Code9GL
Name5-chloro-3-ethyl-N-{2-[4-(piperidin-1-yl)phenyl]ethyl}-1H-indole-2-carboxamide
Synonyms
Identifier5-chloranyl-3-ethyl-~{N}-[2-(4-piperidin-1-ylphenyl)ethyl]-1~{H}-indole-2-carboxamide
FormulaC24 H28 Cl N3 O
Molecular Weight409.952
SMILESCCc1c2cc(ccc2[nH]c1C(=O)NCCc3ccc(cc3)N4CCCCC4)Cl
PubChem44828492
Formal Charge0
Total Atoms57
Total Chiral Atoms0
Total Bonds60
Total Aromatic Bonds16
Networks1
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This ligand is also present in the following network:
Show PDB Class SubFamily Type SubType Species Orthosteric Ligand Other Ligand(s) Protein Partners Resolution Date DOI
6KQI A Lipid Cannabinoid CB1 Homo sapiens PubMed 104895 ORG27569 - 3.25 2019-10-23 10.1038/s41589-019-0387-2

A 2D representation of the interactions of 9GL in 6KQI
colored according to ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

(Click to enlarge 🔍)
Node1 Node2 LinkStrength Comm IsNode1Hub? IsNode2Hub? Node1Cons Node2Cons Node1Shell Node2Shell
R:R:H154 R:R:R230 6.77 0 No Yes 3 1 1 2
R:R:F237 R:R:H154 16.97 3 Yes No 8 3 2 1
R:R:H154 W:W:?2 16.19 0 No Yes 3 0 1 0
R:R:G157 W:W:?2 3.31 0 No Yes 6 0 1 0
R:R:F237 R:R:S158 9.25 3 Yes No 8 9 2 2
R:R:S158 R:R:W241 6.18 3 No Yes 9 9 2 1
R:R:A202 R:R:W241 7.78 0 No Yes 7 9 2 1
R:R:F237 R:R:M240 3.73 3 Yes Yes 8 6 2 2
R:R:C238 W:W:?2 9.22 0 No Yes 4 0 1 0
R:R:M240 R:R:W241 5.82 3 Yes Yes 6 9 2 1
R:R:W241 W:W:?2 22.06 0 Yes Yes 9 0 1 0
R:R:T242 W:W:?2 8.57 0 No Yes 4 0 1 0
R:R:I245 W:W:?2 8.3 0 No Yes 4 0 1 0
R:R:L239 R:R:T242 2.95 0 No No 3 4 2 1
R:R:A162 R:R:W241 2.59 0 No Yes 8 9 2 1
StatisticsValue
Average Number Of Links6.00
Average Number Of Links With An Hub1.00
Average Interaction Strength11.28
Average Nodes In Shell14.00
Average Hubs In Shell5.00
Average Links In Shell15.00
Average Links Mediated by Hubs In Shell14.00
Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)
Location of the nodes interacting with this ligand (click to enlarge 🔍)
StatisticsValue
Average Number Of Links6.00
Average Number Of Links With An Hub1.00
Average Interaction Strength11.28
Average Nodes In Shell14.00
Average Hubs In Shell5.00
Average Links In Shell15.00
Average Links Mediated by Hubs In Shell14.00

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Physico-chemical properties of the nodes interacting with this ligand

(Click to enlarge 🔍)

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Location of the nodes interacting with this ligand

(Click to enlarge 🔍)