Show | PDB | Class | SubFamily | Type | SubType | Species | Orthosteric Ligand | Other Ligand(s) | Protein Partners | Resolution | Date | DOI |
| 7T8X | A | Amine | Acetylcholine (muscarinic) | M2 | Homo Sapiens | Acetylcholine | - | chim(NtGi1-Go)/Beta1/Gamma2 | 3.21 | 2023-01-25 | 10.1038/s41467-022-35726-z |
![](/psngpcr/ligands/ACH/ACH_7T8X_L_L_1.png)
A 2D representation of the interactions of ACH in 7T8X colored according to ConSurf Conservation Grade (See documentation):
(Click to enlarge 🔍) | Node1 | Node2 | LinkStrength | Comm | IsNode1Hub? | IsNode2Hub? | Node1Cons | Node2Cons | Node1Shell | Node2Shell | R:R:I72 | R:R:S76 | 3.1 | 2 | Yes | No | 8 | 8 | 2 | 2 | R:R:I72 | R:R:S107 | 4.64 | 2 | Yes | No | 8 | 8 | 2 | 1 | R:R:I72 | R:R:Y430 | 2.42 | 2 | Yes | Yes | 8 | 9 | 2 | 1 | R:R:D103 | R:R:S76 | 10.31 | 2 | No | No | 9 | 8 | 1 | 2 | R:R:S76 | R:R:Y430 | 6.36 | 2 | No | Yes | 8 | 9 | 2 | 1 | R:R:M77 | R:R:W427 | 11.63 | 2 | Yes | Yes | 9 | 9 | 2 | 2 | R:R:M77 | R:R:Y430 | 2.39 | 2 | Yes | Yes | 9 | 9 | 2 | 1 | R:R:Y426 | R:R:Y80 | 9.93 | 2 | Yes | Yes | 7 | 8 | 1 | 2 | R:R:W427 | R:R:Y80 | 5.79 | 2 | Yes | Yes | 9 | 8 | 2 | 2 | R:R:Y430 | R:R:Y80 | 4.96 | 2 | Yes | Yes | 9 | 8 | 1 | 2 | R:R:D103 | R:R:Y430 | 8.05 | 2 | No | Yes | 9 | 9 | 1 | 1 | L:L:?1 | R:R:D103 | 5.93 | 2 | Yes | No | 0 | 9 | 0 | 1 | R:R:W155 | R:R:Y104 | 13.5 | 2 | Yes | Yes | 8 | 8 | 1 | 1 | R:R:I159 | R:R:Y104 | 2.42 | 2 | Yes | Yes | 8 | 8 | 2 | 1 | R:R:I178 | R:R:Y104 | 12.09 | 2 | Yes | Yes | 7 | 8 | 2 | 1 | R:R:F181 | R:R:Y104 | 2.06 | 2 | Yes | Yes | 5 | 8 | 2 | 1 | R:R:Y104 | R:R:Y403 | 4.96 | 2 | Yes | Yes | 8 | 8 | 1 | 1 | R:R:Y104 | R:R:Y426 | 5.96 | 2 | Yes | Yes | 8 | 7 | 1 | 1 | L:L:?1 | R:R:Y104 | 13.32 | 2 | Yes | Yes | 0 | 8 | 0 | 1 | R:R:S107 | R:R:W400 | 2.47 | 2 | No | Yes | 8 | 9 | 1 | 1 | L:L:?1 | R:R:S107 | 7.87 | 2 | Yes | No | 0 | 8 | 0 | 1 | R:R:L154 | R:R:N108 | 4.12 | 2 | No | Yes | 8 | 9 | 2 | 2 | R:R:N108 | R:R:W155 | 10.17 | 2 | Yes | Yes | 9 | 8 | 2 | 1 | R:R:V111 | R:R:W400 | 6.13 | 0 | No | Yes | 9 | 9 | 2 | 1 | R:R:L154 | R:R:W155 | 9.11 | 2 | No | Yes | 8 | 8 | 2 | 1 | R:R:I159 | R:R:W155 | 3.52 | 2 | Yes | Yes | 8 | 8 | 2 | 1 | R:R:T190 | R:R:W155 | 8.49 | 0 | No | Yes | 9 | 8 | 2 | 1 | L:L:?1 | R:R:W155 | 5.97 | 2 | Yes | Yes | 0 | 8 | 0 | 1 | R:R:I159 | R:R:I178 | 2.94 | 2 | Yes | Yes | 8 | 7 | 2 | 2 | R:R:F181 | R:R:I178 | 3.77 | 2 | Yes | Yes | 5 | 7 | 2 | 2 | R:R:F181 | R:R:Y403 | 2.06 | 2 | Yes | Yes | 5 | 8 | 2 | 1 | R:R:F195 | R:R:F396 | 5.36 | 2 | Yes | Yes | 9 | 9 | 2 | 2 | R:R:F195 | R:R:W400 | 4.01 | 2 | Yes | Yes | 9 | 9 | 2 | 1 | R:R:F195 | R:R:N404 | 14.5 | 2 | Yes | No | 9 | 7 | 2 | 2 | R:R:F396 | R:R:W400 | 10.02 | 2 | Yes | Yes | 9 | 9 | 2 | 1 | R:R:T399 | R:R:W400 | 6.06 | 2 | No | Yes | 9 | 9 | 2 | 1 | R:R:N432 | R:R:T399 | 11.7 | 2 | No | No | 9 | 9 | 2 | 2 | R:R:N432 | R:R:W400 | 13.56 | 2 | No | Yes | 9 | 9 | 2 | 1 | L:L:?1 | R:R:W400 | 8.96 | 2 | Yes | Yes | 0 | 9 | 0 | 1 | R:R:N404 | R:R:Y403 | 4.65 | 0 | No | Yes | 7 | 8 | 2 | 1 | R:R:V407 | R:R:Y403 | 5.05 | 0 | No | Yes | 8 | 8 | 2 | 1 | R:R:Y403 | R:R:Y426 | 5.96 | 2 | Yes | Yes | 8 | 7 | 1 | 1 | R:R:C429 | R:R:Y403 | 4.03 | 2 | No | Yes | 8 | 8 | 1 | 1 | L:L:?1 | R:R:Y403 | 10.24 | 2 | Yes | Yes | 0 | 8 | 0 | 1 | R:R:W422 | R:R:Y426 | 7.72 | 2 | No | Yes | 6 | 7 | 2 | 1 | R:R:Y426 | R:R:Y430 | 4.96 | 2 | Yes | Yes | 7 | 9 | 1 | 1 | L:L:?1 | R:R:Y426 | 7.17 | 2 | Yes | Yes | 0 | 7 | 0 | 1 | R:R:W427 | R:R:Y430 | 8.68 | 2 | Yes | Yes | 9 | 9 | 2 | 1 | L:L:?1 | R:R:C429 | 5.55 | 2 | Yes | No | 0 | 8 | 0 | 1 | L:L:?1 | R:R:Y430 | 5.12 | 2 | Yes | Yes | 0 | 9 | 0 | 1 | R:R:A194 | R:R:W155 | 1.3 | 0 | No | Yes | 8 | 8 | 2 | 1 | |
Statistics | Value |
---|
Average Number Of Links | 9.00 | Average Number Of Links With An Hub | 6.00 | Average Interaction Strength | 7.79 | Average Nodes In Shell | 30.00 | Average Hubs In Shell | 17.00 | Average Links In Shell | 51.00 | Average Links Mediated by Hubs In Shell | 49.00 |
| ![](/psngpcr/ligands/ACH/ACH_7T8X_L_L_1_res_stats.svg) Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍) | ![](/psngpcr/ligands/ACH/ACH_7T8X_L_L_1_pos_stats.svg) Location of the nodes interacting with this ligand (click to enlarge 🔍) |
|
Show | PDB | Class | SubFamily | Type | SubType | Species | Orthosteric Ligand | Other Ligand(s) | Protein Partners | Resolution | Date | DOI |
| 7T90 | A | Amine | Acetylcholine (muscarinic) | M2 | Homo Sapiens | Acetylcholine | - | chim(NtGi1-Go)/Beta1/Gamma2 | 3.32 | 2023-01-25 | 10.1038/s41467-022-35726-z |
![](/psngpcr/ligands/ACH/ACH_7T90_L_L_1.png)
