Code6MD
NameN-methyladenosine
Synonyms
Identifier
FormulaC11 H15 N5 O4
Molecular Weight281.268
SMILES
PubChem102175
Formal Charge0
Total Atoms35
Total Chiral Atoms4
Total Bonds37
Total Aromatic Bonds10
Networks2
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This ligand is also present in the following 2 networks:
Show PDB Class SubFamily Type SubType Species Orthosteric Ligand Other Ligand(s) Protein Partners Resolution Date DOI
8YH3 A Nucleotide Adenosine A3A Homo Sapiens N-methyladenosine - Gi1/Beta1/Gamma2 3.4 2024-11-06 doi.org/10.1038/s41467-024-53473-1

A 2D representation of the interactions of 6MD in 8YH3
colored according to ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

(Click to enlarge 🔍)
Node1 Node2 LinkStrength Comm IsNode1Hub? IsNode2Hub? Node1Cons Node2Cons Node1Shell Node2Shell
R:R:E19 R:R:Y15 7.86 3 Yes Yes 5 4 2 2
R:R:I268 R:R:Y15 12.09 3 Yes Yes 5 4 1 2
R:R:A69 R:R:E19 3.02 0 No Yes 6 5 2 2
R:R:E19 R:R:I268 4.1 3 Yes Yes 5 5 2 1
R:R:E19 R:R:H272 16 3 Yes Yes 5 7 2 1
R:R:M90 R:R:V65 9.13 0 Yes No 6 7 1 2
R:R:H272 R:R:V65 4.15 3 Yes No 7 7 1 2
R:R:L68 R:R:M90 4.24 0 Yes Yes 5 6 2 1
R:R:A69 R:R:M90 3.22 0 No Yes 6 6 2 1
R:R:F168 R:R:T87 5.19 3 Yes Yes 5 4 1 2
R:R:M172 R:R:T87 4.52 3 Yes Yes 4 4 2 2
L:L:?1 R:R:M90 6.45 3 Yes Yes 0 6 0 1
R:R:F168 R:R:M172 7.46 3 Yes Yes 5 4 1 2
R:R:F168 R:R:M177 8.71 3 Yes Yes 5 5 1 1
L:L:?1 R:R:F168 26.18 3 Yes Yes 0 5 0 1
R:R:M172 R:R:Y176 7.18 3 Yes Yes 4 6 2 2
R:R:M172 R:R:M177 2.89 3 Yes Yes 4 5 2 1
R:R:M174 R:R:N250 5.61 0 No No 3 5 2 1
R:R:M177 R:R:Y176 5.99 3 Yes Yes 5 6 1 2
R:R:M177 R:R:S181 3.07 3 Yes No 5 5 1 2
L:L:?1 R:R:M177 5.52 3 Yes Yes 0 5 0 1
R:R:L246 R:R:N250 2.75 3 Yes No 6 5 1 1
R:R:G267 R:R:L246 3.42 0 No Yes 6 6 2 1
R:R:I268 R:R:L246 2.85 3 Yes Yes 5 6 1 1
R:R:L246 R:R:S271 3 3 Yes No 6 7 1 2
L:L:?1 R:R:L246 13.52 3 Yes Yes 0 6 0 1
L:L:?1 R:R:N250 14.31 3 Yes No 0 5 0 1
R:R:L264 R:R:Q261 9.32 0 No No 4 2 1 2
L:L:?1 R:R:L264 9.92 3 Yes No 0 4 0 1
R:R:H272 R:R:I268 6.63 3 Yes Yes 7 5 1 1
L:L:?1 R:R:I268 11.16 3 Yes Yes 0 5 0 1
L:L:?1 R:R:H272 6.7 3 Yes Yes 0 7 0 1
StatisticsValue
Average Number Of Links8.00
Average Number Of Links With An Hub6.00
Average Interaction Strength11.72
Average Nodes In Shell22.00
Average Hubs In Shell13.00
Average Links In Shell32.00
Average Links Mediated by Hubs In Shell30.00
Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)
Location of the nodes interacting with this ligand (click to enlarge 🔍)
StatisticsValue
Average Number Of Links8.00
Average Number Of Links With An Hub5.00
Average Interaction Strength11.72
Average Nodes In Shell21.00
Average Hubs In Shell11.50
Average Links In Shell29.00
Average Links Mediated by Hubs In Shell26.50

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Physico-chemical properties of the nodes interacting with this ligand

(Click to enlarge 🔍)

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Location of the nodes interacting with this ligand

(Click to enlarge 🔍)