	Shared	5.19	3.925	Yes	Yes	No	No	6	7
243	6x54	7x34	Shared	13.93	3.77833	No	No	No	No	4	4
244	E3	Lig	Shared	14.34	3.66	No	No	Yes	Yes	2	0
245	7x27	7x30	Shared	5.9	3.685	No	No	No	No	1	4
246	7x34	Lig	Shared	17.13	9.31833	No	No	Yes	Yes	4	0
247	7x38	7x42	Shared	5.05	3.605	No	No	Yes	Yes	6	7
248	7x49	7x53	Shared	4.65	4.45833	No	No	Yes	Yes	9	9
249	8x47	8x49	Shared	4.04	2.235	No	No	No	Yes	8	5
250	8x47	8x50	Shared	13.14	4.625	No	No	Yes	Yes	8	8
251	Lig	Lig	Shared	140.66	18.96	Yes	Yes	Yes	Yes	0	0
252	1x60	8x57	Shared	3.79	2.94333	Yes	Yes	Yes	No	6	5
253	2x62	E1x52	Shared	3.73	1.24333	No	No	Yes	Yes	5	6
254	3x51	3x52	Shared	3.52	3.215	Yes	Yes	No	No	8	4
255	7x27	7x28	Shared	3.5	2.33333	No	No	No	No	1	3
256	2x49	3x38	Shared	3.36	1.96	No	No	Yes	No	8	7
257	6x50	7x40	Shared	3.28	4.65333	No	No	No	No	9	7
258	3x48	5x57	Shared	3.27	2.52833	No	No	No	No	6	7
259	1x54	2x47	Shared	3.25	2.435	Yes	No	No	No	7	9
260	2x41	4x42	Shared	3.25	3.51667	No	No	No	No	5	7
261	4x38	4x40	Shared	3.2	1.24333	No	Yes	No	No	6	4
262	3x27	3x30	Shared	3.17	0.53	No	No	No	No	5	6
263	1x34	1x38	Shared	3.07	0.511667	No	No	No	No	5	5
264	1x38	7x39	Shared	3.07	7.64833	No	No	No	Yes	5	5
265	3x21	E1x50	Shared	2.81	2.58	No	No	Yes	Yes	7	8
266	1x47	2x55	Shared	2.77	2.075	No	No	No	No	6	5
267	3x26	4x65	Shared	2.77	2.53333	No	No	No	No	6	4
268	2x46	2x50	Shared	2.75	3.395	No	No	Yes	Yes	9	9
269	2x42	4x42	Shared	2.67	2.00167	Yes	Yes	No	No	7	7
270	1x39	7x39	Shared	2.52	7.045	Yes	Yes	No	Yes	7	5
271	7x51	7x55	Shared	2.51	1.67667	No	No	No	No	6	7
272	5x44	5x48	Shared	2.44	3.65333	No	No	No	No	5	4
273	1x46	7x47	Shared	1.96	3.26667	No	No	No	Yes	8	8
274	1x48	1x49	Shared	1.96	1.57333	No	No	No	No	5	8
275	5x32	5x33	Shared	1.86	1.385	No	No	No	No	2	2
276	1x42	7x47	Shared	1.71	3.415	No	No	No	Yes	7	8
277	7x27	7x29	Shared	1.68	0.84	No	No	No	No	1	1
278	1x45	7x47	Shared	1.64	0.818333	No	No	No	Yes	4	8
279	6x59	6x60	Shared	1.62	4.265	No	No	No	No	4	4
280	I2x51	I2x52	Shared	1.45	1.45667	No	No	No	No	5	4
281	3x34	4x54	Shared	1.43	6.315	No	Yes	No	No	5	3
282	1x39	2x57	sst_on	0	3.90667	Yes	Yes	No	Yes	7	7
283	1x50	2x51	sst_on	0	6.575	No	No	No	Yes	9	7
284	1x55	1x60	sst_on	0	4.17333	No	No	Yes	Yes	3	6
285	1x56	8x50	sst_on	0	4.58833	No	No	Yes	Yes	7	8
286	1x57	2x44	sst_on	0	6.9	No	No	No	No	7	6
287	2x40	I1x48	sst_on	0	3.64667	Yes	Yes	No	No	8	5
288	2x41	I1x50	sst_on	0	4.13	No	No	Yes	No	5	7
289	2x37	2x39	sst_on	0	3.40167	No	No	No	No	7	8
290	2x38	2x42	sst_on	0	4.68667	No	No	Yes	Yes	4	7
291	2x42	3x49	sst_on	0	10.1517	Yes	Yes	No	No	7	8
292	2x45	3x42	sst_on	0	5.77167	No	No	No	No	9	8
293	2x46	3x42	sst_on	0	3.96833	No	No	No	No	9	8
294	2x50	3x39	sst_on	0	3.92667	Yes	Yes	No	No	9	9
295	2x50	7x50	sst_on	0	3.75667	Yes	Yes	No	No	9	9
296	2x52	3x35	sst_on	0	7.325	No	No	No	No	7	7
297	2x53	7x46	sst_on	0	3.96167	Yes	Yes	No	No	6	8
298	2x57	2x58	sst_on	0	3.74333	No	Yes	No	No	7	8
299	2x60	7x42	sst_on	0	4.13167	No	No	Yes	Yes	6	7
300	2x60	Lig	sst_on	0	11.095	No	No	Yes	Yes	6	0
301	2x63	Lig	sst_on	0	4.64333	No	No	Yes	Yes	5	0
302	2x64	7x35	sst_on	0	5.115	Yes	No	No	Yes	4	2
303	3x24	E1x52	sst_on	0	3.35	No	No	Yes	Yes	6	6
304	3x22	3x26	sst_on	0	3.66667	No	No	No	No	3	6
305	3x31	3x35	sst_on	0	3.69333	No	No	No	No	5	7
306	3x34	4x53	sst_on	0	4.31333	No	Yes	No	Yes	5	7
