Orange: nodes, hubs and links specific of succinate_on_gp network

Green: nodes, hubs and links shared by both networks

Purple: nodes, hubs and links specific of succinate_off network

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Owner: the name of the network the hub belong to or "Shared" if the corresponding hub is present in both networks.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub in the corresponding network.

Num Of Links: the number of links of the corresponding hub in the corresponding network.

ConSurf: this column reports the ConSurf conservation grades of each hub.


Index Hub Owner succinate_on_gp Avg Int. Strength succinate_off Avg Int. Strength succinate_on_gp Num Of Links succinate_off Num Of Links ConSurf
1G.HN.11 succinate_on_gp00402
2G.HN.45 succinate_on_gp00404
3G.S1.02 succinate_on_gp500405
4G.S1.05 succinate_on_gp500409
5G.s1h1.05 succinate_on_gp00409
6G.H1.01 succinate_on_gp1000409
7G.H1.03 succinate_on_gp00409
8G.H1.04 succinate_on_gp1000509
9G.S2.08 succinate_on_gp1000503
10G.S3.03 succinate_on_gp1000604
11G.S3.05 succinate_on_gp500406
12G.S3.06 succinate_on_gp1000607
13G.S3.07 succinate_on_gp00405
14G.s3h2.03 succinate_on_gp1000409
15G.H2.02 succinate_on_gp1000409
16G.H2.04 succinate_on_gp500509
17G.H2.06 succinate_on_gp1000808
18G.H2.07 succinate_on_gp1000709
19G.H2.09 succinate_on_gp500408
20G.H2.10 succinate_on_gp500408
21G.h2s4.01 succinate_on_gp1000507
22G.S4.02 succinate_on_gp500408
23G.S4.03 succinate_on_gp1000408
24G.S4.04 succinate_on_gp500407
25G.S4.05 succinate_on_gp1000409
26G.s4h3.04 succinate_on_gp1000508
27G.H3.01 succinate_on_gp00409
28G.H3.02 succinate_on_gp500409
29G.H3.09 succinate_on_gp1000709
30G.H3.13 succinate_on_gp500408
31G.H3.14 succinate_on_gp500405
32G.H3.17 succinate_on_gp1000604
33G.S5.03 succinate_on_gp1000406
34G.S5.04 succinate_on_gp500608
35G.S5.05 succinate_on_gp1000709
36G.S5.06 succinate_on_gp500409
37G.S5.07 succinate_on_gp1000408
38G.HG.04 succinate_on_gp500506
39G.HG.15 succinate_on_gp1000505
40G.hgh4.02 succinate_on_gp1000706
41G.hgh4.05 succinate_on_gp1000406
42G.H4.03 succinate_on_gp500405
43G.H4.10 succinate_on_gp500503
44G.H4.11 succinate_on_gp500406
45G.H4.15 succinate_on_gp1000505
46G.h4s6.02 succinate_on_gp1000404
47G.S6.02 succinate_on_gp1000605
48G.S6.03 succinate_on_gp500407
49G.s6h5.01 succinate_on_gp500404
50G.H5.03 succinate_on_gp00404
51G.H5.05 succinate_on_gp500407
52G.H5.08 succinate_on_gp1000708
53G.H5.17 succinate_on_gp1000406
54G.H5.26 succinate_on_gp500407
55b.1x4 succinate_on_gp00408
56b.1x19 succinate_on_gp500406
57b.lhb1x3 succinate_on_gp500402
