CodeABU
Namegamma-Aminobutyric acid
Synonyms4Abu
Identifier
FormulaC4 H9 N O2
Molecular Weight103.12
SMILES
PubChem119
Formal Charge0
Total Atoms16
Total Chiral Atoms0
Total Bonds15
Total Aromatic Bonds0
Networks2
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This ligand is also present in the following 2 networks:
Show PDB Class SubFamily Type SubType Species Orthosteric Ligand Other Ligand(s) Protein Partners Resolution Date DOI
9JR0 C Aminoacid GABAB GABAB2; GABAB1 Drosophila melanogaster GABA - Gi1/Beta1/Gamma2 3.06 2025-10-22 To be published

A 2D representation of the interactions of ABU in 9JR0
colored according to ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

(Click to enlarge 🔍)
Node1 Node2 LinkStrength Comm IsNode1Hub? IsNode2Hub? Node1Cons Node2Cons Node1Shell Node2Shell
M:M:?1 S:S:W51 15.99 1 Yes Yes 0 5 0 1
M:M:?1 S:S:S116 7.03 1 Yes No 0 8 0 1
M:M:?1 S:S:S139 8.43 1 Yes No 0 7 0 1
M:M:?1 S:S:H156 9.63 1 Yes Yes 0 6 0 1
M:M:?1 S:S:Y236 4.39 1 Yes Yes 0 7 0 1
M:M:?1 S:S:W264 17.06 1 Yes Yes 0 4 0 1
M:M:?1 S:S:E343 9.92 1 Yes Yes 0 5 0 1
S:S:P44 S:S:W51 2.7 1 Yes Yes 8 5 2 1
S:S:G50 S:S:Y236 10.14 0 No Yes 2 7 2 1
S:S:G53 S:S:W51 9.85 0 No Yes 4 5 2 1
S:S:G137 S:S:W51 2.81 0 No Yes 7 5 2 1
S:S:W264 S:S:W51 6.56 1 Yes Yes 4 5 1 1
S:S:E339 S:S:W51 8.72 1 Yes Yes 4 5 2 1
S:S:G340 S:S:W51 4.22 0 No Yes 3 5 2 1
S:S:E343 S:S:W51 11.99 1 Yes Yes 5 5 1 1
S:S:S116 S:S:S140 4.89 1 No Yes 8 8 1 2
S:S:S116 S:S:V187 6.46 1 No No 8 5 1 2
S:S:G137 S:S:H156 4.77 0 No Yes 7 6 2 1
S:S:H156 S:S:S139 5.58 1 Yes No 6 7 1 1
S:S:A159 S:S:S139 3.42 1 No No 7 7 2 1
S:S:S140 S:S:V187 6.46 1 Yes No 8 5 2 2
S:S:H156 S:S:P157 7.63 1 Yes No 6 7 1 2
S:S:H156 S:S:M300 7.88 1 Yes Yes 6 5 1 2
S:S:E343 S:S:H156 4.92 1 Yes Yes 5 6 1 1
S:S:H156 S:S:L346 5.14 1 Yes Yes 6 6 1 2
S:S:M300 S:S:P157 5.03 1 Yes No 5 7 2 2
S:S:E185 S:S:Q183 7.65 1 Yes Yes 5 8 2 2
S:S:F188 S:S:Q183 4.68 1 Yes Yes 6 8 2 2
S:S:Q183 S:S:Y236 3.38 1 Yes Yes 8 7 2 1
S:S:E185 S:S:F188 4.66 1 Yes Yes 5 6 2 2
S:S:E185 S:S:Y236 3.37 1 Yes Yes 5 7 2 1
S:S:F188 S:S:V187 9.18 1 Yes No 6 5 2 2
S:S:F188 S:S:Y236 11.35 1 Yes Yes 6 7 2 1
S:S:W264 S:S:Y236 3.86 1 Yes Yes 4 7 1 1
S:S:I262 S:S:W264 10.57 1 No Yes 4 4 2 1
S:S:I262 S:S:Y265 8.46 1 No Yes 4 6 2 2
S:S:W264 S:S:Y265 5.79 1 Yes Yes 4 6 1 2
S:S:E343 S:S:W264 5.45 1 Yes Yes 5 4 1 1
S:S:E343 S:S:M300 6.77 1 Yes Yes 5 5 1 2
S:S:L346 S:S:M300 7.07 1 Yes Yes 6 5 2 2
S:S:E343 S:S:Q342 5.1 1 Yes No 5 4 1 2
S:S:E343 S:S:L346 2.65 1 Yes Yes 5 6 1 2
StatisticsValue
Average Number Of Links7.00
Average Number Of Links With An Hub5.00
Average Interaction Strength10.35
Average Nodes In Shell26.00
Average Hubs In Shell15.00
Average Links In Shell42.00
Average Links Mediated by Hubs In Shell40.00
Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)
Location of the nodes interacting with this ligand (click to enlarge 🔍)
StatisticsValue
Average Number Of Links7.00
Average Number Of Links With An Hub5.00
Average Interaction Strength10.35
Average Nodes In Shell25.50
Average Hubs In Shell14.50
Average Links In Shell40.50
Average Links Mediated by Hubs In Shell38.50

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Physico-chemical properties of the nodes interacting with this ligand

(Click to enlarge 🔍)

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Location of the nodes interacting with this ligand

(Click to enlarge 🔍)