307	3x34	4x57	sst_on	0	4.91167	No	Yes	No	No	5	7
308	3x37	4x53	sst_on	0	3.3	Yes	Yes	No	Yes	6	7
309	3x37	5x43	sst_on	0	3.89	Yes	Yes	No	No	6	4
310	3x43	7x49	sst_on	0	4.34667	No	No	No	No	9	9
311	3x43	7x53	sst_on	0	5.86	No	No	Yes	Yes	9	9
312	3x46	3x50	sst_on	0	8.54	No	No	Yes	No	9	9
313	3x47	5x57	sst_on	0	3.15333	No	No	No	No	9	7
314	3x50	5x58	sst_on	0	7.715	Yes	No	No	Yes	9	9
315	3x50	7x53	sst_on	0	5.48833	Yes	No	Yes	Yes	9	9
316	3x56	I2x52	sst_on	0	8.09833	No	No	No	No	5	4
317	4x59	4x60	sst_on	0	4.92667	No	No	No	No	4	8
318	4x60	5x39	sst_on	0	3.85333	No	No	No	Yes	8	7
319	E2	E2x50	sst_on	0	5.01833	Yes	Yes	No	No	3	9
320	5x36	E2	sst_on	0	6.96	No	No	Yes	Yes	4	3
321	E2	Lig	sst_on	0	5.57333	Yes	Yes	Yes	Yes	3	0
322	5x39	Lig	sst_on	0	4.76833	No	Yes	Yes	Yes	7	0
323	5x40	6x55	sst_on	0	4.49167	No	No	No	Yes	5	6
324	5x43	6x52	sst_on	0	4.16333	No	No	Yes	No	4	7
325	5x43	Lig	sst_on	0	6.34167	No	No	Yes	Yes	4	0
326	5x44	5x47	sst_on	0	7.50167	No	No	No	No	5	8
327	5x45	5x48	sst_on	0	3.24667	No	No	No	No	4	4
328	5x461	5x50	sst_on	0	3.045	No	No	No	No	6	9
329	5x51	6x44	sst_on	0	4.19833	No	No	Yes	No	6	9
330	5x54	5x58	sst_on	0	6.24667	Yes	No	No	Yes	7	9
331	5x58	6x37	sst_on	0	11.7783	No	Yes	No	No	9	8
332	5x58	6x40	sst_on	0	5.38667	No	Yes	No	Yes	9	8
333	5x62	6x30	sst_on	0	3.24667	No	Yes	Yes	Yes	5	6
334	5x62	6x34	sst_on	0	3.32833	No	Yes	No	No	5	7
335	5x66	6x26	sst_on	0	14.0333	No	No	No	No	4	4
336	5x66	6x30	sst_on	0	12.96	No	No	Yes	Yes	4	6
337	6x40	7x52	sst_on	0	5.39333	No	Yes	No	No	8	8
338	6x40	7x53	sst_on	0	16.83	No	Yes	Yes	Yes	8	9
339	6x45	6x49	sst_on	0	4.42	No	No	No	Yes	6	5
340	6x51	7x38	sst_on	0	4.31	Yes	Yes	No	No	6	6
341	6x51	Lig	sst_on	0	9.49333	Yes	Yes	Yes	Yes	6	0
342	7x31	7x35	sst_on	0	3.22667	No	No	No	Yes	3	2
343	7x42	Lig	sst_on	0	4.26167	Yes	Yes	Yes	Yes	7	0
344	7x45	7x49	sst_on	0	8.4	Yes	No	No	No	9	9
345	7x52	7x53	sst_on	0	4.68833	No	No	Yes	Yes	8	9
346	7x54	8x50	sst_on	0	4.85833	No	No	Yes	Yes	7	8
347	2x39	I2x57	sst_on	0	3.45	No	No	No	Yes	8	5
348	2x43	8x50	sst_on	0	7.72333	No	No	Yes	Yes	8	8
349	2x56	3x32	sst_on	0	5.99333	No	No	No	Yes	6	6
350	3x37	Lig	sst_on	0	3.995	Yes	Yes	Yes	Yes	6	0
351	5x39	E2x52	sst_on	0	3.08167	No	Yes	No	Yes	7	5
352	5x65	6x30	sst_on	0	4.09833	No	No	Yes	Yes	8	6
353	5x66	I3	sst_on	0	5.67667	No	No	No	Yes	4	0
354	6x27	I3	sst_on	0	3.39333	No	No	No	Yes	3	0
355	6x30	6x31	sst_on	0	4.725	Yes	Yes	No	No	6	5
356	6x54	7x37	sst_on	0	5.57	No	No	No	No	4	7
357	6x55	Lig	sst_on	0	9.275	No	Yes	Yes	Yes	6	0
358	7x36	7x39	sst_on	0	3.17833	No	No	No	Yes	5	5
359	2x40	I1x51	sst_on	0	5.12833	Yes	Yes	No	No	8	7
360	4x38	I2x57	sst_on	0	3.55333	No	Yes	No	Yes	6	5
361	5x32	E2	sst_on	0	3.17167	No	No	Yes	Yes	2	3
362	8x49	8x52	sst_on	0	4.54833	No	Yes	No	No	5	5
363	1x32	1x35	sst_on	0	4.375	Yes	Yes	No	Yes	3	5
364	1x32	7x35	sst_on	0	4.595	Yes	Yes	No	Yes	3	2
365	2x37	I2x57	sst_on	0	3.88	No	No	No	Yes	7	5
366	I2x55	I2x56	sst_on	0	4.37	No	No	No	No	4	3
367	4x47	4x50	sst_on	0	3.415	No	No	Yes	Yes	4	9
368	5x32	5x35	sst_on	0	3.705	No	No	No	No	2	3
369	6x24	I3	sst_on	0	6.655	No	No	No	Yes	2	0
370	6x36	6x40	sst_on	0	4.87	No	No	No	Yes	8	8
371	6x55	6x58	sst_on	0	3.3	No	Yes	No	No	6	4
372	7x33	E3	sst_on	0	3.65	No	No	No	No	4	2
373	8x48	8x52	sst_on	0	2.995	No	No	No	No	5	5