A 2D representation of the interactions of ACH in 7T90 colored according to ConSurf Conservation Grade (See documentation):
(Click to enlarge 🔍) | Node1 | Node2 | LinkStrength | Comm | IsNode1Hub? | IsNode2Hub? | Node1Cons | Node2Cons | Node1Shell | Node2Shell | R:R:D103 | R:R:I72 | 2.8 | 2 | Yes | Yes | 9 | 8 | 1 | 2 | R:R:I72 | R:R:S107 | 3.1 | 0 | Yes | No | 8 | 8 | 2 | 1 | R:R:D103 | R:R:S76 | 8.83 | 2 | Yes | No | 9 | 8 | 1 | 2 | R:R:S76 | R:R:Y430 | 5.09 | 2 | No | Yes | 8 | 9 | 2 | 1 | R:R:M77 | R:R:Y430 | 5.99 | 0 | No | Yes | 9 | 9 | 2 | 1 | R:R:Y426 | R:R:Y80 | 6.95 | 2 | Yes | Yes | 7 | 8 | 1 | 2 | R:R:W427 | R:R:Y80 | 4.82 | 2 | Yes | Yes | 9 | 8 | 2 | 2 | R:R:Y430 | R:R:Y80 | 2.98 | 2 | Yes | Yes | 9 | 8 | 1 | 2 | R:R:D103 | R:R:Y430 | 10.34 | 2 | Yes | Yes | 9 | 9 | 1 | 1 | L:L:?1 | R:R:D103 | 5.93 | 2 | Yes | Yes | 0 | 9 | 0 | 1 | R:R:W155 | R:R:Y104 | 12.54 | 2 | Yes | Yes | 8 | 8 | 1 | 1 | R:R:I159 | R:R:Y104 | 2.42 | 2 | Yes | Yes | 8 | 8 | 2 | 1 | R:R:I178 | R:R:Y104 | 8.46 | 2 | Yes | Yes | 7 | 8 | 2 | 1 | R:R:F181 | R:R:Y104 | 7.22 | 2 | No | Yes | 5 | 8 | 2 | 1 | R:R:Y104 | R:R:Y403 | 3.97 | 2 | Yes | Yes | 8 | 8 | 1 | 1 | R:R:Y104 | R:R:Y426 | 2.98 | 2 | Yes | Yes | 8 | 7 | 1 | 1 | L:L:?1 | R:R:Y104 | 7.17 | 2 | Yes | Yes | 0 | 8 | 0 | 1 | L:L:?1 | R:R:S107 | 7.87 | 2 | Yes | No | 0 | 8 | 0 | 1 | R:R:N108 | R:R:W155 | 7.91 | 0 | Yes | Yes | 9 | 8 | 2 | 1 | R:R:V111 | R:R:W400 | 3.68 | 0 | No | Yes | 9 | 9 | 2 | 1 | R:R:I159 | R:R:W155 | 2.35 | 2 | Yes | Yes | 8 | 8 | 2 | 1 | R:R:T190 | R:R:W155 | 10.92 | 0 | No | Yes | 9 | 8 | 2 | 1 | L:L:?1 | R:R:W155 | 3.98 | 2 | Yes | Yes | 0 | 8 | 0 | 1 | R:R:I159 | R:R:I178 | 11.77 | 2 | Yes | Yes | 8 | 7 | 2 | 2 | R:R:F181 | R:R:Y403 | 5.16 | 2 | No | Yes | 5 | 8 | 2 | 1 | R:R:F195 | R:R:F396 | 3.22 | 2 | Yes | Yes | 9 | 9 | 2 | 2 | R:R:F195 | R:R:W400 | 5.01 | 2 | Yes | Yes | 9 | 9 | 2 | 1 | R:R:F396 | R:R:W400 | 6.01 | 2 | Yes | Yes | 9 | 9 | 2 | 1 | R:R:F396 | R:R:N432 | 4.83 | 2 | Yes | No | 9 | 9 | 2 | 2 | R:R:T399 | R:R:W400 | 6.06 | 0 | No | Yes | 9 | 9 | 2 | 1 | R:R:N432 | R:R:W400 | 5.65 | 2 | No | Yes | 9 | 9 | 2 | 1 | L:L:?1 | R:R:W400 | 9.95 | 2 | Yes | Yes | 0 | 9 | 0 | 1 | R:R:V407 | R:R:Y403 | 8.83 | 0 | No | Yes | 8 | 8 | 2 | 1 | R:R:Y403 | R:R:Y426 | 3.97 | 2 | Yes | Yes | 8 | 