Code2OP
NameL-Lactic acid
Synonyms(S)-(+)-lactic acid
Identifier
FormulaC3 H6 O3
Molecular Weight90.078
SMILES
PubChem107689
Formal Charge0
Total Atoms12
Total Chiral Atoms1
Total Bonds11
Total Aromatic Bonds0
Networks2
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This ligand is also present in the following 2 networks:
Show PDB Class SubFamily Type SubType Species Orthosteric Ligand Other Ligand(s) Protein Partners Resolution Date DOI
8Z8A A Alicarboxylic acid Hydroxycarboxylic Acid HCA1 Homo Sapiens Lactate - Gi1/Beta1/Gamma2 2.82 2025-10-29 To be published

A 2D representation of the interactions of 2OP in 8Z8A
colored according to ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

(Click to enlarge 🔍)
Node1 Node2 LinkStrength Comm IsNode1Hub? IsNode2Hub? Node1Cons Node2Cons Node1Shell Node2Shell
L:L:?1 R:R:R71 9.74 7 Yes Yes 0 6 0 1
L:L:?1 R:R:L95 8.32 7 Yes No 0 6 0 1
L:L:?1 R:R:R99 4.87 7 Yes No 0 8 0 1
L:L:?1 R:R:S167 6.02 7 Yes No 0 4 0 1
L:L:?1 R:R:L264 4.16 7 Yes Yes 0 6 0 1
L:L:?1 R:R:Y268 10.58 7 Yes Yes 0 7 0 1
R:R:L64 R:R:Y268 7.03 0 Yes Yes 7 7 2 1
R:R:C67 R:R:L95 3.17 0 No No 6 6 2 1
R:R:L68 R:R:Y268 4.69 0 No Yes 8 7 2 1
R:R:R71 R:R:Y74 8.23 7 Yes Yes 6 5 1 2
R:R:R71 R:R:Y75 5.14 7 Yes Yes 6 5 1 2
R:R:Y74 R:R:Y75 7.94 7 Yes Yes 5 5 2 2
R:R:L92 R:R:S167 4.5 7 Yes No 6 4 2 1
R:R:E184 R:R:R99 4.65 0 No No 5 8 2 1
R:R:R99 R:R:Y268 3.09 7 No Yes 8 7 1 1
R:R:F168 R:R:S167 3.96 8 Yes No 4 4 2 1
R:R:F168 R:R:L264 6.09 8 Yes Yes 4 6 2 1
R:R:L264 R:R:S236 3 0 Yes No 6 6 1 2
R:R:T267 R:R:Y268 6.24 0 No Yes 8 7 2 1
R:R:L260 R:R:L264 2.77 0 No Yes 4 6 2 1
R:R:L22 R:R:R71 2.43 0 No Yes 7 6 2 1
StatisticsValue
Average Number Of Links6.00
Average Number Of Links With An Hub3.00
Average Interaction Strength7.28
Average Nodes In Shell19.00
Average Hubs In Shell9.00
Average Links In Shell21.00
Average Links Mediated by Hubs In Shell19.00
Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)
Location of the nodes interacting with this ligand (click to enlarge 🔍)
StatisticsValue
Average Number Of Links6.00
Average Number Of Links With An Hub2.50
Average Interaction Strength7.28
Average Nodes In Shell18.00
Average Hubs In Shell8.00
Average Links In Shell19.50
Average Links Mediated by Hubs In Shell17.00

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Physico-chemical properties of the nodes interacting with this ligand

(Click to enlarge 🔍)

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Location of the nodes interacting with this ligand

(Click to enlarge 🔍)