58b.lhb1x6 succinate_on_gp500403
59b.lhb1x9 succinate_on_gp1000403
60b.b1x3 succinate_on_gp1000407
61b.b1x6 succinate_on_gp500409
62b.l1x3 succinate_on_gp1000609
63b.b2x1 succinate_on_gp1000508
64b.b2x3 succinate_on_gp1000406
65b.b2x5 succinate_on_gp1000707
66b.b3x2 succinate_on_gp500405
67b.l3x2 succinate_on_gp1000409
68b.b4x2 succinate_on_gp1000408
69b.b4x3 succinate_on_gp500407
70b.b4x4 succinate_on_gp1000408
71b.b4x6 succinate_on_gp1000709
72b.b5x2 succinate_on_gp00407
73b.b5x3 succinate_on_gp1000609
74b.b5x5 succinate_on_gp00405
75b.b5x7 succinate_on_gp1000407
76b.l5x1 succinate_on_gp1000408
77b.l5x5 succinate_on_gp1000709
78b.b6x5 succinate_on_gp500406
79b.l6x5 succinate_on_gp1000404
80b.b7x1 succinate_on_gp1000504
81b.b7x2 succinate_on_gp500408
82b.b7x4 succinate_on_gp1000408
83b.l7x4 succinate_on_gp1000409
84b.b8x3 succinate_on_gp1000506
85b.b8x4 succinate_on_gp1000706
86b.l8x8 succinate_on_gp1000404
87b.l9x3 succinate_on_gp1000609
88b.l9x6 succinate_on_gp1000908
89b.b10x5 succinate_on_gp500609
90b.b11x1 succinate_on_gp500405
91b.b11x2 succinate_on_gp1000407
92b.b11x4 succinate_on_gp1000609
93b.l11x2 succinate_on_gp1000409
94b.b12x3 succinate_on_gp1000408
95b.b12x5 succinate_on_gp500406
96b.b12x6 succinate_on_gp1000608
97b.b13x7 succinate_on_gp1000507
98b.l13x3 succinate_on_gp1000609
99b.l13x6 succinate_on_gp1000409
100b.l13x7 succinate_on_gp1000409
101b.b14x1 succinate_on_gp500408
102b.b14x3 succinate_on_gp1000405
103b.b15x1 succinate_on_gp1000509
104b.b15x3 succinate_on_gp1000409
105b.l15x1 succinate_on_gp1000407
106b.l15x2 succinate_on_gp1000509
107b.b16x4 succinate_on_gp1000406
108b.b16x5 succinate_on_gp500405
109b.b16x6 succinate_on_gp1000608
110b.b17x5 succinate_on_gp1000507
111b.b17x7 succinate_on_gp500408
112b.l17x3 succinate_on_gp1000609
113b.l17x6 succinate_on_gp1000509
114b.b18x3 succinate_on_gp1000408
115b.b18x5 succinate_on_gp500405
116b.l18x1 succinate_on_gp1000506
117b.l18x2 succinate_on_gp1000407
118b.b19x2 succinate_on_gp1000606
119b.b19x4 succinate_on_gp1000408
120b.l19x1 succinate_on_gp500409
121b.l19x2 succinate_on_gp1000509
122b.b20x2 succinate_on_gp1000406
123b.b20x4 succinate_on_gp1000708
124b.b20x6 succinate_on_gp1000606
125b.b21x1 succinate_on_gp500507
126b.b21x5 succinate_on_gp00404
127b.b21x7 succinate_on_gp1000505
128b.b22x5 succinate_on_gp500407
129b.l22x5 succinate_on_gp1000609
130b.b23x2 succinate_on_gp500406
131b.b23x6 succinate_on_gp1000707
132b.l23x1 succinate_on_gp1000406
133b.b24x4 succinate_on_gp1000506
134b.b24x6 succinate_on_gp500408
135b.b25x3 succinate_on_gp00505
136b.b25x6 succinate_on_gp00503
137b.l25x3 succinate_on_gp1000509