7 | 1 | 1 | R:R:C429 | R:R:Y403 | 4.03 | 2 | No | Yes | 8 | 8 | 1 | 1 | L:L:?1 | R:R:Y403 | 4.1 | 2 | Yes | Yes | 0 | 8 | 0 | 1 | R:R:W422 | R:R:Y426 | 8.68 | 0 | No | Yes | 6 | 7 | 2 | 1 | R:R:Y426 | R:R:Y430 | 2.98 | 2 | Yes | Yes | 7 | 9 | 1 | 1 | L:L:?1 | R:R:Y426 | 8.2 | 2 | Yes | Yes | 0 | 7 | 0 | 1 | R:R:W427 | R:R:Y430 | 3.86 | 2 | Yes | Yes | 9 | 9 | 2 | 1 | L:L:?1 | R:R:C429 | 6.93 | 2 | Yes | No | 0 | 8 | 0 | 1 | L:L:?1 | R:R:Y430 | 15.37 | 2 | Yes | Yes | 0 | 9 | 0 | 1 | |
Statistics | Value |
---|
Average Number Of Links | 9.00 | Average Number Of Links With An Hub | 7.00 | Average Interaction Strength | 7.72 | Average Nodes In Shell | 27.00 | Average Hubs In Shell | 16.00 | Average Links In Shell | 42.00 | Average Links Mediated by Hubs In Shell | 42.00 |
| ![](/psngpcr/ligands/ACH/ACH_7T90_L_L_1_res_stats.svg) Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍) | ![](/psngpcr/ligands/ACH/ACH_7T90_L_L_1_pos_stats.svg) Location of the nodes interacting with this ligand (click to enlarge 🔍) |
|
Show | PDB | Class | SubFamily | Type | SubType | Species | Orthosteric Ligand | Other Ligand(s) | Protein Partners | Resolution | Date | DOI |
| 7T94 | A | Amine | Acetylcholine (muscarinic) | M2 | Homo Sapiens | Acetylcholine | PubChem 57664406 | chim(NtGi1-Go)/Beta1/Gamma2 | 3.16 | 2023-01-25 | 10.1038/s41467-022-35726-z |
![](/psngpcr/ligands/ACH/ACH_7T94_L_L_1.png)
A 2D representation of the interactions of ACH in 7T94 colored according to ConSurf Conservation Grade (See documentation):
(Click to enlarge 🔍) | Node1 | Node2 | LinkStrength | Comm | IsNode1Hub? | IsNode2Hub? | Node1Cons | Node2Cons | Node1Shell | Node2Shell | R:R:I72 | R:R:S76 | 4.64 | 1 | No | Yes | 8 | 8 | 2 | 2 | R:R:I72 | R:R:Y430 | 8.46 | 1 | No | Yes | 8 | 9 | 2 | 1 | R:R:D103 | R:R:S76 | 4.42 | 1 | Yes | Yes | 9 | 8 | 1 | 2 | R:R:S76 | R:R:Y430 | 10.17 | 1 | Yes | Yes | 8 | 9 | 2 | 1 | R:R:M77 | R:R:W427 | 3.49 | 1 | Yes | Yes | 9 | 9 | 2 | 2 | R:R:M77 | R:R:Y430 | 8.38 | 1 | Yes | Yes | 9 | 9 | 2 | 1 | R:R:Y426 | R:R:Y80 | 13.9 | 1 | Yes | Yes | 7 | 8 | 1 | 2 | R:R:W427 | R:R:Y80 | 4.82 | 1 | Yes | Yes | 9 | 8 | 2 | 2 | R:R:Y80 | W:W:?1 | 7.76 | 1 | Yes | Yes | 8 | 0 | 2 | 2 | R:R:D103 | R:R:S107 | 2.94 | 1 | Yes | No | 9 | 8 | 1 | 1 | R:R:D103 | R:R:Y426 | 2.3 | 1 | Yes | Yes | 9 | 7 | 1 | 1 | R:R:D103 | R:R:Y430 | 3.45 | 1 | Yes | Yes | 9 | 9 | 1 | 1 | L:L:?1 | R:R:D103 | 11.86 | 1 | Yes | Yes | 0 | 9 | 0 | 1 | R:R:W155 | R:R:Y104 | 13.5 | 1 | Yes | Yes | 8 | 8 | 1 | 1 | R:R:I159 | R:R:Y104 | 4.84 | 1 | Yes | Yes | 8 | 8 | 2 | 1 | R:R:Y104 | R:R:Y403 | 5.96 | 1 | Yes | Yes | 8 | 8 | 1 | 1 | L:L:?1 | R:R:Y104 | 16.39 | 1 | Yes | Yes | 0 | 8 | 0 | 1 | L:L:?1 | R:R:S107 | 13.12 | 1 | Yes | No | 0 | 8 | 0 | 1 | R:R:N108 | R:R:W155 | 7.91 | 0 | No | Yes | 9 | 8 | 2 | 1 | R:R:F396 | R:R:V111 | 5.24 | 1 | Yes | Yes | 9 | 9 | 2 | 2 | R:R:V111 | R:R:W400 | 4.9 | 1 | Yes | Yes | 9 | 9 | 2 | 1 | R:R:L154 | R:R:W155 | 2.28 | 0 | No | Yes | 8 | 8 | 2 | 1 | R:R:T190 | R:R:W155 | 8.49 | 0 | No | Yes | 9 | 8 | 2 | 1 | R:R:A194 | R:R:W155 | 2.59 | 1 | No | Yes | 8 | 8 | 1 | 1 | L:L:?1 | R:R:W155 | 1.99 | 1 | Yes | Yes | 0 | 8 | 0 | 1 | L:L:?1 | R:R:A194 | 2.75 | 1 | Yes | No | 0 | 8 | 0 | 1 | R:R:F195 | R:R:F396 | 5.36 | 1 | Yes | Yes | 9 | 9 | 2 | 2 | R:R:F195 | R:R:W400 | 5.01 | 1 | Yes | Yes | 9 | 9 | 2 | 1 | R:R:F195 | R:R:N404 | 16.92 | 1 | Yes | No | 9 | 7 | 2 | 2 | R:R:F396 | R:R:W400 | 3.01 | 1 | Yes | Yes | 9 | 9 | 2 | 1 | R:R:F396 | R:R:N432 | 3.62 | 1 | Yes | Yes | 9 | 9 | 2 | 2 | R:R:T399 | R:R:W400 | 6.06 | 1 | No | Yes | 9 | 9 | 2 | 1 | R:R:N432 | R:R:T399 | 13.16 | 1 | Yes | No | 9 | 9 | 2 | 2 | R:R:N404 | R:R:W400 | 2.26 | 1 | No | Yes | 7 | 9 | 2 | 1 | R:R:C429 | R:R:W400 | 3.92 | 1 | No | Yes | 8 | 9 | 1 | 1 | R:R:N432 | R:R:W400 | 9.04 | 1 | Yes | Yes | 9 | 9 | 2 | 1 | L:L:?1 | R:R:W400 | 9.95 | 1 | Yes | Yes | 0 | 9 | 0 | 1 | R:R:N404 | R:R:Y403 | 6.98 | 1 | No | Yes | 7 | 8 | 2 | 1 | R:R:V407 | R:R:Y403 | 6.31 | 0 | No | Yes | 8 | 8 | 2 | 1 | R:R:C429 | R:R:Y403 | 2.69 | 1 | No | Yes | 8 | 8 | 1 | 1 | L:L:?1 | R:R:Y403 | 11.27 | 1 | Yes | Yes | 0 | 8 | 0 | 1 | R:R:Y426 | R:R:Y430 | 6.95 | 1 | Yes | Yes | 7 | 9 | 1 | 1 | L:L:?1 | R:R:Y426 | 8.2 | 1 | Yes | Yes | 0 | 7 | 0 | 1 | R:R:Y426 | W:W:?1 | 6.03 | 1 | Yes | Yes | 7 | 0 | 1 | 2 | R:R:W427 | R:R:Y430 | 5.79 | 1 | Yes | Yes | 9 | 9 | 2 | 1 | L:L:?1 | R:R:C429 | 4.16 | 1 | Yes | No | 0 | 8 | 0 | 1 | L:L:?1 | R:R:Y430 | 3.07 | 1 | Yes | Yes | 0 | 9 | 0 | 1 | |
Statistics | Value |
---|