374	I2x53	I2x57	sst_on	0	2.92167	No	No	No	Yes	5	5
375	5x65	6x33	sst_on	0	2.915	No	No	No	No	8	8
376	1x42	7x39	sst_on	0	2.87167	No	No	No	Yes	7	5
377	5x45	5x49	sst_on	0	2.845	No	No	No	No	4	5
378	3x41	4x49	sst_on	0	2.83833	No	No	No	No	6	6
379	8x49	8x53	sst_on	0	2.73167	No	Yes	No	No	5	5
380	2x54	7x47	sst_on	0	2.7	No	No	No	Yes	6	8
381	3x45	4x49	sst_on	0	2.67333	No	No	No	No	7	6
382	3x44	5x50	sst_on	0	2.625	No	No	No	No	7	9
383	3x33	3x36	sst_on	0	2.56667	No	No	Yes	Yes	4	7
384	1x53	1x57	sst_on	0	2.56	No	No	No	No	9	7
385	E1	E2	sst_on	0	2.42667	No	No	Yes	Yes	4	3
386	2x41	4x43	sst_on	0	2.42333	No	No	No	No	5	1
387	3x41	4x53	sst_on	0	2.42	No	No	No	Yes	6	7
388	3x44	5x53	sst_on	0	2.36	No	No	No	No	7	6
389	8x48	8x51	sst_on	0	2.24667	No	No	No	No	5	8
390	2x44	2x48	sst_on	0	2.17167	No	No	No	No	6	7
391	6x28	6x32	sst_on	0	2.155	No	No	No	No	4	7
392	6x39	7x52	sst_on	0	2.13	No	No	No	No	6	8
393	I2x52	I2x56	sst_on	0	2.12667	No	No	No	No	4	3
394	7x55	7x56	sst_on	0	2.03167	No	No	No	No	7	6
395	1x31	1x32	sst_on	0	1.98667	No	No	Yes	Yes	4	3
396	1x42	7x43	sst_on	0	1.97833	No	No	No	No	7	5
397	4x38	4x41	sst_on	0	1.94	No	Yes	No	No	6	5
398	6x54	6x57	sst_on	0	1.93	No	No	No	No	4	4
399	5x62	6x37	sst_on	0	1.82333	No	Yes	No	No	5	8
400	6x24	6x25	sst_on	0	1.79	No	No	No	No	2	3
401	6x60	6x61	sst_on	0	1.78833	No	No	No	No	4	3
402	5x64	5x67	sst_on	0	1.785	No	Yes	No	No	5	5
403	5x64	5x68	sst_on	0	1.78	No	Yes	No	No	5	0
404	5x55	6x41	sst_on	0	1.77333	No	No	No	No	5	7
405	3x41	4x52	sst_on	0	1.74667	No	No	No	No	6	4
406	2x66	E1x49	sst_on	0	1.715	No	No	No	No	5	4
407	4x48	4x51	sst_on	0	1.71	No	No	No	No	4	4
408	6x42	6x46	sst_on	0	1.67	No	No	No	No	5	6
409	6x32	6x35	sst_on	0	1.65333	No	No	No	No	7	6
410	7x30	7x33	sst_on	0	1.65	No	No	No	No	4	4
411	1x32	1x36	sst_on	0	1.60333	Yes	Yes	No	No	3	5
412	3x30	4x61	sst_on	0	1.55	No	No	No	No	6	3
413	3x56	I2x50	sst_on	0	1.53	No	No	No	No	5	8
414	1x56	1x60	sst_on	0	1.47167	No	No	Yes	Yes	7	6
415	5x38	5x41	sst_on	0	1.47	No	No	No	No	4	5
416	5x63	5x64	sst_on	0	1.45333	No	No	No	Yes	3	5
417	6x43	6x47	sst_on	0	1.425	No	No	No	No	7	8
418	5x58	5x61	sst_on	0	1.41167	No	Yes	No	No	9	9
419	5x40	6x56	sst_on	0	1.25833	No	No	No	No	5	5
420	4x40	4x44	sst_on	0	1.24	No	No	No	No	4	1
421	5x37	5x38	sst_on	0	1.21333	No	No	No	No	3	4
422	6x23	I3	sst_on	0	1.19833	No	No	No	Yes	3	0
423	5x36	6x59	sst_on	0	1.17	No	No	No	No	4	4
424	1x40	1x43	sst_on	0	1.13833	No	No	No	No	5	6
425	1x52	8x54	sst_on	0	1.015	No	No	No	No	6	6
426	1x35	7x32	sst_on	0	0.855	No	Yes	No	No	5	1
427	1x33	1x37	sst_on	0	0.855	No	No	No	No	4	6
428	1x28	7x28	sst_on	0	0.805	No	No	No	No	0	3
429	1x43	1x44	sst_on	0	0.795	No	No	No	No	6	4
430	5x52	5x53	sst_on	0	0.76	No	No	No	No	4	6
431	5x59	5x62	sst_on	0	0.745	No	No	No	Yes	4	5
432	1x38	1x41	sst_on	0	0.715	No	No	No	No	5	5
433	I2x54	I2x57	sst_on	0	0.691667	No	No	No	Yes	4	5
434	6x43	7x48	sst_on	0	0.566667	No	No	No	No	7	6
435	6x38	6x39	sst_on	0	0.516667	No	No	No	No	4	6
436	5x52	5x56	sst_on	0	0.491667	No	No	No	No	4	5
437	1x37	1x40	sst_on	0	0.356667	No	No	No	No	6	5
438	1x30	1x34	sst_on	0	0.265	No	No	No	No	4	5
439	8x56	8x57	sst_on	0	0.246667	No	No	Yes	No	4	5
440	4x50	4x51	sst_on	0	0.235	Yes	Yes	No	No	9	4
441	5x34	5x35	sst_on	0	0.216667	No	No	No	No	1	3