138b.b26x3 succinate_on_gp500406
139b.l27x1 succinate_on_gp1000709
140b.l27x2 succinate_on_gp1000409
141b.b28x3 succinate_on_gp1000407
142b.b28x4 succinate_on_gp1000406
143b.b28x6 succinate_on_gp1000509
144g.h1x3 succinate_on_gp00403
145g.l1x4 succinate_on_gp500508
146g.h2x11 succinate_on_gp1000406
147g.ctx3 succinate_on_gp1000609
148g.ctx6 succinate_on_gp500506
149g.ctx14 succinate_on_gp1000509
150g.ctx15 succinate_on_gp1000409
151g.ctx16 succinate_on_gp1000708
1521x27 succinate_on_gp500525
1531x34 succinate_on_gp1000434
1541x38 succinate_on_gp00435
1551x42 succinate_on_gp500437
1562x41 succinate_on_gp1000527
1572x46 succinate_on_gp500419
1582x49 succinate_on_gp500428
1592x50 succinate_on_gp1000439
1602x51 succinate_on_gp00428
1613x30 succinate_on_gp500536
1623x32 succinate_on_gp1000527
1633x33 succinate_on_gp500435
1643x35 succinate_on_gp500538
1653x45 succinate_on_gp500426
1663x50 succinate_on_gp1000529
1674x45 succinate_on_gp500535
1684x49 succinate_on_gp500427
1694x50 succinate_on_gp1000439
1704x57 succinate_on_gp1000427
1714x61 succinate_on_gp1000624
172E2x52 succinate_on_gp500535
1735x35 succinate_on_gp00422
1745x39 succinate_on_gp1000535
1755x44 succinate_on_gp500426
1765x50 succinate_on_gp1000428
1775x51 succinate_on_gp500436
1785x54 succinate_on_gp1000428
1795x58 succinate_on_gp1000639
180I3 succinate_on_gp1000704
1816x33 succinate_on_gp500537
1826x34 succinate_on_gp00426
1836x54 succinate_on_gp500434
1846x58 succinate_on_gp500435
1857x39 succinate_on_gp10050435
1867x43 succinate_on_gp500435
1877x47 succinate_on_gp500428
1887x49 succinate_on_gp10050539
1897x54 succinate_on_gp1000626
190Lig Shared1001009110
1911x23 Shared00445
1921x39 Shared100100758
1931x50 Shared500449
1941x57 Shared100100567
1952x42 Shared100100447
1962x53 Shared100100557
1972x64 Shared100100545
198E1x50 Shared100100558
199E1x52 Shared100100447
2003x29 Shared5050446
2013x37 Shared100100557
2023x42 Shared100100458
2033x51 Shared50100448
2043x56 Shared1000546
205I2x52 Shared50100545
206I2x57 Shared100100547
207E2 Shared10010011164
2085x47 Shared1000658
2096x44 Shared100100549
2106x48 Shared100100668
2116x51 Shared100100657
2126x52 Shared100100668
2136x55 Shared100100776
2147x34 Shared100100655
2157x38 Shared100100546
2167x42 Shared10050547
2177x52 Shared1000447
2187x53 Shared100100559
2192x44 succinate_off0100356
2203x36 succinate_off0100348
2213x38 succinate_off050347
2223x54 succinate_off00148
2234x41 succinate_off00344
224E2x50 succinate_off050249
2255x43 succinate_off0100345
2265x61 succinate_off500258
2277x45 succinate_off0100349
2288x50 succinate_off0100268
   
