Code4PH
Name4-methyl-L-phenylalanine
Synonyms
Identifier(2S)-2-azanyl-3-(4-methylphenyl)propanoic acid
FormulaC10 H13 N O2
Molecular Weight179.216
SMILESCc1ccc(cc1)C[C@@H](C(=O)O)N
PubChem151513
Formal Charge0
Total Atoms26
Total Chiral Atoms1
Total Bonds26
Total Aromatic Bonds6
Networks1
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This ligand is also present in the following network:
Show PDB Class SubFamily Type SubType Species Orthosteric Ligand Other Ligand(s) Protein Partners Resolution Date DOI
7WUI B2 Adhesion Adhesion ADGRG2 Mus musculus IP15 - chim(NtGi1-Gs)/Beta1/Gamma2 3.1 2022-04-27 10.1038/s41586-022-04590-8

A 2D representation of the interactions of 4PH in 7WUI
colored according to ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

(Click to enlarge 🔍)
Node1 Node2 LinkStrength Comm IsNode1Hub? IsNode2Hub? Node1Cons Node2Cons Node1Shell Node2Shell
L:L:S2 R:R:L620 9.01 0 Yes No 0 9 1 2
R:R:T624 R:R:T861 4.71 1 No Yes 9 8 1 1
L:L:?3 R:R:T624 13.48 1 Yes No 0 9 0 1
R:R:G627 R:R:T861 5.46 0 No Yes 9 8 2 1
R:R:C628 R:R:N668 6.3 0 No No 9 9 2 1
R:R:C628 R:R:T861 5.07 0 No Yes 9 8 2 1
R:R:N668 R:R:S631 4.47 0 No No 9 9 1 2
L:L:?3 R:R:N668 4.19 1 Yes No 0 9 0 1
R:R:F671 R:R:L693 8.53 0 No No 9 9 1 2
R:R:F671 R:R:F769 7.5 0 No Yes 9 9 1 2
L:L:?3 R:R:F671 10.21 1 Yes No 0 9 0 1
R:R:L693 R:R:W771 11.39 0 No Yes 9 9 2 2
R:R:F701 R:R:L697 10.96 1 Yes Yes 9 9 2 2
R:R:L697 R:R:W771 4.56 1 Yes Yes 9 9 2 2
L:L:L6 R:R:L697 12.46 1 No Yes 0 9 1 2
R:R:F701 R:R:F786 24.65 1 Yes No 9 9 2 2
R:R:F701 R:R:W838 8.02 1 Yes Yes 9 9 2 1
R:R:M704 R:R:W838 6.98 0 No Yes 9 9 2 1
R:R:F769 R:R:W771 5.01 1 Yes Yes 9 9 2 2
L:L:L6 R:R:W771 18.22 1 No Yes 0 9 1 2
R:R:F786 R:R:W838 5.01 1 No Yes 9 9 2 1
R:R:G835 R:R:W838 4.22 0 No Yes 9 9 2 1
R:R:F856 R:R:W838 5.01 1 Yes Yes 9 9 2 1
R:R:N860 R:R:W838 35.03 1 No Yes 9 9 2 1
R:R:Q863 R:R:W838 10.95 0 No Yes 9 9 2 1
L:L:?3 R:R:W838 6.94 1 Yes Yes 0 9 0 1
R:R:F856 R:R:N860 9.67 1 Yes No 9 9 2 2
R:R:L862 R:R:T861 4.42 1 No Yes 7 8 2 1
L:L:?3 R:R:T861 4.49 1 Yes Yes 0 8 0 1
L:L:?3 L:L:G4 6.52 1 Yes No 0 0 0 1
L:L:?3 L:L:L6 7.38 1 Yes No 0 0 0 1
L:L:?3 L:L:S2 3.43 1 Yes Yes 0 0 0 1
L:L:S2 R:R:M617 3.07 0 Yes No 0 4 1 2
L:L:?3 R:R:A857 2.4 1 Yes No 0 7 0 1
L:L:S2 R:R:T621 1.6 0 Yes No 0 9 1 2
StatisticsValue
Average Number Of Links9.00
Average Number Of Links With An Hub3.00
Average Interaction Strength6.56
Average Nodes In Shell28.00
Average Hubs In Shell9.00
Average Links In Shell35.00
Average Links Mediated by Hubs In Shell32.00
Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)
Location of the nodes interacting with this ligand (click to enlarge 🔍)
StatisticsValue
Average Number Of Links9.00
Average Number Of Links With An Hub3.00
Average Interaction Strength6.56
Average Nodes In Shell28.00
Average Hubs In Shell9.00
Average Links In Shell35.00
Average Links Mediated by Hubs In Shell32.00

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Physico-chemical properties of the nodes interacting with this ligand

(Click to enlarge 🔍)

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Location of the nodes interacting with this ligand

(Click to enlarge 🔍)