Orange: nodes, hubs and links specific of sst_off network

Green: nodes, hubs and links shared by both networks

Purple: nodes, hubs and links specific of sst_on network

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Owner: the name of the network the hub belong to or "Shared" if the corresponding hub is present in both networks.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub in the corresponding network.

Num Of Links: the number of links of the corresponding hub in the corresponding network.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Owner	sst_off Avg Int. Strength	sst_on Avg Int. Strength	sst_off Num Of Links	sst_on Num Of Links	ConSurf
1	1x54	sst_off	4.7225	2.35667	4	2	7
2	I1x50	sst_off	7.565	4.13	4	1	7
3	2x64	sst_off	5.012	5.115	5	1	4
4	3x38	sst_off	6.388	7.84889	5	3	7
5	3x50	sst_off	6.142	7.24778	5	3	9
6	4x56	sst_off	5.39	4.66583	4	2	4
7	5x54	sst_off	4.9025	5.60167	4	3	7
8	6x44	sst_off	10.7125	5.22944	4	3	9
9	6x52	sst_off	10.122	8.38056	5	3	7
10	7x45	sst_off	6.3975	8.51444	4	3	9
11	8x57	sst_off	3.385	1.595	4	2	5
12	1x32	Shared	8.685	3.14	4	4	3
13	1x39	Shared	4.948	4.38208	5	4	7
14	1x60	Shared	7.985	3.605	4	4	6
15	2x40	Shared	7.9175	4.13458	4	4	8
16	2x42	Shared	5.8975	5.46867	4	5	7
17	2x50	Shared	6.178	5.304	5	5	9
18	2x53	Shared	10.68	8.69458	4	4	6
19	E1x50	Shared	8.985	7.02167	6	6	8
20	E1x52	Shared	9.7925	6.45167	4	4	6
21	3x36	Shared	8.56	5.36542	4	4	7
22	3x37	Shared	6.71	4.52944	5	6	6
23	3x51	Shared	4.96	6.26792	6	4	8
24	4x50	Shared	5.865	6.25633	4	5	9
25	E2	Shared	21.7409	11.2091	11	15	3
26	6x30	Shared	6.7725	5.82067	4	5	6
27	6x48	Shared	10.7283	8.58542	6	4	8
28	6x51	Shared	7.376	6.07917	5	4	6
29	7x42	Shared	6.11167	7.97389	6	6	7
30	7x53	Shared	6.716	7.465	5	5	9
31	8x50	Shared	8.474	4.96861	5	6	8
32	Lig	Shared	23.549	7.87158	20	19	0
33	1x35	sst_on	6.49	3.12542	3	4	5
34	2x51	sst_on	6.41333	4.31	3	4	7
35	2x57	sst_on	4.09333	5.89667	3	4	7
36	3x32	sst_on	7.21	7.57708	3	4	6
37	3x34	sst_on	4.57667	4.98333	3	4	5
38	I2x57	sst_on	8.36	4.01021	3	8	5
39	4x38	sst_on	8.085	2.10417	2	4	6
40	4x53	sst_on	9.59	3.50792	1	4	7
41	E2x52	sst_on	10.21	4.00625	3	4	5
42	5x39	sst_on	11.405	5.39	2	4	7
43	5x58	sst_on	8.9	6.48278	2	6	9
44	5x62	sst_on	0	2.28583	0	4	5
45	5x64	sst_on	3.87	2.89917	2	4	5
46	I3	sst_on	0	4.23083	0	4	0
47	6x40	sst_on	5.96	8.12	1	4	8
48	6x49	sst_on	5.91333	3.86417	3	4	5
49	6x55	sst_on	14.5	5.91375	1	4	6
50	7x35	sst_on	11.16	4.29708	2	4	2
51	7x39	sst_on	2.795	5.18583	2	4	5
52	7x47	sst_on	1.77	2.55	3	4	8
53	8x49	sst_on	6.48	3.36958	3	4	5

Orange: nodes, hubs and links specific of sst_off network

Green: nodes, hubs and links shared by both networks

Purple: nodes, hubs and links specific of sst_on network

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Owner: the name of the network the link belong to or "Shared" if the corresponding link is present in both networks.