Average Number Of Links | 10.00 | Average Number Of Links With An Hub | 7.00 | Average Interaction Strength | 8.28 | Average Nodes In Shell | 28.00 | Average Hubs In Shell | 18.00 | Average Links In Shell | 47.00 | Average Links Mediated by Hubs In Shell | 47.00 |
| ![](/psngpcr/ligands/ACH/ACH_7T94_L_L_1_res_stats.svg) Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍) | ![](/psngpcr/ligands/ACH/ACH_7T94_L_L_1_pos_stats.svg) Location of the nodes interacting with this ligand (click to enlarge 🔍) |
|
Show | PDB | Class | SubFamily | Type | SubType | Species | Orthosteric Ligand | Other Ligand(s) | Protein Partners | Resolution | Date | DOI |
| 7TRS | A | Amine | Acetylcholine (muscarinic) | M4 | Homo sapiens | Acetylcholine | - | Gi1/Beta1/Gamma2 | 2.8 | 2023-05-17 | 10.2139/ssrn.4034884 |
![](/psngpcr/ligands/ACH/ACH_7TRS_L_L_1.png)
A 2D representation of the interactions of ACH in 7TRS colored according to ConSurf Conservation Grade (See documentation):
(Click to enlarge 🔍) | Node1 | Node2 | LinkStrength | Comm | IsNode1Hub? | IsNode2Hub? | Node1Cons | Node2Cons | Node1Shell | Node2Shell | R:R:I81 | R:R:S85 | 6.19 | 3 | Yes | No | 9 | 9 | 2 | 2 | R:R:I81 | R:R:S116 | 4.64 | 3 | Yes | No | 9 | 8 | 2 | 1 | R:R:I81 | R:R:Y443 | 4.84 | 3 | Yes | Yes | 9 | 9 | 2 | 1 | R:R:D112 | R:R:S85 | 10.31 | 3 | Yes | No | 9 | 9 | 1 | 2 | R:R:S85 | R:R:Y443 | 6.36 | 3 | No | Yes | 9 | 9 | 2 | 1 | R:R:M86 | R:R:W440 | 6.98 | 3 | Yes | Yes | 9 | 9 | 2 | 2 | R:R:M86 | R:R:Y443 | 8.38 | 3 | Yes | Yes | 9 | 9 | 2 | 1 | R:R:Y439 | R:R:Y89 | 25.81 | 3 | Yes | Yes | 7 | 8 | 1 | 2 | R:R:D112 | R:R:S116 | 2.94 | 3 | Yes | No | 9 | 8 | 1 | 1 | R:R:D112 | R:R:Y439 | 3.45 | 3 | Yes | Yes | 9 | 7 | 1 | 1 | R:R:D112 | R:R:Y443 | 10.34 | 3 | Yes | Yes | 9 | 9 | 1 | 1 | L:L:?1 | R:R:D112 | 7.12 | 3 | Yes | Yes | 0 | 9 | 0 | 1 | R:R:W164 | R:R:Y113 | 20.26 | 3 | Yes | Yes | 8 | 9 | 1 | 1 | R:R:I168 | R:R:Y113 | 3.63 | 3 | Yes | Yes | 8 | 9 | 2 | 1 | R:R:I187 | R:R:Y113 | 8.46 | 3 | Yes | Yes | 7 | 9 | 2 | 1 | R:R:Y113 | R:R:Y416 | 6.95 | 3 | Yes | Yes | 9 | 9 | 1 | 1 | R:R:Y113 | R:R:Y439 | 7.94 | 3 | Yes | Yes | 9 | 7 | 1 | 1 | L:L:?1 | R:R:Y113 | 19.46 | 3 | Yes | Yes | 0 | 9 | 0 | 1 | L:L:?1 | R:R:S116 | 7.87 | 3 | Yes | No | 0 | 8 | 0 | 1 | R:R:L163 | R:R:N117 | 4.12 | 3 | No | No | 8 | 9 | 2 | 2 | R:R:N117 | R:R:W164 | 6.78 | 3 | No | Yes | 9 | 8 | 