Code8IA
Name~{N},~{N}-dimethylcyclohexanamine
Synonyms
Identifier~{N},~{N}-dimethylcyclohexanamine
FormulaC8 H17 N
Molecular Weight127.227
SMILESCN(C)C1CCCCC1
PubChem7415
Formal Charge0
Total Atoms26
Total Chiral Atoms0
Total Bonds26
Total Aromatic Bonds0
Networks1
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This ligand is also present in the following network:
Show PDB Class SubFamily Type SubType Species Orthosteric Ligand Other Ligand(s) Protein Partners Resolution Date DOI
8ITF A Orphan A orphans TAAR9 Mus Musculus DMCHA - chim(NtGi1-Gs)/Beta1/Gamma2 3.46 2023-05-31 10.1038/s41586-023-06106-4

A 2D representation of the interactions of 8IA in 8ITF
colored according to ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

(Click to enlarge 🔍)
Node1 Node2 LinkStrength Comm IsNode1Hub? IsNode2Hub? Node1Cons Node2Cons Node1Shell Node2Shell
R:R:D112 R:R:V85 7.3 1 No Yes 6 7 1 2
R:R:D112 R:R:Y301 13.79 1 No Yes 6 8 1 1
L:L:?1 R:R:D112 12.68 1 Yes No 0 6 0 1
R:R:T113 R:R:Y163 7.49 1 No Yes 4 5 1 2
R:R:F168 R:R:T113 11.67 1 Yes No 5 4 2 1
L:L:?1 R:R:T113 8.6 1 Yes No 0 4 0 1
R:R:F117 R:R:L205 4.87 1 No No 5 4 1 2
R:R:F117 R:R:W271 4.01 1 No Yes 5 8 1 1
L:L:?1 R:R:F117 5.69 1 Yes No 0 5 0 1
R:R:F168 R:R:Y163 3.09 1 Yes Yes 5 5 2 2
R:R:L205 R:R:Y163 2.34 0 No Yes 4 5 2 2
R:R:F206 R:R:W271 8.02 0 Yes Yes 8 8 2 1
R:R:F267 R:R:W271 4.01 0 Yes Yes 9 8 2 1
R:R:S270 R:R:W271 4.94 0 No Yes 8 8 2 1
R:R:V300 R:R:W271 3.68 1 No Yes 7 8 1 1
L:L:?1 R:R:W271 2.66 1 Yes Yes 0 8 0 1
R:R:Y274 R:R:Y293 4.96 1 Yes No 6 4 1 2
R:R:V297 R:R:Y274 2.52 1 Yes Yes 6 6 1 1
R:R:V300 R:R:Y274 2.52 1 No Yes 7 6 1 1
L:L:?1 R:R:Y274 13.69 1 Yes Yes 0 6 0 1
R:R:V297 R:R:Y293 5.05 1 Yes No 6 4 1 2
R:R:V297 R:R:Y301 6.31 1 Yes Yes 6 8 1 1
L:L:?1 R:R:V297 5.22 1 Yes Yes 0 6 0 1
R:R:W298 R:R:Y301 6.75 1 Yes Yes 5 8 2 1
L:L:?1 R:R:V300 3.48 1 Yes No 0 7 0 1
L:L:?1 R:R:Y301 12.32 1 Yes Yes 0 8 0 1
StatisticsValue
Average Number Of Links8.00
Average Number Of Links With An Hub4.00
Average Interaction Strength8.04
Average Nodes In Shell18.00
Average Hubs In Shell11.00
Average Links In Shell26.00
Average Links Mediated by Hubs In Shell25.00
Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)
Location of the nodes interacting with this ligand (click to enlarge 🔍)
StatisticsValue
Average Number Of Links8.00
Average Number Of Links With An Hub4.00
Average Interaction Strength8.04
Average Nodes In Shell18.00
Average Hubs In Shell11.00
Average Links In Shell26.00
Average Links Mediated by Hubs In Shell25.00

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Physico-chemical properties of the nodes interacting with this ligand

(Click to enlarge 🔍)

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Location of the nodes interacting with this ligand

(Click to enlarge 🔍)