Recurrence: the relative Recurrence in the filtered pool of shortest paths.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Owner	sst_off Recurrence	sst_on Recurrence	sst_off Hub1?	sst_on Hub1?	sst_off Hub2?	sst_on Hub2?	ConSurf1	ConSurf2
1	1x39	2x61	sst_off	10.4219	0.942492	Yes	Yes	No	No	7	6
2	1x39	7x42	sst_off	16.0705	0	Yes	Yes	Yes	Yes	7	7
3	3x32	7x42	sst_off	14.9179	0.163124	No	Yes	Yes	Yes	6	7
4	2x54	2x57	sst_off	28.5528	0	No	No	No	Yes	6	7
5	1x47	2x54	sst_off	26.0792	0	No	No	No	No	6	6
6	1x47	2x51	sst_off	25.0462	3.32721	No	No	No	Yes	6	7
7	2x53	3x35	sst_off	100	5.14746	Yes	Yes	No	No	6	7
8	2x50	3x35	sst_off	98.2549	0	Yes	Yes	No	No	9	7
9	2x50	7x49	sst_off	94.6667	0	Yes	Yes	No	No	9	9
10	7x53	8x50	sst_off	44.4493	0	Yes	Yes	Yes	Yes	9	8
11	8x50	I1x50	sst_off	32.3149	0	Yes	Yes	Yes	No	8	7
12	8x53	I1x50	sst_off	28.1885	0	No	No	Yes	No	5	7
13	1x60	8x53	sst_off	21.7952	0	Yes	Yes	No	No	6	5
14	1x54	2x51	sst_off	24.1003	3.32721	Yes	No	No	Yes	7	7
15	1x54	2x44	sst_off	25.0462	0	Yes	No	No	No	7	6
16	1x60	8x56	sst_off	10.1881	0	Yes	Yes	No	No	6	4
17	2x43	7x53	sst_off	69.7564	0	No	No	Yes	Yes	8	9
18	2x43	3x46	sst_off	68.5332	0	No	No	No	No	8	9
19	3x46	6x37	sst_off	52.1094	0	No	No	No	No	9	8
20	3x50	6x37	sst_off	50.7122	0	Yes	No	No	No	9	8
21	2x44	2x45	sst_off	22.067	0	No	No	No	No	6	9
22	2x45	4x50	sst_off	15.978	7.93869	No	No	Yes	Yes	9	9
23	3x29	Lig	sst_off	15.9019	0.841511	No	No	Yes	Yes	5	0
24	3x29	E2x50	sst_off	12.3953	0	No	No	No	No	5	9
25	E1x50	E2x50	sst_off	10.2044	0.0181249	Yes	Yes	No	No	8	9
26	E1x50	E1x52	sst_off	20.0391	9.021	Yes	Yes	Yes	Yes	8	6
27	2x59	E1x52	sst_off	18.7507	3.53953	No	No	Yes	Yes	5	6
28	E2x51	Lig	sst_off	22.1975	0.779369	No	No	Yes	Yes	4	0
29	E2	E2x51	sst_off	21.2134	0.0699102	Yes	Yes	No	No	3	4
30	E1x50	E2	sst_off	20.6807	7.34574	Yes	Yes	Yes	Yes	8	3
31	E2x52	Lig	sst_off	24.2144	4.33961	No	Yes	Yes	Yes	5	0
32	E2	E2x52	sst_off	22.1975	0.38839	Yes	Yes	No	Yes	3	5
33	3x36	6x52	sst_off	23.5566	0	Yes	Yes	Yes	No	7	7
34	6x44	6x48	sst_off	10.0794	9.06243	Yes	No	Yes	Yes	9	8
35	5x47	6x52	sst_off	38.3549	8.80609	No	No	Yes	No	8	7
36	5x47	5x51	sst_off	22.1757	0	No	No	No	No	8	6
37	5x51	5x54	sst_off	16.6957	0	No	No	Yes	No	6	7
38	3x50	6x34	sst_off	41.6603	0	Yes	No	No	No	9	7
39	6x30	6x34	sst_off	40.2088	0	Yes	Yes	No	No	6	7
40	3x54	6x30	sst_off	29.6999	0	No	No	Yes	Yes	8	6
41	3x54	5x61	sst_off	28.1396	1.40856	No	No	No	No	8	9
42	3x51	5x61	sst_off	26.6989	0	Yes	Yes	No	No	8	9
43	5x36	Lig	sst_off	11.8136	6.02263	No	No	Yes	Yes	4	0
44	5x44	6x52	sst_off	11.1721	5.86986	No	No	Yes	No	5	7
45	5x47	6x49	sst_off	13.9393	7.40271	No	No	No	Yes	8	5
46	6x51	6x52	sst_off	15.9128	0	Yes	Yes	Yes	No	6	7