2 | 1 | R:R:F409 | R:R:V120 | 5.24 | 3 | Yes | No | 9 | 9 | 2 | 2 | R:R:V120 | R:R:W413 | 4.9 | 3 | No | Yes | 9 | 9 | 2 | 1 | R:R:L163 | R:R:W164 | 5.69 | 3 | No | Yes | 8 | 8 | 2 | 1 | R:R:I168 | R:R:W164 | 4.7 | 3 | Yes | Yes | 8 | 8 | 2 | 1 | R:R:F189 | R:R:W164 | 3.01 | 0 | Yes | Yes | 8 | 8 | 2 | 1 | R:R:T199 | R:R:W164 | 6.06 | 0 | No | Yes | 9 | 8 | 2 | 1 | L:L:?1 | R:R:W164 | 11.94 | 3 | Yes | Yes | 0 | 8 | 0 | 1 | R:R:I168 | R:R:I187 | 2.94 | 3 | Yes | Yes | 8 | 7 | 2 | 2 | R:R:F189 | R:R:I187 | 7.54 | 0 | Yes | Yes | 8 | 7 | 2 | 2 | L:L:?1 | R:R:A203 | 4.13 | 3 | Yes | No | 0 | 9 | 0 | 1 | R:R:F204 | R:R:F409 | 4.29 | 3 | Yes | Yes | 9 | 9 | 2 | 2 | R:R:F204 | R:R:W413 | 7.02 | 3 | Yes | Yes | 9 | 9 | 2 | 1 | R:R:F204 | R:R:N417 | 20.54 | 3 | Yes | No | 9 | 9 | 2 | 2 | R:R:F409 | R:R:W413 | 9.02 | 3 | Yes | Yes | 9 | 9 | 2 | 1 | R:R:F409 | R:R:N445 | 3.62 | 3 | Yes | Yes | 9 | 9 | 2 | 2 | R:R:T412 | R:R:W413 | 4.85 | 3 | Yes | Yes | 9 | 9 | 2 | 1 | R:R:N445 | R:R:T412 | 8.77 | 3 | Yes | Yes | 9 | 9 | 2 | 2 | R:R:N445 | R:R:W413 | 7.91 | 3 | Yes | Yes | 9 | 9 | 2 | 1 | L:L:?1 | R:R:W413 | 12.94 | 3 | Yes | Yes | 0 | 9 | 0 | 1 | R:R:N417 | R:R:Y416 | 4.65 | 3 | No | Yes | 9 | 9 | 2 | 1 | R:R:V420 | R:R:Y416 | 6.31 | 0 | No | Yes | 8 | 9 | 2 | 1 | R:R:Y416 | R:R:Y439 | 2.98 | 3 | Yes | Yes | 9 | 7 | 1 | 1 | R:R:C442 | R:R:Y416 | 4.03 | 3 | No | Yes | 9 | 9 | 1 | 1 | L:L:?1 | R:R:Y416 | 12.29 | 3 | Yes | Yes | 0 | 9 | 0 | 1 | R:R:Y439 | R:R:Y443 | 3.97 | 3 | Yes | Yes | 7 | 9 | 1 | 1 | L:L:?1 | R:R:Y439 | 16.39 | 3 | Yes | Yes | 0 | 7 | 0 | 1 | R:R:W440 | R:R:Y443 | 3.86 | 3 | Yes | Yes | 9 | 9 | 2 | 1 | L:L:?1 | R:R:C442 | 9.71 | 3 | Yes | No | 0 | 9 | 0 | 1 | L:L:?1 | R:R:Y443 | 4.1 | 3 | Yes | Yes | 0 | 9 | 0 | 1 | |
Statistics | Value |
---|
Average Number Of Links | 10.00 | Average Number Of Links With An Hub | 7.00 | Average Interaction Strength | 10.59 | Average Nodes In Shell | 29.00 | Average Hubs In Shell | 19.00 | Average Links In Shell | 50.00 | Average Links Mediated by Hubs In Shell | 49.00 |
| ![](/psngpcr/ligands/ACH/ACH_7TRS_L_L_1_res_stats.svg) Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍) | ![](/psngpcr/ligands/ACH/ACH_7TRS_L_L_1_pos_stats.svg) Location of the nodes interacting with this ligand (click to enlarge 🔍) |
|