Orange: nodes, hubs and links specific of succinate_on_gp network

Green: nodes, hubs and links shared by both networks

Purple: nodes, hubs and links specific of succinate_off network

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Owner: the name of the network the link belong to or "Shared" if the corresponding link is present in both networks.

Recurrence: the relative Recurrence in the filtered pool of shortest paths.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.


Index Node1 Node2 Owner succinate_on_gp Recurrence succinate_off Recurrence succinate_on_gp Hub1? succinate_off Hub1? succinate_on_gp Hub2? succinate_off Hub2? ConSurf1 ConSurf2
1b.b10x1 b.b11x5 succinate_on_gp17.3520NoNoNoNo96
2b.b10x1 b.l9x6 succinate_on_gp17.36350NoNoYesNo98
3G.H2.07 b.l9x6 succinate_on_gp63.77190YesNoYesNo98
4G.H2.04 G.H2.07 succinate_on_gp94.03930YesNoYesNo99
5G.H2.04 G.H3.08 succinate_on_gp94.19240YesNoNoNo95
6G.H3.08 G.S4.04 succinate_on_gp94.22620NoNoYesNo57
7G.S4.04 G.s1h1.01 succinate_on_gp99.97190YesNoNoNo79
8G.s1h1.01 G.s1h1.05 succinate_on_gp1000NoNoYesNo99
9G.S4.05 G.s1h1.05 succinate_on_gp97.590YesNoYesNo99
10G.H1.04 G.S4.05 succinate_on_gp49.00850YesNoYesNo99
11G.H1.04 G.S5.05 succinate_on_gp48.8890YesNoYesNo99
12G.S4.05 G.S5.07 succinate_on_gp48.89450YesNoYesNo98
13G.S5.05 G.S5.07 succinate_on_gp48.77930YesNoYesNo98
14G.H2.07 G.h2s4.01 succinate_on_gp15.30410YesNoYesNo97
15G.H2.07 b.l7x2 succinate_on_gp14.58850YesNoNoNo99
16G.h2s4.01 b.l5x5 succinate_on_gp14.50820YesNoYesNo79
17b.l5x5 b.l7x2 succinate_on_gp14.4630YesNoNoNo99
18G.H2.09 G.H3.17 succinate_on_gp14.29120YesNoYesNo84
19G.H3.17 b.l25x6 succinate_on_gp14.0090YesNoNoNo48
20b.l23x1 b.l25x6 succinate_on_gp69.00430YesNoNoNo68
21b.b22x1 b.l23x1 succinate_on_gp42.41950NoNoYesNo86
22b.b22x1 b.b22x2 succinate_on_gp42.11460NoNoNoNo88
23b.b22x2 b.b26x3 succinate_on_gp41.80980NoNoYesNo86
24b.b22x4 b.b26x3 succinate_on_gp10.27070NoNoYesNo56
25b.b27x1 g.ctx5 succinate_on_gp18.71330NoNoNoNo69
26g.ctx3 g.ctx5 succinate_on_gp27.24030YesNoNoNo99
27g.ctx3 g.ctx4 succinate_on_gp19.5090YesNoNoNo97
28b.l26x5 g.ctx4 succinate_on_gp14.95660NoNoNoNo57
29b.l26x5 g.ctx15 succinate_on_gp11.00590NoNoYesNo59
30G.H2.09 b.l27x1 succinate_on_gp14.22570YesNoYesNo89
31b.l25x6 b.l27x1 succinate_on_gp55.29580NoNoYesNo89
32b.b24x3 b.b26x3 succinate_on_gp25.37450NoNoYesNo56
33b.b23x3 b.b24x3 succinate_on_gp10.87860NoNoNoNo75
34b.b24x3 b.b25x7 succinate_on_gp14.19440NoNoNoNo57