47	7x41	7x42	sst_off	44.2699	0	No	No	Yes	Yes	7	7
48	6x48	7x41	sst_off	27.4818	3.57836	Yes	Yes	No	No	8	7
49	1x53	7x53	sst_off	15.2387	0	No	No	Yes	Yes	9	9
50	1x54	2x47	sst_off	14.0426	1.6649	Yes	No	No	No	7	9
51	1x53	2x47	sst_off	13.836	0	No	No	No	No	9	9
52	6x51	7x41	sst_off	16.3368	3.59908	Yes	Yes	No	No	6	7
53	6x48	6x52	sst_off	15.3855	0	Yes	Yes	Yes	No	8	7
54	3x32	Lig	Shared	75.0897	15.1187	No	Yes	Yes	Yes	6	0
55	2x57	7x42	Shared	33.8154	25.6933	No	Yes	Yes	Yes	7	7
56	2x53	3x32	Shared	60.3729	13.705	Yes	Yes	No	Yes	6	6
57	7x49	7x53	Shared	94.6178	98.6795	No	No	Yes	Yes	9	9
58	2x42	3x46	Shared	17.5601	58.8669	Yes	Yes	No	No	7	9
59	3x36	Lig	Shared	46.6402	72.5512	Yes	Yes	Yes	Yes	7	0
60	3x36	3x37	Shared	21.2896	24.6472	Yes	Yes	Yes	Yes	7	6
61	3x36	6x48	Shared	12.6509	97.2424	Yes	Yes	Yes	Yes	7	8
62	2x53	7x42	Shared	41.133	15.4838	Yes	Yes	Yes	Yes	6	7
63	1x39	7x39	sst_on	4.92008	10.862	Yes	Yes	No	Yes	7	5
64	1x39	2x57	sst_on	0	20.16	Yes	Yes	No	Yes	7	7
65	2x53	7x46	sst_on	0	22.77	Yes	Yes	No	No	6	8
66	2x50	7x46	sst_on	0.587148	21.2242	Yes	Yes	No	No	9	8
67	1x50	2x50	sst_on	6.93161	11.5067	No	No	Yes	Yes	9	9
68	7x42	Lig	sst_on	0	38.1321	Yes	Yes	Yes	Yes	7	0
69	6x48	7x45	sst_on	8.51365	100	Yes	Yes	Yes	No	8	9
70	7x45	7x49	sst_on	0	99.3786	Yes	No	No	No	9	9
71	3x50	7x53	sst_on	0	72.7117	Yes	No	Yes	Yes	9	9
72	3x46	3x50	sst_on	0	59.3822	No	No	Yes	No	9	9
73	2x38	2x42	sst_on	0	27.8165	No	No	Yes	Yes	4	7
74	2x38	I2x57	sst_on	2.40296	27.1588	No	No	No	Yes	4	5
75	2x37	I2x57	sst_on	0	40.1724	No	No	No	Yes	7	5
76	2x37	2x40	sst_on	1.73426	38.795	No	No	Yes	Yes	7	8
77	2x40	8x50	sst_on	3.10971	34.3829	Yes	Yes	Yes	Yes	8	8
78	1x56	8x50	sst_on	0	11.9417	No	No	Yes	Yes	7	8
79	2x42	3x49	sst_on	0	27.9149	Yes	Yes	No	No	7	8
80	3x49	I2x57	sst_on	5.70295	27.2675	No	No	No	Yes	8	5
81	3x37	Lig	sst_on	0	10.8335	Yes	Yes	Yes	Yes	6	0
82	3x37	4x53	sst_on	0	19.3185	Yes	Yes	No	Yes	6	7
83	3x34	4x50	sst_on	4.82222	11.8511	No	Yes	Yes	Yes	5	9
84	E2	Lig	sst_on	0	20.0357	Yes	Yes	Yes	Yes	3	0
85	5x43	Lig	sst_on	0	10.2923	No	No	Yes	Yes	4	0
86	3x50	5x58	sst_on	0	31.6952	Yes	No	No	Yes	9	9
87	3x47	5x58	sst_on	5.60509	24.6213	No	No	No	Yes	9	9
88	6x40	7x53	sst_on	0	26.206	No	Yes	Yes	Yes	8	9
89	5x58	6x40	sst_on	0	24.4349	No	Yes	No	Yes	9	8
90	3x47	5x57	sst_on	0	23.3267	No	No	No	No	9	7
91	3x51	5x57	sst_on	5.21366	20.4578	Yes	Yes	No	No	8	7
92	3x51	3x55	sst_on	8.6115	16.1156	Yes	Yes	No	No	8	7
93	5x43	6x52	sst_on	0	16.1182	No	No	Yes	No	4	7
94	5x58	6x37	sst_on	0	23.0237	No	Yes	No	No	9	8
95	5x62	6x37	sst_on	0	21.7084	No	Yes	No	No	5	8
96	5x62	6x30	sst_on	0	17.3791	No	Yes	Yes	Yes	5	6
97	5x66	6x30	sst_on	0	10.2509	No	No	Yes	Yes	4	6
98	8x47	8x50	sst_on	6.67065	10.7972	No	No	Yes	Yes	8	8

