Code140
NameN-hexadecanoylglycine
SynonymsN-hexadecanoylglycine
Identifier2-(hexadecanoylamino)ethanoic acid
FormulaC18 H35 N O3
Molecular Weight313.475
SMILESCCCCCCCCCCCCCCCC(=O)NCC(=O)O
PubChem151008
Formal Charge0
Total Atoms57
Total Chiral Atoms0
Total Bonds56
Total Aromatic Bonds0
Networks1
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This ligand is also present in the following network:
Show PDB Class SubFamily Type SubType Species Orthosteric Ligand Other Ligand(s) Protein Partners Resolution Date DOI
8HQM A Orphan A orphans GPR132 Homo Sapiens NPGLY - Gi1/Beta1/Gamma2 2.95 2023-10-11 0.1038/s42255-023-00899-4

A 2D representation of the interactions of 140 in 8HQM
colored according to ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

(Click to enlarge 🔍)
Node1 Node2 LinkStrength Comm IsNode1Hub? IsNode2Hub? Node1Cons Node2Cons Node1Shell Node2Shell
R:R:F38 R:R:R42 5.34 4 Yes Yes 2 4 2 2
R:R:F38 R:R:H106 5.66 4 Yes Yes 2 5 2 1
R:R:F38 R:R:Y287 5.16 4 Yes Yes 2 4 2 1
R:R:H106 R:R:R42 16.93 4 Yes Yes 5 4 1 2
R:R:F187 R:R:R42 3.21 4 Yes Yes 4 4 2 2
R:R:R42 R:R:Y287 6.17 4 Yes Yes 4 4 2 1
R:R:F187 R:R:H106 4.53 4 Yes Yes 4 5 2 1
R:R:H106 R:R:Y287 8.71 4 Yes Yes 5 4 1 1
L:L:?1 R:R:H106 17.2 4 Yes Yes 0 5 0 1
L:L:?1 R:R:E184 7.88 4 Yes No 0 4 0 1
R:R:F187 R:R:T185 6.49 4 Yes No 4 3 2 1
R:R:M189 R:R:T185 3.01 0 Yes No 4 3 2 1
L:L:?1 R:R:T185 10.95 4 Yes No 0 3 0 1
R:R:F187 R:R:Y287 6.19 4 Yes Yes 4 4 2 1
R:R:D188 R:R:L190 16.29 4 Yes Yes 5 4 1 2
R:R:D188 R:R:Y200 11.49 4 Yes Yes 5 5 1 2
R:R:D188 R:R:K265 6.91 4 Yes Yes 5 5 1 2
L:L:?1 R:R:D188 5.04 4 Yes Yes 0 5 0 1
R:R:M189 R:R:Q191 2.72 0 Yes No 4 4 2 1
R:R:L190 R:R:Y200 8.21 4 Yes Yes 4 5 2 2
R:R:K265 R:R:L190 2.82 4 Yes Yes 5 4 2 2
R:R:F269 R:R:Q191 4.68 0 No No 4 4 2 1
L:L:?1 R:R:Q191 23.74 4 Yes No 0 4 0 1
R:R:K265 R:R:S290 3.06 4 Yes No 5 5 2 2
R:R:E283 R:R:F269 4.66 0 Yes No 3 4 1 2
R:R:E283 R:R:M279 10.83 0 Yes No 3 4 1 2
R:R:C280 R:R:E283 3.04 0 No Yes 8 3 2 1
L:L:?1 R:R:E283 10.83 4 Yes Yes 0 3 0 1
R:R:S290 R:R:Y287 5.09 0 No Yes 5 4 2 1
R:R:V291 R:R:Y287 3.79 0 No Yes 4 4 2 1
L:L:?1 R:R:Y287 19.16 4 Yes Yes 0 4 0 1
StatisticsValue
Average Number Of Links7.00
Average Number Of Links With An Hub4.00
Average Interaction Strength13.54
Average Nodes In Shell20.00
Average Hubs In Shell12.00
Average Links In Shell31.00
Average Links Mediated by Hubs In Shell30.00
Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)
Location of the nodes interacting with this ligand (click to enlarge 🔍)
StatisticsValue
Average Number Of Links7.00
Average Number Of Links With An Hub4.00
Average Interaction Strength13.54
Average Nodes In Shell20.00
Average Hubs In Shell12.00
Average Links In Shell31.00
Average Links Mediated by Hubs In Shell30.00

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Physico-chemical properties of the nodes interacting with this ligand

(Click to enlarge 🔍)

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Location of the nodes interacting with this ligand

(Click to enlarge 🔍)