35b.b25x7 b.lhb1x11 succinate_on_gp13.97830NoNoNoNo74
36G.H2.10 b.b6x1 succinate_on_gp43.10170YesNoNoNo89
37b.b6x1 b.l9x6 succinate_on_gp43.20640NoNoYesNo98
38b.b2x1 b.l27x1 succinate_on_gp42.01920YesNoYesNo89
39b.b2x1 b.l3x1 succinate_on_gp28.27170YesNoNoNo89
40G.S5.03 G.S5.05 succinate_on_gp90.86730YesNoYesNo69
41G.H5.10 G.S5.03 succinate_on_gp91.02210NoNoYesNo46
42G.H5.10 G.S6.02 succinate_on_gp90.98970NoNoYesNo45
43G.S6.02 G.h4s6.12 succinate_on_gp45.62470YesNoNoNo57
44G.H5.17 G.h4s6.12 succinate_on_gp45.34840YesNoNoNo67
45G.H5.13 G.H5.17 succinate_on_gp45.34850NoNoYesNo66
46G.H5.13 G.S6.02 succinate_on_gp45.39320NoNoYesNo65
47G.H5.17 G.H5.26 succinate_on_gp90.64670YesNoYesNo67
48G.H5.20 G.H5.26 succinate_on_gp81.45180NoNoYesNo87
49G.H5.20 G.H5.25 succinate_on_gp81.38530NoNoNoNo88
503x50 G.H5.25 succinate_on_gp55.72950YesNoNoNo98
513x50 7x53 succinate_on_gp25.67530YesNoYesYes99
526x37 G.H5.25 succinate_on_gp25.6670NoNoNoNo88
53b.b21x7 b.b24x6 succinate_on_gp15.61140YesNoYesNo58
54b.b23x6 b.b24x6 succinate_on_gp17.01810YesNoYesNo78
55b.l21x7 b.l23x1 succinate_on_gp26.14720NoNoYesNo56
567x49 7x53 succinate_on_gp22.68990YesNoYesYes99
575x47 6x52 succinate_on_gp19.41833.50221YesYesYesYes88
585x47 6x44 succinate_on_gp21.47850YesYesYesYes89
595x54 6x44 succinate_on_gp44.61640YesNoYesYes89
605x54 5x58 succinate_on_gp46.19860YesNoYesNo89
613x50 5x58 succinate_on_gp23.51170YesNoYesNo99
625x58 6x37 succinate_on_gp23.7080YesNoNoNo98
63G.H2.09 G.H2.10 succinate_on_gp28.56980YesNoYesNo88
64G.H2.10 b.b2x1 succinate_on_gp14.47610YesNoYesNo88
65b.l3x1 b.l5x5 succinate_on_gp28.38780NoNoYesNo99
66b.b23x6 b.l21x7 succinate_on_gp23.69790YesNoNoNo75
672x50 7x49 Shared11.237162.694YesNoYesNo99
686x55 E2 Shared21.38626.8758YesYesYesYes64
696x52 6x55 Shared30.029732.7463YesYesYesYes86
706x48 6x52 Shared29.158347.6196YesYesYesYes88
716x48 7x45 Shared11.015853.1403YesYesNoYes89
727x45 7x49 Shared11.369763.1122NoYesYesNo99
736x51 6x52 Shared11.049710.6353YesYesYesYes78
746x44 6x48 Shared21.997819.4129YesYesYesYes98
75E1x50 Lig succinate_off017.7282YesYesYesYes80
761x23 7x28 succinate_off012.8629YesYesNoNo52
771x27 7x28 succinate_off0.51973419.1998YesNoNoNo52
781x27 7x31 succinate_off020.8565YesNoNoNo53
796x58 7x31 succinate_off1.7417422.7624YesNoNoNo53
806x58 7x34 succinate_off6.940115.6092YesNoYesYes55
817x34 7x38 succinate_off0.044831417.5191YesYesYesYes56
827x38 Lig succinate_off0.039979618.2147YesYesYesYes60
831x39 Lig succinate_off0.05014612.0466YesYesYesYes80