Here, those paths that begin and end at given residue pair(s) or that pass through a residue are used to generate a novel metapath. Such a path filtering is particularly recommended if some information on allosteric residues is available. The selection syntax for a residue pair ("Pairs") is C:C:c534,A:A:?600 (the lower-case "c" stands for cytosine and "?" indicates any non standard amino acid or nucleotide residue). Selection of more than one apical residue pair has the following syntax: C:C:c534,A:A:?600,C:C:c534,A:A:E41. Only one residue can be selected as a tail ("Tail"). For midway residue(s), each residue must be separated by a comma as well e.g. A:A:?600,A:A:E41.

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Node1	Node2	Owner	Net1LinkStrength	Net2LinkStrength	Comm1	Comm2	Node1Shell	Node2Shell
1x32	2x64	sst_off	4.43	0	1	4	1	1
1x32	E1	sst_off	10.52	0	1	4	1	1
1x32	Lig	sst_off	16.87	0	1	4	1	0
1x35	1x39	Shared	8.21	3.02	1	4	2	2
1x35	2x64	sst_off	4.47	0	1	4	2	1
1x35	7x35	Shared	6.79	4.25167	1	4	2	1
1x39	2x64	sst_off	5.05	0	1	0	2	1
1x39	7x42	sst_off	4.96	0	1	0	2	1
2x53	3x32	Shared	5.97	5.77333	1	1	2	1
2x53	7x42	Shared	12.38	18.3967	1	1	2	1
2x57	7x42	Shared	4.69	11.3167	0	0	2	1
2x60	3x28	sst_off	4.47	0	0	1	1	2
2x63	E1x50	Shared	10.95	5.71333	0	1	1	2
2x64	Lig	sst_off	7.94	0	1	0	1	0
E1	Lig	sst_off	13.91	0	1	0	1	0
E1x49	E2	Shared	11.22	4.49333	1	1	2	1
E1x50	E2	Shared	6.93	4.52667	1	1	2	1
E1x50	E2x50	Shared	18.28	3.485	1	1	2	2
3x22	E2	Shared	5.23	5.75167	0	1	2	1
3x29	E2x50	sst_off	4.86	0	1	0	1	2
3x29	Lig	Shared	5.66	3.96833	1	0	1	0
3x32	7x42	Shared	4.6	6.13167	1	1	1	1
3x32	Lig	Shared	11.06	12.41	1	1	1	0
3x36	3x37	Shared	10.54	4.05167	1	1	1	1
3x36	6x48	Shared	7.67	7.10833	1	1	1	2
3x36	6x52	sst_off	7.89	0	1	1	1	2
3x36	Lig	Shared	8.14	7.735	1	1	1	0
3x37	3x41	sst_off	4.29	0	0	1	1	2
3x37	4x56	Shared	9.18	7.64833	0	1	1	2
3x37	4x57	Shared	5.02	4.29167	0	1	1	2
3x37	5x461	sst_off	4.52	0	0	1	1	2
4x61	E2x52	Shared	7.36	4.57167	0	0	2	1
4x64	E2	Shared	23.02	15.78	1	1	2	1
E2	E2	Shared	57.61	44.205	1	1	1	1
E2	E2x51	Shared	5.81	3.795	1	1	1	1
E2x51	Lig	Shared	8.26	5.40167	1	1	1	0
E2	E2x52	Shared	15.27	4.59	1	1	1	1
E2x52	Lig	Shared	8	3.78167	1	1	1	0
5x35	E2	Shared	38.4	7.78333	0	1	2	1
5x39	E2	Shared	15.03	9.85667	1	1	1	1
5x36	5x40	sst_off	6.04	0	1	1	1	2
5x36	6x58	sst_off	5.09	0	1	1	1	2
5x36	Lig	Shared	23.3	5.91833	1	1	1	0
5x39	5x43	sst_off	7.78	0	1	1	1	1
6x48	6x51	sst_off	5.01	0	1	0	2	1
6x48	6x52	sst_off	8.68	0	1	0	2	2
6x48	7x41	Shared	18.19	8.75167	1	0	2	2
6x51	6x52	sst_off	8.25	0	1	1	1	2
6x51	6x55	Shared	14.5	6.58833	1	1	1	1
6x51	7x37	sst_off	3.93	0	1	1	1	2
6x51	7x41	Shared	5.19	3.925	1	1	1	2
6x54	7x33	sst_off	9.95	0	1	0	1	2
6x54	7x34	Shared	13.93	3.77833	1	0	1	1
6x54	Lig	sst_off	9.5	0	1	0	1	0
6x61	Lig	sst_off	4.41	0	0	0	1	0
7x31	E3	sst_off	6.69	0	1	0	1	1
E3	Lig	Shared	14.34	3.66	1	1	1	0
7x27	7x30	Shared	5.9	3.685	0	0	2	1
7x30	Lig	sst_off	5.4	0	1	0	1	0
7x31	Lig	sst_off	14.22	0	1	0	1	0
7x34	7x38	sst_off	7.87	0	1	1	1	2
7x34	Lig	Shared	17.13	9.31833	1	1	1	0
7x35	Lig	sst_off	15.53	0	1	4	1	0
7x38	7x42	Shared	5.05	3.605	0	0	2	1
7x41	7x42	sst_off	4.99	0	1	0	2	1
1x31	Lig	sst_off	3.74	0	0	0	1	0
3x29	4x65	sst_off	3.22	0	1	0	1	2
1x36	2x64	sst_off	3.17	0	0	0	2	1
5x40	6x59	sst_off	3.07	0	0	0	2	2
5x34	E2	sst_off	3.02	0	0	0	2	1
1x30	1x32	sst_off	2.92	0	0	0	2	1
5x32	Lig	sst_off	2.25	0	1	1	1	0
5x32	5x33	Shared	1.86	1.385	1	1	1	2
3x33	4x57	sst_off	1.76	0	0	0	2	2
3x33	4x61	sst_off	1.76	0	0	0	2	2
7x31	7x32	sst_off	1.74	0	1	0	1	2
6x59	6x60	Shared	1.62	4.265	0	0	2	2
1x39	2x57	sst_on	0	3.90667	1	0	2	2
2x60	7x42	sst_on	0	4.13167	0	1	1	1
2x60	Lig	sst_on	0	11.095	0	1	1	0
2x63	Lig	sst_on	0	4.64333	0	1	1	0
2x64	7x35	sst_on	0	5.115	1	0	1	1
3x37	4x53	sst_on	0	3.3	0	1	1	2
3x37	5x43	sst_on	0	3.89	0	1	1	1
4x60	5x39	sst_on	0	3.85333	0	0	2	1
E2	E2x50	sst_on	0	5.01833	1	1	1	2
5x36	E2	sst_on	0	6.96	1	1	1	1
E2	Lig	sst_on	0	5.57333	1	1	1	0
5x39	Lig	sst_on	0	4.76833	1	1	1	0
5x40	6x55	sst_on	0	4.49167	0	0	2	1
5x43	6x52	sst_on	0	4.16333	0	1	1	2
5x43	Lig	sst_on	0	6.34167	0	1	1	0
6x51	7x38	sst_on	0	4.31	1	1	1	2
6x51	Lig	sst_on	0	9.49333	1	1	1	0
7x31	7x35	sst_on	0	3.22667	1	0	1	1
7x42	Lig	sst_on	0	4.26167	1	1	1	0
2x56	3x32	sst_on	0	5.99333	0	0	2	1
3x37	Lig	sst_on	0	3.995	0	1	1	0
5x39	E2x52	sst_on	0	3.08167	1	1	1	1
6x54	7x37	sst_on	0	5.57	1	0	1	2
6x55	Lig	sst_on	0	9.275	0	1	1	0
5x32	E2	sst_on	0	3.17167	1	1	1	1
1x32	1x35	sst_on	0	4.375	1	4	1	2
1x32	7x35	sst_on	0	4.595	1	4	1	1
5x32	5x35	sst_on	0	3.705	1	1	1	2
6x55	6x58	sst_on	0	3.3	0	1	1	2
7x33	E3	sst_on	0	3.65	0	0	2	1
3x33	3x36	sst_on	0	2.56667	0	0	2	1
E1	E2	sst_on	0	2.42667	1	0	1	1
3x41	4x53	sst_on	0	2.42	0	0	2	2
1x31	1x32	sst_on	0	1.98667	0	0	1	1
6x54	6x57	sst_on	0	1.93	1	0	1	2
6x60	6x61	sst_on	0	1.78833	0	0	2	1
7x30	7x33	sst_on	0	1.65	1	0	1	2
1x32	1x36	sst_on	0	1.60333	1	4	1	2
5x36	6x59	sst_on	0	1.17	1	1	1	2
1x35	7x32	sst_on	0	0.855	1	4	2	2
5x34	5x35	sst_on	0	0.216667	0	0	2	2

