Code18C
NameN-((E,2S,3R)-1,3-DIHYDROXYOCTADEC-4-EN-2-YL)STEARAMIDE
SynonymsC18-CERAMIDE; N-STEAROYL-D-ERYTHRO-SPHINGOSINE; (2S,3R,4E)-2-STEAROYLAMINOOCTADEC-4-ENE-1,3-DIOL; (2S,3R,4E)-2-STEAROYLAMINO-1,3-OCTADEC-4-ENEDIOL
Identifier
FormulaC36 H71 N O3
Molecular Weight565.954
SMILES
PubChem5283565
Formal Charge0
Total Atoms111
Total Chiral Atoms2
Total Bonds110
Total Aromatic Bonds0
Networks2
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This ligand is also present in the following 2 networks:
Show PDB Class SubFamily Type SubType Species Orthosteric Ligand Other Ligand(s) Protein Partners Resolution Date DOI
9JHJ A Peptide Formylpeptide FPR2-ALX Homo Sapiens C18:0 Ceramide - Gi1/Beta1/Gamma2 3.2 2025-03-19 doi.org/10.1126/science.ado4188

A 2D representation of the interactions of 18C in 9JHJ
colored according to ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

(Click to enlarge 🔍)
Node1 Node2 LinkStrength Comm IsNode1Hub? IsNode2Hub? Node1Cons Node2Cons Node1Shell Node2Shell
L:L:?1 R:R:E89 8.68 2 Yes No 0 4 0 1
L:L:?1 R:R:D106 4.04 2 Yes No 0 5 0 1
L:L:?1 R:R:F110 2.9 2 Yes Yes 0 7 0 1
L:L:?1 R:R:V167 1.78 2 Yes No 0 1 0 1
L:L:?1 R:R:P170 2.94 2 Yes No 0 3 0 1
L:L:?1 R:R:Y175 14.67 2 Yes Yes 0 3 0 1
L:L:?1 R:R:T177 7.03 2 Yes No 0 3 0 1
L:L:?1 R:R:N179 8.18 2 Yes No 0 3 0 1
L:L:?1 R:R:R201 5.79 2 Yes Yes 0 5 0 1
L:L:?1 R:R:R205 9.41 2 Yes Yes 0 5 0 1
R:R:D106 R:R:F110 14.33 2 No Yes 5 7 1 1
R:R:D106 R:R:T157 8.67 2 No No 5 7 1 2
R:R:F110 R:R:F114 2.14 2 Yes Yes 7 6 1 2
R:R:F110 R:R:L156 8.53 2 Yes No 7 5 1 2
R:R:I169 R:R:P170 3.39 0 No No 1 3 2 1
R:R:I169 R:R:Y175 12.09 0 No Yes 1 3 2 1
R:R:D173 R:R:Y175 3.45 0 No Yes 3 3 2 1
R:R:T177 R:R:Y175 8.74 2 No Yes 3 3 1 1
R:R:F178 R:R:R201 4.28 0 No Yes 4 5 2 1
R:R:G202 R:R:R201 3 0 No Yes 4 5 2 1
R:R:R201 R:R:R205 2.13 2 Yes Yes 5 5 1 1
R:R:Q258 R:R:R205 4.67 2 Yes Yes 8 5 2 1
R:R:A261 R:R:R205 4.15 0 No Yes 5 5 2 1
R:R:E89 R:R:G88 1.64 0 No No 4 3 1 2
R:R:T165 R:R:V167 1.59 0 No No 4 1 2 1
R:R:A181 R:R:N179 1.56 0 No No 5 3 2 1
StatisticsValue
Average Number Of Links10.00
Average Number Of Links With An Hub4.00
Average Interaction Strength6.54
Average Nodes In Shell23.00
Average Hubs In Shell7.00
Average Links In Shell26.00
Average Links Mediated by Hubs In Shell21.00
Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)
Location of the nodes interacting with this ligand (click to enlarge 🔍)
StatisticsValue
Average Number Of Links10.00
Average Number Of Links With An Hub2.50
Average Interaction Strength6.54
Average Nodes In Shell22.50
Average Hubs In Shell5.00
Average Links In Shell25.00
Average Links Mediated by Hubs In Shell17.50

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Physico-chemical properties of the nodes interacting with this ligand

(Click to enlarge 🔍)

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Location of the nodes interacting with this ligand

(Click to enlarge 🔍)