841x39 7x39 succinate_off0.89104113.1765YesYesYesNo85
857x42 Lig succinate_off3.7469734.4712YesYesYesYes70
862x53 7x42 succinate_off2.8510345.2312YesYesYesYes77
872x53 2x54 succinate_off010.8524YesYesNoNo76
882x53 7x46 succinate_off8.420337.2095YesYesNoNo79
892x50 7x46 succinate_off9.8181841.9984YesNoNoNo99
901x50 2x50 succinate_off1.55253100YesYesYesNo99
911x50 2x47 succinate_off0.077150294.0893YesYesNoNo99
922x47 7x53 succinate_off093.1202NoNoYesYes99
931x57 7x53 succinate_off074.2019YesYesYesYes79
947x53 8x50 succinate_off016.2686YesYesNoYes98
951x57 2x40 succinate_off068.7455YesYesNoNo77
962x37 2x40 succinate_off0.15524268.8138NoNoNoNo77
972x37 I2x52 succinate_off0.2912261.1178NoNoYesYes75
983x36 7x42 succinate_off036.1319NoYesYesYes87
993x36 6x48 succinate_off3.5336826.3731NoYesYesYes88
1003x43 6x44 succinate_off028.0177NoNoYesYes89
1013x43 7x52 succinate_off025.5368NoNoYesYes87
1026x36 7x52 succinate_off7.9062820.5871NoNoYesYes87
1033x46 6x36 succinate_off018.1825NoNoNoNo98
1042x42 3x46 succinate_off016.8838YesYesNoNo79
1052x53 3x35 succinate_off0.18615610.9208YesYesYesNo78
1062x49 3x35 succinate_off2.5483714.6723YesNoYesNo88
1072x49 3x38 succinate_off0.24155313.2409YesNoNoYes87
108E1x50 E1x52 succinate_off010.5629YesYesYesYes87
1093x36 3x37 succinate_off3.1500515.4564NoYesYesYes87
1103x36 6x51 succinate_off023.8641NoYesYesYes87
1116x55 7x34 succinate_off5.7926812.7986YesYesYesYes65
112I2x52 I2x57 succinate_off2.744757.4548YesYesYesYes57
1133x56 I2x57 succinate_off3.1780653.6751YesYesYesYes67
1143x55 3x56 succinate_off2.8657348.8983NoNoYesYes76
1153x51 3x55 succinate_off2.736134.5195YesYesNoNo87
1163x51 5x61 succinate_off2.2795523.8721YesYesNoYes88
1173x55 5x64 succinate_off013.3092NoNoNoNo75
1183x37 5x43 succinate_off6.483614.9618YesYesNoYes75
1194x60 5x39 succinate_off1.5126215.8665NoNoYesNo85
1206x51 7x37 succinate_off2.8992332.887YesYesNoNo77
1216x54 7x37 succinate_off1.7341930.2493YesNoNoNo47
1226x54 6x57 succinate_off1.7388326.2686YesNoNoNo45
1236x57 7x30 succinate_off024.2622NoNoNoNo55
1246x61 7x30 succinate_off3.4747720.6152NoNoNoNo25
1256x61 7x27 succinate_off1.7373918.5887NoNoNoNo23
1266x62 7x27 succinate_off016.5581NoNoNoNo33
1275x33 6x62 succinate_off0.58389314.5195NoNoNoNo13
1285x32 5x33 succinate_off1.1676710.4101NoNoNoNo31
1295x61 6x34 succinate_off010.4664NoYesYesNo86
1304x59 4x60 succinate_off013.2167NoNoNoNo48
1315x39 5x43 succinate_off3.7120312.8589YesNoNoYes55
1326x44 7x45 succinate_off010.965YesYesNoYes99