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Difference Members
	Id	Description
	sst_off	sst2_off
	sst_on	sst2_on sst4_on

Network Difference
Value	sst_off	sst_on
I_min	3.92	3.02833
Number of Linked Nodes	251	263
Number of Specific Nodes	8 (3.19%)	20 (7.60%)
Number of Shared Nodes	243 (96.81%)	243 (92.40%)
Number of Links	281	296
Number of Specific Links	145 (51.60%)	160 (54.05%)
Number of Shared Links	136 (48.40%)	136 (45.95%)
Number of Hubs	32	42
Number of Specific Hubs	11 (34.38%)	21 (50.00%)
Number of Shared Hubs	21 (65.63%)	21 (50.00%)
Average % Shared Neighbours (Jaccard)	31.51
Average % Shared Neighbours (Otsuka)	40.18
Average % Shared Neighbours (Overlap Coefficient)	48.05
Average % Shared Cliques (k3-6)	51.16
Graphlets Similarity	0.567022

Paths Difference
Value	sst_off	sst_on
Number Of Nodes in MetaPath	56	43
Specific Nodes in MetaPath	34 (60.71%)	21 (48.84%)
Shared Nodes in MetaPath	243 (96.81%)	243 (96.81%)
Number Of Links MetaPath	62	45
Specific Links in MetaPath	53 (85.48%)	36 (80.00%)
Shared Links in MetaPath	136 (48.40%)	136 (48.40%)
Number of Shortest Paths	42195	64614
Length Of Smallest Path	3	3
Average Path Length	12.4209	13.5046
Length of Longest Path	29	27
Minimum Path Strength	1.57	0.388333
Average Path Strength	7.73778	6.03531
Maximum Path Strength	30.71	14.8567
Minimum Path Correlation	0.7	0.701667
Average Path Correlation	0.923476	0.909487
Maximum Path Correlation	1	0.985
Minimum % Of Corr. Nodes	5	4.54545
Average % Of Corr. Nodes	53.6156	42.7253
Maximum % Of Corr. Nodes	100	100
Minimum Path Hubs %	0	0
Average Path Hubs %	42.2297	50.2087
Maximum Path Hubs %	100	100

Details about the values in these tables can be found in the corresponding documentation page .

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