Here, those paths that begin and end at given residue pair(s) or that pass through a residue are used to generate a novel metapath. Such a path filtering is particularly recommended if some information on allosteric residues is available. The selection syntax for a residue pair ("Pairs") is C:C:c534,A:A:?600 (the lower-case "c" stands for cytosine and "?" indicates any non standard amino acid or nucleotide residue). Selection of more than one apical residue pair has the following syntax: C:C:c534,A:A:?600,C:C:c534,A:A:E41. Only one residue can be selected as a tail ("Tail"). For midway residue(s), each residue must be separated by a comma as well e.g. A:A:?600,A:A:E41.

Midway



Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.


2D representation of the interactions of this orthosteric/allosteric ligand.


Node1Node2OwnerNet1LinkStrengthNet2LinkStrengthComm1Comm2Node1ShellNode2Shell
1x31Ligsuccinate_off5.201010
1x39LigShared6.67510.1750110
2x60LigShared10.6256.010110
2x64LigShared17.4358.541110
E1x50Ligsuccinate_off10.16501010
3x29LigShared27.397.081110
3x32LigShared11.9955.3551110
E2x50Ligsuccinate_off4.7201010
7x38LigShared13.85525.161110
7x42LigShared4.5355.831110
1x312x64Shared11.7858.421011
1x351x39Shared4.6912.8950021
1x352x64Shared10.557.0350021
1x392x57Shared7.035.2750112
1x397x39Shared11.139.040112
2x532x57succinate_off9.7401122
2x537x42Shared1513.931121
2x563x28Shared5.857.3150022
2x59E1x52Shared16.769.581022
2x593x28Shared9.11515.431022
2x63E1x50Shared4.949.2650021
2x647x38succinate_off5.1401111
E1x50E1x52succinate_off12.5401012
3x28E1x50succinate_off4.5200021
E1x50E2x50Shared9.147.1851011
3x25E2x50succinate_off7.2800021
3x29E2x50Shared7.663.4851111
3x29E2x52Shared5.963.5751111
3x327x42Shared7.313.6551111
3x334x57succinate_off6.9201112
3x334x61Shared11.1653.981112
3x33E2Shared8.7110.181112
3x366x51succinate_off4.6900022
3x367x42succinate_off9.13500021
4x61E2Shared7.1810.0451122
E2E2succinate_off20.30501122
E2E2x52Shared11.514.451121
7x34E2x52succinate_off8.0501121
7x34E2Shared5.275.341122
7x347x38Shared13.8918.521121
7x357x38succinate_off5.63500021
3x294x65Shared4.3855.641112
1x392x61Shared2.423.630112
3x21E2succinate_off2.1100022
2x67Ligsuccinate_off0.4200010
3x33Ligsuccinate_on_gp07.461110
E2x52Ligsuccinate_on_gp08.351110
1x357x35succinate_on_gp03.570022
1x397x38succinate_on_gp05.140111
1x397x42succinate_on_gp08.7650111
1x427x39succinate_on_gp03.140122
1x427x42succinate_on_gp04.080121
2x533x32succinate_on_gp07.9151121
2x533x36succinate_on_gp04.871122
2x563x32succinate_on_gp06.6350021
2x59E1x50succinate_on_gp06.41021
2x602x64succinate_on_gp03.5150111
2x603x28succinate_on_gp04.120112
2x64E2x52succinate_on_gp03.451111
3x25E1x50succinate_on_gp07.840021
3x323x33succinate_on_gp04.51111
4x574x61succinate_on_gp05.710122
4x614x65succinate_on_gp05.891122
7x38E2x52succinate_on_gp05.9551111
6x517x34succinate_on_gp08.9351122
6x517x38succinate_on_gp03.6051121
3x21E1x50succinate_on_gp02.110021

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Difference Members
Id Description
succinate_on_gp 8YKW-Succinate-Succinic acid-Gi1/β1/γ1
8YKX-Succinate-Maleic acid-Gi1/β1/γ1
succinate_off 6RNK-Succinate-NF-56-EJ40
6Z10-Succinate-PubChem 154585554
Network Difference
Value succinate_on_gp succinate_off
Imin 2.9 4.46
Number of Linked Nodes 861 265
Number of Specific Nodes 605 (70.27%) 9  (3.40%)
Number of Shared Nodes 256 (29.73%) 256  (96.60%)
Number of Links 1137 308
Number of Specific Links 953 (83.82%) 124  (40.26%)
Number of Shared Links 184 (16.18%) 184  (59.74%)
Number of Hubs 218 39
Number of Specific Hubs 189 (86.70%) 10  (25.64%)
Number of Shared Hubs 29 (13.30%) 29  (74.36%)
Average % Shared Neighbours (Jaccard) 12.46
Average % Shared Neighbours (Otsuka) 15.67
Average % Shared Neighbours (Overlap Coefficient) 18.86
Average % Shared Cliques (k3-6) 51.49
Graphlets Similarity 0.704726
Paths Difference
Value succinate_on_gp succinate_off
Number Of Nodes in MetaPath 67 63
Specific Nodes in MetaPath 57 (85.07%) 53  (84.13%)
Shared Nodes in MetaPath 256 (29.73%) 256  (29.73%)
Number Of Links MetaPath 74 66
Specific Links in MetaPath 66 (89.19%) 58  (87.88%)
Shared Links in MetaPath 184 (16.18%) 184  (16.18%)
Number of Shortest Paths 6995217 52483
Length Of Smallest Path 3 3
Average Path Length 36.1808 14.1198
Length of Longest Path 54 36
Minimum Path Strength 0.6175 1.27
Average Path Strength 6.74807 8.21559
Maximum Path Strength 27.09 22.4125
Minimum Path Correlation 0.705 0.7
Average Path Correlation 0.996468 0.91028
Maximum Path Correlation 1 0.99
Minimum % Of Corr. Nodes 2.04082 3.84615
Average % Of Corr. Nodes 35.619 42.3904
Maximum % Of Corr. Nodes 100 100
Minimum Path Hubs % 0 0
Average Path Hubs % 61.7756 46.9527
Maximum Path Hubs % 100 100

Details about the values in these tables can be found in the corresponding documentation page .

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